Pub Date : 2024-02-16DOI: 10.29011/2577-2236.100182
{"title":"Radiofrequency in Cosmetic Gynecology, Literature Review 2018-2023","authors":"","doi":"10.29011/2577-2236.100182","DOIUrl":"https://doi.org/10.29011/2577-2236.100182","url":null,"abstract":"","PeriodicalId":365505,"journal":{"name":"Obstetrics & Gynecology: Open Access","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139960733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-15DOI: 10.29011/2577-2236.100178
{"title":"Unilateral Sacrospinous Ligament Fixation for the Treatment of Stage 3-4 Utero-Vaginal Prolapse: Single-Centre Experiences","authors":"","doi":"10.29011/2577-2236.100178","DOIUrl":"https://doi.org/10.29011/2577-2236.100178","url":null,"abstract":"","PeriodicalId":365505,"journal":{"name":"Obstetrics & Gynecology: Open Access","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139529770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-05DOI: 10.29011/2577-2236.100176
{"title":"Ovarian Neoplasm Versus Ovarian Lymphoma: A Literature Review with Focus on Radiology and Pathology Features","authors":"","doi":"10.29011/2577-2236.100176","DOIUrl":"https://doi.org/10.29011/2577-2236.100176","url":null,"abstract":"","PeriodicalId":365505,"journal":{"name":"Obstetrics & Gynecology: Open Access","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139381290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-05DOI: 10.29011/2577-2236.100177
{"title":"Concentrated Gelatinized Proprietary Phenotype Formulation of Lepidium peruvianum (maca) Positively Impacts Polycystic Ovarian Syndrome (PCOS), Premenstrual Syndrome (PMS), Dysmenorrhea, and Hormone Levels for Fertility Optimization: A Case Report","authors":"","doi":"10.29011/2577-2236.100177","DOIUrl":"https://doi.org/10.29011/2577-2236.100177","url":null,"abstract":"","PeriodicalId":365505,"journal":{"name":"Obstetrics & Gynecology: Open Access","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139535836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-29DOI: 10.29011/2577-2236.100175
{"title":"Endosalpingiosis in Pelvic Lymph Node with Atypical Endometrial Hyperplasia","authors":"","doi":"10.29011/2577-2236.100175","DOIUrl":"https://doi.org/10.29011/2577-2236.100175","url":null,"abstract":"","PeriodicalId":365505,"journal":{"name":"Obstetrics & Gynecology: Open Access","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139146671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-18DOI: 10.29011/2577-2236.100174
{"title":"Rigenase® and Polyhexanide Combination in a Hydrogel Formulation for the Treatment of Vaginosis Symptoms: The PMCF Survey","authors":"","doi":"10.29011/2577-2236.100174","DOIUrl":"https://doi.org/10.29011/2577-2236.100174","url":null,"abstract":"","PeriodicalId":365505,"journal":{"name":"Obstetrics & Gynecology: Open Access","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139175460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-03DOI: 10.29011/2577-2236.100165
Nc Obi, C. Oguejiofor, O. Okafor, G. Eleje, CG Okafor, JC Nkesi, Co Ezeigwe, MC Egbuniwe, BU Odugu, SO Nweze, EA Emeka, C. Ofiaeli, NL Onah, VV Okon, IJ Onyekpa, K. Obioha, B. Okpala, TB Ejikeme, CM Anyaoku, E. Egwuatu, O. Nnabuchi, C. Okeke, SC Egbogu, TN Agbo, OD Ugwu, OC Ekwebene
Background: Obstetric emergencies like eclampsia continue to be a leading cause of morbidity and mortality in pregnant women and fetuses in modern society. Given its detrimental consequences on the pregnant woman, her unborn child, and any later medical difficulties linked to this illness, it has remained to be a cause of concern for obstetricians, especially in low-and middle-income countries. Hence the requirement for periodic review in our environment. Objectives: The objective of this study is to determine the prevalence, pattern of presentation as well as fetal and maternal outcome of cases of eclampsia with a view to suggest interventions to reduce the incidence and associated morbidity and mortality associated with eclampsia. Materials and Methods: This study examines all eclampsia cases treated at Nnamdi Azikiwe University Teaching Hospital (NAUTH), Nnewi, Nigeria between January 1, 2017, and December 31, 2021. The hospital’s medical records division provided access to the case notes of every eclampsia patient. The socio-demographic and clinical data of the subjects were gathered using a systematic proforma, and they were then evaluated and analysed. The teaching hospital’s ethics committee was contacted in order to request and get ethical clearance and permission. The statistical software for social sciences (SPSS) version 25 was used to analyse the data. Results: The eclampsia prevalence rate observed was 1.65%. The ages of the women ranged from 18 to 41 years with mean age and standard deviation given as 26.97 ± 4.61 years. The majority 41 (95%) of the pregnant women were unbooked, and about 50% of the women presented at gestational ages of 28-33weeks. Antepartum eclampsia identified as the most common clinical type occurring in 38 (63.3%) of cases and headache was the most common prodromal symptom associated with eclampsia. Majority (86.7%) of the eclamptic women had ceaserean section as their mode of delivery. There were 4 (6.7%) maternal deaths within the study period from eclampsia and 11 (18.3%) of the women had Acute kidney injury among other complications. Twenty-eight women (46.7%) delivered babies that had birth asphyxia and 24(40%) of the babies required admission into the special care baby unit (SCBU). Four (6.7%) of the babies of women with eclampsia during the study period died within the neonatal period. Conclusion: Eclampsia is a leading cause of maternal and perinatal morbidity and mortality especially in developing countries like Nigeria. Therefore, Women should be adequately counseled on preconception care, early booking and regular antenatal care visits, with proper monitoring and control of blood pressure, to enable early detection and effective management to mitigate the associated feto-maternal complications of eclampsia. Prompt diagnosis and management of hypertensive disorders are key in preventing the maternal and perinatal morbidity and mortality that are associated with these disorders.
{"title":"Eclampsia Managed at Nnamdi Azikiwe University Teaching Hospital (NAUTH), NNEWI, South-East Nigeria: A 5-Year Retrospective Cross-Sectional Studya","authors":"Nc Obi, C. Oguejiofor, O. Okafor, G. Eleje, CG Okafor, JC Nkesi, Co Ezeigwe, MC Egbuniwe, BU Odugu, SO Nweze, EA Emeka, C. Ofiaeli, NL Onah, VV Okon, IJ Onyekpa, K. Obioha, B. Okpala, TB Ejikeme, CM Anyaoku, E. Egwuatu, O. Nnabuchi, C. Okeke, SC Egbogu, TN Agbo, OD Ugwu, OC Ekwebene","doi":"10.29011/2577-2236.100165","DOIUrl":"https://doi.org/10.29011/2577-2236.100165","url":null,"abstract":"Background: Obstetric emergencies like eclampsia continue to be a leading cause of morbidity and mortality in pregnant women and fetuses in modern society. Given its detrimental consequences on the pregnant woman, her unborn child, and any later medical difficulties linked to this illness, it has remained to be a cause of concern for obstetricians, especially in low-and middle-income countries. Hence the requirement for periodic review in our environment. Objectives: The objective of this study is to determine the prevalence, pattern of presentation as well as fetal and maternal outcome of cases of eclampsia with a view to suggest interventions to reduce the incidence and associated morbidity and mortality associated with eclampsia. Materials and Methods: This study examines all eclampsia cases treated at Nnamdi Azikiwe University Teaching Hospital (NAUTH), Nnewi, Nigeria between January 1, 2017, and December 31, 2021. The hospital’s medical records division provided access to the case notes of every eclampsia patient. The socio-demographic and clinical data of the subjects were gathered using a systematic proforma, and they were then evaluated and analysed. The teaching hospital’s ethics committee was contacted in order to request and get ethical clearance and permission. The statistical software for social sciences (SPSS) version 25 was used to analyse the data. Results: The eclampsia prevalence rate observed was 1.65%. The ages of the women ranged from 18 to 41 years with mean age and standard deviation given as 26.97 ± 4.61 years. The majority 41 (95%) of the pregnant women were unbooked, and about 50% of the women presented at gestational ages of 28-33weeks. Antepartum eclampsia identified as the most common clinical type occurring in 38 (63.3%) of cases and headache was the most common prodromal symptom associated with eclampsia. Majority (86.7%) of the eclamptic women had ceaserean section as their mode of delivery. There were 4 (6.7%) maternal deaths within the study period from eclampsia and 11 (18.3%) of the women had Acute kidney injury among other complications. Twenty-eight women (46.7%) delivered babies that had birth asphyxia and 24(40%) of the babies required admission into the special care baby unit (SCBU). Four (6.7%) of the babies of women with eclampsia during the study period died within the neonatal period. Conclusion: Eclampsia is a leading cause of maternal and perinatal morbidity and mortality especially in developing countries like Nigeria. Therefore, Women should be adequately counseled on preconception care, early booking and regular antenatal care visits, with proper monitoring and control of blood pressure, to enable early detection and effective management to mitigate the associated feto-maternal complications of eclampsia. Prompt diagnosis and management of hypertensive disorders are key in preventing the maternal and perinatal morbidity and mortality that are associated with these disorders.","PeriodicalId":365505,"journal":{"name":"Obstetrics & Gynecology: Open Access","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129999671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-03DOI: 10.29011/2577-2236.100166
C. Oguejiofor, O. Okafor, G. Eleje, CG Okafor, JC Nkesi, Co Ezeigwe, MC Egbuniwe, BU Odugu, SO Nweze, EA Emeka, C. Ofiaeli, NL Onah, VV Okon, IJ Onyekpa, K. Obioha, B. Okpala, TB Ejikeme, CM Anyaoku, E. Egwuatu, O. Nnabuchi, C. Okeke, SC Egbogu, TN Agbo, OD Ugwu, OC Ekwebene
Background: Infertility is a major cause of marital disharmony in the word most especially in our environment because of the high value system placed on child bearing. Infertility is one of the commonest reason couples presents to a doctor especially the gynecologist. Objectives: This study is to determine the prevalence of infertility, causes, contributions of male and female factors in infertility, and to make recommendations on the management of infertility in NAUTH, Nnewi, Nigeria. Materials and Methods: This is a retrospective study that reviewed all the cases of infertility managed at Nnamdi AzikiweUniversity Teaching Hospital (NAUTH), Nnewi between 1st January 2017 and 31st Dec, 2021. The case notes of all the patients managed for infertility was obtained from the medical records department of the hospital. A structured proforma was used to collect the socio-demographic and clinical data of the subjects to be reviewed and analyzed. Ethical clearance and approval was sought for and obtained from the ethical committee of the teaching hospital. The data was analyzed using Statistical package for social sciences (SPSS) version 25. Results: The infertility prevalence rate of 26.8% was observed. Secondary infertility (55%) was the predominant type of infertility within the study population while the remaining (45%) had primary infertility. Tubal pathology (65%) was the most common cause of infertility identified during this study. Male factor alone contributed 100(11.7%) of the infertility cases, a combination of male and female factors were identified in 325(38%) of couples, female factor alone contributed 388(45.3%) of the cases. However, the cause of infertility was unexplained in 43(5%) of the couples that were studied during the period of this study. Conclusion: Infertility is a common presentation in the gynaecological clinics and the secondary type is predominant in this environment and has been linked to post-infectious causes. Thus, High premium should be placed on primary prevention of the various risk factors that predispose couples to this burden of infertility.
{"title":"A 5-Year Retrospective Cross-Sectional Study of the Pattern of Infertility in Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria","authors":"C. Oguejiofor, O. Okafor, G. Eleje, CG Okafor, JC Nkesi, Co Ezeigwe, MC Egbuniwe, BU Odugu, SO Nweze, EA Emeka, C. Ofiaeli, NL Onah, VV Okon, IJ Onyekpa, K. Obioha, B. Okpala, TB Ejikeme, CM Anyaoku, E. Egwuatu, O. Nnabuchi, C. Okeke, SC Egbogu, TN Agbo, OD Ugwu, OC Ekwebene","doi":"10.29011/2577-2236.100166","DOIUrl":"https://doi.org/10.29011/2577-2236.100166","url":null,"abstract":"Background: Infertility is a major cause of marital disharmony in the word most especially in our environment because of the high value system placed on child bearing. Infertility is one of the commonest reason couples presents to a doctor especially the gynecologist. Objectives: This study is to determine the prevalence of infertility, causes, contributions of male and female factors in infertility, and to make recommendations on the management of infertility in NAUTH, Nnewi, Nigeria. Materials and Methods: This is a retrospective study that reviewed all the cases of infertility managed at Nnamdi AzikiweUniversity Teaching Hospital (NAUTH), Nnewi between 1st January 2017 and 31st Dec, 2021. The case notes of all the patients managed for infertility was obtained from the medical records department of the hospital. A structured proforma was used to collect the socio-demographic and clinical data of the subjects to be reviewed and analyzed. Ethical clearance and approval was sought for and obtained from the ethical committee of the teaching hospital. The data was analyzed using Statistical package for social sciences (SPSS) version 25. Results: The infertility prevalence rate of 26.8% was observed. Secondary infertility (55%) was the predominant type of infertility within the study population while the remaining (45%) had primary infertility. Tubal pathology (65%) was the most common cause of infertility identified during this study. Male factor alone contributed 100(11.7%) of the infertility cases, a combination of male and female factors were identified in 325(38%) of couples, female factor alone contributed 388(45.3%) of the cases. However, the cause of infertility was unexplained in 43(5%) of the couples that were studied during the period of this study. Conclusion: Infertility is a common presentation in the gynaecological clinics and the secondary type is predominant in this environment and has been linked to post-infectious causes. Thus, High premium should be placed on primary prevention of the various risk factors that predispose couples to this burden of infertility.","PeriodicalId":365505,"journal":{"name":"Obstetrics & Gynecology: Open Access","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115772434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-30DOI: 10.29011/2577-2236.100164
Yh Liu
Background: In Taiwan, actual breastfeeding rates fall short of 6 months recommendation duration. 60.2% of infants are breastfed at 1 month, decreasing to 47.3% by 4 months and 37.9% by 6 months. The study aimed to evaluate the effectiveness of telephone-based counselling in encouraging mothers’ breastfeeding duration at least 3 months in Taiwan. Methods: A quasi-experimental design using pre-and post-tests with intervention and control groups was selected for the study. A total 79 mothers were invited to participate randomized into either experimental group (n=40) or control group (n=39). Both groups received usual care during hospitalization but the experimental group received a scheduled telephone interviews after discharge from hospitals. Both groups will have a pre-test before discharge from hospital, a post-test at 1 month, 2 months, and 3 months. Breastfeeding Self-Efficacy Scale (BSES) were used to measure breastfeeding confidence. Results: The repeat measures ANOVA revealed no interaction effect for time by group (F (3, 44) = .71, p=.55). Similarly, there was no significant main effect for time (F (3,44) = .20, p=.90) or for group (F (1,22) = .27, p=.60). The only predictor and positive related to higher scores in BSES was the length of previous breastfeeding (P<.005). Conclusion: Although not a statistically significant difference, there are 23 out of 40 mothers in experimental group still having breastfeeding compared to 1 out of 39 mothers in control group in the third month.
{"title":"Does Telephone Counselling Promote Breast Feeding Duration in Taiwan?","authors":"Yh Liu","doi":"10.29011/2577-2236.100164","DOIUrl":"https://doi.org/10.29011/2577-2236.100164","url":null,"abstract":"Background: In Taiwan, actual breastfeeding rates fall short of 6 months recommendation duration. 60.2% of infants are breastfed at 1 month, decreasing to 47.3% by 4 months and 37.9% by 6 months. The study aimed to evaluate the effectiveness of telephone-based counselling in encouraging mothers’ breastfeeding duration at least 3 months in Taiwan. Methods: A quasi-experimental design using pre-and post-tests with intervention and control groups was selected for the study. A total 79 mothers were invited to participate randomized into either experimental group (n=40) or control group (n=39). Both groups received usual care during hospitalization but the experimental group received a scheduled telephone interviews after discharge from hospitals. Both groups will have a pre-test before discharge from hospital, a post-test at 1 month, 2 months, and 3 months. Breastfeeding Self-Efficacy Scale (BSES) were used to measure breastfeeding confidence. Results: The repeat measures ANOVA revealed no interaction effect for time by group (F (3, 44) = .71, p=.55). Similarly, there was no significant main effect for time (F (3,44) = .20, p=.90) or for group (F (1,22) = .27, p=.60). The only predictor and positive related to higher scores in BSES was the length of previous breastfeeding (P<.005). Conclusion: Although not a statistically significant difference, there are 23 out of 40 mothers in experimental group still having breastfeeding compared to 1 out of 39 mothers in control group in the third month.","PeriodicalId":365505,"journal":{"name":"Obstetrics & Gynecology: Open Access","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134434315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-27DOI: 10.29011/25772236.100163
K. Underkofler, M. Towner, A. Urh, Myla Strawder-man, K. Robison, Richard G. Moore
Background: Isolated tumor cells (ITCs) are deposits measuring ≤0.2 mm, whereas micro metastasis (MM) measures >0.2 to ≤2 mm. The significance of these findings in endometrial cancer remains controversial. We sought to determine whether patient and disease characteristics correlate with ITCs/MM on sentinel lymph node (SLN) biopsy for endometrial cancer staging. Methods: We carried out an IRB-approved retrospective chart review of all women with endometrial cancer who underwent SLN biopsy during staging at two medical centers between 2013 and 2018. Results: A total of 472 patient charts met inclusion criteria. Among women included, 5.7% (n = 27) had ITCs/MM. The median age of women with ITCs/MM was 64 years and median BMI was 33.8. Neither was found to be related to ITCs/M. Lymphovascular space invasion (LVSI) was present in 73% (n = 19). Compared to patients without LVSI, those with LVSI were more likely to have ITCs/MM (OR = 7.61, 95% CI 3.00–19.32). Compared to patients with superficial invasion of the myometrium, those with a greater myometrial invasion were more likely to have ITCs/MM (OR = 6.37, 95% CI 1.90–21.37). Conclusion: ITCs/MM are relatively rare in women undergoing SLN biopsy for endometrial cancer. Additional data are needed to clarify risk factors and associated patient outcomes.
背景:分离的肿瘤细胞(ITCs)是直径≤0.2 mm的沉积物，而微转移(mm)的直径>0.2至≤2mm。这些发现在子宫内膜癌中的意义仍有争议。我们试图确定患者和疾病特征是否与前哨淋巴结(SLN)活检诊断子宫内膜癌分期的ITCs/MM相关。方法:我们对2013年至2018年在两个医疗中心分期期间接受SLN活检的所有子宫内膜癌女性进行了irb批准的回顾性图表回顾。结果:共有472张患者图表符合纳入标准。在纳入的女性中，5.7% (n = 27)患有ITCs/MM。ITCs/MM女性的中位年龄为64岁，中位BMI为33.8。两者均未发现与ITCs/M有关。73% (n = 19)存在淋巴血管间隙浸润(LVSI)。与没有LVSI的患者相比，LVSI患者更容易发生ITCs/MM (OR = 7.61, 95% CI 3.00-19.32)。与肌层浅表侵犯的患者相比，肌层侵犯较大的患者更容易发生ITCs/MM (OR = 6.37, 95% CI 1.90-21.37)。结论:ITCs/MM在接受子宫内膜癌SLN活检的女性中相对罕见。需要更多的数据来澄清风险因素和相关的患者预后。
{"title":"Characterization of Patients with Endometrial Cancer and Low-Volume Nodal Disease","authors":"K. Underkofler, M. Towner, A. Urh, Myla Strawder-man, K. Robison, Richard G. Moore","doi":"10.29011/25772236.100163","DOIUrl":"https://doi.org/10.29011/25772236.100163","url":null,"abstract":"Background: Isolated tumor cells (ITCs) are deposits measuring ≤0.2 mm, whereas micro metastasis (MM) measures >0.2 to ≤2 mm. The significance of these findings in endometrial cancer remains controversial. We sought to determine whether patient and disease characteristics correlate with ITCs/MM on sentinel lymph node (SLN) biopsy for endometrial cancer staging. Methods: We carried out an IRB-approved retrospective chart review of all women with endometrial cancer who underwent SLN biopsy during staging at two medical centers between 2013 and 2018. Results: A total of 472 patient charts met inclusion criteria. Among women included, 5.7% (n = 27) had ITCs/MM. The median age of women with ITCs/MM was 64 years and median BMI was 33.8. Neither was found to be related to ITCs/M. Lymphovascular space invasion (LVSI) was present in 73% (n = 19). Compared to patients without LVSI, those with LVSI were more likely to have ITCs/MM (OR = 7.61, 95% CI 3.00–19.32). Compared to patients with superficial invasion of the myometrium, those with a greater myometrial invasion were more likely to have ITCs/MM (OR = 6.37, 95% CI 1.90–21.37). Conclusion: ITCs/MM are relatively rare in women undergoing SLN biopsy for endometrial cancer. Additional data are needed to clarify risk factors and associated patient outcomes.","PeriodicalId":365505,"journal":{"name":"Obstetrics & Gynecology: Open Access","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130532165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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