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Real-World Views of Patching Differ to Health Professionals': An Online Survey of Professionals, Patients, Teachers, Parents and Carers. 现实世界对打补丁的看法与卫生专业人员不同:一项对专业人员、患者、教师、家长和护理人员的在线调查。
Q3 Medicine Pub Date : 2025-04-29 eCollection Date: 2025-01-01 DOI: 10.22599/bioj.404
Daniel Osborne, Maddison McGowen, Jeremy Bradshaw, Helen Ellis, Megan Evans, James Stallwood, Joerg Fliege, Jay Self

Background: Patching therapy is the most common treatment for amblyopia (lazy eye) and is unsuccessful for approximately 40% of patients, leaving them with life-long unilateral visual impairment and increased risk of bilateral visual impairment later in life. Poor adherence to patching therapy is a major contributing factor in treatment failure yet we lack real-world understanding as to why this is a problem outside of controlled research studies.

Methods: In collaboration with patient contributors, we developed an online survey for past patients, parents/carers of children with amblyopia, health professionals, and schoolteachers. The survey included questions about when and where is best for children to wear the patch, the design of the patch, and facilitators and barriers to patching therapy.

Results: We received 631 responses to the survey (259 health professionals, 213 parents/carers, 110 people who patched as a child, 7 teachers, and 42 people matched to multiple categories). Healthcare professionals thought weekday (54.4% versus 14.3% preferring weekend and 31.3% no difference) and school (54.4% versus 21.6% preferred home and 23.9% no difference) patching was more successful. Past patients (52.4%) favoured 'force' as a technique to encourage patching; more than both health professionals (7.7%) and parents or carers (19.7%). Patients rated 'people making fun' of them as an important barrier to patching.

Conclusions: We describe surprising differences in stakeholders' responses to the survey questions about barriers to successful patching treatment. We suggest these differences are used as a guide for further work to explore stakeholder's social experience of patching.

背景:补片治疗是治疗弱视最常见的方法,约40%的患者不成功,使他们终生单侧视力受损,并增加了以后生活中双侧视力受损的风险。治疗失败的一个主要原因是对修补疗法的依从性差,但我们缺乏现实世界的理解,为什么这是一个受控研究之外的问题。方法:我们与患者合作,对过去的患者、弱视儿童的父母/照顾者、卫生专业人员和学校教师进行了在线调查。调查的问题包括:何时何地最适合儿童佩戴贴片,贴片的设计,以及贴片治疗的促进因素和障碍。结果:我们收到了631份调查回复(259名卫生专业人员,213名家长/照顾者,110名儿童,7名教师,42名多类别匹配者)。医疗保健专业人员认为工作日(54.4%对14.3%,31.3%没有差异)和学校(54.4%对21.6%,23.9%没有差异)修补更成功。既往患者(52.4%)倾向于“用力”作为鼓励补片的技术;超过卫生专业人员(7.7%)和父母或照顾者(19.7%)。患者认为,“有人在取笑”他们,这是他们修复补丁的一个重要障碍。结论:我们描述了利益相关者对成功修补治疗障碍的调查问题的反应的惊人差异。我们建议将这些差异作为进一步工作的指南,以探索利益相关者的社会补丁体验。
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引用次数: 0
Children with Additional Support Needs Risk Missing Out on Effective Vision Screening: Audit and Survey Considering Attendance Rates and Parent Reported Barriers to Service Access, including Recommendations for Improvement. 有额外支持需求的儿童有可能错过有效的视力筛查:考虑出勤率和家长报告的服务获取障碍的审计和调查,包括改进建议。
Q3 Medicine Pub Date : 2025-04-03 eCollection Date: 2025-01-01 DOI: 10.22599/bioj.451
Cirta Tooth, Julius Rogowski

Objective: Vision screening programs in children aged 4-5 years aim to address visual issues before they start school, supporting children's educational, developmental, emotional, and social well-being. This study evaluates attendance rates and barriers to attendance for children requiring follow-up in an urban hospital eye service after their initial screening visit.

Methods and analysis: Retrospective data on attendance, visual acuity, refractive errors, and presence of additional support needs (ASN) were collected from the National Database for preschool screening and the hospital electronic record system. Caregivers of children with missed appointments were invited for a telephone survey.

Results: First-time hospital attendance rate was 61%. Children with ASN were 1.8× more likely to miss two hospital appointments and had more incomplete tests compared to children without ASN. In children receiving a spectacle prescription, vision improved by 0.07 LogMAR in the better eye and 0.16 LogMAR in the worse eye. Barriers for attendance included being unaware of the appointment, ASN, hospital environment, scheduling and transport issues. Parents recommended information with the appointment letter in an accessible language for the child and caregiver, an appointment reminder text message and options for vision tests in the community or at school.

Conclusion: Whilst the initial uptake of vision screening is high, there is a significant proportion of children with incomplete screening tests or missed follow-up appointments. Greater attention should be placed on improving accessibility of the service for children with ASN, as they may be at greater risk of missing out on appropriate eye care.

目的:4-5岁儿童的视力筛查项目旨在在他们开始上学之前解决视力问题,支持儿童的教育,发展,情感和社会福祉。本研究评估了在城市医院眼科服务进行首次筛查后需要随访的儿童的出勤率和出勤率障碍。方法和分析:从国家学前筛查数据库和医院电子记录系统中收集出勤、视力、屈光不正和存在额外支持需求(ASN)的回顾性数据。失约儿童的看护人被邀请进行电话调查。结果:首次住院率为61%。与没有ASN的儿童相比,有ASN的儿童错过两次医院预约的可能性高1.8倍,并且有更多不完整的检查。在接受眼镜处方的儿童中,较好眼的视力提高了0.07 LogMAR,较差眼的视力提高了0.16 LogMAR。就诊的障碍包括不知道预约、ASN、医院环境、日程安排和交通问题。家长们推荐的信息包括:用儿童和看护人可以理解的语言写的预约信、预约提醒短信以及在社区或学校进行视力测试的选项。结论:虽然最初接受视力筛查的儿童比例很高,但筛查试验不完整或错过随访预约的儿童比例很高。应更加重视改善ASN儿童的服务可及性,因为他们可能有更大的风险错过适当的眼科护理。
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引用次数: 0
Bullying and Incivility Experiences of Undergraduate Orthoptic Students on Clinical Placement. 骨科实习大学生恃强凌弱和不文明行为的经历。
Q3 Medicine Pub Date : 2025-03-21 eCollection Date: 2025-01-01 DOI: 10.22599/bioj.368
Konstandina Koklanis, Meri Vukicevic, Andrea Simpson, Bojana Šarkić

Introduction: Clinical placements in allied health are crucial for students to develop skills in real-world settings. However, these environments can expose students to incidents of incivility, bullying, or harassment. Whilst much research has explored bullying in medicine and nursing, little is known about the rate or effect of bullying in smaller allied health professions. This study aimed to investigate the frequency of bullying incidents among final year orthoptic students and assess the consequential effects of this experience.

Methods: In this cross-sectional study, final year orthoptic students and graduates who had completed placements in the preceding year were invited to complete an online survey. The survey instrument was adapted from the Clinical Workplace Learning Negative Acts Questionnaire-Revised. Information on demographics, placement attributes, bullying experiences, and their effects was gathered. The data were analysed using descriptive statistics.

Results: A total of 20 individuals responded to the survey; 12 (60%) final year students and 8 (40%) graduates. Almost all participants (95%) reported experiencing at least one negative act whilst on placement, with 10 (50%) indicating they experienced bullying. Of these 10, all reported feeling humiliated by the incidents, and 90% reported a loss of confidence. Almost all students (90%) did not report the behaviour when it happened, with most students also being unaware of bullying and harassment policies of the university or health facility.

Conclusion: Bullying and incivility pose challenges for orthoptic students during placements. This study highlights gaps in policy implementation and underscores the need for effective measures to address this issue.

简介:临床实习在联合健康是至关重要的学生发展技能,在现实世界的设置。然而,这些环境可能会使学生暴露在不文明、欺凌或骚扰的事件中。虽然有很多研究探讨了医学和护理中的欺凌行为,但对较小的联合卫生专业中欺凌行为的比率或影响知之甚少。摘要本研究旨在调查正视系毕业班学生受霸凌事件的频率,并评估霸凌事件对学生的影响。方法:在横断面研究中,邀请前一年完成实习的最后一届正视镜学生和毕业生完成在线调查。调查工具改编自《临床工作场所学习消极行为问卷-修订版》。收集了有关人口统计、安置属性、欺凌经历及其影响的信息。使用描述性统计对数据进行分析。结果:共有20人参与了调查;12名(60%)大四学生和8名(40%)毕业生。几乎所有参与者(95%)报告说,在安置期间至少经历过一次负面行为,10人(50%)表示他们经历过欺凌。在这10人中,所有人都表示自己受到了这些事件的羞辱,90%的人表示失去了信心。几乎所有学生(90%)在发生这种行为时都没有报告,大多数学生也不知道大学或卫生机构的欺凌和骚扰政策。结论:在实习期间,欺凌和不文明行为给正视学生带来了挑战。这项研究突出了政策执行方面的差距,并强调需要采取有效措施来解决这一问题。
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引用次数: 0
The Role of Orthoptists in Refraction. 验光师在折射中的作用。
Q3 Medicine Pub Date : 2025-02-14 eCollection Date: 2025-01-01 DOI: 10.22599/bioj.384
Miriam L Conway, Rakhee Shah, Elizabeth Chapman, Bruce J W Evans

Purpose: In 2022, the General Optical Council initiated a call for evidence concerning the Opticians Act. This consultation aimed to gather input and evidence relevant to potential modifications to the Opticians Act. One piece of research that was commissioned aimed to investigate the role of orthoptists in refraction.

Method: We invited a range of eye care practitioners to participate in an online virtual focus group. Focus group discussions were audio-recorded, transcribed, and thematically analysed.

Results: Two focus group discussions involving sixteen eye care professionals were completed. Findings confirm some orthoptists are already performing refraction tasks within the hospital eye service, primarily with young children using cycloplegic retinoscopy. Participants indicated that, at present, orthoptists refract on behalf of ophthalmologists who issue spectacle prescriptions based on the findings of the orthoptist's refraction. Potential benefits of orthoptists undertaking refraction responsibilities were discussed including the ability to conduct retinoscopy in hospital paediatric clinics where services are in high demand and there is often a shortage of refraction appointments. This shift could lead to decreased NHS waiting times, fewer patient appointments, improved clinical decision-making, and facilitate the assessment of accommodative dysfunction. Overall, the group were positive towards orthoptists conducting refractions and issuing optical prescriptions but with specific conditions: limited to hospital settings, necessitating adequate postgraduate training, supervision by a hospital eye service consultant, and regular ocular health assessments.

Conclusion: This study assessed the involvement of orthoptists in present and prospective refraction services, including their potential to legally issue optical prescriptions. The research outlined both the potential benefits and mitigating strategies to address concerns if orthoptists could issue optical prescriptions.

目的:在2022年,总光学委员会发起了一项关于光学法案的证据呼吁。本次咨询旨在收集与《眼镜商法》的潜在修改相关的输入和证据。委托进行的一项研究旨在调查验光师在折射中的作用。方法:我们邀请了一系列眼保健从业人员参加一个在线虚拟焦点小组。对焦点小组的讨论进行了录音、转录和专题分析。结果:完成了两次焦点小组讨论,涉及16名眼科专业人员。研究结果证实,一些眼科医生已经在医院眼科服务中执行屈光检查任务,主要是对使用睫状体瘫痪的幼儿进行视网膜镜检查。与会者指出,目前,视光师代表眼科医生验光,后者根据视光师的验光结果开具眼镜处方。讨论了眼科医生承担屈光检查责任的潜在好处,包括在医院儿科诊所进行视网膜镜检查的能力,那里的服务需求很高,而且经常缺乏屈光检查预约。这种转变可以减少NHS等待时间,减少患者预约,改善临床决策,并促进调节功能障碍的评估。总体而言,该小组对验光师进行屈光检查和开具眼科处方持积极态度,但有特定条件:仅限于医院环境,需要适当的研究生培训,由医院眼科服务顾问监督,并定期进行眼部健康评估。结论:本研究评估了验光师在当前和未来屈光服务中的参与情况,包括他们合法开具验光处方的潜力。该研究概述了潜在的好处和缓解策略,以解决人们对眼科医生是否可以开眼科处方的担忧。
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引用次数: 0
Response to: Arblaster G, Buckley D, Barnes S, Davis H Strabismus Surgery for Psychosocial Reasons - A Literature Review. British and Irish Orthoptic Journal 2024;20:107-132. 回应:Arblaster G, Buckley D, Barnes S, Davis H .斜视手术的社会心理原因-文献综述。英国和爱尔兰Orthoptic杂志2024;20:107-132。
Q3 Medicine Pub Date : 2025-01-24 eCollection Date: 2025-01-01 DOI: 10.22599/bioj.448
Garth Johnston

Language is important. Words we use can be much more descriptive. We propose using the prefix reconstruction when describing strabismus surgery. This word emphaises that extra ocualr muscle surgery is much more that cosmetic, it is always functional even when restoring facial aesthetics that improve patients confidence and perception fo themselves to others.

语言很重要。我们使用的词语可以更具描述性。我们建议在描述斜视手术时使用前缀重建。这个词强调额外的眼肌手术不仅仅是美容,它总是功能性的,即使是在恢复面部美学的时候,也能提高病人的信心和对他人的看法。
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引用次数: 0
The Psychological Impact of Amblyopia Treatment: A Systematic Literature Review. 弱视治疗的心理影响:系统文献综述。
Q3 Medicine Pub Date : 2025-01-16 eCollection Date: 2025-01-01 DOI: 10.22599/bioj.426
Louisa Haine, Isaac Taylor, Megan Vaughan

Aim: The aim of this literature review was to determine if a consensus could be reached on whether amblyopia treatment causes distress to patients and/or their guardians, and if so, establish the impact of this reported psychological distress upon paediatric patients and/or their parents/guardians.

Methods: A systematic review of the literature was conducted of all publications written in English. Search terms included both MeSH terms and alternatives related to amblyopia and psychological distress. Evidence quality was assessed using an adapted Newcastle-Ottawa Score (NOS) and evaluation of the literature was used to form a narrative synthesis of the findings.

Results: Initial searches yielded 7,838 titles in total, with 25 peer reviewed papers published between 1999 and 2021 meeting the study inclusion criteria. Factors such as the presence of strabismus, moderate and severe amblyopic density, occlusive patch treatment and patching during school age increase the likelihood of experiencing distress as a result of amblyopia treatment.

Conclusions: Both parents/guardians and patients can experience psychological distress as a result of undertaking amblyopia treatment. School-aged children and those receiving occlusion therapy in the form of patching report higher distress than infants and young-children, and those receiving atropine occlusion therapy or refractive correction only. Further study measuring the physiological markers of distress such as Cortisol and BDNF, is recommended.

目的:本文献综述的目的是确定是否可以就弱视治疗是否会对患者和/或其监护人造成困扰达成共识,如果是这样,则确定所报道的心理困扰对儿科患者和/或其父母/监护人的影响。方法:对所有英文出版物进行系统的文献综述。搜索词包括MeSH术语和与弱视和心理困扰相关的替代词。采用纽卡斯尔-渥太华评分(NOS)对证据质量进行评估,并对文献进行评估,形成对研究结果的叙述性综合。结果:初步检索共产生7838篇论文,其中25篇发表于1999年至2021年间的同行评议论文符合研究纳入标准。存在斜视、中度和重度弱视密度、闭塞贴片治疗和学龄贴片等因素增加了因弱视治疗而经历痛苦的可能性。结论:接受弱视治疗后,家长/监护人和患者均会产生心理困扰。学龄儿童和接受贴片形式的闭塞治疗的儿童比婴幼儿和仅接受阿托品闭塞治疗或屈光矫正的儿童报告更高的痛苦。建议进一步研究测量诸如皮质醇和BDNF等痛苦的生理标记。
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引用次数: 0
Occlusion Outcomes in Unilateral Amblyopia Types: A Longitudinal and Interventional Study in Children from the Marrakech-Safi Region. 单侧弱视类型的闭塞结局:马拉喀什-萨菲地区儿童的纵向和介入研究。
Q3 Medicine Pub Date : 2024-12-27 eCollection Date: 2024-01-01 DOI: 10.22599/bioj.382
Mustapha Jaouhari, Chaimae El Harrak, Farida Bentayeb, Youssef El Merabet

Objective: To investigate if the type of unilateral amblyopia can impact the improvement of visual acuity in amblyopic eyes during a longitudinal interventional study involving standard occlusion therapy in children.

Methods: A longitudinal and interventional study of 91 children, aged 3-9 years (6.12 ± 1.879) with amblyopia was undertaken. Amblyopia was unilateral and caused by either strabismus, anisometropia, or both. Amblyopia was divided into three levels of severity mild, moderate, and severe. Children underwent amblyopia treatment with standard occlusion therapy and were followed monthly, for eight visits.

Results: A significant improvement in visual acuity was observed in all assessment visits across the three types of amblyopia, with a mean improvement of (0.30 ± 0.184) LogMAR. Specifically, anisometropic amblyopia with (0.28 ± 0.18) LogMAR, strabismic amblyopia (0.31 ± 0.18) LogMAR, and mixed amblyopia (0.31 ± 0.18) LogMAR. No significant differences were found between the improvement in visual acuity during the eight control visits and the types of amblyopia (r = 0.174, p = 0.182). However, a significant correlation was observed within all groups in the mean improvement in visual acuity and the severity level (r = 0.712, p = 0.034).

Conclusion: Amblyopia types do not appear to significantly affect the improvement in visual acuity; however, the initial severity of amblyopia may be a key factor influencing the degree of visual recovery achieved with occlusion therapy.

目的:通过一项儿童单侧弱视的纵向介入研究,探讨单侧弱视的类型是否会影响弱视患者视力的改善。方法:对91例3 ~ 9岁(6.12±1.879)弱视儿童进行纵向和介入研究。弱视是单侧的,由斜视、参差或两者同时引起。弱视的严重程度分为轻度、中度和重度三个等级。儿童接受标准遮挡治疗弱视,每月随访8次。结果:三种类型弱视患者的视力在所有评估访问中均有显著改善,平均改善幅度为(0.30±0.184)LogMAR。其中,各向异性弱视(0.28±0.18)LogMAR,斜视(0.31±0.18)LogMAR,混合性弱视(0.31±0.18)LogMAR。8次对照访视期间视力改善程度与弱视类型无显著性差异(r = 0.174, p = 0.182)。然而,在所有组中,平均视力改善程度与严重程度之间存在显著相关性(r = 0.712, p = 0.034)。结论:弱视类型对视力的改善无明显影响;然而,弱视的初始严重程度可能是影响闭塞治疗视力恢复程度的关键因素。
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引用次数: 0
Idiopathic Intracranial Hypertension - How Can Orthoptists Help Improve Care? 特发性颅内高压-矫形师如何帮助改善护理?
Q3 Medicine Pub Date : 2024-12-06 eCollection Date: 2024-01-01 DOI: 10.22599/bioj.427
Daisy MacKeith

Care for people with idiopathic intracranial hypertension (IIH) needs improving and I think orthoptists are in a perfect position to help. The problems with IIH care are multi-fold:  People with fulminant IIH are still losing sight due to delayed diagnosis or mismanagement.People with IIH often have a poor quality of life due to disabling chronic headaches and poor mental health.There is a lack of access to evidence-based weight-loss interventions and support.Weight stigma in healthcare remains pervasive and damaging and disproportionately impacts women.Functional vision loss and headaches in IIH can complicate the interpretation of visual function which can have implications for management.There is a lack of evidence to support treatment options. Below I will describe the issues in more detail and outline the ways in which we as orthoptists can help this patient group.

特发性颅内高压(IIH)患者的护理需要改进,我认为矫形外科医生可以提供完美的帮助。IIH护理的问题是多方面的:暴发性IIH患者仍因诊断延误或管理不善而失明。IIH患者的生活质量往往较差,原因是慢性头痛致残性和精神健康状况不佳。缺乏以证据为基础的减肥干预和支持。医疗保健中的体重污名仍然普遍存在,具有破坏性,对妇女的影响不成比例。IIH的功能性视力丧失和头痛可使视觉功能的解释复杂化,这可能对治疗产生影响。目前缺乏支持治疗方案的证据。下面我将更详细地描述这些问题,并概述我们作为骨科医生可以帮助这一患者群体的方法。
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引用次数: 0
Enhancing Paediatric and Strabismus Ophthalmology Departments in Spain Through the Inclusion of Orthoptists: Insights from a Nationwide Survey. 通过纳入眼科医生加强西班牙儿科和斜视眼科:来自全国调查的见解。
Q3 Medicine Pub Date : 2024-12-03 eCollection Date: 2024-01-01 DOI: 10.22599/bioj.359
Ana María Cruz Lasso

Background and objectives: The absence of the orthoptic profession in Spain contrasts with its value and recognition in other countries. This study aimed to gauge Spanish ophthalmologists' interest in including and promoting orthoptists in paediatric and strabismus departments. Secondary objectives included assessing interest in requesting orthoptists, involvement in their training, and aligning their competencies with European standards.

Methodology: Participants were recruited via WhatsApp and flyers during the 30th SEEOP Congress in May 2023 and invited to review a report on orthoptists' significance followed by completing a 12-question online survey. Profile questions were asked via multiple-choice options. Opinions on integrating orthoptists to enhance care quality, training involvement, and alignment with European standards were rated using a Likert scale. Open-ended questions captured themes, and comments.

Results: Forty-two paediatric and strabismologists in Spain participated, mostly hospital-employed with advanced degrees, 90% supported integrating orthoptists into their teams, with 83% interested in having them in their workplace. Nearly 90% believed that collaboration between ophthalmologists and orthoptists would improve care quality and reduce waiting lists, and 83% supported promoting this within national medical organisations. Additionally, 90% advocated level 4 advanced European-standard training for orthoptists and 25% were neutral about participating in training orthoptists. Participants emphasised the importance of qualified orthoptists for treating eye movement abnormalities, distinguishing them from other eye healthcare professionals and advocating for collaboration rather than replacement.

Conclusions: This initial survey of paediatric ophthalmologists and strabismologists in Spain highlights support for orthoptists as allied health professionals, though garnering support for their training could be challenging. These conclusions should be considered in light of methodological, sample size, and resource limitations. The survey serves as a pilot for the future, suggesting improvements to explore the feasibility of introducing orthoptists in Spain.

背景和目的:西班牙缺乏正视镜专业,这与其他国家对其的重视和认可形成了鲜明对比。这项研究旨在衡量西班牙眼科医生在包括和促进眼科医生在儿科和斜视部门的兴趣。次要目标包括评估请求骨科医生的兴趣,参与他们的培训,并使他们的能力与欧洲标准保持一致。方法:在2023年5月举行的第30届SEEOP大会期间,通过WhatsApp和传单招募参与者,邀请他们回顾一份关于骨科医生重要性的报告,然后完成一份包含12个问题的在线调查。个人资料问题是通过多项选择选项提出的。使用李克特量表对整合骨科医生以提高护理质量、培训参与和与欧洲标准保持一致的意见进行评级。开放式问题抓住了主题和评论。结果:西班牙的42名儿科和斜视医生参与了这项研究,他们大多是拥有高等学位的医院员工,90%的人支持将骨科医生纳入他们的团队,83%的人有兴趣让他们在工作场所工作。近90%的人认为眼科医生和骨科医生之间的合作可以提高护理质量,减少等待名单,83%的人支持在国家医疗机构中推广这种合作。此外,90%的受访医师主张对骨科医师进行欧洲四级高级标准培训,25%的受访医师对参与骨科医师培训持中立态度。与会者强调合格的眼科医生对治疗眼动异常的重要性,将他们与其他眼科保健专业人员区分开来,并提倡合作而不是替代。结论:这项对西班牙儿科眼科医生和斜视医生的初步调查强调了对骨科医生作为联合卫生专业人员的支持,尽管获得对他们培训的支持可能具有挑战性。这些结论应考虑到方法、样本量和资源限制。该调查作为未来的试点,提出了改进建议,以探索在西班牙引入骨科医生的可行性。
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引用次数: 0
Case Series Review on Use of Topical Timolol in the Treatment of Superior Oblique Myokymia. 局部应用替马洛尔治疗上斜肌肌痛的病例回顾。
Q3 Medicine Pub Date : 2024-12-02 eCollection Date: 2024-01-01 DOI: 10.22599/bioj.376
Victoria Alexis Smerdon, Joanne Adeoye, Alison Rowlands

Introduction: The treatment options available for Superior Oblique Myokymia (SOM) previously included surgery and systemic drugs, with the addition of beta blockers from the early 1990's. This case review aims to examine the efficacy of topical timolol (0.5%) as a treatment for SOM in the short and long term.

Methods: This is a retrospective case series review on a group of patients identified with this condition who have been assessed and treated with topical timolol 0.5% (off-label), within the same district and general hospital over a period of four years.

Results: Six patients were identified from the case review. Five out of the six patients were treated with the use of off label timolol 0.5%. One patient declined treatment due to other systemic conditions and another later discontinued treatment due to change in cardiac status. Two of the patients required increased dosage from OD to BD to achieve success initially. All the patients treated were symptom free at eight weeks and remained symptom free at six months follow-up. None of the patients in the cohort reported significant side effects.

Conclusion: This case series highlights the efficacy of the use of off label timolol 0.5% for the management of SOM with an 80% success rate for those treated with the drug.

简介:上斜肌肌病(SOM)的治疗方案以前包括手术和全身药物,并从20世纪90年代初开始使用受体阻滞剂。本病例综述旨在研究局部使用0.5%噻莫洛尔(timolol)治疗SOM的短期和长期疗效。方法:这是一项回顾性的病例系列综述,对一组确诊为这种疾病的患者进行了评估,并在同一地区和综合医院接受了0.5%的局部替莫洛尔(标签外)治疗,为期四年。结果:从病例回顾中确定了6例患者。6例患者中有5例使用未标示的0.5%替洛尔治疗。一名患者因其他全身性疾病而拒绝治疗,另一名患者后来因心脏状态改变而停止治疗。两名患者最初需要增加剂量从OD到BD才能取得成功。所有接受治疗的患者在8周时均无症状,并在6个月的随访中保持无症状。该队列中没有患者报告有明显的副作用。结论:本病例系列强调了使用未经核准的0.5%替洛尔治疗SOM的有效性,使用该药物治疗的患者成功率为80%。
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引用次数: 0
期刊
British and Irish Orthoptic Journal
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