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Internuclear Ophthalmoplegia Following COVID-19 with Abnormal Findings on Neuroimaging; A Case Report. COVID-19 后出现核内眼球震颤,神经影像学检查结果异常;病例报告。
Q3 Medicine Pub Date : 2024-07-01 Epub Date: 2024-08-14 DOI: 10.1080/2576117X.2024.2386198
Farahnaz Abdolhoseinzade, Arash Mirmohammadsadeghi, Shervin Sharifkashani, Mohammad Reza Akbari, Babak Masoomian, Motahhareh Sadeghi

COVID-19 had been reported to be associated with neuro-ophthalmic complications. However, there is a shortage of evidence regarding internuclear ophthalmoplegia (INO) presentation after COVID-19 infection with related brain magnetic resonance imaging (MRI). Herein, we report a case of INO in a 69-year-old woman with presentation of diplopia following COVID-19 infection, along with her neuroimaging. We concluded that it is important to recognize the possibility of INO in patients with diplopia after COVID-19 and to consider brain MRI as an informative tool in these patients.

据报道,COVID-19与神经眼科并发症有关。然而,有关 COVID-19 感染后出现核内眼球震颤(INO)以及相关脑磁共振成像(MRI)的证据却很缺乏。在此,我们报告了一例感染 COVID-19 后出现复视的 69 岁女性 INO 病例及其神经影像学表现。我们的结论是,在 COVID-19 感染后出现复视的患者中,认识到 INO 的可能性并将脑磁共振成像作为这些患者的信息工具非常重要。
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引用次数: 0
How does the Surgical Repair of Ptosis Impact Refractive Error? 上睑下垂手术修复对屈光不正有何影响?
Q3 Medicine Pub Date : 2024-07-01 Epub Date: 2024-08-14 DOI: 10.1080/2576117X.2024.2384685
Kaajal D Nanda, Katherine Sanchez, Jenny Yu

Purpose: To identify a correlation between the degree of congenital ptosis and levels of refractive error, visual stimulus deprivation and anisometropic amblyopia, and any improvement with surgical intervention.

Methods: A prospective investigation of 30 patients aged 3 months to 8 years, with a diagnosis of unilateral or bilateral congenital ptosis. A full orthoptic assessment and cycloplegic refraction were performed and patients requiring surgical intervention for ptosis were at surgeon discretion.

Results: The mean age at presentation was 27.1 months. The prevalence of amblyopia ranged from 19 to 29%. There was no significant difference in the levels of astigmatism throughout the follow-up period between patients who underwent surgical intervention and who did not. There was a significant improvement in the visual acuity of the affected eye (p = .03) and both eyes open (p = .02), in patients who did not undergo surgery. This was then repeated on patients who underwent surgical intervention which showed no significant difference in the affected eye or both eyes open; p = .27, p = .32, respectively.

Conclusion: There is no significant change in the levels of astigmatism in both patients who underwent surgery and those who did not. Conservative management of congenital ptosis, while counterintuitive, proves not to deleteriously affect the visual potential of these patients.

目的:确定先天性上睑下垂的程度与屈光不正、视觉刺激剥夺和异向性弱视的程度之间的相关性,以及手术干预后的改善情况:对 30 名年龄在 3 个月至 8 岁之间、被诊断为单侧或双侧先天性上睑下垂的患者进行前瞻性调查。对患者进行了全面的正视评估和屈光检查,需要手术治疗上睑下垂的患者由外科医生决定:平均发病年龄为 27.1 个月。弱视发生率为 19%至 29%。在整个随访期间,接受手术治疗和未接受手术治疗的患者在散光程度上没有明显差异。未接受手术的患者患眼视力(p = 0.03)和双眼睁开视力(p = 0.02)均有明显改善。然后,对接受手术治疗的患者进行复查,结果显示患眼和睁开双眼的视力无明显差异;分别为 p = .27 和 p = .32:结论:接受手术治疗和未接受手术治疗的患者的散光程度均无明显变化。先天性上睑下垂的保守治疗虽然与直觉相反,但证明不会对这些患者的视觉潜能产生有害影响。
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引用次数: 0
The Challenge of Strabismus Surgery for Patients with Hemianopic Visual Field Defects Associated with Ocular Deviations. 眼球偏斜导致半球形视野缺损患者斜视手术的挑战。
Q3 Medicine Pub Date : 2024-07-01 Epub Date: 2024-08-19 DOI: 10.1080/2576117X.2024.2386204
Pilar Merino, Lucas Gómez, Pilar Gómez de Liaño, Jacobo Yáñez-Merino

Homonymous and heteronymous hemianopias associated with strabismus are a therapeutic challenge because surgery may result in diplopia, decrease the visual field (VF), and/or lead to recurrence of the deviation. We present four cases: two homonymous hemianopias and two heteronymous hemianopias. Of the four patients, three had exotropia and one had esotropia. The origin of hemianopias was neoplastic in two cases and traumatic in two cases. Strabismus surgery was performed in three cases, but only one case had a good result; recurrence of the deviation and diplopia occurred in the other two cases. In conclusion, exotropia may develop as a compensatory mechanism in a patient with congenital or early-onset homonymous hemianopia and realigning the eyes could reduce the binocular VF and cause diplopia. In heteronymous hemianopias, there is little risk of the surgery causing diplopia, but the strabismus is unstable because of the absence of binocular vision and vergence reflexes if VF loss includes the macula. Further, strabismus, in association with hemianopia, may be caused by coexistent cranial nerve and/or gaze palsy. The prognosis, objective, and results of the strabismus operation should be clearly discussed with the patients or their guardians before it is performed if hemianopias are present.

与斜视相关的同名和异名半身不遂是一项治疗难题,因为手术可能导致复视、视野缩小和/或导致偏斜复发。我们介绍了四例病例:两例同名半身不遂,两例异名半身不遂。四名患者中,三名患有外斜视,一名患有内斜视。两例半身不遂的病因是肿瘤,两例是外伤。三例患者接受了斜视手术,但只有一例效果良好;另外两例患者的偏斜和复视复发。总之,外斜可能是先天性或早发性同向半身不遂患者的一种代偿机制,调整双眼的位置可能会降低双眼VF并导致复视。在异名半身不遂患者中,手术导致复视的风险很小,但斜视是不稳定的,因为如果 VF 缺失包括黄斑,患者就会失去双眼视力和辐辏反射。此外,斜视与半身不遂可能是由并存的颅神经和/或凝视麻痹引起的。如果存在偏盲,在手术前应与患者或其监护人明确讨论斜视手术的预后、目的和结果。
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引用次数: 0
Uncertainties Regarding the Lifetime Reoperation Rate After Strabismus Surgery. 斜视手术后终生再手术率的不确定性。
Q3 Medicine Pub Date : 2024-07-01 Epub Date: 2024-08-14 DOI: 10.1080/2576117X.2024.2385507
Christopher Theodore Leffler, Evan Silverstein, Carolyn May
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引用次数: 0
Lateral Rectus Disabling and Simultaneous Modified Nishida Procedure for Exotropic Duane Retraction Syndrome. 外向性杜安回缩综合征的外侧直肌禁用术和同时进行的改良西田手术。
Q3 Medicine Pub Date : 2024-07-01 Epub Date: 2024-07-22 DOI: 10.1080/2576117X.2024.2375666
Karthikeyan Arcot Sadagopan, Nithya Raghunandan, Neha Satish Saswade, Burton J Kushner

Exotropic-Duane Syndrome (XT-DRS) is a congenital cranial nerve dysinnervation disorder characterized by exotropia, anomalous head posture (contralateral face turn), limited adduction, globe retraction, palpebral fissure narrowing, upshoot and downshoot in adduction, and varying levels of limitation of abduction. Patients with XT-DRS often have poor convergence because attempted convergence induces co-contraction of the lateral rectus muscle (LR) due to anomalous LR innervation. We describe two patients with XT-DRS who underwent simultaneous lateral rectus muscle (LR) disinsertion and periosteal fixation (LRDAPF) and modified Nishida procedure (MNP) and discuss their outcome. In one patient, we combined this procedure with a contralateral LR recession. Anomalous head posture, exotropia, globe retraction, and palpebral fissure narrowing were reduced. Upshoot and downshoot were also reduced. Convergence improved in both patients.

外展-杜安综合征(XT-DRS)是一种先天性颅神经支配障碍性疾病,其特征为外斜、头部姿势异常(对侧脸部转向)、内收受限、眼球后缩、睑裂变窄、内收上移和下移以及不同程度的外展受限。XT-DRS患者的辐辏功能通常很差,因为辐辏功能异常会导致外侧直肌(LR)的共同收缩。我们描述了两名同时接受了外侧直肌(LR)剥离和骨膜固定术(LRDAPF)和改良西田手术(MNP)的 XT-DRS 患者,并讨论了他们的治疗结果。在一名患者中,我们将该手术与对侧 LR 后缩手术相结合。患者的异常头姿、外斜视、眼球后缩和睑裂狭窄均有所减轻。上视和下视也有所减少。两名患者的辐辏均有所改善。
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引用次数: 0
Intermittent Exotropia: The Effect of Alternating Occlusion Therapy on Control of Strabismus. 间歇性外斜:交替闭塞疗法对斜视控制的影响
Q3 Medicine Pub Date : 2024-04-01 Epub Date: 2024-04-22 DOI: 10.1080/2576117X.2024.2340213
Martin Boersma

Background: Intermittent exotropia is a common form of pediatric strabismus characterized by intermittent misalignment of the eyes. This study investigated the clinical effectiveness of alternating occlusion therapy as a non-surgical alternative for children aged 3-10 with intermittent exotropia.

Methods: A comprehensive review of recent research, including randomized controlled trials and case series, was conducted. These studies utilized standardized control scores to assess the impact of alternating occlusion therapy on both distance and near control of alignment.

Results: The findings indicated a significant improvement in exotropia control, particularly at distance fixation, among children undergoing alternating occlusion therapy. While some variability in outcomes exists, all articles demonstrate positive responses to this noninvasive approach. Notably, the patients with poor initial control tended to benefit the most.

Discussion: The potential advantages of alternating occlusion therapy are its cost-effectiveness and noninvasive nature. However, it is essential to manage patient and parental expectations and address potential drawbacks, including social stress, irritation associated with occlusion therapy and the possibility that strabismus surgery may still be needed in the future because of decompensation.

Conclusion: Alternating occlusion therapy is a promising option to improve exotropia control in children with intermittent exotropia. It offers a viable non-surgical strategy to delay or potentially avoid strabismus surgery, although approximately 45% of the patients might eventually still require strabismus surgery. Healthcare providers should carefully weigh the benefits and limitations of this intervention to make informed decisions through shared decision-making with the patients and their families. This review offers diverse insights into the clinical management of intermittent exotropia and provides an evidence-based alternative to surgical interventions.

背景:间歇性外斜是一种常见的小儿斜视,其特点是双眼间歇性错位。本研究调查了交替闭锁疗法作为一种非手术替代疗法对 3-10 岁间歇性外斜视儿童的临床疗效:方法:对近期的研究进行了全面回顾,包括随机对照试验和系列病例。这些研究利用标准化控制评分来评估交替闭塞疗法对远近对齐控制的影响:结果:研究结果表明,接受交替咬合疗法的儿童在外斜视控制方面有明显改善,尤其是在远距离固定方面。虽然结果存在一些差异,但所有文章都显示了这种非侵入性方法的积极效果。值得注意的是,最初控制不佳的患者往往受益最多:讨论:交替闭塞疗法的潜在优势在于其成本效益和非侵入性。讨论:交替闭塞疗法的潜在优势在于其成本效益和非侵入性,但必须管理好患者和家长的期望,并解决潜在的弊端,包括社会压力、与闭塞疗法相关的刺激,以及将来可能由于失代偿而仍需进行斜视手术:结论:交替闭塞疗法是改善间歇性外斜儿童外斜控制的一种可行方法。尽管约有 45% 的患者最终仍可能需要接受斜视手术,但交替闭锁疗法为延迟或可能避免斜视手术提供了一种可行的非手术策略。医疗服务提供者应仔细权衡这一干预措施的益处和局限性,通过与患者及其家属共同决策,做出明智的决定。本综述为间歇性外斜的临床治疗提供了不同的见解,并为手术干预提供了循证替代方案。
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引用次数: 0
Inferior Rectus Muscle Y-Split for Thyroid-Related Vertical Strabismus. 下直肌Y形切开术治疗甲状腺相关性垂直斜视
Q3 Medicine Pub Date : 2024-04-01 Epub Date: 2024-04-16 DOI: 10.1080/2576117X.2024.2334968
Yoon H Lee, Stacy L Pineles, Pimpiroon Ploysangam, Federico G Velez

Incomitant hypotropia in thyroid eye disease can be difficult to manage, especially in the presence of orthotropia with fusion in down gaze and reading position. Recessing the affected ipsilateral inferior rectus muscle may result in an undesirable downgaze diplopia secondary to a hypertropia in downgaze. Various surgical techniques have been described to manage this potential complication including asymmetric recession of both inferior rectus muscles, posterior myoscleropexy operation, and the Scott recess/resect procedure of the contralateral inferior rectus. In 2004, Hoerantner et al. introduced the y-split recession of the medial rectus muscle for near esotropic deviations. The anterior portion of muscle is split and secured in a y-shaped configuration, which reduces the muscle lever arm and helps minimize incomitance and muscle slippage. Unlike the traditional Cüppers Faden, a y-split recession results in torque reduction in all gaze positions. In addition, a y-split recession does not involve scleral passes posteriorly reducing the risk of globe perforation. We report a patient with incomitant strabismus secondary to thyroid eye disease who underwent a combination of traditional recession and y-splitting recession of the contralateral inferior rectus muscle, resulting in good functional alignment in primary gaze and in the reading position.

甲状腺眼病并发的斜视可能很难处理,尤其是在下视和阅读姿势融合的情况下。回缩受影响的同侧下直肌可能会因为下视时眼球过度倾斜而导致不理想的下视复视。为处理这种潜在的并发症,已有多种手术方法,包括两侧下直肌的不对称后缩、后方肌硬化手术以及对侧下直肌的 Scott 后缩/切除术。2004 年,Hoerantner 等人提出了内侧直肌 Y 形分割后退术,用于治疗近内侧偏斜。肌肉的前部被分割并固定成 Y 形结构,从而减少了肌肉杠杆臂,有助于最大限度地减少入位和肌肉滑动。与传统的 Cüppers Faden 不同,Y 形分割后缩可减少所有注视位置的扭矩。此外,Y形分割后缩不涉及后方的巩膜通道,降低了眼球穿孔的风险。我们报告了一位继发于甲状腺眼病的不伴有斜视的患者,她接受了传统后缩和对侧下直肌Y形分割后缩联合手术,结果在主要注视和阅读姿势下都获得了良好的功能对位。
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引用次数: 0
Risks and Complications Discussed in Consent for Strabismus Surgery. 斜视手术同意书中讨论的风险和并发症。
Q3 Medicine Pub Date : 2024-04-01 Epub Date: 2024-05-28 DOI: 10.1080/2576117X.2024.2352176
Carolyn May, Evan Silverstein

This study is a qualitative analysis of the consent process for strabismus surgery, using recordings of physicians doing a mock consent for bilateral medial rectus recession. There is considerable variation in the risks of surgery and odds of complications that are cited by pediatric ophthalmologists during the consent process. We propose a reference table with complication rates for use during the consent process.

本研究是对斜视手术同意过程的定性分析,使用的是医生对双侧内侧直肌后退术进行模拟同意的录音。小儿眼科医生在同意过程中提到的手术风险和并发症几率存在很大差异。我们建议在同意过程中使用并发症发生率参考表。
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引用次数: 0
Diagnostic Protocol for Accommodative and Vergence Anomalies - A Review. 适应性和远视异常的诊断方案 - 综述。
Q3 Medicine Pub Date : 2024-04-01 Epub Date: 2024-06-20 DOI: 10.1080/2576117X.2024.2347663
Mousumi Saikia, Kamal Pant, Joydeep Dutta

Purpose: To review the diagnostic protocols of non-strabismic binocular vision anomalies.

Methods: We carried out a literature search on published articles of non-strabismic accommodative and vergence anomalies in different international optometry and ophthalmology journals found in the Pubmed, ResearchGate, Google Scholar, and MEDLINE databases.

Results: The diagnostic criteria and normative data from the nine articles selected show discrepancies and variability in methodologies and techniques in the overall assessment of Non-Strabismic Binocular Vision Anomalies (NSBVA). Near point of convergence measurement is the most common assessment, whereas the vergence facility is the least commonly used assessment in terms of evaluating convergence insufficiency. Near point of convergence > 10 cm alone is the most sensitive sign to detect convergence insufficiency in a community set-up but high positive relative accommodation (>3.50D) is the most sensitive sign to diagnose accommodative excess. On the other hand, monocular accommodative facility < 7 CPM has the highest sensitivity to confirm the diagnosis of accommodative infacility. This review also indicates that the more clinical signs that are included in a set of diagnostic criteria, the lower the prevalence rate for that diagnosis.

Conclusions: There is no standardized and diagnostically validated protocol for the assessment of NSBVAs. Variable cutoff values obtained using different methods and the selection of diagnostic criteria by various researchers have led to discrepancies that highlight the need for diagnostic validity of available protocols (combination of tests) for each anomaly. Clinical signs such as positive relative accommodation (PRA) for accommodative excess, near point of convergence (NPC) for convergence insufficiency and monocular accommodative facility (MAF) for accommodative infacility were found to be useful diagnostic signs of these anomalies. Studies should be carried out for accommodative and vergence dysfunctions using proper designs and methods to validate diagnostic criteria for all age groups. Standardization of assessment protocol and cutoff criteria will also aid in calculating prevalence for non-strabismic binocular vision anomalies.

目的:研究非斜视性双眼视力异常的诊断方法:我们对Pubmed、ResearchGate、Google Scholar和MEDLINE数据库中不同国际视光学和眼科学期刊上发表的有关非斜视性容纳和辐辏异常的文章进行了文献检索:结果:所选九篇文章的诊断标准和规范数据显示,在对非斜视性双眼视力异常(NSBVA)进行整体评估时,方法和技术存在差异和变异。辐辏近点测量是最常用的评估方法,而辐辏设施是评估辐辏不足最不常用的评估方法。辐辏近点 > 10 厘米是在社区环境中检测辐辏不足最敏感的体征,而高正向相对屈光度(>3.50D)则是诊断屈光过度最敏感的体征。另一方面,单眼适应能力的结论:目前还没有标准化的、经过诊断验证的方案来评估 NSBVA。不同的研究人员使用不同的方法和选择不同的诊断标准得出不同的临界值,这导致了差异,突出了对每种异常的现有方案(测试组合)的诊断有效性的需求。临床体征,如相对容纳阳性(PRA)表示容纳过度,近辐辏点(NPC)表示辐辏不足,单眼容纳能力(MAF)表示容纳不足,被认为是这些异常的有用诊断体征。应采用适当的设计和方法对所有年龄组的适应和辐辏功能障碍进行研究,以验证诊断标准。评估方案和临界标准的标准化也有助于计算非斜视性双眼视力异常的患病率。
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引用次数: 0
Characteristics and Trends of Strabismus Surgeries at a Tertiary Hospital Over 2 Decades - What Can Be Learned for Years to Come? 一家三级医院二十年来斜视手术的特点和趋势--未来几年能学到什么?
Q3 Medicine Pub Date : 2024-04-01 Epub Date: 2024-06-26 DOI: 10.1080/2576117X.2024.2364946
Asaf Israeli, Tom Bar-Asher, Eedy Mezer

Purpose: To analyze characteristics and trends of strabismus surgeries in an Israeli hospital over 2 decades.

Methods: A descriptive, retrospective study including all strabismus surgeries (666) performed during 2000-2019 at an Israeli tertiary hospital. Electronic medical records (EMRs) were directly retrieved to produce an anonymized database.

Results: No trends were evident for age, sex, or ethnicity (p = .294, 0.914 and p = .167, respectively). The mean number of horizontal muscles remained stable, while an increase was noted in the mean number of muscles operated on to repair vertical strabismus (p < .0001). Among acquired cases, a 2.67-fold increase was noted in the proportion of spontaneous strabismus and a decrease of traumatic causes to a third (p < .001). An increase was noted in the proportion of exotropia among horizontal strabismus corrections (p = .022), and esotropia correction techniques distribution changed (p = .004). Reoperations comprised a third of all cases during both decades (p = .198). Reoperations were more prevalent among younger and Jewish patients (p < .001 and p = .024, respectively). Techniques to correct esotropia and exotropia differed significantly between primary surgeries and reoperations (p < .00001 each).

Conclusions: The complexity of surgical techniques increased over time. Ethnic minorities were less prone to reoperations.

目的:分析以色列一家医院二十年来斜视手术的特点和趋势:一项描述性、回顾性研究,包括一家以色列三级医院在 2000-2019 年期间进行的所有斜视手术(666 例)。直接检索电子病历(EMR),生成匿名数据库:年龄、性别或种族无明显趋势(p = .294、0.914 和 p = .167)。水平肌的平均数量保持稳定,而修复垂直斜视的肌肉平均数量有所增加(p p = .022),内斜矫正技术的分布也发生了变化(p = .004)。在这两个十年中,再次手术占所有病例的三分之一(p = .198)。再手术在年轻患者和犹太患者中更为普遍(P = .024)。矫正内斜视和外斜视的技术在初次手术和再次手术中存在显著差异(p 结论:手术技术的复杂性增加了:手术技术的复杂性随着时间的推移而增加。少数族裔较少进行再次手术。
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引用次数: 0
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