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Is it possible to have a risk scoring system that provides early warning of the poor prognosis in COVID-19? 是否有可能建立一个风险评分系统,为COVID-19的不良预后提供早期预警?
Pub Date : 2022-01-01 DOI: 10.14744/scie.2022.46794
Sinem Özcan
Objective: In our study, we aimed to determine the factors associated with poor outcome by evaluating the data of possible/definite Coronavirus 2019 (COVID-19) cases coming to the emergency department in two centers and to establish a risk scoring system. Methods: This study has been designed as a retrospective study performed on COVID-19 cases. Patients’ sociodemographic data, complaints, vital signs, laboratory parameters, service/ intensive care admission status, and the presence of death were analyzed. Results: A total of 436 patients were included in the study. We divided the cases into two groups in terms of poor outcome. The factors associated with poor outcome such as the presence of comorbid disease (p=0.001), being 50 years and older (p<0.001), symptoms of shortness of breath (p<0.001), saturation value <95% (p<0.001), neutrophil count >7×109 L–1 (p=0.006), lymphocyte count <1.1×109 L–1 (p=0.020), procalcitonin value ≥0.015 ng/mL (p=0.001), D-dimer value ≥500 mg/L (p=0.009) were found to be statistically significant. Conclusion: The scoring system we have created is considered to be a comprehensive, easily applicable, and reliable method in determining the prognosis and the treatment strategy. (English) [ FROM AUTHOR] Amaç: Çalışmamızda iki merkezin acil servisine başvuran olası/kesin COVID-19 olgularının verilerini değerlendirerek kötü prognoz ilişkili faktörleri belirlemeyi ve risk skorlama sistemi oluşturmayı amaçladık. Gereç ve Yöntem: Bu çalışma, COVID-19 olgularında geriye dönük olarak tasarlandı. Hastaların sosyodemografik verileri, şikayetleri, vital bulguları, laboratuvar bulguları, servis/yoğun bakım yatış durumu, ve ölüm varlığı analiz edilmiştir. Bulgular: Çalışmaya 436 hasta dahil edildi. Olguları kötü prognoz açısından iki gruba ayırdık kötü prognozla ilişkili faktörler değerlendirildiğinde;komorbidite varlığı (p=0.001), 50 yaş ve üzeri olmak (p<0.001), nefes darlığı semptomunun olması (p<0.001), oksijen satürasyon değerinin %95 altında olması (p<0.001), nötrofil sayısının 7x109/L–1 üzerinde olması (p=0.006), lenfosit sayısının 1.1×109/L–1 altında olması (p=0.020), Prokalsitonin düzeyinin 0.015 ng/mL ve üzerinde olması (p=0.001), D dimer değerinin 500 mg/L ve üzerinde olması (p=0.009) istatistiksel olarak anlamlı bulundu. Sonuç: Kapsamlı risk skorlama sistemimizi oluşturduk. Modelimiz sekiz parametreden oluşmaktadır. Kötü prognoza sahip hastaların puan ortalamaları diğer hastalara göre anlamlı derecede yüksekti. Oluşturduğumuz skorlama sisteminin prognoz ve tedavi stratejisinin belirlenmesinde kapsamlı, kolay uygulanabilir ve güvenilir bir yöntem olduğu düşünülmektedir. (Turkish) [ FROM AUTHOR] Copyright of Southern Clinics of Istanbul Eurasia is the property of KARE Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warr
目的:本研究旨在通过对两个中心可能/确诊的2019冠状病毒肺炎(COVID-19)病例来急诊科就诊的数据进行评估,确定影响预后不良的相关因素,并建立风险评分系统。方法:本研究采用回顾性研究方法对COVID-19病例进行研究。分析患者的社会人口统计数据、主诉、生命体征、实验室参数、服务/重症监护住院状态和死亡情况。结果:共纳入436例患者。我们根据不良结果将这些病例分为两组。存在合并症(p=0.001)、50岁及以上(p7×109 L - 1 (p=0.006)、淋巴细胞计数<1.1×109 L - 1 (p=0.020)、降钙素原值≥0.015 ng/mL (p=0.001)、d -二聚体值≥500 mg/L (p=0.009)等不良预后相关因素均具有统计学意义。结论:所建立的评分系统是一种全面、简便、可靠的判断预后和治疗策略的方法。(中文)[来自作者]Amaç: Çalışmamızda iki merkezin acil servisine ba vuran olasyi /kesin COVID-19 olgularının verilerini değerlendirerek kötü prognoz ilikili faktörleri belirlemeyi ve risk skorlama sistemi oluturmayyi amaçladık。Gereç ve Yöntem: Bu çalışma, COVID-19 olgularında geriye dönük olarak tasarlandi。Hastaların sosyodemografik verileri,。Bulgular: Çalışmaya 436 hasta dahil edildi。Olgularıkotu prognoz acı年代ından iki gruba ayırd kıkotu prognozla伊犁ş基利faktorler değerlendirildiğ印度;komorbidite varlığı(p = 0.001), 50丫şve uzeri olmak (p < 0.001), nef灵魂ığısemptomunun olması(p < 0.001), oksijen saturasyon değerinin % 95 altında olması(p < 0.001), notrofil说ı年代ını7 x109 / l - 1 uzerinde olması(p = 0.006), lenfosit说ı年代ını1.1×109 / l - 1 altında olması(p = 0.020), Prokalsitonin duzeyinin 0.015 ng / mL ve uzerinde olması(p = 0.001),D二聚体değerinin 500 mg/L ve zerinde olmasyi (p=0.009)具有统计学意义。Sonuç: kapsamlli risk skorlama sistemimizi oluturduk。模型化sekiz参数化oluşmaktadır。Kötü prognoza sahip hastaların puan ortalamalaryi diğer hastalara göre anlamlyi derecede y ksekti。Oluşturduğumuz skorlama sisteminin prognoz ve tedavi stratejisinin belirlenmesinde kapsamlir, kolay uygulanabilir ve g venilir bir yöntem olduğu d nndir lmektedir。[来自作者]伊斯坦布尔欧亚南方诊所的版权是KARE出版社的财产,未经版权所有者的明确书面许可,其内容不得复制或通过电子邮件发送到多个网站或发布到listserv。但是,用户可以打印、下载或通过电子邮件发送文章供个人使用。这可以删节。对副本的准确性不作任何保证。用户应参阅原始出版版本的材料的完整。(版权适用于所有人。)
{"title":"Is it possible to have a risk scoring system that provides early warning of the poor prognosis in COVID-19?","authors":"Sinem Özcan","doi":"10.14744/scie.2022.46794","DOIUrl":"https://doi.org/10.14744/scie.2022.46794","url":null,"abstract":"Objective: In our study, we aimed to determine the factors associated with poor outcome by evaluating the data of possible/definite Coronavirus 2019 (COVID-19) cases coming to the emergency department in two centers and to establish a risk scoring system. Methods: This study has been designed as a retrospective study performed on COVID-19 cases. Patients’ sociodemographic data, complaints, vital signs, laboratory parameters, service/ intensive care admission status, and the presence of death were analyzed. Results: A total of 436 patients were included in the study. We divided the cases into two groups in terms of poor outcome. The factors associated with poor outcome such as the presence of comorbid disease (p=0.001), being 50 years and older (p<0.001), symptoms of shortness of breath (p<0.001), saturation value <95% (p<0.001), neutrophil count >7×109 L–1 (p=0.006), lymphocyte count <1.1×109 L–1 (p=0.020), procalcitonin value ≥0.015 ng/mL (p=0.001), D-dimer value ≥500 mg/L (p=0.009) were found to be statistically significant. Conclusion: The scoring system we have created is considered to be a comprehensive, easily applicable, and reliable method in determining the prognosis and the treatment strategy. (English) [ FROM AUTHOR] Amaç: Çalışmamızda iki merkezin acil servisine başvuran olası/kesin COVID-19 olgularının verilerini değerlendirerek kötü prognoz ilişkili faktörleri belirlemeyi ve risk skorlama sistemi oluşturmayı amaçladık. Gereç ve Yöntem: Bu çalışma, COVID-19 olgularında geriye dönük olarak tasarlandı. Hastaların sosyodemografik verileri, şikayetleri, vital bulguları, laboratuvar bulguları, servis/yoğun bakım yatış durumu, ve ölüm varlığı analiz edilmiştir. Bulgular: Çalışmaya 436 hasta dahil edildi. Olguları kötü prognoz açısından iki gruba ayırdık kötü prognozla ilişkili faktörler değerlendirildiğinde;komorbidite varlığı (p=0.001), 50 yaş ve üzeri olmak (p<0.001), nefes darlığı semptomunun olması (p<0.001), oksijen satürasyon değerinin %95 altında olması (p<0.001), nötrofil sayısının 7x109/L–1 üzerinde olması (p=0.006), lenfosit sayısının 1.1×109/L–1 altında olması (p=0.020), Prokalsitonin düzeyinin 0.015 ng/mL ve üzerinde olması (p=0.001), D dimer değerinin 500 mg/L ve üzerinde olması (p=0.009) istatistiksel olarak anlamlı bulundu. Sonuç: Kapsamlı risk skorlama sistemimizi oluşturduk. Modelimiz sekiz parametreden oluşmaktadır. Kötü prognoza sahip hastaların puan ortalamaları diğer hastalara göre anlamlı derecede yüksekti. Oluşturduğumuz skorlama sisteminin prognoz ve tedavi stratejisinin belirlenmesinde kapsamlı, kolay uygulanabilir ve güvenilir bir yöntem olduğu düşünülmektedir. (Turkish) [ FROM AUTHOR] Copyright of Southern Clinics of Istanbul Eurasia is the property of KARE Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warr","PeriodicalId":33982,"journal":{"name":"Southern Clinics of Istanbul Eurasia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67339593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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{"title":"Composite Mantle Cell Lymphoma and EBV Positive Classical Hodgkin Lymphoma: Case Report","authors":"N. Barısık","doi":"10.14744/scie.2022.64497","DOIUrl":"https://doi.org/10.14744/scie.2022.64497","url":null,"abstract":"","PeriodicalId":33982,"journal":{"name":"Southern Clinics of Istanbul Eurasia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67340603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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{"title":"Effects Of Bladder Diverticulum On Storage And Extraction Phase Of The Lower Urıinary System: Urodynamic And Clinical Evaluation","authors":"Burcu Sevinc","doi":"10.14744/scie.2022.74429","DOIUrl":"https://doi.org/10.14744/scie.2022.74429","url":null,"abstract":"","PeriodicalId":33982,"journal":{"name":"Southern Clinics of Istanbul Eurasia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67341688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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{"title":"Assessment of Hepatic Steatosis Using Clinical and Laboratory Parameters with Computed Tomography Comparison in Living Liver Donor Candidates","authors":"Talha Sarıgöz","doi":"10.14744/scie.2022.54037","DOIUrl":"https://doi.org/10.14744/scie.2022.54037","url":null,"abstract":"","PeriodicalId":33982,"journal":{"name":"Southern Clinics of Istanbul Eurasia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67340144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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{"title":"Association between histologic subtypes of non-small cell lung cancer and survival: Retrospective cohort analysis of 1887 patients","authors":"M. Buz","doi":"10.14744/scie.2022.59862","DOIUrl":"https://doi.org/10.14744/scie.2022.59862","url":null,"abstract":"","PeriodicalId":33982,"journal":{"name":"Southern Clinics of Istanbul Eurasia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67340377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Southern Clinics of Istanbul Eurasia
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