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Phytochemical Profile and Anticancer Activity from Medicinal Plants Against Melanoma Skin Cancer: A Review 药用植物抗黑色素瘤皮肤癌的植物化学特征及抗癌活性研究进展
Q1 Earth and Planetary Sciences Pub Date : 2022-10-10 DOI: 10.17509/ijost.v7i3.51325
A. Fristiohady, Rathapon Asasutjarit, L. Purnama, Sewan Theeramunkong, Wirhamsah Al-Ramadan, Lidya Agriningsih Haruna, Nurisma Rahmatika, S. Baharum, I. Sahidin
Melanoma skin cancer is a malignant melanocyte tumor considered the most invasive and dangerous skin cancer, with an average five-year survival rate of less than 5% after metastasis. Thus, a new strategy for preventing and treating cancer from the natural product is required. Medicinal plants are the potential as an alternative against cancer. This review article aims to determine natural products from medicinal plants which have the potential as an anticancer in melanoma skin cancer in vitro and in vivo. 40 plants have been selected based on the selection criteria for anticancer compounds. In vitro studies showed that the plant can reduce cell viability through cell cycle inhibition and apoptosis induction and inhibit angiogenesis, invasion, and metastasis in human melanoma skin cancer. Therefore, further research is required to explore more plants, especially medicinal plants, their active compounds, and the mechanism of anticancer action to be used as standard herbal medicines.
黑色素瘤皮肤癌是一种恶性黑色素细胞肿瘤,被认为是最具侵袭性和危险性的皮肤癌,转移后平均5年生存率不到5%。因此,需要一种从天然产物中预防和治疗癌症的新策略。药用植物是抗癌的潜在替代品。本文旨在从药用植物中寻找具有体外和体内抗黑色素瘤皮肤癌潜力的天然产物。根据抗癌化合物的选择标准,选择了40种植物。体外研究表明,该植物可以通过抑制细胞周期和诱导细胞凋亡来降低人黑色素瘤皮肤癌的细胞活力,抑制血管生成、侵袭和转移。因此,需要进一步的研究来探索更多的植物,特别是药用植物,它们的活性化合物和抗癌作用的机制,以作为标准的中草药。
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引用次数: 1
Strawberry-fortified Yogurt: Production, Sensory, Antioxidant Activity Test, and Model for Practicum 草莓强化酸奶:生产、感官、抗氧化活性测试和实习模型
Q1 Earth and Planetary Sciences Pub Date : 2022-10-10 DOI: 10.17509/ijost.v7i3.51520
F. Supriyanti, Dida Roslina, Z. Zackiyah, Islah Hanifa
This study aims to produce as well as analyze the sensory and antioxidant activity of fortified strawberry yogurt with cryoconcentration and pasteurization preparation methods. The results for the sensory test of strawberry fortified yogurt showed that the pasteurized yogurt is the best for taste and aroma because the use of heat when pasteurizing releases the aroma from strawberries. Reducing the water content using this method allows the strawberry flavor more concentrated. The cryoconcentration method allows the texture and color to be better than other methods. This is influenced by the use of low temperatures in the cryoconcentration method to maintain the anthocyanin content in strawberries which acts as a red pigment. The greater concentration of fortificants added results in higher antioxidant activity gained. Based on the IC100 value, the fortification of strawberries with the cryoconcentration method was significantly different from the pasteurization method in increasing the antioxidant activity of strawberry-fortified yogurt. The benefit of this research is to process milk into yogurt. Thus, it can be consumed by consumers with lactose intolerant sufferers. The addition of strawberries increases the antioxidants to prevent degenerative diseases. In addition, due to its simply design and production, this study is possibly used as a model in the practicum class.
本研究旨在通过低温浓缩和巴氏灭菌两种制备方法制备强化草莓酸奶,并分析其感官和抗氧化活性。对草莓强化酸奶的感官测试结果表明,巴氏杀菌酸奶的口感和香气最好,因为在巴氏杀菌时加热使草莓的香气释放出来。用这种方法降低草莓的水分含量,可以使草莓的味道更加浓缩。低温浓缩法可以使质地和颜色比其他方法更好。这是由于在低温浓缩法中使用低温来保持草莓中作为红色色素的花青素含量。添加的强化剂浓度越高,获得的抗氧化活性越高。根据IC100值,低温浓缩法强化草莓在提高草莓强化酸奶抗氧化活性方面与巴氏灭菌法有显著差异。这项研究的好处是将牛奶加工成酸奶。因此,乳糖不耐症患者可以食用它。草莓的加入增加了抗氧化剂,以防止退化性疾病。此外,由于设计制作简单,本研究可以作为实习课的样板。
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引用次数: 0
Research Mapping in the Use of Technology for Fake News Detection: Bibliometric Analysis from 2011 to 2021 假新闻检测技术应用的研究图谱:2011 - 2021年的文献计量分析
Q1 Earth and Planetary Sciences Pub Date : 2022-10-10 DOI: 10.17509/ijost.v7i3.51449
B. Gunawan, Barito Mulyo Ratmono, Ade Gafar Abdullah, Nada Sadida, Hendra Kaprisma
This study aims to (1) determine research developments, (2) produce research distribution maps based on co-authorship analysis, (3) produce research distribution maps based on citation analysis, (4) produce research distribution maps based on co-citation analysis, (5) produce a research distribution map based on co-occurrence analysis, and (6) find out the state-of-the-art research in the use of technology for fake news detection. This study uses a quantitative method with a descriptive approach in bibliometric analysis from 2011 to 2021. From the research results obtained (1) the development of research publications in the field of the use of technology for fake news detection shows an increase, (2) the interrelationships between countries of authors, organizations affiliated with the authors, and among authors, (3) distribution map of citation analysis based on units of countries, sources, and authors, (4) distribution map of co-citation analysis based on unit cited sources and cited authors, (5) connection of keyword in the use of technology for fake news detection publications is related to literacy skills such as media literacy and information literacy, and (6) several research trends that researchers have widely used in the last 2 years including COVID-19, media literacy, and cyber deception. The research results can be used to determine the development of research o in the use of technology for fake news detection and as a reference for developing further research in the use of technology for fake news detection.
本研究旨在(1)确定研究进展,(2)基于合著分析绘制研究分布图,(3)基于引文分析绘制研究分布图,(4)基于共被引分析绘制研究分布图,(5)基于共现分析绘制研究分布图,以及(6)找出利用技术检测假新闻的最新研究进展。本研究采用定量方法结合描述性方法对2011 - 2021年的文献计量学进行分析。从研究结果来看:(1)利用技术检测假新闻领域的研究出版物的发展呈现增长趋势;(2)作者所在国家、作者所属组织和作者之间的相互关系;(3)基于国家、来源和作者单位的引文分析分布图;(4)基于单位被引来源和被引作者的共被引分析分布图;(5)假新闻检测出版物使用技术时关键字的连接与媒介素养和信息素养等素养技能有关;(6)过去两年研究人员广泛使用的几种研究趋势,包括COVID-19、媒介素养和网络欺骗。研究结果可以用来确定假新闻检测技术使用研究的发展方向,并为进一步开展假新闻检测技术使用研究提供参考。
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引用次数: 2
A Systematic Review of the IoT in Smart University: Model and Contribution 智慧大学物联网系统综述:模式与贡献
Q1 Earth and Planetary Sciences Pub Date : 2022-10-10 DOI: 10.17509/ijost.v7i3.51476
S. Luckyardi, R. Hurriyati, D. Disman, P. Dirgantari
The objectives of the review were to identify different implementation aspects of the Internet of Things (IoT) in Smart Universities (SU) from diverse studies, amplify the theories behind the IoT utilization and model in SU; as well as offer recommendations for future research in this area. This study employed a systematic literature review (SLR) technique, conducting comprehensive searches of the most relevant articles to the research question published from 2018 to 2022. Following a review of peer-reviewed journals, a total of 69 refereed articles were chosen and analyzed. The findings of this study suggest that the technology model needs to be aligned and integrated with organizational processes. IoT utilization should meet the adoption readiness of a university. The results also revealed that the creation of SU can be divided into three categories: behavior, learning, educational technology, and physical facilities. However, the literature related to IoT utilization and model is still incoherent and lacking in theoretical frameworks that reflect on specific circumstances such as SU. SU research is still in its early stages, with more work to be done in terms of identifying technology model adoption. The review also contributed to serving as inspiration and a point of reference for institutions as they work with the smart university initiative to create a teaching and learning environment that is more effective and efficient.
回顾的目的是从不同的研究中确定物联网(IoT)在智能大学(SU)中的不同实施方面,扩大物联网在SU中的应用和模型背后的理论;并对该领域未来的研究提出建议。本研究采用系统文献综述(SLR)技术,对2018年至2022年发表的与研究问题最相关的文章进行全面检索。在对同行评议的期刊进行审查之后,总共选择并分析了69篇被评审的文章。本研究的结果表明,技术模型需要与组织过程保持一致和集成。物联网的利用应满足大学的采用准备。结果还显示,SU的创建可以分为三个类别:行为,学习,教育技术和物理设施。然而,与物联网利用和模型相关的文献仍然不连贯,缺乏反映SU等具体情况的理论框架。SU研究仍处于早期阶段,在识别技术模型采用方面需要做更多的工作。检讨亦为各院校提供启发和参考,协助它们配合“智慧大学”计划,创造更有效的教与学环境。
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引用次数: 2
A systematic Literature Review of Internet of Things for Higher Education: Architecture and Implementation 高等教育物联网系统文献综述:架构与实现
Q1 Earth and Planetary Sciences Pub Date : 2022-10-10 DOI: 10.17509/ijost.v7i3.51464
E. S. Soegoto, H. Soegoto, D. Soegoto, Suryatno Wiganepdo Soegoto, Agis Abhi Rafdhi, Herry Saputra, D. Oktafiani
The objectives of this paper are to analyze the implementation and architecture of the Internet of Things (IoT) from previous studies, specifically in the world of higher education; offer recommendations for future research, as well as strengthen the theory of IoT architecture that already exists in higher education. This study employed a systematic literature review (SLR) with data collection utilizing Funnel Diagrams to select articles based on their relevance to the research question. The three publisher databases (Scopus, Emerald, and EBSCO) and index journals were utilized in the search for articles. A total of 1,200 articles were gathered from these three sources, with distributions of up to 800 in Scopus, 150 in Emerald, and 250 in EBSCO. The findings demonstrate that the existing IoT architecture has a more sophisticated model than the fundamental idea, which has three layers, implying that using IoT in education may have a significant influence on user convenience. This is due to the increasingly complicated requirements of higher education's many business procedures. This study serves as an inspiration and reference for future research for higher education institutions that include the Internet of Things in their implementation to build an efficient teaching and learning environment.
本文的目的是从以前的研究中分析物联网(IoT)的实施和架构,特别是在高等教育领域;为未来的研究提供建议,并加强高等教育中已经存在的物联网架构理论。本研究采用系统文献综述(SLR),利用漏斗图收集数据,根据与研究问题的相关性选择文章。三个出版商数据库(Scopus, Emerald和EBSCO)和索引期刊被用来搜索文章。从这三个来源共收集了1200篇文章,其中Scopus中有800篇,Emerald中有150篇,EBSCO中有250篇。研究结果表明,现有的物联网架构具有比基本理念更复杂的模型,基本理念有三层,这意味着在教育中使用物联网可能对用户便利性产生重大影响。这是由于高等教育的许多业务流程要求越来越复杂。本研究对未来高等院校在实施物联网的过程中,构建高效的教与学环境具有一定的启发和借鉴意义。
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引用次数: 2
Simultaneous Decolorization of Tartrazine and Production of H2 in a Combined Electrocoagulation and Photocatalytic Processes using CuO-TiO2 Nanotube Arrays: Literature Review and Experiment CuO-TiO2纳米管阵列电混凝光催化同时脱色酒黄石和制氢:文献综述和实验
Q1 Earth and Planetary Sciences Pub Date : 2022-10-10 DOI: 10.17509/ijost.v7i3.51315
S. Slamet, Laily F. Pelawi, M. Ibadurrohman, R. Yudianti, R. Ratnawati
We reported the simultaneous decolorization of tartrazine and H2 production via electrocoagulation and photocatalysis using CuO-doped TiO2 nanotube arrays (TNTA) composites. Tartrazine was removed by the combination of adsorption, electrocoagulation, and photocatalytic degradation, while H2 was produced through water reduction at the cathode and water splitting process on the photocatalyst surface. The photoreactor contains CuO-TNTA as a photocatalyst and is equipped with an 80-W UV lamp. Deposition of CuO on TNTA was conducted using a successive ionic layer adsorption and reaction (SILAR) method. The nanotubular of the TNTA as well as the distribution of CuO were evaluated employing FESEM and HRTEM. XRD patterns confirmed weak diffraction of CuO and TNTA revealing an anatase crystallite phase. The band gap of the CuO-TNTA was also found to be redshifted from that of pure TNTA. The simultaneous processes with the combined systems (20 V, pH = 11) managed to remove 80% of tartrazine while producing a high H2 yield (1.84 mmol), significantly higher than those obtained by each process.
我们报道了利用掺杂cuo的TiO2纳米管阵列(TNTA)复合材料通过电凝和光催化同时脱色酒黄和产氢。通过吸附、电絮凝、光催化降解联合去除酒黄,通过阴极水还原、光催化剂表面水裂解制备H2。该光反应器以CuO-TNTA为光催化剂,并配有80 w紫外灯。采用连续离子层吸附反应(SILAR)法在TNTA上沉积CuO。利用FESEM和HRTEM对TNTA的纳米管结构和CuO的分布进行了表征。XRD谱图证实了CuO和TNTA的弱衍射,显示出锐钛矿晶相。与纯TNTA相比,CuO-TNTA的带隙也发生了红移。组合体系(20 V, pH = 11)同时处理时,酒石黄的去除率为80%,H2产率为1.84 mmol,显著高于单独处理的H2产率。
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引用次数: 1
Heavy Oil Potentials in Central Sumatra Basin, Indonesia Using Remote Sensing, Gravity, and Petrophysics Data: From Literature Review to Interpretations and Analyses 利用遥感、重力和岩石物理数据研究印度尼西亚苏门答腊盆地中部稠油潜力:从文献综述到解释和分析
Q1 Earth and Planetary Sciences Pub Date : 2022-10-10 DOI: 10.17509/ijost.v7i3.51288
T. M. Susantoro, S. Suliantara, H. Setiawan, B. Widarsono, K. Wikantika
Central Sumatra basin is located on Sumatra Island, Indonesia, and is considered an oil prolific basin that produces heavy oil. The basin is believed to have unexplored heavy oil potential. Therefore, this study aims to map the heavy oil potential distribution in the basin using surface and subsurface lineaments analyses interpreted from satellite imagery and gravity data, and assisted by well log/petrophysics analysis. A thorough basin analysis was conducted based on surface/subsurface structures’ control and source rock location settings to map all potential heavy oil traps. The gravity anomaly data interpretation identified the low areas and lineaments in NW – SE, and N – S directions. The interpretation of satellite imageries showed very similar lineament patterns with the same general direction. It was observed that there is continuity between subsurface and surface lineament features, which provide contact between reservoirs and surface water sources, thereby facilitating heavy oil generation. Overlapping the lineament interpretation of gravity and satellite imagery data, supported by petroleum system understanding and verification from wells data have confirmed 7 heavy oil trap potential areas within the sedimentary basin.
中苏门答腊盆地位于印度尼西亚苏门答腊岛,被认为是一个盛产重油的盆地。该盆地被认为有未开发的重油潜力。因此,本研究旨在利用卫星图像和重力数据解释的地表和地下轮廓分析,并辅以测井/岩石物理分析,绘制盆地稠油潜力分布图。基于地表/地下构造控制和烃源岩位置设置,进行了全面的盆地分析,以绘制所有潜在的稠油圈闭。重力异常资料解释确定了NW - SE和N - S方向的低区和低线。对卫星图像的解释显示出大致方向相同的非常相似的轮廓图案。研究发现,地下和地表线状特征之间存在连续性,为储层和地表水水源之间提供了联系,从而有利于稠油的生成。在对含油气系统的认识和井资料的验证的支持下,叠加重力和卫星图像数据的线性解释,确定了沉积盆地内7个稠油圈闭潜在区域。
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引用次数: 1
Management Information Systems: Bibliometric Analysis and Its Effect on Decision Making 管理信息系统:文献计量分析及其对决策的影响
Q1 Earth and Planetary Sciences Pub Date : 2022-10-10 DOI: 10.17509/ijost.v7i3.56368
Budi Santoso, T. Hikmawan, Nani Imaniyati
Decision-making in the organization always relates to the description of the results of the decisions taken. Therefore, every organization needs a management information system to assist in making various kinds of decisions needed. The purpose of this study was to determine the influence and effectiveness of management information systems on decision-making in the field of archives. The method used in this study is the explanatory survey method. Data collection techniques were carried out using questionnaires and product correlation moments. Data analysis was performed using simple regression analysis and hypothesis testing. The subjects of this study were 120 administrative employees in the city of Bandung. To support the analysis, this study also carried out a bibliometric analysis to determine trends in research development from information management systems to decision-making. Based on the findings, the quality of the management information system used is in the high category, as well as the effectiveness of decision-making is in the high category. Based on the results of hypothesis testing and significance, it can be interpreted that the management information system has a positive and significant effect on decision-making in the field of administration.
组织中的决策总是与所做决策的结果的描述有关。因此,每个组织都需要一个管理信息系统来协助做出各种所需的决策。这项研究的目的是确定管理信息系统对档案领域决策的影响和有效性。本研究采用的方法是解释性调查法。采用问卷调查法和产品相关矩法进行数据收集。数据分析采用简单回归分析和假设检验。本研究以万隆市120名行政人员为研究对象。为了支持分析,本研究还进行了文献计量分析,以确定从信息管理系统到决策的研究发展趋势。根据调查结果,所使用的管理信息系统的质量属于高类别,决策的有效性属于高类别。根据假设检验和显著性的结果,可以解释为管理信息系统对行政领域的决策具有积极而显著的影响。
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引用次数: 3
Dye-Doped Fe3O4 Nanoparticles for Magnetically Controlling Random Laser Parameters at Visible Wavelengths: Literature Review and Experiment 用于磁控可见波长随机激光参数的染料掺杂Fe3O4纳米颗粒:文献综述和实验
Q1 Earth and Planetary Sciences Pub Date : 2022-10-10 DOI: 10.17509/ijost.v7i3.51453
M. Al-Samak, J. M. Jassim
The development of light-controlled electronic devices requires new possibilities of optical control via tuning of laser input parameters. Here, Fe3O4 superparamagnetic nanoparticles (SNPs) were doped with dye, and the controllability of parameters of a random laser, including the wavelength, threshold energy, and intensity under the absence and presence of an external magnetic field was studied. The prepared dye laser (Rh-640) showed strong magnetic controllability and switch ability under different pumping energies (1‒7 mJ), as well as good responsivity and durability at visible wavelengths. The applied magnetic field was utilized to modify the distribution of Fe3O4 SNPs with different concentrations and scattering behavior, altering the generation of coherent loops and laser action properties. Thus, it was possible to employ the magnetically controllable random laser in a variety of technological applications, including biology and optical communications
光控电子器件的发展需要通过调整激光输入参数来实现光控的新可能性。本文采用染料掺杂Fe3O4超顺磁性纳米粒子(SNPs),研究了在外加磁场存在和不存在的情况下,随机激光器的波长、阈值能量和强度等参数的可控性。制备的染料激光器(Rh-640)在不同泵浦能量(1 ~ 7 mJ)下具有较强的磁可控性和开关能力,在可见光波段具有良好的响应性和耐久性。利用外加磁场改变不同浓度Fe3O4 snp的分布和散射行为,改变其产生的相干环和激光作用特性。因此,可以将磁可控随机激光器应用于各种技术应用,包括生物学和光通信
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引用次数: 1
Experimental Study on The Characterization of Pyrolysis Products from Bagasse (Saccharum Officinarum L.): Bio-oil, Biochar, and Gas Products 甘蔗渣(Saccharum Officinarum L.)热解产物表征的实验研究:生物油、生物炭和气体产物
Q1 Earth and Planetary Sciences Pub Date : 2022-10-10 DOI: 10.17509/ijost.v7i3.51566
S. Jamilatun, J. Pitoyo, Shinta Amelia, A. Ma’arif, D. C. Hakika, I. Mufandi
Sugarcane bagasse is one of the most abundant biomasses. This study aims to examine the characteristics of bagasse using a pyrolysis system to produce liquid, solid (Biochar), and gaseous. A fixed bed reactor was installed in pyrolysis with temperature variations from 300 to 600°C. The ultimate and proximate analysis was applied to evaluate the characteristic of bagasse. The experimental result found that the maximum bio-oil was obtained at a temperature of 550°C. Several characterizations were done, including gas chromatography and surface area analysis. The Levoglucosan compound of 78% area. The temperature effect on pyrolysis influenced the O/C ratio, H/C ratio, HHV value, and surface area of biochar. The High Heating Value was obtained from 16.698 to 18.496 kJ/kg. Biochar results indicated that the surface area, average pore size, and total pore volume are 180.3-198.0 m2/g, 1.42-4.33 nm, and 0.11-0.12 nm, respectively. The study also analyzed its composition in biochar.
甘蔗渣是最丰富的生物质之一。本研究旨在研究利用热解系统生产液体、固体(生物炭)和气体的甘蔗渣的特性。采用固定床反应器进行热解,热解温度为300 ~ 600℃。应用极值分析和近似分析对甘蔗渣的特性进行了评价。实验结果表明,在温度为550℃时,生物油的含量最高。进行了几种表征,包括气相色谱和表面积分析。左旋葡聚糖化合物面积78%。温度对热解的影响影响了生物炭的O/C比、H/C比、HHV值和表面积。高热值为16.698 ~ 18.496 kJ/kg。生物炭实验结果表明,活性炭的比表面积为180.3 ~ 198.0 m2/g,平均孔径为1.42 ~ 4.33 nm,总孔容为0.11 ~ 0.12 nm。该研究还分析了其在生物炭中的成分。
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引用次数: 2
期刊
Indonesian Journal of Science and Technology
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