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Cerebral Toxoplasmosis in a Previously Fit Individual – Pitfalls in Management – A Case Report. 先前健康个体的脑弓形虫病-管理陷阱-一例报告。
Pub Date : 2023-03-15 DOI: 10.18502/crcp.v7i6.12273
Norly Salleh, Rusli Zaim, Siti Rodiah Udin
Most people with toxoplasmosis infection are asymptomatic. Cerebral toxoplasmosis in HIV patient represents poor prognostic determinant, but treatable if early treatment is initiated. A case of delayed diagnosis of cerebral toxoplasmosis is presented. A 27-year-old man presented with one-sided facial numbness and treated as Bell’s Palsy. Later he developed slurred speech. Contrast enhanced CT brain showed left frontal temporal hypodense lesion, leptomeningeal enhancement and perilesional oedema. Steroid was started. Four days later, he presented with decreased responsiveness. Retroviral was detected and diagnosis changed to opportunistic brain infection. He died after 3 days. Toxoplasmosis IgG antibodies turned out positive. In diagnosing cerebral toxoplasmosis, clinical presentation and examination are as important as laboratory testing and radiological imaging.
大多数弓形虫感染者没有症状。HIV患者的脑弓形虫病是预后较差的决定因素,但如果早期治疗,可以治疗。本文报告一例迟发性脑弓形虫病诊断。一名27岁的男子出现单侧面部麻木,并接受贝尔麻痹症治疗。后来他变得口齿不清。脑增强CT显示左额颞叶低密度病变、软脑膜增强和病灶周围水肿。类固醇开始使用。四天后,他的反应能力下降。检测到逆转录病毒,诊断为机会性脑感染。3天后他去世了。弓形虫IgG抗体呈阳性。在诊断脑弓形虫病时,临床表现和检查与实验室检查和放射学成像一样重要。
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引用次数: 0
Management and Outcomes of Wilson Disease in Pregnancy: A Case Report 妊娠期Wilson病的治疗和转归:一例报告
Pub Date : 2023-03-15 DOI: 10.18502/crcp.v7i6.12274
Zahra Moaazeni, D. Soltani, M. Rezazadeh, Mohammad Reza Rouhbakhsh Zahmatkesh, Neda Davaryari
Pregnancy in a woman with Wilson disease (WD) can cause pre-eclampsia, miscarriage, and preterm labor and causes hepatic, neurologic, and hematologic complications aside from pregnancy-related difficulties. A 30-year-old female was brought to the emergency room (ER) in her 38th gestational week (GW) with the chief complaint of left foot swelling and weight gain. Aside from a platelet count of about 73000, the rest of the assessment and findings were normal. Regarding the reassurance of the platelet count and holding the medical treatment, throughout the vaginal delivery, a child with Apgar of 9-10 was delivered. WD in pregnancy tends to have complications, thus patient management and how the patient is treated are critical.
患有威尔逊病(WD)的妇女妊娠可引起先兆子痫、流产和早产,并引起肝脏、神经系统和血液系统并发症,除了妊娠相关的困难。一位30岁的女性在她妊娠38周(GW)被带到急诊室(ER),主诉是左脚肿胀和体重增加。除了血小板计数约73000外,其他评估和检查结果均正常。在保证血小板计数和坚持治疗的情况下,在阴道分娩的整个过程中,分娩了一名Apgar为9-10的儿童。妊娠期WD容易出现并发症,因此患者的管理和治疗方法至关重要。
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引用次数: 0
Unusual Abscess Caused by Brucella Melitensis 由梅利特布鲁氏菌引起的异常脓肿
Pub Date : 2023-03-15 DOI: 10.18502/crcp.v7i6.12267
N. Eftekhari, Amir Hossein Mohammad Bagheri
Brucellosis is a zoonotic infectious disease which any organ can be involved. Soft tissue lesions are rare manifestations of brucellosis. Brucella breast abscess in animal is not uncommon; involvement of the breast in human brucella is extremely rare. Breast abscess involvement was reported to 0.7% of the patient with brucellosis. We report the microbiological findings of breast abscess due to brucella. A 38-year-old woman living in the rural area of Kerman, Iran, presented with an abscess in the right breast. The sampling of the abscess aspiration and preparation of smears showed inflammatory fluid. Culture and PCR performed from the sample identified the presence of Brucella melitensis. The lesion had diminished in size after 8 weeks of treatment with combined doxycycline and rifampin. The possibility of breast abscess being caused by Brucella should be considered in countries, especially in endemic regions. Besides, isolated Brucella spp from microbiological cultures is important for a definitive diagnosis.
布鲁氏菌病是一种人畜共患传染病,任何器官都可能感染。软组织病变是布鲁氏菌病的罕见表现。布鲁氏菌乳房脓肿在动物身上并不罕见;人类布鲁氏菌的乳腺受累极为罕见。据报道,0.7%的布鲁氏菌病患者有乳腺脓肿受累。我们报告了布鲁氏菌引起的乳腺脓肿的微生物学检查结果。一名居住在伊朗克尔曼农村地区的38岁妇女出现右乳房脓肿。脓肿抽吸取样和涂片制备显示有炎性液体。从样品中进行的培养和PCR鉴定出存在布鲁氏菌。经多西环素和利福平联合治疗8周后,病变面积缩小。布鲁氏菌引起乳腺脓肿的可能性应在各国考虑,尤其是在流行地区。此外,从微生物培养物中分离出布鲁氏菌对最终诊断很重要。
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引用次数: 0
Trigeminal Neuralgia as a Manifestation of Increased Intracranial Pressure: A Case Report 三叉神经痛是颅内压增高的表现:1例报告
Pub Date : 2023-02-06 DOI: 10.18502/crcp.v7i5.11866
Kiana Amani, S. Ghafouri, B. Pourghaz, A. Tafakhori
The present case report describes a patient who had presented with resistant trigeminal neuralgia and was later discovered to suffer from idiopathic increased intracranial pressure. The related symptoms were resolved by decreasing the intracranial pressure. As in our case, symptom relief can predict a good prognosis in these cases, resulting in an improved quality of life. Although it is not frequently reported, this potential association can be significant as resolving intracranial hypertension can easily improve the symptoms in those suffering from this condition. To our knowledge, no relationship between increased intracranial pressure and trigeminal neuralgia had yet been reported in the literature.
本病例报告描述了一个病人谁曾提出抵抗三叉神经痛,后来发现遭受特发性颅内压升高。通过降低颅内压,相关症状得以缓解。在我们的病例中,症状的缓解预示着这些病例的预后良好,从而改善了生活质量。虽然不经常报道,但这种潜在的关联可能是重要的,因为解决颅内高压可以很容易地改善患有这种疾病的患者的症状。据我们所知,文献中尚未报道颅内压升高与三叉神经痛之间的关系。
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引用次数: 1
When Tuberculosis Co-Presenting with COVID-19 Becomes a Challenge, Case Report and Short Review 当结核病与COVID-19共同呈现成为挑战时,病例报告和简短回顾
Pub Date : 2023-02-06 DOI: 10.18502/crcp.v7i5.11861
Tan Ching Yee, Yee Szemen, Alvin Wang Dingyuan, Foo Rui Min
With current SARS-CoV-2 pandemic, patients with respiratory symptoms are diagnosed with SARS-CoV-2 more readily, but we may oversee some prevalent infective diseases that may co-exist. We report a case of SARS-CoV-2/tuberculosis co-infection and the importance of considering tuberculosis amidst SARS-CoV-2 pandemic.
在当前的严重急性呼吸系统综合征冠状病毒2型大流行中,有呼吸道症状的患者更容易被诊断为严重急性呼吸系综合征冠状病毒,但我们可能会监督一些可能共存的流行感染性疾病。我们报告了一例严重急性呼吸系统综合征冠状病毒2型/结核病合并感染病例,以及在严重急性呼吸系综合征冠状病毒2中考虑结核病的重要性。
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引用次数: 0
Non-Neoformans Pulmonary Cryptococcosis Due to Cryptococcus Laurentii in a Positive SARS-COV-2 Patient 一例SARS-COV-2阳性患者由劳伦隐球菌引起的非新生肺隐球菌病
Pub Date : 2023-02-06 DOI: 10.18502/crcp.v7i5.11859
Priscilla Duran Luciano
Non-neoformans Cryptococcus species were formerly considered to be saprophytes and nonpathogenic to humans [1-2]. However, the incidence of Cryptococcus laurentii infections in immunocompromised and immunocompetent patients has been gradually increasing over the last decades [1-2]. During the COVID-19 pandemic, multiple cases of opportunistic bacterial and fungal infections have been reported in patients after a severe SARS-CoV-2 infection. The author reports the first case of opportunistic pulmonary cryptococcosis caused by Cryptococcus laurentii in a severely ill COVID-19 patient who received treatment with Tocilizumab and dexamethasone. This case contributes to the expanding knowledge of emergent secondary infectious complications including opportunistic pathogens after a SARS-COV-2 infection.
非新生隐球菌以前被认为是腐生植物,对人类无致病性[1-2]。然而,在过去的几十年里,免疫功能低下和免疫功能正常的患者中劳伦隐球菌感染的发病率逐渐增加[1-2]。在COVID-19大流行期间,在严重的SARS-CoV-2感染患者中报告了多例机会性细菌和真菌感染病例。作者报告了一例接受托珠单抗和地塞米松治疗的重症COVID-19患者中由劳伦隐球菌引起的机会性肺隐球菌病。该病例有助于扩大对SARS-COV-2感染后出现的继发性感染并发症(包括机会性病原体)的认识。
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引用次数: 1
A case Report of Simultaneous Subacute Thyroiditis and COVID-19 Infection. A Rare Presentation or Mere Coincidence? 亚急性甲状腺炎合并COVID-19感染1例报告。罕见的表现还是巧合?
Pub Date : 2023-02-06 DOI: 10.18502/crcp.v7i5.11873
S. Samadi, M. Salehi, Hamidreza Emadi, Z. Saffarian, M. Eslami
Subacute thyroiditis is an uncommon thyroid disease which usually occurs after a viral infection. During COVID-19 pandemics, several subacute thyroiditis cases were identified during or after COVID-19. Due to their similar manifestations and high prevalence of COVID-19, subacute thyroiditis might be neglected if the clinicians do not keep it in mind. In this care report, we present a missing patient with SARS-COV-2 infection and subacute thyroiditis which was not suspected until the latent phase of the disease. The patient report can be a re-emphasis on the importance of clinical examination and especially paying attention to palpation of the thyroid gland.
亚急性甲状腺炎是一种罕见的甲状腺疾病,通常发生在病毒感染后。在COVID-19大流行期间,在COVID-19期间或之后发现了几例亚急性甲状腺炎病例。由于亚急性甲状腺炎的表现相似,且COVID-19的患病率较高,如果临床医生不注意,亚急性甲状腺炎可能会被忽视。在这篇护理报告中,我们报告了一名失踪的SARS-COV-2感染和亚急性甲状腺炎患者,直到疾病的潜伏期才怀疑。患者报告可以再次强调临床检查的重要性,特别是要注意触诊甲状腺。
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引用次数: 0
Esophageal-Pleural Fistula: the Cause or Effect of Recurrent Pneumonia? 食管胸膜瘘:复发性肺炎的原因或影响?
Pub Date : 2023-02-06 DOI: 10.18502/crcp.v7i5.11865
H. Asadzadeh Aghdaei, A. Sadeghi, G. Nouri, N. Salarieh, Pardis Ketabi Moghadam
Esophageal-pleural (E-P) fistula is introduced to be an uncommon clinical finding maybe due to non-specific clinical pointers and vague radiologic clues. In this regard, the main drivers are esophageal traumatization, endoscopic dilation, irradiation and corrosive agent ingestion as well as major underlying esophageal diseases like carcinomas and tuberculosis. The presented case is a 51-year-old man with medical record of recurrent pneumonias resulted in right lobectomy who admitted to the medical institution with a significant empyema leading to chest tube insertion. It should be noted that the presence of food particles in the chest bottle in addition to the history of previous surgery raised suspicion of a post-surgical E-P fistula formation. Attempts were made to find fistula tract and insert an esophageal stent bypassing the fistula opening. However, investigations argued against E-P fistula as an ensuing event after surgery and arose the question that whether E-P fistula would be the cause or effect of pneumonia in the presented case?
食管胸膜瘘是一种罕见的临床表现,可能是由于临床指标不明确和放射学线索不明确。在这方面,主要的驱动因素是食道创伤、内镜扩张、辐射和腐蚀性物质的摄入以及主要的潜在食道疾病,如癌症和结核病。本文报告的病例是一名51岁的男性,有右肺叶切除术后复发性肺炎的病史,因明显的脓胸导致胸管插入而入院。值得注意的是,胸瓶中食物颗粒的存在以及既往手术史增加了术后E-P瘘形成的怀疑。尝试寻找瘘道,并通过瘘口置入食管支架。然而,调查反对将E-P瘘作为手术后的后续事件,并提出了E-P瘘是本病例肺炎的原因还是结果的问题?
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引用次数: 0
Acute Necrotizing Encephalopathy Following Presumed COVID-19 Infection: The First Iranian Report in Children 疑似COVID-19感染后急性坏死性脑病:伊朗首例儿童报告
Pub Date : 2023-02-06 DOI: 10.18502/crcp.v7i5.11862
Meisam Babaei, Susan Hosseini, M. Tavakoli, M. Banaei, M. Bagheri
In the fifth’s SARS-CoV-2 infection peak, although extended vaccination, still there is some reports of neurologic complications of covid-19 in children like adult. Though often we expose to benign neurologic features but sometimes there is unusual clinicoradiologic presentation. Thus, report of uncommon neurologic manifestations can help us to better understand of main pathophysiology in pediatric brain involvement. In this report, we present a five-year- old previously healthy girl that arrive to our hospital with fever, vomiting and loss of consciousness, on lumbar puncture there was mild protein elevation without poleocytosis and nasopharyngeal swap PCR for COVID-19 was positive. Brain imaging 10 hours after admission, revealed findings suggestive of acute necrotizing encephalopa thy (ANE). In spite of extensive brain involvement, after prompt initiation of high dose methylprednisolone and IV immunoglobulin, there was dramatic improvement after 3 months’ follow-up. To our knowledge, this is the first Iranian report and the second report on the world.
在第五个严重急性呼吸系统综合征冠状病毒2型感染高峰,尽管延长了疫苗接种,但仍有一些报告称,新冠肺炎在儿童(如成人)中出现神经并发症。虽然我们经常接触到良性的神经系统特征,但有时也有不寻常的临床病理表现。因此,报告不常见的神经系统表现可以帮助我们更好地了解儿童大脑受累的主要病理生理学。在本报告中,我们介绍了一名五岁以前健康的女孩,她因发烧、呕吐和失去意识而来到我们的医院,腰椎穿刺时出现轻度蛋白质升高,没有脑白细胞增多症,新冠肺炎的鼻咽交换PCR呈阳性。入院后10小时的脑部影像学检查结果提示急性坏死性脑出血(ANE)。尽管有广泛的脑损伤,但在迅速开始大剂量甲基强的松龙和静脉注射免疫球蛋白后,经过3个月的随访,情况有了显著改善。据我们所知,这是伊朗关于世界的第一份报告,也是第二份报告。
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引用次数: 0
Distal Vaginal Atresia Combined with Unicornoate Uterus: A Case Report 阴道远端闭锁合并独角子宫1例
Pub Date : 2023-02-06 DOI: 10.18502/crcp.v7i5.11864
F. Mallah, F. Rajabzadeh, Malahat Ebrahimpour
Congenital absence of the vagina with variable uterine development known as Mullerian agenesis. We presented the case of a patient with distal vagina agenesis with presence of proximal vagina and functioning unicornoate uterus. A 13-year-old patient was referred to pelvic floor service due to primary amenorrhea and pelvic pain. She was diagnosed with the distal vaginal agenesis, functional unicornoate uterus and the ectopic right kidney. Rectoabdominal examination revealed segmental vaginal agenesis and a likely atretic cervix with a huge abdominopelvic mass of about 10 cm in size. On exploratory laparotomy, the bladder was completely dilated and the right kidney was ectopic and both kidneys had moderate hydronephrosis. On the left, a unicorn uterus containing blood and clot, and on the right, a non-functional rudimentary horn with a normal fallopian tube was seen. A neovagina was created by dissection of the space between the urethra hyatus and rectum in laparatomy. It is important to note that the patient may initially present with urinary symptoms and renal signs. Therefore, in the symptoms of urinary tract obstruction, mullerian anomalies should be considered.
先天性阴道缺失,子宫发育不全,称为穆勒氏发育不全。我们介绍了一例远端阴道发育不全的患者,其存在近端阴道和功能正常的独角兽子宫。一名13岁的患者因原发性闭经和骨盆疼痛被转诊至盆底服务。她被诊断为远端阴道发育不全、功能性独角兽子宫和异位右肾。直肠腹部检查显示,阴道节段性发育不全,子宫颈可能闭锁,腹盆腔巨大肿块约10厘米。在剖腹探查中,膀胱完全扩张,右肾异位,两个肾都有中度积水。左边是一个含有血液和凝块的独角兽子宫,右边是一个没有功能的发育不全的角,输卵管正常。在剖腹产术中,通过解剖尿道透明体和直肠之间的空间来制造新阴道。需要注意的是,患者最初可能会出现泌尿系统症状和肾脏体征。因此,在出现尿路梗阻症状时,应考虑穆勒管畸形。
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引用次数: 0
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Case Reports in Clinical Practice
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