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Alcohol-related deaths - a retrospective study from the region of northern Slovakia. 与酒精有关的死亡——斯洛伐克北部地区的一项回顾性研究
Q4 Medicine Pub Date : 2016-01-01
Ivana Komáreková

The study of cases with post mortem blood ethanol concentration of 2.00 g/kg and higher was performed at the Institute of Forensic Medicine in Martin, covering the region of North Slovakia. The aim of the study was to quantify the fatal consequences of acute ethanol administration reflecting in the annual mortality range, establish the causes of death, age and gender distribution of the deceased population, place and time parameters of deaths. The analyzed period was throughout the years 1993-2012.

在覆盖北斯洛伐克地区的马丁法医研究所,对死后血液乙醇浓度为2.00 g/kg及以上的病例进行了研究。本研究的目的是量化反映年死亡率范围的急性乙醇给药的致命后果,确定死亡原因、死亡人口的年龄和性别分布、死亡地点和时间参数。分析时段为1993-2012年。
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引用次数: 0
Right haemothorax related to the rupture of abdominal aortic aneurysm. 右胸血与腹主动脉瘤破裂有关。
Q4 Medicine Pub Date : 2016-01-01
Filiz Eren, Nursel Türkmen İnanır, Bülent Eren, Berna Senel, Recep Fedakar

Reported case was 63 years old forester died suddenly in the village. Autopsy examination revealed massive coagulated haemorrhage filling the right hemithorax, neither free fluid nor blood were observed in the abdominal cavity. Abdominal aortic aneurysm 20x15x15 cm in size was examined. We aimed to report the rare case of abdominal aortic aneurysm presented with transdiafragmatic rupture and bleeding in the right hemithorax.

报告病例为该村63岁护林员突然死亡。尸检显示右半胸大量凝固性出血,腹腔内未见游离液体和血液。检查尺寸为20x15x15cm的腹主动脉瘤。我们的目的是报告一例罕见的腹主动脉瘤表现为经膈破裂和出血的右半胸。
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引用次数: 0
[Intracardial fungal multiplication of order Mucor in an almost totally carbonised part of a male body found after ten days missing]. [在失踪十天后发现的一具几乎完全碳化的男性尸体中发现了毛霉菌目的心内真菌增殖]。
Q4 Medicine Pub Date : 2016-01-01
Silvia Farkašová Iannaccone, Jaroslav Klán, Laura W Lamps, Daniel Farkaš, Marián Švajdler Ml, Miroslav Szabo

Determination of time of death belongs to the most difficult and also the most important issues for the medical examiners, especially those who deal with violent death. Besides the most frequently evaluated postmortal changes it is sometimes possible to perform the evaluation on the basis of less frequently observed findings. One of such findings is for example the fungal multiplication on the body or in the very close vicinity. Knowledge of moulds as well as information about their speed of growth should contribute to confirmation or negation of some information gained during police investigation. In this case report authors describe the macroscopically visible fungal intracardiac multiplication in heart chambers and aorta in an almost totally carbonised body which was missing for only ten days. Based on the molecular examination it was detected that the body belonged to the 64-year-old man who was repeatedly hospitalised in psychiatry for depression with suicidal tendencies. The last hospitalisation was six weeks before death and there was no organic disability. The cause of fire was a naked flame. The cause of death was burn injury or asphyxia. The almost total carbonisation did not allow to perform toxicological investigation. By histological investigation we found the presence of wide long non-septate moulds growing in the heart muscle, which belonged to the order Mucor. Since there was no obvious inflammatory response, we suppose their growth started on the congealed blood after death.

确定死亡时间是法医,特别是处理暴力死亡案件的法医最困难也是最重要的问题。除了最常评估的死后变化之外,有时也可以根据不太常观察到的发现进行评估。其中一个发现是真菌在身体上或非常接近的地方繁殖。对霉菌的了解以及有关其生长速度的信息应该有助于证实或否定警方在调查过程中获得的一些信息。在这个病例中,报告作者描述了一个几乎完全碳化的身体,在心脏腔室和主动脉中宏观可见的真菌增殖,这只消失了十天。根据分子检查,发现尸体属于一名64岁的男子,他因抑郁症和自杀倾向而多次住院治疗。最后一次住院是在死亡前六周,没有器质性残疾。起火的原因是明火。死因是烧伤或窒息。几乎完全碳化,不允许进行毒理学研究。通过组织学检查,我们发现在心肌中生长着宽而长而不分隔的霉菌,属于毛霉目。由于没有明显的炎症反应,我们推测它们是在人死后凝固的血液中开始生长的。
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引用次数: 0
[Fatal head injury caused by a crossbow arrow with unusually preserved posttraumatic volitional activity - case report]. [由具有异常保存的创伤后意志活动的弩箭造成的致命头部损伤-病例报告]。
Q4 Medicine Pub Date : 2016-01-01
Hynek Řehulka, Eva Čechová, Jitka Mottlová, Martin Valenta, Zdeněk Mareška

The authors deal with a case of suicidal attempt resulting in a fatal head injury. A young man shot himself with a serially produced mechanical sports crossbow. The young man with a critical intracranial injury, a penetration, was nevertheless capable of basic locomotive activity, as well as of coherent communication with another people present at the scene. The critically injured patient was transported from the scene directly to medical centre where he subsequently underwent a neurologic surgery. On the eight day after the incident he died in the hospital as a result of sustained wounds. During the autopsy, a penetrating arrow-shot wound head injury was certified, occurring in the right and left temple area. Signs of a complex decompressive craniectomy were established too. The shooting channel was generally horizontally oriented, extending from the right to the left side, from behind in a 10 up to 15 degrees angle to the frontal plane, penetrating the brain from the right temple lobe and the frontal lobe, thereby pervading also frontal horns of lateral ventricles, and from the left afflicting the frontal lobe on the left side of the brain. In the course of the shooting channel, brain contusion occurred, accompanied by intraventricular haemorrhage. In addition, a heavy cerebral oedema, multiple secondary malacias, Durett haemorrhages and extensive thrombosis of cerebral sinuses were stated. In the course of police investigation, based mainly on the information given by the wounded man right after he had been found at the scene, it was revealed that another person might have been involved. The forensic autopsy, the investigation of the Police and the subsequent criminalist-ballistics expert investigation, supported by a series of experimental substitutive target shots, didnt, however, decidedly prove that any other culprit had been involved.

作者处理了一个自杀企图导致致命头部损伤的案例。一名年轻人用一种系列生产的机械运动弩开枪自杀。这个年轻人颅内伤得很严重,被刺伤了,但他还能进行基本的运动,还能与在场的人进行连贯的交流。重伤患者被直接从现场送往医疗中心,随后接受了神经外科手术。事件发生后的第8天,他因伤势过重在医院死亡。在尸检过程中,一处穿透性的箭伤被证实是头部受伤,发生在左右太阳穴区域。复杂的减压颅骨切除术的迹象也被确立。射击通道一般呈水平方向,从右侧延伸至左侧,从后方与额平面呈10至15度角,从右侧太阳叶和额叶穿透大脑,从而也渗透到侧脑室的额角,并从左侧折磨左侧大脑的额叶。在拍摄过程中,出现脑挫伤,并伴有脑室内出血。此外,严重的脑水肿,多发性继发性疟疾,Durett出血和广泛的脑窦血栓形成。警方在调查过程中,主要根据受伤男子在现场被发现后提供的信息,发现可能有另一个人参与其中。然而,法医解剖、警方的调查以及随后的犯罪学家和弹道学专家的调查,以及一系列实验性的替代靶射击,都没有确凿地证明有其他罪犯参与其中。
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引用次数: 0
[Evolution of historical and social attitudes toward suicide]. [历史和社会对自杀态度的演变]。
Q4 Medicine Pub Date : 2016-01-01
Jozef Krajčovič

In the article there is the repeatedly submitted experience detailing how death is a fundamental element of our lives, including by ones own hand - suicide, cases of which forensic pathologists are confronted with every day. The subject of suicide has been treated by the public as taboo, while in reality we are confronted by it every day, particularly in forensic medicine, where we are not only obliged, but also find it our duty to inquire as to the reasons, motivation and other factors that have led someone to take their own life voluntarily. The author was required to investigate the sociogenesis and psychogenesis of suicidal acts, the influence of successive social and cultural changes within society on suicides focusing on the psychiatric-biological, as well as the wider socio-cultural and philosophical connections. All major religions were and continue to be strongly against the act of suicide, which affects any who attempt suicide, but also their relatives. This state of affairs continued to develop until Durkheim, who initially established scientific research of suicides, primarily from a psychologicalsocial viewpoint. Suicide has been the final act of many world-renowned, as well as national, personalities, such as writers, artists, musicians and actors.

在文章中有反复提交的经验,详细说明了死亡是我们生活的基本要素,包括自杀,法医病理学家每天都要面对的案例。自杀的话题一直被公众视为禁忌,而在现实中,我们每天都要面对它,尤其是在法医领域,我们不仅有义务,而且有责任去调查导致某人自愿结束自己生命的原因、动机和其他因素。作者被要求调查自杀行为的社会发生和心理发生,社会中连续的社会和文化变化对自杀的影响,重点是精神生物学,以及更广泛的社会文化和哲学联系。所有主要宗教过去和现在都强烈反对自杀行为,这不仅影响到任何企图自杀的人,也影响到他们的亲属。这种状况一直持续发展到迪尔凯姆,他最初建立了自杀的科学研究,主要是从心理社会的角度出发。自杀是许多世界知名人士乃至全国知名人士的最后行为,比如作家、艺术家、音乐家和演员。
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引用次数: 0
Death due to coronary artery anomaly with coexistence of Chiari network. 冠状动脉异常死亡伴Chiari神经网络共存。
Q4 Medicine Pub Date : 2015-01-01
Nursel İnanir Türkmen, Büllent Eren, Murat Serdar Gürses, Okan Akan, Filiz Eren, Fabian Kanz

Coronary artery anomalies rarely detected in autopsy series and angiograms can be a component of complex malformations, besides, can be also associated with sudden cardiac death. Presented case was 22-year-old male, who had suddenly fainted during a football match played on artificial turf, he was transferred into the hospital, however had died during intensive care therapy. He had been evaluated by local prosecutor, and sent to our center for autopsy. At autopsy, internal macroscopic examination revealed absence of the right coronary artery. A total of two coronary artery ostia were observed. One of them originated from the left aortic sinus, and the other one stemmed from 8 mm above the sinotubular line. Besides, Chiari network formation was seen in the right atrium. This case with coronary artery anomaly associated with formation of Chiari network was discussed from the perspective of forensic medicine in the light of the literature information.

冠状动脉异常在尸检系列和血管造影中很少发现,可能是复杂畸形的组成部分,也可能与心源性猝死有关。该病例为22岁男性,他在一场人造草皮足球比赛中突然晕倒,他被转移到医院,但在重症监护治疗期间死亡。当地检察官对他进行了评估,并将他送到我们中心进行尸检。尸检时,内部宏观检查显示右冠状动脉缺失。共观察到2个冠状动脉开口。其中一处起源于左主动脉窦,另一处起源于窦管线上方8mm处。此外,右心房可见Chiari网络形成。本文结合文献资料,从法医学角度对冠状动脉异常伴Chiari网络形成的病例进行探讨。
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引用次数: 0
[Two sudden deaths of children with mesenterium commune -- a case report]. [2例肠系膜公社儿童猝死病例报告]。
Q4 Medicine Pub Date : 2015-01-01
Kateřina Grusová, Milan Votava, Martin Zeman

Congenital anomalies of the digestive system represent a complicated topic concerning many medical specializations. The goal of this article is to describe two cases of children with mesenterium commune. First was an infant (5.5 months old female) who died shortly after being admitted to hospital with acute bronchitis, vomiting and diarrhoea. The autopsy revealed the cause of death--volvulus of the entire small intestine and the first portion of the large intestine with haemorrhagic infarsation of the intestinal wall in an infant with congenital anomaly of intestinal fixation--mesenterium commune. Second case was a 2.5 years old female after two heart surgeries, with pulmonary hypertension, who died suddenly at home. The cause of death was volvulus of a portion of the small intestine with haemorrhagic infarsation of the intestinal wall and also mesenterium commune. Congenital malpositions of the intestine originate due to malrotation and malfixation of the intestine during prenatal and early postnatal period. This wide range of the individuals developmental disorders always result in a condition where the topographical findings in the abdominal cavity are not as commonly found. Abnormally positioned intestines cannot develop a normal mesentery and are prone to volvulus, which represents the most serious complication with acute abdominal symptoms and when diagnosed late, it can lead to sudden death. Whilst performing autopsies such cases are rarely seen. However in forensic medicine and also in clinical practice it is important to consider intestinal malposition as a cause of acute abdomen.

消化系统的先天性异常代表了一个涉及许多医学专业的复杂话题。本文的目的是描述两例儿童肠系膜公社。首先是一名婴儿(5.5个月大的女婴),因急性支气管炎、呕吐和腹泻入院后不久死亡。尸检揭示了死亡原因——整个小肠和大肠的第一部分扭转并肠壁出血性梗死——先天性肠固定异常婴儿——肠系膜阻塞。第二例为2次心脏手术后的2.5岁女性,肺动脉高压,在家中猝死。死亡原因是部分小肠扭转,肠壁和肠系膜发生出血性梗死。先天性肠畸形是由于肠道在产前和产后早期的旋转和固定不良而引起的。这种范围广泛的个体发育障碍总是导致一种情况,即在腹腔的地形发现并不常见。位置异常的肠道不能形成正常的肠系膜,容易发生肠扭转,这是急性腹部症状最严重的并发症,如果诊断晚,可导致猝死。在进行尸检时,这种情况很少见到。然而,在法医学和临床实践中,考虑肠道错位是引起急腹症的重要原因。
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引用次数: 0
A fatal case of poisoning with ethanol and psychotropic drugs with putrefactive changes. 酒精及精神药物中毒致溃烂性改变1例。
Q4 Medicine Pub Date : 2015-01-01
Hiroshi Kinoshita, Naoko Tanaka, Mostofa Jamal, Mitsuru Kumihashi, Ayaka Takakura, T Tobiume, Kunihito Tsutsui, Kiyoshi Ameno

We present a fatal case involving poisoning with paroxetine, flunitrazepam, and ethanol, with putrefactive changes. Quantitative toxicological analysis showed that the concentrations of paroxetine and 7-aminoflunitrazepam, a metabolite of flunitrazepam, in the femoral blood were 0.28 µg/ml and 0.17 µg/ml, respectively. We also detected an ethanol level of 2.90 mg/ml and an n-propanol level of 0.10 mg/ml. We concluded that the cause of death was due to the interaction of paroxetine, flunitrazepam, and ethanol. The effects of putrefactive changes should be considered during forensic toxicological evaluation.

我们提出一个致命的案例,涉及帕罗西汀,氟硝西泮和乙醇中毒,与腐烂的变化。定量毒理学分析显示,股骨血液中帕罗西汀和氟硝西泮代谢物7-氨基氟硝西泮的浓度分别为0.28µg/ml和0.17µg/ml。我们还检测到乙醇含量为2.90 mg/ml,正丙醇含量为0.10 mg/ml。我们的结论是,死亡的原因是由于帕罗西汀,氟硝西泮和乙醇的相互作用。在法医毒理学评估中应考虑到腐烂变化的影响。
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引用次数: 0
[Confrontation of knowledge on alcohol concentration in blood and in exhaled air]. [血液和呼出空气中酒精浓度知识的对抗]。
Q4 Medicine Pub Date : 2015-01-01
Miroslav Bauer, Jiřina Bauerová, Ján Šikuta, Jozef Šidlo

The authors of the paper give a brief historical overview of the development of experimental alcohology in the former Czechoslovakia. Enhanced attention is paid to tests of work quality control of toxicological laboratories. Information on results of control tests of blood samples using the method of gas chromatography in Slovakia and within a world-wide study "Eurotox 1990" is presented. There are pointed out the pitfalls related to objective evaluation of the analysis results interpreting alcohol concentration in biological materials and the associated need to eliminate a negative influence of the human factor. The authors recommend performing analyses of alcohol in biological materials only at accredited workplaces and in the case of samples storage to secure a mandatory inhibition of phosphorylation process. There are analysed the reasons of numerical differences of analyses while taking evidence of alcohol in blood and in exhaled air. The authors confirm analysis accuracy using the method of gas chromatography along with breath analysers of exhaled air. They highlight the need for making the analysis results more objective also through confrontation with the results of clinical examination and with examined circumstances. The authors suggest a method of elimination of the human factor, the most frequently responsible for inaccuracy, to a tolerable level (safety factor) and the need of sample analysis by two methods independent of each other or the need of analysis of two biological materials.

本文的作者简要介绍了前捷克斯洛伐克实验酒精学发展的历史概况。加强对毒理学实验室工作质量控制检测的重视。报告介绍了在斯洛伐克使用气相色谱法对血液样本进行对照试验的结果以及在一项世界范围的研究"Eurotox 1990"中进行对照试验的结果。指出了客观评价解释生物材料中酒精浓度的分析结果以及消除人为因素负面影响的相关需要存在的缺陷。作者建议仅在认可的工作场所和样品存储的情况下对生物材料中的酒精进行分析,以确保对磷酸化过程的强制性抑制。分析了血液中酒精含量和呼出空气中酒精含量测定结果差异较大的原因。采用气相色谱法和呼气分析仪对呼出空气进行分析,验证了分析的准确性。他们强调需要通过与临床检查结果和检查情况的对照,使分析结果更加客观。作者建议一种方法,消除人为因素,最经常负责不准确,到一个可容忍的水平(安全系数)和需要两种方法的样品分析相互独立或需要分析两种生物材料。
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引用次数: 0
Truncus arteriosus communis with survival to the age of 46 years: case report. 动脉丛干存活至46岁1例。
Q4 Medicine Pub Date : 2015-01-01
Alžbeta Ginelliová, Daniel Farkaš, Silvia Farkašová Iannaccone

Truncus arteriosus communis is an uncommon congenital cardiovascular malformation characterized by a single arterial trunk that arises from the base of the heart and gives rise to the coronary, pulmonary and systemic arteries. The prognosis in truncus arteriosus is very poor without surgical correction. The median age at death without surgery ranges from 2 weeks to 3 months, with 85 % mortality by age 1 year. The authors report the autopsy findings of a 46 year old man with truncus arteriosus communis without surgical intervention who died at the hospital shortly after admission.

社区动脉干是一种罕见的先天性心血管畸形,其特征是单一的动脉干,起源于心脏底部,并产生冠状动脉,肺动脉和全身动脉。如果不进行手术矫正,动脉干的预后很差。无手术死亡的中位年龄为2周到3个月,1岁死亡率为85%。作者报告了一名未经手术治疗的46岁男性共动脉干患者的尸检结果,该患者在入院后不久死亡。
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引用次数: 0
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Soudni Lekarstvi
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