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Elimination of Congenital Syphilis in Thailand: What can be done during antenatal period? (doi: 10.14456/tjog.2016.16) 在泰国消除先天性梅毒:在产前可以做些什么?(doi: 10.14456 / tjog.2016.16)
Q4 Medicine Pub Date : 2016-06-30 DOI: 10.14456/TJOG.2016.16
Chenchit Chayachinda
Congenital syphilis (CS) is an infection in infants born to mothers infected by Treponema pallidum. It is transmitted via placenta or direct exposure to vaginal secretion during vaginal birth. World Health Organization aims to eliminate CS by 2015, which is defied as an incidence of 0.5 cases or fewer per 1,000 births. Thailand has already achieved the goal for many years. However, new syphilis cases have been increasingly reported, especially among young people. The National Guideline on the management for the elimination of congenital syphilis in Thailand, 2015 has been developed to tackle the problem and enhance the healthcare system for this preventable condition. The optimal goal is to reduce the incidence of CS to less than 0.05 per 1,000 livebirths by 2020. For early detection and early treatment, the guideline focuses on the early ANC and the same-day-result testing of syphilis for pregnant women with late or no ANC. We, obstetricians, can play essential roles in this mission.
先天性梅毒(CS)是感染梅毒螺旋体的母亲所生婴儿的一种感染。它通过胎盘或阴道分娩时直接接触阴道分泌物传播。世界卫生组织的目标是到2015年消除小儿麻痹症,该疾病的发病率为每1000个新生儿中0.5例或更少。泰国多年来已经实现了这一目标。然而,新的梅毒病例报告越来越多,特别是在年轻人中。泰国制定了《2015年消除先天性梅毒管理国家指南》,以解决这一问题并加强针对这一可预防疾病的卫生保健系统。最理想的目标是到2020年将CS的发病率降低到每1000例活产0.05例以下。在早期发现和早期治疗方面,该指南侧重于晚期或无ANC的孕妇的早期ANC和梅毒当日结果检测。作为产科医生,我们可以在这项任务中发挥重要作用。
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引用次数: 1
Cesarean Section Rate in Oxytocin Infusion between Continuous Until Delivery and Discontinuation at Active Phase of Labor: a Randomized Controlled Study 一项随机对照研究:持续输注催产素至分娩与在产程活跃期停止输注催产素的剖宫产率
Q4 Medicine Pub Date : 2016-06-30 DOI: 10.14456/TJOG.2016.17
Lalida Chookijkul, S. Prommas, Piyawan Pariyawateekul, Nawaporn Orungrote, Buppa Smanchat, K. Suwannarurk
Objective: To compare the cesarean section rate between discontinuing oxytocin infusion for labor induction or augmentation when the active phase of labor is established and continuing oxytocin infusion until delivery. Materials and methods: This was a prospective randomized controlled trial of 340 pregnant women who underwent labor induction or augmentation at Bhumibol Adulyadej Hospital during February 2014 to January 2015. Parturient were randomly and equally allocated into two groups. The continued group received oxytocin infusion throughout all stages of labor. The discontinued group received oxytocin infusion and early discontinued when the active phase of labor had begun. Intention to treat analysis was used in this study. Results: Three hundred and forty pregnant women were enrolled for the study. They were assigned randomly into two groups, 170 patients for each group. Cesarean section rate in continued and discontinued group were 31.8% and 27.7%, respectively ( p = 0.40). The infusion of intravenous fluid in CG group was stopped due to non-reassuring fetal heart rate pattern in 15 women and total oxytocin doses used were significantly higher than that in DG group. In DG group, additional oxytocin was required due to poor uterine contraction. Duration of each stage of labor, maternal complications and adverse neonatal outcomes were not significantly different. There were only two cases of postpartum hemorrhage in discontinued group that was successful managed by medical treatment. Conclusion: There was not sufficient evidence to support whether discontinuation or continuation of oxytocin in active phase of labor influenced cesarean section rate. However, higher doses of oxytocin used was found in continuation group. Future well-randomized design with enough sample size is needed.
目的:比较产程活跃期确定后停止催产素输注引产或助产与继续输注催产素直至分娩的剖宫产率。材料和方法:这是一项前瞻性随机对照试验,纳入了2014年2月至2015年1月在普密蓬阿杜德医院接受引产或隆胸术的340名孕妇。将产妇随机平均分为两组。继续组在分娩的所有阶段均接受催产素输注。停药组接受催产素输注,在产程活跃期开始时提前停药。本研究采用意向治疗分析。结果:340名孕妇参加了这项研究。他们被随机分为两组,每组170名患者。继续组和停止组剖宫产率分别为31.8%和27.7% (p = 0.40)。CG组有15例患者因胎心不稳定而停止静脉输液,使用的催产素总剂量显著高于DG组。DG组因子宫收缩不良,需追加催产素。各产程持续时间、产妇并发症及新生儿不良结局无显著差异。停药组仅有2例产后出血经药物治疗成功。结论:产程活跃期停用或继续使用催产素是否影响剖宫产率尚无充分证据支持。然而,在继续组中使用了更高剂量的催产素。未来需要有足够样本量的良好随机设计。
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引用次数: 3
The correlation between Aflatoxin B1 and Placental Apoptosis in Pregnant women with Intrauterine Growth Restriction 黄曲霉毒素B1与宫内生长受限孕妇胎盘凋亡的关系
Q4 Medicine Pub Date : 2016-06-30 DOI: 10.14456/TJOG.2016.8
A. Abbas, M. El-Baz, O. Shaaban, Khalid M. Mohany, Thorya S. El-Deeb, Amira M. El-Noweihi
Objective :  Egypt has one of the highest incidences of intrauterine fetal growth restriction (IUGR) around the world. In the current study, we tried to explore the effect of Aflatoxin B1 toxicity as a risk factor of IUGR and to determine the role of placental apoptotic indices in the pathogenesis of IUGR and their association with maternal risk factors as residency, working and exposure to smoking. Materials and Methods :  A case-control study was done at Women Health Hospital; Assiut University, Egypt included 60 pregnant women with asymmetrical IUGR besides a control group of 40 normal pregnancies were selected. Maternal urine samples were obtained for measuring Aflatoxin B1 level by layer chromatography. Quantitative determination of human placental Bcl-2 and caspase-3 using a monoclonal antibody-based enzyme-linked immunosorbent assay kits were performed. Results : The results showed that aflatoxin B1 positive cases in the IUGR group had significantly higher placental caspase-3 and lower placental Bcl-2 concentrations than those which were aflatoxin B1 negative (p<0.01). The levels of placental apoptotic indices were higher in working women who lived in urban areas and those exposed to cigarette smoke than non-working women who lived in rural areas and non-smokers. Conclusions : Aflatoxin B1 may affect the fetal growth by increasing the placental apoptosis. These results may highlight the importance of aflatoxin B1 which may contribute to the complex etiology of IUGR. Placental apoptotic indices levels were significantly affected by maternal residency, working and exposure to smoking in pregnancies complicated with IUGR.
目的:埃及是世界上宫内胎儿生长受限(IUGR)发病率最高的国家之一。在本研究中,我们试图探讨黄曲霉毒素B1毒性作为IUGR的危险因素的作用,并确定胎盘凋亡指标在IUGR发病中的作用及其与母亲居住、工作和吸烟等危险因素的关系。材料与方法:在妇女保健医院进行病例对照研究;埃及Assiut大学选取60名IUGR不对称孕妇作为对照组,另外选取40名正常孕妇作为对照组。取产妇尿液样品,用层析法测定黄曲霉毒素B1水平。采用基于单克隆抗体的酶联免疫吸附测定试剂盒定量测定人胎盘Bcl-2和caspase-3。结果:与黄曲霉毒素B1阴性组相比,IUGR组黄曲霉毒素B1阳性组胎盘caspase-3显著升高,胎盘Bcl-2显著降低(p<0.01)。居住在城市地区的职业妇女和吸烟妇女的胎盘凋亡指数水平高于居住在农村地区的非职业妇女和不吸烟妇女。结论:黄曲霉毒素B1可能通过增加胎盘细胞凋亡影响胎儿生长。这些结果可能强调黄曲霉毒素B1的重要性,它可能导致IUGR的复杂病因。妊娠合并IUGR时,产妇居住、工作和吸烟对胎盘凋亡指数水平有显著影响。
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引用次数: 0
Survival rate of endometrial cancer patients at Phramongkutklao Hospital Phramongkutklao医院子宫内膜癌患者的生存率
Q4 Medicine Pub Date : 2016-06-30 DOI: 10.14456/TJOG.2016.9
Sansanee Payanta, Suttida Intharaburan
Objective: To determine the five-year overall survival rate of patients with endometrial cancer after complete treatment at Phramongkutklao hospital. Materials and Method: This was a retrospective descriptive study. A total of 54 patients were enrolled with histologically confirmed diagnosis of endometrial cancer and that had complete treatment from January 1, 2009 to December 31, 2010 at Phramongkutklao hospital. Overall survival was estimated according to the Kaplan-Meier method and univariate analysis employed Log-rank test to compare between groups. Main outcome measure: The five-year overall survival rate of patients with endometrial cancer. Results: The mean age of the 54 patients was 60 ± 10.6 years. All presented symptoms of abnormal uterine bleeding. The majority had early stage disease (66.7%), histopathology cell types were endometrioid carcinoma (90.6%). The majority of adjuvant therapies in advanced stage was chemotherapy plus radiotherapy (27.7%), and early stage was radiotherapy alone (33.4%). The five-year overall survival rate of endometrial cancer was 80.1% that depend on stage were 91.6% in early stage (FIGO stage I-II) and 50% in advanced stage (FIGO stage III-IV). The statistically significant variables affecting overall survival included stage, tumor grade, cervical invasion, lymph nodes metastasis, positive peritoneal cytology and post operative residual tumor more than 2 cm. Conclusion: The five-year overall survival rate of endometrial cancer was 80.1%. The FIGO stage and tumor grade were correlated with overall survival of patients with endometrial cancer.
目的:了解在Phramongkutklao医院接受完全治疗的子宫内膜癌患者的5年总生存率。材料与方法:本研究为回顾性描述性研究。共有54名经组织学证实诊断为子宫内膜癌的患者入组,并于2009年1月1日至2010年12月31日在Phramongkutklao医院接受了完整的治疗。采用Kaplan-Meier法估计总生存率,单因素分析采用Log-rank检验进行组间比较。主要观察指标:子宫内膜癌患者5年总生存率。结果:54例患者平均年龄60±10.6岁。都有异常子宫出血的症状多数为早期病变(66.7%),组织病理细胞类型为子宫内膜样癌(90.6%)。晚期以化疗加放疗为主(27.7%),早期以单纯放疗为主(33.4%)。子宫内膜癌的5年总生存率为80.1%,取决于分期,早期(FIGO I-II期)为91.6%,晚期(FIGO III-IV期)为50%。影响总生存率有统计学意义的变量包括分期、肿瘤分级、宫颈浸润、淋巴结转移、腹膜细胞学阳性和术后肿瘤残留大于2 cm。结论:子宫内膜癌5年总生存率为80.1%。FIGO分期和肿瘤分级与子宫内膜癌患者的总生存期相关。
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引用次数: 0
Postpartum Long-Acting Reversible Contraception Use in Adolescent at Maharat Nakhon Ratchasima Hospital Maharat Nakhon Ratchasima医院青少年产后长效可逆避孕的应用
Q4 Medicine Pub Date : 2016-03-30 DOI: 10.14456/TJOG.2016.2
Lalita Songsathaporn, Siraya Kitiyodom
Objective: To determine the intention and using of long-acting reversible contraception (LARC) in adolescents in the postpartum period. Material and Method: A prospective cohort study was conducted at Maharat Nakhon Ratchasima hospital, from June 2014 to November 2014. Postpartum adolescents under the age of 20 who willing to participate were enrolled in this study. A structured interview questionnaire was used to determine the intention of contraceptive use prior to discharge. Then, phone interviewed at 12 weeks postpartum to determine contraceptive use and reasons. Results: Three hundred and ninety eight of 456 adolescents had a documented postpartum visit at 12 weeks, giving an overall response rate of 87.3%. 336 adolescents (73.7%) intended to use LARC prior to discharge and 209 adolescents (56.9%) had used LARC within 12 weeks postpartum. The most common reason of LARC use was convenience. Injectable contraception was the most common LARC used that included 54.77% of participants. Intended birth interval and pregnancy desire were significant factor of choosing LARC at postpartum ward. Significant factors associated with using LARC at 12 weeks postpartum were intended birth interval and previous contraception. Conclusions: The intention to use LARC was 73.7% and the using rate of LARC at 12 weeks postpartum was 56.9%. Convenience was the most common reason of LARC use at 12 weeks postpartum.
目的:了解青少年产后使用长效可逆避孕(LARC)的意向和使用情况。材料与方法:2014年6月至2014年11月在Maharat Nakhon Ratchasima医院进行了一项前瞻性队列研究。20岁以下的产后青少年自愿参与本研究。使用结构化访谈问卷来确定出院前使用避孕药具的意图。然后,在产后12周进行电话访谈,以确定避孕药的使用情况及其原因。结果:456名青少年中有338人在产后12周进行了有记录的随访,总有效率为87.3%。336名青少年(73.7%)在出院前打算使用LARC, 209名青少年(56.9%)在产后12周内使用了LARC。使用LARC最常见的原因是方便。注射避孕是LARC最常见的使用,包括54.77%的参与者。预期生育间隔和妊娠意愿是产后病房选择LARC的重要因素。与产后12周使用LARC相关的重要因素是预期生育间隔和既往避孕。结论:产后12周使用LARC的意向率为73.7%,LARC的使用率为56.9%。方便是产后12周使用LARC的最常见原因。
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引用次数: 0
Comparison of the Cervical Length during Second Trimester of Pregnancy between Teenage and Adult Primigravidae 少女和成年原鸟妊娠中期宫颈长度的比较
Q4 Medicine Pub Date : 2016-03-30 DOI: 10.14456/TJOG.2016.7
Noochanart Pattanapanyasat, S. Luengratsameerung, Paiboon Charoenchainont
Objective: To compare cervical length at midgestation (18+0 - 23+6 weeks of gestation) between primigravida teenage (<19 years) and adult (≥19 years) pregnant women. Study design: Prospective cohort study Material and methods: A transvaginal ultrasound measurement of cervical length at midgestation was performed in each primigravida teenage or adult pregnant woman who attended our antenatal clinic between June 2014 and February 2015. Cervical length as well as prevalence of shortened cervix (≤ 25 mm) were compared between both groups of women. Results: A total of 44 teenage and 46 adult pregnant women completed the study. The mean cervical length in the teenage group was not significantly different from that in the adult group (34.42 ± 6.71 mm. VS 36.89 ± 7.83 mm; P = 0.112). The prevalence of shortened cervix were also not significantly different between both groups (6.8% VS 6.5%; P = 0.995). Women who had a shortened cervix had a significantly higher prevalence of preterm delivery than those with a normal cervix (83.3% VS 13.1%; P = 0.001). Conclusion: There were no significantly differences in cervical lengths and the prevalence of shortened cervix at midgestation between primigravidae teenage and adult pregnant women.
目的:比较初生少女(<19岁)和成年(≥19岁)孕妇妊娠中期(18+0 ~ 23+6周)宫颈长度。研究设计:前瞻性队列研究材料和方法:对2014年6月至2015年2月在我们产前门诊就诊的每位初潮少女或成年孕妇进行妊娠中期宫颈长度经阴道超声测量。比较两组妇女的宫颈长度和宫颈缩短(≤25mm)的发生率。结果:共有44名青少年和46名成年孕妇完成了研究。青少年组颈椎平均长度(34.42±6.71 mm)与成人组差异无统计学意义。VS 36.89±7.83 mm;P = 0.112)。两组间宫颈缩短的患病率也无显著差异(6.8% VS 6.5%;P = 0.995)。宫颈短的妇女早产的发生率明显高于宫颈正常的妇女(83.3% VS 13.1%;P = 0.001)。结论:初产科少女与成年孕妇妊娠中期宫颈长度及宫颈短缩率无显著差异。
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引用次数: 1
Risk Factors and Health Hazards of Vaginal Infections in Upper Egypt: A Cross Sectional Study 上埃及地区阴道感染的危险因素和健康危害:一项横断面研究
Q4 Medicine Pub Date : 2016-03-30 DOI: 10.14456/TJOG.2016.14
A. Abbas, O. Shaaban, S. Badran, A. Shaltout, A. Nasr, S. A. Abdullah
Objective: The complaint of abnormal vaginal discharge is very common particularly in developing countries with low socioeconomic level as Egypt. The study aims to determine the frequency of vaginal infections among Upper Egypt women with evaluation of the related risk factors and health hazards in addition to study the habit of vaginal douching, its possible relation to vaginal infections. Materials and Methods: A cross sectional observational study was done in Women Health Hospital – Assiut University-Egypt. A trained clinic nurse administered an interview-administered questionnaire to 326 women. Women presented to the outpatient clinic and diagnosed to have any type of vaginal infections were approached for participation. The principle outcome was to study the common predisposing factors, different types of vulvovaginal infection and possible common reproductive hazards. Results: During 6-months’ study period, 3894 patients attended the outpatient Gynecology Clinic, from whom 326 women (8.24%) proved to have vaginal infections. The mean age (±SD) of the study participants was 34.61±9.33 years. The majority of women (89.6%) were housewives, multipara (85.9%), living in rural and semi urban areas (79.5%). Among the study group, candidiasis was the most common type of infection (60.8%). The recurrence rate was high for both bacterial vaginosis “BV” (75.2%) and vulvovaginal candidiasis “VVC” (64.1%). No significant difference between candidiasis and bacterial vaginosis regarding preterm labor, ectopic pregnancy and pelvic inflammatory disease. Conclusions: Vaginal infections are quiet common in our locality with high frequency of recurrence. Vaginal douching is a common practice that may predispose to many reproductive health hazards as preterm labor and pelvic inflammatory disease.
目的:阴道分泌物异常的主诉非常普遍,特别是在埃及等社会经济水平较低的发展中国家。该研究旨在确定上埃及妇女阴道感染的频率,评估相关风险因素和健康危害,并研究阴道冲洗的习惯及其与阴道感染的可能关系。材料和方法:在埃及阿西尤特大学妇女健康医院进行了一项横断面观察研究。一名训练有素的诊所护士对326名妇女进行了问卷调查。到门诊就诊并被诊断患有任何类型阴道感染的妇女被邀请参与研究。主要目的是研究外阴阴道感染的常见易感因素、不同类型的外阴阴道感染以及可能的常见生殖危害。结果:在6个月的研究期间,妇科门诊3894例患者,其中326例(8.24%)女性证实阴道感染。研究参与者的平均年龄(±SD)为34.61±9.33岁。大多数妇女(89.6%)是家庭主妇,多子女(85.9%),生活在农村和半城市地区(79.5%)。在研究组中,念珠菌病是最常见的感染类型(60.8%)。细菌性阴道病(BV)和外阴阴道念珠菌病(VVC)复发率均较高(75.2%)。念珠菌病与细菌性阴道病在早产、异位妊娠和盆腔炎方面无显著差异。结论:阴道感染在我区较为常见,复发率高。阴道灌洗是一种常见的做法,可能导致许多生殖健康危害,如早产和盆腔炎。
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引用次数: 8
Comparison of LATCH Scores at the Second Day Postpartum between Mothers with Cesarean Sections and Those with Normal Deliveries 剖宫产母亲与正常分娩母亲产后第二天LATCH评分的比较
Q4 Medicine Pub Date : 2016-03-30 DOI: 10.14456/TJOG.2016.6
Supree Buranawongtrakoon, Pawin Puapornpong
Objective: The route of delivery effects on breastfeeding. The LATCH score for assessment of breastfeeding practices have been widely used here in Thailand. LATCH scores greater than 8 correlated with exclusive breastfeeding at six weeks postpartum. Materials and Methods: The subjects were 1,316 normal postpartum primiparous women who delivered without complications and their newborns at the HRH Princess Maha Chakri Sririndhorn Medical Center in the Nakhon Nayok province during the period from January 2010 to April 2013. The mothers were categorized in two groups; those who delivered by cesarean section and those with normal deliveries. At the first day postpartum, both groups of mother were encouraged to breastfeed their infant. The mothers were assessed LATCH scores at the second day postpartum prior to discharge. Telephone follow-ups at the sixth week postpartum period were collected and used for exclusive breastfeeding data collection. Demographic data and exclusive breastfeeding rates were analyzed by the t-test, Chi-square test, Odds ratios with 95% confidence intervals and Logistic regression analysis. Results: The data shows that mean of LATCH scores at the second day postpartum were 7.9 ± 1.7 points in cesarean section group and 8.1 ± 1.3 points in normal delivery group. There were statistical differences between the mean in the two groups. the crude odds ratio and adjusted odds ratio of LATCH scores more than 8 between the cesarean section group as compared with the normal delivery group was 0.67 (95% CI 0.42-0.94) and 0.82 (95% CI 0.690.97). By telephone follow up at the sixth week postpartum the number of exclusive breastfeeding mothers were 369 (56.1%) in cesarean section group and 388 (59.0%) in normal delivery group. The most common of breastfeeding cessation at sixth week postpartum was insufficient breast milk. Conclusion: The mothers with cesarean section deliveries had significantly lower LATCH scores than the mothers with normal deliveries. The adjusted odds ratios of LATCH scores greater than 8 between the mothers with cesarean sections and normal deliveries was 0.8.
目的:探讨分娩路径对母乳喂养的影响。用于评估母乳喂养做法的LATCH评分在泰国被广泛使用。LATCH评分大于8分与产后6周纯母乳喂养相关。材料与方法:研究对象为2010年1月至2013年4月在那空Nayok省Maha Chakri sririnhorn公主医疗中心分娩的1316名无并发症的正常产后产妇及其新生儿。母亲们被分为两组;剖宫产和正常分娩者。在产后第一天,两组母亲都被鼓励母乳喂养婴儿。在产后第二天出院前对母亲进行LATCH评分。收集产后第6周的电话随访,并用于纯母乳喂养数据收集。采用t检验、卡方检验、95%置信区间的优势比和Logistic回归分析人口统计学资料和纯母乳喂养率。结果:资料显示,剖宫产组产后第2天的平均LATCH评分为7.9±1.7分,正常分娩组为8.1±1.3分。两组的平均值有统计学差异。剖宫产组与正常分娩组相比,LATCH评分大于8的粗优势比和调整优势比分别为0.67 (95% CI 0.42 ~ 0.94)和0.82 (95% CI 0.690.97)。产后6周电话随访,剖宫产组纯母乳喂养母亲369例(56.1%),正常分娩组388例(59.0%)。产后6周停止母乳喂养最常见的原因是母乳不足。结论:剖宫产产妇的LATCH评分明显低于正常分娩产妇。剖宫产母亲与正常分娩母亲的LATCH评分大于8的调整优势比为0.8。
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引用次数: 2
Comparison of Sublingual and Vaginal Misoprostol for Cervical Ripening before Curettage: A Randomized Controlled Trial 舌下和阴道米索前列醇用于刮除前宫颈成熟的比较:一项随机对照试验
Q4 Medicine Pub Date : 2016-03-30 DOI: 10.14456/TJOG.2016.13
Sukanya Chamnan, Suttida Intharaburan
Objective: To compare the effectiveness and side effects of misoprostol as a cervical ripening agent through two different routes of administration before curettage. Materials and Methods: The study employed a hospital based prospective randomized controlled trial. A total of 70 patients were simple random divided in two groups for 400 micrograms sublingual and vaginal administration. The drug was administered 6 hours before dilatation and curettage or fractional curettage. Efficacy was assessed on cervical dilatation achieved, pain score and vaginal blood loss. The tolerable limit was noted based on side effects. Results: The sublingual group had significantly more cervical dilatation than the vaginal group (median cervical dilatation 7 mm vs. 5 mm, P < 0.001). Significantly less pain scores (VAS) in sublingual group than vaginal group (3.3 vs. 4.8, P < 0.001). Postoperative vaginal blood loss in the sublingual group was significantly greater than the vaginal group (20 ml vs. 10 ml, P < 0.001). Other side effects such as fever, chill, nausea, vomiting and diarrhea did not differ in both groups. Conclusion: Sublingual misoprostol could be more effective for cervical dilatation, but presents greater postoperative vaginal blood loss than vaginal route.
目的:比较米索前列醇作为宫颈催熟剂在刮宫前两种不同给药途径的疗效和不良反应。材料与方法:采用基于医院的前瞻性随机对照试验。将70例患者简单随机分为两组,分别给予400微克舌下和阴道给药。本品于扩张刮除或部分刮除前6小时给药。以宫颈扩张程度、疼痛评分和阴道出血量进行疗效评价。可耐受限度是根据副作用来确定的。结果:舌下组宫颈扩张明显大于阴道组(宫颈扩张中位数为7 mm比5 mm, P < 0.001)。舌下组疼痛评分(VAS)明显低于阴道组(3.3比4.8,P < 0.001)。舌下组术后阴道出血量明显大于阴道组(20 ml vs 10 ml, P < 0.001)。其他副作用,如发烧、发冷、恶心、呕吐和腹泻,在两组中没有差异。结论:舌下米索前列醇用于宫颈扩张更有效,但术后阴道出血量大于阴道途径。
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引用次数: 1
Simple Clinical Maneuver for Reducing Shoulder Pain Following Gynecologic Laparoscopic Surgery at Maharat Nakhonratchasima Hospital: A Randomized Controlled Trial 减轻Maharat Nakhonratchasima医院妇科腹腔镜手术后肩痛的简单临床操作:一项随机对照试验
Q4 Medicine Pub Date : 2016-03-30 DOI: 10.14456/TJOG.2016.15
Chatchai Jantaweetip
Objective: To assess the efficacy of simple clinical maneuver to reduce shoulder pain after gynecologic laparoscopic surgery. Study design: Randomized controlled trial. Method: One hundred and four patients who were scheduled for elective gynecologic laparoscopic surgery were randomly allocated to either the current standard as a control group or to additional efforts to remove residual CO 2 at the end of surgery groups. For 54 patients in control group, CO 2 was removed by passive deflation of the abdominal cavity through the cannula. While in 50 patients in the intervention group, CO 2 was removed by means of Trendelenbrerg position (30 degrees) and a pulmonary recruitment maneuver consisting of 5 manual inflations of lung . Postoperative shoulder pain was recorded on a verbal rating scale (VRS 1-6) at 24, 48 hours after operation. Result: There are no significant differences in age, time of surgery, type of surgery, body mass index between 2 groups  except for the postoperative hospital stay (mean,SD)  which are 2.5 + 0.57 days in the control group compared to 2.1 + 0.47 days in the intervention group (p < 0.001). Postoperative shoulder pain (VRS 2-6) in first 48 hrs was evaluated. The significant pain is found in11 in 50 patients (22%) in the intervention group compared with34 in 54 patients (63%) in the control group (p < 0.001). Conclusion: This simple clinical maneuver can reduce the number of patients complaining of shoulder pain after Gynecologic laparoscopic surgery with statistical significance.
目的:评价临床简单手法减轻妇科腹腔镜术后肩痛的效果。研究设计:随机对照试验。方法:104例计划进行选择性妇科腹腔镜手术的患者被随机分配到当前标准组作为对照组,或在手术结束时额外努力去除残余CO 2。对照组54例患者,通过插管被动放气腹腔排出co2。而在干预组的50例患者中,通过Trendelenbrerg体位(30度)和由5次手动肺充气组成的肺复吸手法去除CO 2。术后肩痛在术后24、48小时用口头评定量表(VRS 1-6)记录。结果:两组患者在年龄、手术时间、手术类型、体重指数等方面差异均无统计学意义(p < 0.001),但对照组患者术后住院时间(平均SD)为2.5 + 0.57天,干预组患者为2.1 + 0.47天(p < 0.001)。评估术后48小时内肩痛(VRS 2-6)。干预组50例患者中有11例(22%)出现明显疼痛,对照组54例患者中有34例(63%)出现明显疼痛(p < 0.001)。结论:这种简单的临床手法可以减少妇科腹腔镜手术后肩痛的主诉人数,具有统计学意义。
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引用次数: 0
期刊
Thai Journal of Obstetrics and Gynaecology
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