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Current perspectives on sustainable technologies for effective valorization of industrial meat waste: Opening the door to a greener future. 对工业肉类废弃物有效增值的可持续技术的当前观点:打开通往更绿色未来的大门。
Q1 Agricultural and Biological Sciences Pub Date : 2025-01-01 Epub Date: 2025-05-09 DOI: 10.1016/bs.afnr.2025.04.006
Burcu Ozturk-Kerimoglu, Muge Urgu-Ozturk, Onur Ozdikicierler, Monika Modzelewska-Kapituła, Katarzyna Tkacz

Food waste poses a significant threat by disrupting the global economy and negatively affecting the environment by contributing to higher emissions, water wastage, land degradation, and loss of biodiversity. Worldwide, a significant amount of food waste is generated throughout the entire process chain, from raw material to final product, with a substantial portion originating from the meat industry. Recently, the notable rise in meat production has inevitably resulted in a higher volume of waste generation. Meat-derived residues should be effectively utilized due to their diversity, organic content, and contribution to increasing the carbon footprint. Meat waste can be transformed into numerous high-value alternative products for further utilization in various industrial sectors. The application of green technologies has become a critical approach in recent years to ensure sustainable production by converting such waste into valuable components. As a part of this approach, various technologies, such as enzymatic hydrolysis, ultrasound-assisted extraction, supercritical fluid extraction, instant catapult steam explosion, and ohmic heating come to the forefront. In the current chapter, the potential applications of green technologies in converting by-products and co-products obtained during meat processing into value-added products are compiled and analyzed from the perspective of sustainability.

食物浪费扰乱了全球经济,对环境造成了负面影响,导致排放增加、水资源浪费、土地退化和生物多样性丧失,对环境构成了重大威胁。在世界范围内,从原材料到最终产品的整个过程链中产生了大量的食物浪费,其中很大一部分来自肉类行业。最近,肉类生产的显著增加不可避免地导致了更多的废物产生。肉类残留物由于其多样性、有机含量和增加碳足迹的贡献,应该得到有效利用。肉类废物可以转化为许多高价值的替代产品,供各种工业部门进一步利用。近年来,应用绿色技术已成为确保可持续生产的关键方法,将此类废物转化为有价值的部件。作为这一方法的一部分,各种技术,如酶水解、超声波辅助提取、超临界流体提取、即时弹射蒸汽爆炸和欧姆加热等都走在了前列。在本章中,从可持续性的角度对绿色技术在肉类加工过程中获得的副产品和副产品转化为增值产品方面的潜在应用进行了整理和分析。
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引用次数: 0
Phage biocontrol: Enhancing food safety through effective pathogen reduction. 噬菌体生物防治:通过有效减少病原体来提高食品安全。
Q1 Agricultural and Biological Sciences Pub Date : 2025-01-01 Epub Date: 2025-05-03 DOI: 10.1016/bs.afnr.2025.04.008
Silvina Alicia Pujato, Mariángeles Briggiler-Marcó, Diego Javier Mercanti

Bacteriophages (phages) are viruses that specifically target bacteria, offering a promising biocontrol strategy for food safety. Their high specificity enables precise pathogen elimination without disturbing beneficial microbiota. Historically overshadowed by antibiotics, phage biocontrol is now regaining interest due to the rise of multidrug-resistant bacteria and increasing food safety concerns. Phages effectively reduce foodborne pathogens such as Escherichia coli O157:H7, Salmonella enterica, and Listeria monocytogenes in fresh produce, meat, and dairy products. Phage-based interventions can be applied pre- and post-harvest, acting as direct antimicrobial agents or as enhancers of existing preservation methods. Furthermore, phages offer advantages in combating biofilms, a major concern in food processing facilities. Despite their potential, challenges such as bacterial resistance, regulatory constraints, and large-scale production hurdles remain. This chapter discusses the evolution of phage biocontrol, its applications in food safety, and the challenges that must be addressed for its widespread adoption. Phages represent an innovative, eco-friendly alternative to conventional antimicrobials, aligning with the global demand for safer and more sustainable food production practices.

噬菌体是一种专门针对细菌的病毒,为食品安全提供了一种有前途的生物防治策略。它们的高特异性能够在不干扰有益微生物群的情况下精确消除病原体。由于耐多药细菌的增加和日益增加的食品安全问题,噬菌体生物防治在历史上被抗生素所掩盖,现在正重新引起人们的兴趣。噬菌体有效地减少了新鲜农产品、肉类和乳制品中的食源性病原体,如大肠杆菌O157:H7、肠炎沙门氏菌和单核细胞增生李斯特菌。基于噬菌体的干预措施可以在收获前和收获后应用,作为直接抗菌剂或作为现有保存方法的增强剂。此外,噬菌体在对抗生物膜方面具有优势,生物膜是食品加工设施的主要关注点。尽管具有潜力,但诸如细菌耐药性、监管限制和大规模生产障碍等挑战仍然存在。本章讨论了噬菌体生物防治的发展,其在食品安全中的应用,以及广泛采用噬菌体必须解决的挑战。噬菌体是传统抗菌剂的一种创新的、环保的替代品,符合全球对更安全和更可持续的粮食生产做法的需求。
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引用次数: 0
Preface. 前言。
Q1 Agricultural and Biological Sciences Pub Date : 2025-01-01 DOI: 10.1016/S1043-4526(25)00013-0
Prof Dr Anderson S Sant'Ana
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引用次数: 0
Predictive microbiology through the last century. From paper to Excel and towards AI. 预测微生物学贯穿了上个世纪。从纸到Excel再到人工智能。
Q1 Agricultural and Biological Sciences Pub Date : 2025-01-01 Epub Date: 2024-10-22 DOI: 10.1016/bs.afnr.2024.09.012
Alberto Garre, Pablo Fernández, Eduard Grau-Noguer, Silvia Guillén, Samuel Portaña, Arícia Possas, Montserrat Vila

This chapter provides a historical perspective on predictive microbiology: from its inception till its current state, and including potential future developments. A look back to its origins in the 1920s underlies that scientists at the time had great ideas that could not be developed due to the lack of proper technologies. Indeed, predictive microbiology advancements mostly halted till the 1980s, when computing machines became broadly available, evidencing how these technologies were an enabler of predictive microbiology. Nowadays, predictive microbiology is a mature scientific field. There is a general consensus on experimental and computational methodologies, with software tools implementing these principles in a user-friendly manner. As a result, predictive microbiology is currently a useful tool for researchers, food industries and food safety legislators. On the other hand, this methodology has some important limitations that would be hard to solve without a reconsideration of some of its basic principles. In this sense, Artificial Intelligence and Data Science present great promise to advance predictive microbiology even further. Nevertheless, this would require the development of a novel conceptual framework that accommodates these novel technologies into predictive microbiology.

本章提供了预测微生物学的历史观点:从它的开始到现在的状态,包括潜在的未来发展。回顾它在20世纪20年代的起源,可以看出当时的科学家有很多伟大的想法,但由于缺乏适当的技术而无法实现。事实上,预测微生物学的进展一直停滞到20世纪80年代,当时计算机变得广泛可用,证明了这些技术如何成为预测微生物学的推动者。预测微生物学是一个成熟的科学领域。在实验和计算方法上有一个普遍的共识,用软件工具以用户友好的方式实现这些原则。因此,预测微生物学目前是研究人员、食品工业和食品安全立法者的有用工具。另一方面,这种方法有一些重要的限制,如果不重新考虑它的一些基本原则,就很难解决这些限制。从这个意义上说,人工智能和数据科学为进一步推进预测微生物学提供了巨大的希望。然而,这需要开发一种新的概念框架,将这些新技术纳入预测微生物学。
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引用次数: 0
Food fermentations: NIR spectroscopy as a tool for process analytical technology. 食品发酵:近红外光谱作为过程分析技术的工具。
Q1 Agricultural and Biological Sciences Pub Date : 2025-01-01 Epub Date: 2025-07-28 DOI: 10.1016/bs.afnr.2025.06.002
Cristina Alamprese, Silvia Grassi

Fermentation is a cornerstone of the food system, offering several benefits in nutrition, food safety, sustainability, and sensory quality. Historically rooted in food preservation and cultural practices, fermentation has evolved into a dynamic biotechnological tool, spanning diverse applications from dairy, meat, vegetable, and plant-based foods to by-product valorization. The process leverages microbial metabolisms (primarily lactic acid bacteria, yeasts, and molds) to enhance shelf life and sensory properties, improve digestibility, and generate bioactive compounds. Advances in precision fermentation and strain engineering have further extended fermentation potential to address emerging food challenges. Traditional fermentation monitoring relies on manual, off-line techniques that lack real-time responsiveness. The integration of advanced sensor technologies, artificial intelligence (AI), and process analytical technology (PAT) enables real-time, non-invasive process control. Among these tools, near-infrared (NIR) spectroscopy stands out due to its speed, low cost, minimal sample preparation, and compatibility with multivariate data analysis. NIR spectroscopy, combined with machine learning models, has demonstrated robust performance in predicting fermentation parameters across multiple food matrices, including alcoholic beverages, dairy, plant and meat fermented products, bread, kombucha, and vinegar. However, challenges such as spectral complexity, calibration transferability, and model interpretability persist. Future perspectives emphasize the convergence of NIR spectroscopy with digital twins, hybrid modeling, and explainable AI, enabling self-optimizing, adaptive fermentation systems. Emerging NIR devices offer portability and scalability, democratizing access to smart fermentation control for both industrial and artisanal producers. This paradigm shift lays the groundwork for intelligent, sustainable, and precision-driven food fermentation.

发酵是食品系统的基石,在营养、食品安全、可持续性和感官质量方面提供了几个好处。历史上起源于食品保存和文化实践,发酵已发展成为一种动态的生物技术工具,从乳制品、肉类、蔬菜和植物性食品到副产品增值,应用范围广泛。该工艺利用微生物代谢(主要是乳酸菌、酵母和霉菌)来延长保质期和感官特性,提高消化率,并产生生物活性化合物。精密发酵和菌种工程的进步进一步扩展了发酵的潜力,以解决新出现的食品挑战。传统的发酵监测依赖于缺乏实时响应能力的人工离线技术。先进的传感器技术、人工智能(AI)和过程分析技术(PAT)的集成实现了实时、非侵入性的过程控制。在这些工具中,近红外(NIR)光谱因其速度快、成本低、样品制备最少以及与多变量数据分析的兼容性而脱颖而出。近红外光谱与机器学习模型相结合,在预测多种食品基质的发酵参数方面表现出了强大的性能,包括酒精饮料、乳制品、植物和肉类发酵产品、面包、康普茶和醋。然而,诸如光谱复杂性、校准可转移性和模式可解释性等挑战仍然存在。未来的观点强调近红外光谱与数字双胞胎、混合建模和可解释的人工智能的融合,使自优化、自适应发酵系统成为可能。新兴的近红外设备提供便携性和可扩展性,使工业和手工生产者的智能发酵控制民主化。这种模式的转变为智能、可持续和精确驱动的食品发酵奠定了基础。
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引用次数: 0
Advances in microbial C-reactive peptides as pro-sensors for antibiotic release and membrane driving potentials. 微生物c反应肽作为抗生素释放和膜驱动电位前传感器的研究进展。
Q1 Agricultural and Biological Sciences Pub Date : 2025-01-01 Epub Date: 2025-07-04 DOI: 10.1016/bs.afnr.2025.04.012
Sami Saadi, Nor Elhouda Nacer, Halima Boughellout, Férial Aziza Benyahia, Adoui Faiza, Farooq Anwar, Abdul Azis Ariffin, Abdelghani Boudjellal, Hasanah Mohd Ghazali, Nazamid Saari, Abdulkarim Sabo Mohammed

The involvement of C-reactive proteins in triggering antibiotic release is important in figuring out the underlaying mechanisms of cellular biomarkers involving the immune reaction and inflammation. Thus, the existence of microbial C-reactive proteins or peptides are getting logical acceptance due to the presence of some homologue peptides into microbes capable in triggering same inflammatory response levels like to that happening into mammalian cells. The objective of this chapter is to study in depth the mechanization of microbial C-reactive proteins/peptides for allowing the release of de novo antibiotics capable in competing the penicillin mechanism of action. Therefore, series of plasmo-dynamic markers are beared in mind and studied including the role of anti-inflammatory peptides, peptide transporters, opioid peptides, cell penetrating peptides and other static membrane markers including Toll-like receptor, and G-protein coupled receptors. These cellular biomarkers are studied in light of their mechanizations toward the release of commonly known classes of antibiotics including antiviral, antifungal, and antimicrobial ones. The chapter is also covering the availability of antibiotics in foods, microbes, biological matrices and in animal cells and tissues as well as the methods of detection and quantification of antibiotics and also the commonly methods used in mitigating those antibiotics when they are present in excessive doses in food materials. In this regard, some engineered models have been developed in order to remove residual traces of antibiotics as mode for food safety purposes. The domain applications of antibiotics as putative cores and therapies used for preventing the burden diseases like Covid-19 pandemia and other complicated transient diseases are also covered. The chapter is shedding light on the mechanization of peptides like antibiotics, microbial resistance against antibiotics, mechanism of antibiotic sensing, peptides-antibiotic interaction, and antibiotic resistance, by projecting lights on some developed biosensors used in detecting these type of substances.

c反应蛋白在触发抗生素释放中的作用对于弄清涉及免疫反应和炎症的细胞生物标志物的潜在机制非常重要。因此,微生物c反应蛋白或多肽的存在得到了合理的接受,因为一些同源多肽存在于微生物中,能够引发与哺乳动物细胞相同的炎症反应水平。本章的目的是深入研究微生物c反应蛋白/肽的机械化,以允许释放能够竞争青霉素作用机制的新抗生素。因此,我们关注并研究了一系列血浆动态标志物,包括抗炎肽、肽转运体、阿片肽、细胞穿透肽和其他静态膜标志物,包括toll样受体、g蛋白偶联受体的作用。这些细胞生物标志物是根据它们的机制来研究的,这些机制有助于释放众所周知的抗生素,包括抗病毒、抗真菌和抗微生物抗生素。本章还涵盖了食品、微生物、生物基质以及动物细胞和组织中抗生素的可用性,以及抗生素的检测和定量方法,以及在食品材料中过量使用抗生素时用于减轻这些抗生素的常用方法。在这方面,已经开发了一些工程模型,以去除残留的抗生素痕迹,作为食品安全的模型。还涵盖了抗生素作为假定核心的领域应用和用于预防负担性疾病(如Covid-19大流行和其他复杂的一过性疾病)的治疗方法。本章通过展示一些用于检测这些类型物质的先进生物传感器,揭示了肽类抗生素的机械化,微生物对抗生素的耐药性,抗生素感知机制,肽类抗生素相互作用和抗生素耐药性。
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引用次数: 0
Yeast extract as a more sustainable food ingredient: Insights into flavor and bioactivity. 酵母提取物作为一种更可持续的食品成分:对风味和生物活性的见解。
Q1 Agricultural and Biological Sciences Pub Date : 2025-01-01 Epub Date: 2024-10-18 DOI: 10.1016/bs.afnr.2024.09.002
Yu Fu

Yeast extract (YE), a nutritious and sustainable food ingredient, primarily functions as a food flavor enhancer and bioactive ingredient in the food industry. Currently, there is a dearth of systematic reviews on the taste-active and bioactive activities of YE. This review provides a comprehensive review of preparation methods, taste-active and bioactive activities of YE as well as their applications in the food sector. Furthermore, the challenges and future perspectives of YE are discussed. YE can be obtained through the degradation and removal of yeast cell walls. Its extraction can be achieved through various methods, including physical, autolytic, enzymatic, and cell wall disruption techniques. YE comprises a range of components, including glucan, mannan, proteins, phospholipids, minerals, vitamins, and various functional factors. These components collectively contribute to its diverse bioactivities, such as antioxidant, ACE-inhibitory, antibacterial, immunomodulatory, diuretic and sedative effects. Furthermore, YE contains taste-active substances and aroma-active compounds, making it promising as a flavor enhancer. It is potent bioactivity also makes it applicable in the food and nutraceutical industries.

酵母提取物(YE)是一种营养丰富、可持续发展的食品原料,在食品工业中主要用作食品增味剂和生物活性成分。目前,对叶黄素的味觉活性和生物活性缺乏系统的综述。本文综述了叶提取物的制备方法、风味活性和生物活性及其在食品领域的应用。此外,本文还讨论了人工智能面临的挑战和未来的发展前景。YE可以通过降解和去除酵母细胞壁来获得。它的提取可以通过各种方法实现,包括物理、自溶、酶和细胞壁破坏技术。YE包含一系列成分,包括葡聚糖、甘露聚糖、蛋白质、磷脂、矿物质、维生素和各种功能因子。这些成分共同有助于其多种生物活性,如抗氧化,ace抑制,抗菌,免疫调节,利尿和镇静作用。此外,叶黄还含有味活性物质和芳香活性化合物,是一种很有前景的增味剂。其强大的生物活性也使其适用于食品和营养保健工业。
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引用次数: 0
Food spoilage fungi: Main agents, sources and strategies for control. 食品腐败真菌:主要病原、来源及防治策略。
Q1 Agricultural and Biological Sciences Pub Date : 2025-01-01 Epub Date: 2024-10-28 DOI: 10.1016/bs.afnr.2024.09.011
M V Copetti, A O Bernardi, M V Garcia

Fungal spoilage poses significant challenges in the global food industry, affecting various types of food products. Certain foods are inherently more susceptible to fungal contamination due to their intrinsic characteristics, as well as both raw materials and the processing environment, particularly the air, serve as major sources of fungal spores. Once a product is contaminated, the ability of fungal species to overcome technological barriers imposed by the industry (such as preservatives, reduced water activity, low pH, storage temperature, and oxygen restriction) will determine the extent of spoilage. Implementing stringent hygiene procedures, focusing on selecting sanitizers with antifungal properties, can help reduce the fungal spore load in the production environment. This, in turn, can limit the number of spores that reach the food, thereby delaying spoilage. This contribution covers the fungi responsible for spoilage of a variety of food types as well as the dynamics involved in the product contamination, physiological adaptations to spoil specific food niches and main control measures, with focus in sanitizers.

真菌腐败是全球食品工业面临的重大挑战,影响着各种类型的食品。由于某些食品本身的特性,它们本身就更容易受到真菌污染,而且原材料和加工环境,特别是空气,都是真菌孢子的主要来源。一旦产品被污染,真菌物种克服行业技术障碍的能力(如防腐剂、水活度降低、低pH值、储存温度和限氧)将决定腐败的程度。实施严格的卫生程序,重点选择具有抗真菌特性的消毒剂,可以帮助减少生产环境中的真菌孢子负荷。这反过来又可以限制到达食物的孢子数量,从而延缓变质。这一贡献涵盖了负责各种食品类型的腐败的真菌,以及涉及产品污染的动态,破坏特定食品生态位的生理适应和主要控制措施,重点是消毒剂。
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引用次数: 0
Metabolomics advances in understanding phenolic compound variability in cereals and their nutritional impacts. 代谢组学在了解谷类酚类化合物变异及其营养影响方面取得进展。
Q1 Agricultural and Biological Sciences Pub Date : 2025-01-01 Epub Date: 2025-07-29 DOI: 10.1016/bs.afnr.2025.07.004
Deepika Kathuria, Narpinder Singh

Cereals play a crucial role in global food security and economic development, serving as primary sources of energy, dietary fiber, and bioactive compounds. In addition to their macronutrient content, cereals are rich in phenolic compounds, including flavonoids and phenolic acids, which contribute to their nutritional and functional properties. However, the composition of these bioactive compounds is influenced by genetic factors, environmental conditions, and processing methods. Metabolomics, an advanced analytical approach, has emerged as a powerful tool for exploring the metabolic variability of cereals. Techniques such as Gas Chromatography-Time-of-Flight Mass Spectrometry (GC-TOF-MS) and Liquid Chromatography-Quadrupole Time-of-Flight Mass Spectrometry (LC-QTOF-MS/MS) enable the identification and quantification of diverse phenolic compounds, providing insights into their complexity and dynamics. Moreover, metabolomics has facilitated the identification of phenolic biomarkers in humans, linking dietary phenolics to potential health benefits, including reduced risks of chronic diseases such as cardiovascular disorders, diabetes, and cancer. The present chapter discuss the role of metabolomics in understanding phenolic compound variability in cereals, highlighting changes in metabolic profiles during crop development and processing. Additionally, it explores the implications of cereal-derived phenolics in promoting human health, emphasizing their significance in the development of functional foods. The advancements in metabolomics continue to drive innovation in cereal-based products, offering new opportunities for enhancing their nutritional and health-promoting properties.

谷物作为能源、膳食纤维和生物活性化合物的主要来源,在全球粮食安全和经济发展中发挥着至关重要的作用。除了常量营养素外,谷物还富含酚类化合物,包括类黄酮和酚酸,这有助于它们的营养和功能特性。然而,这些生物活性化合物的组成受到遗传因素、环境条件和加工方法的影响。代谢组学是一种先进的分析方法,已成为探索谷物代谢变异性的有力工具。气相色谱-飞行时间质谱(GC-TOF-MS)和液相色谱-四极杆飞行时间质谱(LC-QTOF-MS/MS)等技术能够识别和定量各种酚类化合物,从而深入了解其复杂性和动态。此外,代谢组学促进了人类酚类生物标志物的鉴定,将膳食酚类物质与潜在的健康益处联系起来,包括降低心血管疾病、糖尿病和癌症等慢性疾病的风险。本章讨论代谢组学在理解谷物酚类化合物变异中的作用,重点介绍作物发育和加工过程中代谢谱的变化。此外,它探讨了谷物衍生的酚类物质在促进人体健康方面的意义,强调了它们在功能食品开发中的重要性。代谢组学的进步继续推动谷物产品的创新,为增强其营养和促进健康的特性提供了新的机会。
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引用次数: 0
Lipid Oxidation in Meat: From Fundamental Mechanisms to Latest Control Solutions. 肉中的脂质氧化:从基本机制到最新的控制解决方案。
Q1 Agricultural and Biological Sciences Pub Date : 2025-01-01 Epub Date: 2025-05-12 DOI: 10.1016/bs.afnr.2025.04.005
Wei Luo, Jingnan Zhang, Haizhou Wu

Lipid oxidation remains one of the most critical pathways compromising the quality and shelf life of meat and meat products. Over the past three decades, significant advances have been made in elucidating the mechanisms of lipid oxidation and in developing both experimental and computational approaches to study and control these processes. This chapter provides a comprehensive overview of these approaches, detailing their relative strengths and limitations. The complex interplay between substrates (e.g., unsaturated fatty acids) and pro-oxidant factors (e.g., heme pigments, lipoxygenase, iron) is thoroughly examined to offer an updated perspective on oxidation pathways in real-world muscle food systems. In addition, current knowledge gaps and challenges are highlighted to inspire further research. A major focus is placed on antioxidant strategies, from established synthetic additives to novel natural compounds, and the mechanistic basis for their protective effects. Selected industrial case studies illustrate successful implementations of these antioxidants, emphasizing sustainability. The chapter concludes by highlighting the importance of interdisciplinary collaboration, incorporating insights from chemistry, biology, engineering, and related fields. Such cross-disciplinary efforts, supported by emerging research concepts and technologies, will be critical for developing innovative solutions that advance our understanding of lipid oxidation mechanisms and enhance oxidation control in meat and meat products.

脂质氧化仍然是影响肉类和肉制品质量和保质期的最关键途径之一。在过去的三十年中,在阐明脂质氧化的机制以及发展实验和计算方法来研究和控制这些过程方面取得了重大进展。本章提供了这些方法的全面概述,详细说明了它们的相对优势和局限性。底物(如不饱和脂肪酸)和促氧化因子(如血红素色素、脂氧合酶、铁)之间复杂的相互作用进行了彻底的研究,为现实世界肌肉食物系统中的氧化途径提供了新的视角。此外,强调了当前的知识差距和挑战,以激发进一步的研究。主要的焦点放在抗氧化策略上,从已建立的合成添加剂到新的天然化合物,以及它们保护作用的机制基础。选定的工业案例研究说明了这些抗氧化剂的成功实施,强调了可持续性。本章最后强调了跨学科合作的重要性,结合了化学、生物学、工程学和相关领域的见解。这种跨学科的努力,在新兴研究概念和技术的支持下,将对开发创新的解决方案至关重要,这些解决方案将促进我们对脂质氧化机制的理解,并加强肉类和肉制品中的氧化控制。
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引用次数: 0
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Advances in Food and Nutrition Research
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