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[Responses to "A Review of the Book 'Minamata Disease and the Responsibility of Medical Authorities'"]. [对"《水俣病与医疗机构的责任》一书的评论 "的回应]。
Q3 Medicine Pub Date : 2024-01-01 DOI: 10.1265/jjh.24005
Shigeru Takaoka

Drs. Futatsuka, Eto, and Uchino expressed their opinions in the Journal of the Japanese Society for Hygiene in the form of a review of my book, "Minamata Disease and the Responsibility of Medicine." (The reviewers translated it as "Responsibility of Medical Authorities," but for my purposes in writing this book, I believe it should be translated as "Responsibility of Medicine.") The nine major comments of the three reviewers described in this book review were reviewed from the basic perspective of toxicology, epidemiology, and neuroscience. This book review is fraught with either medical, logical, or ethical problems in all the nine points as follows: (1) the inadequate way in which exposure and health hazards are considered from the toxicological perspective, (2) problems in interpreting epidemiological information, (3) the failure to consider recent achievements in methylmercury toxicosis studies, (4) presenting the reviewers' own theories without regard to the content of my book while calling it a "book review," (5) presenting and criticizing what Takaoka does not claim as if he does, and (6) making claims that are inconsistent with the three reviewers' own views. The problems with this book review will become even clearer when you read "Minamata Disease and the Responsibility of Medicine" itself.

Futatsuka 博士、Eto 博士和 Uchino 博士在《日本卫生学会杂志》上以评论我的著作《水俣病与医学的责 任》的形式表达了他们的观点。(评论者将其翻译为 "医疗当局的责任",但出于写作本书的目的,我认为应翻译为 "医学的责任")。本书评从毒理学、流行病学和神经科学的基本角度对三位审稿人的九条主要意见进行了评述。这篇书评在以下九点上都存在着医学、逻辑或伦理方面的问题:(1)从毒理学角度考虑暴露和健康危害的方式不够充分;(2)在解释流行病学信息方面存在问题;(3)没有考虑到甲基汞中毒症研究的最新成果;(4)在称其为 "书评 "的同时,不顾我的书的内容,提出了评论者自己的理论;(5)把高冈没有提出的主张当作他提出的主张来提出和批评;(6)提出了与三位评论者自己的观点不一致的主张。阅读《水俣病与医学的责任》一书后,这篇书评的问题会更加明显。
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引用次数: 0
[To the memory of the late Dr. Akira Okada]. [纪念已故的冈田明博士]。
Q3 Medicine Pub Date : 2024-01-01 DOI: 10.1265/jjh.2024o1
Hiroyuki Nakamura
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引用次数: 0
[Reliability and validity of the Japanese version of the Pediatric Epilepsy Medication Self-Management Questionnaire Caregiver Version]. [日文版小儿癫痫用药自我管理问卷护理人员版的可靠性和有效性]。
Q3 Medicine Pub Date : 2024-01-01 DOI: 10.1265/jjh.24004
Mai Yamada, Tomoko Sumiyoshi, Nao Seki, Aya Saito, Makiko Tsubokawa

Objectives: The objectives of this study were to develop a Japanese version of the Pediatric Epilepsy Medication Self-Management Questionnaire Caregiver Version (PEMSQ-J) and to examine its reliability and validity.

Methods: A quantitative cross-sectional study was conducted among primary caregivers (N=309) of children under the age of 18 taking epilepsy medication. The PEMSQ-J was the main instrument used to collect information such as basic demographics.Cronbach's α was calculated to determine internal consistency, and the intraclass correlation coefficient was calculated to assess reproducibility. In addition, confirmatory factor analysis with covariance structure analysis was performed to confirm the goodness of fit of the model. Finally, criterion-related validity was confirmed.

Results: Analysis of responses to items on the PEMSQ-J revealed no ceiling or floor effects, and there was no marked bias in distributions in terms of skewness or kurtosis. Internal consistency assessed with Cronbach's α ranged from 0.847 to 0.935. A test of reproducibility revealed that the intraclass correlation for the total score was 0.730. Exploratory factor analysis identified two factors, which differed from the four factors in the original version. When their details and structure were examined, however, the two were interpreted as having a similar structure. Similarly to those of the original version, the goodness-of-fit indices for the four factors according to confirmatory factor analysis were close to the standard values.

Conclusion: The PEMSQ-J, which consists of 27 items with a four-factor structure, was statistically acceptable, and it was found to have a certain degree of reliability and validity.

研究目的本研究的目的是开发日语版儿科癫痫用药自我管理问卷照顾者版(PEMSQ-J),并检验其可靠性和有效性:对 18 岁以下服用癫痫药物儿童的主要照顾者(309 人)进行了一项定量横断面研究。PEMSQ-J 是用于收集基本人口统计学等信息的主要工具。计算 Cronbach's α 以确定内部一致性,计算类内相关系数以评估再现性。此外,还进行了带有协方差结构分析的确证因子分析,以确认模型的拟合度。最后,还确认了与标准相关的有效性:结果:对 PEMSQ-J 各项目回答的分析表明,没有出现上限或下限效应,在偏度或峰度分布方面也没有明显偏差。用 Cronbach's α 评估的内部一致性介于 0.847 和 0.935 之间。重现性测试显示,总分的类内相关为 0.730。探索性因子分析确定了两个因子,它们与原始版本中的四个因子有所不同。然而,在对其细节和结构进行研究时,这两个因子被解释为具有相似的结构。与原始版本相似,确认性因子分析得出的四个因子的拟合优度指数也接近标准值:结论:PEMSQ-J 由 27 个项目组成,具有四因素结构,在统计学上可以接受,并具有一定的信度和效度。
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引用次数: 0
[Awareness of issues in research and educational activities and expectations for young researchers' activities and supporting]. [对研究和教育活动中的问题的认识以及对青年研究人员活动和支持的期望]。
Q3 Medicine Pub Date : 2024-01-01 DOI: 10.1265/jjh.23006
Xi Lu, Tomoko Fujitani, Midori Takeda, Wataru Miyazaki, Takamitsu Miyayama, Masamitsu Eitoku, Akira Minoura

Objectives: To understand the actual situation and needs of young researchers and to provide reference for the management of Young Researchers Association (YRA) and the Japanese Society for Hygiene activities in the future.

Methods: An Internet survey was conducted on 67 members registered in YRA of the Japanese Society for Hygiene. The questions included those on basic information, research content and impressions about the activities of the society.

Results: Although members of YRA differ in backgrounds, research method used, and years of research experience, the respondents rated the organization as highly useful and participated continuously. In particular, they considered that participation in the planning of academic conferences and summer gatherings of YRA not only helped improve interpersonal relationships and expertise, but also provided opportunities to consult regarding educational activities and collect information. Regarding the format of conferences, it was shown that the majority of requests were for a hybrid format. It was also shown that most of the respondents expected opportunities for collaboration and joint research through participation in YRA.

Conclusion: Through YRA, we would like to contribute to the further revitalization of young researchers and the Japanese Society for Hygiene by understanding and responding to the needs of diverse young researchers.

目的了解青年研究人员的实际情况和需求,为青年研究人员协会(YRA)和日本卫生学会今后的活动管理提供参考:对在日本卫生学会青年研究者协会注册的 67 名会员进行了网络调查。调查问题包括基本信息、研究内容和对学会活动的印象:尽管 YRA 会员的背景、使用的研究方法和研究年限各不相同,但受访者都认为该组织非常有用,并持续参与其中。特别是,他们认为参与青年研究会学术会议和暑期聚会的策划不仅有助于改善人际关系和专业知识,还提供了就教育活动进行咨询和收集信息的机会。关于会议的形式,大多数要求采用混合形式。结论:我们希望通过 YRA,了解和满足不同青年研究人员的需求,为进一步振兴青年研究人员和日本卫生学会做出贡献。
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引用次数: 0
[External Intervention for Visually Induced Postural Change during Video Viewing]. [视频观看过程中视觉诱发体位变化的外部干预]。
Q3 Medicine Pub Date : 2024-01-01 DOI: 10.1265/jjh.24001
Daisuke Nakajima, Yasuyuki Matsuura, Akihiro Sugiura, Takayuki Hirata, Hiroki Takada

Objectives: Virtual reality (VR) and three-dimensional (3D) images have become increasingly popular. It has been reported that visually induced motion sickness (VIMS) is more frequently caused by viewing these images. We propose a method to control VIMS by controlling visually evoked postural responses (VEPRs) using galvanic vestibular stimulation (GVS). In this study, we focused on the effect of VEPRs on body sway and conducted a transfer function analysis between the GVS and body sway. On the basis of the results of this investigation of the causes of VIMS, countermeasures must be considered.

Methods: The experiment involved 15 healthy young adults, comprising six males and nine females, all aged 21 years. The subjects were asked to maintain a Romberg posture while viewing an image that included a large number of randomly positioned moving spheres with their peripheral vision. In addition, body sway during GVS as an external stimulus was measured for 120s for each task.

Results: The transfer function analysis of the body sway showed that the influence on the equilibrium function was significantly enhanced not only by the GVS but even more so by viewing the video clips synchronized to the GVS.

Conclusions: GVS current signals induced body sway and increased the width of body sway synergistically. It was also suggested that a time delay structure occurred between the GVS current signal and body sway.

目标:虚拟现实(VR)和三维(3D)图像已经变得越来越流行。据报道,视动病(VIMS)更多是由观看这些图像引起的。我们提出了一种通过前庭电刺激(GVS)控制视觉诱发姿势反应(vepr)来控制VIMS的方法。在本研究中,我们重点研究了vepr对身体摇摆的影响,并进行了GVS与身体摇摆之间的传递函数分析。根据对VIMS产生原因的调查结果,必须考虑相应的对策。方法:实验对象为15名健康青年,男6名,女9名,年龄均为21岁。受试者被要求在观看包含大量随机定位的移动球体的图像时保持Romberg姿势。此外,在GVS期间作为外部刺激的身体摇摆在每个任务中测量120秒。结果:身体摇摆的传递函数分析表明,GVS对平衡函数的影响显著增强,而观看与GVS同步的视频片段对平衡函数的影响更大。结论:GVS电流信号具有诱导体摇摆和增加体摇摆宽度的协同作用。GVS电流信号与机体摇摆之间存在时滞结构。
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引用次数: 0
[Development of a Comprehensive Health Literacy Scale and Relationship between Health Literacy and Health-Related Behaviors among Japanese Workers]. [日本工人健康素养综合量表的开发及健康素养与健康相关行为之间的关系]。
Q3 Medicine Pub Date : 2024-01-01 DOI: 10.1265/jjh.23003
Keirin Nakadai, Junichi Kasamaki, Honoka Maruta

Objective: In this study, we aimed to develop a comprehensive health literacy (HL) scale for Japanese workers (CHLS-J) and to investigate the relationship between HL and health-related behaviors.

Methods: We conducted a cross-sectional study by a questionnaire survey of Japanese workers aged 18 years and older (N=313). The HL scale we previously developed was slightly modified on the basis of the pre-examination and used for developing CHLS-J. Self-reported data on demographic variables, socioeconomic status, health-related behaviors, present illness, past illness, and HL were collected. To determine the factor structure of the HL scale, an exploratory factor analysis was conducted, and the internal consistency of the scale was assessed using Cronbach's coefficient alpha. The criterion-related validity was evaluated using the Pearson product-moment correlation coefficient.

Results: From the results of factor analysis, 30 HL items were extracted and the structure was based on three factors (the knowledge and competencies for collecting health information, decision-making and communication, and the motivation for utilizing health information). High CHLS-J scores were significantly associated with food purchasing behaviors based on food labeling and maintaining a well-balanced diet. Furthermore, patients with present or past illness were more likely to have high CHLS-J scores.

Conclusions: The results show that CHLS-J is mostly a validated and reliable scale, and that the high-HL group had a healthy eating lifestyle. This study suggests that CHLS-J can be used to measure HL and educate Japanese workers on the necessity of health behavioral changes.

目的:本研究旨在为日本工人开发一个综合健康素养量表(CHLS-J),并调查健康素养与健康相关行为之间的关系:在这项研究中,我们旨在为日本工人开发一个综合健康素养量表(CHLS-J),并调查健康素养与健康相关行为之间的关系:我们通过问卷调查对 18 岁及以上的日本工人(313 人)进行了横断面研究。我们以前编制的 HL 量表在预调查的基础上稍作修改,用于编制 CHLS-J。调查收集了关于人口统计学变量、社会经济地位、健康相关行为、现病、既往病和 HL 的自我报告数据。为了确定 HL 量表的因子结构,我们进行了探索性因子分析,并使用 Cronbach's coefficient alpha 评估了量表的内部一致性。标准相关效度采用皮尔逊积矩相关系数进行评估:结果:从因子分析结果中提取了 30 个 HL 项目,其结构基于三个因子(收集健康信息的知识和能力、决策和沟通、利用健康信息的动机)。CHLS-J 的高分与根据食品标签购买食品和保持均衡饮食的行为明显相关。此外,现在或过去患有疾病的患者更有可能拥有较高的 CHLS-J 分数:结论:研究结果表明,CHLS-J 主要是一种经过验证的可靠量表,高健康水平组具有健康的饮食生活方式。本研究表明,CHLS-J 可用于测量 HL,并教育日本工人改变健康行为的必要性。
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引用次数: 0
[Health Idea from Altruistic Perspective]. [从利他角度看健康理念]。
Q3 Medicine Pub Date : 2024-01-01 DOI: 10.1265/jjh.24003
Takahiko Katoh

What is health? We all have a goal that we aspire for in our life-our "reason to live". Health is a pillar necessary for achieving our goal in life and I believe that altruism is the basic principle of this pillar. In this paper, I first discuss altruism in health from biological and economic perspectives, and then review the history of the concept of health. Next, I introduce the keywords necessary for understanding health and then present the points necessary for determining good health and for the role of each individual in issues concerning health. In conclusion, I would like to define health as a state of physical, mental and social well-being necessary for people to achieve self-achievement and happiness while living in society. Health is an attitude, and the very process of striving to achieve good health is itself "good health". In addition, altruism is fundamental to good health. The spirit of respect and empathy for not only humans health but also "planetary health" is important.

什么是健康?我们每个人都有自己的人生目标--"活着的理由"。健康是实现人生目标的必要支柱,我认为利他主义是这一支柱的基本原则。在本文中,我首先从生物学和经济学的角度讨论了健康中的利他主义,然后回顾了健康概念的历史。接下来,我介绍了理解健康所需的关键词,然后提出了确定健康状况和每个人在健康问题上的作用所需的要点。最后,我想把健康定义为人们在社会生活中实现自我成就和幸福所必需的身体、精神和社会福祉状态。健康是一种态度,努力实现健康的过程本身就是 "健康"。此外,利他主义也是健康的根本。不仅对人类健康,而且对 "地球健康 "的尊重和同情精神也很重要。
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引用次数: 0
[Ethics Review Committees of Public Health Institutes in Japan]. [日本公共卫生研究所伦理审查委员会]。
Q3 Medicine Pub Date : 2024-01-01 DOI: 10.1265/jjh.24002
Yusuke Inoue, Shinichi Sato, Izen Ri, Kyoko Mimura, Masahiro Kitao, Ayako Kamisato, Kaori Muto

Objectives: Recent legislative changes in the wake of the novel coronavirus pandemic have placed an increased emphasis on the research activities of Local Public Health Institutes (PHIs) in Japanese municipalities. However, few studies have examined the ethical review processes of these institutes.

Methods: We analyzed information on (a) the status and year of establishment of "Ethics Review Committees" (and equivalent committees), (b) the number of review cases for each year, (c) the status of public disclosure of committee activities, and (d) the composition of committee members for 85 PHIs across Japan. Publicly available information from each PHI and the Ministry of Health, Labour and Welfare was used for the analysis.

Results: Out of 85 PHIs nationwide, about half of them publicly disclosed the establishment of their committees (41 committees, 48.2%). The number of review cases handled by the committees varied, with some committees having no cases or only one case. Among the committees, approximately 20% still maintained adherence to outdated national research ethics guidelines, and approximately 15% did not specify any guidelines they followed. Furthermore, we identified committees without external members (at least two committees) and those lacking public representation (four committees).

Conclusion: There are differences in the operational performance of ethics review committees at PHIs, possibly owing to varying levels of understanding of the guidelines, the degree of proactive engagement in academic research, and the emphasis on human subject research. There is a crucial need to accumulate and share experiences that support the review functions of the committees.

目的:在新型冠状病毒大流行之后,最近的立法改革更加重视日本各市地方公共卫生研究所(PHIs)的研究活动。然而,很少有研究对这些机构的伦理审查程序进行研究:我们分析了日本全国 85 个公共卫生研究所的以下信息:(a) "伦理审查委员会"(及同等委员会)的成立情况和年份;(b) 每年的审查案例数量;(c) 委员会活动的公开情况;(d) 委员会成员的构成。分析采用了各 PHI 和厚生劳动省的公开信息:在全国 85 个 PHI 中,约有一半公开披露了其委员会的成立情况(41 个委员会,48.2%)。委员会处理的审查案件数量各不相同,有些委员会没有案件或只有一个案件。在这些委员会中,约有 20% 的委员会仍在遵守过时的国家研究伦理指导原则,约有 15% 的委员会没有明确说明他们所遵循的任何指导原则。此外,我们还发现了没有外部成员的委员会(至少两个)和没有公众代表的委员会(四个):PHI 的伦理审查委员会在运作绩效方面存在差异,这可能是由于对指导方针的理解程度、主动参与学术研究的程度以及对人体研究的重视程度不同造成的。亟需积累和分享支持委员会审查职能的经验。
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引用次数: 0
[Development of a Risk Prediction Model and a Simple Assessment Sheet for Screening Undernutrition Using Factors Related to Food Environment Accessibility among Older Adults Living Alone in Semi-mountainous Areas]. [利用食物环境可及性相关因素筛选半山区独居老年人营养不良风险预测模型和简易评估表的建立]。
Q3 Medicine Pub Date : 2024-01-01 DOI: 10.1265/jjh.24008
Ai Nakai, Ikuharu Morioka

Objectives: In addition to an aging population, the number of single-person households is increasing in semi-mountainous areas. The nutritional status of older adults living alone has also been studied as they are prone to undernutrition. In this study, we aimed to develop a risk prediction model and a simple assessment sheet for screening undernutrition using factors related to food environment accessibility among older adults living alone in semi-mountainous areas.

Methods: This study included 181 participants (36 men, 145 women) living alone in four semi-mountainous areas (mean age, 83.6 years). Factors related to accessibility to the food environment were measured using 30 predefined items. The Mini-Nutritional Assessment Short Form was used for the nutritional status assessment.

Results: An exploratory factor analysis was performed using 30 items of the food environment accessibility, among which, 16 items were extracted. On the basis of the results of a logistic regression analysis using 17 items including age, 10 items were selected to be included in the logistic model to predict the risk of undernutrition. The risk prediction model showed fair discrimination (area under the curve=0.722) and calibration capabilities (Hosme-Lemeshow test, p=0.822). A simple rating sheet was developed using a model to predict undernutrition risk using factors related to food environment accessibility among older adults living alone in semi-mountainous areas.

Conclusions: A simple assessment sheet was developed to evaluate the undernutrition risk using factors related to food environment accessibility among older adults living alone in semi-mountainous areas.

目标:除了人口老龄化外,半山区的单身家庭数量也在增加。独居老年人的营养状况也进行了研究,因为他们容易营养不良。在这项研究中,我们的目的是建立一个风险预测模型和一个简单的评估表,用于筛选与食物环境可及性相关的半山区独居老年人的营养不良。方法:本研究纳入4个半山区独居者181人(男36人,女145人),平均年龄83.6岁。与食品环境可及性相关的因素使用30个预定义项目进行测量。营养状况评估采用迷你营养评估简表。结果:利用食品环境可达性的30个项目进行探索性因子分析,提取出16个项目。在对年龄等17个项目进行logistic回归分析的基础上,选择10个项目纳入logistic模型预测营养不良风险。风险预测模型具有良好的判别性(曲线下面积=0.722)和校准能力(homme - lemeshow检验,p=0.822)。利用与半山区独居老年人的食物环境可及性相关因素的模型,编制了一份简单的评分表,以预测营养不良风险。结论:开发了一个简单的评估表,利用与食物环境可及性相关的因素来评估半山区独居老年人的营养不良风险。
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引用次数: 0
Intact moral decision-making in adults with moderate-severe traumatic brain injury. 中重度脑外伤成人的完整道德决策。
Q3 Medicine Pub Date : 2023-12-01 Epub Date: 2022-05-03 DOI: 10.1017/BrImp.2022.11
Malcolm Edwards, Emily L Morrow, Melissa C Duff

Background and aim: Deficits in decision-making are a common consequence of moderate-severe traumatic brain injury (TBI). Less is known, however, about how individuals with TBI perform on moral decision-making tasks. To address this gap in the literature, the current study probed moral decision-making in a sample of individuals with TBI using a widely employed experimental measure.

Methods/hypothesis: We administered a set of 50 trolley-type dilemmas to 31 individuals with TBI and 31 demographically matched, neurotypical comparison participants. We hypothesized that individuals with TBI would be more likely to offer utilitarian responses to personal dilemmas than neurotypical peers.

Results: In contrast to our hypothesis, we observed that individuals with TBI were not more likely to offer utilitarian responses for personal dilemmas.

Conclusion: Our results suggest that moral decision-making ability is not uniformly impaired following TBI. Rather, neuroanatomical (lesion location) and demographic (age at injury) characteristics may be more predictive of a disruption in moral decision-making than TBI diagnosis or injury severity alone. These results inform the neurobiology of moral decision-making and have implications for characterizing patterns of spared and impaired cognitive abilities in TBI.

背景和目的:决策缺陷是中重度创伤性脑损伤(TBI)的常见后果。然而,人们对创伤性脑损伤患者在道德决策任务中的表现知之甚少。为了填补这一文献空白,本研究使用一种广泛使用的实验测量方法,对创伤性脑损伤患者样本的道德决策能力进行了探究:我们对 31 名创伤性脑损伤患者和 31 名人口统计学匹配的神经畸形对比参与者进行了一组 50 个电车式困境测试。我们假设,与神经正常的同伴相比,患有创伤性脑损伤的患者更有可能对个人困境做出功利性反应:结果:与我们的假设相反,我们发现患有创伤性脑损伤的人并没有更有可能对个人困境做出功利性反应:结论:我们的研究结果表明,创伤性脑损伤患者的道德决策能力并不是一致受损的。相反,神经解剖学(病变位置)和人口统计学(受伤时的年龄)特征可能比单纯的创伤性脑损伤诊断或受伤严重程度更能预测道德决策的障碍。这些结果为道德决策的神经生物学提供了信息,并对描述创伤性脑损伤后认知能力幸免和受损的模式具有意义。
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引用次数: 0
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Japanese Journal of Hygiene
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