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BENEFICIAL EFFECTS OF AWAKE PRONE POSITIONING IN COVID-19 PATIENTS WITH MODERATE TO SEVERE HYPOXEMIC RESPIRATORY FAILURE 醒卧位对中重度低氧性呼吸衰竭COVID-19患者的有益作用
Pub Date : 2021-06-06 DOI: 10.54112/pjicm.v2021i1.4
M. Rana, R. Pervaiz, B. Arif, F. Tariq, S. Tabassum, M. Siddiqui, S. Raza, MM Hafeez
Introduction: Coronavirus disease (COVID-19) is a leading cause of acute hypoxemic respiratory failure which can progress to acute respiratory distress syndrome (ARDS). These patients are deeply sedated, paralyzed and ventilated and prone positioning is known to help in these cases. Prone positioning has been known to help in ARDS cases, but they are ventilated deeply sedated and paralyzed. The aim of the current study was to assess the safety and potential benefits of awake prone positioning in COVID-19 patients with moderate to severe hypoxemic respiratory failure. Methods: This is a retrospective cohort study, performed at Bahira International Hospital Lahore. Record of confirmed COVID-19 patients with hypoxic respiratory failure was reviewed thoroughly to collect data. The duration, timing, frequency, tolerability, beneficial effects and adverse events during prone positioning were recorded from the medical records before and after self-prone positioning. Results: The current analysis showed that prone positioning is supportive to maintain good saturation (92%) as compared to keeping patients in spine position (82%). Conclusion: It can be concluded from the current study that prone position is helpful to maintain normal oxygen saturation even on low oxygen supply, helping in quick recovery and preventing oxygen induced damage to the lungs.
简介:冠状病毒病(COVID-19)是急性低氧性呼吸衰竭的主要原因,可发展为急性呼吸窘迫综合征(ARDS)。这些患者被深度镇静,瘫痪和通气,俯卧位已知有助于在这些情况下。众所周知,俯卧位对ARDS患者有帮助,但他们是通气的,深度镇静和瘫痪。本研究的目的是评估醒卧位对中至重度低氧性呼吸衰竭的COVID-19患者的安全性和潜在益处。方法:这是一项回顾性队列研究,在拉合尔Bahira国际医院进行。对确诊的COVID-19伴低氧性呼吸衰竭患者的记录进行全面查阅,收集资料。从自卧位前后的病历记录中记录自卧位的持续时间、时间、次数、耐受性、有益效果和不良事件。结果:目前的分析显示,与保持脊柱位(82%)相比,俯卧位有助于保持良好的饱和度(92%)。结论:本研究提示俯卧位在低供氧条件下仍能维持正常血氧饱和度,有利于快速恢复,防止氧致肺损伤。
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引用次数: 1
MORTALITY AND COVID-19: A SNAPSHOT OF A TERTIARY CARE FACILITY IN PAKISTAN 死亡率和covid-19:巴基斯坦三级医疗机构概况
Pub Date : 2021-05-18 DOI: 10.54112/pjicm.v2021i1.3
M. Rana, A. Qayyum, M. Hashmi, M. Saif, M. Munir, R. Pervaiz, S. Iqbal, MM Hafeez
Background: Since SARS CoV-2 infection began in China and has evolved into a pandemic, mortality associated with this illness has been under discussion and hypercoagubility, severe acute respiratory syndrome and septicemia with multiple organ insufficiency have been cursed as potential causes of death in cases infected with the novel coronavirus. We did a retrospective analysis of cases admitted to our highly dependent and intensive care unit, and we tried to identify the leading cause of death in our cases. Methods: This is a single center retrospective study carried out at Bahria International Hospital Lahore over a 3-month period (May 10th to July 10th 2020) in which we analyzed the clinical and biochemical profiles of the COVID-19 patients who died during this period. Results: A total of 108 patients were admitted during this period out of which 11 patients died. 7 of them were men and 4 women. Majority of them had sudden cardiac arrest due to acute coronary syndrome followed by multiorgan dysfunction syndrome and acute respiratory distress syndrome. Conclusion: Acute coronary syndrome due to hypercoagubility was the leading cause of death in our patients.
背景:自SARS CoV-2感染在中国开始并演变为大流行以来,与该疾病相关的死亡率一直在讨论中,高凝血、严重急性呼吸综合征和多器官功能不全的败血症被认为是感染新型冠状病毒病例的潜在死亡原因。我们对高度依赖重症监护室收治的病例进行了回顾性分析,并试图确定病例中的主要死亡原因。方法:本研究是在拉合尔巴利亚国际医院进行的一项为期3个月(2020年5月10日至7月10日)的单中心回顾性研究,我们分析了在此期间死亡的COVID-19患者的临床和生化特征。结果:住院108例,死亡11例。其中7名男性,4名女性。以急性冠状动脉综合征为主,其次为多器官功能障碍综合征和急性呼吸窘迫综合征。结论:高凝血引起的急性冠状动脉综合征是本组患者死亡的主要原因。
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引用次数: 0
Innovation of Audio-Visual Triage system in Combating the Spread of COVID-19 Infection and its efficacy: A Novel Strategy 新型视听分诊系统在抗击新冠肺炎疫情传播中的创新及其效果
Pub Date : 2020-11-12 DOI: 10.1101/2020.11.06.20223040
M. M. Hafeez, Mohammad-Reza Azhar, Hafiz Rizwan Zafar Chudhary, M. A. Rana, Arif Malik
During the novel coronavirus pandemic, also known as SARS-CoV-2 or COVID-19 pandemic, frontline healthcare professionals suffered psychological as well as pathological trauma due to the lack of preparation to cope with this unforeseen situation. The protocols to prevent the spread of this disease proved to be less effective than anticipated. In these circumstances, improvement of the existing triage system was felt and an AUDIO-VISUAL TRIAGE (AVT) system was introduced to enhance confidence as well as increase the safety of frontline healthcare professionals. The current analysis was performed from March 21, 2020, to April 28, 2020, until the completion of sixty response forms, at Bahria Town International Hospital, Lahore. Thirty participants (Group A) deployed on visual triage and other thirty (Group B) on AVT for screening suspected cases of COVID-19 infection. Anxiety levels were measured by using the GAD-7 scoring system and the participants of both groups were periodically tested for COVID-19 infection by PCR. Independent t-test was used to evaluate the significance of different variables at a confidence level of 95%. The result of the current study revealed the effectiveness of AVT for the screening of COVID-19 patients. There was a statistically significant increase in anxiety levels and SARS-CoV-2 infection rate in group A as compared to group B. Almost all participants in group A wanted to shift their place of work or ready to quit the job if they were forced to perform their duties at the same visual triage. AVT system for COVID-19 screening is proved to be better than visual triage. It is not only a simple and effective way to prevent the spread of diseases but also boosted the confidence of frontline healthcare professionals to fight against coronavirus spread.
在新型冠状病毒大流行期间,也被称为SARS-CoV-2或COVID-19大流行,由于缺乏应对这种不可预见情况的准备,一线医护人员遭受了心理和病理创伤。预防这种疾病传播的方案证明不如预期的有效。在这种情况下,我们认为现有的分流系统有所改善,并引入了视听分流系统,以增强前线医护人员的信心和提高他们的安全。目前的分析是在2020年3月21日至2020年4月28日期间在拉合尔巴利亚镇国际医院进行的,直到填写完60份回应表为止。30名参与者(A组)采用目视分诊,30名参与者(B组)采用AVT筛查COVID-19感染疑似病例。使用GAD-7评分系统测量焦虑水平,并通过PCR定期检测两组参与者的COVID-19感染情况。采用独立t检验评价不同变量的显著性,置信水平为95%。目前的研究结果揭示了AVT筛查COVID-19患者的有效性。与b组相比,a组的焦虑水平和SARS-CoV-2感染率在统计学上显著增加。如果被迫在相同的视觉分类中履行职责,a组的几乎所有参与者都想转移工作地点或准备辞职。AVT系统对COVID-19筛查的效果优于目测分诊。这不仅是一种简单有效的预防疾病传播的方法,也增强了一线医护人员抗击新冠病毒传播的信心。
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引用次数: 3
CULTURING, IDENTIFICATION AND DRUG RESISTANCE OF MYCOBACTERIUM TUBERCULOSIS IN SPUTUM SPECIMEN 痰标本结核分枝杆菌的培养、鉴定及耐药性分析
Pub Date : 1900-01-01 DOI: 10.54112/pjicm.v2021i1.5
B. Amir, Y. Javed, S. Hanif, M. Tahir, M. Rana, MM Hafeez
The development of low-cost, fast, and reliable methods for detecting Mycobacterium tuberculosis (MTB) infection and drug susceptibility is critical for tuberculosis control. The new microscopic examination of liquid drug susceptibility assay (MODS) examines early MTB colonies in a liquid medium, which permits for more convenient diagnosis and testing of drug susceptibility. The sensitivity of MODS (91%) was superior as compared to the sensitivity of different culture methods (92%). The MGIT and MODS were used to monitor tuberculosis-positive sputum samples for isoniazid and rifampin susceptibility. Concordance between MODS and MGIT was found in 89 percent of cases. MODS are the fastest method used for diagnostic and susceptibility testing (median, 10.0 or 9 days). MODS is a fast, low-cost, responsive, and particular method for detecting and testing MTB susceptibility; it is specifically well-suited utilize in growing countries with high infection rates and a growing number of multidrug-resistant cases.
开发低成本、快速、可靠的检测结核分枝杆菌(MTB)感染和药物敏感性的方法对结核病控制至关重要。新型液体药敏试验显微检查(MODS)在液体培养基中检测早期结核分枝杆菌菌落,使诊断和药敏试验更加方便。MODS的敏感性(91%)优于其他培养方法的敏感性(92%)。采用MGIT和MODS监测结核阳性痰样异烟肼和利福平敏感性。在89%的病例中发现了MODS和MGIT之间的一致性。MODS是用于诊断和药敏试验的最快方法(中位数,10.0或9天)。MODS是一种快速、低成本、反应灵敏、独特的检测和检测MTB敏感性的方法;它特别适合在感染率高、耐多药病例日益增多的发展中国家使用。
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引用次数: 4
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Pakistan Journal of Intensive Care Medicine
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