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The usefulness of staged extra-anatomic bypass for coarctation of the aorta with arch hypoplasia, from premature neonate to adult. 从早产新生儿到成人主动脉弓发育不良的分期体外搭桥术的实用性。
IF 0.7 Q3 Medicine Pub Date : 2024-05-01 Epub Date: 2024-03-14 DOI: 10.1177/02184923241240184
Toshiaki Nagashima, Masaki Taira, Moyu Hasegawa, Yosuke Kugo, Takuji Watanabe, Shigeru Miyagawa

Various surgical techniques have been developed for coarctation of the aorta. However, coarctation repair in neonates with arch hypoplasia remains challenging. We herein report a case in which a premature neonate under 1500 g with coarctation of the aorta and arch hypoplasia underwent an extra-anatomical bypass at 18 days old. A second extra-anatomical bypass was performed at 3 years of age, and a third extra-anatomic bypass for recurrent coarctation was performed in adulthood. By increasing the size of the graft as the patient grows, extra-anatomic bypass can be a useful surgical option for premature neonates with coarctation and arch hypoplasia.

目前已开发出多种治疗主动脉闭塞的手术技术。然而,在拱部发育不良的新生儿中进行主动脉弓闭塞修复仍具有挑战性。我们在此报告了一例体重不足 1500 克、患有主动脉弓发育不全的早产新生儿,他在出生 18 天时接受了解剖外搭桥术。3 岁时进行了第二次解剖外搭桥术,成年后又因复发性大动脉闭塞进行了第三次解剖外搭桥术。通过随着患者的成长而增大移植物的尺寸,解剖外搭桥术可以成为患有并发症和心弓发育不良的早产新生儿的有效手术选择。
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引用次数: 0
Continuous Glucose Monitoring System After Coronary Artery Bypass Graft Surgery: A Feasibility Study. 冠状动脉旁路移植手术后的连续血糖监测系统:可行性研究
IF 0.7 Q3 Medicine Pub Date : 2024-05-01 Epub Date: 2024-03-20 DOI: 10.1177/02184923241240035
Tiziano Torre, Hervé Schlotterbeck, Francesco Ferraro, Catherine Klersy, Giuseppina Surace, Francesca Toto, Alberto Pozzoli, Enrico Ferrari, Stefanos Demertzis

Background: Blood glucose level variability has been associated with increased risk of complication in the postoperative setting of cardiovascular surgery. Although interesting for optimization of blood glucose management in this context, continuous blood glucose (CBG) devices can have a limited reliability in this context, in particular because of the use of paracetamol. The aim of this study was to evaluate the reliability of Dexcom G6®, a recently developed continuous glucose monitoring device.

Methods: We performed a prospective, observational, non-randomized, single-centre study comparing Dexcom G6® CBG level monitoring with the standard methods routinely used in this context. The standard blood glucose values were paired to the time corresponding values measured with Dexcom G6®. Agreement between the two methods and potential correlation in case of paracetamol use were calculated.

Results: From May 2020 to August 2021, 36 out of 206 patients operated for isolated coronary artery bypass grafting were enrolled; 673 paired blood glucose level were analyzed. Global agreement (ρc) was 0.85 (95% C.I.: 0.84-0.86), intensive care unit agreement was 0.78 (95%C.I.: 0.74-0.82) and ward agreement was 0.91 (95%C.I.: 0.89-0.93). In the diabetic population, it was 0.87 (95%C.I.: 0.85-0.90). When paracetamol was used, the difference was 0.02 mmol/l (95%C.I.: 0.29-0.33).

Conclusions: Dexcom G6® provides good blood glucose level accuracy in the postoperative context of cardiac surgery compared to the standard methods of measurements. The results are particularly reliable in the ward where the need for repeated capillary glucose measurements implies patient discomfort and time-consuming manipulations for the nursing staff.

背景:血糖水平的变化与心血管手术术后并发症风险的增加有关。虽然在这种情况下优化血糖管理很有意义,但在这种情况下连续血糖监测设备的可靠性有限,特别是在使用扑热息痛的情况下。本研究旨在评估最近开发的连续血糖监测设备 Dexcom G6® 的可靠性:我们进行了一项前瞻性、观察性、非随机、单中心研究,将 Dexcom G6® CBG 水平监测与在这种情况下常规使用的标准方法进行比较。标准血糖值与 Dexcom G6® 测量的时间对应值配对。计算了两种方法之间的一致性以及在使用扑热息痛的情况下可能存在的相关性:从 2020 年 5 月到 2021 年 8 月,在 206 名接受孤立冠状动脉旁路移植手术的患者中,有 36 人接受了治疗;对 673 个配对血糖值进行了分析。全球一致性(ρc)为 0.85(95% C.I.:0.84-0.86),重症监护室一致性为 0.78(95% C.I.:0.74-0.82),病房一致性为 0.91(95% C.I.:0.89-0.93)。在糖尿病患者群体中,一致性为 0.87 (95%C.I.: 0.85-0.90)。使用扑热息痛时,差异为 0.02 mmol/l(95%C.I.:0.29-0.33):结论:与标准测量方法相比,Dexcom G6® 可为心脏手术术后血糖水平提供良好的准确性。其结果在病房中尤为可靠,因为在病房中需要反复测量毛细血管血糖,这意味着病人会感到不适,护理人员的操作也很耗时。
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引用次数: 0
Lack of awareness of secondary rheumatic prevention in preoperative candidates for mitral valve surgery - alarming situation. 二尖瓣手术术前患者缺乏对风湿病二级预防的认识--这种情况令人担忧。
IF 0.7 Q3 Medicine Pub Date : 2024-05-01 Epub Date: 2024-05-22 DOI: 10.1177/02184923241256409
Raheela Khowaja, Aamir Khowaja, Ali Raza Mangi, Ali Ammar, Waqar Khan, Nehrish Patel, Rabia Nizar, Munawar Khursheed, Jawaid Akbar Sial, Rizwan Aziz Memon

Background: We conducted this study to assess the compliance with secondary rheumatic prophylaxis among preoperative patients with rheumatic mitral valve disease undergoing valvular heart surgery at a tertiary care cardiac hospital in a developing country.

Methods: This is a descriptive cross-sectional study conducted at a tertiary care cardiac hospital in Karachi, Pakistan. The inclusion criteria encompassed patients of any sex, aged between 18 and 80 years, who had been diagnosed with rheumatic mitral valve disease through transthoracic echocardiography and had undergone valvular heart surgery. The level of compliance with secondary rheumatic prophylaxis and barriers toward noncompliance was assessed during routine preoperative interview session. This preventive measure plays a crucial role in reducing the progression of the disease and improving patient outcomes.

Results: Out of the 239 patients included in the study, 125 (52.3%) were females, with a mean age of 38.8 ± 11.8 years. The majority of patients (88.7%) came from rural areas. Among the patients, 79 (33.1%) received rheumatic prophylaxis, while 160 (66.9%) did not adhere to it regularly. The common barriers for receiving rheumatic prophylaxis were non availability (41.0%) and nonaffordability (40.6%). Additionally, 28.0% of patients had lacked awareness of the importance of rheumatic prophylaxis, and 2.5% expressed fear of injection site pain and subsequent symptoms.

Conclusions: A concerning level of noncompliance with secondary rheumatic prophylaxis was observed. The barriers identified in patients who did not receive rheumatic prophylaxis were primarily related to affordability, availability, lack of awareness, and fear of injection site pain and subsequent symptoms.

背景:我们进行了这项研究,以评估发展中国家一家三级心脏病医院接受瓣膜性心脏手术的风湿性二尖瓣疾病患者术前二次风湿预防的依从性:这是一项描述性横断面研究,在巴基斯坦卡拉奇的一家三级心脏病医院进行。纳入标准包括通过经胸超声心动图确诊患有风湿性二尖瓣疾病并接受过瓣膜性心脏手术的患者,年龄在 18 岁至 80 岁之间,性别不限。在术前的例行访谈中,对患者是否遵守二级风湿预防措施以及不遵守的障碍进行了评估。这一预防措施在减少疾病进展和改善患者预后方面起着至关重要的作用:在纳入研究的 239 名患者中,125 名(52.3%)为女性,平均年龄为(38.8±11.8)岁。大多数患者(88.7%)来自农村地区。患者中,79 人(33.1%)接受了风湿病预防治疗,160 人(66.9%)没有定期接受治疗。接受风湿预防的常见障碍是无法获得(41.0%)和负担不起(40.6%)。此外,28.0%的患者缺乏对风湿预防重要性的认识,2.5%的患者表示害怕注射部位疼痛和随后出现的症状:结论:我们观察到了不遵守二次风湿预防措施的严重程度。在未接受风湿预防治疗的患者中发现的障碍主要与经济能力、可用性、缺乏认识以及害怕注射部位疼痛和后续症状有关。
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引用次数: 0
Aortic versus axillary cannulation in acute type A aortic dissection repair: A meta-analysis. 急性 A 型主动脉夹层修复术中的主动脉插管与腋窝插管:荟萃分析
IF 0.7 Q3 Medicine Pub Date : 2024-05-01 Epub Date: 2024-02-11 DOI: 10.1177/02184923241232008
Yoshiyuki Yamashita, Serge Sicouri, Aleksander Dokollari, Roberto Rodriguez, Scott M Goldman, Basel Ramlawi

Background: Research comparing the effectiveness of central aortic cannulation to axillary artery cannulation in repairing acute type A aortic dissection is limited and controversial. This meta-analysis aimed to compare early outcomes of central aortic cannulation versus axillary artery cannulation for surgery for acute aortic dissection type A.

Methods: A comprehensive systematic search was conducted across PubMed/MEDLINE, Scopus, and the Cochrane Central Register of Controlled Trials up to September 1, 2023. The primary endpoints were operative mortality and incidence of postoperative stroke. Secondary endpoints encompassed cardiopulmonary bypass time, myocardial ischemic time, hypothermic circulatory arrest time, postoperative temporary neurological dysfunction, combination of stroke and temporary neurological dysfunction, as well as the need for reexploration for bleeding, renal replacement therapy, and tracheotomy. A random-effect model was utilized to calculate the pooled effect size.

Results: Eleven studies met our eligibility criteria, enrolling a total of 7204 patients (2760 underwent aortic cannulation and 4444 underwent axillary cannulation). The operative mortality and incidence of postoperative stroke did not show statistical differences between the two groups, with a pooled odds ratio of 1.07 (95% confidence interval: 0.73-1.55) and 1.17 (0.95-1.42), respectively. Similarly, none of the secondary endpoints exhibited significant statistical differences between the two groups.

Conclusions: Aortic cannulation can be a viable alternative to axillary artery cannulation for repair of acute aortic dissection type A, as both approaches present similar early clinical outcomes.

背景:在修复急性 A 型主动脉夹层时,比较中央主动脉插管与腋动脉插管的有效性的研究有限,且存在争议。本荟萃分析旨在比较中央主动脉插管与腋动脉插管在急性 A 型主动脉夹层手术中的早期疗效:在PubMed/MEDLINE、Scopus和截至2023年9月1日的Cochrane对照试验中央登记册中进行了全面的系统检索。主要终点是手术死亡率和术后中风发生率。次要终点包括心肺旁路时间、心肌缺血时间、低体温循环停止时间、术后暂时性神经功能障碍、中风和暂时性神经功能障碍的合并症,以及因出血、肾脏替代治疗和气管切开而再次探查的需要。采用随机效应模型计算汇总效应大小:有 11 项研究符合我们的资格标准,共纳入了 7204 名患者(2760 名接受了主动脉插管,4444 名接受了腋窝插管)。两组患者的手术死亡率和术后中风发生率没有统计学差异,汇总的几率比分别为 1.07(95% 置信区间:0.73-1.55)和 1.17(0.95-1.42)。同样,两组患者的次要终点均无明显统计学差异:主动脉插管可替代腋动脉插管用于急性主动脉夹层A型的修复,因为两种方法的早期临床效果相似。
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引用次数: 0
Siewert II esophagogastric junction adenocarcinoma: Still searching for the right treatment transabdominal or transthoracic surgical approaches? Siewert II 型食管胃交界处腺癌:仍在寻找正确的经腹或经胸手术治疗方法?
IF 0.7 Q3 Medicine Pub Date : 2024-05-01 Epub Date: 2024-03-28 DOI: 10.1177/02184923241238486
Mohamed Maatouk, Mariem Nouira, Anis Ben Dhaou, Ghassen Hamdi Kbir, Aymen Mabrouk, Mohamed Ben Khlifa, Sami Daldoul, Sofien Sayari, Mounir Ben Moussa

Introduction: To date, the discussion is still ongoing whether the Siewert II adenocarcinoma of the esophagogastric junction (AEG) should be resected either by thoracoabdominal esophagectomy or gastrectomy with resection of the distal esophagus by transhiatal extension. The aim of our study was to compare the oncological and perioperative outcomes of the transthoracic approach (TTA) and the transabdominal approach (TAA).

Methods: Searches of electronic databases identifying studies from Cochrane, PubMed and Google Scholar were performed. Randomised and non-randomised studies comparing TTA and TAA approaches for surgical treatment of AEG Siewert type II were included. The Newcastle-Ottawa and Jada scales were used to evaluate methodological quality. The risk of bias was assessed using the Rob v2 and Robins-I tools. Meta-analyses were conducted for the outcomes.

Results: We included 17 trials (2 randomised controlled trials and 15 cohorts) involving 15297 patients. Longer three-year overall survival, five-year overall survival and R0 resection rates were observed in the TTA group. However, TTA had greater morbidity and pulmonary complications.

Conclusion: Transthoracic approach appears to be preferable for selected Siewert II tumours. This may lead to higher survival rates and better R0 resection rate. Well-designed studies are needed to confirm the results of this systematic review.

导言:迄今为止,关于食管胃交界处(AEG)Siewert II 型腺癌是否应采用胸腹食管切除术或胃切除术并经食管远端延伸切除的讨论仍在继续。我们的研究旨在比较经胸方法(TTA)和经腹方法(TAA)的肿瘤学和围手术期结果:方法:对电子数据库进行检索,从 Cochrane、PubMed 和 Google Scholar 中查找相关研究。纳入了比较 TTA 和 TAA 手术治疗 AEG Siewert II 型的随机和非随机研究。采用纽卡斯尔-渥太华量表和贾达量表评估方法学质量。采用Rob v2和Robins-I工具评估偏倚风险。对结果进行了 Meta 分析:我们纳入了17项试验(2项随机对照试验和15项队列研究),涉及15297名患者。观察到TTA组的三年总生存期、五年总生存期和R0切除率更长。然而,TTA的发病率和肺部并发症更高:结论:对于选定的Siewert II型肿瘤,经胸方法似乎更可取。结论:对于选定的 Siewert II 型肿瘤,经胸入路似乎更可取,这可能会带来更高的生存率和更好的 R0 切除率。需要设计良好的研究来证实本系统综述的结果。
{"title":"Siewert II esophagogastric junction adenocarcinoma: Still searching for the right treatment transabdominal or transthoracic surgical approaches?","authors":"Mohamed Maatouk, Mariem Nouira, Anis Ben Dhaou, Ghassen Hamdi Kbir, Aymen Mabrouk, Mohamed Ben Khlifa, Sami Daldoul, Sofien Sayari, Mounir Ben Moussa","doi":"10.1177/02184923241238486","DOIUrl":"10.1177/02184923241238486","url":null,"abstract":"<p><strong>Introduction: </strong>To date, the discussion is still ongoing whether the Siewert II adenocarcinoma of the esophagogastric junction (AEG) should be resected either by thoracoabdominal esophagectomy or gastrectomy with resection of the distal esophagus by transhiatal extension. The aim of our study was to compare the oncological and perioperative outcomes of the transthoracic approach (TTA) and the transabdominal approach (TAA).</p><p><strong>Methods: </strong>Searches of electronic databases identifying studies from Cochrane, PubMed and Google Scholar were performed. Randomised and non-randomised studies comparing TTA and TAA approaches for surgical treatment of AEG Siewert type II were included. The Newcastle-Ottawa and Jada scales were used to evaluate methodological quality. The risk of bias was assessed using the Rob v2 and Robins-I tools. Meta-analyses were conducted for the outcomes.</p><p><strong>Results: </strong>We included 17 trials (2 randomised controlled trials and 15 cohorts) involving 15297 patients. Longer three-year overall survival, five-year overall survival and R0 resection rates were observed in the TTA group. However, TTA had greater morbidity and pulmonary complications.</p><p><strong>Conclusion: </strong>Transthoracic approach appears to be preferable for selected Siewert II tumours. This may lead to higher survival rates and better R0 resection rate. Well-designed studies are needed to confirm the results of this systematic review.</p>","PeriodicalId":35950,"journal":{"name":"ASIAN CARDIOVASCULAR & THORACIC ANNALS","volume":" ","pages":"244-255"},"PeriodicalIF":0.7,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140307175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of nil per oral, total parenteral nutrition, milrinone and non-suction chest tube drainage-based management for chylothorax following pediatric cardiac surgery. 针对小儿心脏手术后的乳糜胸,采用零口服、全胃肠外营养、米力农和无抽吸胸管引流术的疗效。
IF 0.7 Q3 Medicine Pub Date : 2024-04-24 DOI: 10.1177/02184923241249198
M. R. Rahmath, A. Bhat, R. A. Lone, R. Kamal
OBJECTIVEA single centre experience with chylothorax in post cardiac surgical patients.METHODSRetrospective review.RESULTSChylothorax developed in 55 out of 873 operated patients (6.3%). Median age of the chylothorax cohort was 95 days (range 1-995). Neonates constituted 36% and 49% were infants. Group-1(35 patients-treated during the years 2011-2015) included those who were managed with low fat diet initially with other standard measures including steroid, octreotide, pleurodesis, lymphangiogram or thoracic duct ligation whenever required.Group-2 (20 patients, treated between year 2016-2018) were managed with nil per oral, total parenteral nutrition, extended use of milrinone and no use of chest tube suction with other above standard measures when required.Group-1 and group-2 were comparable in terms of their age and weight (p > 0.05).We observed lower volume of chest drainage, shorter intubation time, length of intensive care stay and hospital stay in group-2 compared to group-1 though they were statistically not significant (p > 0.05). Occurrence of massive chylothorax (>20 ml/kg/day) in group-1 was significantly higher [18 patients (51%) in group-1 vs 4 patients in group-2 (20%) (Chi-square 5.25, p = 0.02)]. In hospital mortality in group-1 was higher compared to group-2 (5/35 = 14.5% vs 1/20 = 5%), however, it was statistically not significant [risk ratio 2.86; 95% CI 0.36, 22.77; p = 0.59)]. Acute kidney injury was observed in about 25% of patients who had chylothorax. A higher mortality was observed in patients with chylothorax who had acute kidney injury [5/14 (35%)] compared to those who did not have acute kidney injury [1/41 (2.4%)] (Chi-square 11.89, p = 0.001)].SUMMARYIn a heterogenous cohort of post-cardiac surgical patients who developed chylothorax, our suggested new regime (nil per oral, parenteral nutrition, extended use of milrinone and no suction applied to the chest drains) contributed to reduce the frequency of massive chylothorax occurrence significantly.
结果 873 例手术患者中有 55 例(6.3%)出现了乳糜胸。乳糜胸患者的中位年龄为 95 天(1-995 天不等)。新生儿占 36%,婴儿占 49%。第1组(35名患者,治疗时间为2011-2015年)包括最初采用低脂饮食并在必要时采取其他标准措施(包括类固醇、奥曲肽、胸膜穿刺术、淋巴管造影或胸导管结扎术)的患者。第2组(20名患者,治疗时间为2016-2018年)在必要时采用零口服、全胃肠外营养、延长米力农的使用时间、不使用胸管抽吸术以及其他上述标准措施。我们观察到,与第一组相比,第二组的胸腔引流量更少、插管时间更短、重症监护时间更长、住院时间更短,但这些数据在统计学上并不显著(P>0.05)。第一组出现大量乳糜胸(>20 毫升/千克/天)的比例明显更高[第一组有 18 名患者(51%),第二组有 4 名患者(20%)(Chi-square 5.25,P = 0.02)]。与第二组相比,第一组的住院死亡率更高(5/35 = 14.5% vs 1/20 = 5%),但在统计学上并不显著[风险比 2.86; 95% CI 0.36, 22.77; p = 0.59]]。约 25% 的乳糜胸患者出现急性肾损伤。与未出现急性肾损伤的患者[1/41 (2.4%)]相比,出现急性肾损伤的乳糜胸患者死亡率更高[5/14 (35%)](Chi-square 11.89, p = 0.001)]。总结:在一组心脏手术后出现乳糜胸的不同类型患者中,我们建议的新方案(无口服肠外营养、延长米力农的使用时间以及不对胸腔引流管进行抽吸)有助于显著降低大面积乳糜胸的发生率。
{"title":"Efficacy of nil per oral, total parenteral nutrition, milrinone and non-suction chest tube drainage-based management for chylothorax following pediatric cardiac surgery.","authors":"M. R. Rahmath, A. Bhat, R. A. Lone, R. Kamal","doi":"10.1177/02184923241249198","DOIUrl":"https://doi.org/10.1177/02184923241249198","url":null,"abstract":"OBJECTIVE\u0000A single centre experience with chylothorax in post cardiac surgical patients.\u0000\u0000\u0000METHODS\u0000Retrospective review.\u0000\u0000\u0000RESULTS\u0000Chylothorax developed in 55 out of 873 operated patients (6.3%). Median age of the chylothorax cohort was 95 days (range 1-995). Neonates constituted 36% and 49% were infants. Group-1(35 patients-treated during the years 2011-2015) included those who were managed with low fat diet initially with other standard measures including steroid, octreotide, pleurodesis, lymphangiogram or thoracic duct ligation whenever required.Group-2 (20 patients, treated between year 2016-2018) were managed with nil per oral, total parenteral nutrition, extended use of milrinone and no use of chest tube suction with other above standard measures when required.Group-1 and group-2 were comparable in terms of their age and weight (p > 0.05).We observed lower volume of chest drainage, shorter intubation time, length of intensive care stay and hospital stay in group-2 compared to group-1 though they were statistically not significant (p > 0.05). Occurrence of massive chylothorax (>20 ml/kg/day) in group-1 was significantly higher [18 patients (51%) in group-1 vs 4 patients in group-2 (20%) (Chi-square 5.25, p = 0.02)]. In hospital mortality in group-1 was higher compared to group-2 (5/35 = 14.5% vs 1/20 = 5%), however, it was statistically not significant [risk ratio 2.86; 95% CI 0.36, 22.77; p = 0.59)]. Acute kidney injury was observed in about 25% of patients who had chylothorax. A higher mortality was observed in patients with chylothorax who had acute kidney injury [5/14 (35%)] compared to those who did not have acute kidney injury [1/41 (2.4%)] (Chi-square 11.89, p = 0.001)].\u0000\u0000\u0000SUMMARY\u0000In a heterogenous cohort of post-cardiac surgical patients who developed chylothorax, our suggested new regime (nil per oral, parenteral nutrition, extended use of milrinone and no suction applied to the chest drains) contributed to reduce the frequency of massive chylothorax occurrence significantly.","PeriodicalId":35950,"journal":{"name":"ASIAN CARDIOVASCULAR & THORACIC ANNALS","volume":"66 20","pages":"2184923241249198"},"PeriodicalIF":0.7,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140663814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antiphospholipid antibody syndrome complicating infective endocarditis - case report. 感染性心内膜炎并发抗磷脂抗体综合征--病例报告。
IF 0.7 Q3 Medicine Pub Date : 2024-04-18 DOI: 10.1177/02184923241242874
Riju Nair, Shiv Nair, Mary Smitha, U. Dipin
A 37-year-old lady with infective endocarditis of the mitral valve presented in congestive cardiac failure. However, the clinical scenario became complicated when she was also found to have antiphospholipid antibody syndrome. Meticulous optimization and timely surgical intervention by a multidisciplinary team helped mitigate this not so common situation and lead to successful outcome.
一位患有二尖瓣感染性心内膜炎的 37 岁女士出现了充血性心力衰竭。然而,当她被发现患有抗磷脂抗体综合征时,临床情况变得复杂起来。多学科团队的精心优化和及时手术干预帮助缓解了这一并不常见的情况,并取得了成功。
{"title":"Antiphospholipid antibody syndrome complicating infective endocarditis - case report.","authors":"Riju Nair, Shiv Nair, Mary Smitha, U. Dipin","doi":"10.1177/02184923241242874","DOIUrl":"https://doi.org/10.1177/02184923241242874","url":null,"abstract":"A 37-year-old lady with infective endocarditis of the mitral valve presented in congestive cardiac failure. However, the clinical scenario became complicated when she was also found to have antiphospholipid antibody syndrome. Meticulous optimization and timely surgical intervention by a multidisciplinary team helped mitigate this not so common situation and lead to successful outcome.","PeriodicalId":35950,"journal":{"name":"ASIAN CARDIOVASCULAR & THORACIC ANNALS","volume":" 44","pages":"2184923241242874"},"PeriodicalIF":0.7,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140688199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incidence of venous thromboembolism after cardiovascular surgery. 心血管手术后静脉血栓栓塞的发生率。
IF 0.7 Q3 Medicine Pub Date : 2024-04-13 DOI: 10.1177/02184923241247112
Masato Saitoh, Takemi Kudo, Takao Watanabe
BACKGROUNDAmong venous thromboembolism, pulmonary thromboembolism (PTE) is one of the most serious postoperative complications. Deep venous thrombosis (DVT) is the main cause. Considering the unknown prevalence of DVT and PTE in the postoperative period of cardiovascular surgery in Japan, we investigated the incidence in consecutive patients who underwent cardiovascular surgery.METHODSA total of 225 patients who underwent cardiovascular surgery at four hospitals consented to participate in the study. We assessed DVT using lower extremity venous ultrasound preoperatively and postoperatively. Seven patients with preexisting DVT were excluded. Postoperative antithrombotic therapy was administered at the discretion of the attending physician at each institution. The postoperative intermittent pneumatic compression therapy followed the standard prophylaxis protocol at each institution. Patients were grouped into DVT and non-DVT cohorts for comparison. Continuous variables were expressed as means ± standard deviations and compared by the t-test.RESULTSThe analysis of lower extremity venous ultrasound images indicated that DVT developed in 16 of the 218 study patients (DVT, 7.3%). No patient had PTE. Procedure-related data revealed significantly higher total blood transfusion (DVT group: 61.2 ± 49.9 IU vs. non-DVT group: 27.7 ± 30.2 IU: p = 0.018, effect size = 1.048) in the DVT group. The multivariate logistic regression predictor of DVT based on preoperative, intraoperative, and postoperative factors was blood transfusion (p = 0.005, 95% confidence interval 1.010-1.059, odds ratio 1.034).CONCLUSIONSThe incidence of postoperatively developed DVT was 7.3% in this study.
背景在静脉血栓栓塞症中,肺血栓栓塞症(PTE)是最严重的术后并发症之一。深静脉血栓形成(DVT)是主要原因。考虑到日本心血管手术术后深静脉血栓和肺血栓栓塞症的发病率尚不清楚,我们对连续接受心血管手术的患者的发病率进行了调查。我们在术前和术后使用下肢静脉超声波对深静脉血栓进行了评估。排除了 7 名已有深静脉血栓的患者。术后抗血栓治疗由各家医院的主治医生决定。术后间歇性气动加压疗法遵循各医疗机构的标准预防方案。患者分为深静脉血栓组和非深静脉血栓组进行比较。结果下肢静脉超声图像分析表明,218 名研究患者中有 16 人发生了深静脉血栓(深静脉血栓,7.3%)。没有患者出现 PTE。手术相关数据显示,输血总量明显增加(深静脉血栓组:61.2 ± 49.9 I/L):DVT组:61.2 ± 49.9 IU vs. 非DVT组:27.7 ± 30.2 IU:P = 0.018,效应大小 = 1.048)。基于术前、术中和术后因素的多变量逻辑回归预测因子为输血(p = 0.005,95% 置信区间 1.010-1.059,几率比 1.034)。
{"title":"Incidence of venous thromboembolism after cardiovascular surgery.","authors":"Masato Saitoh, Takemi Kudo, Takao Watanabe","doi":"10.1177/02184923241247112","DOIUrl":"https://doi.org/10.1177/02184923241247112","url":null,"abstract":"BACKGROUND\u0000Among venous thromboembolism, pulmonary thromboembolism (PTE) is one of the most serious postoperative complications. Deep venous thrombosis (DVT) is the main cause. Considering the unknown prevalence of DVT and PTE in the postoperative period of cardiovascular surgery in Japan, we investigated the incidence in consecutive patients who underwent cardiovascular surgery.\u0000\u0000\u0000METHODS\u0000A total of 225 patients who underwent cardiovascular surgery at four hospitals consented to participate in the study. We assessed DVT using lower extremity venous ultrasound preoperatively and postoperatively. Seven patients with preexisting DVT were excluded. Postoperative antithrombotic therapy was administered at the discretion of the attending physician at each institution. The postoperative intermittent pneumatic compression therapy followed the standard prophylaxis protocol at each institution. Patients were grouped into DVT and non-DVT cohorts for comparison. Continuous variables were expressed as means ± standard deviations and compared by the t-test.\u0000\u0000\u0000RESULTS\u0000The analysis of lower extremity venous ultrasound images indicated that DVT developed in 16 of the 218 study patients (DVT, 7.3%). No patient had PTE. Procedure-related data revealed significantly higher total blood transfusion (DVT group: 61.2 ± 49.9 IU vs. non-DVT group: 27.7 ± 30.2 IU: p = 0.018, effect size = 1.048) in the DVT group. The multivariate logistic regression predictor of DVT based on preoperative, intraoperative, and postoperative factors was blood transfusion (p = 0.005, 95% confidence interval 1.010-1.059, odds ratio 1.034).\u0000\u0000\u0000CONCLUSIONS\u0000The incidence of postoperatively developed DVT was 7.3% in this study.","PeriodicalId":35950,"journal":{"name":"ASIAN CARDIOVASCULAR & THORACIC ANNALS","volume":"31 121","pages":"2184923241247112"},"PeriodicalIF":0.7,"publicationDate":"2024-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140708300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Giant mediastinal thymolipoma - complete resection through a sternotomy. 巨大纵隔胸腺脂肪瘤--经胸骨切口完全切除。
IF 0.7 Q3 Medicine Pub Date : 2024-03-01 Epub Date: 2024-01-09 DOI: 10.1177/02184923231225792
Santhosh Regini Benjamin, Angel Miraclin T, Aamir Mohammad, Korah Thomas Kuruvila
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引用次数: 0
Efficacy and safety of transcatheter arterial embolization of omental artery aneurysm: A single-center experience. 经导管动脉栓塞治疗网膜动脉瘤的有效性和安全性:单中心经验。
IF 0.7 Q3 Medicine Pub Date : 2024-03-01 Epub Date: 2024-02-01 DOI: 10.1177/02184923241229117
Yosuke Nozawa, Shigeshi Ono, Yasuaki Hasegawa, Takao Igarashi, Shun Kusada, Kyoko Arahata, Kenji Nakamura, Koshi Ikeda, Hirotoshi Hasegawa

Background: Omental artery aneurysm (OAA) is an extremely rare visceral artery aneurysm. Ruptured OAAs are associated with a high mortality rate. Transcatheter arterial embolization (TAE) has been used to treat OAA in recent years. However, the risk of omental ischemia due to TAE remains unclear. Therefore, this study aimed to investigate the efficacy and safety of TAE of OAA as a first-line treatment.

Methods: Fifteen patients with true aneurysms or pseudoaneurysms who underwent OAA-TAE between 1 April 2010 and 31 December 2022 were included in this study. The technical and clinical outcomes, the incidence of omental infarction after TAE as a major complication, OAA-TAE techniques, radiological findings on computed tomography angiography and angiogram, and patient characteristics were evaluated.

Results: Fifteen patients (nine men, six women; age, 69.8 ± 18.59 years) underwent TAE of OAAs (mean aneurysm size of 9.30 ± 6.10 mm) located in the right gastroepiploic (n = 9), left gastroepiploic (n = 1), and epiploic (n = 5) arteries. All patients with ruptured (n = 6) and unruptured (n = 9) OAA successfully underwent TAEs using coils, n-butyl-2-cyanoacrylate, or gelatin sponges. Hepatic artery thrombosis and coil migration were observed during the procedure; however, these adverse events were manageable. Transfusion of red blood cell units (4.66 ± 1.63 units) was required only in cases with ruptured OAAs after TAE. Additional surgery or TAE due to rupture or rerupture of OAA and omental infarction was not required during the postoperative and follow-up periods.

Conclusion: The OAA-TAE can effectively treat ruptured and unruptured OAAs, and the risk of omental infarction after OAA-TAE may not be high.

背景:网膜动脉瘤(OAA)是一种极其罕见的内脏动脉瘤。网膜动脉瘤破裂后死亡率很高。近年来,经导管动脉栓塞术(TAE)已被用于治疗网膜动脉瘤。然而,TAE导致网膜缺血的风险仍不明确。因此,本研究旨在探讨 TAE 作为一线治疗 OAA 的有效性和安全性:本研究纳入了 15 例在 2010 年 4 月 1 日至 2022 年 12 月 31 日期间接受 OAA-TAE 的真性动脉瘤或假性动脉瘤患者。对技术和临床结果、TAE术后作为主要并发症的网膜梗死发生率、OAA-TAE技术、计算机断层扫描血管造影和血管造影的放射学结果以及患者特征进行了评估:15名患者(9名男性,6名女性;年龄69.8±18.59岁)接受了位于右胃网膜动脉(9人)、左胃网膜动脉(1人)和上网膜动脉(5人)的OAA(平均动脉瘤大小为9.30±6.10毫米)TAE手术。所有破裂(6 例)和未破裂(9 例)的 OAA 患者都成功接受了使用线圈、2-氰基丙烯酸正丁酯或明胶海绵的 TAE。手术过程中观察到肝动脉血栓形成和线圈移位,但这些不良反应都是可以控制的。只有在 TAE 后出现 OAA 破裂的病例才需要输注红细胞单位(4.66 ± 1.63 单位)。在术后和随访期间,没有人因OAA破裂或再破裂以及网膜梗塞而需要再次手术或TAE:结论:OAA-TAE 可有效治疗破裂和未破裂的 OAA,OAA-TAE 后发生网膜梗死的风险可能并不高。
{"title":"Efficacy and safety of transcatheter arterial embolization of omental artery aneurysm: A single-center experience.","authors":"Yosuke Nozawa, Shigeshi Ono, Yasuaki Hasegawa, Takao Igarashi, Shun Kusada, Kyoko Arahata, Kenji Nakamura, Koshi Ikeda, Hirotoshi Hasegawa","doi":"10.1177/02184923241229117","DOIUrl":"10.1177/02184923241229117","url":null,"abstract":"<p><strong>Background: </strong>Omental artery aneurysm (OAA) is an extremely rare visceral artery aneurysm. Ruptured OAAs are associated with a high mortality rate. Transcatheter arterial embolization (TAE) has been used to treat OAA in recent years. However, the risk of omental ischemia due to TAE remains unclear. Therefore, this study aimed to investigate the efficacy and safety of TAE of OAA as a first-line treatment.</p><p><strong>Methods: </strong>Fifteen patients with true aneurysms or pseudoaneurysms who underwent OAA-TAE between 1 April 2010 and 31 December 2022 were included in this study. The technical and clinical outcomes, the incidence of omental infarction after TAE as a major complication, OAA-TAE techniques, radiological findings on computed tomography angiography and angiogram, and patient characteristics were evaluated.</p><p><strong>Results: </strong>Fifteen patients (nine men, six women; age, 69.8 ± 18.59 years) underwent TAE of OAAs (mean aneurysm size of 9.30 ± 6.10 mm) located in the right gastroepiploic (<i>n</i> = 9), left gastroepiploic (<i>n</i> = 1), and epiploic (<i>n</i> = 5) arteries. All patients with ruptured (<i>n</i> = 6) and unruptured (<i>n</i> = 9) OAA successfully underwent TAEs using coils, <i>n</i>-butyl-2-cyanoacrylate, or gelatin sponges. Hepatic artery thrombosis and coil migration were observed during the procedure; however, these adverse events were manageable. Transfusion of red blood cell units (4.66 ± 1.63 units) was required only in cases with ruptured OAAs after TAE. Additional surgery or TAE due to rupture or rerupture of OAA and omental infarction was not required during the postoperative and follow-up periods.</p><p><strong>Conclusion: </strong>The OAA-TAE can effectively treat ruptured and unruptured OAAs, and the risk of omental infarction after OAA-TAE may not be high.</p>","PeriodicalId":35950,"journal":{"name":"ASIAN CARDIOVASCULAR & THORACIC ANNALS","volume":" ","pages":"107-115"},"PeriodicalIF":0.7,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139673093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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ASIAN CARDIOVASCULAR & THORACIC ANNALS
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