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The Impact of Visual Impairment on Completion of Cognitive Screening Assessments: A Post-Hoc Analysis from the IVIS Study. 视觉障碍对认知筛查评估完成的影响:来自IVIS研究的事后分析。
Q3 Medicine Pub Date : 2022-06-30 eCollection Date: 2022-01-01 DOI: 10.22599/bioj.263
James Bould, Lauren Hepworth, Claire Howard, Jim Currie, Fiona Rowe

Aim: The aim of this study was to evaluate completed cognitive screens in stroke survivors with and without visual impairment to explore whether the presence of visual impairment impacts on completion of cognitive screening.

Materials and methods: Cognitive screening assessment was undertaken using the Oxford Cognitive Screen (OCS). Data from visual function assessments (inclusive of visual acuity, visual fields, eye movements and visual perception evaluation) were analysed to determine whether presence and/or type of visual impairment impacted on cognitive screening scores achieved. Covariates, including glasses use, gender, age at stroke onset and stroke type, were used to assess confounding impacts on scores attained during cognitive screening.

Results: 1500 stroke admissions were recruited. One hundred ninety-seven who completed the OCS, were identified from the IVIS study database. Those who reported visual symptoms performed worse statistically on all cognitive tasks except the recall recognition (p = 0.232) and executive tasks (p = 0.967). Visual symptoms did not prevent participants from completing every section of the OCS (p = 0.095). In certain tasks, those not wearing their required glasses performed worse, including the executive function (p = 0.012), broken hearts and sentence reading tasks.

Conclusions: Many tasks within cognitive screening assessment are impacted by presence of visual deficits, and adjustments, where possible (e.g. good lighting, large print) should be used to facilitate completion of cognitive screening. It is important to ensure required reading correction is worn during screening.

目的:本研究的目的是评估有和无视力障碍的脑卒中幸存者完成的认知筛查,以探讨视力障碍的存在是否影响认知筛查的完成。材料和方法:认知筛查评估采用牛津认知筛查(OCS)。分析视觉功能评估(包括视力、视野、眼球运动和视觉感知评估)的数据,以确定是否存在和/或视觉障碍类型影响认知筛查得分。协变量,包括眼镜使用、性别、中风发病年龄和中风类型,被用来评估混杂因素对认知筛查得分的影响。结果:共纳入1500例卒中入院患者。从IVIS研究数据库中确定了197名完成OCS的患者。那些报告视觉症状的人在除回忆识别(p = 0.232)和执行任务(p = 0.967)外的所有认知任务中表现更差。视觉症状并未阻止参与者完成OCS的每个部分(p = 0.095)。在某些任务中,没有戴眼镜的人表现更差,包括执行功能(p = 0.012)、心碎和句子阅读任务。结论:认知筛查评估中的许多任务受到视觉缺陷存在的影响,并且在可能的情况下(例如良好的照明,大字体)应该使用调整来促进认知筛查的完成。确保在筛选过程中佩戴所需的读数校正是很重要的。
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引用次数: 1
Changes to Visual Parameters Following Virtual Reality Gameplay. 虚拟现实游戏后视觉参数的变化。
Q3 Medicine Pub Date : 2022-06-27 eCollection Date: 2022-01-01 DOI: 10.22599/bioj.257
Sanjog Banstola, Kerry Hanna, Anna O'Connor

Introduction: Virtual reality (VR) gameplay is popular with a range of games and educational resources available. However, it puts high demands on the visual system. Current evidence shows conflicting impacts on visual parameters. Therefore, this study explores the changes to vision following VR gameplay.

Methods: The study was conducted at the School of Health Sciences, University of Liverpool. All participants had binocular vision with good visual acuity and no manifest strabismus. Participants were assessed before and after playing 15 minutes of the VR game Beat Saber, which incorporated convergence and divergence movements. Clinical assessments including near point of convergence (NPC) and near point of accommodation (NPA) using the RAF rule; accommodative convergence to accommodation (AC/A) ratio; motor fusion using the prism fusion range (at 33cm), accommodation facility using +2.00/-2.00DS flipper lenses, and stereoacuity using the Frisby stereo test were assessed before and after playing.

Results: Seventy-eight participants (19-25 years old) were included in the study, with 16 males and 41 females respectively. The breakpoint of convergence reduced by 0.5 cm (p = 0.001). The binocular accommodative facility improved by 2 cycles per minute (cpm); p = 0.004. The mean, near horizontal prism fusion range (PFR) base break and recovery points both worsened by of 5.0 dioptres (p = 0.003), whereas the mean near horizontal PFR base in recovery point improved by of 4.0 dioptres (p = 0.003).

Discussion: The study validated previous findings as VR gameplay over-exercised and fatigued convergence muscles, but to a small degree. The VR experience improved the participants' ability to change focus quickly and improve accommodation, as well as the divergence function of the eye. However, as the participants were retested directly after the VR gameplay, the findings were limited to short term effects on vision.

导读:虚拟现实(VR)游戏是流行的一系列游戏和教育资源。然而,它对视觉系统的要求很高。目前的证据显示对视觉参数的影响相互矛盾。因此,本研究探讨了VR游戏后视觉的变化。方法:本研究在利物浦大学健康科学学院进行。所有受试者双眼视力良好,视力良好,无明显斜视。参与者在玩虚拟现实游戏《Beat Saber》之前和之后分别进行了15分钟的评估,该游戏包含了趋同和发散动作。临床评估,包括使用RAF规则的近汇聚点(NPC)和近适应点(NPA);调节收敛与调节(AC/A)比;运动融合采用棱镜融合范围(33cm),调节设施采用+2.00/-2.00DS鳍状透镜,立体视敏度采用弗里斯比立体测试。结果:共纳入受试者78人(年龄19-25岁),其中男性16人,女性41人。收敛断点降低了0.5 cm (p = 0.001)。双目调节设施提高2次/分(cpm);P = 0.004。近水平棱镜融合范围(PFR)基准点断裂和恢复点的平均值均下降了5.0屈光度(p = 0.003),而恢复点近水平PFR基准点的平均值提高了4.0屈光度(p = 0.003)。讨论:该研究证实了之前的发现,即VR游戏玩法过度锻炼和疲劳了收敛肌肉,但程度较小。VR体验提高了参与者快速改变焦点的能力,改善了适应性,以及眼睛的发散功能。然而,由于参与者在VR游戏后直接进行了重新测试,结果仅限于对视力的短期影响。
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引用次数: 5
Nystagmus in Down Syndrome - a Retrospective Notes Review. 唐氏综合症的眼球震颤-回顾笔记回顾。
Q3 Medicine Pub Date : 2022-06-21 eCollection Date: 2022-01-01 DOI: 10.22599/bioj.256
Dilys Oladiwura, Yusrah Shweikh, Clare Roberts, Maria Theodorou

Introduction: Nystagmus has been reported in up to 30% of people with Down Syndrome (DS), and yet is still not well understood. Our study aims to characterise the clinical features of patients with DS and nystagmus.

Methods: A retrospective medical-records review was conducted of all patients with a diagnosis of DS and nystagmus seen at Moorfields Eye Hospital over a ten-year period.

Results: Fifty-one subjects were identified, with complete data in 48. The mean age at presentation was 5.1 years (range 0-26 years). The mean binocular LogMAR visual acuity was 0.55(95%CI 0.53-0.57), mean refractive error was -1.8 Dioptre Sphere, DS (95% CI - 5.251.63) with -1.2 Dioptre Cylinder, DC (95% CI - 1.6-0.7). Ocular misalignment was found in 50% of patients. A diagnosis of Fusion Maldevelopment Nystagmus Syndrome (FMNS) was made in 6.3%, Infantile Nystagmus Syndrome (INS) in 8.4% and ABducting nystagmus/Inter-Nuclear Ophthalmoplegia (INO) in 2.1%. The descriptive term 'Manifest Horizontal Nystagmus'(MNH) was used in the majority, highlighting the difficulties in clinically differentiating the subtypes of nystagmus in DS. Eleven patients had associated cataract. Additional diagnoses unrelated to DS were made in 10.4%.

Conclusions: The most frequent type of nystagmus in our cohort was 'presumed' INS. This study highlights the importance of differentiating between FMNS and INS (with a latent component), so that further investigations can be performed as appropriate. Almost 25% had associated cataract, and a further 10% other diagnoses un-associated to DS. Despite INS being known to be associated with DS, further investigations may be required in a small subset with true INS after careful clinical assessment and use of eye movement recordings (where available).

导读:据报道,高达30%的唐氏综合征(DS)患者患有眼球震颤,但仍未得到很好的理解。我们的研究旨在描述退行性椎体滑移和眼球震颤患者的临床特征。方法:回顾性分析Moorfields眼科医院10年来诊断为退行性椎体滑移和眼球震颤的所有患者的医疗记录。结果:共纳入51例受试者,其中48例资料完整。平均发病年龄为5.1岁(范围0-26岁)。双眼平均LogMAR视力为0.55(95%CI 0.53-0.57),平均屈光误差为-1.8 Dioptre Sphere, DS (95%CI - 5.251.63)和-1.2 Dioptre Cylinder, DC (95%CI - 1.6-0.7)。50%的患者出现眼部错位。6.3%诊断为融合性发育不良眼震综合征(FMNS), 8.4%诊断为婴儿眼震综合征(INS), 2.1%诊断为外展性眼震/核间性眼麻痹(INO)。“明显水平眼震”(Manifest Horizontal Nystagmus, MNH)一词被广泛使用,突出了临床上区分退行性椎体滑移患者眼震亚型的困难。11例患者合并白内障。与退行性椎体滑移无关的附加诊断占10.4%。结论:我们的队列中最常见的眼球震颤类型为“推定”INS。本研究强调了区分FMNS和INS(有潜在成分)的重要性,因此可以酌情进行进一步的研究。近25%的患者伴有白内障,另有10%的患者的其他诊断与退行性椎体滑移无关。尽管已知INS与退行性痴呆有关,但在仔细的临床评估和使用眼动记录(如有)后,可能需要对一小部分真正INS患者进行进一步的调查。
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引用次数: 1
A Comprehensive Overview of Vision Screening Programmes across 46 Countries. 46个国家视力筛查规划的全面概述。
Q3 Medicine Pub Date : 2022-06-10 eCollection Date: 2022-01-01 DOI: 10.22599/bioj.260
Jill Carlton, Helen J Griffiths, Paolo Mazzone, Anna M Horwood, Frea Sloot

Purpose: To describe and compare vision screening programmes and identify variance in number and type of tests used, timing of screening, personnel involved, monitoring and funding to be used as data for optimising, disinvesting or implementing future screening programmes.

Methods: A questionnaire consisting of nine domains: demography & epidemiology, administration & general background, existing screening, coverage & attendance, tests, follow-up & diagnosis, treatment, cost & benefit and adverse effects was completed by Country Representatives (CRs) recruited from 47 countries.

Results: The questionnaire was sufficiently completed for 46 Countries: 42 European countries, China, India, Malawi and Rwanda. Variation of provision was found in; age of screening (0-17 years), tests included (23), types of visual acuity (VA) test used (35 different optotypes), personnel (13), number of screens per child (median 5, range 1-32), and times VA tested (median 3, range 1-30). Infant screening is offered in all countries, whereas childhood vision screening is offered at least once in all countries, but not all regions of each country. All 46 countries provide vision screening between the ages of 3-7 years. Data on screening outcomes for quality assurance was not available from most countries; complete evaluation data was available in 2% of countries, partial data from 43%.

Conclusion: Vision screening is highly variable. Some form of VA testing is being undertaken during childhood. Data collection and sharing should be improved to facilitate comparison and to be able to optimise vision screening programmes between regions and countries.

目的:描述和比较视力筛查方案,确定在使用的检查数量和类型、筛查时间、参与人员、监测和供资方面的差异,作为优化、减少投资或实施未来筛查方案的数据。方法:从47个国家招募的国家代表(CRs)完成了一份调查问卷,包括9个领域:人口统计学和流行病学、行政管理和一般背景、现有筛查、覆盖率和出席率、检测、随访和诊断、治疗、成本和收益以及不良反应。结果:46个国家:42个欧洲国家、中国、印度、马拉维和卢旺达完成了问卷。提供的变化发现于;筛查年龄(0-17岁),测试包括(23),使用的视力(VA)测试类型(35种不同的光型),人员(13),每个儿童的筛查次数(中位数5,范围1-32)和VA测试次数(中位数3,范围1-30)。所有国家都提供婴儿筛查,而所有国家都至少提供一次儿童视力筛查,但并非每个国家的所有地区。所有46个国家都提供3至7岁儿童的视力筛查。大多数国家没有关于质量保证筛查结果的数据;2%的国家有完整的评估数据,43%的国家有部分数据。结论:视力筛查具有高度可变性。一些形式的VA测试正在儿童时期进行。应改进数据收集和共享,以促进比较,并能够优化区域和国家之间的视力筛查规划。
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引用次数: 3
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British and Irish Orthoptic Journal
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