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Virtualization and digital twins of the food supply chain for enhanced food safety. 食品供应链的虚拟化和数字双胞胎,以加强食品安全。
Q1 Agricultural and Biological Sciences Pub Date : 2024-01-01 Epub Date: 2024-06-18 DOI: 10.1016/bs.afnr.2024.06.001
Maria G Corradini, Angie K Homez-Jara, Chang Chen

Meeting food safety requirements without jeopardizing quality attributes or sustainability involves adopting a holistic perspective of food products, their manufacturing processes and their storage and distribution practices. The virtualization of the food supply chain offers opportunities to evaluate, simulate, and predict challenges and mishaps potentially contributing to present and future food safety risks. Food systems virtualization poses several requirements: (1) a comprehensive framework composed of instrumental, digital, and computational methods to evaluate internal and external factors that impact food safety; (2) nondestructive and real-time sensing methods, such as spectroscopic-based techniques, to facilitate mapping and tracking food safety and quality indicators; (3) a dynamic platform supported by the Internet of Things (IoT) interconnectivity to integrate information, perform online data analysis and exchange information on product history, outbreaks, exposure to risky situations, etc.; and (4) comprehensive and complementary mathematical modeling techniques (including but not limited to chemical reactions and microbial inactivation and growth kinetics) based on extensive data sets to make realistic simulations and predictions possible. Despite current limitations in data integration and technical skills for virtualization to reach its full potential, its increasing adoption as an interactive and dynamic tool for food systems evaluation can improve resource utilization and rational design of products, processes and logistics for enhanced food safety. Virtualization offers affordable and reliable options to assist stakeholders in decision-making and personnel training. This chapter focuses on definitions and requirements for developing and applying virtual food systems, including digital twins, and their role and future trends in enhancing food safety.

要在不损害质量属性或可持续性的情况下满足食品安全要求,就必须对食品、其制造过程及其储存和分销做法采取全面的视角。食品供应链的虚拟化为评估、模拟和预测可能导致当前和未来食品安全风险的挑战和事故提供了机会。食品系统虚拟化提出了若干要求:(1) 由工具、数字和计算方法组成的综合框架,以评估影响食品安全的内部和外部因素;(2) 无损和实时传感方法,如基于光谱的技术,以促进绘制和跟踪食品安全和质量指标;(3) 由物联网(IoT)互联支持的动态平台,以整合信息,执行在线数据分析,并交换有关产品历史、疫情爆发、暴露于风险情况等方面的信息;(4) 综合和互补的食品安全系统。(4) 基于大量数据集的全面、互补的数学建模技术(包括但不限于化学反应、微生物失活和生长动力学),以便进行逼真的模拟和预测。尽管目前在数据整合和技术技能方面存在限制,虚拟化无法充分发挥其潜力,但作为食品系统评估的互动和动态工具,虚拟化的应用日益广泛,可以提高资源利用率,合理设计产品、工艺和物流,从而提高食品安全。虚拟化为协助利益相关者进行决策和人员培训提供了经济可靠的选择。本章重点介绍开发和应用虚拟食品系统(包括数字孪生)的定义和要求,以及它们在加强食品安全方面的作用和未来趋势。
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引用次数: 0
Diabetes and vitamin D: The effect of insulin sensitivity and gut microbial health. 糖尿病与维生素 D:胰岛素敏感性和肠道微生物健康的影响。
Q1 Agricultural and Biological Sciences Pub Date : 2024-01-01 Epub Date: 2024-04-20 DOI: 10.1016/bs.afnr.2024.04.001
Denise K Daley, Semone B Myrie

Current global estimation suggests that about 10% of adults worldwide have diabetes, thus, various strategies are needed to address the issue, including dietary factors such as vitamin D. Various studies have suggested an inverse associations between vitamin D and the risks and pathogenesis of all forms of diabetes (type 1, type 2 and gestational diabetes). The underlying mechanism is not fully understood; however, the expression of vitamin D receptors in pancreatic beta cells suggests an important physiological role for vitamin D in beta cell function. Vitamin D deficiency may impair blood glucose control and decrease insulin sensitivity by reducing insulin secretion from beta cells. Many studies suggest that vitamin D intervention may be beneficial; however, there is inconclusive evidence of the effectiveness of vitamin D supplementation on reducing the risks or managing the pathogenesis of all forms of diabetes. Part of the pathogenesis of vitamin D for reducing diabetes is thought to be related to its impact on gut microbiota profile, via the suggested prebiotic properties of vitamin D.

据目前的全球估计,全世界约有 10%的成年人患有糖尿病,因此需要采取各种策略来解决这一问题,包括饮食因素,如维生素 D。然而,胰岛β细胞中维生素 D 受体的表达表明,维生素 D 在β细胞功能中发挥着重要的生理作用。缺乏维生素 D 可能会损害血糖控制,并通过减少 beta 细胞分泌胰岛素而降低胰岛素敏感性。许多研究表明,维生素 D 的干预可能是有益的;然而,关于补充维生素 D 对降低各种糖尿病风险或控制其发病机制的有效性,目前尚无定论。维生素 D 减少糖尿病的部分发病机制被认为与维生素 D 的益生特性对肠道微生物群谱的影响有关。
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引用次数: 0
Future development trend of food-borne delivery systems of functional substances for precision nutrition. 用于精准营养的食源性功能物质输送系统的未来发展趋势。
Q1 Agricultural and Biological Sciences Pub Date : 2024-01-01 Epub Date: 2024-06-15 DOI: 10.1016/bs.afnr.2024.05.007
Shuwei Luo, Juntao Zhang, Jing Sun, Tong Zhao, Jianjun Deng, Haixia Yang

Background: Precision nutrition, a personalized nutritional supplementation model, is widely acknowledged for its significant impact on human health. Nevertheless, challenges persist in the advancement of precision nutrition, including consumer dietary behaviors, nutrient absorption, and utilization. Thus, the exploration of effective strategies to enhance the efficacy of precision nutrition and maximize its potential benefits in dietary interventions and disease management is imperative.

Scope and approach: The primary objective of this comprehensive review is to synthesize and assess the latest technical approaches and future prospects for achieving precision nutrition, while also addressing the existing constraints in this field. The role of delivery systems is pivotal in the realization of precision nutrition goals. This paper outlines the potential applications of delivery systems in precision nutrition and highlights key considerations for their design and implementation. Additionally, the review offers insights into the evolving trends in delivery systems for precision nutrition, particularly in the realms of nutritional fortification, specialized diets, and disease prevention.

Key findings and conclusions: By leveraging computer data collection, omics, and metabolomics analyses, this review scrutinizes the lifestyles, dietary patterns, and health statuses of diverse organisms. Subsequently, tailored nutrient supplementation programs are devised based on individual organism profiles. The utilization of delivery systems enhances the bioavailability of functional compounds and enables targeted delivery to specific body regions, thereby catering to the distinct nutritional requirements and disease prevention needs of consumers, with a particular emphasis on special populations and dietary preferences.

背景:精准营养是一种个性化的营养补充模式,因其对人类健康的重大影响而得到广泛认可。然而,在推进精准营养的过程中仍然存在挑战,包括消费者的饮食行为、营养素的吸收和利用。因此,探索有效策略以提高精准营养的功效并最大限度地发挥其在膳食干预和疾病管理方面的潜在益处势在必行:本综述的主要目的是综合评估实现精准营养的最新技术方法和未来前景,同时解决该领域的现有制约因素。在实现精准营养目标的过程中,传输系统的作用举足轻重。本文概述了输送系统在精准营养中的潜在应用,并强调了设计和实施输送系统的主要考虑因素。此外,这篇综述还深入分析了精准营养递送系统不断发展的趋势,特别是在营养强化、特殊膳食和疾病预防等领域:通过利用计算机数据收集、omics 和代谢组学分析,本综述仔细研究了不同生物体的生活方式、饮食模式和健康状况。随后,根据生物体的个体特征,设计出量身定制的营养补充方案。输送系统的利用提高了功能化合物的生物利用率,并实现了向特定身体区域的定向输送,从而满足了消费者不同的营养需求和疾病预防需求,特别强调了特殊人群和饮食偏好。
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引用次数: 0
Microgel delivery systems of functional substances for precision nutrition. 用于精准营养的功能物质微凝胶输送系统。
Q1 Agricultural and Biological Sciences Pub Date : 2024-01-01 Epub Date: 2024-06-18 DOI: 10.1016/bs.afnr.2024.05.003
Shanshan Tie

Microgels delivery system have great potential in functional substances encapsulation, protection, release, precise delivery and nutritional intervention. Microgel is a three-dimensional network structure formed by physical or chemical crosslinking of biopolymers, whose characteristics include dispersion and swelling, stable structure, small volume and high specific surface area, and is a special kind of colloid. In this chapter, the common wall materials for preparing food grade microgels, and the main preparation principles, methods, advantages and disadvantages of microgels loaded with functional substances were firstly reviewed. Then the main characteristics of microgel as delivery system, such as deformability, high encapsulation, stimulus-responsive release and targeted delivery, and its potential benefits in intervening chronic diseases were summarized. Finally, the applications of microgel delivery system for functional substance in the field of precision nutrition were discussed. This chapter will help to design of next-generation advanced targeting microgel delivery system, and realize precision nutrition intervention of food functional substances on body health.

微凝胶给药系统在功能性物质封装、保护、释放、精准给药和营养干预等方面具有巨大潜力。微凝胶是生物聚合物通过物理或化学交联形成的三维网络结构,具有分散溶胀、结构稳定、体积小、比表面积高等特点,是一种特殊的胶体。本章首先综述了制备食品级微凝胶的常用壁材,以及负载功能性物质的微凝胶的主要制备原理、方法和优缺点。然后,总结了微凝胶作为给药系统的主要特点,如变形性、高包裹性、刺激响应释放和靶向给药,以及其在干预慢性疾病方面的潜在益处。最后,讨论了功能物质微凝胶递送系统在精准营养领域的应用。本章将有助于设计下一代先进的靶向微凝胶递送系统,实现食品功能物质对人体健康的精准营养干预。
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引用次数: 0
Biological activity, limitations and steady-state delivery of functional substances for precision nutrition. 用于精准营养的功能物质的生物活性、局限性和稳态输送。
Q1 Agricultural and Biological Sciences Pub Date : 2024-01-01 Epub Date: 2024-06-15 DOI: 10.1016/bs.afnr.2024.05.006
Guoxin Cui, Xiaoting Yu, Ming He, Shasha Huang, Kangjing Liu, Yu Li, Jiaxuan Li, Xiaoyang Shao, Qiyan Lv, Xueqian Li, Mingqian Tan

Food-related functional substances with biological activity serve as a crucial material foundation for achieving precision nutrition, which has gained increasing attraction in regulating physiological functions, preventing chronic diseases, and maintaining human health. Nutritional substances typically include bioactive proteins, peptides, polysaccharides, polyphenols, functional lipids, carotenoids, probiotics, vitamins, saponins, and terpenes. These functional substances play an essential role in precise nutrition. This chapter introduces and summarizes typical functional substances to demonstrate the challenges in precision nutrition for their stability, solubility, and bioavailability. The current status of delivery systems of functional substances is described to give an insight into the development of desirable characteristics, such as food grade status, high loading capacity, site targeting, and controlled release capacity. Finally, the applications of food-borne delivery systems of functional substances for precision nutrition are emphasized to meet the requirement for precision nutrition during nutritional intervention for chronic diseases.

具有生物活性的食品相关功能物质是实现精准营养的重要物质基础,在调节生理机能、预防慢性疾病和维护人类健康方面的吸引力与日俱增。营养物质通常包括生物活性蛋白质、肽、多糖、多酚、功能脂类、类胡萝卜素、益生菌、维生素、皂苷和萜类化合物。这些功能性物质在精准营养中发挥着重要作用。本章介绍并总结了典型的功能物质,以说明精准营养在稳定性、溶解性和生物利用度方面所面临的挑战。本章还介绍了功能物质递送系统的现状,以便深入了解食品级状态、高负载能力、靶点定位和控释能力等理想特性的发展。最后,强调了功能物质食源性给药系统在精准营养方面的应用,以满足慢性病营养干预过程中对精准营养的要求。
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引用次数: 0
High pressure processing plus technologies: Enhancing the inactivation of vegetative microorganisms. 高压加工加技术:加强无性微生物的灭活。
Q1 Agricultural and Biological Sciences Pub Date : 2024-01-01 Epub Date: 2024-05-31 DOI: 10.1016/bs.afnr.2024.02.003
Peiqing Yang, Xiaojun Liao

High pressure processing (HPP) is a non-thermal technology that can ensure microbial safety without compromising food quality. However, the presence of pressure-resistant sub-populations, the revival of sub-lethally injured (SLI) cells, and the resuscitation of viable but non-culturable (VBNC) cells pose challenges for its further development. The combination of HPP with other methods such as moderate temperatures, low pH, and natural antimicrobials (e.g., bacteriocins, lactate, reuterin, endolysin, lactoferrin, lactoperoxidase system, chitosan, essential oils) or other non-thermal processes (e.g., CO2, UV-TiO2 photocatalysis, ultrasound, pulsed electric fields, ultrafiltration) offers feasible alternatives to enhance microbial inactivation, termed as "HPP plus" technologies. These combinations can effectively eliminate pressure-resistant sub-populations, reduce SLI or VBNC cell populations, and inhibit their revival or resuscitation. This review provides an updated overview of microbial inactivation by "HPP plus" technologies and elucidates possible inactivation mechanisms.

高压处理(HPP)是一种非热处理技术,可在不影响食品质量的情况下确保微生物安全。然而,抗压亚群的存在、亚致死损伤(SLI)细胞的复苏以及可存活但不可培养(VBNC)细胞的复苏都对其进一步发展提出了挑战。HPP 与其他方法的结合,如适度温度、低 pH 值、天然抗菌剂(如细菌素、乳酸、芦丁素、内溶血素、乳铁蛋白、乳过氧化物酶系统、壳聚糖、精油)或其他非热过程(如二氧化碳、UV-TiO2 光催化、超声波、脉冲电场、超滤),为加强微生物灭活提供了可行的替代方法,被称为 "HPP 加 "技术。这些组合可有效消除耐压亚群,减少 SLI 或 VBNC 细胞群,并抑制其复活或复苏。本综述概述了 "HPP+"技术灭活微生物的最新情况,并阐明了可能的灭活机制。
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引用次数: 0
Edible insects in food. 食物中的食用昆虫
Q1 Agricultural and Biological Sciences Pub Date : 2024-01-01 Epub Date: 2023-11-13 DOI: 10.1016/bs.afnr.2023.10.005
Yun-Sang Choi, Jae Hoon Lee, Tae-Kyung Kim, Dong-Min Shin

Edible insects, with their high protein and lipid content, offer a safe and cost-effective alternative to traditional protein sources. They are environmentally friendly, emitting fewer greenhouse gases and requiring less water than livestock farming. Their rapid reproduction, efficiency, and labor-saving qualities make them attractive for industry. However, the unappealing appearance of edible insects hinders consumer acceptance. To overcome this, materialization technologies should be developed, and negative perceptions addressed with objective data. Promoting the nutritional value, safe rearing, disease prevention, and cost-efficiency of edible insects can boost consumer interest. Commercializing various insect products is crucial to revitalize their integration into the food industry.

食用昆虫的蛋白质和脂质含量很高,是传统蛋白质来源的一种安全且具有成本效益的替代品。与畜牧业相比,它们对环境友好,排放的温室气体更少,需要的水也更少。昆虫繁殖快、效率高、省力,这些特点对工业具有吸引力。然而,可食用昆虫外表不美观,阻碍了消费者的接受。为克服这一问题,应开发物化技术,并通过客观数据消除负面看法。宣传食用昆虫的营养价值、安全饲养、疾病预防和成本效益,可以提高消费者的兴趣。各种昆虫产品的商业化对其重新融入食品工业至关重要。
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引用次数: 0
Upcycling of seafood side streams for circularity. 海产品副产品的循环再利用。
Q1 Agricultural and Biological Sciences Pub Date : 2024-01-01 Epub Date: 2024-02-13 DOI: 10.1016/bs.afnr.2023.11.002
R Anbarasan, Brijesh K Tiwari, R Mahendran

The upcycling of seafood side streams emerges as a crucial facet in the quest for circularity within the food industry, surpassing other food sources in its significance. Seafood side stream plays an indispensable role in global food security and human nutrition. Nevertheless, losses ensue throughout the seafood supply chain, resulting in substantial waste generation. These underutilized seafood by-products contain valuable resources like edible proteins and nitrogenous compounds. Projections indicate that fishery products' utilization for human consumption will soar to 204 MT by 2030. Yet, the industry annually generates millions of tonnes of waste, predominantly from crab, shrimp, and lobster shells, leading to environmental impacts due to COD and BOD issues. A five-tier circular economic model offers a framework to manage seafood side-streams efficiently, with applications spanning pharmaceuticals, food production, animal feed, fertilizers, and energy fuel, thereby maximizing their potential and reducing waste in line with sustainability goals.

海产品副产品的升级再循环是食品工业追求循环性的一个重要方面,其重要性超过了其他食品来源。海产品副产品在全球粮食安全和人类营养方面发挥着不可或缺的作用。然而,在整个海产品供应链中,损失接踵而至,产生了大量废物。这些未得到充分利用的海产品副产品含有可食用蛋白质和含氮化合物等宝贵资源。据预测,到 2030 年,用于人类消费的水产品将飙升至 204 公吨。然而,该行业每年产生数百万吨废物,主要来自螃蟹、虾和龙虾壳,由于化学需氧量和生化需氧量问题而对环境造成影响。五层循环经济模型为有效管理海产品副产品提供了一个框架,其应用范围涵盖制药、食品生产、动物饲料、肥料和能源燃料,从而最大限度地发挥其潜力,减少浪费,实现可持续发展目标。
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引用次数: 0
Vitamin D and obesity. 维生素 D 与肥胖症
Q1 Agricultural and Biological Sciences Pub Date : 2024-01-01 Epub Date: 2024-03-05 DOI: 10.1016/bs.afnr.2023.12.006
Chan Yoon Park, Sung Nim Han

An inverse association between vitamin D status and obesity has been reported across diverse populations and age groups in humans. In animal model of diet-induced obesity, dysregulation of vitamin D metabolism has been observed. However, the causal relationship between vitamin D status and obesity is not conclusive. Several explanations, such as volumetric dilution, sequestration of vitamin D into adipose tissue, and limited sunlight exposure, have been suggested as the underlying mechanisms linking poor vitamin D status and obesity. Vitamin D can modulate adipose tissue biology, spanning from adipocyte differentiation to adipocyte apoptosis and energy metabolism, indicating its potential impact on adiposity. In this chapter, we will review the prevalence of vitamin D deficiency and determinants of vitamin D deficiency among different populations, as well as changes in vitamin D metabolism associated with obesity. Additionally, we will review vitamin D's regulation of adipogenesis and lipogenesis at the cellular level in order to gain a deeper understanding of the underlying mechanisms linking vitamin D levels and obesity.

据报道,在不同人群和年龄组中,维生素 D 状态与肥胖之间存在反向关系。在饮食诱发肥胖的动物模型中,已观察到维生素 D 代谢失调。然而,维生素 D 状态与肥胖之间的因果关系尚无定论。有几种解释,如体积稀释、维生素 D 被螯合到脂肪组织中、有限的阳光照射,被认为是维生素 D 状态不佳与肥胖之间的内在机制。维生素 D 可调节脂肪组织的生物学特性,包括脂肪细胞分化、脂肪细胞凋亡和能量代谢,这表明它对肥胖具有潜在影响。在本章中,我们将回顾维生素 D 缺乏症在不同人群中的发病率和决定因素,以及与肥胖相关的维生素 D 代谢变化。此外,我们还将回顾维生素 D 在细胞水平上对脂肪生成和脂肪生成的调节作用,以便更深入地了解维生素 D 水平与肥胖之间的内在联系。
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引用次数: 0
Frontiers of machine learning in smart food safety. 智能食品安全领域的机器学习前沿。
Q1 Agricultural and Biological Sciences Pub Date : 2024-01-01 Epub Date: 2024-06-22 DOI: 10.1016/bs.afnr.2024.06.009
Jinxin Liu, Jessica Bensimon, Xiaonan Lu

Integration of machine learning (ML) technologies into the realm of smart food safety represents a rapidly evolving field with significant potential to transform the management and assurance of food quality and safety. This chapter will discuss the capabilities of ML across different segments of the food supply chain, encompassing pre-harvest agricultural activities to post-harvest processes and delivery to the consumers. Three specific examples of applying cutting-edge ML to advance food science are detailed in this chapter, including its use to improve beer flavor, using natural language processing to predict food safety incidents, and leveraging social media to detect foodborne disease outbreaks. Despite advances in both theory and practice, application of ML to smart food safety still suffers from issues such as data availability, model reliability, and transparency. Solving these problems can help realize the full potential of ML in food safety. Development of ML in smart food safety is also driven by social and industry impacts. The improvement and implementation of legal policies brings both opportunities and challenges. The future of smart food safety lies in the strategic implementation of ML technologies, navigating social and industry impacts, and adapting to regulatory changes in the AI era.

将机器学习(ML)技术融入智能食品安全领域是一个快速发展的领域,具有改变食品质量与安全管理和保证的巨大潜力。本章将讨论 ML 在食品供应链不同环节的能力,包括收获前的农业活动、收获后的流程以及向消费者的交付。本章将详细介绍应用尖端 ML 推动食品科学发展的三个具体实例,包括使用 ML 改善啤酒风味、使用自然语言处理预测食品安全事件,以及利用社交媒体检测食源性疾病爆发。尽管在理论和实践方面都取得了进步,但将 ML 应用于智能食品安全仍存在数据可用性、模型可靠性和透明度等问题。解决这些问题有助于充分发挥 ML 在食品安全领域的潜力。智能食品安全领域的 ML 发展还受到社会和行业影响的推动。法律政策的完善和实施既带来了机遇,也带来了挑战。智能食品安全的未来取决于如何战略性地实施 ML 技术、驾驭社会和行业影响以及适应人工智能时代的监管变化。
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引用次数: 0
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