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Role of HRCT in detection and characterization of pulmonary abnormalities in pediatric patient’s undergone bone marrow transplant HRCT在小儿骨髓移植患者肺部异常的检测和表征中的作用
Pub Date : 2023-04-26 DOI: 10.37723/jumdc.v14i2.798
None Tahir Mehmood, None Sidra Tahir, None Sohail Shahzad, None Muhammad Arslan Farooq, None Syed Shayan Gilani
BACKGROUND & OBJECTIVE: Advancements in transplant regimens, alternative grafts, and new indications have improved bone marrow transplant activity with time. Our objective is to determine the pattern of pulmonary abnormalities using High resolution computed tomography (HRCT) chest scan and to determine the diagnostic accuracy (pulmonary abnormalities) and efficacy (in terms of radiation burden) of HRCT and X-rays after bone marrow transplant. METHODOLOGY: It was a descriptive case series conducted at the department of Radiology, POF Hospital, Wah Cantt over a duration of 8 months (January 2021-Augest 2021). A sample size of 20 patients was calculated using the WHO calculator. Patients were recruited through non-probability consecutive sampling. Patients were undergone through HRCT and chest X-rays for diagnostic accuracy and radiation burden measurement. Data was analyzed using SPSS version 24. Fisher exact test, Receiver Operating characteristic (ROC) Curve analysis and t-test was applied for statistical analysis. p-value ≤0.05 was considered significant. RESULTS: A total of 20 patient’s undergone bone marrow transplants were included in the study. The mean age of patients was 5. 25years.There were 11(55%) male and 9(45%) female in study. Pattern of pulmonary abnormalities was pleural effusion 2(10%) following nodules 1(5%), pneumonia patches 1(5%), ground glass opacities 1(5%) and septal thickening 1(5%). The diagnostic accuracy of HRCT was found to be high as compared to X-rays (88% vs 57% respectively). The mean radiation dose in HRCT and mean radiation dose in X-rays’ indicate a high radiation burden in HRCT (p≤0.001). CONCLUSION: Despite of high radiation burden in HRCT, it had high diagnostic accuracy as compared to X-rays.
背景,目的:随着时间的推移,移植方案、替代移植物和新适应症的进步改善了骨髓移植的活性。我们的目的是利用高分辨率计算机断层扫描(HRCT)胸部扫描确定肺部异常的模式,并确定骨髓移植后HRCT和x射线的诊断准确性(肺部异常)和有效性(根据辐射负担)。 方法:该研究是在华坎特POF医院放射科进行的描述性病例系列研究,为期8个月(2021年1月- 2021年8月)。使用世卫组织计算器计算了20例患者的样本量。采用非概率连续抽样方法招募患者。患者通过HRCT和胸部x线检查诊断准确性和辐射负荷测量。数据分析采用SPSS version 24。采用Fisher精确检验、受试者工作特征(ROC)曲线分析和t检验进行统计学分析。p值≤0.05被认为是显著的. 结果:共纳入20例骨髓移植患者。患者平均年龄5岁。25年。男性11例(55%),女性9例(45%)。肺部异常类型为胸膜积液2例(10%),其次为结节1例(5%),肺炎斑块1例(5%),磨玻璃影1例(5%)和间隔增厚1例(5%)。与x射线相比,HRCT的诊断准确性较高(分别为88%和57%)。HRCT的平均辐射剂量和x射线的平均辐射剂量表明HRCT的辐射负荷较高(p≤0.001)。 结论:HRCT虽然有较高的放射负荷,但与x线相比具有较高的诊断准确率。
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 METHODOLOGY: It was a descriptive case series conducted at the department of Radiology, POF Hospital, Wah Cantt over a duration of 8 months (January 2021-Augest 2021). A sample size of 20 patients was calculated using the WHO calculator. Patients were recruited through non-probability consecutive sampling. Patients were undergone through HRCT and chest X-rays for diagnostic accuracy and radiation burden measurement. Data was analyzed using SPSS version 24. Fisher exact test, Receiver Operating characteristic (ROC) Curve analysis and t-test was applied for statistical analysis. p-value ≤0.05 was considered significant.
 RESULTS: A total of 20 patient’s undergone bone marrow transplants were included in the study. The mean age of patients was 5. 25years.There were 11(55%) male and 9(45%) female in study. Pattern of pulmonary abnormalities was pleural effusion 2(10%) following nodules 1(5%), pneumonia patches 1(5%), ground glass opacities 1(5%) and septal thickening 1(5%). The diagnostic accuracy of HRCT was found to be high as compared to X-rays (88% vs 57% respectively). The mean radiation dose in HRCT and mean radiation dose in X-rays’ indicate a high radiation burden in HRCT (p≤0.001).
 CONCLUSION: Despite of high radiation burden in HRCT, it had high diagnostic accuracy as compared to X-rays.","PeriodicalId":33713,"journal":{"name":"Journal of University Medical Dental College","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135016688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Barriers in use of colostrum, Breast milk, and supplemental feed: assessing maternal Knowledge & practices 使用初乳、母乳和补充饲料的障碍:评估孕产妇的知识和做法
Pub Date : 2022-02-22 DOI: 10.37723/jumdc.v13i1.657
Hina Jawaid, Marriam Sheraz, Khudija Amna Arif, Zia Ul Hassan, Hina Akhter
BACKGROUND & OBJECTIVE: Colostrum and breast milk are not only highly nutritious but also a source of maternal antibodies for infants. We explore maternal awareness and barriers in use of colostrum and breast milk. METHODOLOGY: This cross-sectional study included mothers of children aged 3 years or less who visited primary care centers in urban and peri-urban areas of Lahore, Pakistan, between December 2020 to March 2021. RESULTS: A total of 384 mothers were included in the study, mean age was 28 years. 47% (n=179) had primary or secondary school education. Higher maternal education (p=0.05) and age were associated with better knowledge about the benefits of colostrum. Reasons for not giving colostrum among mothers without formal education (42%) were “it’s not clean milk”, while 38% of mothers with higher education give a reason they could not feed because find it difficult due to C-section. Use of supplemental feed was noted across all educational levels, 60% mothers with no educational background preferred bovine milk, whereas 79% of highly qualified ones preferred formula milk (p=0.00). The use of formula milk was more frequently observed in families with 100,000 PKR per month and above (p=0.00). 80% of mothers were unaware that bovine milk in infants can lead to anemia. CONCLUSION: There is inadequate knowledge, among mothers of all educational levels with reference to colostrum use and the relationship between consumption of bovine milk by infants and iron deficiency. Measures to improving maternal nutritional awareness and optimize infant feeding practices during antenatal visits are needed.
背景与目的:初乳和母乳不仅营养丰富,而且是婴儿母体抗体的来源。我们探讨产妇的意识和障碍,在使用初乳和母乳。方法:本横断面研究包括在2020年12月至2021年3月期间前往巴基斯坦拉合尔城市和城郊地区初级保健中心就诊的3岁或以下儿童的母亲。结果:共纳入384名母亲,平均年龄28岁。47% (n=179)接受过小学或中学教育。较高的母亲教育程度(p=0.05)和年龄与更好地了解初乳的益处相关。未受过正规教育的母亲不喂初乳的原因(42%)是“不干净的奶”,而受过高等教育的母亲中有38%的人给出了不能喂初乳的原因,因为剖腹产很难。所有教育水平的母亲都使用添加饲料,60%没有教育背景的母亲更喜欢牛奶,而79%的高教育水平的母亲更喜欢配方奶(p=0.00)。在每月PKR≥100,000的家庭中,配方奶的使用更为频繁(p=0.00)。80%的母亲不知道婴儿喝牛奶会导致贫血。结论:不同教育水平的母亲对初乳的使用以及婴儿食用牛奶与缺铁之间的关系了解不足。需要采取措施提高产妇的营养意识并优化产前检查期间的婴儿喂养方法。
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引用次数: 0
Listeriosis in pregnancy: a common yet underdiagnosed cause of febrile illness. 妊娠期李斯特菌病:发热性疾病的一种常见但未被确诊的病因。
Pub Date : 2022-02-22 DOI: 10.37723/jumdc.v13i1.709
Rubab Riaz, Rubina Shaheen
Abstract Food borne listeria infection is common in pregnancy as compared to general population because of the reduced immune defense mechanism in pregnancy. It may cause maternal morbidity and fetal mortality if not treated on time. Precooked meat and milk products are the main source of listeria.  The diagnosis is confirmed by blood culture and the infection is cured with ampicillin. This case report is of a patient presenting with febrile illness in second trimester of pregnancy. She gets promptly investigated for possible differential diagnosis, bacterial, viral and protozoal. Maternal complication increased till definitive management is offered.
摘要与普通人群相比,食源性李斯特菌感染在妊娠期很常见,因为妊娠期的免疫防御机制降低。如果不及时治疗,可能会导致产妇发病和胎儿死亡。预先烹制的肉类和奶制品是李斯特菌的主要来源。血液培养证实了诊断,并用氨苄青霉素治愈了感染。本病例报告是一名在妊娠中期出现发热性疾病的患者。她被迅速调查可能的鉴别诊断,细菌,病毒和原生动物。在提供明确的治疗之前,母体并发症增加。
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引用次数: 0
Research trends in polio during the last 50 years: a bibliometric analysis 过去50年小儿麻痹症的研究趋势:文献计量学分析
Pub Date : 2022-02-21 DOI: 10.37723/jumdc.v13i1.672
Muhammad Khan, Tauseef Ahmad, Muhammad Khan, M. Murad, M. Baig, Asmat Ali, Abdur Rehman
BACKGROUND & OBJECTIVE: Many polio cases have been reported in recent years, which strongly affect the Global Polio Eradication Initiative campaign. This study aimed to determine the global trends in polio research during the last fifty years. METHODOLOGY: An online search was conducted utilizing the Web of Science Core Collection database. The key term used was “Polio*" and the retrieved documents were assessed for several attributes. The required graphs were generated using OriginPro 2018. Furthermore, the data were plotted for co-authorship organizations, co-authorship countries, and co-occurrence author keywords network visualization mapping using VOSviewer software for windows. RESULTS: A total of 2,345 publications were included, cited 22,872 times. The year 2017 was the most frequent year with 162 (6.91%) publications. The paper authored by Nomoto and colleagues published in 1977 was the leading paper with 237 citations. In total, Vaccine was the leading journal with 168 (7.16%) publications, followed by Journal of Infectious Diseases 106 (4.52%), and Lancet 77 (3.28%). The included publications were published from 132 countries, of which 44 countries contributed ≥10 publications. The United States of America was the leading country with the highest number of publications (n=740, 31.56%), followed by India (n=215, 9.17%), and England (n=180, 7.68%). CONCLUSION: This study provide researchers and policy makers with a comprehensive list of the key bibliometric characteristics and major contribution in polio research. Majority of the studies were published in developed countries. The developing countries need to make strong research collaborations with developed countries.
背景与目的:近年来报告了许多脊髓灰质炎病例,这对全球根除脊髓灰质炎倡议运动产生了重大影响。这项研究旨在确定过去五十年脊髓灰质炎研究的全球趋势。方法:利用Web of Science核心收藏数据库进行在线搜索。使用的关键术语是“脊髓灰质炎*”,并对检索到的文档进行了几个属性的评估。所需的图表是使用OriginPro 2018生成的。此外,使用windows的VOSviewer软件绘制了合著组织、合著国家和共现作者关键字网络可视化映射的数据。结果:共收录2345篇文献,引用22872次。2017年是最频繁的一年,共有162份(6.91%)出版物。Nomoto及其同事于1977年发表的这篇论文是领先的论文,引用次数为237次。总的来说,《疫苗》是领先的期刊,共有168篇(7.16%)出版物,其次是《传染病杂志》106篇(4.52%)和《柳叶刀》77篇(3.28%)。收录的出版物来自132个国家,其中44个国家贡献了≥10篇出版物。美国是出版数量最多的国家(n=740,31.56%),其次是印度(n=215,9.17%)和英国(n=180,7.68%)。大多数研究发表在发达国家。发展中国家需要与发达国家进行强有力的研究合作。
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引用次数: 3
Time to rationalize the use of antibiotics 是时候合理使用抗生素了
Pub Date : 2022-02-21 DOI: 10.37723/jumdc.v13i1.721
Aisha Sajid
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引用次数: 0
COVID-19 pandemic and the use of tele-health by pediatricians and pediatric post graduate residents COVID-19大流行与儿科医生和儿科研究生住院医师远程医疗的使用
Pub Date : 2022-02-21 DOI: 10.37723/jumdc.v13i1.637
Tehreem Fatima, Zaib Nasir, AbdulAhad Jamshaid, Hina Ayesha
BACKGROUND & OBJECTIVE: During the COVID-19 pandemic, burden on healthcare facilities has increased worldwide; which has led to acceptance of the ‘telehealth services’ by the pediatricians. Objective of this study was to determine the impact on frequency of use of tele-health services by pediatricians during the COVID-19 pandemic; and to determine the factors promoting and preventing the use of tele-health services by pediatricians. METHODOLOGY: This descriptive cross-sectional study was carried out from August 2020 to January 2021 among the pediatricians of Children Hospital Faisalabad and other affiliated hospitals of Faisalabad Medical University, Pakistan. An e-questionnaire was circulated among 357 pediatricians, which was filled and submitted by 114 pediatricians online. Demographic details and other data were collected and analyzed by SPSS v.20. P-value <0.05 was taken as significant. RESULTS: Out of 114 participants, 29(25.4%) paediatricians were already using Telehealth before the COVID-19 pandemic. Whereas, 101(88.6%) participants used Telehealth during the pandemic. There was an increase in frequency of telehealth use during the pandemic by 72(63.2%) paediatricians (p-value= 0.037). Most common factor promoting the use of telehealth during pandemic was ‘decreased chance of cross infection and maintenance of social distancing’. Most frequent factor preventing its use was ‘lack of confidence on virtual examination findings’. CONCLUSION: Telehealth provided an effective means of practicing social distancing by the paediatricians without any breach in healthcare provision. However, there are a few factors contributing to hesitancy towards it. Therefore, more platforms must be provided and incentives to be given to paediatricians to promote the use of telehealth.
背景与目的:在2019冠状病毒病大流行期间,全球医疗机构的负担有所增加;这导致儿科医生接受了“远程医疗服务”。本研究的目的是确定COVID-19大流行期间对儿科医生使用远程医疗服务频率的影响;并确定促进和阻止儿科医生使用远程保健服务的因素。方法:本描述性横断面研究于2020年8月至2021年1月在巴基斯坦费萨拉巴德儿童医院和费萨拉巴德医科大学其他附属医院的儿科医生中进行。在357名儿科医生中分发了一份电子问卷,由114名儿科医生在线填写和提交。使用SPSS v.20收集人口统计细节等数据并进行分析。p值<0.05为显著性。结果:在114名参与者中,29名(25.4%)儿科医生在COVID-19大流行之前已经在使用远程医疗。101名(88.6%)参与者在大流行期间使用了远程医疗。在大流行期间,远程医疗的使用频率增加了72名(63.2%)儿科医生(p值= 0.037)。在大流行期间促进使用远程医疗的最常见因素是“减少交叉感染的机会和保持社交距离”。最常见的阻碍其使用的因素是“对虚拟检查结果缺乏信心”。结论:远程医疗为儿科医生提供了一种有效的保持社会距离的手段,而不会破坏医疗保健服务。然而,有几个因素导致了对它的犹豫。因此,必须提供更多的平台,并向儿科医生提供奖励,以促进远程保健的使用。
{"title":"COVID-19 pandemic and the use of tele-health by pediatricians and pediatric post graduate residents","authors":"Tehreem Fatima, Zaib Nasir, AbdulAhad Jamshaid, Hina Ayesha","doi":"10.37723/jumdc.v13i1.637","DOIUrl":"https://doi.org/10.37723/jumdc.v13i1.637","url":null,"abstract":"BACKGROUND & OBJECTIVE: During the COVID-19 pandemic, burden on healthcare facilities has increased worldwide; which has led to acceptance of the ‘telehealth services’ by the pediatricians. Objective of this study was to determine the impact on frequency of use of tele-health services by pediatricians during the COVID-19 pandemic; and to determine the factors promoting and preventing the use of tele-health services by pediatricians. \u0000METHODOLOGY: This descriptive cross-sectional study was carried out from August 2020 to January 2021 among the pediatricians of Children Hospital Faisalabad and other affiliated hospitals of Faisalabad Medical University, Pakistan. An e-questionnaire was circulated among 357 pediatricians, which was filled and submitted by 114 pediatricians online. Demographic details and other data were collected and analyzed by SPSS v.20. P-value <0.05 was taken as significant. \u0000RESULTS: Out of 114 participants, 29(25.4%) paediatricians were already using Telehealth before the COVID-19 pandemic. Whereas, 101(88.6%) participants used Telehealth during the pandemic. There was an increase in frequency of telehealth use during the pandemic by 72(63.2%) paediatricians (p-value= 0.037). Most common factor promoting the use of telehealth during pandemic was ‘decreased chance of cross infection and maintenance of social distancing’. Most frequent factor preventing its use was ‘lack of confidence on virtual examination findings’. \u0000CONCLUSION: Telehealth provided an effective means of practicing social distancing by the paediatricians without any breach in healthcare provision. However, there are a few factors contributing to hesitancy towards it. Therefore, more platforms must be provided and incentives to be given to paediatricians to promote the use of telehealth.","PeriodicalId":33713,"journal":{"name":"Journal of University Medical Dental College","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48072850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding, Oral Hygiene Practices, Behaviors and Myths to deal with Toothache in Rural Areas 农村地区应对牙痛的认识、口腔卫生习惯、行为和误区
Pub Date : 2022-02-21 DOI: 10.37723/jumdc.v13i1.575
Sarang Suresh Hotchandani, Priya Rani Harjani, Suneel Kumar Punjabi, Mowaffaq Abdullmomen Al Absi, Hafiz Mahmood Azam, Aswad Ahmed
BACKGROUND & OBJECTIVE: In Pakistan, there is lack of awareness to maintain oral hygiene and cleaning of oral structures. The current study aims to unveil homemade remedies and self-care methods followed by a majority of the rural population to cure dental pain in Sindh, Pakistan.  METHODOLOGY: This cross-sectional descriptive study was conducted at dental OPD of the Secondary Health Care Facility of Sindh, Pakistan, by following a random sample selection approach.  Patients from both genders representing oro-dental problems of ages ≥ 5 year were included in the study. Patient’s clinical and demographic data was collected, and further descriptive data analysis was done by using Microsoft Excel 2016. RESULTS: A total of 1627 patients fulfilled the inclusion criteria of the study. The highest number of cases (73.81%) were belonging to the age group 15-49 years, affirming that adults are at greater risk of developing toothache and dental pain. Surprisingly, about 78.97% patients had never visited any physician for seeking the clinical services. Similarly, 37.18 % of patients did not use any cleaning substance while 22.12 % patients preferred miswak for cleaning of their teeth. Only 2.95 % of patients visited dentists for proper care. CONCLUSION: Current research report concludes that from all the confirmed toothache cases, 22.13 % of patients sought care from general physicians in parallel with 22.34 % patients were preferring religious spells to manage their dental pain, which further multiplied the disease rate. However, general physicians at primary healthcare settings have limited knowledge and training in managing dental pain.
背景与目的:在巴基斯坦,人们缺乏保持口腔卫生和清洁口腔结构的意识。目前的研究旨在揭示巴基斯坦信德省大多数农村人口为治疗牙痛而采用的自制疗法和自我护理方法。方法:这项横断面描述性研究是在巴基斯坦信德省二级医疗机构的牙科门诊部进行的,采用随机样本选择方法。研究中包括了年龄≥5岁的男女口腔问题患者。收集患者的临床和人口统计数据,并使用Microsoft Excel 2016进行进一步的描述性数据分析。结果:共有1627名患者符合本研究的纳入标准。病例最多(73.81%)属于15-49岁年龄组,这肯定了成年人患牙痛和牙痛的风险更大。令人惊讶的是,约78.97%的患者从未因寻求临床服务而拜访过任何医生。同样,37.18%的患者没有使用任何清洁物质,而22.12%的患者更喜欢使用miswak清洁牙齿。只有2.95%的患者去牙医那里寻求适当的护理。结论:目前的研究报告得出结论,在所有确诊的牙痛病例中,22.13%的患者向普通医生寻求治疗,而22.34%的患者更喜欢宗教咒语来治疗牙痛,这进一步增加了患病率。然而,初级保健机构的普通医生在治疗牙痛方面的知识和培训有限。
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引用次数: 2
A comparative study of postoperative airway management between traditional nasal packing and modified nasal airway after nasal surgeries 传统鼻填塞与改良鼻气道术后气道管理的比较研究
Pub Date : 2022-02-21 DOI: 10.37723/jumdc.v13i1.659
Muhammad Saleem, Baber Rafiq Khan, Sarwat Bibi, Humaira Ahmad, Muhammad Hamza Rana
BACKGROUND & OBJECTIVE: One of the most common challenging complications after nasal surgeries is maintaining airways. The study aimed to use an alternative technique instead of nasal packing in the immediate postoperative period undergoing different nasal surgery under general anesthesia regarding airway management. METHODOLOGY: An interventional study was conducted at Aziz Fatimah Trust Hospital, Faisalabad, from  March 20, 2018, to January 31, 2019. A total of 100 participants were enrolled in the study divided into two groups (A & B), 50 each. Group A patients were treated postoperatively with a modified nasal airway devised with a Nelton catheter and Group B patients with traditional nasal packing. The participants were assessed on different parameters which were statistically compared and analyzed. RESULTS: Group Descriptive statistics revealed that the Mean±SD of the age of group A and group B patients was 24.28±9.72 and 26.68±11.09 respectively, which had no significant difference between them {p-value (0.008)}. The postoperative parameters such as patient's comfort and sleep, surgeon satisfaction, ease of suction through Nelton catheter, and oxygen saturation were evaluated as significant variables in the evaluation of the study. p-value ≤0.05 and ≤0.005 were considered as significant and highly significant respectively. CONCLUSION: This modified nasal airway has proven to be easily replicable and reliable, and a cost-effective measure elucidated as a potential and exclusive outcome of the present study.
背景与目的:鼻腔手术后最常见的并发症之一是气道的维持。本研究的目的是在全身麻醉下进行不同鼻部手术后立即使用一种替代鼻塞的技术来处理气道管理。方法:于2018年3月20日至2019年1月31日在费萨拉巴德Aziz Fatimah信托医院进行了一项介入性研究。共有100名参与者参加了这项研究,分为两组(A和B),每组50人。A组患者术后采用改良鼻道导气管,B组患者术后采用传统鼻填充物。对参与者进行不同参数的评估,并进行统计比较和分析。结果:组描述性统计显示,A组和B组患者年龄均值±SD分别为24.28±9.72和26.68±11.09,两组间差异无统计学意义{p值(0.008)}。术后参数如患者的舒适度和睡眠、外科医生的满意度、通过Nelton导管吸引的难易程度、血氧饱和度作为评价研究的重要变量。p值≤0.05为显著,p值≤0.005为极显著。结论:这种改良的鼻导气管已被证明是易于复制和可靠的,并且是一种具有成本效益的措施,是本研究的潜在和唯一的结果。
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引用次数: 0
Association between artificially sweetened beverages consumption and changes in body mass index among children 儿童饮用人工加糖饮料与体重指数变化之间的关系
Pub Date : 2022-02-21 DOI: 10.37723/jumdc.v13i1.685
Muhammad Bilal Arshad, Muhammad Usman Sheikh, Muhammad Afzal, Aneela Amjad, Shahzeb Patoli, Muhammad Behzad Salahuddin
BACKGROUND & OBJECTIVE: Poor food quality and choices are a major concern in the modern life style and increased consumption of sweetened and artificially sweetened beverages have been implicated as contributing factors for obesity. The objective of this study is to determine the association between the consumption of artificially sweetened beverages and changes in body mass index among children. METHODOLOGY: Data on the consumption of artificially sweetened beverages consumption and BMI for 13,287 children was analyzed for exposure and outcome from Millennium Cohort Study (MCS). The association between frequency of ASB consumption and BMI was quantified using demographics and linear regression analysis. The linear regression analysis was done adjusting demographic, socioeconomic variables and confounding factors of frequency of physical activity. Regression analysis was conducted using survey weights to account for the complex sampling design. RESULTS:  Adjusted linear regression for demographical and socioeconomic variables showed that more frequent consumption of ASB was associated with a significant increase in BMI. As the frequency of ASB increased, BMI significantly increased by 0.69-1.06 units in categories (p<0.01). Regression analysis adjusted for frequency of physical activity also showed an increase of BMI by 0.36 units (p<0.01) with the highest frequency of ASB consumption. CONCLUSION: Higher consumption of artificially sweetened beverages causes an increase in BMI among UK children.
背景与目的:不良的食品质量和选择是现代生活方式的一个主要问题,加糖和人工加糖饮料的消费增加被认为是肥胖的一个因素。这项研究的目的是确定食用人工加糖饮料与儿童体重指数变化之间的关系。方法:对13287名儿童的人工加糖饮料消费和BMI数据进行了分析,以了解千禧队列研究(MCS)的暴露和结果。使用人口统计学和线性回归分析量化ASB消费频率与BMI之间的关系。调整人口统计学、社会经济变量和运动频率的混杂因素,进行线性回归分析。使用调查权重进行回归分析,以解释复杂的抽样设计。结果:人口统计学和社会经济变量的调整线性回归显示,更频繁地服用ASB与BMI显著增加有关。随着ASB发生频率的增加,BMI各类别均显著升高0.69 ~ 1.06单位(p<0.01)。经身体活动频率调整后的回归分析也显示,ASB消费频率最高时,BMI增加0.36单位(p<0.01)。结论:大量饮用人工加糖饮料导致英国儿童体重指数上升。
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引用次数: 1
Trend analysis of COVID-19 cases in Pakistan 巴基斯坦新冠肺炎病例趋势分析
Pub Date : 2022-02-21 DOI: 10.37723/jumdc.v13i1.655
Sumera Shareef, Shumiala Akhtar, Naima Tufail, Fiaz Ahmad, Muhammad Imran shakoor
BACKGROUND & OBJECTIVE: Statistical models play a significant role in understanding the trend, level and trajectory of infectious diseases and provide the foundation to formulate effective policies and timely intervention, so that the morbidity and mortality due to these diseases can be declined. This study aimed to uncover the trend and proposing a forecasting model for daily expected outbreaks due to COVID-19 of fourth spike in Pakistan.  METHODOLOGY: This study is primarily based on a secondary data of COVID-19 daily confirmed outbreaks. The two-month (1st June to 31st July 2021) time series data is recorded and available from COVID-19 health advisory platform by Ministry of National Health Services Regulation and Coordination official website. Descriptive and time series analysis (ARIMA, exponential smoothing models) were applied. The analysis was carried out using R programming language. RESULTS: The highest (5026) and the lowest (663), COVID-19 confirm cases reported on 31 July 2021 and 21 June 2021 respective, whereas the average confirmed cases were 1830 [762-2898] per day. Four different time series models are executed namely ARIMA, Brown, Holt and Winter.  Among competitive models, ARIMA (0, 2, 1) is found to be an optimum forecasting model, selected by using auto ARIMA function with least root mean square error. A day ahead forecast is obtained under the selected ARIMA model and yielded that COVID-19 confirmed outbreaks is expected to increase about 3.1% per day. CONCLUSION: COVID-19 outbreaks are expected to rise in Pakistan and ARIMA (0, 2, 1) is an optimum forecasting model for daily COVID-19 outbreaks.
背景与目的:统计模型对了解传染病的趋势、水平和发展轨迹具有重要作用,为制定有效的政策和及时的干预提供依据,从而降低传染病的发病率和死亡率。这项研究旨在揭示这一趋势,并提出一个预测模型,预测巴基斯坦因COVID-19导致的每日预期爆发的第四次高峰。方法:本研究主要基于每日确诊的COVID-19暴发的二级数据。这两个月(2021年6月1日至7月31日)的时间序列数据由国家卫生服务监管和协调部官方网站从COVID-19健康咨询平台记录和提供。采用描述性和时间序列分析(ARIMA,指数平滑模型)。使用R编程语言进行分析。结果:2021年7月31日和2021年6月21日报告的新冠肺炎确诊病例最多(5026例),最少(663例),平均每天确诊病例1830例[762 ~ 2898]例。执行了ARIMA、Brown、Holt和Winter四种不同的时间序列模型。在竞争模型中,ARIMA(0, 2, 1)是最优的预测模型,使用均方根误差最小的自动ARIMA函数选择。在选定的ARIMA模型下进行了一天前的预测,结果显示,预计COVID-19确诊疫情每天将增加约3.1%。结论:预计巴基斯坦2019冠状病毒病疫情将呈上升趋势,ARIMA(0,2,1)是预测日疫情的最佳模型。
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引用次数: 1
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Journal of University Medical Dental College
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