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A Concerning Uvula Abnormality A关于小舌异常
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.25270/con.2022.01.00001
N. Lam, Patricia Campbell
A 21-year-old woman with no significant medical history presented to our clinic with “something hanging” from her uvula. She had noticed it a few months prior to presentation when she felt a tickling sensation at the back of her throat. At presentation, she said it now felt like it grew, because it was causing her to gag at times when swallowing. She denied any pain, difficulty swallowing, difficulty breathing, snoring, bleeding, or any changes in her voice. She is concerned because she believes her uvula is now connected to her tongue and is worried it may be cancerous. On physical examination, her vital signs were stable with 100% oxygen saturation on room air. Results of a head, eyes, ears, nose, and throat examination were normal except for the uvula abnormality. An oropharynx examination revealed a thin strand of tissue connecting the tip of her uvula to the base of her tongue (Figure). No cervical lymphadenopathy was noted, and the rest of her examination was unremarkable. Based on the patient’s history and physical examination, which one of the following is the most likely diagnosis?
一位21岁女性,无明显病史,因小舌“悬垂物”就诊。她在演讲前几个月就注意到了,当时她感到喉咙后部有一种发痒的感觉。在介绍时,她说现在感觉它变大了,因为它有时会让她在吞咽时呕吐。她否认有任何疼痛、吞咽困难、呼吸困难、打鼾、出血或声音变化。她很担心,因为她认为她的小舌现在与舌头相连,她担心小舌可能癌变了。经体格检查,她的生命体征稳定室内空气氧饱和度为100%。除小舌异常外,头、眼、耳、鼻、喉检查均正常。口咽部检查显示,小舌尖与舌底之间有一薄组织(图)。未见宫颈淋巴结病变,其余检查无明显异常。根据病人的病史和体格检查,下列哪一项是最有可能的诊断?
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引用次数: 0
Sudden Hearing Loss Linked to Metastatic Adenocarcinoma of the Temporal Bone 突发性听力损失与颞骨转移性腺癌有关
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.25270/con.2022.08.000008
S. Hersh, Joshua Hersh, P. Gerard, Sana Ali
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引用次数: 0
Intradermal Injection of Normal Saline for Treatment of Fat Atrophy Following Corticosteroid Injection 皮内注射生理盐水治疗皮质类固醇注射后脂肪萎缩
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.25270/con.2022.02.00008
Sierra Crowe, E. C. Schmidgal
A 20-year-old woman with a Fitzpatrick score of 2 presented via telehealth with “divots” on her forehead and scalp. She reported that 2 months prior to presentation she had received multiple steroid injections into her forehead and posterior skull by a neurologist for treatment of migraines. She had soon thereafter developed fat atrophy in 3 areas: 2 on her forehead and 1 on her occipital scalp. Although they were not painful or otherwise symptomatic, she was unhappy with the cosmetic appearance. She had no other skin or systemic symptoms. She visited the office the following day, and on examination, 2 atrophic plaques were noted on her bilateral forehead around the mid-pupillary lines, with a larger atrophic plaque on the occipital scalp (Figures 1 and 2). Given the location and timing of the lesions, they were consistent with skin atrophy induced by her prior steroid injections. Therefore, a biopsy was not performed.
一名20岁的女性,菲茨帕特里克得分为2分,通过远程医疗在她的前额和头皮上发现了“草皮”。她报告说,在就诊前2个月,她曾接受神经科医生多次在前额和后颅骨注射类固醇治疗偏头痛。此后不久,她的3个部位出现了脂肪萎缩:前额2个,枕部头皮1个。虽然没有疼痛或其他症状,但她对美容外观不满意。她没有其他皮肤或全身症状。第二天,患者就诊,检查发现双侧前额瞳孔中线周围有2个萎缩斑块,枕部头皮有较大萎缩斑块(图1和2)。考虑到病变的位置和时间,这与患者先前注射类固醇引起的皮肤萎缩一致。因此,没有进行活检。
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引用次数: 0
A Case of Oral Valacyclovir–Induced Acute Kidney Injury 口服伐昔洛韦致急性肾损伤1例
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.25270/con.2022.07.000016
G. Thota, Mehak Bassi, Niraj Nagaraj Ballam
Acute kidney injury (AKI) is defined as a rapid reduction in kidney function (within 48 hours) as measured by an increase in serum creatinine level, decrease in urine output, or need for renal replacement therapy, or all of the above. Herein, we present a rare case of AKI induced by oral valacyclovir. Nephrotoxicity due to valacyclovir is caused by intratubular precipitation of acyclovir crystals. A 39-year-old woman presents with acute onset of nonspecific reports of low back pain, nausea, and vomiting. After determining there was an AKI, the patient was treated with intravenous fluids and was monitored for improvement. The cause was deduced to be oral valacyclovir, which was being used to treat herpes labialis, and ultimately caused crystal-induced nephrotoxicity. Due to the rapid speed of renal excretion, acyclovir can surpass the solubility, and hence crystals can accumulate in the distal and collecting ducts. This can cause the symp-tomatology such as in this patient. In this case presentation and discussion, we re-view the presenting symptoms, diagnostic testing, differentials, and pathophysiology regarding crystal-induced AKI, specifically from valacyclovir.
急性肾损伤(AKI)被定义为肾功能迅速下降(48小时内),表现为血清肌酐水平升高,尿量减少,或需要肾脏替代治疗,或以上所有情况。在此,我们报告一例罕见的口服伐昔洛韦引起的AKI。由阿昔洛韦引起的肾毒性是由阿昔洛韦晶体的小管内沉淀引起的。一名39岁女性以急性发作的非特异性报告腰痛、恶心和呕吐。在确定存在AKI后,患者接受静脉输液治疗并监测病情改善情况。原因被推断为口服valacyclovir,用于治疗唇疱疹,并最终导致晶体诱导肾毒性。由于肾脏排泄速度快,无环鸟苷可以超过溶解度,因此晶体可以积聚在远端和集合管中。这可能会导致像这个病人这样的症状。在本病例的介绍和讨论中,我们回顾了晶体诱导AKI的表现症状、诊断测试、鉴别和病理生理学,特别是伐昔洛韦。
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引用次数: 1
Acute Adrenal Crisis From Mental Stress in a Patient With Hypopituitarism 垂体功能减退症患者精神压力所致急性肾上腺危机1例
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.25270/con.2022.08.000001
Ryan C. Higgins, Madhavi Singh
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引用次数: 0
Systemic Lupus Erythematosus in a 24-Year-Old 系统性红斑狼疮,24岁
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.25270/con.2022.08.000004
James J. Matera
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引用次数: 0
Weakness in the Upper Extremity After a Fall 跌倒后上肢无力
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.25270/con.2022.10.000003
M. Grover, Sethu Sandeep Koneru
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引用次数: 0
Oral Congenital Melanocytic Nevi: A Rare Finding 口腔先天性黑素细胞痣:罕见的发现
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.25270/con.2022.10.000004
Jesse D. Bracamonte, Michael Underhill, Denise Schweda
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引用次数: 0
Allergic Asthma Therapy and Management 过敏性哮喘的治疗和管理
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.25270/con.2022.11.000002
Daniel A Reich, Carols A. Arango
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引用次数: 0
Neurosyphilis in the Time of COVID-19: Avoiding Anchoring Heuristics COVID-19时期的神经梅毒:避免锚定启发式
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.25270/con.2022.11.000008
G. Thota, M. Shah, S. Chandna, Marnie E. Rosenthal
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引用次数: 0
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