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Neurosarcoidosis From Pituitary Expansion to Empty Sella 从垂体扩张到空蝶鞍的神经结节病
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.25270/con.2022.07.000015
G. Thota, Yelizaveta Gribkova, R. Desai
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引用次数: 0
A Case of Oral Valacyclovir–Induced Acute Kidney Injury 口服伐昔洛韦致急性肾损伤1例
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.25270/con.2022.07.000016
G. Thota, Mehak Bassi, Niraj Nagaraj Ballam
Acute kidney injury (AKI) is defined as a rapid reduction in kidney function (within 48 hours) as measured by an increase in serum creatinine level, decrease in urine output, or need for renal replacement therapy, or all of the above. Herein, we present a rare case of AKI induced by oral valacyclovir. Nephrotoxicity due to valacyclovir is caused by intratubular precipitation of acyclovir crystals. A 39-year-old woman presents with acute onset of nonspecific reports of low back pain, nausea, and vomiting. After determining there was an AKI, the patient was treated with intravenous fluids and was monitored for improvement. The cause was deduced to be oral valacyclovir, which was being used to treat herpes labialis, and ultimately caused crystal-induced nephrotoxicity. Due to the rapid speed of renal excretion, acyclovir can surpass the solubility, and hence crystals can accumulate in the distal and collecting ducts. This can cause the symp-tomatology such as in this patient. In this case presentation and discussion, we re-view the presenting symptoms, diagnostic testing, differentials, and pathophysiology regarding crystal-induced AKI, specifically from valacyclovir.
急性肾损伤(AKI)被定义为肾功能迅速下降(48小时内),表现为血清肌酐水平升高,尿量减少,或需要肾脏替代治疗,或以上所有情况。在此,我们报告一例罕见的口服伐昔洛韦引起的AKI。由阿昔洛韦引起的肾毒性是由阿昔洛韦晶体的小管内沉淀引起的。一名39岁女性以急性发作的非特异性报告腰痛、恶心和呕吐。在确定存在AKI后,患者接受静脉输液治疗并监测病情改善情况。原因被推断为口服valacyclovir,用于治疗唇疱疹,并最终导致晶体诱导肾毒性。由于肾脏排泄速度快,无环鸟苷可以超过溶解度,因此晶体可以积聚在远端和集合管中。这可能会导致像这个病人这样的症状。在本病例的介绍和讨论中,我们回顾了晶体诱导AKI的表现症状、诊断测试、鉴别和病理生理学,特别是伐昔洛韦。
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引用次数: 1
Acute Adrenal Crisis From Mental Stress in a Patient With Hypopituitarism 垂体功能减退症患者精神压力所致急性肾上腺危机1例
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.25270/con.2022.08.000001
Ryan C. Higgins, Madhavi Singh
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引用次数: 0
Sudden Hearing Loss Linked to Metastatic Adenocarcinoma of the Temporal Bone 突发性听力损失与颞骨转移性腺癌有关
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.25270/con.2022.08.000008
S. Hersh, Joshua Hersh, P. Gerard, Sana Ali
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引用次数: 0
Systemic Lupus Erythematosus in a 24-Year-Old 系统性红斑狼疮,24岁
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.25270/con.2022.08.000004
James J. Matera
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引用次数: 0
Telemedicine: The Future of Office Visits 远程医疗:办公室访问的未来
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.25270/con.2022.07.00008
Bensson Samuel, Carmine Mazzuca
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引用次数: 1
Weakness in the Upper Extremity After a Fall 跌倒后上肢无力
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.25270/con.2022.10.000003
M. Grover, Sethu Sandeep Koneru
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引用次数: 0
Oral Congenital Melanocytic Nevi: A Rare Finding 口腔先天性黑素细胞痣:罕见的发现
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.25270/con.2022.10.000004
Jesse D. Bracamonte, Michael Underhill, Denise Schweda
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引用次数: 0
Allergic Asthma Therapy and Management 过敏性哮喘的治疗和管理
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.25270/con.2022.11.000002
Daniel A Reich, Carols A. Arango
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引用次数: 0
Neurosyphilis in the Time of COVID-19: Avoiding Anchoring Heuristics COVID-19时期的神经梅毒:避免锚定启发式
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.25270/con.2022.11.000008
G. Thota, M. Shah, S. Chandna, Marnie E. Rosenthal
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引用次数: 0
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