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Biliary Ascariasis with Gallbladder Invasion: A Unique Entity 胆道蛔虫病伴胆囊侵袭:一种独特的疾病
Pub Date : 2023-06-28 DOI: 10.18502/crcp.v8i1.13091
Manzoor Hussain, Nargis Banoo
ntestinal Ascariasis is a common helminthic infection in developing countries and in some rare cases, worms migrate to the biliary tract and gall bladder. Extraintestinal biliary ascariasis presents with jaundice, right upper quadrant abdominal pain, and vomiting. Ultrasonography is a useful diagnostic modality. Albendazole and Mebendazole are commonly used anti-helmintic agents for conservative management, whereas endoscopic removal is needed in rare cases.
蛔虫病是发展中国家常见的蠕虫感染,在一些罕见的情况下,蠕虫会迁移到胆道和胆囊。肠外胆道蛔虫病表现为黄疸、右上腹腹痛和呕吐。超声检查是一种有用的诊断方法。阿苯达唑和甲苯达唑是常用的抗蠕虫药物,用于保守治疗,而在极少数情况下需要内镜切除。
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引用次数: 0
Rhino-orbital Mucormycosis in an Immunocompetent Pediatric Patient, Resembling an Orbital Mass- a Case Report 一例具有免疫功能的儿童患者的鼻腔眼眶毛霉菌病,类似眼眶肿块-病例报告
Pub Date : 2023-06-28 DOI: 10.18502/crcp.v8i1.13101
S. M. Rafizadeh, M. Aminizade, F. A. Amoli, M. Anari, M. Khodabandeh, Abbas Mohammadi
Rhino-orbital mucormycosis in an immunocompetent pediatric patient can present as an orbital mass. We report a 9-year-old male that presented with periorbital swelling and limitation of left eye movement from one month ago. The patient was treated at another center with a diagnosis of mucormycosis but was referred due to worsening symptoms. Orbital and paranasal sinus CT scan revealed opacities in the left paranasal sinus and soft tissue density in the medial and inferior orbital wall. The patient underwent orbitotomy and mass debulking surgery on suspicion of a possible neoplastic mass. Pathologic evaluations revealed mucormycosis. After receiving intravenous liposomal amphotericin-B that was followed by oral posaconazole syrup for two months and sinus debridement, the symptoms regressed. In immunocompromised pediatric patients, mucormycosis should be considered in the differential diagnosis of an orbital mass.
鼻-眼眶毛霉菌病在免疫功能正常的儿科患者可以表现为眼眶肿块。我们报告一个9岁的男性,从一个月前出现眼眶周围肿胀和左眼运动受限。患者曾在另一中心治疗,诊断为毛霉病,但因症状恶化而转诊。眼眶及鼻窦CT显示左侧鼻窦混浊,眶内及下壁软组织密度大。病人因怀疑可能有肿瘤肿块而接受眼窝切开及肿块减积手术。病理检查显示为毛霉病。经静脉滴注两性霉素- b脂质体,口服泊沙康唑糖浆2个月,鼻窦清创后症状消退。在免疫功能低下的儿童患者中,在眼眶肿块的鉴别诊断中应考虑毛霉菌病。
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引用次数: 0
a Case of COVID-19 with No Pulmonary Involvement; but with Mediastinal and Subcutaneous Emphysema 一例无肺部受累的新冠肺炎病例;但伴有纵隔和皮下肺气肿
Pub Date : 2023-03-15 DOI: 10.18502/crcp.v7i6.12272
Hamid Talebzadeh, Sadegh Mazaheri-Tehrani, Mohammad Fakhrolmobasheri
Spontaneous pneumomediastinum (SPM) is a rare clinical entity. In the normal population, it is more likely to occur in people with conditions including chronic obstructive pulmonary diseases and asthma. In the context of COVID-19 few cases of SPM have been reported which most of them were patients with severe lung parenchymal inflammation or patients under mechanical ventilation. In this case, we report a young male with a history of minor childhood asthma who presented with acute dyspnea, forceful coughs, and subcutaneous emphysema. Chest computed tomography had no clues for COVID-19, however, pneumomediastinum and subcutaneous emphysema were obvious. He was primarily diagnosed with acute asthma exacerbation causing SPM but eventually, he tested positive for SARS-COV-2, therefore, he underwent the standard treatment for COVID-19 and the SPM was managed conservatively. Finally, after 12 days of hospitalization, he was discharged in favorable clinical condition.
自发性纵隔气肿(SPM)是一种罕见的临床疾病。在正常人群中,它更可能发生在患有慢性阻塞性肺病和哮喘等疾病的人群中。在新冠肺炎背景下,SPM病例报道较少,多为重度肺实质炎症患者或机械通气患者。在这个病例中,我们报告了一个有轻微儿童哮喘史的年轻男性,他表现为急性呼吸困难,强烈咳嗽和皮下肺气肿。胸部ct未见新冠肺炎线索,纵隔气肿、皮下肺气肿明显。他最初被诊断为急性哮喘加重,导致SPM,但最终,他的SARS-COV-2检测呈阳性,因此,他接受了COVID-19的标准治疗,SPM得到了保守治疗。最终住院12天后出院,临床情况良好。
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引用次数: 0
Tuberculous Arthritis: A Forgotten Diagnosis During Pandemic Covid-19 结核性关节炎:新冠肺炎大流行期间被遗忘的诊断
Pub Date : 2023-03-15 DOI: 10.18502/crcp.v7i6.12268
T. Huwae, A. Pribadi
Tuberculosis (TB) is a respiratory disease that primarily affects the lungs. The challenge is to recognize the characteristic of TB disease, including extrapulmonary presentation. TB arthritis is an extrapulmonary TB presentation in the joint, which is frequently neglected and misdiagnosed. A 41-year-old female patient was presented with a major complaint of chronic pain in her left wrist for three months. The patient had a low-grade fever without respiratory symptoms. Local examination revealed swelling, warmth and tenderness. Erythrocyte sedimentation rate (ESR) was increased and chest radiograph demonstrated pulmonary TB. She underwent arthrotomy debridement and culture examination. We initiated adjuvant anti-tuberculous treatment. On the evaluation, she reported relief from pain and showed improvement in general condition. TB arthritis is unique due to its rare incidence and unspecific clinical manifestations. A better understanding of these issues will prevent possible diagnostic errors. Prompt treatment was crucial to maintain joint function and prevent permanent destruction.
结核病是一种主要影响肺部的呼吸系统疾病。挑战在于认识结核病的特征,包括肺外表现。结核性关节炎是肺外结核在关节的表现,它经常被忽视和误诊。一位41岁的女性患者以左手腕慢性疼痛三个月为主诉。病人有低烧,无呼吸道症状。局部检查显示肿胀、发热和压痛。红细胞沉降率(ESR)升高,胸片显示为肺结核。行关节切开术、清创及培养检查。我们开始辅助抗结核治疗。在评估中,她报告疼痛减轻,一般情况有所改善。结核性关节炎的独特之处在于其罕见的发病率和非特异性的临床表现。更好地理解这些问题将防止可能出现的诊断错误。及时治疗对于维持关节功能和防止永久性损伤至关重要。
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引用次数: 0
Misoprostol is Useful for Post Cesarean Section Management of Redo Syndrome 米索前列醇可用于剖宫产后再造综合征的治疗
Pub Date : 2023-03-15 DOI: 10.18502/crcp.v7i6.12275
A. D. Shahraki, Azam Zafarbakhs, Amirreza Farhadian Dehkordi, Taherh Khalili Brojeni, F. Haghollahi
Redo syndrome or acute hematometra is a rare complication after abortion or cesarean section.A-32- year-old woman with previous cesarean section, term pregnancy, and labor pain referred to hospital.She delivered a healthy baby with a good Apgar score and discharge 2 days later without complications after a cesarean section. She came back to the hospital with the severe abdominal pain, weakness, without abnormal bleeding, at 6 days postpartum. Abdominopelvic sonography showed a large hematometra in the uterus. She took misoprostol 200 μg intra vaginal and 200μg sublingual, plus serum oxytocin and cefazolin. After about 1.5 hours, she passed a large hematoma, her pain gradually relieved, and she was discharged three days later. This report show that misoprostol is useful in the management of acute hematometra.
重做综合征或急性血肿是流产或剖宫产术后罕见的并发症。一名32岁女性,既往剖宫产,足月妊娠,分娩疼痛转至医院。她生下了一个健康的婴儿,Apgar评分良好,并在剖宫产术后2天后出院,无并发症。产后6天,患者腹痛剧烈,身体虚弱,未见异常出血。盆腔超声显示子宫内有大量血肿。米索前列醇阴道内200μg,舌下200μg,加血清催产素和头孢唑林。约1.5小时后,患者大血肿排出,疼痛逐渐缓解,3天后出院。本报告显示米索前列醇在急性血肿治疗中是有用的。
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引用次数: 0
Familial Neuromyelitis Optica: A Case Report and Literature Review 家族性视神经脊髓炎1例报告及文献复习
Pub Date : 2023-03-15 DOI: 10.18502/crcp.v7i6.12276
Z. Ebadi, F. Ghadiri, E. Asadollahzade, A. Moghadasi
Neuromyelitis Optica Spectrum Disorder (NMOSD) is an autoimmune rare disorder that involves the endfeet of astrocytes. The role of genetics in the disease is not well known. Rare cases of familial NMOSD were reported worldwide. In this report, first, we presented a young man with myelitis and his cousin who suffered from this disease. Then we reviewed some reports around the world about familial NMO. The prevalence of familial NMO is nearly 3%. First cases are reported from East Asia. Its characteristics are similar to the sporadic type. Recent data suggest genetics play role in NMO.
视神经脊髓炎谱系障碍(NMOSD)是一种涉及星形胶质细胞末端的自身免疫性罕见疾病。遗传学在这种疾病中的作用尚不清楚。家族性NMOSD的罕见病例在世界范围内均有报道。在这份报告中,首先,我们介绍了一名患有脊髓炎的年轻人和他的堂兄,他们患有这种疾病。然后,我们回顾了世界各地关于家族性NMO的一些报道。家族性NMO的患病率接近3%。东亚报告了首例病例。其特征与散发型相似。最近的数据表明遗传学在NMO中起作用。
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引用次数: 0
a Case of COVID-19 and Tuberculous Meningitis Coinfection 新冠肺炎并发结核性脑膜炎1例
Pub Date : 2023-03-15 DOI: 10.18502/crcp.v7i6.12269
Shaghayegh Ashraf Talesh, Sara Zare, A. Hadadi
Neurological symptoms like headache have been reported in patients infected with tuberculosis (TB) and COVID-19 infection [1]. A high index of suspicions is necessary for diagnosing of COVID-19 and neurologic tuberculous coinfection, particularly in the communities at high risk for TB or in an endemic region. Herein, we report a case of a 60-year-old man diagnosed with acute COVID-19 and tuberculous meningitis coinfection, to emphasize challenges about this coinfection, because underlying lung diseases like latent TB will affect the clinical categorization (for severity) of COVID-19, and then active TB disease may severe illness.
据报道,感染结核病(TB)和新冠肺炎的患者出现头痛等神经系统症状[1]。高怀疑指数对于诊断新冠肺炎和神经结核合并感染是必要的,特别是在结核病高危社区或流行地区。在此,我们报告了一例60岁男性被诊断为急性新冠肺炎和结核性脑膜炎合并感染的病例,以强调这种合并感染的挑战,因为潜在结核病等潜在肺部疾病会影响新冠肺炎的临床分类(严重程度),然后活动性结核病可能会导致严重疾病。
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引用次数: 0
Rhino-Sino-Cerebral Mucormycosis Associated with Long-Term Rituximab Therapy in Multiple Sclerosis: A Case Report and Review of the Literature 多发性硬化症长期利妥昔单抗治疗相关的鼻-脑毛霉菌病:1例报告和文献回顾
Pub Date : 2023-03-15 DOI: 10.18502/crcp.v7i6.12278
Mohsen Koosha, Golfam Mehrparvar, Sepideh Paybast
Introduction: Rituximab is a CD20 depleting agent, widely used as an off-label diseasemodifying treatment (DMT) in treating multiple sclerosis (MS). The present study aimed to report the first case of rhino-sino-cerebral mucormycosis in a patient with secondary progressive MS (SPMS), treated with rituximab. Case Report: The patient was a 38-year-old man with a history of SPMS treated with rituximab, who developed subacute left vision loss and impaired ocular movement. He also mentioned a concomitant severe headache and cheek swelling. Based on the brain and orbital magnetic resonance imaging (MRI) findings, rhino-sino-cerebral mucormycosis was suspected. Subsequent endoscopic examination confirmed the diagnosis. He underwent medical treatment with amphotericin B liposomal and surgical debridement leading to a significant clinical recovery. He was eventually discharged home with a solid recommendation to discontinue rituximab. Conclusion: The present report indicates a case of SPMS treated with rituximab, who developed rhino-sino-cerebral mucormycosis.
简介:利妥昔单抗是一种CD20消耗剂,广泛用作治疗多发性硬化症(MS)的标签外疾病治疗(DMT)。本研究旨在报告第一例用利妥昔单抗治疗的继发性进行性多发性硬化症(SPMS)患者的鼻-大脑毛霉菌病。病例报告:患者是一名38岁的男性,有接受利妥昔单抗治疗的SPMS病史,出现亚急性左视力丧失和眼球运动障碍。他还提到了伴随而来的严重头痛和脸颊肿胀。根据脑部和眼眶磁共振成像(MRI)结果,怀疑为鼻-大脑毛霉菌病。随后的内窥镜检查证实了诊断。他接受了两性霉素B脂质体药物治疗和外科清创术,取得了显著的临床康复。他最终出院回家,得到了停用利妥昔单抗的可靠建议。结论:本报告显示一例经利妥昔单抗治疗的SPMS患者并发鼻-脑毛霉菌病。
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引用次数: 0
Perioperative Management of Patients with Asthma-COPD Overlap Syndrome - Where Do We Stand? A Case Report-Based Discussion 哮喘-慢性阻塞性肺病重叠综合征患者的围手术期管理-我们站在哪里?基于案例报告的讨论
Pub Date : 2023-03-15 DOI: 10.18502/crcp.v7i6.12299
H. R. Reazaul Karim, Chinmay Kumar Panda, Kalyani Manasa Rapeti, Nivedita Jayanti Bodra, Pragadeshwaran Rajendran
Background: Postoperative pulmonary complications (PPCs) are associated with a significant morbidity and mortality; prevention and management strategies depend greatly on the patients’ comorbid conditions. Chronic Obstructive Pulmonary Disease (COPD) is a well-known risk factor for PPCs, but controlled Asthma does not appear to be so. On the other hand, the role of Asthma-COPD Overlap Syndrome (ACOS) as a risk for PPCs is yet to be studied. While there is a guidance for the perioperative risk reduction and management of COPD and Asthma, specific guidance for ACOS is also lacking. As a consequence, physicians tailor their management by considering both the components. Case presentation: We present a case of a 74-year-old man with ACOS, diagnosed with invasive bladder carcinoma. He was taken for laparoscopic radical cystectomy and ileal conduit. Although he had an uneventful surgery, we lost him on the seventh postoperative day due to multiple complications, including PPCs.  Conclusion: The case highlights the need for considering the ACOS separately as a risk and calls for a specific roadmap for perioperative management.   Asthma-COPD Overlap Syndrome patients appear to be at high risk of PPCs There is a lack of evidence-based guidance and literature to tailor the management of such patients to reduce the perioperative risks for PPCs It is high time to delineate the ACOS patients from Asthma and COPD, study them in context to PPCs and perioperative outcome so that specific guidance can be developed.
背景:术后肺部并发症(PPCs)与显著的发病率和死亡率相关;预防和管理策略在很大程度上取决于患者的合并症。慢性阻塞性肺疾病(COPD)是PPCs的一个众所周知的危险因素,但受控哮喘似乎并非如此。另一方面,哮喘-慢阻肺重叠综合征(ACOS)作为PPCs风险的作用尚待研究。虽然有COPD和哮喘围手术期风险降低和管理的指南,但对ACOS的具体指导也缺乏。因此,医生通过考虑这两个组成部分来调整他们的管理。病例介绍:我们报告一例74岁男性ACOS,诊断为浸润性膀胱癌。行腹腔镜根治性膀胱切除术及回肠导管切除术。虽然他进行了一次平安无事的手术,但由于多种并发症,包括PPCs,我们在术后第7天失去了他。结论:该病例强调了将ACOS作为一种风险单独考虑的必要性,并呼吁制定围手术期管理的具体路线图。哮喘-慢阻肺重叠综合征患者是PPCs的高危人群,缺乏循证指导和文献来定制此类患者的管理,以降低PPCs的围手术期风险。将ACOS患者从哮喘和慢阻肺中区分出来,并将其与PPCs和围手术期结局结合起来研究,以便制定具体的指导。
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引用次数: 0
Portal Vein Thrombosis in a Woman with a Large Uterine Fibroma 大子宫纤维瘤并发门静脉血栓1例
Pub Date : 2023-03-15 DOI: 10.18502/crcp.v7i6.12277
F. Almassinokiani, P. Akbari, Alireza Almasi Nokiani, Niloufar Sarchami
This article presents a case of portal vein thrombosis accompanied by a large uterine fibroma. A 37-year-old virgin woman presented with vaginal bleeding, abdominal mass, fever, dyspnea and lower limbs edema. In past medical history, she did not have any systemic diseases. She had menometrorrhagia from four years ago. She was admitted with diagnosis of a large uterine fibroma and was suspected of COVID 19 pneumonia or thrombophlebitis. The final diagnosis was a large uterine fibroma with chronic portal vein thrombosis. Although uterine fibromas are benign tumors, they may make serious life-threatening complications like thrombosis. The cause of thrombosis is the pressure effect of fibroma and/ or transfusion to treat anemia. Although there may be other unknown etiologies for thrombosis in these patients. We suggest that existence of a large uterine myomas should be known as a risk factor for thrombosis ( like IBS, Covid 19 and etc.) and be given a score in Caprini Score system, to start anticoagulation before and after any surgical intervention.
本文报告一例门静脉血栓形成伴巨大子宫纤维瘤。一位37岁的处女女性出现阴道出血、腹部肿块、发烧、呼吸困难和下肢水肿。在过去的病史中,她没有任何系统性疾病。她四年前就有月经过多。她被诊断为大型子宫纤维瘤,疑似新型冠状病毒肺炎或血栓性静脉炎。最终诊断为患有慢性门静脉血栓形成的大型子宫纤维瘤。尽管子宫纤维瘤是良性肿瘤,但它们可能会引起严重的危及生命的并发症,如血栓形成。血栓形成的原因是纤维瘤和/或输血治疗贫血的压力作用。尽管这些患者可能还有其他未知的血栓形成病因。我们建议,大子宫肌瘤的存在应被视为血栓形成的危险因素(如IBS、新冠肺炎19等),并在Caprini评分系统中进行评分,以便在任何手术干预前后开始抗凝。
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引用次数: 0
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Case Reports in Clinical Practice
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