Pub Date : 2025-07-02DOI: 10.4274/TurkJOrthod.2025.2024.38
Rachele Podda, Francesca Imondi, Adriana Assunta De Stefano, Martina Horodynski, Roberto Antonio Vernucci, Gabriella Galluccio
The aim of this systematic review was to evaluate the clinical outcomes of skeletal anchorage, compared to conventional anchorage, in the treatment of skeletal Class III malocclusion in growing patients. A systematic review was conducted following PRISMA guidelines. A specific search strategy was developed for PubMed, Web of Science, Embase, and Cochrane searching for randomized controlled trials and non-randomized clinical trials. Eleven interventions were assessed, three employing conventional anchorage (group A) and eight skeletal anchorage (group B). Nine pre-treatment (T0) and post-treatment (T1) mean cephalometric outcomes were statistically polled (SNA, SNB, ANB, Wits, Overjet, Overbite, SNMP, IMPA, U1PP). In total, 196 studies were identified, 17 studies were included in the qualitative and quantitative analysis. In the skeletal anchorage group, a greater increase in both ANB (+2.511°) and Wits (+4.691 mm) were observed and the increase in SNMP resulted well-controlled (+0.758°). The conventional anchorage group showed higher dentoalveolar side effects: increase in U1PP (+5.624°), decrease in IMPA (-0.866°) and increase in overjet (+5.255 mm). Treatments exploiting skeletal anchorage determined a better correction of skeletal Class III, thanks to a combination of greater advancement of the maxilla and more enhanced retrusion of the mandible. In all treatment protocols exploiting dental anchorage, the increase in the inclination of the central incisor resulted significantly greater. Further longitudinal studies are required to evaluate the long-term effects of skeletal anchorage in growing patients.
本系统综述的目的是评估骨支抗与传统支抗在治疗生长患者骨III类错牙合中的临床效果。按照PRISMA的指导方针进行了系统的审查。为PubMed、Web of Science、Embase和Cochrane开发了一种特定的搜索策略,用于搜索随机对照试验和非随机临床试验。评估了11种干预措施,其中3种采用常规锚固(A组),8种采用骨骼锚固(B组)。统计9个治疗前(T0)和治疗后(T1)的平均头测量结果(SNA、SNB、ANB、Wits、Overjet、Overbite、SNMP、IMPA、U1PP)。总共确定了196项研究,其中17项研究被纳入定性和定量分析。在骨支具组中,ANB(+2.511°)和Wits (+4.691 mm)均有较大的增加,SNMP的增加得到了很好的控制(+0.758°)。常规支抗组牙槽副反应明显,U1PP升高(+5.624°),IMPA降低(-0.866°),overjet升高(+5.255 mm)。利用骨骼锚定的治疗确定了更好的骨骼III类矫正,这要归功于上颌骨更大的前移和下颌骨更强的后缩。在所有使用牙支抗的治疗方案中,中切牙的倾斜度增加的结果明显更大。需要进一步的纵向研究来评估骨骼锚定对生长患者的长期影响。
{"title":"Clinical Outcomes of Skeletal Anchorage Versus Conventional Anchorage in the Class III Orthopaedic Treatment in Growing Patients: A Systematic Review and Meta-Analysis.","authors":"Rachele Podda, Francesca Imondi, Adriana Assunta De Stefano, Martina Horodynski, Roberto Antonio Vernucci, Gabriella Galluccio","doi":"10.4274/TurkJOrthod.2025.2024.38","DOIUrl":"10.4274/TurkJOrthod.2025.2024.38","url":null,"abstract":"<p><p>The aim of this systematic review was to evaluate the clinical outcomes of skeletal anchorage, compared to conventional anchorage, in the treatment of skeletal Class III malocclusion in growing patients. A systematic review was conducted following PRISMA guidelines. A specific search strategy was developed for PubMed, Web of Science, Embase, and Cochrane searching for randomized controlled trials and non-randomized clinical trials. Eleven interventions were assessed, three employing conventional anchorage (group A) and eight skeletal anchorage (group B). Nine pre-treatment (T0) and post-treatment (T1) mean cephalometric outcomes were statistically polled (SNA, SNB, ANB, Wits, Overjet, Overbite, SNMP, IMPA, U1PP). In total, 196 studies were identified, 17 studies were included in the qualitative and quantitative analysis. In the skeletal anchorage group, a greater increase in both ANB (+2.511°) and Wits (+4.691 mm) were observed and the increase in SNMP resulted well-controlled (+0.758°). The conventional anchorage group showed higher dentoalveolar side effects: increase in U1PP (+5.624°), decrease in IMPA (-0.866°) and increase in overjet (+5.255 mm). Treatments exploiting skeletal anchorage determined a better correction of skeletal Class III, thanks to a combination of greater advancement of the maxilla and more enhanced retrusion of the mandible. In all treatment protocols exploiting dental anchorage, the increase in the inclination of the central incisor resulted significantly greater. Further longitudinal studies are required to evaluate the long-term effects of skeletal anchorage in growing patients.</p>","PeriodicalId":37013,"journal":{"name":"Turkish Journal of Orthodontics","volume":"38 2","pages":"133-141"},"PeriodicalIF":0.8,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12236123/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-02DOI: 10.4274/TurkJOrthod.2025.2025.28
Hatice Başaran Bal, Celal Irgın
Objective: The aim of this study is to evaluate the effects of maxillary advancement (MxA) and bimaxillary osteotomy (MdS-MxA) on upper pharyngeal airway volume (PAV), apnea-hypopnea index (AHI), hyoid bone (HB) position, and head posture (HP) in young and healthy individuals with skeletal Class III malocclusion.
Methods: This prospective clinical study included three groups: MxA, MdS-MxA, and Class I control group, with 12 subjects each. In the surgical groups, lateral cephalometric radiographs, cone-beam computed tomography images, and AHI measurements were obtained preoperatively and approximately six months postoperatively. Only pre-treatment records were collected for the control group. Depending on data distribution, parametric (Paired Samples t-test and ANOVA) or non-parametric (Wilcoxon Signed-Rank and Kruskal-Wallis) tests were used for intra- and inter-group statistical comparisons, with a significance level set at p<0.05.
Results: The maxillary forward movement for the MxA group was 5.34 mm. It was 5.32 mm in the MdS-MxA group, and the mandibular setback was 4.71 mm. Nearly six months after surgery, significant differences were observed among the groups in the sagittal positions of the jaws, the vertical position of the mandible, the vertical position of the hyoid bone, and PAV sections. No significant differences were found in HP, minimum cross-sectional area or AHI.
Conclusion: PAV increase was observed in both surgical groups. MdS-MxA did not have an effect on obstructive sleep apnea. Postoperative HB displacement was minimal, with a slight inferior shift observed in the MdS-MxA group.
{"title":"Comparative Effects of Maxillary Advancement Alone and in Combination with Mandibular Setback on Airway Anatomy and Function in Class III Malocclusion: A Controlled Prospective Clinical Study.","authors":"Hatice Başaran Bal, Celal Irgın","doi":"10.4274/TurkJOrthod.2025.2025.28","DOIUrl":"10.4274/TurkJOrthod.2025.2025.28","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study is to evaluate the effects of maxillary advancement (MxA) and bimaxillary osteotomy (MdS-MxA) on upper pharyngeal airway volume (PAV), apnea-hypopnea index (AHI), hyoid bone (HB) position, and head posture (HP) in young and healthy individuals with skeletal Class III malocclusion.</p><p><strong>Methods: </strong>This prospective clinical study included three groups: MxA, MdS-MxA, and Class I control group, with 12 subjects each. In the surgical groups, lateral cephalometric radiographs, cone-beam computed tomography images, and AHI measurements were obtained preoperatively and approximately six months postoperatively. Only pre-treatment records were collected for the control group. Depending on data distribution, parametric (Paired Samples t-test and ANOVA) or non-parametric (Wilcoxon Signed-Rank and Kruskal-Wallis) tests were used for intra- and inter-group statistical comparisons, with a significance level set at p<0.05.</p><p><strong>Results: </strong>The maxillary forward movement for the MxA group was 5.34 mm. It was 5.32 mm in the MdS-MxA group, and the mandibular setback was 4.71 mm. Nearly six months after surgery, significant differences were observed among the groups in the sagittal positions of the jaws, the vertical position of the mandible, the vertical position of the hyoid bone, and PAV sections. No significant differences were found in HP, minimum cross-sectional area or AHI.</p><p><strong>Conclusion: </strong>PAV increase was observed in both surgical groups. MdS-MxA did not have an effect on obstructive sleep apnea. Postoperative HB displacement was minimal, with a slight inferior shift observed in the MdS-MxA group.</p>","PeriodicalId":37013,"journal":{"name":"Turkish Journal of Orthodontics","volume":"38 2","pages":"107-115"},"PeriodicalIF":0.8,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12236119/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-27DOI: 10.4274/TurkJOrthod.2024.2024.41
Yasemin Tunca, Yeşim Kaya
Objective: This study aims to evaluate the effect of low-level laser therapy (LLLT) on leveling mandibular anterior crowding and associated pain levels.
Methods: This double-blinded, parallel, randomized clinical trial included 30 participants who were randomly assigned to the laser group or the control group, with Little's irregularity index of 4-8 mm in the mandibular canine-canine region. Nickel-titanium archwires measuring 0.012 inches were tied with elastomeric ligatures and changed every 14 days throughout the leveling process. The leveling duration was recorded in days, from the bonding application to the end of leveling. Irradiation was performed at an 810-nm wavelength using a gallium-aluminum-arsenide diode laser device with a power output of 100 mW and an energy density of 8 J/cm². Laser applications were performed after archwire ligation (day 0), on days 3, 7, and 14 and every 14 days until leveling was completed. The leveling duration was calculated, and pain levels were evaluated using a visual analogue scale (VAS) after archwire ligation (hour 0), at hours 2 and 6 and on days 1, 3, 7, 14, and 21.
Results: The leveling duration showed no significant differences between the laser and control groups (p=0.170). Group comparison results of the VAS scores at hour 6 (p=0.001) and day 1 (p=0.006) exhibited significantly reduced pain levels in the laser group compared with the control group.
Conclusion: Although LLLT is not effective in reducing the leveling duration, it significantly reduces pain levels at hour 6 and on the 1st day.
{"title":"Evaluation of the Effect of Low-level Laser Therapy on Leveling Mandibular Anterior Crowding.","authors":"Yasemin Tunca, Yeşim Kaya","doi":"10.4274/TurkJOrthod.2024.2024.41","DOIUrl":"10.4274/TurkJOrthod.2024.2024.41","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to evaluate the effect of low-level laser therapy (LLLT) on leveling mandibular anterior crowding and associated pain levels.</p><p><strong>Methods: </strong>This double-blinded, parallel, randomized clinical trial included 30 participants who were randomly assigned to the laser group or the control group, with Little's irregularity index of 4-8 mm in the mandibular canine-canine region. Nickel-titanium archwires measuring 0.012 inches were tied with elastomeric ligatures and changed every 14 days throughout the leveling process. The leveling duration was recorded in days, from the bonding application to the end of leveling. Irradiation was performed at an 810-nm wavelength using a gallium-aluminum-arsenide diode laser device with a power output of 100 mW and an energy density of 8 J/cm². Laser applications were performed after archwire ligation (day 0), on days 3, 7, and 14 and every 14 days until leveling was completed. The leveling duration was calculated, and pain levels were evaluated using a visual analogue scale (VAS) after archwire ligation (hour 0), at hours 2 and 6 and on days 1, 3, 7, 14, and 21.</p><p><strong>Results: </strong>The leveling duration showed no significant differences between the laser and control groups (p=0.170). Group comparison results of the VAS scores at hour 6 (p=0.001) and day 1 (p=0.006) exhibited significantly reduced pain levels in the laser group compared with the control group.</p><p><strong>Conclusion: </strong>Although LLLT is not effective in reducing the leveling duration, it significantly reduces pain levels at hour 6 and on the 1<sup>st</sup> day.</p>","PeriodicalId":37013,"journal":{"name":"Turkish Journal of Orthodontics","volume":"38 1","pages":"49-55"},"PeriodicalIF":0.8,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11977434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-27DOI: 10.4274/TurkJOrthod.2025.2024.30
İrem Yılmaz, Merve Gonca
Objective: To compare skeletal ages determined using three different regression methods from measurements made on cervical vertebrae from lateral cephalometric radiographs (LCRs) with the skeletal age determined from hand-wrist radiographs (HWRs).
Methods: LCRs and HWRs of 794 individuals (329 boys, 465 girls) aged 7-18 years were examined. The hand-wrist skeletal age of the participants was determined using the Greulich-Pyle (GP) atlas. Forty-four linear and nine angular morphometric measurements in the C2-C5 vertebrae were made in LCRs. Vertebral skeletal age (VSA) was determined in both sexes using Ridge, the least absolute shrinkage and selection operator (LASSO), and ElasticNet regression methods. The study results were evaluated using R2 (explainability power). Bland-Altman analysis was performed to determine the consistency of chronologic age (CA), GP age, and VSAs.
Results: LASSO regression showed the highest explainability power for VSA, with boys at 0.783 and girls at 0.741. In both sexes, the vertebral depth of concavities had high beta coefficients, and the posterior height of C3 vertebrae (TVup-TVlp) had the highest beta coefficient in boys in LASSO regression. The width of the limits of agreement in both CA and VSA graphs of GP age was wider in boys than in girls. The width of the limits of agreement of CA-VSAs was wider in girls than in boys.
Conclusion: Although high R2 values were obtained, VSA showed no superiority over CA in the assessment of skeletal age, and no significant clinical advantage was observed. For the Turkish population, using GP age may be more accurate for determining skeletal age in orthodontic treatment planning.
目的比较根据头颅侧位X光片(LCR)对颈椎的测量结果用三种不同的回归方法确定的骨骼年龄与根据手-腕X光片(HWR)确定的骨骼年龄:检查了 794 名 7-18 岁儿童(329 名男孩,465 名女孩)的头颅侧位X光片和手-腕位X光片。采用格雷利希-派尔(Greulich-Pyle,GP)地图册确定了参与者的手-腕骨骼年龄。在 LCR 中对 C2-C5 椎体进行了 44 次线性和 9 次角度形态测量。使用 Ridge、最小绝对收缩和选择算子(LASSO)以及 ElasticNet 回归方法确定了男女的椎体骨骼年龄(VSA)。研究结果使用 R2(解释力)进行评估。进行了Bland-Altman分析,以确定年代学年龄(CA)、GP年龄和VSAs的一致性:结果:LASSO 回归结果显示,VSA 的可解释力最高,男孩为 0.783,女孩为 0.741。在两性中,椎体凹陷深度的贝塔系数都很高,而在 LASSO 回归中,C3 椎体后方高度(TVup-TVlp)在男孩中的贝塔系数最高。在 GP 年龄的 CA 和 VSA 曲线图中,男孩的一致性界限宽度比女孩宽。结论:结论:虽然获得了较高的 R2 值,但在评估骨骼年龄方面,VSA 并未显示出优于 CA,也未观察到明显的临床优势。对于土耳其人来说,在正畸治疗计划中使用 GP 年龄来确定骨骼年龄可能更准确。
{"title":"Prediction of Skeletal Age Through Cervical Vertebral Measurements Using Different Machine Learning Regression Methods.","authors":"İrem Yılmaz, Merve Gonca","doi":"10.4274/TurkJOrthod.2025.2024.30","DOIUrl":"10.4274/TurkJOrthod.2025.2024.30","url":null,"abstract":"<p><strong>Objective: </strong>To compare skeletal ages determined using three different regression methods from measurements made on cervical vertebrae from lateral cephalometric radiographs (LCRs) with the skeletal age determined from hand-wrist radiographs (HWRs).</p><p><strong>Methods: </strong>LCRs and HWRs of 794 individuals (329 boys, 465 girls) aged 7-18 years were examined. The hand-wrist skeletal age of the participants was determined using the Greulich-Pyle (GP) atlas. Forty-four linear and nine angular morphometric measurements in the C2-C5 vertebrae were made in LCRs. Vertebral skeletal age (VSA) was determined in both sexes using Ridge, the least absolute shrinkage and selection operator (LASSO), and ElasticNet regression methods. The study results were evaluated using R2 (explainability power). Bland-Altman analysis was performed to determine the consistency of chronologic age (CA), GP age, and VSAs.</p><p><strong>Results: </strong>LASSO regression showed the highest explainability power for VSA, with boys at 0.783 and girls at 0.741. In both sexes, the vertebral depth of concavities had high beta coefficients, and the posterior height of C3 vertebrae (TVup-TVlp) had the highest beta coefficient in boys in LASSO regression. The width of the limits of agreement in both CA and VSA graphs of GP age was wider in boys than in girls. The width of the limits of agreement of CA-VSAs was wider in girls than in boys.</p><p><strong>Conclusion: </strong>Although high R2 values were obtained, VSA showed no superiority over CA in the assessment of skeletal age, and no significant clinical advantage was observed. For the Turkish population, using GP age may be more accurate for determining skeletal age in orthodontic treatment planning.</p>","PeriodicalId":37013,"journal":{"name":"Turkish Journal of Orthodontics","volume":"38 1","pages":"36-48"},"PeriodicalIF":0.8,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11976326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-27DOI: 10.4274/TurkJOrthod.2024.2023.140
Semanur Çetin, Berat Serdar Akdeniz
Objective: This study aimed to evaluate proximal caries formation and Decay, Missing, Filled Teeth (DMFT) scores during clear aligner (CA) therapy compared with fixed orthodontic treatment.
Methods: A total of 50 patients with a mean age of 19.9 years were divided into two equal groups (n=25) according to treatment method. Both CA and fixed appliance (FA) patients had low-to-medium levels of crowding. Caries formation and DMFT scores were assessed via radiographic and clinical examination before treatment (T0) and at the end of a six-month observation period (T1). The numbers of caries lesions and fillings was analyzed using a Two-Way Analysis of Variance with a significance level of 0.05.
Results: Significant statistical differences were found for both groups (p<0.001). The amount of proximal caries significantly increased in both groups, whereas the increase in non-proximal caries was only statistically significant in the FA group. DMFT scores also increased significantly in both groups, with the FA group showing a higher increase at the end of the observation period.
Conclusion: Although CAs had an advantage in decreasing the overall risk of caries, no distinct advantage was found in reducing the risk of proximal caries lesions. The DMFT index was significantly higher in fixed orthodontic treatment patients than in CA treatment patients.
目的:本研究旨在评估透明矫正器(CA)治疗与固定正畸治疗期间近端龋形成和龋缺补(DMFT)评分。方法:50例患者,平均年龄19.9岁,按治疗方法分为两组(n=25)。CA和固定矫治器(FA)患者均有低至中等程度的拥挤。在治疗前(T0)和6个月观察期结束时(T1),通过x线摄影和临床检查评估龋形成和DMFT评分。采用双向方差分析(Two-Way Analysis of Variance)分析龋损数和填充物数,显著性水平为0.05。结果:两组比较差异有统计学意义(p)。结论:虽然ca在降低整体龋病风险上有优势,但在降低近端龋病风险上无明显优势。固定正畸治疗组DMFT指数明显高于CA治疗组。
{"title":"Comparative Study of Proximal Caries Formation and Decay, Missing, Filled Teeth Scores in Clear Aligners and Fixed Orthodontic Treatments.","authors":"Semanur Çetin, Berat Serdar Akdeniz","doi":"10.4274/TurkJOrthod.2024.2023.140","DOIUrl":"10.4274/TurkJOrthod.2024.2023.140","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate proximal caries formation and Decay, Missing, Filled Teeth (DMFT) scores during clear aligner (CA) therapy compared with fixed orthodontic treatment.</p><p><strong>Methods: </strong>A total of 50 patients with a mean age of 19.9 years were divided into two equal groups (n=25) according to treatment method. Both CA and fixed appliance (FA) patients had low-to-medium levels of crowding. Caries formation and DMFT scores were assessed via radiographic and clinical examination before treatment (T0) and at the end of a six-month observation period (T1). The numbers of caries lesions and fillings was analyzed using a Two-Way Analysis of Variance with a significance level of 0.05.</p><p><strong>Results: </strong>Significant statistical differences were found for both groups (p<0.001). The amount of proximal caries significantly increased in both groups, whereas the increase in non-proximal caries was only statistically significant in the FA group. DMFT scores also increased significantly in both groups, with the FA group showing a higher increase at the end of the observation period.</p><p><strong>Conclusion: </strong>Although CAs had an advantage in decreasing the overall risk of caries, no distinct advantage was found in reducing the risk of proximal caries lesions. The DMFT index was significantly higher in fixed orthodontic treatment patients than in CA treatment patients.</p>","PeriodicalId":37013,"journal":{"name":"Turkish Journal of Orthodontics","volume":"38 1","pages":"30-35"},"PeriodicalIF":0.8,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11976324/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143732132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tooth eruption is a highly complex mechanism that is controlled by many factors. Various mechanical, systemic, or genetic factors can cause eruption disorders. Primary failure of eruption (PFE) is known as an eruption disorder occurring due to non-syndromic genetic factors. It is frequently seen in the first and second molars and causes posterior open bite. It can be observed unilaterally or bilaterally. Studies show that mutations in many different genes that control the tooth eruption mechanism, mainly the PTH1R and KMT2C genes, constitute the genetic basis of PFE. Primary eruption disorders are very difficult to treat. It is known that the application of active orthodontic forces causes local ankylosis in the tooth and the failure of the tooth to return to its normal position. For this reason, determining the correct diagnosis and treatment method is very important. Although there are different treatment methods, the results of research about the success of these treatment methods are quite limited. This review aims to explain the etiology, diagnosis, and treatment of PFE in light of current genetic studies.
{"title":"Primary Failure of Eruption: A Rare but Desperate Condition for Orthodontic Treatment.","authors":"Yaren Söz, İpek Savkan, Sibel Biren, Zeynep Ahü Acar","doi":"10.4274/TurkJOrthod.2024.2024.51","DOIUrl":"10.4274/TurkJOrthod.2024.2024.51","url":null,"abstract":"<p><p>Tooth eruption is a highly complex mechanism that is controlled by many factors. Various mechanical, systemic, or genetic factors can cause eruption disorders. Primary failure of eruption (PFE) is known as an eruption disorder occurring due to non-syndromic genetic factors. It is frequently seen in the first and second molars and causes posterior open bite. It can be observed unilaterally or bilaterally. Studies show that mutations in many different genes that control the tooth eruption mechanism, mainly the <i>PTH1R</i> and <i>KMT2C</i> genes, constitute the genetic basis of PFE. Primary eruption disorders are very difficult to treat. It is known that the application of active orthodontic forces causes local ankylosis in the tooth and the failure of the tooth to return to its normal position. For this reason, determining the correct diagnosis and treatment method is very important. Although there are different treatment methods, the results of research about the success of these treatment methods are quite limited. This review aims to explain the etiology, diagnosis, and treatment of PFE in light of current genetic studies.</p>","PeriodicalId":37013,"journal":{"name":"Turkish Journal of Orthodontics","volume":"38 1","pages":"56-63"},"PeriodicalIF":0.8,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11976322/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-27DOI: 10.4274/TurkJOrthod.2025.2024.142
Teena Dodeja, Ahmed A Alsulaiman, Leslie A Will, Marianne Saade, Melih Motro
Objective: To assess the effects of rapid maxillary expansion (RME) and orthodontic treatment with fixed appliances on the developing roots of anchor teeth compared with completely formed roots.
Methods: Pre- and post-treatment cone-beam computed tomography (CBCT) scans of 19 patients (mean pre-treatment age 10.9±1.3, mean post-treatment age 13.66±1.29) with incompletely formed roots who had undergone RME and orthodontic treatment with fixed appliances were selected. In addition, 15 CBCT scans of age- and sex-matched untreated controls (mean age 13.69±1.08) with completely formed roots of the same teeth were obtained. Pre- and post-treatment CBCT records of the experimental group were segmented and reconstructed to obtain linear and volumetric measurements of the roots for comparison with the control group. Changes in the root dimensions were analyzed using the paired t-test; Independent Student's t-test was used for comparisons between the groups.
Results: All premolars in the experimental group showed a statistically significant increase in root length and volume post-treatment (p<0.05), with the greatest increase seen in the second premolar. The distobuccal and palatal root lengths of the molars decreased significantly after treatment in the experimental group. The comparison of post-treatment root dimensions between the experimental and untreated control groups showed no significant difference.
Conclusion: The teeth with developing roots attain normal root length after RME and orthodontic treatment with fixed appliances, with no significant differences in root length and volume compared with teeth with completely formed roots.
{"title":"Orthodontic Forces Interrupt Root Formation in Immature Teeth: Myth or Fact? A Pilot Study.","authors":"Teena Dodeja, Ahmed A Alsulaiman, Leslie A Will, Marianne Saade, Melih Motro","doi":"10.4274/TurkJOrthod.2025.2024.142","DOIUrl":"10.4274/TurkJOrthod.2025.2024.142","url":null,"abstract":"<p><strong>Objective: </strong>To assess the effects of rapid maxillary expansion (RME) and orthodontic treatment with fixed appliances on the developing roots of anchor teeth compared with completely formed roots.</p><p><strong>Methods: </strong>Pre- and post-treatment cone-beam computed tomography (CBCT) scans of 19 patients (mean pre-treatment age 10.9±1.3, mean post-treatment age 13.66±1.29) with incompletely formed roots who had undergone RME and orthodontic treatment with fixed appliances were selected. In addition, 15 CBCT scans of age- and sex-matched untreated controls (mean age 13.69±1.08) with completely formed roots of the same teeth were obtained. Pre- and post-treatment CBCT records of the experimental group were segmented and reconstructed to obtain linear and volumetric measurements of the roots for comparison with the control group. Changes in the root dimensions were analyzed using the paired t-test; Independent Student's t-test was used for comparisons between the groups.</p><p><strong>Results: </strong>All premolars in the experimental group showed a statistically significant increase in root length and volume post-treatment (p<0.05), with the greatest increase seen in the second premolar. The distobuccal and palatal root lengths of the molars decreased significantly after treatment in the experimental group. The comparison of post-treatment root dimensions between the experimental and untreated control groups showed no significant difference.</p><p><strong>Conclusion: </strong>The teeth with developing roots attain normal root length after RME and orthodontic treatment with fixed appliances, with no significant differences in root length and volume compared with teeth with completely formed roots.</p>","PeriodicalId":37013,"journal":{"name":"Turkish Journal of Orthodontics","volume":"38 1","pages":"12-19"},"PeriodicalIF":0.8,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11976320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-27DOI: 10.4274/TurkJOrthod.2025.2024.102
Aline Gonçalves, Gabriela Barros, Margarida Coelho, Francisca Monteiro, Filipe S Silva, Teresa Pinho
Several procedures have been proposed as adjuvant treatments in orthodontics to accelerate orthodontic tooth movement (OTM). This review aimed to evaluate and compare the effectiveness of surgical and non-surgical techniques in accelerating tooth movement, ascertain the influence of different orthodontic appliances on the rate of tooth movement and analyze their clinical applicability as supportive approaches in orthodontic treatment. A bibliographic search was carried out in April 2024 across Pubmed, Scopus, Web of Science, and the Cochrane Library using combinations of keywords and Medical Subject Heading terms relevant to the topic. The search had no time restriction and was limited to studies published in English. A total of 76 articles were included in this systematic review. Corticotomy exhibited the highest acceleration potential among surgical techniques but is highly invasive and associated with considerable pain and discomfort. Among non-surgical techniques, vibration and photobiomodulation (PBM) showed the most promising results due to their non-invasiveness and effectiveness in accelerating tooth movement. This review provides a comprehensive overview of techniques for accelerating OTM. The literature remains limited in involving surgical and non-surgical procedures using orthodontic aligners, highlighting the need for further research. Considering all the pros and cons, PBM appears to be the most promising technique; however, its effectiveness is yet suboptimal. Future efforts should be dedicated to optimizing PBM protocols to stimulate specific remodeling phenomena, ensuring its establishment as a safe, effective, painless, and non-invasive acceleration technique.
{"title":"Effectiveness of Surgical and Non-Surgical Techniques for Accelerating Orthodontic Tooth Movement in Fixed Appliances and Aligners: A Systematic Review.","authors":"Aline Gonçalves, Gabriela Barros, Margarida Coelho, Francisca Monteiro, Filipe S Silva, Teresa Pinho","doi":"10.4274/TurkJOrthod.2025.2024.102","DOIUrl":"10.4274/TurkJOrthod.2025.2024.102","url":null,"abstract":"<p><p>Several procedures have been proposed as adjuvant treatments in orthodontics to accelerate orthodontic tooth movement (OTM). This review aimed to evaluate and compare the effectiveness of surgical and non-surgical techniques in accelerating tooth movement, ascertain the influence of different orthodontic appliances on the rate of tooth movement and analyze their clinical applicability as supportive approaches in orthodontic treatment. A bibliographic search was carried out in April 2024 across Pubmed, Scopus, Web of Science, and the Cochrane Library using combinations of keywords and Medical Subject Heading terms relevant to the topic. The search had no time restriction and was limited to studies published in English. A total of 76 articles were included in this systematic review. Corticotomy exhibited the highest acceleration potential among surgical techniques but is highly invasive and associated with considerable pain and discomfort. Among non-surgical techniques, vibration and photobiomodulation (PBM) showed the most promising results due to their non-invasiveness and effectiveness in accelerating tooth movement. This review provides a comprehensive overview of techniques for accelerating OTM. The literature remains limited in involving surgical and non-surgical procedures using orthodontic aligners, highlighting the need for further research. Considering all the pros and cons, PBM appears to be the most promising technique; however, its effectiveness is yet suboptimal. Future efforts should be dedicated to optimizing PBM protocols to stimulate specific remodeling phenomena, ensuring its establishment as a safe, effective, painless, and non-invasive acceleration technique.</p>","PeriodicalId":37013,"journal":{"name":"Turkish Journal of Orthodontics","volume":"38 1","pages":"64-79"},"PeriodicalIF":0.8,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11976350/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-27DOI: 10.4274/TurkJOrthod.2024.2024.106
Merve Kurnaz, Bülent Çelik, Emine Kaygısız
Objective: To compare the pharyngeal airway size and area between Class III patients exhibiting optimal vertical growth direction and Class I patients at the MP3cap stage, considering gender differences.
Methods: This retrospective study analyzed pre-treatment cephalograms of a total of 180 patients with Class I (45 girls, 45 boys) and Class III (maxilla or maxillo-mandibular origin) (45 girls, 45 boys) malocclusions. Linear and angular measurements were conducted on lateral cephalograms utilizing the GNU Image Manipulation Program (GIMP 2.10.18, NY, USA; https://www.gimp.org/). The pharyngeal airway areas were computed utilizing AUTOCAD (Autodesk 2018, San Rafael, CA, USA). The Independent Samples t-test and Mann-Whitney U test were employed for comparative analysis of variables across groups. The forward selection method was employed in conjunction with regression analysis.
Results: No significant differences were observed in the nasopharyngeal area (NA; mm2) across the malocclusion groups and genders. In Class III girls, the oropharyngeal area (OA; mm2), retroglossal (RG; mm2) area, and superior pharyngeal space (SPS; mm) were significantly larger than those of Class III boys, and Class I girls (p<0.05). The inferior pharyngeal space (IPS; mm) was significantly larger in Class III girls compared to Class III boys (p<0.05). Girls with Class I/III malocclusions demonstrated a more pronounced head posture than boys (p<0.05).
Conclusion: The findings indicate the necessity of accounting for gender-specific variations in Class I and III patients, as well as evaluating pharyngeal airway characteristics in orthodontic diagnosis and treatment planning. In Class III girls, the OA and RG areas, as well as the superior and inferior pharyngeal spaces, were larger compared to Class III boys.
{"title":"Gender-based Comparison of Pharyngeal Airway Between Class I and Class III Patients During MP3cap Growth Period.","authors":"Merve Kurnaz, Bülent Çelik, Emine Kaygısız","doi":"10.4274/TurkJOrthod.2024.2024.106","DOIUrl":"10.4274/TurkJOrthod.2024.2024.106","url":null,"abstract":"<p><strong>Objective: </strong>To compare the pharyngeal airway size and area between Class III patients exhibiting optimal vertical growth direction and Class I patients at the MP3cap stage, considering gender differences.</p><p><strong>Methods: </strong>This retrospective study analyzed pre-treatment cephalograms of a total of 180 patients with Class I (45 girls, 45 boys) and Class III (maxilla or maxillo-mandibular origin) (45 girls, 45 boys) malocclusions. Linear and angular measurements were conducted on lateral cephalograms utilizing the GNU Image Manipulation Program (GIMP 2.10.18, NY, USA; https://www.gimp.org/). The pharyngeal airway areas were computed utilizing AUTOCAD (Autodesk 2018, San Rafael, CA, USA). The Independent Samples t-test and Mann-Whitney U test were employed for comparative analysis of variables across groups. The forward selection method was employed in conjunction with regression analysis.</p><p><strong>Results: </strong>No significant differences were observed in the nasopharyngeal area (NA; mm<sup>2</sup>) across the malocclusion groups and genders. In Class III girls, the oropharyngeal area (OA; mm<sup>2</sup>), retroglossal (RG; mm<sup>2</sup>) area, and superior pharyngeal space (SPS; mm) were significantly larger than those of Class III boys, and Class I girls (p<0.05). The inferior pharyngeal space (IPS; mm) was significantly larger in Class III girls compared to Class III boys (p<0.05). Girls with Class I/III malocclusions demonstrated a more pronounced head posture than boys (p<0.05).</p><p><strong>Conclusion: </strong>The findings indicate the necessity of accounting for gender-specific variations in Class I and III patients, as well as evaluating pharyngeal airway characteristics in orthodontic diagnosis and treatment planning. In Class III girls, the OA and RG areas, as well as the superior and inferior pharyngeal spaces, were larger compared to Class III boys.</p>","PeriodicalId":37013,"journal":{"name":"Turkish Journal of Orthodontics","volume":"38 1","pages":"20-29"},"PeriodicalIF":0.8,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11976325/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-03-27DOI: 10.4274/TurkJOrthod.2025.2024.156
Gamze Yıldırım, Elvan Önem Özbilen
Objective: This study aimed to investigate the positional changes of maxillary first molars in patients treated with the hybrid hyrax-mentoplate and Cl III elastics combination using cone-beam computed tomography (CBCT).
Methods: Ten patients (7 females-3 males, mean age: 11.66±0.83 years) treated with hybrid hyrax-mentoplate at Marmara University Department of Orthodontics were included. Angular and linear measurements were taken from pre-treatment and post-treatment CBCT images, and changes in maxillary first molar teeth were examined using 3D SLICER version 5.0.2 (www.slicer.org). Statistical significance was set at p≤0.05.
Results: Significant increases were observed in all distance measurements except C16p-C26p in the coronal plane, and significant decreases were observed in angular measurements only at 16mb and 26mb (p≤0.05). All measurements in the sagittal plane significantly increased compared to the vertical and horizontal reference lines (p≤0.001). Angular measurements relative to the palatal reference line significantly increased only in P-16p, P-26mb, and P-26p (p≤0.05). In skeletal measurements, significant changes were observed only in V-A, V-ANS, H-PNS, and V-PNS measurements (p≤0.05). The expansion at the apical level was significantly higher than that at the coronal level (p≤0.05). Compared to the V line, more mesial movement was observed at the coronal level than at the apical level (p≤0.001).
Conclusion: The use of Class III elastics causes greater expansion at the apical level than the coronal. Molar teeth exhibit a mesial movement, but there could be multiple contributing factors. In molars connected to Class III elastics, extrusion occurs. When vertical control is important, appropriate safety measures are advised.
{"title":"Assessment of Maxillary Molar Tooth Changes Caused by Class III Elastics in Hybrid Hyrax-Mentoplate Treatments: A Pilot Study.","authors":"Gamze Yıldırım, Elvan Önem Özbilen","doi":"10.4274/TurkJOrthod.2025.2024.156","DOIUrl":"10.4274/TurkJOrthod.2025.2024.156","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to investigate the positional changes of maxillary first molars in patients treated with the hybrid hyrax-mentoplate and Cl III elastics combination using cone-beam computed tomography (CBCT).</p><p><strong>Methods: </strong>Ten patients (7 females-3 males, mean age: 11.66±0.83 years) treated with hybrid hyrax-mentoplate at Marmara University Department of Orthodontics were included. Angular and linear measurements were taken from pre-treatment and post-treatment CBCT images, and changes in maxillary first molar teeth were examined using 3D SLICER version 5.0.2 (www.slicer.org). Statistical significance was set at p≤0.05.</p><p><strong>Results: </strong>Significant increases were observed in all distance measurements except C16p-C26p in the coronal plane, and significant decreases were observed in angular measurements only at 16mb and 26mb (p≤0.05). All measurements in the sagittal plane significantly increased compared to the vertical and horizontal reference lines (p≤0.001). Angular measurements relative to the palatal reference line significantly increased only in P-16p, P-26mb, and P-26p (p≤0.05). In skeletal measurements, significant changes were observed only in V-A, V-ANS, H-PNS, and V-PNS measurements (p≤0.05). The expansion at the apical level was significantly higher than that at the coronal level (p≤0.05). Compared to the V line, more mesial movement was observed at the coronal level than at the apical level (p≤0.001).</p><p><strong>Conclusion: </strong>The use of Class III elastics causes greater expansion at the apical level than the coronal. Molar teeth exhibit a mesial movement, but there could be multiple contributing factors. In molars connected to Class III elastics, extrusion occurs. When vertical control is important, appropriate safety measures are advised.</p>","PeriodicalId":37013,"journal":{"name":"Turkish Journal of Orthodontics","volume":"38 1","pages":"1-11"},"PeriodicalIF":0.8,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11976321/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143732097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}