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Quality of Life in Children with Acyanotic Congenital Heart Disease in Dr. Soetomo General Hospital, Surabaya, Indonesia 印度尼西亚泗水Dr. Soetomo总医院无矢性先天性心脏病患儿的生活质量
Pub Date : 2022-04-06 DOI: 10.20473/ccj.v3i1.2022.1-8
Salsabila Fabianca Alsaid, Taufiq Hidayat, H. Soebroto
Abstract: Acyanotic congenital heart disease is a disease that affects the patient physically and psychologically result in the patient not being able to carry out his life normally. As a result, patients will feel lonely, rejected, and isolated from society which makes social integration more difficult. The picture of quality of life in acyanotic CHD patients can be used as a therapeutic evaluation material to improve quality of life. Material and Methods: This study used descriptive analytic method with total sampling. The variable studied was quality of life using Pedsql Inventory 3.0 Cardiac Module questionnaire to the patients aged 2-18 years who were treated at Dr. Soetomo General Hospital Surabaya in 2019—2020. Results: 74 Acyanotic CHD patients (left to right shunt) obtained an average quality of life of 73.89 ± 9.79 with low-value aspects, namely Heart Problems and Therapy I (72.92 ± 18.20), Cognitive (59.53 ± 18.40), and Communication (71.40 ± 24.21). There was a significant difference in the type of combination diagnosis compared with other types with a significance of 0.014 (p <0.05). Conclusion: Aspects that have a negative impact on the patient's quality of life are Heart Problems and Therapy I, Cognitive, and Communication. The Combination type is a diagnosis with the lowest quality of life compared to other types. 
摘要:无氰型先天性心脏病是一种影响患者生理和心理,导致患者不能正常进行生活的疾病。因此,患者会感到孤独,被排斥,与社会隔离,这使得社会融入更加困难。无肺型冠心病患者的生活质量图可作为改善生活质量的治疗性评价资料。材料与方法:本研究采用全抽样描述性分析方法。研究变量为2019-2020年在泗水Soetomo综合医院接受治疗的2-18岁患者的生活质量,采用Pedsql Inventory 3.0 Cardiac Module问卷。结果:74例无肺型冠心病(左向右分流)患者平均生活质量为73.89±9.79,低价值方面分别为心脏问题及治疗I(72.92±18.20)、认知(59.53±18.40)、沟通(71.40±24.21)。合并诊断的分型与其他分型比较,差异有统计学意义(p <0.05),为0.014。结论:对患者生活质量有负面影响的方面是心脏问题和治疗I、认知和沟通。与其他类型相比,合并型是一种生活质量最低的诊断。
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引用次数: 0
Clinical Characteristics and Profile of Heart Failure Patients at dr. Ramelan Navy Hospital in 2020 2020年Ramelan海军医院心力衰竭患者临床特征及概况
Pub Date : 2022-03-31 DOI: 10.20473/ccj.v3i1.2022.9-14
I. Hermawan, Ken Christian Kawilarang, F. Hartono
Background: Heart failure (HF) is a global pandemic affecting at least 26 million people worldwide and is increasing in prevalence. It has been associated with a high rate of readmissions and prolonged hospitalizations. There were few publications in Indonesia that described the characteristics and length of hospital stay of heart failure patients.Aims: To obtain data and describe the clinical characteristics and profile of heart failure patients hospitalized at dr. Ramelan Navy Hospital in 2020.Methods and Results: A cross sectional study was done using secondary data from patients’ medical records in dr. Ramelan Navy Hospital admitted during 2020. Data were then calculated and presented further. Based on the medical records, 121 heart failure patients were included in the study. Median age was 56 years old, 58,7% were men. Median length of stay was 6 days for all patients. 51.2% patients admitted to hospital with NYHA FC III. When patients were admitted to hospital, median systolic blood pressure was 124 mmHg and pulse was 91 beats per minute. Peripheral edema was shown in 67,8% of patients, hypertension in 49,6%, diabetes mellitus in 24,8%, ischemic heart disease in 52,9%. 6.6% of total patients treated in hospital died.Conclusion: Median length of stay for heart failure patients at dr. Ramelan Navy Hospital was 6 days. Most patients were men with median age of 56 years old.Keywords: clinical characteristic; demographic; heart failure
背景:心力衰竭(HF)是一种影响全球至少2600万人的全球性流行病,其患病率正在上升。它与高再入院率和长时间住院有关。在印度尼西亚,很少有出版物描述心力衰竭患者的特征和住院时间。目的:获取数据并描述2020年在dr. Ramelan海军医院住院的心力衰竭患者的临床特征和概况。方法和结果:利用2020年Ramelan海军医院住院患者病历的二次数据进行了横断面研究。然后对数据进行计算并进一步呈现。根据医疗记录,121名心力衰竭患者被纳入研究。中位年龄56岁,58.7%为男性。所有患者的中位住院时间为6天。51.2%的患者因NYHA FC III住院。患者入院时,中位收缩压为124 mmHg,脉搏为每分钟91次。外周水肿占67.8%,高血压占49.6%,糖尿病占24.8%,缺血性心脏病占52.9%。6.6%的住院患者死亡。结论:心力衰竭患者在拉梅兰海军医院的平均住院时间为6天。大多数患者为男性,中位年龄56岁。关键词:临床特征;人口结构;心脏衰竭
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引用次数: 0
Simultaneous Transcatheter Pulmonary Balloon Valvuloplasty and Atrial Septal Defect Closure in Adult Patient 经导管肺动脉球囊瓣膜成形术与房间隔缺损合并术的研究
Pub Date : 2022-03-31 DOI: 10.20473/ccj.v3i1.2022.32-39
D. E. Wardhani, Eka Prasetya Budi Mulia, D. Rachmi
Background: Percutaneous pulmonary balloon valvuloplasty (PBV) has become the first choice of management in patients with valvular pulmonary stenosis, while transcatheter closure in secundum atrial septal defect (ASD) is an alternative therapy besides surgical closure. The combination of PBV and transcatheter ASD closure is an action that is possible to do, but rarely done.Case Illustration: We present a case of 26-year-old woman with severe pulmonary stenosis and secundum ASD.  Echocardiographic examination revealed the presence of severe pulmonary stenosis (mean gradient 99.19 mmHg) and defects in the intra atrial septum (with a size of 1.3 cm). Cardiac catheterization revealed right ventricular pressure of 160 mmHg. This patient then successfully corrected with both procedures ASD closure and PBV simultaneously. Discussion: These procedures have high feasibility, good safety, and shows good effectiveness. There were no complications during the procedures, and a satisfying immediate outcome was obtained.Conclusion: Pulmonary stenosis and atrial septal defects are rare forms of congenital heart disease. Transcatheter pulmonary balloon valvuloplasty and atrial septal defect closure performed simultaneously are promising alternatives, apart from surgical correction.
背景:经皮肺球囊瓣膜成形术(PBV)已成为瓣膜性肺狭窄患者的首选治疗方法,而经导管闭合术治疗继发性房间隔缺损(ASD)是除手术闭合术外的另一种治疗方法。PBV联合经导管ASD闭合是一种可行的方法,但很少被采用。病例说明:我们报告一例26岁女性严重肺狭窄伴继发性ASD。超声心动图检查发现严重肺动脉狭窄(平均梯度99.19 mmHg),房间隔缺损(大小1.3 cm)。心导管检查显示右心室压160 mmHg。该患者随后成功地同时进行了ASD闭合和PBV两种手术。讨论:该方法可行性高,安全性好,效果好。手术过程中无并发症发生,术后即刻效果满意。结论:肺动脉狭窄和房间隔缺损是罕见的先天性心脏病。经导管肺球囊瓣膜成形术和房间隔缺损关闭同时进行是有希望的选择,除了手术矫正。
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引用次数: 0
A Patient with Acute Myocardial Infarction who Experienced Mortality due to Ventricular Septal Rupture: A Case Report 急性心肌梗死患者因室间隔破裂死亡1例
Pub Date : 2022-03-31 DOI: 10.20473/ccj.v3i1.2022.46-51
Romi Ermawan
Ventricular septal rupture (VSR) is one of the rare complications of acute myocardial infarction (AMI). Although the incidence decreased in percutaneous coronary intervention (PCI) era, the mortality rate remained extremely high. We report a case of an AMI patient who developed a post-fibrinolytic VSR, which was confirmed by echocardiography. Although rescue PCI had been performed, the clinical condition did not improve because he was also having coronary slow flow (CSF). Then he fell into cardiogenic shock and acute lung edema, and died. The main key to dealing with VSR is to reduce afterload so that the left-to-right bypass flow can be reduced in order to maintain the adequate LV stroke volume. In addition to pharmacological therapy, mechanical supportive therapy and correction of VSR both surgically or transcatheterly are required. However, AMI patients with VSR still have a poor prognosis even with the optimal treatment. 
室间隔破裂是急性心肌梗死(AMI)的罕见并发症之一。虽然在经皮冠状动脉介入治疗(PCI)时代发病率有所下降,但死亡率仍然很高。我们报告一例AMI患者发展为纤溶后VSR,经超声心动图证实。虽然进行了抢救PCI,但由于患者同时出现冠状动脉慢血流(CSF),临床情况没有改善。然后他陷入心源性休克和急性肺水肿,死亡。处理VSR的主要关键是减少后负荷,以减少左向右旁路流量,以保持足够的左室行程容量。除了药物治疗外,机械支持治疗和VSR的手术或经导管矫正是必要的。然而,AMI合并VSR患者即使采用最佳治疗方法,预后仍较差。
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引用次数: 0
The Exacerbation of Lutembatcher Syndrome in The Setting of COVID-19 infection: A Rare Case Report COVID-19感染背景下Lutembatcher综合征的加重:罕见病例报告
Pub Date : 2022-03-31 DOI: 10.20473/ccj.v3i1.2022.22-31
A. W. Nugraha, Y. Azmi, T. T. E. Lusida, Lisca Namretta, Nida A. Suyani, F. S. Laitupa
Lutembatcher syndrome is a rare cardiac condition characterized by a combination of the atrial septal defect (ASD; congenital or iatrogenic) and mitral stenosis (MS; congenital or acquired). Patients with Lutembatcher syndrome and adults with congenital heart disease (ACHD) in general may be at high risk when accompanied by coronavirus disease 2019 (COVID-19). Since there is no published study on the impact of COVID-19 on ACHD, little is known about management strategies in this subset of patients. Herein, we report a young adult female presented with abdominal discomfort, swollen legs, fever, cough, and dyspnea. The patient had developed palpitation and exercise intolerance five years ago but paid it no attention. Echocardiography revealed large secundum type ASD with severe MS (Wilkins score of eight) and a nasopharyngeal swab confirmed SARS-COV-2 infection. The patient was diagnosed with Lutembacher syndrome and COVID-19. Intensive treatment was given to relieve symptoms due to heart failure and to treat COVID-19 pneumonia. Patients with Lutembatcher syndrome are at a higher risk of being infected with COVID-19 and manifest into severe infections. Therefore, determining the risk of infection and the severity of COVID-19 in ACHD patients are required during the pandemic.
Lutembatcher综合征是一种罕见的心脏疾病,其特征是房间隔缺损(ASD;先天性或医源性)和二尖瓣狭窄(多发性硬化症;先天性或后天)。一般而言,Lutembatcher综合征患者和成人先天性心脏病(ACHD)患者在伴有2019冠状病毒病(COVID-19)时可能处于高危状态。由于没有关于COVID-19对ACHD影响的已发表研究,因此对这部分患者的管理策略知之甚少。在此,我们报告一位年轻的成年女性,表现为腹部不适,腿部肿胀,发烧,咳嗽和呼吸困难。患者五年前出现心悸和运动不耐受,但没有引起注意。超声心动图显示大面积继发性ASD伴严重多发性硬化症(威尔金斯评分为8分),鼻咽拭子确诊为SARS-COV-2感染。患者被诊断为Lutembacher综合征和COVID-19。加强治疗,缓解心力衰竭症状,治疗COVID-19肺炎。Lutembatcher综合征患者感染COVID-19并表现为严重感染的风险较高。因此,在大流行期间需要确定ACHD患者的感染风险和COVID-19的严重程度。
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引用次数: 0
Doubly Committed Subarterial Ventricular Septal Defect Coexisted with Ruptured Aneurysm of The Right Sinus Valsava 双重动脉下室间隔缺损合并右瓣膜窦动脉瘤破裂
Pub Date : 2022-03-31 DOI: 10.20473/ccj.v3i1.2022.40-45
I. Maghfirah, R. Romdoni
Sinus of Valsalva aneurysms (SVAs) are uncommon cardiac abnormalities and most of them are in congenital origin. Some patients may have SVAs that concomitant with ventricular septal defect (VSD). Here, we reported case of a 37-year-old male presented with worsening exertional dyspnoea. Thrills and loud continuous murmur along the left sternal border were discovered during physical examination. Echocardiogram displayed ruptured sinus of valsalva aneurysm to the right ventricle along with supracristal ventricular septal defect (VSD). The patient underwent surgical correction with patch repair and aortic valve replacement. Most cases of SVAs were originated from right coronary sinus. They usually ruptured into right ventricle. Ventricular septal defects often coexisted with this condition. Echocardiography provided a complete evaluation of such cases and prohibited missed diagnosis of other coexistent congenital heart defects.
瓣膜窦动脉瘤是一种罕见的心脏异常,大多数是先天性的。有些患者可能伴有室间隔缺损(VSD)。在这里,我们报告了一个37岁的男性表现为加重的用力性呼吸困难。体格检查时发现左胸骨边界有震颤和持续的大杂音。超声心动图显示右心室瓣膜动脉瘤窦破裂并伴有室间隔缺损(VSD)。患者接受了补片修复和主动脉瓣置换术的手术矫正。sva多起源于右冠状动脉窦。它们通常破裂进入右心室。室间隔缺损常与此病共存。超声心动图提供了完整的评估这些病例,并禁止漏诊其他共存的先天性心脏缺陷。
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引用次数: 0
Correlation Between Bioelectrical Impedance Analysis-Measured Body Fat, Body Mass Index and Waist Circumference with Cardiovascular Risk Factors in Acute Coronary Syndrome Patients 生物阻抗分析-测量体脂、体质量指数和腰围与急性冠状动脉综合征患者心血管危险因素的相关性
Pub Date : 2021-09-30 DOI: 10.20473/CCJ.V2I2.2021.51-58
Imam Mahbub Zam Zami, B. Pikir
Estimation of fat using bioelectrical impedance analysis (BIA) is thought to be a more predictive measure of cardiovascular (CV) risk assessment than body mass index (BMI) or waist circumference (WC). Percent body fat as measured using BIA (BIA-BF%) is independently associated with future cardiovascular events namely acute myocardial infarction, ischemic heart disease. This study is conducted to determine the correlation between body fat which consists of BIA-BF%, percentage of subcutaneous adipose tissue (SAT) and visceral fat level (Visceral Adipose Tissue/VAT) measured using BIA device, BMI and WC with CV risk factors (blood pressure, blood glucose level, LDL, HDL, TG, total cholesterol, HbA1c and serum fibrinogen) in patients with acute coronary syndrome (ACS). Material and Methods : This study used a cross-sectional correlation analysis. Sample was 70 ACS patients that match with inclusion criteria. Results : We found significant correlations between BIA-BF% with diastolic blood pressure, TG, and total cholesterol (r = 0.246, r = 0.250, r = 0.348 respectively; p <0.05). There was a significant correlation between VAT with diastolic blood pressure, LDL, TG, total cholesterol, HbA1c, and fibrinogen (r = 0.299, r = 0.306, r = 0.278, r = 0.265, r = 0.292, r = 0.330 respectively, p <0.05). There was a significant correlation between the percentage SAT and HDL levels (r = 0.318; p <0.05). We found no correlation between BMI and WC with blood pressure, LDL, HDL, TG, blood glucose, HbA1c and fibrinogen levels in ACS patients. Conclusion: VAT and BIA-BF% correlate with several cardiovascular risk factors better than BMI and WC. Body fat examination using BIA may be done to manage risk factors in ACS patients.
与体重指数(BMI)或腰围(WC)相比,利用生物电阻抗分析(BIA)估算脂肪被认为是一种更能预测心血管(CV)风险的方法。用BIA (BIA- bf %)测量体脂百分比与未来心血管事件(即急性心肌梗死、缺血性心脏病)独立相关。本研究旨在确定急性冠状动脉综合征(ACS)患者体脂(BIA- bf %、皮下脂肪组织百分比(SAT)和使用BIA装置测量的内脏脂肪水平(内脏脂肪组织/VAT)、BMI和WC与CV危险因素(血压、血糖水平、LDL、HDL、TG、总胆固醇、HbA1c和血清纤维蛋白原)之间的相关性。材料与方法:本研究采用横断面相关分析。样本为70例符合纳入标准的ACS患者。结果:BIA-BF%与舒张压、TG、总胆固醇有显著相关性(r = 0.246, r = 0.250, r = 0.348;p < 0.05)。VAT与舒张压、LDL、TG、总胆固醇、HbA1c、纤维蛋白原有显著相关性(r = 0.299、r = 0.306、r = 0.278、r = 0.265、r = 0.292、r = 0.330, p <0.05)。SAT百分比与HDL水平有显著相关性(r = 0.318;p < 0.05)。我们发现BMI和WC与ACS患者的血压、LDL、HDL、TG、血糖、HbA1c和纤维蛋白原水平没有相关性。结论:VAT和BIA-BF%与若干心血管危险因素的相关性优于BMI和WC。使用BIA进行体脂检查可以管理ACS患者的危险因素。
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引用次数: 1
A Case of Malignant Course of Right Coronary Artery: Frequent Angina in Young Person 青年人右冠状动脉恶性病程:常发心绞痛1例
Pub Date : 2021-09-30 DOI: 10.20473/CCJ.V2I2.2021.90-94
S. Purwowiyoto, S. P. Surya
Introduction:Congenital anomalous coronary artery is a rare condition, but it might be the biggest pitfall for cardiologist. It might be silent until the patient reach young adult and has high intensity activity. Symptomatic anomalous course of coronary artery has wide spectrum from asymptomatic until the lethal one.Case Ilustration: We present a case of young adult with activity-triggered atypical chest pain and diagnose with anomalous origin of right coronary artery (RCA) from the left coronary sinus with inter-arterial course between the aorta and the main pulmonary artery that was detected by CT coronary angiography. This anomaly has been called malignant course RCA.Discussion:Coronary artery anomaly is a congenital condition. Most of the cases are remain asymptomatic. This condition also one of the most cause for sudden cardiac death because the coronary artery examination is not regularly done. Nevertheless, during high intense activity, it will be symptomatic and might be lethal.Conclusion:Diagnose coronary artery anomalies might be tricky and cardiologist must be aware with this. More devastating, no firm guideline in treatment of right anomalous coronary artery from opposite sinus.
简介:先天性冠状动脉异常是一种罕见的疾病,但它可能是心脏病专家最大的陷阱。它可能是沉默的,直到患者达到年轻的成年人,并有高强度的活动。冠状动脉症状性异常过程从无症状到致死性异常具有广泛的谱系。病例说明:我们报告一位年轻的成年人,因活动引发的非典型胸痛,并诊断为右冠状动脉异常起源(RCA),从左冠状动脉窦,并在主动脉和肺动脉主动脉之间的动脉间路线,通过CT冠状动脉造影检测。这种异常被称为恶性病程RCA。讨论:冠状动脉异常是一种先天性疾病。大多数病例仍无症状。由于冠状动脉检查不定期,这种情况也是心源性猝死的最主要原因之一。然而,在高强度活动期间,它将出现症状并可能致命。结论:冠状动脉异常的诊断可能是一个棘手的问题,心脏科医生必须意识到这一点。更严重的是,在治疗右冠状动脉异位时,没有明确的指导方针。
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引用次数: 0
Case Presentation - Biventricular Hypertrophy and Valvular Pulmonary Stenosis in Adult Patient with Noonan Syndrome: A Rare Case 病例介绍-成人Noonan综合征患者双心室肥厚和瓣膜性肺动脉狭窄:一例罕见病例
Pub Date : 2021-09-30 DOI: 10.20473/ccj.v2i2.2021.77-83
Tinton Pristianto, R. A. Fagi
Introduction: Noonan syndrome (NS) is a genetic disorder often accompanied by multiple congenital abnormalities. The prevalence of NS at live birth has been reported as one in 1000-2500 individuals. About 80% of patients with Noonan syndrome have abnormalities in the cardiovascular system.Case presentation:41-year-old Javanese male presented with chief complaint shortness of breath.  His Body Mass Index (BMI) was 18,3. He had an oval-shaped face with a short neck, thin hair, and prominent nasolabial fold. Echocardiography showed biventricular hypertrophy alongside pulmonary valve stenosis, pulmonary regurgitation and minimal pericardial effusion. Discussion: In 1962, Jacqueline Noonan, a pediatric cardiologist, identified 9 patients whose faces were very similar, had short stature, significant chest deformities, and with pulmonary stenosis. Noonan syndrome is a relatively common non-chromosomal syndrome that is similar to the phenotype of Turner's syndrome and presents with cardiovascular malformations. Adult with NS has distinctive facial features such as ptosis, wide eyes, low posterior rotation of ears and helical thickening, and a wide neck.Pulmonary stenosis is the most common heartdefect found in NS, besides HCM isalsoquitecommon inabout20% of patients. We reported a case of a patient with typical characteristics of NS such as pulmonary valve stenosis accompanied by biventricular ventricular hypertrophyand its typical face who survived through adulthood.Conclusion: Syndrome Noonan in the adult is quite rare and difficult to diagnose. We reported a case of an adult man with facial appearance and echocardiographic findings identical with Noonan Syndrome.
努南综合征(NS)是一种遗传性疾病,常伴有多种先天性异常。据报道,活产新生儿的NS患病率为1 / 1000-2500。大约80%的努南综合征患者有心血管系统异常。病例介绍:41岁爪哇男性,主诉为呼吸短促。他的身体质量指数(BMI)为18.3。他长着一张椭圆形的脸,脖子短,头发稀疏,鼻唇沟突出。超声心动图显示双心室肥厚伴肺动脉瓣狭窄,肺返流和少量心包积液。讨论:1962年,儿科心脏病专家杰奎琳·努南(Jacqueline Noonan)发现了9名面部非常相似、身材矮小、明显胸部畸形和肺狭窄的患者。努南综合征是一种比较常见的非染色体综合征,与特纳综合征的表型相似,表现为心血管畸形。成人NS具有明显的面部特征,如上睑下垂,眼睛大,耳朵后旋低,螺旋增厚,颈部宽。肺狭窄是NS中最常见的心脏缺陷,此外HCM也很常见,约占20%。我们报告了一例具有典型的NS特征的患者,如肺动脉瓣狭窄伴双心室肥厚及其典型的面部,并存活至成年期。结论:成人努南综合征是一种罕见且诊断困难的疾病。我们报告了一例成年男性的面部外观和超声心动图结果与努南综合征相同。
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引用次数: 0
Infective Endocarditis: A Case with Prolonged Fever 感染性心内膜炎伴持续发热1例
Pub Date : 2021-09-30 DOI: 10.20473/ccj.v2i2.2021.84-89
M. Prismadani, Agus Subagjo
Infective endocarditis (IE) is associated with a high rate of mortality and morbidity in patients with anomalies of heart valves. We present a case of a 23-year-old male known to have severe mitral regurgitation (MR) with a history of prolonged fever for 5 months. According to The Modified Duke Criteria, clinical sign and symptoms fulfilled one major criterion (echocardiography finding of vegetation on mitral valve) and three minor (fever of at least 380 Celsius, valvular heart disease as a predisposing heart condition, and positive blood culture for Lactococcus sp. and Pediococcus sp.) considered as definite IE. Fever is one of the most common symptoms of IE (>90% of cases). Patient with prolonged fever and structural abnormality of heart valve should be considered for acute or subacute of IE. Establishing an diagnosis of IE and appropriate antibiotic therapy will improve the patient's clinical condition, and reduce morbidity and mortality.
感染性心内膜炎(IE)与心脏瓣膜异常患者的高死亡率和发病率相关。我们报告一个23岁的男性病例,已知有严重的二尖瓣反流(MR),并有持续发烧5个月的历史。根据修改后的Duke标准,临床体征和症状满足一个主要标准(超声心动图发现二尖瓣上的植被)和三个次要标准(至少380摄氏度的发烧,瓣膜性心脏病作为易感心脏疾病,乳酸球菌和Pediococcus sp血培养阳性)被认为是明确的IE。发烧是IE最常见的症状之一(90%的病例)。急性或亚急性IE应考虑有持续发热和心脏瓣膜结构异常的患者。建立IE的诊断和适当的抗生素治疗将改善患者的临床状况,并降低发病率和死亡率。
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引用次数: 1
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Cardiovascular and Cardiometabolic Journal (CCJ)
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