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The Prevalence of Hepatitis Delta Virus in Patients with Chronic Hepatitis B and Its Association with Risk Factors 慢性乙型肝炎患者中德尔塔病毒的患病率及其与危险因素的关系
Q4 Medicine Pub Date : 2019-01-20 DOI: 10.5812/MEJRH.84112
F. Bineshian, Z. Sharifi
Background: Hepatitis B infection is a serious health problem and two billion people worldwide are infected with the virus. The hepatitis delta virus (HDV) is a satellite virus. Hepatitis D virus infection in HBsAg carriers can be present as a simultaneous and acute infection. Objectives: The aim of this study was toevaluate the frequency of HDVin patients with chronichepatitis B and itsassociation with risk factors. Methods: Inthisdescriptivestudy,74patientswithchronicHBVinfectionwereselectedfrompatientsthathadreferredtotheClin-icalLabof BloodTransfusionOrganization. AllpatientswerepositiveforHBsAgformorethansixmonthsandanti-HBc. Allsamples werenegativeforHIVandHCV.Ananti-HDVtestwasperformedonHBsAg-positivespecimensbytheenzymelinkedimmunosorbent assay (ELISA) method. Also, HBV-real-time polymerase chain reaction (PCR) testing was done to determine the viral load. Results: In this study, 74 HBsAg positive patients with a mean age of 50.22 ± 15.09 years were studied. Five (6.8%) patients had anti-HDV antibodies. Furthermore, 60% of the patients with HDV had risk factors, such as addiction, family history of hepatitis B, and a history of surgery. Maximal viral load in plasma samples of patients with anti-HDV antibodies, 531 IU/mL, was determined. Conclusions: For prevention of HDV transmission, all patients of chronic hepatitis B with low-level viral load should be evaluated for hepatitis D infection. Also, for determining the relationship between HDV infections with its risk factors, another study with a larger sample size should be performed.
背景:乙型肝炎感染是一个严重的健康问题,全世界有20亿人感染了这种病毒。德尔塔型肝炎病毒(HDV)是一种卫星病毒。乙型肝炎表面抗原携带者中的丁型肝炎病毒感染可以同时存在和急性感染。目的:本研究旨在评估慢性乙型肝炎HDVin患者的发病率及其与危险因素的关系。方法:在本描述性研究中,选择74例慢性乙型肝炎病毒感染者作为推荐给输血组织临床实验室的对照组。所有患者的HBsAg均在6个月以上,抗-HBc均呈阳性。所有样本均为HIVan和HCV阴性。用酶联免疫吸附试验(ELISA)方法对hBsAg阳性样本进行了Ananti-HDV检测。此外,还进行了HBV实时聚合酶链式反应(PCR)检测以确定病毒载量。结果:本研究对74例HBsAg阳性患者进行了研究,平均年龄50.22±15.09岁。5名(6.8%)患者具有抗HDV抗体。此外,60%的HDV患者有成瘾、乙型肝炎家族史和手术史等危险因素。测定了具有抗HDV抗体的患者血浆样本中的最大病毒载量531 IU/mL。结论:为了预防HDV的传播,所有病毒载量低的慢性乙型肝炎患者都应进行丁型肝炎感染评估。此外,为了确定HDV感染与其风险因素之间的关系,应该进行另一项更大样本量的研究。
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引用次数: 0
Outpatients’ Satisfaction with the Provision of Physiotherapy Services 门诊病人对物理治疗服务的满意度
Q4 Medicine Pub Date : 2019-01-20 DOI: 10.5812/MEJRH.69431
A. Rufa’i, I. Saidu, Muhammad Dahiru Lawan, A. Oyeyemi, S. Aliyu, A. Lawan, Abdurrahman Mohammed Jajere, Adetoyeje Y. Oyeyemi
Background: Patient satisfaction is one of the indicators of the quality of care received by patients, which can be used as a benchmark to ensure quality of physiotherapy services. However, there is a dearth of data in Nigeria. Objectives: The current study aimed at examining the level of patients’ satisfaction with the physiotherapy services in Maiduguri, Nigeria. Methods: The current cross sectional study was conducted on a total of 300 participants (158 males and 142 females) randomly recruited from the physiotherapy outpatient unit of three hospitals. The physical therapy satisfaction questionnaire was administered to assess the participants’ level of satisfaction with the rendered physiotherapy services. Results: The overall patient satisfaction score was 82.95 ± 14.71. Privacy was the highest satisfactory subscale reported by the participants (83.50 ± 11.21), while facility locations/proximity (68.51 ± 13.20) and bills/cost (70.24 ± 19.40) were the least satisfactory subscales among the others. The result shows that female and old adult participants were significantly more satisfied with the received physiotherapy services compared with the male and young adult participants (P = 0.03 and 0.001, respectively). However, participants did not differ significantly in the level of satisfaction with provided physiotherapy services in terms of their conditions/ailments (P = 0.056). Conclusions: Overall, patient satisfaction with physiotherapy services in the current study was high. Females, older adults, as well as employed participants were more satisfied. Also, higher satisfaction was observed among participants with primary school education and the ones receiving multiple treatment modalities.
背景:患者满意度是患者接受护理质量的指标之一,可以作为保证物理治疗服务质量的基准。然而,尼日利亚缺乏相关数据。目的:本研究旨在调查尼日利亚迈杜古里地区患者对物理治疗服务的满意度。方法:本研究采用横断面研究方法,随机从三家医院的物理治疗门诊部门招募300名参与者,其中男性158人,女性142人。通过物理治疗满意度问卷来评估参与者对所提供的物理治疗服务的满意度。结果:患者总体满意度为82.95±14.71分。参与者对隐私的满意度最高(83.50±11.21),对设施位置/邻近性(68.51±13.20)和费用/成本(70.24±19.40)的满意度最低。结果显示,女性和老年受试者对所接受的物理治疗服务的满意度显著高于男性和青年受试者(P = 0.03和0.001)。然而,参与者对所提供的物理治疗服务的满意度在他们的状况/疾病方面没有显着差异(P = 0.056)。结论:总体而言,本研究中患者对物理治疗服务的满意度较高。女性、老年人和在职参与者的满意度更高。此外,接受过小学教育及多种治疗方式的参与者满意度较高。
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引用次数: 6
“Study of Neuromuscular and Proprioceptive Training Program on Postural Stability in Active Middle-Aged Men” “神经肌肉和本体感觉训练方案对活跃中年男性体位稳定性的研究”
Q4 Medicine Pub Date : 2019-01-14 DOI: 10.5812/MEJRH.84958
Mohammadreza Rezaeipour, Vladimir Ivanovich Nychyporuk
Background: The risk of falling increases with age, and the outcome might sometimes be severe injury or even death. Objectives: This study was designed to determine whether a 12-week neuromuscular and proprioceptive training (NPT) plan was impressive on postural stability of active middle-aged men. Methods: The study had a quasi-experimental design with a control group. In 2016, 50 middle-aged males of the Ukrainian Sports Medicine Center (Kiev) were randomly divided to experimental (performed the NPT program, rather than general warm-up routines) and control groups (maintained the general warm-up routines). The mean center of pressure (CoP) fluctuations of postural stabilitywasassessedduringeyesopen(EO)andclosed(EC)usingaforceplatforminthetwodirections,beforeandafterthe12-week study. Results: TheinterventionleadstoasignificantimprovementinthemeanCoPvelocityinbothplanes(P< 0.05)intheexperimental group compared to the control. All CoP parameters used in this study showed very large correlations. Conclusions: The NPT program had a positive effect on postural stability. This may have a direct impact on reducing lower limb injury in middle-aged men.
背景:跌倒的风险随着年龄的增长而增加,结果有时可能是严重的伤害甚至死亡。目的:本研究旨在确定为期12周的神经肌肉和本体感觉训练(NPT)计划是否对活跃中年男性的姿势稳定性有显著影响。方法:采用准实验设计,设对照组。2016年,乌克兰运动医学中心(基辅)的50名中年男性被随机分为实验组(执行NPT程序,而不是一般的热身程序)和对照组(保持一般的热身程序)。在为期12周的研究之前和之后,使用一个力平台在两个方向上评估眼睛睁开(EO)和闭上(EC)期间姿势稳定性的平均压力中心(CoP)波动。结果:实验组与对照组相比,干预对两平面平均车速均有显著的改善作用(P< 0.05)。本研究中使用的所有CoP参数均显示出非常大的相关性。结论:NPT方案对体位稳定性有积极作用。这可能对减少中年男性下肢损伤有直接影响。
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引用次数: 0
Survival Status and Predictors of Loss to Follow-up Among Adult Patients with Tuberculosis on Follow-up and Care in Public Health Facilities of Sheka Zone, South-West Ethiopia: Facility-Based, Retrospective Cohort Study 埃塞俄比亚西南部谢卡区公共卫生机构随访和护理的成年结核病患者的生存状况和随访损失的预测因素:基于设施的回顾性队列研究
Q4 Medicine Pub Date : 2019-01-14 DOI: 10.5812/MEJRH.84068
T. Shaweno, Masrie Getnet, Chaltu Fikru
Background: Treatment success rate and loss to follow-up (LTFU) in patient with tuberculosis (TB) are a great concern in Ethiopia. However, available information is inadequate to assess the magnitude of LTFU and its predictors in geographically remote regions of Ethiopia. Objectives: The current study aimed at assessing the survival status and predictors of LTFU among adult patients with tuberculosis registered in TB treatment and care center in public health institutions of Sheka Zone, South-West Ethiopia. Methods: A facility-based, retrospective cohort study was conducted from 01 to 30 August 2016. The LTFU was defined as patient with tuberculosis under follow-up being lost before treatment initiation or treatment interruption for two or more successive months. Kaplan-Meir curve and Cox proportional hazard model were fitted to determine survival time and predictors with survival status, respectively. Results: A total of 1319 patients with tuberculosis were followed up for a total of 7056.87 months from treatment initiation to outcomes. Of these, 117 (8.9%) patients were lost. The survival status at the completion of the intensive and continuation phases was 93.7% and 90%, respectively. Living farther than 10 Km away from the nearest health facility (adjusted odds ratio (AHR) = 4.9, 95% confidence interval (CI): 3.02 - 12.50) and not being adhered to anti-retroviral therapy (AHR = 5.3, 95%CI: 1.63 - 8.12) were significantly associated with LTFU. Conclusions: Significant TB patient LTFU was observed during the first two months of treatment and care. LTFU was high in patients not adhered to antiretroviral therapy (ART) and living far.
背景:在埃塞俄比亚,结核病(TB)患者的治疗成功率和随访损失(LTFU)是一个非常令人关注的问题。然而,现有资料不足以评估埃塞俄比亚地理上偏远地区LTFU的规模及其预测因素。目的:本研究旨在评估埃塞俄比亚西南部谢卡区公共卫生机构结核病治疗和护理中心登记的成年结核病患者LTFU的生存状况和预测因素。方法:2016年8月1日至30日进行了一项以医院为基础的回顾性队列研究。LTFU定义为随访的结核病患者在治疗开始或治疗中断前连续两个月或更长时间丢失。拟合Kaplan-Meir曲线和Cox比例风险模型,分别确定生存时间和生存状况的预测因子。结果:1319例结核病患者从治疗开始到治疗结束,共随访7056.87个月。其中117例(8.9%)患者丢失。强化期和延续期结束时生存率分别为93.7%和90%。居住在距离最近的医疗机构超过10公里的地方(调整优势比(AHR) = 4.9, 95%可信区间(CI): 3.02 - 12.50)和未坚持抗逆转录病毒治疗(AHR = 5.3, 95%CI: 1.63 - 8.12)与LTFU显著相关。结论:结核病患者在治疗和护理的前两个月观察到显著的LTFU。未坚持抗逆转录病毒治疗(ART)且生活较远的患者LTFU较高。
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引用次数: 1
Electromyographic Activities of Cervical Muscles While Using an Oscillating Blade Held in the Mouth: Influence of Different Swings 使用口含摆动刀片时颈部肌肉的肌电图活动:不同摆动方式的影响
Q4 Medicine Pub Date : 2019-01-12 DOI: 10.5812/MEJRH.85546
H. Ishida, T. Suehiro, Susumu Watanabe
Background: Neck pain is one of the most prevalent musculoskeletal conditions. Manual mobilization plus exercise are recom-mendedfortreatingpeoplewithacuteneckpainwithmovementcoordinationimpairments. Therefore,itisimportanttoconsider asafeandeffectivecoordinationexerciseforthecervicalmuscles. Usinganoscillatingdevicebyholdingitinthemouthmightbea type of coordination exercise for the cervical muscles. Objectives: This study aimed to compare the activities of the cervical muscles while using an oscillating blade held in the mouth with different swings. Methods: Ten healthy male university students participated in this study (20.8 ± 0.9 years). The activities of the sternocleidomastoid and cervical extensor muscles were measured using electromyography while using an oscillating blade held in the mouth in horizontal orientation (up-down oscillation). Participants were asked to oscillate the device in one of the following swings: Cervical flexion-extension and knee flexion-extension. Both exercises were performed in a standing position. All EMG activities were normalized by EMG activities during maximum voluntary contractions of those muscles. Results: The activities of the sternocleidomastoid with knee flexion-extension (5.7 ± 4.8 %) present significantly lower muscle activities (P = 0.011) than those with cervical flexion-extension (12.2 ± 8.6%). The activities of the cervical extensor muscles with knee flexion-extension (10.7 ± 6.5%) present significantly lower muscle activities (P < 0.001) than those with cervical flexion-extension (17.5 ± 10.3%). Conclusions: Theresultsofthisstudyindicatedthattheexercisewithkneeflexion-extensionhadlowerloadforthecervicalmuscles than that with cervical flexionextension. The findings of this study could be basic information for grading intensity of cervical coordination exercise using an oscillating blade held in the mouth. using
背景:颈部疼痛是最常见的肌肉骨骼疾病之一。建议采用人工动员加锻炼的方法,在运动协调的情况下治疗颈痛患者。因此,重要的是要考虑到子宫肌的安全性和有效的协调训练。使用振荡装置保持血液透析可能是一种颈部肌肉的协调运动。目的:本研究旨在比较在不同摆动情况下使用口腔摆动刀片时颈部肌肉的活动。方法:10名健康男大学生(20.8±0.9岁)参加本研究。使用肌电图测量胸锁乳突肌和颈伸肌的活动,同时使用口腔中保持水平方向的振荡刀片(上下振荡)。参与者被要求以以下摆动方式之一摆动该装置:颈部屈曲伸展和膝盖屈曲伸展。两项练习都是站着进行的。所有的肌电图活动都通过这些肌肉最大程度自主收缩期间的肌电图活动进行标准化。结果:膝屈伸后的胸锁乳突肌活动(5.7±4.8%)明显低于颈屈伸后(12.2±8.6%)的肌肉活动(P=0.011)。膝屈伸前的颈伸肌活动(10.7±6.5%)明显低于颈部伸肌(P<0.001)屈伸术(17.5±10.3%)。这项研究的结果可能是使用口腔中的振荡刀片对颈部协调运动强度进行分级的基本信息。使用
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引用次数: 0
Effect of Botulinum Toxin A (BTX-A) Injection into Denervated Muscles on Synkinesis and Symmetry in Patients with Facial Nerve Paralysis 失神经肌肉注射肉毒毒素A(BTX-A)对面神经麻痹患者运动机能和对称性的影响
Q4 Medicine Pub Date : 2018-11-27 DOI: 10.15406/JOENTR.2018.10.00388
Abbas A Pourmomeny
Context: Synkinesisreferstoaninvoluntarymovementaccompanyingavoluntaryonethatisaconsequenceof facialparalysis. The cosmetic procedure is used for the management of synkinesis that results in facial symmetry. Botulinum A toxin (BTX-A) has been used for more than two decades for resolving asymmetry and synkinesis. However, the endpoints remain to be further explained. The purpose of this study was to analyze research trends in facial synkinesis and asymmetry after facial nerve palsy (FNP). Evidence Acquisition: The databases Medline, PubMed, ScienceDirect, CINHAL, Scopus, and ProQuest were searched for articles published between 1970 and 2017 using the keywords, ‘facial paralysis’, ‘Bell’s palsy’, ‘synkinesis’, and ‘Botulinum A toxin’. Results: Intotal,13eligiblearticles,cumulativelyexamining332patients,enteredtheanalysis. Theyweredividedintothreegroups as follows. Eight articles in group I were taken as case series with 181 patients. Two articles in group II compared BTX-A and neuromuscular rehabilitation with 61 patients. Both these groups concluded that BTX-A injection could help reduce synkinesis. In group III, only were three randomized clinical trials retrieved with 90 patients that reported disparate findings. Conclusions: BTX-A injection cannot yet be proposed as a solution for synkinesis reduction to achieve symmetry and overcome this complication of facial nerve palsy because of the small number of randomized clinical trials available on the subject. Further studies are recommended to be able to make a firm conclusion.
上下文:突触运动是指一种自愿的运动,伴随着避免面部麻痹导致的长期死亡。美容手术是用于管理导致面部对称的联合运动。肉毒杆菌毒素A(BTX-A)已被用于解决不对称性和联合作用超过20年。然而,终点还有待进一步解释。本研究的目的是分析面神经麻痹(FNP)后面部联合和不对称的研究趋势。证据获取:在Medline、PubMed、ScienceDirect、CINHAL、Scopus和ProQuest数据库中搜索1970年至2017年间发表的文章,关键词为“面瘫”、“Bell’s麻痹”、“联合运动”和“肉毒杆菌毒素A”。结果:共13篇合格文章,累计检查332例,进入分析。他们提供给三组,如下所示。第一组8篇文章作为181例患者的病例系列。第二组的两篇文章对61名患者的BTX-A和神经肌肉康复进行了比较。这两个小组都得出结论,BTX-A注射可以帮助减少联合运动。在第三组中,仅检索了三项随机临床试验,共有90名患者报告了不同的结果。结论:BTX-A注射液还不能被提议作为减少联合运动的解决方案,以实现对称性并克服面神经麻痹的这种并发症,因为该受试者的随机临床试验数量很少。建议进行进一步研究,以便得出明确结论。
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引用次数: 0
Environmental Health and Safety Status in the Primary Schools of Garmsar City, Iran 伊朗加尔萨尔市小学环境健康与安全状况
Q4 Medicine Pub Date : 2018-10-21 DOI: 10.5812/MEJRH.69426
S. Abolli, A. Abdolshahi, M. Mohseni, Safiye Ghobakhloo
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引用次数: 3
Pesticide Multiresidue Analysis in Tomato and Cucumber Samples Collected from Fruit and Vegetable Markets in Tehran, Iran 伊朗德黑兰水果和蔬菜市场番茄和黄瓜样品农药多重残留分析
Q4 Medicine Pub Date : 2018-10-10 DOI: 10.5812/MEJRH.64271
Hadi Amrollahi, R. Pazoki, S. Imani
Background: The organophosphorus pesticides are still applied in some developing countries including most regions of Iran. It is important to make sure that the level of pesticide residues at the time of harvesting vegetable crops (e.g. tomato and cucumber) is assessed in order to control that their levels are within the permissible limit in the domestic as well as overseas markets; and most importantly the governments should ban the application of such compounds. Regarding the increasing consumption of pesticides in agriculture, the current study aimed at determining the amount of pesticide residues in crops such as tomatoe and cucumber to ensure that Codex maximum residue limit (MRL) alimentarius is not violated. Methods: A simple multiresidue method, using gas chromatography-mass spectrometry (GC-MS) and solid phase extraction, was employed to detect the pesticides with a sufficient extraction method. Results: The lowest level of pesticide residues were concerning carbaryl, fenpropat, and endosulfan in cucumber samples selected from greenhouses and fields with 11.1%, while the highest level was concerning diazinon in cucumber samples of the fields with 55.5%. Carbaryl and permethrin showed the high residue means of 0.37 and 0.72 µg/g in tomato and cucumber samples, respectively. Conclusions: Vegetables and fruits with a high level of pesticide residues, which particularly violated the MRL, are sold in markets of Tehran, Iran. Therefore, it is suggested that the application of pesticides on fields and greenhouses be controlled and their residue levels be measured using the multiresidue method before distribution. The current study findings showed that the multi-residue method with GC/MS could detect a large number of pesticide residues at the same time with high accuracy. Therefore, it is recommended that this method be employed for all vegetables and fruits in order to assess their pesticide residue levels before reaching the markets.
背景:包括伊朗大部分地区在内的一些发展中国家仍在使用有机磷农药。重要的是要确保在收获蔬菜作物(例如番茄和黄瓜)时评估农药残留水平,以控制其水平在国内和海外市场的允许限度内;最重要的是,政府应该禁止使用这些化合物。针对农业中农药使用量的不断增加,本研究旨在确定番茄和黄瓜等作物中农药残留的数量,以确保不违反食品法典最高残留限量(MRL)。方法:采用气相色谱-质谱联用、固相萃取的简易多残留法,提取方法充分,对农药进行检测。结果:温室和田间黄瓜样品中农药残留量最低的是西威因、苯丙帕和硫丹,残留量为11.1%;田间黄瓜样品中农药残留量最高的是二嗪农,残留量为55.5%。威威利和氯菊酯在番茄和黄瓜样品中的高残留平均值分别为0.37和0.72µg/g。结论:在伊朗德黑兰市场上销售的蔬菜和水果农药残留水平高,特别违反了最大残留限量。因此,建议控制农药在田间和大棚的施用,并在分配前采用多重残留法测定农药残留量。本研究结果表明,GC/MS多残留法可同时检测大量农药残留,且准确度较高。因此,建议所有蔬菜和水果都采用这种方法,以便在进入市场之前评估其农药残留水平。
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引用次数: 10
Determination of Spatial Resolution in Children Seven to Twelve Years Old by Box and Block Test and Nine Hole Peg Test 盒块测验和九孔钉测验测定7-12岁儿童空间分辨率
Q4 Medicine Pub Date : 2018-10-06 DOI: 10.5812/MEJRH.64343
A. Ziari, Vali Valizadeh, Javad Marzban, M. Mirshoja
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引用次数: 0
Development of Maintenance Treatment Centers for Comprehensive Rehabilitation Services Clinics for Drug Abuse Based on Lifestyle Modification 基于生活方式改变的综合康复服务诊所维持治疗中心的发展
Q4 Medicine Pub Date : 2018-10-06 DOI: 10.5812/MEJRH.84552
Behzad Heydarpour, Mozhgan Saeidi, Saeid Komasi
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引用次数: 0
期刊
Middle East Journal of Rehabilitation and Health
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