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Enlarging the surgeon's mind in aortic stenosis. 扩大外科医生对主动脉瓣狭窄的认识。
IF 0.7 Q3 Medicine Pub Date : 2024-11-08 DOI: 10.1177/02184923241296165
Arkalgud Sampath Kumar
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引用次数: 0
Total arterial revascularization with RIMA-LIMA-Y configuration in patients with left subclavian artery stenosis. 在左锁骨下动脉狭窄患者中使用 RIMA-LIMA-Y 配置进行全动脉再血管化。
IF 0.7 Q3 Medicine Pub Date : 2024-11-03 DOI: 10.1177/02184923241284318
Anit Kumar, Bharath Sundar, Swanand Khapli, Sayyed Azhar Salim Ahmed, Dhiraj Barman, Lalit Kapoor, Unmesh Chakraborty

Background: Subclavian artery stenosis (SAS) occurs in 6% of patients undergoing coronary artery bypass grafting (CABG). Complications such as subclavian-coronary steal are common. Revascularization options in such cases remain debatable.

Methods: In this case series, all patients with angina, had severe triple vessel disease on angiography. All tests including computed tomography (CT) angiography of neck vessels, were done as part of routine workup for CABG.

Results: The patients, all males, had a mean age of 66.5 years with three of them having hypertension and diabetes. All were ex-smokers with mean ejection fraction (EF) of 60.1%. CT angiography of neck vessels revealed that two patients had moderate to severe while one had severe left SAS and another had severe proximal left internal mammary artery (LIMA) stenosis. Total arterial revascularization was performed, with an average of 3.5 distal grafts. The LIMA graft was employed in a Y graft configuration, anastomosed to in-situ right internal mammary artery (RIMA). All patients had uneventful postoperative stay and were discharged with a mean hospital stay of 3.8 days. There were no postoperative strokes, myocardial infarction, neurological symptoms, or change in EF. At 6-month follow-up, they were asymptomatic and doing well.

Conclusion: The RIMA-LIMA-Y configuration can be a safe, viable option in CABG for patients with left SAS. It is challenging, with re-entry and judicious utilization of the length of LIMA being of paramount importance. The importance of CT angiography of neck vessels to detect SAS cannot be under-emphasized.

背景:接受冠状动脉旁路移植术(CABG)的患者中,有 6% 会出现锁骨下动脉狭窄(SAS)。锁骨下-冠状动脉盗血等并发症很常见。此类病例的血管重建方案仍有争议:在本病例系列中,所有心绞痛患者在血管造影检查中都有严重的三支血管病变。所有检查包括颈部血管的计算机断层扫描(CT)血管造影术,都是作为 CABG 常规检查的一部分进行的:患者均为男性,平均年龄为 66.5 岁,其中三人患有高血压和糖尿病。所有患者均已戒烟,平均射血分数(EF)为 60.1%。颈部血管 CT 血管造影显示,两名患者患有中度至重度狭窄,一名患者患有重度左侧 SAS 狭窄,另一名患者患有重度左侧乳内动脉 (LIMA) 近端狭窄。患者接受了全动脉血管再造术,平均移植了 3.5 条远端动脉。LIMA 移植采用 Y 型结构,与原位右乳内动脉 (RIMA) 吻合。所有患者术后均顺利出院,平均住院时间为 3.8 天。术后未发生中风、心肌梗死、神经症状或 EF 变化。随访6个月时,他们均无症状,情况良好:结论:RIMA-LIMA-Y配置是左侧SAS患者进行CABG的一种安全可行的选择。它具有挑战性,再次入路和合理利用 LIMA 长度至关重要。颈部血管 CT 血管造影对检测 SAS 的重要性不容忽视。
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引用次数: 0
Accidental finding of ALCAPA in a child with severe mitral regurgitation: A case study. 一名患有严重二尖瓣返流的儿童意外发现 ALCAPA:病例研究。
IF 0.7 Q3 Medicine Pub Date : 2024-11-03 DOI: 10.1177/02184923241295550
Budi Rahmat, Radityo Prakoso, Rafles Ph Simbolon, Albert T Lopolisa, Muhammad Rayhan, Eva M Marwali

Case report: A six-year-old child who had undergone cardiac surgery five years ago presented to us with severe mitral valve regurgitation. During her current surgery, the coronary artery was injured during the attempt to release extensive epicardial adhesion, resulting in very poor contractility that prompted a delay in the intended valve repair. The injured coronary vessels were successfully repaired, yet low cardiac output syndrome persisted during perioperative care, necessitating further investigation of the coronary problem. It was later discovered that the patient had anomalous left coronary artery from pulmonary artery (ALCAPA) syndrome.

Discussion: The presence of severe mitral regurgitation, pulmonary hypertension, and anatomical factors may have contributed to the delayed presentation and diagnosis in this case. The severity of mitral regurgitation and the most likely underlying mechanism indicates a low possibility of recovery following coronary repair alone, warranting the need for concomitant mitral surgery. Coronary and mitral repair were performed in this patient, resulting in a favorable outcome.

Conclusions: The management of ALCAPA presents unique challenges, especially in cases with delayed diagnosis. Proper diagnosis and tailored surgical approaches are crucial for achieving favorable outcomes in patients with ALCAPA.

病例报告一名六岁儿童五年前曾接受过心脏手术,现因严重的二尖瓣返流来我院就诊。在目前的手术中,她的冠状动脉在试图松解广泛的心外膜粘连时受伤,导致收缩力极差,从而延误了预定的瓣膜修复手术。受伤的冠状动脉已成功修复,但围术期护理期间仍存在低心输出量综合征,因此有必要进一步检查冠状动脉问题。后来发现患者患有肺动脉左冠状动脉异常(ALCAPA)综合征:讨论:严重二尖瓣反流、肺动脉高压和解剖学因素可能是导致该病例延迟出现和诊断的原因。二尖瓣反流的严重程度和最可能的潜在机制表明,单靠冠状动脉修补术恢复的可能性很低,因此需要同时进行二尖瓣手术。该患者接受了冠状动脉和二尖瓣修复术,结果良好:结论:ALCAPA的治疗面临独特的挑战,尤其是在诊断延迟的病例中。正确的诊断和有针对性的手术方法是ALCAPA患者获得良好预后的关键。
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引用次数: 0
Coronary arteriovenous fistula originating from the left coronary artery and draining into the superior vena cava. 冠状动静脉瘘源自左冠状动脉,引流至上腔静脉。
IF 0.7 Q3 Medicine Pub Date : 2024-11-03 DOI: 10.1177/02184923241296166
Airi Kageyama, Takayuki Saito

Coronary arteriovenous fistulas are rare coronary anomalies. Most fistulas arise from the right coronary artery and drain into the right heart structures. We report a case of a 59-year-old man with a rare coronary arteriovenous fistula that originates from the left coronary artery and drains into the superior vena cava. He was diagnosed incidentally with cardiac computed tomography during the investigation for atrial fibrillation. Surgical fistula ligation was successfully performed under cardiac arrest with cardiopulmonary bypass. The patient was discharged without complications.

冠状动脉动静脉瘘是一种罕见的冠状动脉畸形。大多数瘘管来自右冠状动脉,并排入右心结构。我们报告了一例 59 岁男性罕见冠状动静脉瘘病例,该瘘源自左冠状动脉,引流至上腔静脉。他是在检查心房颤动时偶然通过心脏计算机断层扫描确诊的。在心搏停止和心肺旁路的情况下,成功进行了瘘管结扎手术。患者无并发症出院。
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引用次数: 0
Outcomes of fenestration versus none in extracardiac total cavopulmonary connection. 在心外全腔肺连接中进行瓣膜置入术与不进行瓣膜置入术的结果。
IF 0.7 Q3 Medicine Pub Date : 2024-10-23 DOI: 10.1177/02184923241292688
Noppon Taksaudom, Jakaparn Horsatidkul, Thitipong Tepsuwan, Apichat Tantraworasin, Rekwan Sittiwangkul, Amarit Phothikun

Background: Fenestrated total cavopulmonary connection has gained popularity due to its capacity to reduce systemic venous pressure and enhance cardiac output. However, there is ongoing debate about the immediate and long-term advantages of fenestration in this context.

Method: A retrospective cohort study was conducted involving 97 patients who underwent extracardiac total cavopulmonary connection at Chiang Mai University Hospital between January 1999 and December 2019. The patients were initially categorized into two groups: fenestrated (n = 71) and nonfenestrated (n = 26). After exclusion and reassignment, the long-term outcomes were analyzed for the fenestrated (n = 68) and nonfenestrated (n = 25) groups. To address potential confounding factors between the two groups, propensity scores were computed using logistic regression analysis.

Results: The study found no significant differences in preoperative and operative data. Immediate postoperative outcomes showed no significant variations in major complications, intensive care unit stay, oxygen saturation, and posttotal cavopulmonary connection pressure. In the long-term assessment, the fenestrated group demonstrated significantly lower rates of mortality, protein-losing enteropathy, liver mass, and cirrhosis. However, after employing a multilevel model stratified by propensity score analysis, only long-term mortality rate was significantly lower in the fenestrated group (hazard ratio = 0.12, 95% confidence interval = 0.02-0.97). Fenestration patency closed gradually through spontaneous closure and device intervention.

Conclusion: The study found no major differences in immediate postoperative outcomes. In the fenestrated cohort, significantly lower incidences of protein-losing enteropathy, liver mass, cirrhosis, and long-term mortality were observed. However, multilevel model stratified by propensity score analysis indicated that only the lower long-term mortality demonstrated a major effect.

背景:瓣膜全腔肺连接术因其能降低全身静脉压和提高心输出量而受到欢迎。然而,在这种情况下,关于瓣膜的近期和远期优势一直存在争议:一项回顾性队列研究涉及 1999 年 1 月至 2019 年 12 月期间在清迈大学医院接受心外全腔肺连接术的 97 名患者。这些患者最初被分为两组:有瘘管(71 人)和无瘘管(26 人)。在排除和重新分配后,对开窗组(n = 68)和非开窗组(n = 25)的长期结果进行了分析。为了解决两组之间潜在的混杂因素,研究人员使用逻辑回归分析法计算了倾向得分:研究发现,术前和手术数据无明显差异。术后近期结果显示,主要并发症、重症监护室住院时间、血氧饱和度和全腔肺连接后压力均无明显差异。在长期评估中,栅栏组的死亡率、蛋白丢失性肠病、肝脏肿块和肝硬化的发生率明显较低。然而,在采用倾向得分分析多层次模型分层后,只有瓣膜组的长期死亡率明显降低(危险比 = 0.12,95% 置信区间 = 0.02-0.97)。通过自发闭合和设备干预,瘘管通畅率逐渐关闭:结论:研究发现,术后即刻结果没有重大差异。结论:研究发现术后即刻预后无重大差异,但在瘘管队列中,蛋白质丢失性肠病、肝脏肿块、肝硬化和长期死亡率的发生率明显较低。然而,根据倾向得分分析建立的多层次分层模型表明,只有长期死亡率较低才显示出主要影响。
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引用次数: 0
Impact of preoperative computed tomography scan on neurological outcomes in coronary artery bypass grafting patients: A propensity-score analysis. 术前计算机断层扫描对冠状动脉旁路移植术患者神经系统预后的影响:倾向分数分析
IF 0.7 Q3 Medicine Pub Date : 2024-10-21 DOI: 10.1177/02184923241292098
Mariano Cefarelli, Pietro Giorgio Malvindi, Olimpia Bifulco, Beatrice Buratto, Paolo Berretta, Carlo Zingaro, Filippo Capestro, Michele Danilo Pierri, Jacopo Alfonsi, Alessandro D'Alfonso, Marco Di Eusanio

Introduction: Neurological complications pose significant risks in coronary artery bypass grafting (CABG). This study explores the potential benefits of preoperative chest computed tomography (CT) in optimizing outcomes and reducing neurological events in high-risk CABG patients.

Methods: From January 2017 to June 2023, a retrospective cohort study of CABG patients categorized groups based on preoperative chest CT use. Multivariate analysis evaluated the associations between CT imaging and patient characteristics, followed by propensity match analysis to balance preoperative features across groups.

Results: The study included 1786 patients, with 435 having undergone preoperative CT and 1351 without. Propensity matching created two well-balanced groups of 413 patients each. At multivariate analysis, CT patients were elderly (71.1 ± 8.9 years; p = 0.03) with a higher incidence of pulmonary disease (19.5%; p < 0.01), peripheral arterial disease (29.2%; p < 0.01), and previous cerebrovascular disease (23.4%; p = 0.02). In the matched CT cohort, the perioperative cerebral stroke rate was 0.7% (vs. 1.9% in without preoperative CT [WCT] cohort; p = 0.223), and the 30-day mortality rate was 0.2% (vs. 1.7% in WCT cohort; p = 0.069). Patients who had a preoperative CT study presented a higher prevalence of porcelain aorta (6.3% vs. 1.5%; p = 0.0003) and required more often a no-touch aorta procedure (20.3% vs. 14.5%; p = 0.035).

Conclusions: Patients undergoing preoperative chest CT before CABG were typically older and had systemic atherosclerosis and pulmonary disease. Propensity-matched analysis indicated low mortality and perioperative cerebral stroke rates in these high-risk patients. These findings support the integration of chest CT into preoperative evaluations for high-risk patients to develop tailored strategies in coronary artery bypass surgery.

导言:神经系统并发症是冠状动脉旁路移植术(CABG)的重大风险。本研究探讨了术前胸部计算机断层扫描(CT)在优化高风险 CABG 患者预后和减少神经系统事件方面的潜在益处:从 2017 年 1 月到 2023 年 6 月,一项对 CABG 患者的回顾性队列研究根据术前胸部 CT 的使用情况进行了分组。多变量分析评估了CT成像与患者特征之间的关联,然后进行倾向匹配分析,以平衡各组患者的术前特征:该研究共纳入了 1786 名患者,其中 435 人接受了术前 CT 检查,1351 人未接受术前 CT 检查。倾向匹配产生了两组均衡的患者,每组 413 人。多变量分析显示,CT 患者年龄较大(71.1 ± 8.9 岁;P = 0.03),肺部疾病发病率较高(19.5%;P = 0.02)。在匹配的 CT 队列中,围手术期脑卒中发生率为 0.7%(与未进行术前 CT [WCT] 队列中的 1.9%相比;P = 0.223),30 天死亡率为 0.2%(与 WCT 队列中的 1.7%相比;P = 0.069)。接受术前 CT 检查的患者主动脉瓷化的发生率更高(6.3% 对 1.5%;P = 0.0003),需要进行无触点主动脉手术的比例更高(20.3% 对 14.5%;P = 0.035):结论:接受 CABG 术前胸部 CT 的患者通常年龄较大,患有全身动脉粥样硬化和肺部疾病。倾向匹配分析表明,这些高危患者的死亡率和围手术期脑卒中发生率较低。这些研究结果支持将胸部 CT 纳入高危患者的术前评估,以便为冠状动脉搭桥手术制定有针对性的策略。
{"title":"Impact of preoperative computed tomography scan on neurological outcomes in coronary artery bypass grafting patients: A propensity-score analysis.","authors":"Mariano Cefarelli, Pietro Giorgio Malvindi, Olimpia Bifulco, Beatrice Buratto, Paolo Berretta, Carlo Zingaro, Filippo Capestro, Michele Danilo Pierri, Jacopo Alfonsi, Alessandro D'Alfonso, Marco Di Eusanio","doi":"10.1177/02184923241292098","DOIUrl":"https://doi.org/10.1177/02184923241292098","url":null,"abstract":"<p><strong>Introduction: </strong>Neurological complications pose significant risks in coronary artery bypass grafting (CABG). This study explores the potential benefits of preoperative chest computed tomography (CT) in optimizing outcomes and reducing neurological events in high-risk CABG patients.</p><p><strong>Methods: </strong>From January 2017 to June 2023, a retrospective cohort study of CABG patients categorized groups based on preoperative chest CT use. Multivariate analysis evaluated the associations between CT imaging and patient characteristics, followed by propensity match analysis to balance preoperative features across groups.</p><p><strong>Results: </strong>The study included 1786 patients, with 435 having undergone preoperative CT and 1351 without. Propensity matching created two well-balanced groups of 413 patients each. At multivariate analysis, CT patients were elderly (71.1 ± 8.9 years; <i>p </i>= 0.03) with a higher incidence of pulmonary disease (19.5%; <i>p </i>< 0.01), peripheral arterial disease (29.2%; <i>p </i>< 0.01), and previous cerebrovascular disease (23.4%; <i>p </i>= 0.02). In the matched CT cohort, the perioperative cerebral stroke rate was 0.7% (vs. 1.9% in without preoperative CT [WCT] cohort; <i>p </i>= 0.223), and the 30-day mortality rate was 0.2% (vs. 1.7% in WCT cohort; <i>p </i>= 0.069). Patients who had a preoperative CT study presented a higher prevalence of porcelain aorta (6.3% vs. 1.5%; <i>p </i>= 0.0003) and required more often a no-touch aorta procedure (20.3% vs. 14.5%; <i>p </i>= 0.035).</p><p><strong>Conclusions: </strong>Patients undergoing preoperative chest CT before CABG were typically older and had systemic atherosclerosis and pulmonary disease. Propensity-matched analysis indicated low mortality and perioperative cerebral stroke rates in these high-risk patients. These findings support the integration of chest CT into preoperative evaluations for high-risk patients to develop tailored strategies in coronary artery bypass surgery.</p>","PeriodicalId":35950,"journal":{"name":"ASIAN CARDIOVASCULAR & THORACIC ANNALS","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142476630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful repair of infracardiac total anomalous pulmonary venous connection with nonconfluent bilateral pulmonary veins. 双侧肺静脉不汇合的心下全肺静脉连接异常修复手术获得成功。
IF 0.7 Q3 Medicine Pub Date : 2024-10-17 DOI: 10.1177/02184923241291917
Tomonori Ochiai, Hideki Tatewaki, Naoki Masaki, Sadahiro Sai

We report a rare case of an infracardiac-type total anomalous pulmonary venous connection with nonconfluent bilateral pulmonary veins in a patient diagnosed with heterotaxy syndrome with right atrial isomerism, mitral valve atresia, a single atrium, and double-outlet right ventricle. On the fourth day of life, the patient underwent successful repair using a sutureless technique. Two years after the surgery, the patient remained well without any signs of pulmonary venous obstruction.

我们报告了一例罕见的心下型全肺静脉连接异常和双侧肺静脉非汇合病例,患者被诊断为异位发育综合征,伴有右心房异位、二尖瓣闭锁、单心房和右心室双出口。患者出生后第四天,成功接受了无缝合技术修复手术。术后两年,患者的情况依然良好,没有任何肺静脉阻塞的迹象。
{"title":"Successful repair of infracardiac total anomalous pulmonary venous connection with nonconfluent bilateral pulmonary veins.","authors":"Tomonori Ochiai, Hideki Tatewaki, Naoki Masaki, Sadahiro Sai","doi":"10.1177/02184923241291917","DOIUrl":"https://doi.org/10.1177/02184923241291917","url":null,"abstract":"<p><p>We report a rare case of an infracardiac-type total anomalous pulmonary venous connection with nonconfluent bilateral pulmonary veins in a patient diagnosed with heterotaxy syndrome with right atrial isomerism, mitral valve atresia, a single atrium, and double-outlet right ventricle. On the fourth day of life, the patient underwent successful repair using a sutureless technique. Two years after the surgery, the patient remained well without any signs of pulmonary venous obstruction.</p>","PeriodicalId":35950,"journal":{"name":"ASIAN CARDIOVASCULAR & THORACIC ANNALS","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142476631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Short-term exercise training benefits pulmonary arterial hypertension patients. 短期运动训练有益于肺动脉高压患者。
IF 0.7 Q3 Medicine Pub Date : 2024-09-18 DOI: 10.1177/02184923241283979
Muhammad Zakiy Azzuhdi, Citra Kiki Krevani, Kino Kino

Objectives: Studies have shown exercise rehabilitation training improves exercise tolerance in pulmonary arterial hypertension (PAH) patients. However, implementing such programs in developing countries can be challenging. We investigated the benefits of short-term exercise rehabilitation training for PAH patients in a developing country.

Methods: This study was a prospective study of adult PAH patients attending the cardiology outpatient unit of a tertiary referral hospital. The patients were equally divided into an intervention group and a control group. We measured hemodynamic characteristics and six-minute walking distance (6MWD) before and after four weeks of exercise rehabilitation training. The Shapiro-Wilk normality test was performed, followed by an independent t-test or Mann-Whitney test to statistically compare the data.

Results: We included 28 patients aged 29.1 ± 11 years. We found no significant differences in all hemodynamic characteristics between the groups before and after the rehabilitation (all p-values >0.05). The intervention group showed a significant increase in 6MWD (300.6 ± 90.8 (95% CI: 248.2, 352.9) vs 436.3 ± 58.8 (95% CI: 402.3, 470.2), p-value <0.001) and consequently, the Δ6MWD in the intervention group was remarkably higher (17.1 ± 48.3 (95% CI: -10.8, 44.9) vs 115.36 ± 54.69 m (95% CI: 83.8, 146.9), p-value <0.001).

Conclusion: A short-term exercise rehabilitation training safely improved the exercise tolerance of patients with PAH. Our findings may lead to the improvement of rehabilitation strategies for this detrimental disease in countries with limited resources.

研究目的研究表明,运动康复训练可提高肺动脉高压(PAH)患者的运动耐量。然而,在发展中国家实施此类计划可能具有挑战性。我们调查了发展中国家的 PAH 患者接受短期运动康复训练的益处:本研究是一项前瞻性研究,对象是在一家三级转诊医院心脏科门诊就诊的成年 PAH 患者。患者平均分为干预组和对照组。我们测量了运动康复训练四周前后的血液动力学特征和六分钟步行距离(6MWD)。对数据进行 Shapiro-Wilk 正态性检验,然后进行独立 t 检验或 Mann-Whitney 检验,以对数据进行统计比较:我们共纳入 28 名患者,年龄为 29.1 ± 11 岁。我们发现,康复前后各组之间的所有血液动力学特征均无明显差异(所有 p 值均大于 0.05)。干预组的 6MWD 明显增加(300.6 ± 90.8 (95% CI: 248.2, 352.9) vs 436.3 ± 58.8 (95% CI: 402.3, 470.2), p-value p-value 结论:短期运动康复训练可安全改善 PAH 患者的运动耐量。我们的研究结果可帮助资源有限的国家改进针对这种有害疾病的康复策略。
{"title":"Short-term exercise training benefits pulmonary arterial hypertension patients.","authors":"Muhammad Zakiy Azzuhdi, Citra Kiki Krevani, Kino Kino","doi":"10.1177/02184923241283979","DOIUrl":"https://doi.org/10.1177/02184923241283979","url":null,"abstract":"<p><strong>Objectives: </strong>Studies have shown exercise rehabilitation training improves exercise tolerance in pulmonary arterial hypertension (PAH) patients. However, implementing such programs in developing countries can be challenging. We investigated the benefits of short-term exercise rehabilitation training for PAH patients in a developing country.</p><p><strong>Methods: </strong>This study was a prospective study of adult PAH patients attending the cardiology outpatient unit of a tertiary referral hospital. The patients were equally divided into an intervention group and a control group. We measured hemodynamic characteristics and six-minute walking distance (6MWD) before and after four weeks of exercise rehabilitation training. The Shapiro-Wilk normality test was performed, followed by an independent <i>t</i>-test or Mann-Whitney test to statistically compare the data.</p><p><strong>Results: </strong>We included 28 patients aged 29.1 ± 11 years. We found no significant differences in all hemodynamic characteristics between the groups before and after the rehabilitation (all <i>p</i>-values >0.05). The intervention group showed a significant increase in 6MWD (300.6 ± 90.8 (95% CI: 248.2, 352.9) vs 436.3 ± 58.8 (95% CI: 402.3, 470.2), <i>p</i>-value <0.001) and consequently, the Δ6MWD in the intervention group was remarkably higher (17.1 ± 48.3 (95% CI: -10.8, 44.9) vs 115.36 ± 54.69 m (95% CI: 83.8, 146.9), <i>p</i>-value <0.001).</p><p><strong>Conclusion: </strong>A short-term exercise rehabilitation training safely improved the exercise tolerance of patients with PAH. Our findings may lead to the improvement of rehabilitation strategies for this detrimental disease in countries with limited resources.</p>","PeriodicalId":35950,"journal":{"name":"ASIAN CARDIOVASCULAR & THORACIC ANNALS","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142297263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient satisfaction after Nuss procedure with one or two bars in young adults: A propensity score-matched cohort study. 青壮年接受一杠或两杠努斯手术后的患者满意度:倾向得分匹配队列研究。
IF 0.7 Q3 Medicine Pub Date : 2024-08-12 DOI: 10.1177/02184923241272887
Alessio Campisi, Riccardo Giovannetti, Giovanni Falezza, Emanuele Voulaz, Alessandro Lonardoni, Maurizio Valentino Infante

Background: The Nuss procedure is the primary treatment for pectus excavatum (PE), but patient expectations are not always met. In our unit, our standard approach in the last few years has been the routine application of two bars instead of one. We aimed to retrospectively assess the impact of this approach on patient satisfaction, quality of life (QoL) and safety.

Methods: A retrospective study included 182 patients over 16 years old who underwent the Nuss procedure for PE between January 2007 and September 2021. Patients were categorized into one-bar or two-bar correction groups. Propensity score matching (PSM) was used, resulting in 30 patients in each group. Primary endpoints were QoL and cosmetic satisfaction, while secondary endpoints included complications and recurrence.

Results: After PSM, both groups showed similar general characteristics. Patients treated with two bars reported fewer psychological complaints post-surgery (93.3% vs. 73.3%, p = 0.031). There were no significant differences in QoL improvement (96.7% in both groups, p = 0.197), perioperative complications (p = 0.771) or recurrence (one patient in the one-bar group, p = 1.000).

Conclusions: Our study reveals that patients undergoing the Nuss Procedure for PE with two bars exhibit comparable clinical outcomes and QoL to those with one bar. However, patients with two bars may have higher levels of psychological well-being and satisfaction, indicating potential benefits associated with this approach. These findings suggest potential advantages of the two-bar approach, but further research with larger sample sizes is warranted to confirm these observations.

背景:努氏手术是治疗胸大肌(PE)的主要方法,但并非总能满足患者的期望。在我们科室,过去几年的标准方法是常规应用两根横杆而不是一根。我们的目的是回顾性评估这种方法对患者满意度、生活质量(QoL)和安全性的影响:一项回顾性研究纳入了 2007 年 1 月至 2021 年 9 月间接受 Nuss 手术治疗 PE 的 182 名 16 岁以上患者。患者被分为单杠或双杠矫正组。采用倾向评分匹配法(PSM),每组 30 名患者。主要终点是生活质量和外观满意度,次要终点包括并发症和复发:经过 PSM 分析,两组患者的总体特征相似。接受双杠治疗的患者术后的心理抱怨较少(93.3% 对 73.3%,P = 0.031)。在生活质量改善(两组均为96.7%,p = 0.197)、围手术期并发症(p = 0.771)或复发(单杠组有一名患者,p = 1.000)方面没有明显差异:我们的研究表明,接受 Nuss 手术治疗 PE 的患者中,双杠患者的临床疗效和生活质量与单杠患者相当。然而,使用双杠的患者可能具有更高的心理健康水平和满意度,这表明这种方法具有潜在的益处。这些研究结果表明了双杠法的潜在优势,但要证实这些观察结果,还需要进行样本量更大的进一步研究。
{"title":"Patient satisfaction after Nuss procedure with one or two bars in young adults: A propensity score-matched cohort study.","authors":"Alessio Campisi, Riccardo Giovannetti, Giovanni Falezza, Emanuele Voulaz, Alessandro Lonardoni, Maurizio Valentino Infante","doi":"10.1177/02184923241272887","DOIUrl":"https://doi.org/10.1177/02184923241272887","url":null,"abstract":"<p><strong>Background: </strong>The Nuss procedure is the primary treatment for pectus excavatum (PE), but patient expectations are not always met. In our unit, our standard approach in the last few years has been the routine application of two bars instead of one. We aimed to retrospectively assess the impact of this approach on patient satisfaction, quality of life (QoL) and safety.</p><p><strong>Methods: </strong>A retrospective study included 182 patients over 16 years old who underwent the Nuss procedure for PE between January 2007 and September 2021. Patients were categorized into one-bar or two-bar correction groups. Propensity score matching (PSM) was used, resulting in 30 patients in each group. Primary endpoints were QoL and cosmetic satisfaction, while secondary endpoints included complications and recurrence.</p><p><strong>Results: </strong>After PSM, both groups showed similar general characteristics. Patients treated with two bars reported fewer psychological complaints post-surgery (93.3% vs. 73.3%, <i>p</i> = 0.031). There were no significant differences in QoL improvement (96.7% in both groups, <i>p</i> = 0.197), perioperative complications (<i>p</i> = 0.771) or recurrence (one patient in the one-bar group, <i>p</i> = 1.000).</p><p><strong>Conclusions: </strong>Our study reveals that patients undergoing the Nuss Procedure for PE with two bars exhibit comparable clinical outcomes and QoL to those with one bar. However, patients with two bars may have higher levels of psychological well-being and satisfaction, indicating potential benefits associated with this approach. These findings suggest potential advantages of the two-bar approach, but further research with larger sample sizes is warranted to confirm these observations.</p>","PeriodicalId":35950,"journal":{"name":"ASIAN CARDIOVASCULAR & THORACIC ANNALS","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141971961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk factors for postoperative acute pancreatitis after thoracic aortic surgery. 胸主动脉手术后急性胰腺炎的风险因素。
IF 0.7 Q3 Medicine Pub Date : 2024-07-25 DOI: 10.1177/02184923241263919
Ryoma Ueda, Jiro Esaki, Hideki Tsubota, Masanori Honda, Masafumi Kudo, Takehiko Matsuo, Hitoshi Okabayashi

Background: We aimed to investigate the incidence and risk factors of postoperative acute pancreatitis (PAP) following thoracic aortic surgery with circulatory arrest.

Methods: One hundred fifty-two patients who underwent thoracic aortic surgery with circulatory arrest between February 2015 and March 2023 were retrospectively reviewed. Postoperative acute pancreatitis was defined as the presence of two or more of the following criteria: (1) abdominal pain, (2) postoperative amylase or lipase levels greater than three times the upper limit of normal, and (3) evidence of pancreatitis on postoperative computed tomography (CT) scan. Univariate and multivariate analyses were performed to find risk factors for PAP.

Results: Nine patients (5.9%) developed PAP without mortality. All of the nine patients had elevated pancreatic enzymes and evidence of pancreatitis on CT. They improved with conservative therapy. In multivariate analysis, only cross-clamp time was found to be a significant risk factor for PAP (adjusted odds ratio, 1.04; 95% confidence interval, 1-1.08; p = 0.042).

Conclusion: The incidence of PAP after thoracic aortic surgery with circulatory arrest was 5.9%, and cross-clamp time is an independent risk factor for PAP.

背景:我们的目的是研究胸主动脉手术后循环停止的术后急性胰腺炎(PAP)的发生率和风险因素:我们旨在研究胸主动脉手术后循环停止状态下术后急性胰腺炎(PAP)的发生率和风险因素:回顾性研究了 2015 年 2 月至 2023 年 3 月期间接受胸主动脉手术并停循环的 152 例患者。术后急性胰腺炎定义为出现以下两个或两个以上标准:(1)腹痛;(2)术后淀粉酶或脂肪酶水平超过正常值上限的三倍;(3)术后计算机断层扫描(CT)有胰腺炎的证据。通过单变量和多变量分析找出胰腺炎的风险因素:结果:9 名患者(5.9%)出现胰腺炎,但无死亡病例。九名患者(5.9%)均有胰酶升高和 CT 显示胰腺炎。他们在接受保守治疗后病情有所好转。在多变量分析中,发现只有交叉钳夹时间是 PAP 的重要风险因素(调整后的几率比为 1.04;95% 置信区间为 1-1.08;P = 0.042):结论:循环停止的胸主动脉手术后 PAP 发生率为 5.9%,交叉钳夹时间是 PAP 的独立风险因素。
{"title":"Risk factors for postoperative acute pancreatitis after thoracic aortic surgery.","authors":"Ryoma Ueda, Jiro Esaki, Hideki Tsubota, Masanori Honda, Masafumi Kudo, Takehiko Matsuo, Hitoshi Okabayashi","doi":"10.1177/02184923241263919","DOIUrl":"https://doi.org/10.1177/02184923241263919","url":null,"abstract":"<p><strong>Background: </strong>We aimed to investigate the incidence and risk factors of postoperative acute pancreatitis (PAP) following thoracic aortic surgery with circulatory arrest.</p><p><strong>Methods: </strong>One hundred fifty-two patients who underwent thoracic aortic surgery with circulatory arrest between February 2015 and March 2023 were retrospectively reviewed. Postoperative acute pancreatitis was defined as the presence of two or more of the following criteria: (1) abdominal pain, (2) postoperative amylase or lipase levels greater than three times the upper limit of normal, and (3) evidence of pancreatitis on postoperative computed tomography (CT) scan. Univariate and multivariate analyses were performed to find risk factors for PAP.</p><p><strong>Results: </strong>Nine patients (5.9%) developed PAP without mortality. All of the nine patients had elevated pancreatic enzymes and evidence of pancreatitis on CT. They improved with conservative therapy. In multivariate analysis, only cross-clamp time was found to be a significant risk factor for PAP (adjusted odds ratio, 1.04; 95% confidence interval, 1-1.08; <i>p</i> = 0.042).</p><p><strong>Conclusion: </strong>The incidence of PAP after thoracic aortic surgery with circulatory arrest was 5.9%, and cross-clamp time is an independent risk factor for PAP.</p>","PeriodicalId":35950,"journal":{"name":"ASIAN CARDIOVASCULAR & THORACIC ANNALS","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141761441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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