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Exploring the authentication of COVID-19 vaccines using Surface-enhanced handheld Raman spectroscopy (SERS) equipped with orbital Raster scattering and machine learning 基于轨道光栅散射和机器学习的表面增强手持拉曼光谱(SERS)技术探索COVID-19疫苗的认证
Pub Date : 2023-01-09 DOI: 10.1109/DeSE58274.2023.10100028
Megan Watson, D. Al-Jumeily, J. Birkett, Iftikhar Khan, S. Assi
COVID-19 is a novel coronavirus first emerging in Wuhan, China in December 2019 and has since spread rapidly across the globe escalating into a worldwide pandemic causing millions of fatalities. Emergency response to the pandemic included social distancing and isolation measures as well as the escalation of vaccination programmes. The most popular COVID-19 vaccines are nucleic acid-based. The vast spread and struggles in containment of the virus has allowed a gap in the market to emerge for counterfeit vaccines. This study investigates the use of handheld Raman spectroscopy as a method for nucleic acid-based vaccine authentication and utilises machine learning analytics to assess the efficacy of the method. Conventional Raman spectroscopy requires a large workspace, is cumbersome and energy consuming, and handheld Raman systems show limitations with regards to sensitivity and sample detection. Surface Enhanced Raman spectroscopy (SERS) however, shows potential as an authentication technique for vaccines, allowing identification of characteristic nucleic acid bands in spectra. SERS showed strong identification potential through Correlation in Wavelength Space (CWS) with all vaccine samples obtaining an r value of approximately 1 when plotted against themselves. Variance was observed between some excipients and a selected number of DNA-based vaccines, possibly attributed to the stability of the SERS colloid where the colloid-vaccine complex had been measured over different time intervals. Further development of the technique would include optimisation of the SERS method, stability studies and more comprehensive analysis and interpretation of a greater sample size.
COVID-19是一种新型冠状病毒,于2019年12月首次在中国武汉出现,此后在全球迅速蔓延,升级为全球大流行,造成数百万人死亡。对大流行的紧急应对措施包括保持社会距离和隔离措施以及扩大疫苗接种规划。最流行的COVID-19疫苗是以核酸为基础的。病毒的广泛传播和控制工作的艰难使得假冒疫苗在市场上出现了空白。本研究调查了手持式拉曼光谱作为基于核酸的疫苗认证方法的使用,并利用机器学习分析来评估该方法的有效性。传统的拉曼光谱需要很大的工作空间,笨重且耗能,手持式拉曼系统在灵敏度和样品检测方面存在局限性。然而,表面增强拉曼光谱(SERS)显示出作为疫苗认证技术的潜力,允许在光谱中识别特征核酸带。SERS通过波长空间相关性(Correlation in Wavelength Space, CWS)显示出很强的识别潜力,所有疫苗样本与自身对比时的r值约为1。在一些赋形剂和一些选定的基于dna的疫苗之间观察到差异,这可能归因于在不同时间间隔测量胶体-疫苗复合物的SERS胶体的稳定性。该技术的进一步发展将包括SERS方法的优化、稳定性研究以及对更大样本量的更全面的分析和解释。
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引用次数: 0
Early Prediction of COVID-19 Infection with IoT and Machine Learning 基于物联网和机器学习的COVID-19感染早期预测
Pub Date : 2023-01-09 DOI: 10.1109/DeSE58274.2023.10099492
Chow Man Pan, Kamalanathan Shanmugam, Muhammad Ehsan Rana, M. Jayabalan
The deadly virus COVID-19 has heavily impacted all countries and brought a dramatic loss of human life. It is an unprecedented scenario and poses an extreme challenge to the healthcare sector. The disruption to society and the economy is devastating, causing millions of people to live in poverty. Most citizens live in exceptional hardship and are exposed to the contagious virus while being vulnerable due to the inaccessibility of quality healthcare services. This study introduces ubiquitous computing as a state-of-the-art method to mitigate the spread of COVID-19 and spare more ICU beds for those truly needed. Ubiquitous computing offers a great solution with the concept of being accessible anywhere and anytime. As COVID-19 is highly complicated and unpredictable, people infected with COVID-19 may be unaware and still live on with their life. This resulted in the spread of COVID-19 being uncontrollable. Therefore, it is essential to identify the COVID-19 infection early, not only because of the mitigation of spread but also for optimal treatment. This way, the concept of wearable sensors to collect health information and use it as an input to feed into machine learning to determine COVID-19 infection or COVID-19 status monitoring is introduced in this study.
新冠肺炎疫情给各国带来严重冲击,造成大量人员伤亡。这是一种前所未有的情况,对医疗保健部门构成了极大的挑战。对社会和经济的破坏是毁灭性的,导致数百万人生活在贫困中。大多数公民生活异常困难,容易感染传染性病毒,同时由于无法获得优质保健服务而易受伤害。这项研究将普适计算作为最先进的方法引入,以减轻COVID-19的传播,并为真正需要的人腾出更多的ICU床位。普适计算提供了一个很好的解决方案,其概念是随时随地都可以访问。由于COVID-19高度复杂和不可预测,感染COVID-19的人可能不知道,仍然继续生活。这导致COVID-19的传播无法控制。因此,及早发现COVID-19感染至关重要,这不仅是为了减缓传播,也是为了获得最佳治疗。通过这种方式,本研究引入了可穿戴传感器的概念,用于收集健康信息并将其作为输入馈送到机器学习中,以确定COVID-19感染或COVID-19状态监测。
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引用次数: 0
“Industrie 4.0” and Smart Manufacturing: A State of the Art Review “工业4.0”与智能制造:最新进展综述
Pub Date : 2023-01-09 DOI: 10.1109/DeSE58274.2023.10100115
A. Hassan, L. Al-Kindi, Amjad Barzan Abdulghafour
Smart Manufacturing is the deployment of big data processing, artificial intelligence, and sophisticated robotics technology, as well as their interconnectedness, to improve manufacturing performance and optimize energy and labor needs. To ensure a new development engine, the industrial sector wants to increase its competitiveness through the convergence of innovative ICT (Information and Communication Technology). Smart Manufacturing represents the Fourth Industrial Revolution and a New Paradigm. It is a set of cutting-edge technologies that facilitate effective and precise engineering decision-making in real time through the introduction of various ICT technologies and their convergence with current manufacturing technologies. This article describes and explores the smart manufacturing system, outlines its present stage of implementation, and discusses its accompanying technologies and their contributions to smart manufacturing technology. Moreover, a survey of the most recent advancements in this field and their effects, as well as the implementation challenges, opportunities, and future directions for smart manufacturing systems, were analyzed and presented in order to realize this rapidly expanding technology and cover all of its dimensions. The purpose of the literature study in this paper is to get a comprehensive understanding of smart manufacturing planning methodologies. Several papers and books produced over the previous five years are evaluated with a focus on the applications and kinds of systems.
智能制造是大数据处理、人工智能和复杂机器人技术的部署,以及它们之间的互联性,以提高制造性能,优化能源和劳动力需求。为了确保新的发展引擎,工业部门希望通过创新ICT(信息和通信技术)的融合来提高竞争力。智能制造代表着第四次工业革命和新范式。它是一套尖端技术,通过引入各种ICT技术及其与当前制造技术的融合,实时促进有效和精确的工程决策。本文对智能制造系统进行了描述和探讨,概述了智能制造系统目前的实施阶段,并讨论了智能制造系统的相关技术及其对智能制造技术的贡献。此外,对该领域的最新进展及其影响,以及智能制造系统的实施挑战,机遇和未来方向的调查进行了分析和介绍,以实现这一快速扩展的技术并涵盖其所有维度。本文文献研究的目的是全面了解智能制造规划方法。在过去的五年里,一些论文和书籍被评估,重点是应用和系统的种类。
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引用次数: 0
A Hybrid Modified ABC-PSO Algorithm for Optimal Robotic Path Planner 机器人最优路径规划的改进ABC-PSO混合算法
Pub Date : 2023-01-09 DOI: 10.1109/DeSE58274.2023.10100021
Nadia I. Khalil, Hadeel N. Abdullah, L. A. Hassnawi
Path planning is one of the most fundamental problems that must be dealt with before the mobile robot can navigate and explore autonomously in any environment. A good path-planning algorithm can save time and reduce mobile robot wear and capital investment. Path computing time and average path length are important factors over cost functions that reflect the algorithm's effectiveness, such as power consumption or average trip time. The Artificial Bee Colony (ABC) represents one of the most important global search algorithms. The main problem with ABC is that it suffers from a slow convergence rate due to lousy exploitation and tends to get trapped in the local minima. This paper proposes and evaluates a new robot path-planning algorithm named Modified Artificial Bee Colony (MABC). MABC algorithm design is based on modifying the ABC algorithm by cross-layer design between ABC and Particle Swarm Optimization (PSO) algorithms. The MABC is different from the original ABC algorithm in that it modifies the original one to use PSO's exploitation rather than its exploitation. On the other hand, the PSO algorithm has better exploitation but poor exploration characteristics. The evaluation and analysis were performed for several performance metrics and under different evaluation scenarios. It has been observed from the results that the MABC-PSO outperforms the original ABC with respect to average path length and convergence time which leads to improving the planning of the path.
路径规划是移动机器人在任何环境中自主导航和探索必须解决的最基本问题之一。一个好的路径规划算法可以节省时间,减少移动机器人的磨损和资金投入。路径计算时间和平均路径长度是反映算法有效性的重要因素,而不是成本函数,如功耗或平均行程时间。人工蜂群(Artificial Bee Colony, ABC)是最重要的全局搜索算法之一。ABC算法的主要问题是,由于糟糕的开发,它的收敛速度很慢,而且容易陷入局部最小值。提出并评价了一种新的机器人路径规划算法——改进人工蜂群(MABC)算法。MABC算法的设计是基于ABC算法与粒子群优化算法(Particle Swarm Optimization, PSO)之间的跨层设计对ABC算法进行改进。MABC算法与原ABC算法的不同之处在于,它对原ABC算法进行了修改,使用了PSO的利用而不是其利用。另一方面,粒子群算法具有较好的开发性,但勘探性较差。对几个性能指标和不同的评估场景进行了评估和分析。从结果中可以看出,MABC-PSO在平均路径长度和收敛时间方面优于原始ABC,从而改进了路径规划。
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引用次数: 0
Preliminary study: Professional Collaboration Application with Project Management Tools 初步研究:项目管理工具的专业协作应用
Pub Date : 2023-01-09 DOI: 10.1109/DeSE58274.2023.10099939
Tam Kai Jun, Sathiapriya Ramiah
This paper studies the understanding and daily need of project management team in the software industry. With the rise in online working environment, the organizations emphasize on daily productivity in the hybrid working mode. To fulfill and solve the market need, Straper is proposed as a project management and collaboration tool to increase daily productivity and reduce the project development cost in the long run. This paper will focus on studying the background of online collaboration that is specific in project management topics. The problem that exists in online collaboration nowadays will be further explored and documented in detail. A total number of 10 literature reviews were conducted by the research in order to explore the domain knowledge and understand the related technology or standard process in-depth. Primary investigations were conducted through questionnaires and interviews to determine and validate the system requirement. Results and analysis show there is still a high value for Straper in the market and able to improve the quality of organization's working mode in the daily basis.
本文研究了软件行业中项目管理团队的认识和日常需求。随着在线工作环境的兴起,组织强调混合工作模式下的日常生产力。为了满足和解决市场需求,Straper被提出作为一个项目管理和协作工具,以提高日常生产力,从长远来看降低项目开发成本。本文将重点研究在线协作的背景,具体到项目管理主题。本文将进一步探讨和详细记录当前在线协作中存在的问题。为了深入挖掘领域知识,了解相关技术或标准流程,本研究共进行了10篇文献综述。通过问卷调查和访谈进行初步调查,以确定和验证系统需求。结果和分析表明,Straper在市场上仍然有很高的价值,并且能够在日常工作中提高组织工作模式的质量。
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引用次数: 0
Automated Face Mask Detection using Artificial Intelligence and Video Surveillance Management 使用人工智能和视频监控管理的自动面罩检测
Pub Date : 2023-01-09 DOI: 10.1109/DeSE58274.2023.10099878
Goh Yih Shien, Kamalanathan Shanmugam, Muhammad Ehsan Rana
Surveillance camera has become an essential, ubiquitous technology in people's daily lives, whether applicable for home surveillance or extended to public workplace detection. The importance of the camera is irreplaceable in terms of the agent for an enclosed system to function correctly. The goal of ubiquitous computing is to keep different devices or technology communicating seamlessly, allowing them to expand to other areas instead of limiting it to one device. However, many research papers have been released on how the camera can aid in the current situation where COVID-19 is still raging worldwide, especially in crowded places. This paper aims to suggest a method by which surveillance cameras on the university campus can automatically detect student face mask status and notify them. Alongside that, this concept of applying a video management system within the university campus will assist in the automation of invigilating the student's daily mask status from the number of embedded surveillance cameras around the campus.
监控摄像机已经成为人们日常生活中必不可少的,无处不在的技术,无论是适用于家庭监控还是扩展到公共工作场所的检测。摄像机的重要性是不可替代的,因为它是一个封闭系统正常运行的代理。泛在计算的目标是保持不同设备或技术的无缝通信,允许它们扩展到其他领域,而不是限制在一个设备上。然而,已经发表了许多关于相机如何在COVID-19仍在全球肆虐的当前情况下提供帮助的研究论文,特别是在拥挤的地方。本文旨在提出一种大学校园监控摄像头自动检测学生口罩状态并通知学生的方法。除此之外,在大学校园内应用视频管理系统的概念将有助于通过校园周围嵌入式监控摄像头的数量来自动化监考学生的日常面具状态。
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引用次数: 0
Vision-Based Fatigue Detection In Drivers Using Multi-Facial Feature Fusion 基于多面部特征融合的驾驶员视觉疲劳检测
Pub Date : 2023-01-09 DOI: 10.1109/DeSE58274.2023.10099741
Sancharee Das, Rupal Bhargava
Fatigued driving has been reported to be a major cause of road accidents claiming millions of lives worldwide. Studies have shown that most road accidents occur either at night or early morning when the driver is already fatigued and there is insufficient light to notice obstacles. Some of the automated fatigue detection systems use physiological signals like EEG, ECG, and blood pressure movements. But, in most cases, the invasive nature of obtaining these signals makes them non-ideal. The recently developed computer vision based fatigue detection systems are too bulky or have limited accuracy due to prediction using single facial features or low-light conditions. Hence, the proposed method first enhances low-light images by improving the overall saturation and creating a uniform image using Gamma Correction. The enhanced images are then fed to a modified Multi-Task Cascaded Convolutional Neural Network for face detection and facial landmark extraction. Finally, the extracted eye state and mouth state features are fed to the LSTM network for fatigue classification. The output of this model decides whether the driver is fatigued or alert. The Mirror subset of the publicly available YawDD data set has been used for effective training and evaluation of the proposed model. The model achieved an exceptionally high F1 score of 0.98 and a Recall of 0.99 on the validation set.
据报道,疲劳驾驶是导致全球数百万人丧生的交通事故的主要原因。研究表明,大多数交通事故要么发生在夜间,要么发生在清晨,这时司机已经很疲劳,而且光线不足,无法注意到障碍物。一些自动疲劳检测系统使用生理信号,如脑电图、心电图和血压运动。但是,在大多数情况下,获取这些信号的侵入性使得它们不理想。最近开发的基于计算机视觉的疲劳检测系统过于笨重,或者由于使用单一面部特征或低光条件进行预测而具有有限的准确性。因此,提出的方法首先通过提高整体饱和度和使用伽玛校正创建均匀图像来增强低光图像。然后将增强后的图像馈送到改进的多任务级联卷积神经网络中进行人脸检测和面部地标提取。最后,将提取的眼态和口态特征输入LSTM网络进行疲劳分类。该模型的输出决定了驾驶员是疲劳还是警觉。公开可用的YawDD数据集的镜像子集已被用于对所提议的模型进行有效的训练和评估。该模型在验证集上获得了异常高的F1分数0.98和召回率0.99。
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引用次数: 0
Palm-sized Near-Infrared Spectroscopy and Machine Learning Analytics for the Detection of Endogenous Constituents and Drugs in Human Fingernails 手掌大小的近红外光谱和机器学习分析用于检测人类指甲中的内源性成分和药物
Pub Date : 2023-01-09 DOI: 10.1109/DeSE58274.2023.10100270
Megan Wilson, Dhiya Al-Jumeily Obe, Ismail Abbas, Iftikhar Khan, J. Birkett, Leung Tang, S. Assi
Near infrared (NIR) spectroscopy offers portable and rapid analysis of endogenous constituents and drugs within fingernails. Fingernails are a useful alternative biological matrix to blood and urine specimen as they provide the advantage of being non-invasive and require minimal sample size (1–3 mm). This work utilised NIR spectroscopy for the detection of (1) drugs in fingernails including benzocaine, calcium carbonate, cocaine hydrochloride (HCl), levamisole HCl, lidocaine HCl and procaine HCl; and (2) endogenous constituents such as carbohydrates, lipids, proteins and water. Fingernails were analysed initially ‘as received’ to identify the aforementioned endogenous constituents. Seven sets of fingernails were then spiked with one the identified drugs and measured over a six-week period. Spectra were exported into Matlab 2019a for spectral interpretation and machine learning analytics (MLAs). MLAs included correlation wavenumber space (CWS), principal component analysis (PCA) and Artificial Neural Networks Self-Organising Maps (SOM). The results showed that NIR spectra of spiked nails showed key characteristic features at specific wavelengths that corresponded to their spiked drug (1). When combined with CWS and PCA, NIR spectroscopy was able to differentiate between spiked and un-spiked nails and distinguish between the drugs that did not share similar chemical structures. CWS values (r values) and PCA loading scores highlighted spectra/spectral features that were significant. In addition, SOM showed further classes beyond PCA that corresponded to changes in physical properties of the fingernails. Thus, finding confirmed that NIR spectroscopy combined with MLAs possessed the ability to characterise fingernails based on their endogenous constituents and to detect the presence of drugs within fingernails.
近红外(NIR)光谱提供了便携式和快速分析指甲内的内源性成分和药物。指甲是血液和尿液标本的一种有用的替代生物基质,因为它们具有非侵入性和最小样本量(1-3毫米)的优点。本研究利用近红外光谱技术对指甲中苯佐卡因、碳酸钙、盐酸可卡因(HCl)、左旋咪唑HCl、利多卡因HCl和普鲁卡因HCl等药物进行了检测;(2)内源性成分,如碳水化合物、脂类、蛋白质和水。指甲最初进行了“接收”分析,以确定上述内源性成分。然后在七组指甲中加入一种确定的药物,并在六周内进行测量。将光谱导出到Matlab 2019a中,用于光谱解释和机器学习分析(mla)。MLAs包括相关波数空间(CWS)、主成分分析(PCA)和人工神经网络自组织映射(SOM)。结果表明,钉钉的近红外光谱在特定波长处显示出与所加药对应的关键特征(1)。结合CWS和PCA,近红外光谱可以区分钉钉和未钉钉,也可以区分化学结构不相似的药物。CWS值(r值)和PCA加载分数突出了显著的光谱/光谱特征。此外,SOM还显示了除PCA之外的其他类别,这些类别与指甲物理性质的变化相对应。因此,研究结果证实,近红外光谱与MLAs结合,能够根据指甲的内源性成分来表征指甲,并检测指甲内是否存在药物。
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引用次数: 0
BEsafe - Validating URLs and Domains with the aid of Indicator of Compromise BEsafe -使用妥协指示器验证url和域
Pub Date : 2023-01-09 DOI: 10.1109/DeSE58274.2023.10099965
Chang Deng Khai, Julia Juremi
The advancement of information technology has stimulated the conversion of physical interactions to online activities, especially during the Covid-19 pandemic. Thus, users' awareness and cyber hygiene need to be emphasized when they are involved in the cyber world. A browser extension named “BEsafe” is developed to validate the websites and promote a safe browsing environment. It prevents users from falling prey to network-based attacks and raises their security awareness. To ensure users' privacy, the permissions needed for BEsafe are listed on the permission tab. Moreover, BEsafe will not be working on Incognito mode by default to promise that the private mode leaves no tracks. However, the user can still enable the extension to be functioning on Incognito mode by navigating to the Extension Details and turning on the relevant toggle.
信息技术的进步促进了实体互动向在线活动的转变,特别是在2019冠状病毒病大流行期间。因此,当用户参与到网络世界中时,需要强调用户的意识和网络卫生。开发了一个名为“BEsafe”的浏览器扩展,以验证网站并促进安全的浏览环境。它可以防止用户成为基于网络的攻击的牺牲品,并提高他们的安全意识。为了确保用户的隐私,BEsafe所需的权限列在权限页签中。此外,BEsafe默认情况下不会在隐身模式下工作,以保证私有模式不会留下痕迹。但是,用户仍然可以通过导航到扩展详细信息并打开相关开关,使扩展在隐身模式下运行。
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引用次数: 0
COVID QA Network: A Specific Case of Biomedical Question Answering COVID问答网络:生物医学问答的具体案例
Pub Date : 2023-01-09 DOI: 10.1109/DeSE58274.2023.10099510
Amar Kumar, Rupal Bhargava, M. Jayabalan
COVID-19 crisis has led to an outburst of information that needs to be organized, validated, and made available to the seekers. Despite the rapid growth and success of BERT models in the last 3 years, COVID QA is a difficult task due to the lack of applicable datasets and a relevant language representation. Therefore, this study proposes a transformer-based Question Answering (QA) model for COVID-19 questions from the biomedical domain. Further, explored several datasets, and models required for question type prediction, no-answer prediction, and answer extraction and transfer learning strategies. It has been demonstrated that the exact match score can be significantly improved with limited amounts of training data from the biomedical domain. Finally, the findings of the study have been summarized as Factoid QA Finetuning Framework (FQFF), which can provide initial direction for domain-specific QA tasks with a limited amount of data.
COVID-19危机导致了大量信息的爆发,这些信息需要组织、验证并提供给寻求者。尽管BERT模型在过去3年中取得了快速增长和成功,但由于缺乏适用的数据集和相关的语言表示,COVID QA仍然是一项艰巨的任务。因此,本研究针对生物医学领域的COVID-19问题提出了基于转换器的问答(QA)模型。进一步,探讨了问题类型预测、无答案预测、答案提取和迁移学习策略所需的几个数据集和模型。已经证明,精确匹配分数可以显著提高与有限数量的训练数据从生物医学领域。最后,将研究结果总结为Factoid QA微调框架(FQFF),该框架可以在有限的数据量下为特定领域的QA任务提供初始方向。
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引用次数: 0
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2023 15th International Conference on Developments in eSystems Engineering (DeSE)
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