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Journal of Neonatal Surgery最新文献

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Heteropagus parasitic twins – a case of omphalopagus with major omphalocele and congenital heart disease 异斜交寄生双胞胎-脐斜交伴大脐膨出合并先天性心脏病1例
Q4 Medicine Pub Date : 2022-07-09 DOI: 10.47338/jns.v11.1091
Sofia Morão, Filipa Marujo, P. Loureiro, D. Virella, R. Alves
A 3250g, female second twin, known antenatally to have an omphalocele and interventricular communication, was delivered by elective cesarean section (pelvic 1st twin) to a 33-year-old, G1P1, mother at 36 weeks’ gestation, at the referral tertiary level maternity of a university hospital center. It was a monochorionic diamniotic pregnancy through a donor in vitro fertilization. No obvious exposure to teratogens was documented during gestation. Both fetuses had negative karyotype for T21 and T13 and normal microarray.
一对3250克的女性第二对双胞胎,出生前已知有脐膨出和室间沟通,在一所大学医院中心的转诊三级产科中心通过选择性剖宫产(骨盆第一对双胞胎)产下给一位33岁的G1P1母亲,她怀孕36周。这是一例通过供体体外受精进行的单绒毛膜异位妊娠。妊娠期未发现明显的致畸物暴露。两个胎儿的T21和T13染色体组型均为阴性,微阵列正常。
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引用次数: 0
Managing sacrococcygeal teratoma in a resource constrained setting 在资源有限的环境中处理骶尾部畸胎瘤
Q4 Medicine Pub Date : 2022-06-28 DOI: 10.47338/jns.v11.1097
Jeanière Tumusifu Manegabe, Florent Tshiwid A Zeng, G. M. Balemba, Bijou Safi Matabaro, Etienne Kajibwami Birindwa, Léon-Emmanuel Mubenga Mukengeshai, Fabrice Cikomola Gulimwentuga
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引用次数: 0
Large defect size is associated with 30-day mortality following surgical repair of congenital diaphragmatic hernia 先天性膈疝手术修复术后30天死亡率与缺损大小有关
Q4 Medicine Pub Date : 2022-06-26 DOI: 10.47338/jns.v11.1098
M. Zouari, H. Ben Ameur, E. Krichen, N. Kraiem, M. Ben Dhaou, R. Mhiri
Congenital diaphragmatic hernia (CDH) is one of the most challenging neonatal conditions occurring in 3 in 10000 live births. [1] Despite considerable recent advances in perinatal resuscitation and neonatal care, CDH remains an important cause of mortality with rates ranging from 25% to 50%. [2-5] The leading causes of death in these patients are persistent pulmonary hypertension and severe lung hypoplasia. [6] Many researchers have studied the association between prognostic factors and mortality following surgical repair of CDH. However, these prognostic factors did not find widespread use due to conflicting results. Moreover, most studies regarding CDH outcomes are from developed countries. The management of these patients in developing countries is more challenging. In Tunisia, as in many developing countries, extracorporeal membrane oxygenation and synthetic patches are not available. The aim of this study was to assess risk factors for 30-day mortality following surgical repair of congenital diaphragmatic hernia in a single center in Tunisia.
先天性膈疝(CDH)是最具挑战性的新生儿疾病之一,每10000例活产中就有3例发生。[1] 尽管最近在围产期复苏和新生儿护理方面取得了相当大的进展,但CDH仍然是死亡率的重要原因,死亡率在25%至50%之间。[2-5]这些患者的主要死因是持续性肺动脉高压和严重的肺发育不全。[6] 许多研究人员已经研究了CDH手术修复后预后因素与死亡率之间的关系。然而,由于结果相互矛盾,这些预后因素并没有得到广泛应用。此外,大多数关于CDH结果的研究都来自发达国家。发展中国家对这些患者的管理更具挑战性。与许多发展中国家一样,突尼斯没有体外膜肺氧合和合成贴片。本研究的目的是在突尼斯的一个单一中心评估先天性膈疝手术修复后30天死亡率的风险因素。
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引用次数: 0
Risk factors for early surgical intervention in neonates with gastroesophageal reflux disease 新生儿胃食管反流病早期手术干预的危险因素
Q4 Medicine Pub Date : 2022-06-24 DOI: 10.47338/jns.v11.1033
Shady S. Shokry, K. El-Asmar, M. Dahab, T. Hassan
Background: Surgical intervention in neonates with Gastro-esophageal Reflux Disease (GERD) is usually reserved for failure of medical management or those having life-threatening complications of GERD. The optimal timing of intervention is still debatable.  We aimed to identify the high-risk neonates with GERD requiring early surgical intervention.Methods: This prospective cohort study was conducted at NICU and Pediatric Surgery Department, Ain Shams University, from June 2017 to June 2020, and enrolled the neonates and infants below 2 months with symptoms and signs suggestive of GERD. Demographic data, clinical history, medical management, need for antireflux surgery, and outcomes were recorded.Results: In this study, 40 patients were enrolled and all were started on medical treatment. After the failure of medical management or life-threatening complications, 12 of these underwent anti-reflux surgery. In the medical group, six patients suffered from major complications (bronchopulmonary dysplasia and sepsis) and four mortalities. In the surgical group, three mortalities related to the development of bronchopulmonary dysplasia due to prolonged ventilation prior to surgery were recorded. The need for surgical intervention was significantly associated with younger gestational age (p = 0.001), younger age at presentation (p = 0.006), and lower weight at presentation (p = 0.034).Conclusion: Medical treatment of more than 35 days with unsatisfactory response, low birth weight, gestational age (≤32 weeks), and NICU admission in the first 10 days of life are considered high-risk factors for early anti-reflux surgery in neonates.
背景:新生儿胃食管反流病(GERD)的手术干预通常用于药物治疗失败或有危及生命的GERD并发症。干预的最佳时机仍有争议。我们的目的是确定需要早期手术干预的高危新生儿GERD。方法:本前瞻性队列研究于2017年6月至2020年6月在艾因沙姆斯大学NICU和儿科外科进行,纳入有GERD症状和体征的新生儿和2个月以下的婴儿。记录人口统计资料、临床病史、医疗管理、抗反流手术需求和结果。结果:本研究共纳入40例患者,均开始接受药物治疗。在医疗管理失败或出现危及生命的并发症后,其中12人接受了抗反流手术。在医疗组中,6例患者出现主要并发症(支气管肺发育不良和败血症),4例死亡。在手术组中,记录了3例与术前长时间通气导致支气管肺发育不良相关的死亡。手术干预的需要与胎龄较小(p = 0.001)、分娩时年龄较小(p = 0.006)和分娩时体重较轻(p = 0.034)显著相关。结论:用药超过35天疗效不理想、低出生体重、胎龄(≤32周)、出生后10天入住新生儿重症监护病房是进行新生儿早期抗反流手术的高危因素。
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引用次数: 1
Coblator assisted marsupialization of vallecular cyst 裂囊器辅助小静脉囊肿有袋化术
Q4 Medicine Pub Date : 2022-06-14 DOI: 10.47338/jns.v11.1066
Pradeep Kumar, Lakshmi Venkitaraman
The lesion was misdiagnosed elsewhere as laryngomalacia and spontaneous recovery were assured without intervention. Endoscopic evaluation was not done. The baby was brought to our center due to failure to thrive, feeding difficulty, repeated choking episodes, and worsening physical findings. Preoperative fiber optic laryngoscopy was done which revealed a cystic lesion at the vallecula obstructing the laryngeal inlet, pushing the epiglottis forward (Fig. 2). MRI scan showed a well-defined nonenhancing thin-walled cystic lesion measuring 14.8x14.2mm at vallecula and the diagnosis was confirmed (Fig. 3). Surgery was planned. Intubation was attempted but failed. The baby was tracheostomized before the procedure for ventilation, anticipating postoperative surgical site edema as well. Uncuffed tracheostomy tube size 3 was used. A direct laryngoscope straight blade with zero degree endoscope was held by the anesthetist to view the cyst and the EVAC-70 coblation wand was held in the right hand by the surgeon. The settings of the coblator were maintained at 70-30, coblation and coagulation respectively. The wand was used in both coblator and coagulation mode based on need. The anterior cyst wall was completely removed by coblation, and the cyst was thus marsupialized.
该病变在其他地方被误诊为喉软化症,无需干预即可自行恢复。未进行内镜评估。由于发育不良、喂养困难、反复窒息和身体状况恶化,婴儿被带到我们的中心。术前进行了纤维喉镜检查,结果显示vallecula有一个囊性病变,阻塞了喉部入口,将会厌向前推进(图2)。MRI扫描显示vallecula处有一个明确的非强化薄壁囊性病变,尺寸为14.8x14.2mm,诊断得到证实(图3)。手术是有计划的。尝试插管,但失败。婴儿在手术前进行了气管造口通气,预计术后手术部位也会出现水肿。使用3号无衬垫气管造口管。麻醉师拿着带零度内窥镜的直接喉镜直片来观察囊肿,外科医生拿着EVAC-70插管棒在右手。钴床的设置分别保持在70-30、钴化和凝固。根据需要,该棒可用于除钴和凝固模式。囊肿前壁被钴化完全去除,囊肿因此被有袋化。
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引用次数: 0
Neonatal abdominal cocoon arising from atypical sequelae of intestinal malrotation: A case report 新生儿腹部茧引起的不典型后遗症肠旋转不良:1例报告
Q4 Medicine Pub Date : 2022-06-07 DOI: 10.47338/jns.v11.1057
L. Abdur-Rahman, OA Ojajuni, TK Raji
Background: Abdominal cocoon (AC) is the partial or complete encasement of the intestines and sometimes other abdominal organs by a fibro-collagenous sac causing varied presentations of intestinal obstruction. It has been found in all age groups from neonates to the elderly although neonatal AC is quite rare and only very few cases have been reported. In neonates, the presentation could mimic other causes of partial or complete intestinal obstruction and preoperative diagnosis is usually difficult.Case Presentation: We report an atypical sequela of intestinal malrotation causing neonatal intestinal obstruction due to omental encasement of the small and large bowel. The diagnosis was made intraoperatively though contrast gastrointestinal series suggested the partial obstruction at the duodenal-jejunal level. The patient made a good postoperative recovery after extraction of the bowel from the cocoon (omental sac), partial omentectomy, and Ladd’s procedure.Conclusion: A neonatal abdominal cocoon caused by an omental encasement in a malrotated intestine is a unique presentation and a rare cause of neonatal intestinal obstruction.
背景:腹茧(AC)是由纤维胶原囊部分或完全包裹肠道,有时包裹其他腹部器官,导致各种肠梗阻表现。从新生儿到老年人,所有年龄组都有发现,尽管新生儿AC非常罕见,而且只有极少数病例报告。新生儿的表现可能与部分或完全性肠梗阻的其他原因相似,术前诊断通常很困难。病例介绍:我们报告了一种非典型的肠旋转不良后遗症,由于小肠和大肠的网膜包裹导致新生儿肠梗阻。诊断是在手术中作出的,尽管胃肠道造影系列显示十二指肠空肠部分梗阻。患者在从茧中取出肠管(网膜囊)、部分网膜切除术和Ladd手术后恢复良好。结论:由旋转不良的肠内网膜包裹引起的新生儿腹部茧是新生儿肠梗阻的一种独特表现,也是一种罕见的原因。
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引用次数: 0
Pulmonary lymphangiectasia a rare cause of chylothorax: A case report 肺淋巴管扩张是乳糜胸的一种罕见病因
Q4 Medicine Pub Date : 2022-04-10 DOI: 10.47338/jns.v11.1037
J. Conner, R. Mahon, J. Camps
Background: Pulmonary lymphangiectasia (PL) is a rare disease characterized by dilation of the pulmonary lymphatic vessels. PL should be considered in the differential diagnosis in infants with pleural effusion, especially in the presence of chylothorax.Case Presentation: A 3-week-old neonate presented with tachypnea, cough, and reluctance to feed. Work-up found bilateral chylous pleural effusion. The patient was initially managed conservatively with bilateral tube thoracostomies and octreotide, however output from chest tubes did not subside. A left thoracotomy was performed with wedge biopsy of the apical segment of the left inferior lung lobe and multiple titanium clips were used to control thoracic duct. Postoperatively the patient continued to have high chest tube output, despite placement of clips. Histology of the biopsy confirmed the diagnosis of congenital pulmonary lymphangiectasia.Conclusion: Pulmonary lymphangiectasia is a rare cause of chylothorax. The treatment is often challenging as found in the index case.
背景:肺淋巴管扩张症(PL)是一种罕见的以肺淋巴管膨胀为特征的疾病。在鉴别诊断婴儿胸腔积液时,应考虑PL,尤其是在有乳糜胸的情况下。病例介绍:一名3周大的新生儿出现呼吸急促、咳嗽和不愿进食。复查发现双侧乳糜性胸腔积液。患者最初采用双侧胸腔管造口术和奥曲肽保守治疗,但胸腔管的输出量没有下降。左胸切开术对左下肺叶心尖段进行楔形活检,并使用多个钛夹控制胸导管。术后,尽管放置了夹子,但患者的胸管输出量仍然很高。活检组织学证实诊断为先天性肺淋巴管扩张症。结论:肺淋巴管扩张是乳糜胸的一种罕见病因。正如在指数病例中发现的那样,治疗通常具有挑战性。
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引用次数: 0
Functional Intestinal Obstruction of Prematurity (FIOP): Short term management results: A case series 早产儿功能性肠梗阻(FIOP):短期管理结果:一个病例系列
Q4 Medicine Pub Date : 2022-03-29 DOI: 10.47338/jns.v11.1048
D. Acosta Farina, Verónica Polit-Guerrero, Johan Aguayo-Vistin, Cristhian Cedeño-Moreira, Vicente Salinas-Salinas, Daniel Acosta-Bowen, J. Oliveros-Rivero
Background: Functional Intestinal Obstruction of Prematurity (FIOP) is the delay or failure of meconium evacuation in premature neonates. It is associated with hypomotility in the developing intestine. It mostly presents with signs of intestinal obstruction in very low (VLBW) or extremely low birth weight (ELBW) neonates.Case Series: We present short-term results regarding the management of 8 premature newborns with FIOP treated with Awolaran O. et al [1] algorithm in a pediatric hospital, two of them required a surgical procedure due to conservative management failure.Conclusion: Early conservative management is successful in most patients with FIOP, related to symptom resolution. Surgical management should be kept for those with conservative management failure.
背景:功能性早产肠梗阻(FIOP)是早产儿胎粪排出的延迟或失败。它与发育中的肠道运动能力低下有关。它主要表现为极低(VLBW)或极低出生体重(ELBW)新生儿的肠梗阻迹象。病例系列:我们介绍了在一家儿科医院用Aworan O.等人[1]算法治疗8例FIOP早产儿的短期结果,其中两例因保守治疗失败而需要手术治疗。结论:大多数FIOP患者早期保守治疗是成功的,这与症状的缓解有关。保守治疗失败者应保留手术治疗。
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引用次数: 0
The 30-day outcome of neonates operated for esophageal atresia 新生儿食管闭锁手术30天疗效观察
Q4 Medicine Pub Date : 2022-03-17 DOI: 10.47338/jns.v11.1049
C. de Vos, L. van Wyk, D. Sidler, P. Goussard
Background: Despite great advances in the overall management of neonates with esophageal atresia (EA), many complications leading to morbidity still occurs.  Most complications can be treated conservatively, but effective management is needed to reduce long-term morbidity. Methods: A retrospective cohort study was performed on neonates treated for EA with/without a tracheoesophageal fistula (TEF) between 2001 and 2020.  Data were collected from patient records, discharge summaries, and surgical notes.  The information recorded included: maternal and neonatal demographics, information regarding the diagnosis, and details surrounding the surgery.Results: During the 19-year study period, 53 neonates with a mean gestational age of 36.7 weeks were included for analysis.  Forty-nine percent presented with an associated anomaly (most commonly, complex cardiac lesions).  The majority (83%) had a primary repair on a median of day 3 of life.  Nineteen neonates had a surgical complication 30 days post-repair: 7 minor (contained leaks and a chylothorax) and 12 major complications including anastomotic strictures, major anastomotic breakdowns, a recurrent TEF, and 5 surgery-related mortalities.Conclusions: This study showed less morbidity and mortality of neonates born with EA, despite a high incidence of associated anomalies, in a resource-restricted hospital.  It is important to highlight that even with limited resources, centers in low- or middle-income countries can have good outcomes.
背景:尽管新生儿食管闭锁(EA)的整体治疗取得了很大进展,但仍有许多并发症导致发病率。大多数并发症可以保守治疗,但需要有效的管理,以减少长期发病率。方法:回顾性队列研究对2001年至2020年期间患有/不患有气管食管瘘(TEF)的新生儿进行了回顾性队列研究。数据收集自患者记录、出院总结和手术记录。记录的信息包括:产妇和新生儿的人口统计资料,有关诊断的信息,以及手术周围的细节。结果:在19年的研究期间,53例平均胎龄36.7周的新生儿被纳入分析。49%表现为相关异常(最常见的是复杂的心脏病变)。大多数患者(83%)在生命的第3天进行了一次修复。19例新生儿在修复后30天出现手术并发症:7例轻微并发症(包含瘘和乳糜胸),12例主要并发症包括吻合口狭窄、吻合口破裂、复发性TEF和5例手术相关死亡。结论:本研究显示,在资源有限的医院中,尽管EA相关异常的发生率很高,但EA新生儿的发病率和死亡率较低。必须强调的是,即使资源有限,低收入或中等收入国家的中心也能取得良好的成果。
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引用次数: 0
Muscle-sparing posterolateral thoracotomy for esophageal atresia Vogt Type 3b 保留肌肉的后外侧开胸术治疗Vogt 3b型食管闭锁
Q4 Medicine Pub Date : 2022-03-11 DOI: 10.47338/jns.v11.1074
Rahul Gupta
Background: Posterolateral muscle cutting thoracotomy is the gold standard approach to repair esophageal atresia with distal tracheoesophageal fistula. This technique is associated with morbidities in terms of poor motor and aesthetic outcomes. We aim to share our experience with muscle-sparing skin crease incision posterolateral thoracotomy for esophageal atresia Vogt type 3b. Methods: It was a retrospective observational study conducted over a period of 3 years and 6 months from January 2016 to June 2019 at two tertiary care teaching institutes. All patients with esophageal atresia having distal tracheoesophageal fistula were included. Results: Fifty-nine neonates underwent muscle-sparing thoracotomy, with 23 males and 36 females. The 34 (58%) neonates had low birth weight. Anorectal malformation (ARM) was the most common (6) associated major malformation(18). Intraoperative findings included long gap EA (6), right aortic arch (RAA, 3), aberrant vessels (1), and long upper pouch (1). Conversion to muscle cutting approach (during early learning curve) was performed in 8 cases i.e. long gap EA (3), RAA (2), Subglottic stenosis (2), others (1). No intraoperative complication was encountered; postoperative seroma formation (related to the approach) was observed in 2 (3.4%) neonates. Most of the patients achieved satisfactory functional and aesthetic outcomes. Conclusions: Muscle-sparing skin crease incision posterolateral thoracotomy is a viable approach for repair of esophageal atresia with distal tracheoesophageal fistula. The technique is easy to perform with adequate exposure and provides satisfactory functional and aesthetic outcomes with relatively minimum morbidity.
背景:后外侧肌切开开胸术是修复食管闭锁伴远端气管食管瘘的金标准方法。这种技术与运动和美学效果不佳的疾病有关。我们的目的是分享我们在保留肌肉的皮肤折痕切口后外侧开胸术治疗Vogt 3b型食管闭锁的经验。方法:这是一项回顾性观察性研究,从2016年1月到2019年6月,在两所三级护理教学机构进行了为期3年零6个月的研究。所有食管闭锁伴远端气管食管瘘的患者均包括在内。结果:59例新生儿接受了保留肌肉开胸术,其中男性23例,女性36例。34名新生儿(58%)的出生体重较低。肛门直肠畸形(ARM)是最常见的(6)相关主要畸形(18)。术中发现包括长间隙EA(6)、右主动脉弓(RAA,3)、异常血管(1)和长上囊(1)。在8例病例中,即长间隙EA(3)、RAA(2)、声门下狭窄(2)和其他(1),进行了肌肉切割方法的转换(在早期学习曲线期间)。未发现术中并发症;在2例(3.4%)新生儿中观察到术后血清瘤形成(与入路有关)。大多数患者获得了令人满意的功能和美学结果。结论:保肌皮褶切口后外侧开胸术是治疗食管闭锁伴远端气管食管瘘的可行方法。该技术易于在充分暴露的情况下进行,并以相对最低的发病率提供令人满意的功能和美学结果。
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引用次数: 0
期刊
Journal of Neonatal Surgery
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