Pub Date : 2019-01-01DOI: 10.4018/IJRQEH.2019010105
Usharani Shola, V. Neelanarayanan
Target-controlled infusion pumps are for patients to control pain or to infuse sedations and anesthesia, typically those who underwent surgery. The pump has a programmable syringe device used to control the injection level of drugs. These pumps are even used in the ICU or operating theaters to manage patient's pain after surgery or sedation. PK-PD Models are used to obtain the drug concentrations levels of the patient. The model depends on the drug flow rates in different parts of the body. There are many parameter sets available to measure the amount of drugs in the patients. This article presents a three compartmental patient model through Simulink to obtain concentrations levels from different parts of the body. The model is checked for a seven parameter set and suggests the set with the best results.
{"title":"Comparative Study of 4-Compartmental PK-PD Model with Effective Site Compartment for Different Parameter Set","authors":"Usharani Shola, V. Neelanarayanan","doi":"10.4018/IJRQEH.2019010105","DOIUrl":"https://doi.org/10.4018/IJRQEH.2019010105","url":null,"abstract":"Target-controlled infusion pumps are for patients to control pain or to infuse sedations and anesthesia, typically those who underwent surgery. The pump has a programmable syringe device used to control the injection level of drugs. These pumps are even used in the ICU or operating theaters to manage patient's pain after surgery or sedation. PK-PD Models are used to obtain the drug concentrations levels of the patient. The model depends on the drug flow rates in different parts of the body. There are many parameter sets available to measure the amount of drugs in the patients. This article presents a three compartmental patient model through Simulink to obtain concentrations levels from different parts of the body. The model is checked for a seven parameter set and suggests the set with the best results.","PeriodicalId":36298,"journal":{"name":"International Journal of Reliable and Quality E-Healthcare","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4018/IJRQEH.2019010105","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45143980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-10-01DOI: 10.4018/IJRQEH.2018100104
S. Bello
The central objective of this study was to determine the level of awareness and use of Electronic Health Information Resources (EHIRs) among the Academic Physicians of College of Medicine, University of Ibadan (COMUI), Nigeria. Others were to find out the frequency of use, the purposes and barriers against the use. Two hypotheses formulated and tested. This is a total enumeration research with 265 COMUI Academic Physicians, Nigeria. Questionnaire, designed with nominal and dichotomous questions was used. Data collected was analyzed with SPSS version 20.0. Descriptive statistics was used. Test of Pearson Moment Correlation (PMC) with Independent Sample t – test at 5% p – value used. The Academic Physicians mean age was 37.75. The results obtained indicated variations: 96.0% aware and used HINARI, 94.0% aware and used PubMed/Medline, NCBI was 64.9%. Hypothesis Test between awareness and use of EHIRs signified coefficient of proportionality (r = 218, p < 05).
本研究的中心目标是确定尼日利亚伊巴丹大学医学院学术医师对电子卫生信息资源(EHIRs)的认识和使用水平。另一项是找出使用频率、目的和使用障碍。提出并验证了两个假设。这是对尼日利亚265名COMUI学术医师的总枚举研究。问卷采用标称题和二分题设计。收集的数据用SPSS 20.0版进行分析。采用描述性统计。Pearson矩相关检验(PMC)采用独立样本t检验，p值为5%。学术医师的平均年龄为37.75岁。结果显示，有96.0%的人知道并使用HINARI, 94.0%的人知道并使用PubMed/Medline, 64.9%的人知道并使用NCBI。假设检验表明，意识与EHIRs使用之间存在显著的比例系数(r = 218, p < 0.05)。
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Pub Date : 2018-10-01DOI: 10.4018/IJRQEH.2018100103
Xenofon Liapakis
Data Protection has always been an issue of concern for businesses across the globe. Laws addressing the Universal Statement for Human Rights have been set as early as 1948 and, as years go by, awareness further strengthens legislative actions. Through his work at Interamerican insurance company, the author shows that alignment with legislation, though perceived as a resource-intensive, counter-productive process, may be turned into an opportunity for fine tuning, promoting the operations of a company, and raising the trust towards IT.
{"title":"A GDPR Implementation Guide for the Insurance Industry","authors":"Xenofon Liapakis","doi":"10.4018/IJRQEH.2018100103","DOIUrl":"https://doi.org/10.4018/IJRQEH.2018100103","url":null,"abstract":"Data Protection has always been an issue of concern for businesses across the globe. Laws addressing the Universal Statement for Human Rights have been set as early as 1948 and, as years go by, awareness further strengthens legislative actions. Through his work at Interamerican insurance company, the author shows that alignment with legislation, though perceived as a resource-intensive, counter-productive process, may be turned into an opportunity for fine tuning, promoting the operations of a company, and raising the trust towards IT.","PeriodicalId":36298,"journal":{"name":"International Journal of Reliable and Quality E-Healthcare","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4018/IJRQEH.2018100103","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47320520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-07-01DOI: 10.4018/IJRQEH.2018070101
Hakan Altınpulluk
This article aims to examine the mobile health (mHealth) in education articles in journals covered by the SSCI and SCI-EXPANDED indices between 2000-2016. Five hundred and ninety-four (594) articles have been analyzed with a systematic review method. The change of the articles by year, the distribution according to the countries, universities, authors, citation analysis, and research fields were examined. As a result of this research, it was determined that the articles and citations have tended to increase rapidly after 2012. The US plays a pioneering role in this field, the universities in the USA publish most of the articles on the subject, and the USA-based authors dominate the field. In addition, it has been determined that mHealth-related articles tend to increase in undeveloped and developing countries, where mHealth projects are concentrated. Finally, based on research findings, some suggestions were made for researchers, developers and practitioners.
{"title":"A Systematic Review of Mobile Health in Education From 2000 to 2016","authors":"Hakan Altınpulluk","doi":"10.4018/IJRQEH.2018070101","DOIUrl":"https://doi.org/10.4018/IJRQEH.2018070101","url":null,"abstract":"This article aims to examine the mobile health (mHealth) in education articles in journals covered by the SSCI and SCI-EXPANDED indices between 2000-2016. Five hundred and ninety-four (594) articles have been analyzed with a systematic review method. The change of the articles by year, the distribution according to the countries, universities, authors, citation analysis, and research fields were examined. As a result of this research, it was determined that the articles and citations have tended to increase rapidly after 2012. The US plays a pioneering role in this field, the universities in the USA publish most of the articles on the subject, and the USA-based authors dominate the field. In addition, it has been determined that mHealth-related articles tend to increase in undeveloped and developing countries, where mHealth projects are concentrated. Finally, based on research findings, some suggestions were made for researchers, developers and practitioners.","PeriodicalId":36298,"journal":{"name":"International Journal of Reliable and Quality E-Healthcare","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4018/IJRQEH.2018070101","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43075583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-07-01DOI: 10.4018/IJRQEH.2018070102
Theodoros Argyropoulos, P. Foukas, Effrosyni Karakitsou, Stefanos Konstantoudakis, M. Kefala, Nektarios Koufopoulos, N. Machairas, I. Panayiotides, K. Triantafyllou
This article describes how colorectal carcinomas (CRC) are the fourth most frequently diagnosed cancer. However, despite advances in specific treatment, approximately 40% to 50% of patients have disease recurrence following potentially curative surgery, highlighting the demand for improvement of staging, treatment and prognosis. Inflammatory infiltration composed of lymphocytes is a common feature found in neoplasms and studies have indicated an association between tumor immune infiltrates and favorable disease outcomes. The aim of this article is to assess the association of tumor infiltrating lymphocytes and DNA damage response expression levels with disease outcome and survival in stage II and III CRC. The authors examined the prognostic value of immunological biomarkers using 5-year follow-up data to train an Artificial Neural Network (ANN) designed for the prediction of personalized risk. Data for three biomarkers which were found significant were subsequently used to train the ANN which predicted 5-year survival with 72.9% sensitivity and 68.8% specificity.
{"title":"Predictive Value of CD3, CD8, CD45RO Expression in Stage II/III Colorectal Cancer","authors":"Theodoros Argyropoulos, P. Foukas, Effrosyni Karakitsou, Stefanos Konstantoudakis, M. Kefala, Nektarios Koufopoulos, N. Machairas, I. Panayiotides, K. Triantafyllou","doi":"10.4018/IJRQEH.2018070102","DOIUrl":"https://doi.org/10.4018/IJRQEH.2018070102","url":null,"abstract":"This article describes how colorectal carcinomas (CRC) are the fourth most frequently diagnosed cancer. However, despite advances in specific treatment, approximately 40% to 50% of patients have disease recurrence following potentially curative surgery, highlighting the demand for improvement of staging, treatment and prognosis. Inflammatory infiltration composed of lymphocytes is a common feature found in neoplasms and studies have indicated an association between tumor immune infiltrates and favorable disease outcomes. The aim of this article is to assess the association of tumor infiltrating lymphocytes and DNA damage response expression levels with disease outcome and survival in stage II and III CRC. The authors examined the prognostic value of immunological biomarkers using 5-year follow-up data to train an Artificial Neural Network (ANN) designed for the prediction of personalized risk. Data for three biomarkers which were found significant were subsequently used to train the ANN which predicted 5-year survival with 72.9% sensitivity and 68.8% specificity.","PeriodicalId":36298,"journal":{"name":"International Journal of Reliable and Quality E-Healthcare","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4018/IJRQEH.2018070102","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41595587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-07-01DOI: 10.4018/IJRQEH.2018070104
S. Naqvi, A. Shah
This article describes how mobile health (mHealth) has grown from infancy stage to toddler stage due to advances in the technology. It has the potential for further growth as it is low-cost health care. For its further growth, it is necessary to widen its scope. In this article, a proposal is presented to develop a new and advanced mHealth care system, and its first step that is modelling is reported. In modelling, historically, a model of a temporal object system (TOS) is used. The model empowers users of the proposed mHealth care system to define, retrieve and manipulate all objects historically, in a uniform fashion, and also to keep historically the changes that occur to the objects. Later, these historically stored objects can be consulted during making essential and crucial decisions about the patients (objects) and other objects of the system, and it can save both lives and money. Also, the stored objects can be used in the future planning and research.
{"title":"Modeling Historically mHealth Care Environments","authors":"S. Naqvi, A. Shah","doi":"10.4018/IJRQEH.2018070104","DOIUrl":"https://doi.org/10.4018/IJRQEH.2018070104","url":null,"abstract":"This article describes how mobile health (mHealth) has grown from infancy stage to toddler stage due to advances in the technology. It has the potential for further growth as it is low-cost health care. For its further growth, it is necessary to widen its scope. In this article, a proposal is presented to develop a new and advanced mHealth care system, and its first step that is modelling is reported. In modelling, historically, a model of a temporal object system (TOS) is used. The model empowers users of the proposed mHealth care system to define, retrieve and manipulate all objects historically, in a uniform fashion, and also to keep historically the changes that occur to the objects. Later, these historically stored objects can be consulted during making essential and crucial decisions about the patients (objects) and other objects of the system, and it can save both lives and money. Also, the stored objects can be used in the future planning and research.","PeriodicalId":36298,"journal":{"name":"International Journal of Reliable and Quality E-Healthcare","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4018/IJRQEH.2018070104","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46661151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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