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Atrial flow regulator and atrial septostomy in pediatric pulmonary hypertension: when procedure and device match 心房流量调节剂和房间隔造口术治疗小儿肺动脉高压:当手术和设备匹配时
Q2 Medicine Pub Date : 2023-07-05 DOI: 10.24875/recice.m23000391
Lisa Bianco, A. Sabaté-Rotés, A. Torrent‐Vernetta, and Pedro Betrián-Blasco
a Unidad de Hemodinámica Pediátrica, Hospital Vall d’Hebrón, Universitat Autònoma de Barcelona, Barcelona, Spain b Servicio de Cardiología Pediátrica, Hospital Vall d’ Hebrón, Universitat Autònoma de Barcelona, Barcelona, Spain c Servicio de Alergia Pediátrica, Neumología Pediátrica y Fibrosis Quística, Hospital Vall d’ Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain d Centro de Investigación en Red de Enfermedades Raras (CIBERER), Instituto de Salud Carlos III, Spain Scientific letter
A儿科血流动力学股,Vall d'Hebron医院,巴塞罗那自治大学,巴塞罗那,西班牙B儿科心脏病学服务,Vall d'Hebron医院,巴塞罗那自治大学,巴塞罗那,西班牙C儿科过敏服务,儿科肺病学和囊性纤维化,Vall d'Hebron医院,巴塞罗那自治大学,巴塞罗那,西班牙D罕见疾病网络研究中心(CIBER),卡洛斯三世健康研究所,西班牙科学快报
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引用次数: 0
Use of a pediatric risk score for cardiac catheterization in a Spanish population with congenital heart disease 在西班牙先天性心脏病患者中使用儿童心导管插入术风险评分
Q2 Medicine Pub Date : 2023-07-05 DOI: 10.24875/recice.m23000395
Paulo Éden Santos, F. Ballesteros, Alexandro Rodríguez, and José Luis Zunzunegui
Introduction and objectives: Performing cardiac catheterization can be challenging regarding the management of congenital heart disease. Therefore, the use of risk scoring or grading systems can help us plan the procedure. Back in 2015, the Congenital Cardiac Interventional Study Consortium developed and validated a system called CRISP (Catheterization risk score for pediatrics), which predicted the risk of serious adverse events (SAEs) prior to cardiac catheterization. Our aim was to use and validate the same scoring system to predict SAEs associated with cardiac catheterization in a Spanish pediatric hospital. Methods: A retrospective descriptive study was performed between January 2016 and May 2017. To create the area under the curve, the expected number of events was correlated with the overall number of cases (compared to the original CRISP). Pearson’s chi-square test was used to assess the performance of the scoring system. Results: A total of 516 patients were successfully enrolled, 26.6% of whom were < 1 year-old [range, 1 day to 18 years], 56.5% were males, and 17% weighed < 5 kg. Around 63.3% of the procedures performed were percutaneous compared to 1.2% that were hybrid. A total of 40 SAEs were found to be amenable to immediate correction with no associated mortality. CRISP showed good discrimination with an area under the curve of 0.71 (95%CI, - 0.66-0.91) compared to the original score of 0.74, and adequate goodness of fit with Pearson’s chi-square test of 8.26 ( P < .08). Conclusions: Despite the performance of highly complex procedures, the rate of SAEs was similar to the one previously published. CRISP has proven to be a good benchmarking and risk stratification tool. Therefore, it can be successfully used in the Spanish pediatric population and have a positive impact on patient care like helping during pre-and post-catheterization care planning.
引言和目的:在先天性心脏病的治疗中,进行心导管插入术可能具有挑战性。因此,使用风险评分或分级系统可以帮助我们规划程序。早在2015年,先天性心脏介入研究联合会就开发并验证了一个名为CRISP(儿科导管风险评分)的系统,该系统预测了心导管插入术前发生严重不良事件的风险。我们的目的是在西班牙一家儿科医院使用并验证相同的评分系统来预测与心导管插入术相关的严重不良事件。方法:在2016年1月至2017年5月期间进行回顾性描述性研究。为了创建曲线下的区域,将预期事件数与总病例数相关联(与原始CRISP相比)。皮尔逊卡方检验用于评估评分系统的性能。结果:共有516名患者成功入选,其中26.6%的患者年龄<1岁[范围为1天至18岁],56.5%为男性,17%的患者体重<5公斤。约63.3%的手术是经皮手术,而1.2%是混合手术。共发现40例SAE可立即纠正,且无相关死亡率。CRISP显示出良好的辨别力,曲线下面积为0.71(95%CI,-0.66-0.91),而原始得分为0.74,Pearson卡方检验的拟合优度为8.26(P<.08)。CRISP已被证明是一个很好的基准和风险分层工具。因此,它可以在西班牙儿科人群中成功使用,并对患者护理产生积极影响,如在导管插入术前后的护理计划中提供帮助。
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引用次数: 0
Coronary malperfusion in acute type A aortic dissection 急性A型主动脉夹层冠状动脉灌注不良
Q2 Medicine Pub Date : 2023-06-29 DOI: 10.24875/recice.m23000392
Cristina Morante Perea, Tomás Cantón Rubio, Luis Manuel Hernando Romero, J. B. Buendía Miñano, J. Moreu Burgos, and Luis Rodríguez Padial
, Coronary malperfusion in patients with aortic dissection further worsens prognosis due to compromised myocardial blood flow. The incidence rate of coronary disease goes from 9% to 10% according to various registries. 1,2 Also, it can occur simultaneously at the beginning of dissection, during the patient transfer or in the middle of surgery. The management of these patients is still a matter of discussion. The optimal time of myocardial reperfusion is 90 min, a timeframe that cannot be guaranteed with surgical revascularization associated with aortic valve repair surgery. This is the case of a 65-year-old man. The patient was a smoker with chronic kidney disease who was admitted to our center as a «myocar-dial infarction code» case due to suspected anterior ST-segment elevation acute coronary syndrome. The coronary angiography revealed the presence of a type A aortic dissection with coronary malperfusion due to left main coronary artery (LMCA) occlusion. The patient had reported to his tertiary referral center with a 30-min history of oppressive retrosternal chest pain. Upon arrival at the emergency room, he remained symptomatic and hemody-namically unstable (pale, sweaty,
主动脉夹层患者的冠状动脉灌注不良由于心肌血流受损而进一步恶化预后。根据各种登记,冠心病的发病率从9%到10%不等。1,2此外,它可以同时发生在解剖开始时、患者转移期间或手术中期。这些病人的管理问题仍有待讨论。心肌再灌注的最佳时间是90分钟,这一时间段无法保证与主动脉瓣修复手术相关的手术血运重建。这是一名65岁的男性病例。该患者是一名患有慢性肾脏疾病的吸烟者,因疑似ST段抬高急性冠状动脉综合征而以“心肌梗死代码”病例的身份入住我们的中心。冠状动脉造影显示,由于左冠状动脉主干(LMCA)闭塞,存在a型主动脉夹层和冠状动脉灌注不良。该患者向三级转诊中心报告,有30分钟压迫性胸骨后胸痛病史。到达急诊室后,他仍然有症状,血流动力学不稳定(脸色苍白,出汗,
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引用次数: 0
Doctor, I want a TAVI! Should patients choose the type of aortic valve procedure they want? 医生,我想要一个TAVI!患者应该选择他们想要的主动脉瓣手术类型吗?
Q2 Medicine Pub Date : 2023-06-29 DOI: 10.24875/recice.m23000396
M. Martínez‐Sellés
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引用次数: 0
Debate. Cerebral embolic protection systems in TAVI: there is not enough evidence available 辩论TAVI的脑栓塞保护系统:没有足够的证据
Q2 Medicine Pub Date : 2023-06-21 DOI: 10.24875/recice.m23000384
Pedro Luis Martín Lorenzo
,
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引用次数: 0
Debate. Cerebral embolic protection systems in TAVI: there is some supportive evidence 辩论TAVI的脑栓塞保护系统:有一些支持性证据
Q2 Medicine Pub Date : 2023-06-21 DOI: 10.24875/recice.m23000374
P. Jiménez Quevedo
Answer: Former studies described that, during TAVI, loose debris like arterial wall fragments, thrombi, valve tissue, and foreign bodies often enters the circulation.1 These particles are the aftermath of the device making its way through the aorta towards the aortic annulus, the positioning and displacement of a calcified stenotic valve between the new valve stent and the aortic wall, and further manipulations to optimize results (postdilatation). To this date, numerous studies have been published on the safety and efficacy profile of these cerebral protection devices (CPD). Specifically, 4 randomized clinical trials have been published associated with the SENTINEL (Boston Scientific Corp., United States): MISTRAL-C,2 CLEAN TAVI,3 SENTINEL,4 and PROTECTED TAVR5 we can talk about later on. The MISTRAL-C trial used cerebral magnetic resonance imaging to demonstrate a significant reduction in the number of patients with multiple cerebral lesions (20% vs 0%; P = .03) and less cognitive impairment (4% vs 27%; P = .017). Similarly, the CLEAN TAVI trial also reported fewer novel lesions and of a smaller volume without any differences being reported in the number of clinical events in the group that used CPD. These studies demonstrated fragments being captured in almost in 100% of the cases. Several metanalyses6-13 also confirm these results regarding the number and volume of cerebral lesions described, and even some show lower rates of strokes in the DPC group.10,12,13 Therefore, we not only have the visual in situ demonstration of the particles being captured in the baskets following implantation, but also scientific evidence that CPD are effective capturing fragments released during TAVI that can land in cerebral circulation, thus lowering the number of cerebral lesions found on the magnetic resonance imaging during the procedure. However, whether capturing such particles with the device has a clear clinical benefit for its widespread use is still to be elucidated.
答:以前的研究表明,在TAVI过程中,动脉壁碎片、血栓、瓣膜组织和异物等松散碎片经常进入循环。1这些颗粒是装置穿过主动脉进入主动脉环、钙化狭窄瓣膜在新瓣膜支架和主动脉壁之间定位和移位的结果,以及进一步操作以优化结果(扩张后)。到目前为止,已经发表了许多关于这些大脑保护装置(CPD)的安全性和有效性的研究。具体而言,已经发表了4项与SENTINEL(美国波士顿科学公司)相关的随机临床试验:MISTRAL-C、2个CLEAN TAVI、3个SENTINEL、4和PROTECTED TAVR5,我们稍后可以讨论。MISTRAL-C试验使用脑磁共振成像显示,多发性脑损伤患者数量显著减少(20%对0%;P=0.03),认知障碍较少(4%对27%;P=0.017)。同样,CLEAN TAVI试验也报告了较少的新病变和较小的体积,在使用CPD的组中没有任何临床事件数量的差异。这些研究表明,在几乎100%的病例中,碎片被捕获。一些荟萃分析6-13也证实了这些关于所描述的脑损伤的数量和体积的结果,甚至一些结果显示DPC组的中风率较低。10,12,13因此,我们不仅可以直观地原位演示植入后篮子中捕获的颗粒,而且还有科学证据表明,CPD是有效捕获TAVI过程中释放的碎片,这些碎片可以降落在大脑循环中,从而降低手术过程中磁共振成像中发现的脑损伤数量。然而,用该设备捕获此类颗粒是否具有广泛使用的明显临床益处仍有待阐明。
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引用次数: 0
Provoked exercise desaturation in patients with patent foramen ovale, infrequent or underdiagnosed? 卵圆孔未闭患者的诱发性运动去饱和:罕见还是未确诊?
Q2 Medicine Pub Date : 2023-06-21 DOI: 10.24875/recice.m23000388
V. Juárez Olmos, O. Gonzalez-Fernandez, Alfonso Jurado Román, S. Jiménez Valero, C. Contreras Lorenzo, and Almudena Castro Conde
The patent oval foramen (PFO) is present in nearly 1 out of every 4 people
卵圆孔未闭(PFO)存在于近1 / 4的人
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引用次数: 0
Transfemoral valve-in-MAC implantation due to severe radiation-induced mitral stenosis 严重放射性二尖瓣狭窄MAC植入术中的经股瓣膜
Q2 Medicine Pub Date : 2023-06-20 DOI: 10.24875/recice.m23000377
M. Maeztu, L. Ruiz, Leire Andraka, M. Larman, G. Lasa, and Jesús Roberto Sáez
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引用次数: 0
Impact of ischemic preconditioning on the radial artery vasomotor function 缺血预处理对桡动脉血管舒缩功能的影响
Q2 Medicine Pub Date : 2023-06-08 DOI: 10.24875/recice.m23000382
E. Arroyo-Úcar, B. Ibáñez Cabeza, and Gonzalo Pizarro Sánchez
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引用次数: 0
Unsuspected residual coronary guidewire fragment 未经检查的残余冠状动脉导丝碎片
Q2 Medicine Pub Date : 2023-06-08 DOI: 10.24875/recice.m23000383
F. Hernández Hernández
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引用次数: 0
期刊
REC Interventional Cardiology English Ed
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