Pub Date : 2025-11-19eCollection Date: 2025-10-01DOI: 10.2106/JBJS.OA.25.00145
Benjamin C Hawthorne, Lisa M Tamburini, Marissa A Gedman, Rohan R Patel, Tomer Korabelnikov, Michelle Ambrosio, Ian J Wellington, Matthew E Shuman, Scott Mallozzi, Hardeep Singh
Background: The public adoption of artificial intelligence (AI) tools such as ChatGPT has expanded rapidly in recent years, including growing use among healthcare professionals. The purpose of this study was to assess the use of AI and plagiarism in orthopaedic surgery residency applications across the 2022 to 2023, 2023 to 2024, and 2024 to 2025 application cycles.
Methods: Deidentified letters of recommendation (LORs) and personal statements (PSs) from interviewed applicants across 3 consecutive application cycles at a single institution were analyzed. Blinded reviewers input the documents into an online platform designed to detect AI-generated language and plagiarism.
Result: There was a statistically significant increase in the AI usage in LORs during the 2024 to 2025 application cycle (17.8%) compared with the 2023 to 2024 (5.0%) and 2022 to 2023 (5.6%) cycles (p < 0.001). Correspondingly, the originality scores of LORs significantly decreased in 2024 to 2025 (92.4%) compared with 2023 to 2024 (97.3%) and 2022 to 2023 (97.7%) (p < 0.001). By contrast, the AI usage in personal statements significantly decreased in 2024 to 2025 (43.5%) compared with 2023 to 2024 (60.3%) and 2022 to 2023 (65.2%) (p = 0.031). There was no significant difference in plagiarism scores across the 3 cycles for either LORs (p = 0.28) or PSs (p = 0.39).
Conclusions: The 2024 to 2025 application cycle showed a marked increase in AI usage in letters of recommendation, while the usage of AI in personal statements declined. These trends reflect evolving patterns in how applicants and letter writers are integrating AI tools into the application process.
Level of evidence: Level III; Retrospective Cohort Study. See Instructions for Authors for a complete description of levels of evidence.
{"title":"Trends in Artificial Intelligence Usage in Orthopaedic Surgery Residency Applications.","authors":"Benjamin C Hawthorne, Lisa M Tamburini, Marissa A Gedman, Rohan R Patel, Tomer Korabelnikov, Michelle Ambrosio, Ian J Wellington, Matthew E Shuman, Scott Mallozzi, Hardeep Singh","doi":"10.2106/JBJS.OA.25.00145","DOIUrl":"10.2106/JBJS.OA.25.00145","url":null,"abstract":"<p><strong>Background: </strong>The public adoption of artificial intelligence (AI) tools such as ChatGPT has expanded rapidly in recent years, including growing use among healthcare professionals. The purpose of this study was to assess the use of AI and plagiarism in orthopaedic surgery residency applications across the 2022 to 2023, 2023 to 2024, and 2024 to 2025 application cycles.</p><p><strong>Methods: </strong>Deidentified letters of recommendation (LORs) and personal statements (PSs) from interviewed applicants across 3 consecutive application cycles at a single institution were analyzed. Blinded reviewers input the documents into an online platform designed to detect AI-generated language and plagiarism.</p><p><strong>Result: </strong>There was a statistically significant increase in the AI usage in LORs during the 2024 to 2025 application cycle (17.8%) compared with the 2023 to 2024 (5.0%) and 2022 to 2023 (5.6%) cycles (p < 0.001). Correspondingly, the originality scores of LORs significantly decreased in 2024 to 2025 (92.4%) compared with 2023 to 2024 (97.3%) and 2022 to 2023 (97.7%) (p < 0.001). By contrast, the AI usage in personal statements significantly decreased in 2024 to 2025 (43.5%) compared with 2023 to 2024 (60.3%) and 2022 to 2023 (65.2%) (p = 0.031). There was no significant difference in plagiarism scores across the 3 cycles for either LORs (p = 0.28) or PSs (p = 0.39).</p><p><strong>Conclusions: </strong>The 2024 to 2025 application cycle showed a marked increase in AI usage in letters of recommendation, while the usage of AI in personal statements declined. These trends reflect evolving patterns in how applicants and letter writers are integrating AI tools into the application process.</p><p><strong>Level of evidence: </strong>Level III; Retrospective Cohort Study. See Instructions for Authors for a complete description of levels of evidence.</p>","PeriodicalId":36492,"journal":{"name":"JBJS Open Access","volume":"10 4","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12622691/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145557828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-19eCollection Date: 2025-10-01DOI: 10.2106/JBJS.OA.25.00148
Ophelie Lavoie-Gagne, Kelsey Brown, Alexander Kwon, Nishant Suneja, Michael J Weaver, George S Dyer, Mitchel B Harris, Bharti Khurana
<p><strong>Background: </strong>Intimate partner violence (IPV) commonly manifests as a musculoskeletal injury, yet the majority of orthopaedic surgeons estimate IPV to be rare in "their" orthopaedic patients. This work aimed to (1) provide education on the prevalence and manifestations of IPV, (2) investigate departmental referral patterns to Domestic Abuse Intervention Programs (DAIP) at 2 high-volume quaternary-academic centers, and (3) characterize IPV cases identified by orthopaedic surgery providers.</p><p><strong>Methods: </strong>The DAIP registry from 2000 to 2024 was queried for patients reporting IPV. Referrals were categorized by department and provider type. The electronic health record of patients referred by orthopaedics was further investigated for case characteristics. Findings were summarized as count/percentages and referral rates compared via the 2-proportion z-test with alpha set at 0.05.</p><p><strong>Results: </strong>A total of 11,227 patients were referred to DAIPs. The most common referrals were from the emergency department (ED) (29.3%; n = 2,393), behavioral health (18.2%; n = 2039), and obstetrics/gynecology (8.4%; n = 939), while only 0.3% (n = 30) patients were referred by orthopaedic surgery providers (p < 0.001). Patients referred by orthopaedics were commonly female (83.3%; n = 25) and identified during an inpatient encounter (76.7%; n = 23). Half (53.3%; n = 16) presented with an injury sustained from abuse, while the remaining patients presented for scheduled care. Injuries included high-energy injuries such as subtrochanteric, open tibia, bicondylar tibial plateau, and nongeriatric elbow fractures. Orthopaedic referrals to DAIPs relied on social workers (93.3%; n = 28). In the inpatient/ED setting, patients initially disclosed to bedside nurses (56.0%; n = 14), residents (20.0%; n = 5), and advanced practice providers (16.0%; n = 4), while patients disclosed to attendings (60%; n = 3) and fellows (40%; n = 2) in the outpatient setting. The majority (76.7%; n = 23) of patients reporting IPV-only interacted with orthopaedic providers in the 6 months preceding IPV disclosure. IPV identification led to patient safety coordination (16.7%; n = 5), alternative care plans (23.3%; n = 7), and resource assistance applications (23.3%; n = 7). Patients referred to DAIPs remained engaged in services a median 6.8 years after referral.</p><p><strong>Conclusions: </strong>Orthopaedic surgery referrals to DAIPs are significantly lower than other specialties, highlighting missed opportunities for intervention in both inpatient and outpatient contexts. Enhancing IPV awareness and screening in orthopaedics could improve patient safety and long-term support. Integration of artificial intelligence has the potential to facilitate efficient targeted screening within existing practice models.</p><p><strong>Level of evidence: </strong>Level III (retrospective cohort). See Instructions for Authors for a complete description of levels of
{"title":"Missed Opportunities in Orthopaedics for Intimate Partner Violence Identification: A Retrospective Review Over 24 years.","authors":"Ophelie Lavoie-Gagne, Kelsey Brown, Alexander Kwon, Nishant Suneja, Michael J Weaver, George S Dyer, Mitchel B Harris, Bharti Khurana","doi":"10.2106/JBJS.OA.25.00148","DOIUrl":"10.2106/JBJS.OA.25.00148","url":null,"abstract":"<p><strong>Background: </strong>Intimate partner violence (IPV) commonly manifests as a musculoskeletal injury, yet the majority of orthopaedic surgeons estimate IPV to be rare in \"their\" orthopaedic patients. This work aimed to (1) provide education on the prevalence and manifestations of IPV, (2) investigate departmental referral patterns to Domestic Abuse Intervention Programs (DAIP) at 2 high-volume quaternary-academic centers, and (3) characterize IPV cases identified by orthopaedic surgery providers.</p><p><strong>Methods: </strong>The DAIP registry from 2000 to 2024 was queried for patients reporting IPV. Referrals were categorized by department and provider type. The electronic health record of patients referred by orthopaedics was further investigated for case characteristics. Findings were summarized as count/percentages and referral rates compared via the 2-proportion z-test with alpha set at 0.05.</p><p><strong>Results: </strong>A total of 11,227 patients were referred to DAIPs. The most common referrals were from the emergency department (ED) (29.3%; n = 2,393), behavioral health (18.2%; n = 2039), and obstetrics/gynecology (8.4%; n = 939), while only 0.3% (n = 30) patients were referred by orthopaedic surgery providers (p < 0.001). Patients referred by orthopaedics were commonly female (83.3%; n = 25) and identified during an inpatient encounter (76.7%; n = 23). Half (53.3%; n = 16) presented with an injury sustained from abuse, while the remaining patients presented for scheduled care. Injuries included high-energy injuries such as subtrochanteric, open tibia, bicondylar tibial plateau, and nongeriatric elbow fractures. Orthopaedic referrals to DAIPs relied on social workers (93.3%; n = 28). In the inpatient/ED setting, patients initially disclosed to bedside nurses (56.0%; n = 14), residents (20.0%; n = 5), and advanced practice providers (16.0%; n = 4), while patients disclosed to attendings (60%; n = 3) and fellows (40%; n = 2) in the outpatient setting. The majority (76.7%; n = 23) of patients reporting IPV-only interacted with orthopaedic providers in the 6 months preceding IPV disclosure. IPV identification led to patient safety coordination (16.7%; n = 5), alternative care plans (23.3%; n = 7), and resource assistance applications (23.3%; n = 7). Patients referred to DAIPs remained engaged in services a median 6.8 years after referral.</p><p><strong>Conclusions: </strong>Orthopaedic surgery referrals to DAIPs are significantly lower than other specialties, highlighting missed opportunities for intervention in both inpatient and outpatient contexts. Enhancing IPV awareness and screening in orthopaedics could improve patient safety and long-term support. Integration of artificial intelligence has the potential to facilitate efficient targeted screening within existing practice models.</p><p><strong>Level of evidence: </strong>Level III (retrospective cohort). See Instructions for Authors for a complete description of levels of","PeriodicalId":36492,"journal":{"name":"JBJS Open Access","volume":"10 4","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12622684/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145557833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-19eCollection Date: 2025-10-01DOI: 10.2106/JBJS.OA.25.00228
Morgan G Batley, Joseph Yellin, J Todd Lawrence, Lawrence Wells, Brendan A Williams
Background: Currently, there is a dearth of literature regarding the indications for treatments of humeral head avascular necrosis (AVN) in the pediatric and young adult population and their long-term outcomes. The purpose of this study was to report on a consecutive series of patients treated at a single institution for humeral head AVN to describe diagnostic findings, implemented treatments, and long-term patient outcomes.
Methods: A retrospective review and cross-sectional outcomes assessment was performed to identify patients with humeral head AVN treated at a pediatric hospital between 2011 and 2021. Patient demographics, treatment strategies, and outcomes were retrospectively analyzed. A cross-sectional survey was then distributed that included patient-reported outcome measures and evaluated definitive shoulder treatment. Descriptive statistics were used to summarize patient characteristics and outcome scores.
Results: We identified 30 shoulders in 21 patients meeting study criteria. Patients were 16.9 years old at AVN diagnosis and predominantly male (12, 57%). Diagnosis was prompted by pain in most cases (20, 95%) and often associated with cancer treatment (12, 57%) or steroid use (10, 48%). Most shoulders were examined with magnetic resonance imaging (28, 93%) and identified as Stage II at diagnosis (19, 68%). Shoulders were usually nonoperatively treated initially. Eleven patients (52%) completed the cross-sectional outcomes assessment at an average of 7.13 years from diagnosis. Notably, 10 shoulders (55.6%) underwent operative treatment within this time course (28% underwent arthroplasty). Patient-Reported Outcome Measurement Information System and American Shoulder and Elbow Surgeons Evaluation score data showed scores within normative ranges for this population at follow-up.
Conclusion: This study expands on the limited literature regarding AVN of the humeral head in young patients. Patients were often treated nonoperatively through cross-sectional follow-up. Importantly, patients reported functionality and outcome scores within normative ranges. These results suggest nonoperative treatment is an effective initial management strategy for AVN of the humeral head in pediatric patients, but operative treatment may ultimately be required in a subset of patients. Further work is necessary to determine appropriate indications and timing of surgical treatment for this condition in this population.
Levels of evidence: Level III. See Instructions for Authors for a complete description of levels of evidence.
{"title":"Avascular Necrosis of the Humeral Head in Adolescents and Young Adults-Treatment and Long-Term Outcomes.","authors":"Morgan G Batley, Joseph Yellin, J Todd Lawrence, Lawrence Wells, Brendan A Williams","doi":"10.2106/JBJS.OA.25.00228","DOIUrl":"10.2106/JBJS.OA.25.00228","url":null,"abstract":"<p><strong>Background: </strong>Currently, there is a dearth of literature regarding the indications for treatments of humeral head avascular necrosis (AVN) in the pediatric and young adult population and their long-term outcomes. The purpose of this study was to report on a consecutive series of patients treated at a single institution for humeral head AVN to describe diagnostic findings, implemented treatments, and long-term patient outcomes.</p><p><strong>Methods: </strong>A retrospective review and cross-sectional outcomes assessment was performed to identify patients with humeral head AVN treated at a pediatric hospital between 2011 and 2021. Patient demographics, treatment strategies, and outcomes were retrospectively analyzed. A cross-sectional survey was then distributed that included patient-reported outcome measures and evaluated definitive shoulder treatment. Descriptive statistics were used to summarize patient characteristics and outcome scores.</p><p><strong>Results: </strong>We identified 30 shoulders in 21 patients meeting study criteria. Patients were 16.9 years old at AVN diagnosis and predominantly male (12, 57%). Diagnosis was prompted by pain in most cases (20, 95%) and often associated with cancer treatment (12, 57%) or steroid use (10, 48%). Most shoulders were examined with magnetic resonance imaging (28, 93%) and identified as Stage II at diagnosis (19, 68%). Shoulders were usually nonoperatively treated initially. Eleven patients (52%) completed the cross-sectional outcomes assessment at an average of 7.13 years from diagnosis. Notably, 10 shoulders (55.6%) underwent operative treatment within this time course (28% underwent arthroplasty). Patient-Reported Outcome Measurement Information System and American Shoulder and Elbow Surgeons Evaluation score data showed scores within normative ranges for this population at follow-up.</p><p><strong>Conclusion: </strong>This study expands on the limited literature regarding AVN of the humeral head in young patients. Patients were often treated nonoperatively through cross-sectional follow-up. Importantly, patients reported functionality and outcome scores within normative ranges. These results suggest nonoperative treatment is an effective initial management strategy for AVN of the humeral head in pediatric patients, but operative treatment may ultimately be required in a subset of patients. Further work is necessary to determine appropriate indications and timing of surgical treatment for this condition in this population.</p><p><strong>Levels of evidence: </strong>Level III. See Instructions for Authors for a complete description of levels of evidence.</p>","PeriodicalId":36492,"journal":{"name":"JBJS Open Access","volume":"10 4","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12622610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145557860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-19eCollection Date: 2025-10-01DOI: 10.2106/JBJS.OA.25.00256
Duco W P M Laane, Robert K Wagner, Thirushan Wignakumar, Robin Hu, Marco Tulio Di Stefano, Fatmanur Aydin, Annemarie van Rossum du Chattel, Marcos R González, Matthew Mariyampillai, Kihyun Kwon, Jacob Mandell, Detlef van der Velde, Michael J Weaver
Background: Geriatric hip fractures remain associated with significant mortality and morbidity. Identifying factors associated with such outcomes is an important step for improvement of prognostication and supporting individualized care. Sarcopenia is a known risk factor for mortality and thigh muscle measurements on plain radiographs can serve as a proxy measure of sarcopenia. Therefore, the objective was to determine whether radiographic thigh muscle measurements were independently associated with 1-year mortality following hip fracture surgery.
Methods: All consecutive patients aged 70 years or older undergoing operative treatment for an isolated hip fracture at 2 urban Level 1 trauma centers between 2018 and 2020 with preoperative radiographs displaying the distal-and-middle femur were included. Thigh muscle diameter and soft tissue size was measured on anteroposterior and lateral radiographs using standardized anatomical landmarks. Multivariable logistic regression was performed to determine if there were independent associations with 1-year mortality for the variables assessed. Inter-rater reliability for each measurement was evaluated by calculating intraclass correlation coefficients (ICCs).
Results: One hundred ninety-nine patients (median age 85 years, 68% female) were included. One-year mortality was 22%. After adjusting for age, sex, smoking status, preinjury living situation, Charlson Comorbidity Index, frailty, and body mass index, a greater thigh muscle diameter on anteroposterior radiographs was associated with lower odds of 1-year mortality (adjusted odds ratio 0.74, 95% confidence interval 0.56-0.97, p = 0.028). There was no significant association with thigh muscle diameter on lateral radiographs or with total soft tissue diameter on anteroposterior or lateral radiographs. The ICCs demonstrated good-to-excellent reliability for all radiographic measurements.
Conclusion: Greater thigh muscle diameter measured on anteroposterior radiographs was independently associated with decreased 1-year mortality following hip fracture surgery, with each centimeter increase in diameter being associated with an average reduction in odds of 26%. This finding should be interpreted in the context of the limited sample size, homogenous patient population, and range of observed thigh muscle sizes. Overall, these results suggest that radiographic parameters may potentially serve to complement currently used modalities, such as frailty assessment, in supporting individualized care.
Level of evidence: Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
{"title":"Radiographic Thigh Muscle Measurements Are Independently Associated with 1-Year Mortality Following Hip Fracture Surgery.","authors":"Duco W P M Laane, Robert K Wagner, Thirushan Wignakumar, Robin Hu, Marco Tulio Di Stefano, Fatmanur Aydin, Annemarie van Rossum du Chattel, Marcos R González, Matthew Mariyampillai, Kihyun Kwon, Jacob Mandell, Detlef van der Velde, Michael J Weaver","doi":"10.2106/JBJS.OA.25.00256","DOIUrl":"10.2106/JBJS.OA.25.00256","url":null,"abstract":"<p><strong>Background: </strong>Geriatric hip fractures remain associated with significant mortality and morbidity. Identifying factors associated with such outcomes is an important step for improvement of prognostication and supporting individualized care. Sarcopenia is a known risk factor for mortality and thigh muscle measurements on plain radiographs can serve as a proxy measure of sarcopenia. Therefore, the objective was to determine whether radiographic thigh muscle measurements were independently associated with 1-year mortality following hip fracture surgery.</p><p><strong>Methods: </strong>All consecutive patients aged 70 years or older undergoing operative treatment for an isolated hip fracture at 2 urban Level 1 trauma centers between 2018 and 2020 with preoperative radiographs displaying the distal-and-middle femur were included. Thigh muscle diameter and soft tissue size was measured on anteroposterior and lateral radiographs using standardized anatomical landmarks. Multivariable logistic regression was performed to determine if there were independent associations with 1-year mortality for the variables assessed. Inter-rater reliability for each measurement was evaluated by calculating intraclass correlation coefficients (ICCs).</p><p><strong>Results: </strong>One hundred ninety-nine patients (median age 85 years, 68% female) were included. One-year mortality was 22%. After adjusting for age, sex, smoking status, preinjury living situation, Charlson Comorbidity Index, frailty, and body mass index, a greater thigh muscle diameter on anteroposterior radiographs was associated with lower odds of 1-year mortality (adjusted odds ratio 0.74, 95% confidence interval 0.56-0.97, p = 0.028). There was no significant association with thigh muscle diameter on lateral radiographs or with total soft tissue diameter on anteroposterior or lateral radiographs. The ICCs demonstrated good-to-excellent reliability for all radiographic measurements.</p><p><strong>Conclusion: </strong>Greater thigh muscle diameter measured on anteroposterior radiographs was independently associated with decreased 1-year mortality following hip fracture surgery, with each centimeter increase in diameter being associated with an average reduction in odds of 26%. This finding should be interpreted in the context of the limited sample size, homogenous patient population, and range of observed thigh muscle sizes. Overall, these results suggest that radiographic parameters may potentially serve to complement currently used modalities, such as frailty assessment, in supporting individualized care.</p><p><strong>Level of evidence: </strong>Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.</p>","PeriodicalId":36492,"journal":{"name":"JBJS Open Access","volume":"10 4","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12622681/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145557810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-14eCollection Date: 2025-10-01DOI: 10.2106/JBJS.OA.25.00231
Mark T Dahl, Elizabeth P Wellings, Cole Funk, Andrew G Georgiadis
Background: Acquired and congenital limb length discrepancies often coexist with deformities of the distal femur. Lengthening of the femur along its anatomic axis changes the limb's mechanical alignment. Angular correction and lengthening can be achieved at the same site if a retrograde lengthening nail is used with a specific preoperative planning method ("reverse planning") which permits patient-specific selection of the final mechanical axis.
Methods: A consecutive cohort series of children, adolescents, and young adults (mean 15.6 ± 4.8 years) undergoing retrograde implantable femoral lengthening between the years 2011 and 2024 were analyzed. Surgical details, lengthening parameters, Limb Lengthening and Reconstruction Society (LLRS)-AIM index, accuracy of final correction, and complications were reviewed and classified. Patients were eligible only if the distal femoral physis was closed.
Results: Seventy-three lengthening were eligible in the study period. Average lengthening was 4.2 ± 1.4 cm (range 2.0-8.0 cm), and consolidation index was 39.4 ± 21.9 days/cm. Deformities and length discrepancies were moderately complex, with a mean LLRS AIM score of 6 (range 1-13). Complication rates were similar to previous reports of intramedullary femoral lengthening, comparable between congenital (12 of 31, 39%) and acquired etiologies (16 of 42, 38%). Preoperative coronal alignment ranged from 14° varus to 20° valgus, while final coronal alignment was 0.4° ± 3.4° of neutral (range 7° valgus to 13° varus). Coronal deformities up to 20° and sagittal deformities up to 23° were corrected acutely at the lengthening site.
Conclusions: Retrograde intramedullary femoral lengthening with acute deformity correction at the same site is an alternative to antegrade lengthening with separate osteotomy of the distal femur in children and adolescents. The reverse planning method allows reproducible length and deformity correction at the same location. Specific intraoperative technical adjuncts are used to achieve and maintain the desired alignment.
Level of evidence: Diagnostic Level IV. See Instructions for Authors for a complete description of levels of evidence.
{"title":"Retrograde Intramedullary Femoral Lengthening With Acute Deformity Correction in Children, Adolescents, and Young Adults.","authors":"Mark T Dahl, Elizabeth P Wellings, Cole Funk, Andrew G Georgiadis","doi":"10.2106/JBJS.OA.25.00231","DOIUrl":"10.2106/JBJS.OA.25.00231","url":null,"abstract":"<p><strong>Background: </strong>Acquired and congenital limb length discrepancies often coexist with deformities of the distal femur. Lengthening of the femur along its anatomic axis changes the limb's mechanical alignment. Angular correction and lengthening can be achieved at the same site if a retrograde lengthening nail is used with a specific preoperative planning method (\"reverse planning\") which permits patient-specific selection of the final mechanical axis.</p><p><strong>Methods: </strong>A consecutive cohort series of children, adolescents, and young adults (mean 15.6 ± 4.8 years) undergoing retrograde implantable femoral lengthening between the years 2011 and 2024 were analyzed. Surgical details, lengthening parameters, Limb Lengthening and Reconstruction Society (LLRS)-AIM index, accuracy of final correction, and complications were reviewed and classified. Patients were eligible only if the distal femoral physis was closed.</p><p><strong>Results: </strong>Seventy-three lengthening were eligible in the study period. Average lengthening was 4.2 ± 1.4 cm (range 2.0-8.0 cm), and consolidation index was 39.4 ± 21.9 days/cm. Deformities and length discrepancies were moderately complex, with a mean LLRS AIM score of 6 (range 1-13). Complication rates were similar to previous reports of intramedullary femoral lengthening, comparable between congenital (12 of 31, 39%) and acquired etiologies (16 of 42, 38%). Preoperative coronal alignment ranged from 14° varus to 20° valgus, while final coronal alignment was 0.4° ± 3.4° of neutral (range 7° valgus to 13° varus). Coronal deformities up to 20° and sagittal deformities up to 23° were corrected acutely at the lengthening site.</p><p><strong>Conclusions: </strong>Retrograde intramedullary femoral lengthening with acute deformity correction at the same site is an alternative to antegrade lengthening with separate osteotomy of the distal femur in children and adolescents. The reverse planning method allows reproducible length and deformity correction at the same location. Specific intraoperative technical adjuncts are used to achieve and maintain the desired alignment.</p><p><strong>Level of evidence: </strong>Diagnostic Level IV. See Instructions for Authors for a complete description of levels of evidence.</p>","PeriodicalId":36492,"journal":{"name":"JBJS Open Access","volume":"10 4","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12599768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145496795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-14eCollection Date: 2025-10-01DOI: 10.2106/JBJS.OA.25.00159
Zhuoyu Li, Weifeng Liu, Tao Jin, Yang Sun, Yuan Li, Xiaohui Niu, Chunyan Jiang, Qing Zhang
Background: The aim of this study was to investigate the clinical outcomes and complications of vascularized fibular epiphyseal transfer (VFET) and clavicle pro humero (CPH) for proximal humeral reconstruction after primary sarcoma resection in skeletally immature patients.
Patients and methods: This retrospective case-control study included 29 skeletally immature patients (18 male patients, 11 female patients) with primary bone sarcomas who were treated between January 2009 and June 2023 at Beijing Jishuitan Hospital. The average age was 9.4 ± 2.8 years (range, 5-14), and the pathological type included osteosarcoma (25) and Ewing sarcoma (4). We compared the graft survival, function, and complication rate between the VFET group and the CPH group.
Results: The 2-year and 5-year overall survival rates for the VFET group and CPH group were 94%, 75%, 86%, and 55%, respectively. The 2-year and 5-year revision-free survival for the VFET group and CPH group were 77%, 61%, 75%, and 37%, respectively. At the final follow-up, the mean MSTS-93 score in the VFET group was 82% (67%-97%), while the mean MSTS-93 score in the CPH group was 79% (73%-96%, p > 0.05). The incidence of mechanical complications was significantly higher in the CPH group (88%, 7/8) than that in the VFET group (52%, 11/21) (p = 0.036). The mean difference in upper limb length in the VFET group was 5.0 ± 2.9 cm and 10.2 ± 4.2 cm in the CPH group (p = 0.003).
Conclusions: We suggest that vascularized fibular epiphyseal transfer may be considered as a promising biological reconstruction option for pediatric patients with proximal humeral osteosarcoma who have a longer life expectancy. For institutions lacking the necessary microsurgical techniques, clavicle pro humero reconstruction remains a relatively simple and feasible alternative reconstruction option.
Level of evidence: Level III Case-control study. See Instructions for Authors for a complete description of levels of evidence.
{"title":"Comparison of Biological Reconstruction After Resection of Proximal Humerus Bone Sarcomas in Pediatric Patients.","authors":"Zhuoyu Li, Weifeng Liu, Tao Jin, Yang Sun, Yuan Li, Xiaohui Niu, Chunyan Jiang, Qing Zhang","doi":"10.2106/JBJS.OA.25.00159","DOIUrl":"10.2106/JBJS.OA.25.00159","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to investigate the clinical outcomes and complications of vascularized fibular epiphyseal transfer (VFET) and clavicle pro humero (CPH) for proximal humeral reconstruction after primary sarcoma resection in skeletally immature patients.</p><p><strong>Patients and methods: </strong>This retrospective case-control study included 29 skeletally immature patients (18 male patients, 11 female patients) with primary bone sarcomas who were treated between January 2009 and June 2023 at Beijing Jishuitan Hospital. The average age was 9.4 ± 2.8 years (range, 5-14), and the pathological type included osteosarcoma (25) and Ewing sarcoma (4). We compared the graft survival, function, and complication rate between the VFET group and the CPH group.</p><p><strong>Results: </strong>The 2-year and 5-year overall survival rates for the VFET group and CPH group were 94%, 75%, 86%, and 55%, respectively. The 2-year and 5-year revision-free survival for the VFET group and CPH group were 77%, 61%, 75%, and 37%, respectively. At the final follow-up, the mean MSTS-93 score in the VFET group was 82% (67%-97%), while the mean MSTS-93 score in the CPH group was 79% (73%-96%, p > 0.05). The incidence of mechanical complications was significantly higher in the CPH group (88%, 7/8) than that in the VFET group (52%, 11/21) (p = 0.036). The mean difference in upper limb length in the VFET group was 5.0 ± 2.9 cm and 10.2 ± 4.2 cm in the CPH group (p = 0.003).</p><p><strong>Conclusions: </strong>We suggest that vascularized fibular epiphyseal transfer may be considered as a promising biological reconstruction option for pediatric patients with proximal humeral osteosarcoma who have a longer life expectancy. For institutions lacking the necessary microsurgical techniques, clavicle pro humero reconstruction remains a relatively simple and feasible alternative reconstruction option.</p><p><strong>Level of evidence: </strong>Level III Case-control study. See Instructions for Authors for a complete description of levels of evidence.</p>","PeriodicalId":36492,"journal":{"name":"JBJS Open Access","volume":"10 4","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12599762/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145496817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-14eCollection Date: 2025-10-01DOI: 10.2106/JBJS.OA.25.00141
Carlos Suarez-Ahedo, Miguel Alejandro Quintero-Quintero, Carlos Martinez-Armenta, Laura E Martínez-Gómez, Gabriela A Martínez-Nava, Carlos Pineda, Alberto López-Reyes
» Dual mobility cup (DMC) implants reduce dislocation rates in both primary and revision total hip arthroplasty (THA), particularly in high-risk patients with neuromuscular disorders, cognitive impairment, or obesity. » The dual articulation mechanism enhances joint stability by increasing jump distance and the head-to-neck ratio, without compromising range of motion. » Incorporation of highly cross-linked polyethylene and vitamin E-infused liners improves wear resistance, supporting broader use in younger, more active patients. » Long-term survivorship of modern DMCs is comparable or superior to fixed-bearing implants, with a lower revision burden and durable fixation when appropriately selected and implanted. » Systemic metal ion levels remain low in well-functioning modular DMCs, though continued monitoring is recommended in younger patients and those with reproductive potential.
{"title":"Modern Dual Mobility Implants in Total Hip Arthroplasty: Stability, Survival, and Ion Safety Evaluation: The Comprehensive Review.","authors":"Carlos Suarez-Ahedo, Miguel Alejandro Quintero-Quintero, Carlos Martinez-Armenta, Laura E Martínez-Gómez, Gabriela A Martínez-Nava, Carlos Pineda, Alberto López-Reyes","doi":"10.2106/JBJS.OA.25.00141","DOIUrl":"10.2106/JBJS.OA.25.00141","url":null,"abstract":"<p><p>» Dual mobility cup (DMC) implants reduce dislocation rates in both primary and revision total hip arthroplasty (THA), particularly in high-risk patients with neuromuscular disorders, cognitive impairment, or obesity. » The dual articulation mechanism enhances joint stability by increasing jump distance and the head-to-neck ratio, without compromising range of motion. » Incorporation of highly cross-linked polyethylene and vitamin E-infused liners improves wear resistance, supporting broader use in younger, more active patients. » Long-term survivorship of modern DMCs is comparable or superior to fixed-bearing implants, with a lower revision burden and durable fixation when appropriately selected and implanted. » Systemic metal ion levels remain low in well-functioning modular DMCs, though continued monitoring is recommended in younger patients and those with reproductive potential.</p>","PeriodicalId":36492,"journal":{"name":"JBJS Open Access","volume":"10 4","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12599780/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145496857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: As the global population ages, an increasing number of older individuals reside in nursing homes, underscoring the need to include this group in discharge outcome analyses. The aim of this study was to assess the effect of early surgical intervention (defined as surgery within 48 hours of injury) on ambulatory function at discharge and the likelihood of returning to the preinjury residence, including discharge to nursing homes, among patients with hip fractures.
Methods: We retrospectively analyzed 455 patients who underwent open reduction and internal fixation (ORIF) for hip fractures at our institution between April 2017 and March 2023. Patients were categorized into 2 groups based on the timing of surgery: the "early group" (within 48 hours) and the "delayed group" (after 48 hours).
Results: The early group included 338 patients, while the delayed group included 117 patients. The mean functional independence measure (FIM) (locomotion) score at discharge was 5.35 in the early group and 4.68 in the delayed group (p = 0.04). Spearman correlation coefficient between early surgical intervention and FIM (locomotion) at discharge was 0.097 (p < 0.05). Multiple regression analysis revealed a regression coefficient of 0.63 (p = 0.02) for early surgical intervention with respect to FIM (locomotion) at discharge. Furthermore, logistic regression analysis indicated that the higher FIM (locomotion) score at discharge was associated with an increased likelihood of returning to the preinjury residence (regression coefficient = 0.30, p < 0.001).
Conclusions: Early surgical intervention was associated with improved FIM (locomotion) scores at discharge. Higher FIM (locomotion) scores at discharge were correlated with an increased likelihood of returning to the preinjury residence. These findings underscore the importance of early functional recovery in older patients undergoing ORIF for hip fractures, as surgical delays can hinder the restoration of activities of daily living. Therefore, where feasible, early ORIF should be prioritized to optimize patient outcomes.
Level of evidence: Diagnostic Level III. See Instructions for Authors for a complete description of levels of evidence.
{"title":"Early Surgical Intervention Enhances Ambulatory Function at Discharge and Increases the Likelihood of Returning to Preinjury Residence in Older Patients With Hip Fractures.","authors":"Hirotaka Kawakami, Hiromi Sasaki, Junichi Kamizono, Yusuke Fujimoto, Noboru Taniguchi","doi":"10.2106/JBJS.OA.25.00122","DOIUrl":"10.2106/JBJS.OA.25.00122","url":null,"abstract":"<p><strong>Background: </strong>As the global population ages, an increasing number of older individuals reside in nursing homes, underscoring the need to include this group in discharge outcome analyses. The aim of this study was to assess the effect of early surgical intervention (defined as surgery within 48 hours of injury) on ambulatory function at discharge and the likelihood of returning to the preinjury residence, including discharge to nursing homes, among patients with hip fractures.</p><p><strong>Methods: </strong>We retrospectively analyzed 455 patients who underwent open reduction and internal fixation (ORIF) for hip fractures at our institution between April 2017 and March 2023. Patients were categorized into 2 groups based on the timing of surgery: the \"early group\" (within 48 hours) and the \"delayed group\" (after 48 hours).</p><p><strong>Results: </strong>The early group included 338 patients, while the delayed group included 117 patients. The mean functional independence measure (FIM) (locomotion) score at discharge was 5.35 in the early group and 4.68 in the delayed group (p = 0.04). Spearman correlation coefficient between early surgical intervention and FIM (locomotion) at discharge was 0.097 (p < 0.05). Multiple regression analysis revealed a regression coefficient of 0.63 (p = 0.02) for early surgical intervention with respect to FIM (locomotion) at discharge. Furthermore, logistic regression analysis indicated that the higher FIM (locomotion) score at discharge was associated with an increased likelihood of returning to the preinjury residence (regression coefficient = 0.30, p < 0.001).</p><p><strong>Conclusions: </strong>Early surgical intervention was associated with improved FIM (locomotion) scores at discharge. Higher FIM (locomotion) scores at discharge were correlated with an increased likelihood of returning to the preinjury residence. These findings underscore the importance of early functional recovery in older patients undergoing ORIF for hip fractures, as surgical delays can hinder the restoration of activities of daily living. Therefore, where feasible, early ORIF should be prioritized to optimize patient outcomes.</p><p><strong>Level of evidence: </strong>Diagnostic Level III. See Instructions for Authors for a complete description of levels of evidence.</p>","PeriodicalId":36492,"journal":{"name":"JBJS Open Access","volume":"10 4","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12599772/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145496797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: We aimed to identify a new biomarker using 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT) parameters to identify osteosarcoma patients with standard response after neoadjuvant chemotherapy (NAC).
Patients and materials: Fifty-four patients with conventional osteosarcoma (age ≤39 years) were included in this study. All patients underwent 18F-FDG PET/CT before (PET1) and after NAC (PET2). We measured PET parameters, including maximum, average, and peak standardized uptake value (SUVmax, SUVave, and SUVpeak); metabolic tumor volume (MTV); and total lesion glycolysis (TLG). Their changes (ΔPET = PET2/PET1) were also examined. The patients were classified into 4 groups based on the histological tumor necrosis rate (TNR): G0 (<50%), G1 (50 to < 90%), G2 (90 to < 100%), and G3 (100%). G0 and G1 patients were enrolled in the standard responder (SR) group (n = 35), while G2 and G3 patients were enrolled in the good responder (GR) group (n = 19). We examined the correlation between changes in each 18F-FDG PET/CT parameter and TNR as well as overall survival (OS) and progression-free survival (PFS) among the 4 groups. In the SR group, the median value of ΔSUVmax was calculated and correlated with prognostic stratification.
Results: The changes in each PET parameter were correlated with TNR, with SUVpeak showing the strongest correlation. Moreover, in the SR group, there were no differences in OS or PFS between G0 and G1. Patients in the SR group were stratified into 2 groups according to the median ΔSUVmax value (0.62). Patients with ΔSUVmax < 0.62 had significantly better OS (P < 0.01) and PFS (P = 0.02) in comparison with patients with ΔSUVmax ≥ 0.62. In multivariate analyses, ΔSUVmax showed a correlation with OS in the SR group.
Discussion: This study revealed that ΔSUVmax may confirm the preoperative stratification of the prognosis be a predictive biomarker for patients in the SR group. Moreover, the preoperative identification of patients with a worse prognosis in the SR group has a significant impact on improving the clinical outcomes of patients with osteosarcoma.
Level of evidence: Prognostic studies, Level III. See Instructions for Authors for a complete description of levels of evidence.
{"title":"Prognostic Stratification of Standard Responders to Neoadjuvant Chemotherapy in Patients with Osteosarcoma Using <sup>18</sup>F-FDG PET/CT Imaging.","authors":"Toshiyuki Takemori, Eisuke Kobayashi, Akihiko Yoshida, Ayumu Arakawa, Hiroya Kondo, Satoshi Kamio, Seiji Shimomura, Shuhei Osaki, Koichi Ogura, Shintaro Iwata, Chitose Ogawa, Akira Kawai, Kimiteru Ito","doi":"10.2106/JBJS.OA.25.00133","DOIUrl":"10.2106/JBJS.OA.25.00133","url":null,"abstract":"<p><strong>Introduction: </strong>We aimed to identify a new biomarker using <sup>18</sup>F-fluorodeoxyglucose (<sup>18</sup>F-FDG) positron emission tomography (PET)/computed tomography (CT) parameters to identify osteosarcoma patients with standard response after neoadjuvant chemotherapy (NAC).</p><p><strong>Patients and materials: </strong>Fifty-four patients with conventional osteosarcoma (age ≤39 years) were included in this study. All patients underwent <sup>18</sup>F-FDG PET/CT before (PET1) and after NAC (PET2). We measured PET parameters, including maximum, average, and peak standardized uptake value (SUVmax, SUVave, and SUVpeak); metabolic tumor volume (MTV); and total lesion glycolysis (TLG). Their changes (ΔPET = PET2/PET1) were also examined. The patients were classified into 4 groups based on the histological tumor necrosis rate (TNR): G0 (<50%), G1 (50 to < 90%), G2 (90 to < 100%), and G3 (100%). G0 and G1 patients were enrolled in the standard responder (SR) group (n = 35), while G2 and G3 patients were enrolled in the good responder (GR) group (n = 19). We examined the correlation between changes in each <sup>18</sup>F-FDG PET/CT parameter and TNR as well as overall survival (OS) and progression-free survival (PFS) among the 4 groups. In the SR group, the median value of ΔSUVmax was calculated and correlated with prognostic stratification.</p><p><strong>Results: </strong>The changes in each PET parameter were correlated with TNR, with SUVpeak showing the strongest correlation. Moreover, in the SR group, there were no differences in OS or PFS between G0 and G1. Patients in the SR group were stratified into 2 groups according to the median ΔSUVmax value (0.62). Patients with ΔSUVmax < 0.62 had significantly better OS (P < 0.01) and PFS (P = 0.02) in comparison with patients with ΔSUVmax ≥ 0.62. In multivariate analyses, ΔSUVmax showed a correlation with OS in the SR group.</p><p><strong>Discussion: </strong>This study revealed that ΔSUVmax may confirm the preoperative stratification of the prognosis be a predictive biomarker for patients in the SR group. Moreover, the preoperative identification of patients with a worse prognosis in the SR group has a significant impact on improving the clinical outcomes of patients with osteosarcoma.</p><p><strong>Level of evidence: </strong>Prognostic studies, Level III. See Instructions for Authors for a complete description of levels of evidence.</p>","PeriodicalId":36492,"journal":{"name":"JBJS Open Access","volume":"10 4","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12599647/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145496846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-12eCollection Date: 2025-10-01DOI: 10.2106/JBJS.OA.25.00236
Tara Korbal, Kerr Graham, Sharmala Thuraisingam, Jason J Howard, Erich Rutz
Background: Musculoskeletal pathology (MSP) develops in the lower limbs of the majority of children with cerebral palsy (CP) with time and growth. The aims of this study were to investigate the epidemiology of MSP in the lower limbs, of a large population-based sample of children with CP, at long-term follow up.
Methods: An inception cohort was generated from the Victorian Cerebral Palsy Register for the birth years 1990 through 1992 inclusive. Children had regular clinical and radiographic examinations from infancy until after skeletal maturity. Cerebral palsy was classified using the Gross Motor Function Classification System (GMFCS) and a Topographical Classification System (TCS), devised for this study. MSP was classified using the Musculoskeletal Pathology Classification System, which has good reliability.
Results: A full dataset was available for 292 individuals, 78% of the inception cohort (170 males, 122 females). Mean age at final follow-up was 20 years (SD 4.5, range 6-31 years). MSP type changed with age. Hypertonia (MSP 1) was present in 77% of children at age 5 years, contractures (MSP 2) in 22% of children at 10 years, contractures combined with bony torsion (MSP 3) in 31% of teenagers at age 15 years, and decompensation (MSP 4) in 15% of young adults at age 25 years. There were moderate to strong associations between GMFCS and MSP and TCS and MSP (Kendall's tau 0.36-0.55, p < 0.001).
Conclusions: The prevalence of MSP in children with CP who were born between 1990 and 1992 and followed into the third decade was high and was related to age and CP severity by GMFCS.
Level of evidence: Level IV. See Instructions for Authors for a complete description of levels of evidence.
背景:大多数脑瘫(CP)患儿下肢肌肉骨骼病变(MSP)随着时间和生长而发展。本研究的目的是在长期随访中调查大量以人群为基础的CP患儿下肢MSP的流行病学。方法:从维多利亚州脑瘫登记中提取出生年份为1990年至1992年的初始队列。儿童从婴儿期到骨骼成熟后定期进行临床和影像学检查。脑性麻痹采用大运动功能分类系统(GMFCS)和地形分类系统(TCS)进行分类。MSP采用肌肉骨骼病理分类系统进行分类,具有良好的可靠性。结果:292人的完整数据集可用,占初始队列的78%(170名男性,122名女性)。最后随访时的平均年龄为20岁(SD 4.5,范围6-31岁)。MSP类型随年龄变化。5岁时77%的儿童出现高张力(msp1), 10岁时22%的儿童出现挛缩(msp2), 15岁时31%的青少年出现挛缩合并骨扭转(msp3), 25岁时15%的年轻人出现失代偿(msp4)。GMFCS与MSP、TCS与MSP之间存在中强相关性(Kendall’s tau 0.36 ~ 0.55, p < 0.001)。结论:1990 ~ 1992年出生并随访至第三十年的CP患儿MSP患病率较高,且与GMFCS测定的年龄和CP严重程度相关。证据等级:IV级。参见《作者说明》获得证据等级的完整描述。
{"title":"Epidemiology of Lower Limb Musculoskeletal Pathology in Cerebral Palsy: A Population-Based, Cohort Study.","authors":"Tara Korbal, Kerr Graham, Sharmala Thuraisingam, Jason J Howard, Erich Rutz","doi":"10.2106/JBJS.OA.25.00236","DOIUrl":"10.2106/JBJS.OA.25.00236","url":null,"abstract":"<p><strong>Background: </strong>Musculoskeletal pathology (MSP) develops in the lower limbs of the majority of children with cerebral palsy (CP) with time and growth. The aims of this study were to investigate the epidemiology of MSP in the lower limbs, of a large population-based sample of children with CP, at long-term follow up.</p><p><strong>Methods: </strong>An inception cohort was generated from the Victorian Cerebral Palsy Register for the birth years 1990 through 1992 inclusive. Children had regular clinical and radiographic examinations from infancy until after skeletal maturity. Cerebral palsy was classified using the Gross Motor Function Classification System (GMFCS) and a Topographical Classification System (TCS), devised for this study. MSP was classified using the Musculoskeletal Pathology Classification System, which has good reliability.</p><p><strong>Results: </strong>A full dataset was available for 292 individuals, 78% of the inception cohort (170 males, 122 females). Mean age at final follow-up was 20 years (SD 4.5, range 6-31 years). MSP type changed with age. Hypertonia (MSP 1) was present in 77% of children at age 5 years, contractures (MSP 2) in 22% of children at 10 years, contractures combined with bony torsion (MSP 3) in 31% of teenagers at age 15 years, and decompensation (MSP 4) in 15% of young adults at age 25 years. There were moderate to strong associations between GMFCS and MSP and TCS and MSP (Kendall's tau 0.36-0.55, p < 0.001).</p><p><strong>Conclusions: </strong>The prevalence of MSP in children with CP who were born between 1990 and 1992 and followed into the third decade was high and was related to age and CP severity by GMFCS.</p><p><strong>Level of evidence: </strong>Level IV. See Instructions for Authors for a complete description of levels of evidence.</p>","PeriodicalId":36492,"journal":{"name":"JBJS Open Access","volume":"10 4","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12594293/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145483142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}