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Genetic Variability and Heritability of Morpho-Agronomic Traits, Oil Yield and Fatty Acid Components in Linseed (Linumusitatissimum L.) Germplasm in Ethiopia 埃塞俄比亚亚麻籽(Linumusitatissimum L.)种质的形态-农艺性状、产油量和脂肪酸组分的遗传变异性和遗传力
Pub Date : 2024-07-08 DOI: 10.11648/j.ijbse.20241202.11
Tadesse Ghiday, Wassu Mohamed, Y. Tsehaye, A. Wakjira, Chemeda Daba, Teasfaye Disasa
Comprehensive information on genetic variability and selection parameters is very crucial to design breeding strategies. However, very limited information is available in Ethiopian linseed germplasm. Therefore, the present study was conducted to estimate genetic variability, broad sense heritability and genetic advance; and determine selection for 19 quantitative traits using 126 genotypes (120 Ethiopian linseed accessions and six released varieties). The analysis of variance showed highly significant (P < 0.01) differences for all of the traits demonstrating the presence of high genetic diversity among the studied linseed genotypes. Higher differences between PCV and GCV estimates were observed for seed yield per plant and biological yield per plant, signifying the importance of environmental factors influence. High heritability coupled with high genetic advance was observed for seed yield per plant and biological yield per plant, indicating that this high heritability is due to additive gene effects and therefore, selection can be effective for the improvement of linseed for these traits. In addition, moderate heritability coupled with moderate genetic advance was recorded for oil yield per hectare, number of capsules, number of secondary branches, days to maturity, seed yield per hectare and plant height. These results indicated the existence of intermediate expression in these traits for both additive and dominance gene effect. In the present study, high heritability coupled with high GAM was observed for seed yield per plant and biological yield per plant, indicating greater contribution of additive gene action for the expression of these traits; and therefore, improvement can be achieved through selection in these traits.
有关遗传变异性和选择参数的综合信息对于设计育种策略至关重要。然而,有关埃塞俄比亚亚麻籽种质的信息非常有限。因此,本研究利用 126 个基因型(120 个埃塞俄比亚亚麻籽登录品种和 6 个已发布的品种)来估计遗传变异性、广义遗传率和遗传进展,并确定 19 个数量性状的选择。方差分析显示,所有性状的差异都非常显著(P < 0.01),表明所研究的亚麻籽基因型之间存在高度遗传多样性。每株种子产量和每株生物产量的 PCV 和 GCV 估计值差异较大,表明环境因素影响的重要性。在单株种子产量和单株生物产量方面,观察到了高遗传率和高遗传进展,这表明高遗传率是由加性基因效应造成的,因此选择可以有效地改善亚麻籽的这些性状。此外,每公顷产油量、蒴果数、二次分枝数、成熟天数、每公顷种子产量和株高的遗传率和遗传进展均为中等。这些结果表明,在这些性状中存在加性和显性基因效应的中间表达。在本研究中,观察到单株种子产量和单株生物产量的遗传率高且 GAM 高,这表明加性基因作用对这些性状的表达有更大的贡献;因此,可以通过选择来改善这些性状。
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引用次数: 0
Therapeutic Potential of Persea americana Stem Bark in Lipopolysaccharide (LPS) Induced Hepatic Inflammation and Oxidative Stress in Mice 秘鲁苦木树皮对脂多糖(LPS)诱导的小鼠肝脏炎症和氧化应激的治疗潜力
Pub Date : 2024-04-02 DOI: 10.11648/j.ijbse.20241201.11
Babatunde Oluwatoyin, A. Olasunkanmi, Ore Ayokanmi
This study investigated the potential of Persea americana stem bark for the treatment of inflammation and oxidation in mice. Oxidative stress occurs in the body when there is serious imbalance between the generation of free radicals and the antioxidant defense system, inflammation is a natural defense mechanism against pathogens and it is associated with many pathogenic diseases such as microbial and viral infections, exposure to allergens, radiation and toxic chemicals, autoimmune and chronic diseases, obesity, consumption of alcohol, tobacco use, and a high-calorie diet. Plants offer significant potentials for development of new anti-inflammatory therapies and treatment of diseases associated with inflammation and Oxidation. Stem bark of Persea ameriacna was extracted using EtOH/H2O (80:20 v/v), the extract obtained was subjected to maceration using 3 different solvents, hexane fraction (PAHF), Ethyl-acetate fraction (PAEF) and methanol fraction (PAMF). The methanol fraction came out with the highest yield and was used for the animal study, 30 male mice was divided into 3 different groups, LPS was introduced in one of the groups, PAMF was later administered to the same group, The experiment shows that the extract was able to demonstrate significant reduction in inflammation and also ameliorate oxidation in mice. In conclusion the methanolic fraction of Persea americana stem bark might contain beneficial phytochemicals that can be explored as potential anti-inflammatory and oxidative therapy.
本研究调查了美洲鲈鱼茎皮治疗小鼠炎症和氧化的潜力。当体内自由基的生成与抗氧化防御系统之间出现严重失衡时,就会产生氧化应激。炎症是抵御病原体的一种自然防御机制,它与许多致病因素有关,如微生物和病毒感染、接触过敏原、辐射和有毒化学物质、自身免疫性疾病和慢性疾病、肥胖、饮酒、吸烟和高热量饮食。植物为开发新的抗炎疗法和治疗与炎症和氧化有关的疾病提供了巨大的潜力。用乙醇/H2O(80:20 v/v)萃取 Persea ameriacna 的茎皮,得到的提取物用 3 种不同的溶剂浸泡,分别是正己烷馏分(PAHF)、乙酸乙酯馏分(PAEF)和甲醇馏分(PAMF)。30 只雄性小鼠被分成 3 个不同的组,其中一组引入 LPS,然后在同一组中施用 PAMF,实验结果表明,该提取物能够显著减轻炎症,并改善小鼠体内的氧化作用。总之,美洲鲈鱼茎皮的甲醇部分可能含有有益的植物化学物质,可作为潜在的抗炎和氧化疗法加以开发。
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引用次数: 0
The Developments and Advancements in Ferroptosis Research for the Treatment of Pancreatic Cancer: A Review 用于治疗胰腺癌的铁蛋白沉积研究的发展与进步:综述
Pub Date : 2023-12-06 DOI: 10.11648/j.ijbse.20231104.12
Jingchang Zhang, Yongfu Zhao
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引用次数: 0
Multiple Myeloma Mimicking Bone Metastasis: The Contribution of Biochemistry Laboratory to Differential Diagnosis

模仿骨转移的多发性骨髓瘤:生化实验室对鉴别诊断的贡献
Pub Date : 2023-10-28 DOI: 10.11648/j.ijbse.20231104.11
S. Harrar, Abderrahim Raissi, Ayoub Bouchehboun, Ibtissam Mhirig, S. Chellak, A. Boukhira
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引用次数: 0
Statistical Shape Model of the Calcaneus Bone for Comprehensive Assessment of Three-Dimensional Morphology 三维形态综合评价的跟骨统计形状模型
Pub Date : 2023-08-28 DOI: 10.11648/j.ijbse.20231102.12
Jie He, Zhexiao Guo, Yongjin Zhou, Xiuyun Su, Guoxian Pei
: Calcaneus is the most susceptible tarsal bone to fractures, presenting the most challenging treatment for associated tissue damage. Intra-articular calcaneal fractures present substantial challenges for patients and surgeons due to their association with both immediate and delayed complications. The purposes of this study were to establish a method for three dimensional morphological measurements of the normal calcaneus, we develop a statistical shape model (SSM) of the calcaneus that incorporates CT scans to enable a comprehensive assessment of its three-dimensional morphology. Though surface-based registration and point-wise correspondence analysis, the left and right calcaneus bones were compared with a variety of shape analysis. The compactness and parallel analysis test on the statistical shape model yielded 7 prominent shape modes of variations (MoVs)
跟骨是最容易骨折的跗骨,是治疗相关组织损伤最具挑战性的部位。跟骨关节内骨折由于其与即时和延迟并发症的关联,给患者和外科医生带来了巨大的挑战。本研究的目的是建立一种正常跟骨的三维形态测量方法,我们开发了一个统计形状模型(SSM)的跟骨,结合CT扫描,使其三维形态的全面评估。通过基于表面的配准和逐点对应分析,对左右跟骨进行各种形状分析比较。统计形状模型的紧密性和并行性分析检验得到了7种显著形状变化模态(MoVs)。
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引用次数: 0
Assessment of Nasal Mucosal Healing with Different Nasal Packing Techniques: A Study of 100 Patients 不同鼻填塞技术对100例患者鼻黏膜愈合的影响
Pub Date : 2023-08-28 DOI: 10.11648/j.ijbse.20231102.11
Kashiroygoud Biradar, S. Kumar
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引用次数: 0
Evaluation Value of Brainstem Auditory Evoked Potentials in Rehabilitation of Children with Developmental Coordination Disorders 脑干听觉诱发电位在发育性协调障碍儿童康复中的评价价值
Pub Date : 2023-04-15 DOI: 10.11648/j.ijbse.20231101.13
Yue Ling, Wang Jing, L. Xiaoli, Bai Bing
: Objective: To investigate the effects of brainstem auditory evoked potentials (BAEP) in treatment of developmental coordination disorder (DCD) in children. Methods: A total of 87 high-risk children who was examined by brainstem auditory evoked potentials (BAEP) in our hospital from August 2017 to December 2018 were enrolled in the study. According to Peabody motor development scale, these patients were divided into developmental coordination disorder (DCD) group (n=54) and non-developmental coordination disorder (non-DCD) group (n=33). After 3-month comprehensive rehabilitation treatment, the latency and changes of BAEP were observed and compared between the two groups. Results: As compared with brainstem auditory evoked potentials (BAEP) in non-developmental coordination disorder (non-DCD) group, the III, V and I ~ III wave latencies in developmental coordination disorder (DCD) group were significantly prolonged (P<0.05). After comprehensive rehabilitation treatment, the latency of each wave of BAEP in developmental coordination disorder (DCD) group was significantly shortened (P<0.01), as compared with that before treatment and that in non-developmental coordination disorder (non-DCD) group (P>0.05). Conclusion: Brainstem auditory evoked potentials (BAEP) can comprehensively, objectively and sensitively reflect the conduction function of central nervous system in children with developmental coordination disorder (DCD), which has important clinical application value in the evaluation of early rehabilitation effects.
目的:探讨脑干听觉诱发电位(BAEP)在儿童发育协调障碍(DCD)治疗中的作用。方法:选取2017年8月至2018年12月在我院接受脑干听觉诱发电位(BAEP)检查的高危儿童87例为研究对象。根据Peabody运动发育量表将患者分为发育性协调障碍(DCD)组(n=54)和非发育性协调障碍(non-DCD)组(n=33)。综合康复治疗3个月后,观察并比较两组患者BAEP潜伏期及变化情况。结果:与非发育性协调障碍(non-DCD)组脑干听觉诱发电位(BAEP)相比,发育性协调障碍(DCD)组III、V、I ~ III波潜伏期明显延长(P0.05)。结论:脑干听觉诱发电位(BAEP)能全面、客观、灵敏地反映发育协调障碍(DCD)患儿中枢神经系统的传导功能,在早期康复效果评价中具有重要的临床应用价值。
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引用次数: 0
Discuss the Risk of the Ventilator and Evaluate the Effect of Ozone Disinfection 探讨呼吸机的危害及臭氧消毒效果评价
Pub Date : 2023-02-04 DOI: 10.11648/j.ijbse.20231101.12
Xiaoping Huang, Dacheng Mai, Guanyuan Chen, Jianbo Zhu, Xuguang Xu
: Objective: To understand the possibility of nosocomial risk in the internal pipeline of the ventilator, and to discuss the necessity of disinfection of the internal pipeline by comparing the total number of colonies in the experimental sampling pipeline. Methods: It is innovatively proposed to put the ventilator in a cubic confined space
目的:通过对实验取样管道菌落总数的比较,了解呼吸机内部管道存在医院风险的可能性,探讨对内部管道进行消毒的必要性。方法:创新性地提出将呼吸机放置在一个立方密闭空间内
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引用次数: 0
Associations Between Inflammation Biomarkers and Serum Ferritin and Zinc Concentrations in Preschool Children in Nepal 尼泊尔学龄前儿童炎症生物标志物与血清铁蛋白和锌浓度之间的关系
Pub Date : 2023-01-09 DOI: 10.11648/j.ijbse.20231101.11
S. Rijal, Sher Singh Dahit, Dibya Laxmi Manandhar, Sanjeev Kumar Sahani, K. Agho
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引用次数: 0
Prevalence of Thrombocytopenia Among Pregnant Women in Tripoli Region /Libya 的黎波里地区/利比亚孕妇血小板减少症患病率
Pub Date : 2021-10-29 DOI: 10.11648/J.IJBSE.20210904.12
Sumaya Elgodwi, Mustafa Lawar, Abdussattar Saadallah
Thrombocytopenia is the definition of a condition in which the number of platelets is less than 150,000 / ml, and this deficiency may be the result of a lack of platelet production in the bone marrow or an increase in their breakdown in the connective tissue. This condition is common in pregnant women, with a global prevalence of about 7%. This study aims to find out the prevalence of this condition among pregnant women in the Tripoli area. A cross-sectional study design was used to assess the prevalence of thrombocytopenia among pregnant women who have visited the obstetrical ward department of obstetrics and gynecology in Al jalaa Hospital, Tripoli from January to April 2021. 1700 pregnant women have been included in the study during their follow-up in Al jalaa hospital of gynecology and obstetrics at the time of the study. 2 milliliters of venous blood were collected under aseptic conditions and transferred into (EDTA) tubes. The complete blood cell counts were determined using a Sysmex analyzer. Sony computer CORE i7 was used, bivariable statistical analysis was carried on using Microsoft office excel to evaluate the effect of an independent variable over the dependent variable. Results shows that 18% of pregnant women were thrombocytopenic; this thrombocytopenia was increased with age, upon the classification and severity of thrombocytopenia 78.5% were mild, and 21.5% were moderate thrombocytopenic with no sever cases. Conclusion: It can be concluded that thrombocytopenia disorders in pregnancy are very common in the Tripoli region, the prevalence of thrombocytopenia increased with the increase in the gestational age to reach the maximum at the third trimester of gestation.
血小板减少症是指血小板数量少于150,000 / ml的一种情况,这种缺乏可能是由于骨髓中血小板产生不足或结缔组织中血小板分解增加所致。这种情况在孕妇中很常见,全球患病率约为7%。这项研究的目的是找出的黎波里地区孕妇中这种情况的患病率。采用横断面研究设计评估2021年1月至4月在的黎波里Al jalaa医院妇产科产科病房就诊的孕妇中血小板减少症的患病率。研究期间,在Al jalaa妇产医院随访的1700名孕妇被纳入研究。无菌条件下采集静脉血2毫升,转入(EDTA)管。使用Sysmex分析仪测定全血细胞计数。采用Sony电脑CORE i7,采用Microsoft office excel进行双变量统计分析,评价自变量对因变量的影响。结果显示,18%的孕妇血小板减少;血小板减少随着年龄的增长而增加,根据血小板减少的分类和严重程度,78.5%为轻度,21.5%为中度血小板减少,无严重病例。结论:妊娠期血小板减少症疾病在的黎波里地区非常普遍,随着孕龄的增加,血小板减少症的患病率增加,在妊娠晚期达到最大值。
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引用次数: 2
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International Journal of Biomedical Science and Engineering
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