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Acute mesenteric thrombosis in a pregnant woman with Factor V Leiden mutation with a history of in vitro fertilization and embryo transfer: case report and literature review 有体外受精和胚胎移植史的Leiden因子V突变孕妇急性肠系膜血栓形成一例报告并文献复习
Q3 Medicine Pub Date : 2022-12-30 DOI: 10.18597/rcog.3854
Furkan Karahan, Arif Atay, Fatma Hüsniye Dilek, Cengiz Tavusbay, Murat Kemal Atahan

Objectives: To report the case of a patient diagnosed with acute mesenteric vein thrombosis (AMVT) associated with Factor V Leiden mutation and a history of in vitro fertilization and embryo transfer and review the literature on risk factors and treatments performed for AMVT.

Materials and methods: We reported the case of a 37-year-old pregnant woman. A bibliographic search was carried out in Medline/PubMed and LILACS, filtering by type of language (English and Spanish). Primary cohort studies, cases and controls, case reports and case series were included, which addressed the risk factors associated with the development of acute mesenteric thrombosis during pregnancy and treatments performed.

Results: The search identified cases and control studies, case reports and case series related to mesenteric ischemia, pregnancy and in vitro fertilization. The literature reported that the main factors associated with mesenteric ischemia are pregnancy itself, genetic factors, drugs, protein C and protein S deficiency and idiopathic causes.

Conclusions: SMV thrombosis is a life-threatening and very rarely seen condition that emerges in pregnancies. The literature suggests that, during gestation, the factors associated with the development of acute mesenteric thrombosis are hypercoagulability induced by pregnancy, the administration of oral estrogen during IVF-ET, and other precipitating factors. More studies are required to better understand the possible additional factors and build better optimal treatment algorithms.

目的:报告1例诊断为急性肠系膜静脉血栓形成(AMVT)并伴有因子V Leiden突变及体外受精和胚胎移植史的患者,并对AMVT的危险因素及治疗进行文献回顾。材料与方法:我们报告了一例37岁的孕妇。在Medline/PubMed和LILACS中进行书目检索,按语言类型(英语和西班牙语)进行筛选。包括主要队列研究、病例和对照、病例报告和病例系列,这些研究涉及与妊娠期间急性肠系膜血栓形成相关的危险因素和治疗方法。结果:检索确定了与肠系膜缺血、妊娠和体外受精相关的病例和对照研究、病例报告和病例系列。文献报道与肠系膜缺血相关的主要因素有妊娠本身、遗传因素、药物、蛋白C和蛋白S缺乏以及特发性原因。结论:SMV血栓形成是一种危及生命的非常罕见的情况出现在怀孕。文献提示,在妊娠期,与急性肠系膜血栓形成相关的因素有妊娠引起的高凝、IVF-ET期间口服雌激素以及其他诱发因素。需要更多的研究来更好地了解可能的其他因素,并建立更好的最佳治疗算法。
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引用次数: 1
Uterine necrosis following hemostatic compression suture: case report and review of the literature 止血加压缝合后子宫坏死:1例报告及文献复习
Q3 Medicine Pub Date : 2022-12-30 DOI: 10.18597/rcog.3856
Raquel García-Guerra, Myrna Assaf-Balut, Sara El-Bakkali, Irene Pérez de Ávila-Benavides, Miguel Ángel Huertas-Fernández

Objectives: To present a case of uterine necrosis following hemostatic suturing to control postpartum bleeding, and to review the literature in order to identify the suture techniques employed, clinical findings, diagnostics and treatment in the clinical cases described.

Material and methods: A 34-year-old woman presenting with abdominal pain eight days after cesarean delivery due to placenta previa who required B-Lynch compression suture due to uterine atony, and who was diagnosed with uterine necrosis. The patient underwent total abdominal hysterectomy with a satisfactory recovery. A systematic literature search was conducted in the Medline vía Pubmed, Embase and Web of Science databases. The search included case series and reports, and cohorts of women with uterine necrosis following the use of uterine compression sutures for postpartum bleeding. The analysis included sociodemographic and clinical variables at the time of diagnosis, suturing technique, diagnostic tests and treatment.

Results: Overall, 23 studies with 24 patients were included. Of all necrosis cases, 83% occurred following cesarean section. B-Lynch was the suturing technique most frequently used (66 %), followed by the Cho suture (25 %). The most frequent symptoms were fever and abdominal pain. The most commonly used diagnostic test was computed tomography (9/24 cases). Hysterectomy was performed in the majority of cases (75 %).

Conclusions: Although rare, uterine wall necrosis is a serious complication. It would be advisable to design follow-up cohort studies of women undergoing these procedures in order to determine the incidence of associated complications.

目的:报告1例止血缝合后子宫坏死控制产后出血的病例,并复习文献,以确定临床病例所采用的缝合技术,临床表现,诊断和治疗。材料与方法:34岁女性,因前置胎盘剖宫产后8天出现腹痛,因子宫张力不全需B-Lynch压迫缝合,诊断为子宫坏死。患者行全腹子宫切除术,恢复良好。在Medline vía Pubmed、Embase和Web of Science数据库中进行了系统的文献检索。搜索包括病例系列和报告,以及使用子宫压迫缝合线治疗产后出血后子宫坏死的妇女队列。分析包括诊断时的社会人口学和临床变量、缝合技术、诊断测试和治疗。结果:总共纳入23项研究,24例患者。在所有坏死病例中,83%发生在剖宫产术后。B-Lynch是最常用的缝合技术(66%),其次是Cho缝合(25%)。最常见的症状是发烧和腹痛。最常用的诊断检查是计算机断层扫描(9/24)。大多数病例(75%)行子宫切除术。结论:子宫壁坏死虽罕见,但却是一种严重的并发症。为确定相关并发症的发生率,建议对接受这些手术的妇女进行随访队列研究。
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引用次数: 2
Successful vaginal delivery and maternal and perinatal outcomes in patients with a history of cesarean section and labor trial: cross-sectional study 有剖宫产史和产程试验的患者阴道分娩成功和产妇及围产儿结局:横断面研究
Q3 Medicine Pub Date : 2022-12-30 DOI: 10.18597/rcog.3874
Carolina Arango-Montoya, María Ximena López-Arroyave, Juliana Marín-Ríos, Alejandro Colonia-Toro, José Bareño-Silva

Objectives: To determine the proportion of successful vaginal deliveries in women with prior cesarean section; to describe maternal and perinatal complications; and to examine the factors associated with vaginal delivery.

Materials and methods: Descriptive cross-sectional study of women with a history of cesarean delivery, gestational age of more than 24 weeks, singleton live fetuses, with prior vaginal delivery who received care in a high complexity public institution in 2019. Patients with a history of more than one cesarean section or myomectomy were excluded. Consecutive sampling was used. Sociodemographic and obstetric variables, delivery route and maternal and perinatal complications were measured. A descriptive analysis as well as a multivariate exploratory analysis of the factors associated with successful vaginal delivery were carried out.

Results: Among 286 pregnant women included, the percentage of successful vaginal deliveries was 74.5 %. Maternal complications were identified in 3.2 % of vaginal delivery cases and in 6.8 % of cesarean births. Complications occurred in 1.3 % of all live neonates; there were 2 perinatal deaths. An association was found between successful vaginal delivery and a history of prior vaginal delivery (OR: 2.7; 95 % CI: 1.15-6.29); a Bishop score greater than 6 (OR: 2.2; 95 % CI: 1.03-4.56); spontaneous labor initiation (OR: 4.5; IC 95 % CI: 2.07-9.6); and maternal age under 30 years (OR:2.28; 95 % CI: 1.2-4.2).

Conclusions: Vaginal delivery is a safe option to consider in patients with prior cesarean section, in particular in cases of spontaneous labor initiation or prior vaginal delivery. Prospective cohorts are needed in order to confirm these findings.

目的:了解有剖宫产史的妇女阴道分娩成功率;描述产妇和围产期并发症;并检查与阴道分娩有关的因素。材料与方法:对2019年在某高复杂性公共机构接受治疗的剖宫产史、胎龄大于24周、单胎活胎、阴道分娩史的女性进行描述性横断面研究。排除有一次以上剖宫产史或子宫肌瘤切除术史的患者。采用连续抽样。测量了社会人口统计学和产科变量、分娩路线以及产妇和围产期并发症。对成功阴道分娩相关因素进行了描述性分析和多变量探索性分析。结果:286例孕妇阴道分娩成功率为74.5%。在3.2%的阴道分娩病例和6.8%的剖宫产病例中发现了产妇并发症。1.3%的活产新生儿出现并发症;有2例围产期死亡。成功阴道分娩与既往阴道分娩史之间存在关联(OR: 2.7;95% ci: 1.15-6.29);主教得分大于6 (OR: 2.2;95% ci: 1.03-4.56);自然分娩开始(OR: 4.5;IC 95% ci: 2.07-9.6);母亲年龄在30岁以下(OR:2.28;95% ci: 1.2-4.2)。结论:对于有剖宫产史的患者,阴道分娩是一种安全的选择,特别是在自然分娩或阴道分娩的情况下。需要前瞻性队列来证实这些发现。
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引用次数: 0
Reflections on the performance of the Colombian Minister of Health regarding the management of the COVID-19 pandemic, sexual and reproductive health and public health 对哥伦比亚卫生部长在管理COVID-19大流行、性健康和生殖健康以及公共卫生方面表现的思考
Q3 Medicine Pub Date : 2022-12-01 DOI: 10.18597/rcog.3938
Jorge Enrique Tolosa-Ardila

Objectives: To offer a critical assessment of the incumbent Health Minister’s performance at the end of the Ivan Duque administration regarding the management of the pandemic, sexual and reproductive health, and public health in Colombia.

Material and methods: Based on the description of challenges faced during this time period, we present evidence regarding performance results which, together with the author’s opinion, offer an assessment of the work done.

Conclusions: The Health Minister’s performance in managing the pandemic fell short, in particular as concerns sexual and reproductive health, as well as public health.

目标:对现任卫生部长在伊万·杜克政府结束时在哥伦比亚管理大流行病、性健康和生殖健康以及公共卫生方面的表现进行批判性评估。材料和方法:基于对这一时期所面临的挑战的描述,我们提出了有关绩效结果的证据,连同作者的观点,对所做的工作进行了评估。结论:卫生部长在管理大流行病方面的表现不佳,特别是在性健康和生殖健康以及公共卫生方面。
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引用次数: 0
Design of biomedical devices and business plans. The new alternatives for the degree work of our resident doctors 设计生物医学设备和商业计划。我国住院医师学位工作的新选择
Q3 Medicine Pub Date : 2022-09-30 DOI: 10.18597/rcog.3926
Alejandro Vargas-Gutiérrez, José Ricardo Navarro-Vargas
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引用次数: 0
Colombian Consensus on the Treatment of Placenta Accreta Spectrum (PAS) 哥伦比亚胎盘早剥治疗共识(PAS)
Q3 Medicine Pub Date : 2022-09-30 DOI: 10.18597/rcog.3877
Albaro José Nieto-Calvache, José Enrique Sanín-Blair, Haidi Marcela Buitrago-Leal, Jesús Andrés Benavides-Serralde, Juliana Maya-Castro, Adda Piedad Rozo-Rangel, Adriana Messa-Bryon, Alejandro Colonia-Toro, Armando Rafael Gómez-Castro, Arturo Cardona-Ospina, Carlos Eduardo Caicedo-Cáceres, Elkin Fabian Dorado-Roncancio, Jaime Luis Silva, Javier Andrés Carvajal-Valencia, Jesús Arnulfo Velásquez-Penagos, Jorge Ernesto Niño-González, Juan Manuel Burgos-Luna, Juan Carlos Rincón-García, Lía Matera-Torres, Orlando Afranio Villamizar-Galvis, Sandra Ximena Olaya-Garay, Virna Patricia Medina-Palmezano, Jimmy Castañeda
<p><strong>Introduction: </strong>Placenta accreta spectrum (PAS) is a condition associated with massive postpartum bleeding and maternal mortality. Management guidelines published in high income countries recommend the participation of interdisciplinary teams in hospitals with sufficient resources for performing complex procedures. However, some of the recommendations contained in those guidelines are difficult to implement in low and medium income countries.</p><p><strong>Objectives: </strong>The aim of this consensus is to draft general recommendations for the treatment of PAS in Colombia.</p><p><strong>Materials and methods: </strong>Twenty-three panelists took part in the consensus with their answers to 31 questions related to the treatment of PAS. The panelists were selected based on participation in two surveys designed to determine the resolution capabilities of national and regional hospitals. The modified Delphi methodology was used, introducing two successive discussion rounds. The opinions of the participants, with a consensus of more than 80%, as well as implementation barriers and facilitators, were taken into consideration in order to issue the recommendations.</p><p><strong>Results: </strong>The consensus draftedfive recommendations, integrating the answers of the panelists. Recommendation 1. Primary care institutions must undertake active search of PAS in patients with risk factors: placenta praevia and history of myomectomy or previous cesarean section. In case of ultrasound signs suggesting PAS, patients must be immediately referred, without a minimum gestational age, to hospitals recognized as referral centers. Online communication and care modalities may facilitate the interaction between primary care institutions and referral centers for PAS. The risks and benefits of telemedicine modalities must be weighed.Recommendation 2. Referral hospitals for PAS need to be defined in each region of Colombia, ensuring coverage throughout the national territory. It is advisable to concentrate the flow of patients affected by this condition in a few hospitals with surgical teams specifically trained in PAS, availability of specialized resources, and institutional efforts at improving quality of care with the aim of achieving better health outcomes in pregnant women with this condition. To achieve this goal, participants recommend that healthcare regulatory agencies at a national and regional level should oversee the process of referral for these patients, expediting administrative pathways in those cases in which there is no prior agreement between the insurer and the selected hospital or clinic.Recommendation 3. Referral centers for patients with PAS are urged to build teams consisting of a fixed group of specialists (obstetricians, urologists, general surgeons, interventional radiologists) entrusted with the care of all PAS cases. It is advisable for these interdisciplinary teams to use the “intervention bundle” model as a guidance f
在缺乏产前诊断的情况下,也就是说,在术中发现 PAS(子宫前部紫色隆起或新生血管的证据),以及未经培训的人员参与的情况下,可以考虑三种方案:方案 1:在没有立即分娩或阴道分娩指征的情况下,建议推迟剖宫产(在切开子宫前关闭腹腔),直到获得安全手术的建议资源。方案 2:如果有立即分娩的指征(例如方案 3:如果阴道出血导致无法进行明确的 PAS 处理,则必须通过宫底娩出胎儿,然后进行子宫修补并重新评估情况。有时,胎儿娩出会减少胎盘血流,阴道出血也会减少或消失,从而有可能推迟 PAS 的最终处理。如果持续大量出血,应利用所有可用资源进行子宫切除术:人工主动脉压迫、立即呼叫受过最佳培训的外科医生、其他医院专家团队的远程医疗支持。如果患者存在 PAS 的风险因素(如子宫肌瘤切除术或曾进行剖宫产),且在阴道分娩后出现胎盘滞留,则建议在进行人工胎盘剥离之前先确认诊断的可能性(如通过超声波检查):我们希望哥伦比亚就胎盘早剥问题达成的首个共识能成为更多讨论和合作的基础,从而改善受此问题影响的妇女的临床治疗效果。为了评估这些建议的适用性和有效性,还需要进行更多的研究。
{"title":"Colombian Consensus on the Treatment of Placenta Accreta Spectrum (PAS)","authors":"Albaro José Nieto-Calvache, José Enrique Sanín-Blair, Haidi Marcela Buitrago-Leal, Jesús Andrés Benavides-Serralde, Juliana Maya-Castro, Adda Piedad Rozo-Rangel, Adriana Messa-Bryon, Alejandro Colonia-Toro, Armando Rafael Gómez-Castro, Arturo Cardona-Ospina, Carlos Eduardo Caicedo-Cáceres, Elkin Fabian Dorado-Roncancio, Jaime Luis Silva, Javier Andrés Carvajal-Valencia, Jesús Arnulfo Velásquez-Penagos, Jorge Ernesto Niño-González, Juan Manuel Burgos-Luna, Juan Carlos Rincón-García, Lía Matera-Torres, Orlando Afranio Villamizar-Galvis, Sandra Ximena Olaya-Garay, Virna Patricia Medina-Palmezano, Jimmy Castañeda","doi":"10.18597/rcog.3877","DOIUrl":"10.18597/rcog.3877","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Placenta accreta spectrum (PAS) is a condition associated with massive postpartum bleeding and maternal mortality. Management guidelines published in high income countries recommend the participation of interdisciplinary teams in hospitals with sufficient resources for performing complex procedures. However, some of the recommendations contained in those guidelines are difficult to implement in low and medium income countries.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objectives: &lt;/strong&gt;The aim of this consensus is to draft general recommendations for the treatment of PAS in Colombia.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Materials and methods: &lt;/strong&gt;Twenty-three panelists took part in the consensus with their answers to 31 questions related to the treatment of PAS. The panelists were selected based on participation in two surveys designed to determine the resolution capabilities of national and regional hospitals. The modified Delphi methodology was used, introducing two successive discussion rounds. The opinions of the participants, with a consensus of more than 80%, as well as implementation barriers and facilitators, were taken into consideration in order to issue the recommendations.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The consensus draftedfive recommendations, integrating the answers of the panelists. \u0000Recommendation 1. Primary care institutions must undertake active search of PAS in patients with risk factors: placenta praevia and history of myomectomy or previous cesarean section. In case of ultrasound signs suggesting PAS, patients must be immediately referred, without a minimum gestational age, to hospitals recognized as referral centers. Online communication and care modalities may facilitate the interaction between primary care institutions and referral centers for PAS. The risks and benefits of telemedicine modalities must be weighed.\u0000Recommendation 2. Referral hospitals for PAS need to be defined in each region of Colombia, ensuring coverage throughout the national territory. It is advisable to concentrate the flow of patients affected by this condition in a few hospitals with surgical teams specifically trained in PAS, availability of specialized resources, and institutional efforts at improving quality of care with the aim of achieving better health outcomes in pregnant women with this condition. To achieve this goal, participants recommend that healthcare regulatory agencies at a national and regional level should oversee the process of referral for these patients, expediting administrative pathways in those cases in which there is no prior agreement between the insurer and the selected hospital or clinic.\u0000Recommendation 3. Referral centers for patients with PAS are urged to build teams consisting of a fixed group of specialists (obstetricians, urologists, general surgeons, interventional radiologists) entrusted with the care of all PAS cases. It is advisable for these interdisciplinary teams to use the “intervention bundle” model as a guidance f","PeriodicalId":35675,"journal":{"name":"Revista Colombiana de Obstetricia y Ginecologia","volume":"73 3","pages":"283-316"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/12/e6/2463-0225-rcog-73-03-3877.PMC9674383.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10404524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ovarian sex cord tumor with annular tubules: case report and review of the literature 卵巢性索肿瘤伴环状小管:1例报告及文献复习
Q3 Medicine Pub Date : 2022-09-30 DOI: 10.18597/rcog.3888
Franco Rafael Ruiz-Echeverría, María Islena Beltrán-Salazar, Pedro Hernando Calderón-Quiroz, Juan David Lalinde-Triviño, Maribel Palencia-Palacios, Oscar Suescún-Garay

Objectives: To report a case of ovarian sex cord tumor with annular tubules (SCTAT) and conduct a literature review on diagnosis, treatment and prognosis of this condition.

Material and methods: Case report of a woman with a final diagnosis of advanced SCTAT seen at the National Cancer Institute in Bogota (Colombia) who received surgical treatment and chemotherapy with a satisfactory course after 6 months. A literature search was conducted in the Medline via PubMed, LILACS and Scielo databases, including case reports and series of women diagnosed with SCTAT published since 1990, not using age ranges. Information about diagnosis, treatment and reported prognosis was retrieved. A narrative summary of the findings was prepared.

Results: Fourteen publications with 26 patients were included. Mean age at diagnosis was 22.5 years. The main symptoms were menstruation abnormalities and pelvic pain. Computed tomography (CT) was the imaging technology most frequently used. Surgical treatment was used in all cases, together with chemotherapy in 29 %; 2 patients received radiotherapy. Recurrence occurred in 20 % of cases. Mortality was 12.5 %, with all deaths occurring within the first year.

Conclusions: There is a paucity of information about the diagnostic utility of imaging, tumor markers and histochemical studies, as well as prognosis of this disease condition. Surgery is the treatment of choice, taking into consideration the patient’s wishes regarding fertility, as well as the stage of the tumor. Further studies are needed to provide more detailed information about this condition.

目的:报告1例卵巢性索肿瘤伴环状小管(SCTAT),并对该病的诊断、治疗及预后进行文献复习。材料和方法:病例报告:在波哥大(哥伦比亚)国家癌症研究所最终诊断为晚期SCTAT的妇女,在6个月后接受手术治疗和化疗,疗程满意。通过PubMed、LILACS和Scielo数据库在Medline进行文献检索,包括自1990年以来发表的病例报告和诊断为SCTAT的妇女系列,未使用年龄范围。检索有关诊断、治疗和报告预后的信息。编写了调查结果的叙述性摘要。结果:纳入14篇文献,26例患者。诊断时的平均年龄为22.5岁。主要症状为月经异常和盆腔疼痛。计算机断层扫描(CT)是最常用的成像技术。所有病例均采用手术治疗,29%合并化疗;2例患者接受放疗。复发率为20%。死亡率为12.5%,所有死亡都发生在第一年。结论:关于影像学、肿瘤标志物和组织化学研究的诊断价值以及该疾病的预后信息缺乏。考虑到患者对生育能力的意愿以及肿瘤的阶段,手术是治疗的选择。需要进一步的研究来提供关于这种情况的更详细的信息。
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引用次数: 0
The State and the obligation to guarantee maternal and perinatal health 国家和保障产妇和围产期健康的义务
Q3 Medicine Pub Date : 2022-09-30 DOI: 10.18597/rcog.3957
Hernando Gaitán-Duarte
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引用次数: 0
Adherence to recommendations for preventing early neonatal sepsis associated with Streptococcus agalactiae colonization in a referral center in Bogotá, Colombia, 2019 2019年,哥伦比亚波哥大<e:1>一家转诊中心遵守预防与无乳链球菌定植相关的早期新生儿败血症的建议
Q3 Medicine Pub Date : 2022-09-30 DOI: 10.18597/rcog.3917
Ana María Ospino-Muñoz, Edna Alejandra Bonza-González, Cristian David Arévalo-Mojica, Jorge Andrés Rubio-Romero

Objectives: To assess adherence to screening recommendations for the prevention of neonatal sepsis, and describe the prevalence of colonization by Group B streptococcus (GBS) as well as the perinatal outcomes associated with colonization by this bacterium.

Material and methods: Retrospective cohort study that included pregnant women at term and their newborns, seen at a private high-complexity clinic in Bogota, between July 1 and December 31, 2019. Adherence to screening and intrapartum antibiotic prophylaxis in pregnant women colonized with group B streptococcus, as well as the prevalence of colonization and early adverse perinatal outcomes were assessed.

Results: Overall, 1928 women were included. Adherence to screening was 68.0 % (95 % CI: 66-70.1) and 87.9 % to intrapartum antibiotic administration (95 % CI: 87.8-88); non-indicated use of antibiotics occurred in 14.7 % of the women, for 86.3 % final adherence to antibiotic prophylaxis. The prevalence of GBS colonization was 12.5 % (95 % CI: 10.7-14.3); the incidence of neonatal hospitalization was 27.5 % (95 % CI: 16.3-33.7). There were no cases of mortality or early neonatal sepsis attributable to screening status, colonization or prophylactic antibiotics for GBS.

Conclusions: Additional studies in other centers are required in order to determine adherence to this guideline, particularly in those that receive users affiliated to the subsidized regime which covers the most vulnerable population. Also, new population studies of GBS prevalence and cost-effectiveness of universal screening compared to risk factor-based antibiotic prophylaxis are needed.

目的:评估新生儿脓毒症预防筛查建议的依从性,描述B群链球菌(GBS)定植的患病率以及与该细菌定植相关的围产期结局。材料和方法:回顾性队列研究,包括2019年7月1日至12月31日在波哥大一家私人高复杂性诊所就诊的足月孕妇及其新生儿。评估了感染B群链球菌的孕妇对筛查和产时抗生素预防的依从性,以及定植的患病率和早期不良围产期结局。结果:共纳入1928名女性。筛查依从率为68.0% (95% CI: 66-70.1),产时给药依从率为87.9% (95% CI: 87.8-88);14.7%的妇女无指征使用抗生素,86.3%的妇女最终坚持使用抗生素预防。GBS定植率为12.5% (95% CI: 10.7-14.3);新生儿住院率为27.5% (95% CI: 16.3-33.7)。没有病例死亡或早期新生儿败血症可归因于筛查状态,定植或预防性抗生素的GBS。结论:需要在其他中心进行进一步的研究,以确定本指南的遵守情况,特别是在那些接受补贴制度附属用户的中心,该制度涵盖了最脆弱的人群。此外,需要对GBS患病率和普遍筛查与基于风险因素的抗生素预防相比的成本效益进行新的人群研究。
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引用次数: 0
Agreement between two scales used for assessing risk classification for thromboembolic events and the requirement of postpartum pharmacological prophylaxis 用于评估血栓栓塞事件风险分类和产后药物预防要求的两种量表之间的一致性
Q3 Medicine Pub Date : 2022-09-30 DOI: 10.18597/rcog.3831
Jaime Luis Silva-Herrera, Diana Patricia Polanía-Reyes, Adriana Carolina Aya-Porto, Angélica María Russi-Santamaría, Natalia Suarez-Pareja

Objectives: To determine agreement in assessing the need for postpartum pharmacological prophylaxis between the scale of the Royal College of Obstetricians and Gynaecologists and the Colombian guideline scale in a Level IV institution in Bogota, Colombia.

Material and methods: Diagnostic agreement study assembled on a cross-sectional study. The included population consisted of pregnant women with 24 or more weeks of pregnancy admitted between March 1 and April 30 of 2021 to a high complexity private institution in Bogotá, Colombia, for labor induction, in active labor, for elective cesarean section, or who required urgent cesarean section. Convenience sampling was used. Measured variables included demographics, risk factors, risk classification and pharmacological prophylaxis according to the two scales. The prevalence of risk factors for each scale was estimated and agreement regarding prophylaxis indication between the two scales was measured using the weighted kappa value.

Results: Overall, 320 patients were included. According to the scale of the Royal College Obstetricians and Gynaecologists, 54.7 % patients were classified as low risk, 42.5 % as intermediate risk and 2.8 % as high risk. The Colombian scale classified 80 % of patients as low risk, 17.2 % as intermediate risk, 2.2 % as high risk, and 0.6 % as very high risk. The weighted kappa value for agreement regarding the indication was 0.47 (95 % CI: 0.38-0.56).

Conclusions: Agreement between the two scales to determine the need for postpartum pharmacological prophylaxis is moderate. Risk classification criteria for the Colombian scale should be validated in a second cohort. Moreover, the predictive ability of the Colombian guideline tool should be assessed at different cut-off points in terms of the consequences of false positive and false negative results.

目的:确定在评估产后药物预防需求方面,哥伦比亚波哥大一家四级机构的皇家妇产科学院量表和哥伦比亚指导量表的一致性。材料和方法:诊断一致性研究集中在一个横断面研究。纳入的人群包括在2021年3月1日至4月30日期间在哥伦比亚波哥大一家高度复杂的私人机构接受引产、主动分娩、选择性剖宫产或需要紧急剖宫产的怀孕24周或更长时间的孕妇。采用方便抽样。测量变量包括人口统计学、危险因素、危险分类和药物预防。评估每个量表中危险因素的患病率,并使用加权kappa值测量两个量表之间关于预防指征的一致性。结果:共纳入320例患者。根据皇家学院妇产科医生的量表,54.7%的患者被分类为低风险,42.5%为中等风险,2.8%为高风险。哥伦比亚量表将80%的患者分类为低风险,17.2%为中等风险,2.2%为高风险,0.6%为非常高风险。关于适应症的一致性加权kappa值为0.47 (95% CI: 0.38-0.56)。结论:两个量表在确定是否需要产后药物预防方面的一致性是中等的。哥伦比亚量表的风险分类标准应在第二个队列中进行验证。此外,哥伦比亚指南工具的预测能力应根据假阳性和假阴性结果的后果在不同的截止点进行评估。
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Revista Colombiana de Obstetricia y Ginecologia
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