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The Dream Experience 梦的经历
Pub Date : 2009-02-15 DOI: 10.4088/PCC.08BK00674
B. Vaidya
The Dream Experience: A Systematic Exploration is a comprehensive text about dreaming. It initially guides the reader through a number of basic concepts about dreaming, including the evidence for dreams actually existing, how dreams are recalled, how dreams are measured and collected in the laboratory, and the range of different types of dreams people experience. It then examines more complex ideas about dream function and meaning. On a personal level, I feel that the subject of dreams is one that was neglected in my own undergraduate medical training, and, although we were taught some basic sleep physiology, the area of dreams had always seemed somewhat mysterious and unscientific. This book has certainly done a good job of filling gaps in my knowledge and has helped me to appreciate the extent of scientific evidence already available in the area. It has provided me with a good foundation to be able to consider and discuss dreams more confidently.
《梦的体验:系统的探索》是一本关于梦的综合性文本。它首先引导读者了解一些关于梦的基本概念,包括梦实际存在的证据,梦是如何被回忆起来的,梦是如何在实验室里被测量和收集的,以及人们经历的不同类型的梦的范围。然后研究关于梦的功能和意义的更复杂的观点。就我个人而言,我觉得梦的主题在我自己的本科医学训练中被忽视了,尽管我们学过一些基本的睡眠生理学,但梦的领域似乎总是有些神秘和不科学。这本书确实很好地填补了我的知识空白,并帮助我了解了该领域已有的科学证据的程度。它为我提供了良好的基础,使我能够更自信地思考和讨论梦想。
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引用次数: 4
Treating the Aching Heart 治疗疼痛的心
Pub Date : 2008-12-15 DOI: 10.4088/PCC.V10N0613A
J. McKrell
I suspect I am like many family physicians, often left to wonder why many of my depressed patients and my patients with heart disease do not seem to respond well to standard treatments. I cannot explain why these patients do not get better or even how they got so sick in the first place. Dr. Wulsin's book illuminates some of the answers to these questions. Treating the Aching Heart is a fascinating and extremely helpful book for both patients and clinicians. The author tackles 2 enormous subjects, depression and coronary artery disease, and explores the pathologic links between the 2 as well as the influences they have on each other. Dr. Wulsin presents his material logically, chapter building upon chapter. He makes a potent argument that Americans pay a high price for ignoring the connection between these 2 common diseases that cause a tremendous burden of suffering for many in the United States. He clearly explains how depression negatively affects the major risk factors for heart disease. He takes us through the current understanding of the neurobiology of depression and then elucidates its links with chronic inflammation and sympathetic nervous system overactivity in the pathophysiology of heart disease. Dr. Wulsin pulls all of this together in several elegant charts and diagrams that he intends to be used as practical tools for the assessment and treatment of depression and heart disease. He closes the book with a challenge to integrate the care of depression and heart disease in our fragmented health care system and so begin to ease the suffering of our patients. This book has multiple features that will be helpful to both patients and the physicians who care for them. The Clinical Tips are practical suggestions that will help patients take a more active role in their treatment. I think the tips may be especially helpful in giving patients practical advice about depression. The appendices contain a number of figures, charts, and Web site links that provide practical tools for both patients and physicians. In particular, I found the Patient Health Questionnaire Depression checklist to be a tool I can easily put to use in my practice. There are several features I particularly enjoyed about the book. Dr. Wulsin's use of clinical vignettes reminded me of my own patients and grounded the book in day to day clinical practice. The figures at the end of chapters 7 and 8 are not just an excellent visual summary of his main thoughts but are also novel clinical tools I am anxious to apply directly to the care of my patients. I expect the visual summary of a patient's risk profile for coronary artery disease will make it easier to provide more comprehensive care. Finally, I appreciated his challenge to join the process of overhauling our health care system and work to integrate the care of these 2 common and debilitating diseases. I think most of us have been frustrated many times by the separation of mental health care and care for physical prob
我怀疑我和许多家庭医生一样,经常疑惑为什么我的许多抑郁症患者和心脏病患者对标准治疗似乎反应不佳。我无法解释为什么这些病人没有好转,甚至他们最初是怎么病得这么重的。伍尔辛博士的书阐明了这些问题的一些答案。治疗疼痛的心是一个迷人的和非常有帮助的书,病人和临床医生。作者处理了两个巨大的主题,抑郁症和冠状动脉疾病,并探讨了两者之间的病理联系以及它们之间的相互影响。伍尔辛博士逻辑地陈述他的材料,一章接一章。他提出了一个强有力的论点,美国人为忽视这两种常见疾病之间的联系付出了高昂的代价,这两种疾病给美国许多人带来了巨大的痛苦负担。他清楚地解释了抑郁症是如何对心脏病的主要风险因素产生负面影响的。他向我们介绍了目前对抑郁症的神经生物学的理解,然后在心脏病的病理生理学中阐明了抑郁症与慢性炎症和交感神经系统过度活跃的联系。伍尔辛博士将所有这些结合在几个优雅的图表中,他打算用这些图表作为评估和治疗抑郁症和心脏病的实用工具。在书的最后,他提出了一个挑战,将抑郁症和心脏病的治疗整合到我们支离破碎的医疗体系中,从而开始减轻病人的痛苦。这本书有多种特点,将有助于病人和医生谁照顾他们。临床提示是实用的建议,可以帮助患者在治疗中发挥更积极的作用。我认为这些建议在给患者提供有关抑郁症的实用建议方面可能特别有用。附录中包含许多图形、图表和网站链接,为患者和医生提供实用工具。特别是,我发现病人健康问卷抑郁症检查表是一个工具,我可以很容易地在我的实践中使用。这本书有几个特点我特别喜欢。伍尔辛博士使用的临床小插图让我想起了我自己的病人,并将这本书建立在日常临床实践的基础上。第七章和第八章末尾的数字不仅是对他主要思想的一个极好的视觉总结,而且也是我急于直接应用于我的病人护理的新颖的临床工具。我希望病人冠状动脉疾病风险概况的可视化总结将使提供更全面的护理变得更容易。最后,我感谢他的挑战,加入改革我们的卫生保健系统的进程,并努力整合这两种常见和使人衰弱的疾病的护理。我想,我们大多数人都曾多次因将心理健康护理和身体问题护理分离成不同的领域而感到沮丧,这些领域很少相互沟通。如果我们感到沮丧,我们的病人会有什么感觉?虽然Wulsin博士指出,关于这两种疾病之间的联系还有很多有待了解的地方,但我对他写的《治疗疼痛的心》感到非常鼓舞。这是一本有用的、有思想的书,值得医学界广泛阅读。我猜想,这将引导人们做出更多努力,将大脑的神经生物学与其他常见疾病过程的病理生理学联系起来。Jonathan D. McKrell,医学博士,宾夕法尼亚州伊利市圣文森特家庭医学
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引用次数: 0
Prevention and Treatment of Suicidal Behaviour 自杀行为的预防和治疗
Pub Date : 2008-12-15 DOI: 10.4088/PCC.v10n0613c
R. Bota
Making any choice creates in us a sense of being vulnerable. With each decision, we lose all the other choices that we did not make. What about the decision to die? Regardless of the cause of suicidal gestures or attempts, the individuals involved usually feel an intense sense of anxiety. One of the reasons is that deciding to die involves no further choices after that. It cannot be undone and people that have reached operational stages of thinking know that. In children, however, suicidality is more dangerous, as they have no or a limited sense of the irreversibility of dying. The majority of the successful acts of suicide are carefully planned in advance. It has been described as a process in which the persons develop suicidal thoughts without a plan but rather a passive desire to “not wake up.” Most often, this ideation disappears for a time or leads to one or several plans regarding the means to be used. This stage can lead to acquiring the means to accomplish this task. It can last for months (e.g., storing months’ worth of prescribed medication). In the time leading up to the act, many individuals go through a testing phase, mainly designed to decrease their anxiety (playing with the gun initially, cocking the gun without ammunition, buying the bullets, and loading the weapon, etc.). This interval often provides a prolonged window of time during which the individual can be identified as at risk by friends or physicians. This progression also might lead to reduction in anxiety about the final act. For example, some Golden Gate Bridge survivors did not report any anxiety symptoms as they fell, but others “changed their mind” about the act of dying.1 In light of the above conceptualization, we can hypothesize that the anxiety of “final choice” occasionally helps overturn the desire to die in some patients, at least for the time necessary to seek help. During this time, those caring for an individual at risk need to assure that the person is observed carefully to promote safety, assess protective and contributory factors, and develop a plan to anticipate and manage future attempts. Unfortunately, even with our best efforts, the rate of completed suicide is high in those who have had a previous attempt. Those in whom thoughts of suicide recur are not “exploring new ground” anymore. They have been there before. We have limited information since patients are often secretive about these thoughts and hide them even from close family and friends. The risk of suicide is highest after hospital discharge in psychiatric patients, particularly if there is a change in provider at the time of discharge. Proposed explanations include that patients return to the same environment that caused their suicidal symptoms, perceive loss of the supports available during hospitalization, perceive a sense of shame about being hospitalized, and perceive “inadequacy.” Therefore, immediate follow-up and close coordination between psychiatric and primary care servi
总之,编辑汇编了一个连贯的文本,易于遵循和良好的记录,这可能是一个宝贵的资源,从业人员和研究人员与自杀患者工作。从历史上看,死亡的魅力已经存在了几个世纪。弗洛伊德的观点是,死亡驱力是生物恢复事物早期状态的一种冲动与100年前相比,我们现在对自杀的了解多了多少?只要还有病人自杀,那肯定是不够的。罗伯特·g·博塔,医学博士,密苏里州堪萨斯城密苏里大学
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引用次数: 3
Psychiatric Issues in Parkinson's Disease 帕金森病的精神问题
Pub Date : 2008-12-15 DOI: 10.4088/PCC.v10n0613b
M. Hasnain, W. Vieweg
Parkinson's disease is a progressive neurodegenerative disorder characterized by motor, somatic, and neuropsychiatric features. It leads to significant disability for the patient and burden for the caregivers. Providing care for patients with Parkinson's disease can be very challenging. A biopsychosocial approach best meets these difficulties, and editors Menza and Marsh provide a comprehensive practical guide to these ends. The book is divided into 4 sections. The first section offers an “introductory” overview to help the reader understand the clinical aspects of Parkinson's disease and its management. The information in this section is probably too basic for a neurologist but adequate for a nonneurologist clinician. The discussion on the etiology and pathogenesis of Parkinson's disease is brief but sufficient from a clinical perspective. Differentiating Parkinson's disease from other conditions with parkinsonian features is crucial for effective clinical management, patient and family education, and predicting clinical progression and outcome. A concise section in the first chapter tabulates the main features of other parkinsonian conditions to help in the differential diagnosis. Medical management of early Parkinson's disease is the focus of chapter 2. Antiparkinsonian medications are reviewed in this chapter with a brief section on the nonmedical treatments. The chapter guides prescribing practices and assessing patient's response to treatment. Motor complications related to disease progression and dopaminergic treatment are common in advanced Parkinson's disease. A concise discussion of these complications appears in chapter 3. An overview of the nonmotor somatic symptoms is offered in chapter 4. Section 2 focuses on cognitive dysfunction in Parkinson's disease. Cognitive impairment not meeting the threshold of dementia is common in patients with Parkinson's disease and can adversely affect their social, recreational, and occupational functioning. Because of its “subthreshold” nature, such cognitive impairment may not draw enough clinical attention. We were pleased to see a complete chapter on this topic in the book. Dementia associated with Parkinson's disease is the topic of the next chapter. After a concise and clinically relevant review of the definition of dementia and epidemiology of dementia in Parkinson's disease, the authors discuss assessment and management in more detail. Once Parkinson's disease dementia has developed, it is extremely difficult to differentiate it from dementia with Lewy bodies. The last chapter in this section reviews the differences between these 2 types of dementia and provides guidelines for clinical management of related issues that are found in both of these conditions. Section 3 addresses topics that one would expect based on the title of the book. Depression as a symptom is very common in patients with Parkinson's disease, but the true prevalence of the syndrome of major depression is hard to es
帕金森病是一种进行性神经退行性疾病,以运动、躯体和神经精神特征为特征。它会给病人带来严重的残疾,给护理人员带来负担。为帕金森氏症患者提供护理是非常具有挑战性的。生物心理社会方法最好地解决了这些困难,编辑门扎和马什为这些目的提供了一个全面的实用指南。这本书分为四个部分。第一部分提供了一个“介绍性”概述,以帮助读者了解帕金森病的临床方面及其管理。本节的信息对于神经科医生来说可能太基础了,但对于非神经科医生的临床医生来说已经足够了。关于帕金森氏病的病因和发病机制的讨论是简短的,但从临床角度来看是充分的。将帕金森病与其他具有帕金森特征的疾病区分开来,对于有效的临床管理、患者和家庭教育以及预测临床进展和预后至关重要。在第一章的一个简洁的部分列出了其他帕金森病的主要特点,以帮助鉴别诊断。早期帕金森病的医疗管理是第2章的重点。本章对抗帕金森病药物进行了回顾,并简要介绍了非药物治疗。本章指导处方做法和评估病人对治疗的反应。与疾病进展和多巴胺能治疗相关的运动并发症在晚期帕金森病中很常见。第3章对这些复杂情况作了简明的讨论。第4章概述了非运动性躯体症状。第2节关注帕金森病的认知功能障碍。未达到痴呆阈值的认知障碍在帕金森病患者中很常见,并可能对他们的社交、娱乐和职业功能产生不利影响。由于其“阈下”的性质,这种认知障碍可能不会引起足够的临床关注。我们很高兴在书中看到关于这个主题的完整章节。与帕金森病相关的痴呆是下一章的主题。在对痴呆的定义和帕金森病痴呆的流行病学进行了简明扼要的临床相关综述后,作者更详细地讨论了评估和管理。一旦帕金森氏症痴呆发展,就很难与路易体痴呆区分开来。本节的最后一章回顾了这两种痴呆症之间的差异,并提供了在这两种情况下发现的相关问题的临床管理指南。第3节讨论了人们根据书名所期望的主题。抑郁症作为一种症状在帕金森病患者中非常常见,但由于这种症状-综合征重叠,很难确定重度抑郁症综合征的真正患病率。本节的第一章讨论了这些问题,并为抑郁症的临床评估和管理提供了指导方针。帕金森病的焦虑障碍将在随后的章节中讨论。这些章节中的信息对于精神科医生来说可能太基础了,但对于非精神科医生来说却足够了。睡眠障碍在帕金森氏症患者中很常见,并可能导致其他症状,如白天疲劳、抑郁和精神病。本节的一章描述了帕金森病中可能的睡眠障碍的范围及其管理。对于《华尔街日报》的读者来说,控制帕金森氏症的最大挑战可能是既要治疗疾病本身,又要治疗由帕金森氏症引起的或与之并行的精神病。在这种情况下用于治疗神经生物学缺陷的药物可能会引发或加剧精神病。许多用于治疗精神病的药物可能会加重帕金森病。在这方面特别有价值的是题为“精神病”和“行为障碍”的章节。精神病的临床管理包括一系列一般步骤、非药物治疗和药物管理。在精神病的管理中特别重要的是早期发现,当帕金森病药物和行为管理的小调整或小剂量的新抗精神病药物可能会逆转或有效地控制精神病特征。新出现的报告发现乙酰胆碱酯酶抑制剂在帕金森综合征和破坏性行为患者中占有一席之地。行为障碍在帕金森氏症中很常见,给病人和看护人都带来了问题。 看护人的一项早期任务是确定导致破坏性行为的刺激是内部衍生的,比如在精神病中,还是通过与环境、工作人员和其他患者的相互作用而外部衍生的。作者引导我们解决这个难题。第四节也是最后一节使本书真正全面。这里,在“残疾”、“应对”、“个性问题”、“康复”、“长期护理和养老院问题”、“倡导和帕金森病社区:精神的真正胜利”和“护理”等章节标题下,讨论了与帕金森病相关的各种社会心理问题。本节增加了关于帕金森病患者护理的内容。总之,《帕金森病的精神病学问题:实用指南》提高了我们对这种疾病的总体理解,并为帕金森病的行为管理和药物治疗提供了见解。背景广泛的读者会发现这是他们图书馆的一个有价值的补充。西部地区综合卫生局,托马斯罗迪克爵士医院,斯蒂芬维尔,纽芬兰,加拿大。W. Victor R. Vieweg,医学博士,弗吉尼亚州里士满,弗吉尼亚联邦大学弗吉尼亚医学院
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引用次数: 1
Handbook of Medicine in Psychiatry. 精神病学医学手册。
Pub Date : 2008-10-15 DOI: 10.4088/PCC.V10N0512A
H. Goforth
The Handbook of Medicine in Psychiatry is directed toward psychiatrists who may not feel comfortable addressing medical conditions that often arise in psychiatric patients—especially lipid management, common infections, and electrolyte abnormalities. The book is well organized into a series of common medical conditions, and the chapters vary in content from directions on how to manage situations of less acuity to discussions of more complex differentials and needs for referral in higher acuity cases. Many chapters are further enhanced by the presence of flowcharts for quick reference and increased ease of use. The book is well written at an appropriate level for psychiatrists who may not have an internal medicine background, and the table of contents and index provide for easy accessibility. The text will find a primary home in the offices of psychiatrists who wish to take a more active role in the management of their patients’ medical conditions as well as those who may have suboptimal medical backup for routine complaints. While the Handbook of Medicine in Psychiatry will not replace the value of consulting physicians, psychiatrists will gain in medical knowledge such that it will be less likely for medical comorbidities to be underrecognized or suboptimally treated. The authors should be commended for their effort. Harold W. Goforth, M.D. Duke University Medical Center, Durham, North Carolina
《精神病学医学手册》是针对精神科医生的,他们可能对精神病人经常出现的医疗状况感到不舒服,尤其是血脂管理、常见感染和电解质异常。这本书是很好地组织成一系列常见的医疗条件,和章节的内容不同,从如何管理较不敏锐的情况下讨论更复杂的差异和需要转诊在较高的敏锐的情况。许多章节进一步加强了流程图的存在,以便快速参考和增加易用性。这本书写得很好,适合精神病医生谁可能没有内科背景,目录和索引提供了方便访问。文本将找到一个主要的家在精神病医生的办公室谁希望采取更积极的作用,在他们的病人的医疗条件的管理,以及那些谁可能有次优的医疗备份的日常投诉。虽然《精神病学医学手册》不会取代咨询医生的价值,但精神科医生将获得医学知识,从而使医学合并症不太可能被低估或治疗不理想。作者的努力应该受到赞扬。Harold W. Goforth,医学博士,杜克大学医学中心,北卡罗来纳州达勒姆
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引用次数: 3
Playing Sick? Untangling the Web of Munchausen by Proxy, Malingering, and Factitious Disorder 打生病吗?通过代理、装病和人为障碍来解开蒙乔森的网络
Pub Date : 2008-08-15 DOI: 10.4088/PCC.V10N0412A
Stephen M. Adams
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引用次数: 0
Child and Adolescent Clinical Psychopharmacology Made Simple. 儿童和青少年临床精神药理学变得简单。
Pub Date : 2008-08-15 DOI: 10.4088/PCC.V10N0412C
S. Wylie
There are many informative books available on the topic of psychopharmacology, but it is difficult to find concise and informative guidelines for treating children and adolescents. In addition, most psychiatric medications are not approved for use in children, and the U.S. Food and Drug Administration has placed limitations on using certain medications with this population. Practicing psychopharmacology with children and adolescents is not only more challenging clinically, it is also a much riskier practice clinically and medicolegally than practicing adult psychopharmacology; this book addresses these issues in a very precise manner. Dr. Preston, a well-known leader in teaching clinical psychopharmacology, has combined his knowledge with that of Dr. O'Neal (a psychiatrist) and Dr. Talaga (a psychiatric pharmacist) to produce a brief but informative practice guide for mental health and medical professionals alike. The book is well organized, with an introductory chapter that highlights current issues in prescribing psychiatric medications for children and adolescents followed by succinct chapters on each diagnostic category. This book also covers diagnoses such as autism, Tourette's disorder, and tic disorder, which are often omitted. I am not aware of a comparable book on the market that addresses treatment issues in an equally brief yet informative manner. This book addresses several pertinent issues in treating children and adolescents, including specific medical guidelines as well as often neglected yet vital contributory issues such as family dynamics, social variables, and cultural issues. Also included in this text are important concepts that might be overlooked by clinicians who are not used to treating this population; these include clinically significant changes in hepatic metabolism that accompany puberty, the need for concurrent psychotherapy with any psychopharmacology, the reality that parents who do not 100% endorse your treatment will often sabotage it, and the fact that clinicians who treat these patients will be prescribing mainly off-label and to a population that receives significant negative media coverage in regards to psychiatry. This book is easy to read and is based on both relevant clinical experience and sound research. In a book this size that covers a topic this big, there are bound to be omissions, and most of the omissions noted were secondary only to the depth allowed in a reference-based publication. However, I did discover some omissions that most likely should have been included. For example, very little coverage was given to the use of atypical antipsychotics for childhood bipolar disorder, which is out of step with current research and practice. Aside from mainly minor omissions, this book covered a very broad, difficult, and contentious psychiatric specialty in a very informative manner. I would recommend this book to my peers.
有许多关于精神药理学的信息丰富的书籍,但很难找到简明和信息丰富的指导方针来治疗儿童和青少年。此外,大多数精神科药物不被批准用于儿童,美国食品和药物管理局对儿童使用某些药物进行了限制。儿童和青少年的精神药理学实践不仅在临床上更具挑战性,而且在临床和医学法律上也比成人精神药理学实践更具风险;这本书以非常精确的方式论述了这些问题。普雷斯顿博士是临床精神药理学教学领域的知名领袖,他将自己的知识与奥尼尔博士(精神科医生)和塔拉加博士(精神科药剂师)的知识结合起来,为精神健康和医疗专业人员编写了一本简短但内容丰富的实践指南。这本书组织得很好,有一个导论章节强调了目前在为儿童和青少年开精神药物处方方面的问题,然后是每个诊断类别的简洁章节。这本书还包括诊断,如自闭症,妥瑞氏症,抽动障碍,这往往被省略。我不知道市场上有一本类似的书,以同样简短而翔实的方式解决治疗问题。这本书解决了几个相关的问题,在治疗儿童和青少年,包括具体的医疗指导方针,以及往往被忽视但重要的贡献问题,如家庭动态,社会变量和文化问题。还包括在这篇文章是重要的概念,可能会被忽视的临床医生谁不习惯治疗这一人群;这些包括伴随青春期的肝代谢的临床显著变化,需要与任何精神药理学同时进行心理治疗,不100%支持你的治疗的父母往往会破坏它的现实,以及治疗这些患者的临床医生将主要是在标签外开处方,并且对一个在精神病学方面接受大量负面媒体报道的人群。这本书很容易阅读,是基于相关的临床经验和健全的研究。在这么大的一本书中,涵盖了这么大的主题,必然会有遗漏,而且大多数遗漏都是次要的,只有在基于参考文献的出版物中允许的深度。然而,我确实发现了一些很可能应该包括在内的遗漏。例如,对儿童双相情感障碍使用非典型抗精神病药物的报道很少,这与目前的研究和实践不一致。除了主要的小遗漏之外,这本书以一种非常翔实的方式涵盖了一个非常广泛、困难和有争议的精神病学专业。我会把这本书推荐给我的同龄人。
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引用次数: 3
The Early Course of Schizophrenia. 精神分裂症的早期病程。
Pub Date : 2008-08-15 DOI: 10.4088/PCC.V10N0412B
J. Goeb
Schizophrenia is a chronic psychiatric disease that represents an immense amount of individual and familial suffering and an important social burden. Early explanations involved various unique etiologies (among others: a virus, a single gene, or, unfairly, the mother), but the last decades of research have recognized schizophrenia as a multifactorial disease. The Early Course of Schizophrenia, edited by Tonmoy Sharma, M.D., and Philip D. Harvey, Ph.D., and written by experts in the field, addresses the most pressing questions in the pathogenesis and treatment of schizophrenia, focusing on the strongest evidence to date with great clarity. The first section, “Schizophrenia in the Premorbid Period,” begins with a discussion of some of the key evidence supporting the neurodevelopmental hypothesis of schizophrenia. The neurodevelopmental hypothesis distinguishes several periods of this illness, extending from vulnerability to risk factors to the definite clinical diagnosis. These include an early premorbid period, associated with nonspecific abnormalities, and the prodromal period, retrospectively assessed as a time of various symptoms and difficulties (including many that are hardly specific to schizophrenia, such as depressed mood, anxiety, social withdrawal, irritability, and aggressive behavior; suicidal ideation and attempts; and substance use). These periods precede the onset of frank psychotic symptoms (hallucinations, delirious thoughts, and negative symptoms). This widely accepted model involves a developing brain, with genetic vulnerabilities interacting with environmental insults that may occur both in early life (when risk factors may include prenatal exposure or obstetric complications) and during adolescence or early adulthood (when risk factors may include pubertal changes, substance use, or the process in adolescence that requires coping with the new identity, sexuality oriented toward other people, and autonomy from the parents). The interactions between these different kinds of internal and external risk factors are best illustrated by the example of one person's believing that others are thinking badly about or laughing at him, resulting in social withdrawal; nonattendance at school, university, or work; and suspiciousness and altered behavior toward family and friends. Precocious therapeutic interventions may permit the patient to benefit from social integration and avoid psychiatric chronicity. That outcome requires both treating the disease intensively in the early phases and respecting what may retrospectively appear as a transitory adaptation to a stressful period in the patient's life. “Schizophrenia in the Premorbid Period” provides, interestingly, a synthetic description of intellectual and cognitive functioning before and at the onset of the first episode, stressing that, for a subgroup of patients, cognitive deficits (executive functions, working memory, attention, and abstract reasoning) are already evident m
精神分裂症是一种慢性精神疾病,给个人和家庭带来巨大痛苦,也是一种重要的社会负担。早期的解释涉及各种独特的病因(其中包括:病毒,单一基因,或者不公平的是,母亲),但最近几十年的研究已经认识到精神分裂症是一种多因素疾病。《精神分裂症早期病程》由Tonmoy Sharma医学博士和Philip D. Harvey博士编辑,由该领域的专家撰写,阐述了精神分裂症发病机制和治疗中最紧迫的问题,重点关注迄今为止最有力的证据,非常清晰。第一部分“病前期的精神分裂症”首先讨论了支持精神分裂症神经发育假说的一些关键证据。神经发育假说区分了这种疾病的几个时期,从易感性到危险因素再到明确的临床诊断。这些包括与非特异性异常相关的早期病前期和前驱期,前驱期被回顾性评估为各种症状和困难(包括许多非精神分裂症特有的症状,如抑郁情绪、焦虑、社交退缩、易怒和攻击行为;自杀意念和企图;和物质使用)。这些时期先于明显的精神病症状(幻觉、神志不清的思想和阴性症状)的出现。这一被广泛接受的模型涉及到发育中的大脑,其遗传脆弱性与可能发生在生命早期(风险因素可能包括产前暴露或产科并发症)和青春期或成年早期(风险因素可能包括青春期的变化、物质使用或青春期需要应对新身份的过程、对他人的性取向以及来自父母的自主性)的环境损害相互作用。这些不同类型的内部和外部风险因素之间的相互作用最好地说明了一个例子:一个人认为别人对他的看法很差或嘲笑他,从而导致社交退缩;旷课,旷课:在学校、大学或工作中不出勤;以及对家人和朋友的怀疑和行为改变。性早熟治疗干预可以使患者受益于社会融合,避免精神疾病的慢性化。要取得这样的结果,既需要在早期阶段对疾病进行密集治疗,又需要尊重可能在事后看来是对患者生活中压力时期的短暂适应。有趣的是,《病前期的精神分裂症》对首次发作前和发作时的智力和认知功能进行了综合描述,并强调,对于一个亚组患者,认知缺陷(执行功能、工作记忆、注意力和抽象推理)在精神分裂症的临床诊断前多年就已经很明显,并且在精神病症状发作后的最初几年里表现稳定。这些被认为是精神分裂症的核心特征的认知异常,将在下一节“第一阶段精神分裂症”中得到发展,它们是第三节最后一章的主题,这一章涉及不同形式的“早期精神分裂症的治疗”。最后一节提供了一个综合治疗方案的概述,重点关注当前的症状和行为或残疾,以及旨在延迟、改善甚至预防精神障碍进展的治疗。有关于早发性和晚发性(一个不精确的术语)精神分裂症的章节,精神分裂症的早期课程推荐给所有关心精神疾病的医生。然而,如果把注意力集中在疾病的早期阶段,就会导致一种错觉,即精神疾病不会在患者的整个生命周期中持续下去,那么就会失去重点。精神分裂症的早期病程确实解决了维持治疗、复发预防和治疗依从性等持续存在的问题。
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引用次数: 0
Understanding Depression: A Complete Guide to Its Diagnosis and Treatment, 2nd ed. 理解抑郁症:一个完整的指南,其诊断和治疗,第二版。
Pub Date : 2008-06-16 DOI: 10.4088/PCC.V10N0313C
Jeff Mitchell
This book is written for laypeople who want to understand mood disorders from a biological perspective. It could also be used by primary care physicians for purposes of patient education. This is the second edition; the first was published in 1993.1 Both of the authors are pioneers in biological psychiatry. Dr. Klein is an emeritus professor at the New York State Psychiatric Institute. Dr. Wender is an emeritus professor at the University of Utah School of Medicine and a lecturer at Harvard Medical School. The book contains chapters on recognizing depression (with a helpful self-rating questionnaire), distinguishing depression from bipolar mood disorders, causes of mood disorders, diagnosis and treatment of depression, a brief guide to psychophar-macologic drugs, illnesses related to depression, and how to get help. This is a readable book for laypersons and includes excellent case examples. The information about antidepressants is up-to-date and informative. Psychiatrists and primary care physicians regularly have to contend with public misinformation about antidepressants; the chapter on these medications would go a long way toward properly educating patients about the risks and benefits of these drugs. There are also sections on sleep aids, antipsychotics, anticonvulsants, and benzodiazepines. Herbal treatments are also addressed. This publication strongly focuses on the biological model of depression, which has been the authors' lifetime area of study. They have less expertise on non-biological models of treatment, and it shows in this book. Drs. Klein and Wender acknowledge the relationship between biological predisposition and life stress, though they heavily favor medical treatment over psychotherapy. They incorrectly state that there is little evidence that cognitive-behavioral therapy is more effective than placebo in treating depression (page 105). Nor do the authors touch upon lifestyle issues such as maintaining active schedules and exercise. Readers might also get the impression that psychiatrists are the only individuals qualified to treat depression. It is well known, particularly in non-urban settings, that antidepres-sants are primarily prescribed by primary care physicians. With the shortcomings aside, I would recommend this book for any layperson looking for authoritative information about the biology of mood disorders.
这本书是为那些想从生物学角度理解情绪障碍的外行人写的。它也可以被初级保健医生用于病人教育的目的。这是第二版;第一篇发表于1993年。两位作者都是生物精神病学的先驱。克莱因博士是纽约州精神病学研究所的名誉教授。温德博士是犹他大学医学院的名誉教授和哈佛医学院的讲师。这本书包含了认识抑郁症的章节(有一个有用的自评问卷),区分抑郁症与双相情绪障碍,情绪障碍的原因,抑郁症的诊断和治疗,精神药物的简要指南,抑郁症相关的疾病,以及如何获得帮助。这是一本外行可读的书,包括优秀的案例。关于抗抑郁药的信息是最新的,信息丰富。精神科医生和初级保健医生经常不得不与公众对抗抑郁药的错误信息作斗争;关于这些药物的章节将对正确教育患者这些药物的风险和益处大有帮助。书中也有关于助眠药、抗精神病药、抗惊厥药和苯二氮卓类药物的章节。草药治疗也得到了解决。这篇文章强烈关注抑郁症的生物学模型,这是作者一生的研究领域。他们在非生物治疗模式方面缺乏专业知识,这在这本书中有所体现。Drs。克莱因和温德承认生理倾向和生活压力之间的关系,尽管他们更倾向于药物治疗而不是心理治疗。他们错误地指出,几乎没有证据表明认知行为疗法在治疗抑郁症方面比安慰剂更有效(第105页)。作者也没有触及生活方式的问题,如保持积极的时间表和锻炼。读者可能还会有这样的印象:精神病医生是唯一有资格治疗抑郁症的人。众所周知,特别是在非城市环境中,抗抑郁药主要是由初级保健医生开的。撇开缺点不谈,我会向任何寻找有关情绪障碍生物学权威信息的外行人推荐这本书。
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引用次数: 2
Psychotherapy for Depression in Older Adults 老年人抑郁症的心理治疗
Pub Date : 2008-06-16 DOI: 10.4088/PCC.V10N0313A
B. Cairns
Psychotherapy for Depression in Older Adults is the first book in the Wiley Series in Clinical Geropsychology, which is directed primarily at psychologists who are currently, or seeking to begin, working with an aging patient population. As the authors are quick to point out, the demographic of the American population, regardless of ethnic group or socioeconomic status, is shifting toward a greater geriatric representation as the “baby boomer” cohort comes of retirement age. In the face of this aging population, however, there is a lack of professionals trained in the mental health needs of the elderly.
《老年人抑郁症的心理治疗》是Wiley临床老年心理学系列的第一本书,主要针对那些目前正在或试图开始与老年患者群体合作的心理学家。正如作者迅速指出的那样,随着“婴儿潮”一代进入退休年龄,美国人口的人口结构,无论种族或社会经济地位如何,都在向老年人的比例增加转变。然而,面对人口老龄化,缺乏受过老年人心理健康需求培训的专业人员。
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引用次数: 14
期刊
The Primary Care Companion To The Journal of Clinical Psychiatry
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