Pub Date : 2022-08-23DOI: 10.1007/s40472-022-00375-0
J. Villanueva, Y. Joshi, S. Emmanuel, L. Gao, P. Macdonald
{"title":"Expanding Donor Heart Utilization Through Machine Perfusion Technologies","authors":"J. Villanueva, Y. Joshi, S. Emmanuel, L. Gao, P. Macdonald","doi":"10.1007/s40472-022-00375-0","DOIUrl":"https://doi.org/10.1007/s40472-022-00375-0","url":null,"abstract":"","PeriodicalId":36387,"journal":{"name":"Current Transplantation Reports","volume":"9 1","pages":"219 - 226"},"PeriodicalIF":2.1,"publicationDate":"2022-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46652608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-09DOI: 10.1007/s40472-022-00371-4
Carolin Hermanns, Omar Paulino da Silva Filho, Vijayganapathy Vaithilingam, A. V. van Apeldoorn
{"title":"The Potential of Cell Sheet Technology for Beta Cell Replacement Therapy","authors":"Carolin Hermanns, Omar Paulino da Silva Filho, Vijayganapathy Vaithilingam, A. V. van Apeldoorn","doi":"10.1007/s40472-022-00371-4","DOIUrl":"https://doi.org/10.1007/s40472-022-00371-4","url":null,"abstract":"","PeriodicalId":36387,"journal":{"name":"Current Transplantation Reports","volume":"9 1","pages":"199 - 208"},"PeriodicalIF":2.1,"publicationDate":"2022-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46149163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-06DOI: 10.1007/s40472-022-00373-2
M. Chávez-Villa, L. Ruffolo, K. Tomiyama, R. Hernandez‐Alejandro
{"title":"Where Are We Now With Liver Transplant for Colorectal Metastasis?","authors":"M. Chávez-Villa, L. Ruffolo, K. Tomiyama, R. Hernandez‐Alejandro","doi":"10.1007/s40472-022-00373-2","DOIUrl":"https://doi.org/10.1007/s40472-022-00373-2","url":null,"abstract":"","PeriodicalId":36387,"journal":{"name":"Current Transplantation Reports","volume":"9 1","pages":"257 - 266"},"PeriodicalIF":2.1,"publicationDate":"2022-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48546412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-06DOI: 10.1007/s40472-022-00374-1
Diana A. Wu, G. Oniscu
{"title":"Piloting Uncontrolled DCD Organ Donation in the UK; Overview, Lessons and Future Steps","authors":"Diana A. Wu, G. Oniscu","doi":"10.1007/s40472-022-00374-1","DOIUrl":"https://doi.org/10.1007/s40472-022-00374-1","url":null,"abstract":"","PeriodicalId":36387,"journal":{"name":"Current Transplantation Reports","volume":"9 1","pages":"250 - 256"},"PeriodicalIF":2.1,"publicationDate":"2022-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46261147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-01Epub Date: 2022-03-16DOI: 10.1007/s40472-021-00340-3
Yasar Caliskan, Brian Lee, Adrian Whelan, Fadee Abualrub, Krista L Lentine, Arksarapuk Jittirat
Purpose of review: To provide a comprehensive update on the role of genetic testing for the evaluation of kidney transplant recipient and living donor candidates.
Recent findings: The evaluation of candidates for living donor transplantation and their potential donors occur within an ever-changing landscape impacted by new evidence and risk assessment techniques. Criteria that were once considered contraindications to living kidney donation are now viewed as standard of care, while new tools identify novel risk markers that were unrecognized in past decades. Recent work suggests that nearly 10% of a cohort of patients with chronic/end stage kidney disease had an identifiable genetic etiology, many whose original cause of renal disease was either unknown or misdiagnosed. Some also had an incidentally found genetic variant, unrelated to their nephropathy, but medically actionable. These patterns illustrate the substantial potential for genetic testing to better guide the selection of living donors and recipients, but guidance on the proper application and interpretation of novel technologies is in its infancy. In this review, we examine the utility of genetic testing in various kidney conditions, discuss risks and unresolved challenges. Suggested algorithms in the context of related and unrelated donation are offered.
Summary: Genetic testing is a rapidly evolving strategy for the evaluation of candidates for living donor transplantation and their potential donors that has potential to improve risk assessment and optimize the safety of donation.
{"title":"Evaluation of Genetic Kidney Diseases in Living Donor Kidney Transplantation: Towards Precision Genomic Medicine in Donor Risk Assessment.","authors":"Yasar Caliskan, Brian Lee, Adrian Whelan, Fadee Abualrub, Krista L Lentine, Arksarapuk Jittirat","doi":"10.1007/s40472-021-00340-3","DOIUrl":"https://doi.org/10.1007/s40472-021-00340-3","url":null,"abstract":"<p><strong>Purpose of review: </strong>To provide a comprehensive update on the role of genetic testing for the evaluation of kidney transplant recipient and living donor candidates.</p><p><strong>Recent findings: </strong>The evaluation of candidates for living donor transplantation and their potential donors occur within an ever-changing landscape impacted by new evidence and risk assessment techniques. Criteria that were once considered contraindications to living kidney donation are now viewed as standard of care, while new tools identify novel risk markers that were unrecognized in past decades. Recent work suggests that nearly 10% of a cohort of patients with chronic/end stage kidney disease had an identifiable genetic etiology, many whose original cause of renal disease was either unknown or misdiagnosed. Some also had an incidentally found genetic variant, unrelated to their nephropathy, but medically actionable. These patterns illustrate the substantial potential for genetic testing to better guide the selection of living donors and recipients, but guidance on the proper application and interpretation of novel technologies is in its infancy. In this review, we examine the utility of genetic testing in various kidney conditions, discuss risks and unresolved challenges. Suggested algorithms in the context of related and unrelated donation are offered.</p><p><strong>Summary: </strong>Genetic testing is a rapidly evolving strategy for the evaluation of candidates for living donor transplantation and their potential donors that has potential to improve risk assessment and optimize the safety of donation.</p>","PeriodicalId":36387,"journal":{"name":"Current Transplantation Reports","volume":" ","pages":"127-142"},"PeriodicalIF":2.1,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236183/pdf/nihms-1770446.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40408073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-01DOI: 10.1007/s40472-021-00341-2
Samuel J. Gavzy, J. Scalea
{"title":"Organ Transportation Innovations and Future Trends","authors":"Samuel J. Gavzy, J. Scalea","doi":"10.1007/s40472-021-00341-2","DOIUrl":"https://doi.org/10.1007/s40472-021-00341-2","url":null,"abstract":"","PeriodicalId":36387,"journal":{"name":"Current Transplantation Reports","volume":"9 1","pages":"143-147"},"PeriodicalIF":2.1,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49104020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-28DOI: 10.1007/s40472-021-00338-x
Yee Lu, S. Norman, M. Doshi
{"title":"Understanding Structural Racism as a Barrier to Living Donor Kidney Transplantation and Transplant Care","authors":"Yee Lu, S. Norman, M. Doshi","doi":"10.1007/s40472-021-00338-x","DOIUrl":"https://doi.org/10.1007/s40472-021-00338-x","url":null,"abstract":"","PeriodicalId":36387,"journal":{"name":"Current Transplantation Reports","volume":"9 1","pages":"119-126"},"PeriodicalIF":2.1,"publicationDate":"2022-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49509348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-27DOI: 10.1007/s40472-022-00370-5
G. Hirdman, A. Niroomand, F. Olm, S. Lindstedt
{"title":"Correction to: Taking a Deep Breath: an Examination of Current Controversies in Surgical Procedures in Lung Transplantation","authors":"G. Hirdman, A. Niroomand, F. Olm, S. Lindstedt","doi":"10.1007/s40472-022-00370-5","DOIUrl":"https://doi.org/10.1007/s40472-022-00370-5","url":null,"abstract":"","PeriodicalId":36387,"journal":{"name":"Current Transplantation Reports","volume":"9 1","pages":"173 - 173"},"PeriodicalIF":2.1,"publicationDate":"2022-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48872234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-24DOI: 10.1007/s40472-022-00369-y
Irene K Kim, Paulo N. Martins, M. Pavlakis, N. Eneanya, R. Patzer
{"title":"Past and Present Policy Efforts in Achieving Racial Equity in Kidney Transplantation","authors":"Irene K Kim, Paulo N. Martins, M. Pavlakis, N. Eneanya, R. Patzer","doi":"10.1007/s40472-022-00369-y","DOIUrl":"https://doi.org/10.1007/s40472-022-00369-y","url":null,"abstract":"","PeriodicalId":36387,"journal":{"name":"Current Transplantation Reports","volume":"9 1","pages":"114 - 118"},"PeriodicalIF":2.1,"publicationDate":"2022-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44422641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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