Progresos en Obstetricia y Ginecologia最新文献

Objective

To compare serum troponin i concentrations in eclamptic patients, preeclamptic patients, and normotensive pregnant women.

Materials and method

We included 30 patients with mild preeclampsia (group A), 30 patients with severe preeclampsia (group B), and 30 patients with eclampsia (group C). A control group was selected with a similar age and body mass index to the study groups and consisted of 30 healthy normotensive pregnant women (group D). Only nulliparous women were included. Serum samples were collected from all patients before delivery and in the study groups immediately after diagnosis for troponin i determination.

Results

Serum troponin i values were higher in eclamptic patients (0.171 ± 0.025 ng/mL) and in severe preeclamptic patients (0.168 ± 0.024 ng/mL) and were lower in mild preeclamptic patients (0.123 ± 0.015 ng/mL). Serum troponin i values were significantly higher in the study groups than in the control group (0.049 ± 0.034 ng/mL; P < .0001). Linear regression analysis revealed that the factors significantly related to serum troponin i concentrations were 24-hour proteinuria and creatinine (P < .05).

Conclusion

Tropinin i concentrations were higher in eclamptic and preeclamptic patients than in healthy normotensive pregnant women without these complications.

Cervical cancer is a very common disease with a high mortality rate worldwide, despite multiple types of treatment. We report the case of a 47-year-old woman with metastatic cervical cancer at the time of diagnosis (FIGO stage IVB) who was treated with carboplatin-based chemotherapy and surgery. The patient had a complete response to the treatment and currently has a disease-free survival of 53 months.

Fibroadenoma is the most common benign breast tumor in women aged between 20 and 35 years. There are different variants, including giant fibroadenoma. We report a case of this entity. Giant fibroadenoma has been defined as a fibroadenoma with a maximum diameter larger than 5 cm or weighing more than 500 g. The initial diagnosis is based on clinical history and physical examination and definitive diagnosis is made by histological analysis. Surgical treatment should be individually assessed and resection is recommended in patients with fibroadenomas with very rapid growth and in highly symptomatic patients. In patients with severe mammary asymmetry, the inverted «T» technique can be used, which is effective in reducing the volume and correcting ptosis in breast hypertrophy. Mastectomy is also an option.

Cervical cancer is one of the most common malignancies diagnosed during pregnancy. The management of these patients is individualized and is based on gestational age at diagnosis, tumor stage, and the patient's desire to continue the pregnancy or not. We report a case of adenocarcinoma of the cervix that was diagnosed in the 18th week of pregnancy, in which the approach adopted was expectant management.

Objectives

To review and update the different treatment options of pharmacological abortion.

Material and methods

Literature search and review.

Results

The most widely used treatment in pregnancies of less than 9 weeks (63 days) is a combination of 200 mg of mifepristone followed by 800 micrograms of misoprostol at 24-48 hours administered either vaginally or orally. Efficacy rates vary from 96.12% to 97.43% and the incidence of severe effects is low (0.2%).

Conclusions

Medical abortion is safe and effective and should be offered to all women requesting a termination up to 63 days of gestation.