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Bilateral Internuclear Ophthalmoplegia Caused by Dengue Fever. 登革热所致双侧核间眼麻痹。
Q3 Medicine Pub Date : 2023-10-02 Epub Date: 2023-07-13
Tanvi Choudhary, Sheetal Malviya, Hansa Thakkar

A 22-year-old male was referred from the medicine department with the chief complaint of double vision for 2 months. The patient had suffered from dengue viral hemorrhagic encephalitis for 2 months for which intensive medical care was given. On ocular examination, both eyes (OU) showed limited adduction with contralateral abducting nystagmus on attempted horizontal gaze. Magnetic resonance imaging of brain showed pontine and midbrain hemorrhages which involved the region of medial longitudinal fasciculus and caused bilateral internuclear ophthalmoplegia (INO). Bilateral INO is very rare and most commonly caused by multiple sclerosis. The presentation of dengue fever causing midbrain and pontine hemorrhages which resulted in bilateral INOs has not been previously reported, to our knowledge.

一名22岁男性被转诊至内科,主要主诉为复视2个月。该患者患有登革热病毒性出血性脑炎2个月,接受了重症监护。在眼部检查中,双眼(OU)在尝试水平凝视时表现出有限的内收和对侧外展性眼球震颤。脑磁共振成像显示脑桥和中脑出血,涉及内侧纵束区域,并导致双侧核间眼肌麻痹(INO)。双侧INO非常罕见,最常见的是由多发性硬化引起。据我们所知,登革热引起中脑和脑桥出血,导致双侧INOs的表现以前没有报道。
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引用次数: 0
What Are Patients Asking Online About Strabismus? An Analysis of the Strabismus Subreddit 患者在网上询问了哪些关于斜视的问题?斜视 Subreddit 分析
Q3 Medicine Pub Date : 2023-10-02 DOI: 10.1080/2576117X.2023.2255082
P. Pakravan, Araliya N Gunawardene, James Lai, J. Sridhar, Kara M. Cavuoto
ABSTRACT Background Reddit is particularly popular due to its anonymity and discussion forum-type format. As an increasing number of patients seek medical advice on social media online, understanding patients’ activity regarding strabismus on Reddit will help assess their concerns and guide patient education. Methods A cross-sectional study of Reddit posts (www.reddit.com/r/strabismus/) was conducted from July 2021 to July 2022. Posts were sorted by date, type, content, emotional tone, and users’ sex and age (when available). Results A total of 709 posts were analyzed. Of the 164 (23%) posts in which users identified sex, 85 (52%) were female. The average age of patients to whom the post regarded was 23.7 ± 11.4 years (range 1–60 years). The most common content was surgical treatment (453, 63.9%), non-surgical treatment (263, 37%), seeking a diagnosis of their condition (190, 26.8%), and sharing personal journeys (136, 19.2%). Of the 289 (41%) posts that conveyed a clear emotional tone, the most common were anxiety (48, 18.3%), happiness (31, 11.8%), insecurity (24, 9.2%), frustration (22, 8.4%), and excitement (22, 8.4%). “Anxiety” posts had a significantly greater association with pre-surgery concerns whereas “happy” posts had a significantly greater association with post-operative updates (p = .003). Conclusions Patients with strabismus who post on Reddit tend to be young adults interested in surgical treatment options. Although the pre-operative tone was anxiety, post-operative posts tended to be happy.
ABSTRACT 背景 Reddit 因其匿名性和论坛形式而特别受欢迎。随着越来越多的患者通过社交媒体在线寻求医疗建议,了解患者在 Reddit 上有关斜视的活动将有助于评估他们的担忧并指导患者教育。方法 在 2021 年 7 月至 2022 年 7 月期间对 Reddit 上的帖子(www.reddit.com/r/strabismus/)进行了横断面研究。帖子按日期、类型、内容、情感基调以及用户的性别和年龄(如有)进行分类。结果 共分析了 709 篇帖子。在 164 篇(23%)用户标明性别的帖子中,85 篇(52%)为女性。帖子涉及的患者平均年龄为 23.7 ± 11.4 岁(1-60 岁不等)。最常见的内容是手术治疗(453,63.9%)、非手术治疗(263,37%)、寻求病情诊断(190,26.8%)和分享个人经历(136,19.2%)。在 289 个(41%)表达明确情绪基调的帖子中,最常见的是焦虑(48 个,18.3%)、快乐(31 个,11.8%)、不安全感(24 个,9.2%)、沮丧(22 个,8.4%)和兴奋(22 个,8.4%)。"焦虑 "帖子与手术前担忧的关联度明显更高,而 "快乐 "帖子与术后更新的关联度明显更高(p = .003)。结论 在 Reddit 上发帖的斜视患者多为对手术治疗方案感兴趣的年轻人。虽然术前的基调是焦虑,但术后的帖子往往是快乐的。
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引用次数: 0
Short Loop Modification of the Semiadjustable Suture Strabismus Procedure for Optional Adjustment. 半可调缝合斜视手术的短环改良。
Q3 Medicine Pub Date : 2023-10-02 Epub Date: 2023-08-25
Klio I Chatzistefanou, Dimitrios Papaconstantinou

Purpose: To present a modification of the semiadjustable suture technique allowing for optional adjustment.

Methods: Short suture loops buried under closed conjunctiva were used instead of the exposed long muscle and sliding noose sutures involved in the standard semiadjustable suture procedure; an additional temporary tracing suture facilitated the retrieval of the buried muscle suture loop during adjustment.

Results: Fifty-three consecutive patients (57 rectus extraocular muscles) underwent recession with the modified semiadjustable short loop technique. The mean age was 44.5 years (range: 16-81) and mean follow-up time 8.8 months (range 1.5-28 months). Postoperative adjustment was carried out in 21 patients (39.6%). In the remaining 32 patients, cutting and removing the exposed tracing suture and the nonabsorbable traction suture was the only necessary postoperative maneuver. Five cases of persistent conjunctival hyperemia, two cases of conjunctival dehiscence and two cases with a clinically significant delle were noted; all responded to topical treatment. There were no cases of suspected muscle slippage.

Conclusions: The short loop modification of the semiadjustable suture procedure allowed for postoperative adjustment while offering the benefit of minimal manipulation for the majority of cases in which adjustment was unnecessary. No major complications in conjunctival incision or extraocular muscle healing were encountered.

目的:提出一种半可调节缝合技术的改进方案,允许选择性调节。方法:采用埋在闭合结膜下的短缝线环代替标准半可调节缝线中暴露的长肌和滑动套索缝线;额外的临时追踪缝线有助于在调整期间收回埋藏的肌肉缝线环。结果:连续53例患者(57块眼外直肌)采用改良的半可调节短环技术进行了后屈。平均年龄44.5岁 年(范围:16-81),平均随访时间8.8 月(1.5-28 月)。21名患者(39.6%)进行了术后调整。在其余32名患者中,切割并移除暴露的追踪缝线和不可吸收的牵引缝线是唯一必要的术后操作。观察到5例持续性结膜充血,2例结膜开裂,2例有临床意义的水肿;所有患者均对局部治疗有反应。没有疑似肌肉滑脱的病例。结论:半可调节缝线程序的短环改良允许术后调整,同时为大多数不需要调整的病例提供了最小操作的好处。结膜切口或眼外肌愈合未出现重大并发症。
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引用次数: 0
Managing Pediatric Cataract Patients - The Whole Story: Aphakic Contact Lenses in Children - Techniques and Challenges. 管理儿童白内障患者-全部故事:儿童失神隐形眼镜-技术和挑战。
Q3 Medicine Pub Date : 2023-10-02 Epub Date: 2023-11-06
Ronald Biernacki

Infantile cataract is one of the major causes of visual impairment in children. This article will discuss some of the techniques, challenges, complications, and compliance issues with aphakic contact lenses.

婴儿白内障是造成儿童视力损害的主要原因之一。本文将讨论无晶状体隐形眼镜的一些技术、挑战、并发症和依从性问题。
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引用次数: 0
Pediatric Cataract: Disparately Blinding Globally and in the United States 小儿白内障:全球和美国的致盲情况各不相同
Q3 Medicine Pub Date : 2023-10-02 DOI: 10.1080/2576117X.2023.2188838
Tessnim R. Ahmad, Alejandra G. de Alba Campomanes
ABSTRACT Childhood cataract is a complex condition requiring longitudinal care, including early diagnosis, timely referral to a specialist, early surgical intervention, and dedicated postoperative care. Adherence to refractive correction and amblyopia therapy are critical for visual rehabilitation, even months to years after the cataract is removed. We review the impact of the social determinants of health on each step in the visual rehabilitation pathway for children with congenital and infantile cataracts. Children from socioeconomically marginalized backgrounds are more likely to experience delays in access to care and utilization of surgical services. They are also less likely to adhere to amblyopia therapy, with corresponding decrements in visual outcomes. Additional sociocultural factors, including parental stress, self-efficacy, and health literacy, pose barriers for these children. Standardizing clinical roles, improving health communication, managing parental stress, and implementing systemic policy changes may alleviate socioeconomic disparities in outcomes for children with cataracts.
摘要 儿童白内障是一种复杂的疾病,需要长期护理,包括早期诊断、及时转诊到专科医生、早期手术干预和术后专门护理。坚持屈光矫正和弱视治疗对于视力康复至关重要,甚至在白内障摘除后的数月至数年也是如此。我们回顾了健康的社会决定因素对先天性白内障和婴幼儿白内障患儿视觉康复过程中每一步的影响。来自社会经济边缘化背景的儿童更有可能在获得护理和利用手术服务方面遇到延误。他们坚持弱视治疗的可能性也更小,视觉效果也会相应下降。其他社会文化因素,包括父母的压力、自我效能感和健康知识,也给这些儿童带来了障碍。规范临床角色、改善健康沟通、管理家长压力以及实施系统性政策变革,可减轻白内障患儿在治疗效果上的社会经济差异。
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引用次数: 0
The Prevalence of Astigmatism and Spectacle Wear in Polish Schoolchildren. 波兰学童散光和眼镜佩戴的流行程度。
Q3 Medicine Pub Date : 2023-10-02 Epub Date: 2023-08-01
Piotr Kanclerz, Natasza Bazylczyk, Carla Lanca

Introduction: Unilateral or asymmetric astigmatism is considered a principal refractive error leading to amblyopia and regular eye examinations should be carried out during childhood to prevent visual impairment. The aim of this study was to evaluate the prevalence of astigmatism and spectacle wear among Polish schoolchildren.

Methods: A cross sectional study was carried out in children aged 6 to 14 years old from 50 schools in Poland. The presence of astigmatism was assessed by non-cycloplegic autorefraction, and defined as a cylinder equal or greater than 0.75 D. Children were classified as living in urban or rural areas according to the school location. Spectacle wear was defined as having spectacles at school.

Results: The study included 1041 children and 52.3% were girls (n = 544). The mean age was 8.62 ± 2.04 years. The prevalence of astigmatism was 7.3% (95% confidence interval [CI]: 5.8-9.1%). Only 21.7% of children with astigmatism wore spectacles at school. Astigmatism was diagnosed in 8.2% of boys (95% CI: 6.0-11.0%) and 6.4% of girls (95% CI: 4.5-8.8%; p = .13); cylindrical anisometropia was present in 19/76 (25.0%) of children with astigmatism (95% CI: 15.8%-36.3%). Against-the-rule astigmatism was the most common; it was observed in 48.7% of children with astigmatism, followed by with-the-rule astigmatism (44.7%) and oblique astigmatism (6.6%). The prevalence of astigmatism was not linearly correlated with age (r = 0.24; p = .53). Gender, age and place of living were not significantly associated with the presence of astigmatism.

Conclusions: This study reports a low prevalence of astigmatism in Polish school children. However, the majority of children with astigmatism were uncorrected. Further longitudinal studies are warranted.

简介:单侧或不对称散光被认为是导致弱视的主要屈光不正,儿童时期应定期进行眼部检查,以防止视力受损。本研究的目的是评估波兰学童散光和佩戴眼镜的患病率。方法:对6-14岁儿童进行横断面研究 来自波兰50所学校的50岁学生。散光的存在是通过非睫状肌麻痹自动屈光来评估的,并定义为等于或大于0.75 D的圆柱体。根据学校所在地,儿童被归类为生活在城市或农村地区。戴眼镜被定义为在学校戴眼镜。结果:本研究包括1041名儿童和52.3%的女孩(n = 544)。平均年龄8.62岁 ± 2.04 年。散光的患病率为7.3%(95%置信区间[CI]:5.8-9.1%)。只有21.7%的散光儿童在学校戴眼镜。8.2%的男孩(95%CI:6.0-11.0%)和6.4%的女孩(95%CI:4.5-8.8%;p = .13) ;76例散光患儿中有19例(25.0%)存在柱状屈光参差(95%CI:15.8%-36.3%),其中散光最常见;儿童散光发生率为48.7%,其次为规则散光(44.7%)和斜视散光(6.6%) = 0.24;p = .53)。性别、年龄和居住地与散光的存在没有显著相关性。结论:本研究报告了波兰学童散光的低患病率。然而,大多数患有散光的儿童是未经矫正的。需要进一步的纵向研究。
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引用次数: 0
Glaucoma Following Cataract Surgery: Pearls for Success Manuscript from the 2022 AOC/AACO/AAO Sunday Symposium 白内障手术后青光眼:成功秘诀 2022 年 AOC/AACO/AAO 周日研讨会手稿
Q3 Medicine Pub Date : 2023-10-02 DOI: 10.1080/2576117X.2023.2227552
Raymond G Areaux
ABSTRACT Glaucoma Following Cataract Surgery (GFCS) remains a menace, so parents must be counseled prior to cataract removal in children. Age less than 7 months at the time of surgery increases this risk, and IOL placement has no effect. To lower IOP in GFCS, start with drops and before you escalate to surgery, consider phospholine iodide. Then, proceed cautiously with angle surgery and shunts, mixing in cycloablative procedures where appropriate in your hands. With patient-centered models for access, follow-up & adherence to treatment, GFCS can be controlled. Partnering with our certified orthoptist colleagues, we can achieve excellent results for the “whole patient” spanning cataracts, glaucoma, strabismus, and amblyopia.
摘要 白内障手术后青光眼(GFCS)仍然是一种威胁,因此必须在儿童白内障摘除术前向家长提供咨询。手术时年龄小于 7 个月会增加这种风险,而人工晶体植入术没有任何效果。要降低 GFCS 患儿的眼压,首先要使用滴眼液,在升级到手术之前,可以考虑使用碘化磷脂。然后,谨慎地进行房角手术和分流术,在适合的情况下混合使用环形剥脱术。通过以患者为中心的就诊、随访和坚持治疗模式,GFCS 是可以得到控制的。我们与经过认证的视光矫治师同行合作,可以为白内障、青光眼、斜视和弱视等 "整个患者 "取得卓越的治疗效果。
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引用次数: 0
Indications for Systemic and Genetic Testing in Patients with Congenital Cataracts. 先天性白内障患者的系统和基因检测适应症。
Q3 Medicine Pub Date : 2023-10-02 Epub Date: 2023-11-06
Reem Amine, Elias I Traboulsi

Congenital cataracts account for a significant proportion of blindness in children worldwide. They affect approximately 12-136 per 100,000 births worldwide. A genetic etiology is present in a large proportion of patients and can lead to isolated cataracts or those in the context of genetic multisystem disorders. We present two examples of genetically determined childhood cataracts and briefly review the work-up of such patients. Mutations in numerous genes have been identified that cause congenital cataracts, such as those encoding for crystallins, connexins and aquaporins, as well as some developmental regulatory proteins. Identifying the genetic or molecular etiology of congenital cataract is essential for identifying and better understanding the pathways leading to this disease, and for providing individualized genetic counseling and guiding treatment for possible associated systemic problems.

先天性白内障在全世界儿童失明中占很大比例。全世界每100000名新生儿中约有12-136人受到影响。遗传病因存在于很大一部分患者中,可导致孤立性白内障或遗传性多系统疾病。我们介绍了两个由基因决定的儿童白内障的例子,并简要回顾了这些患者的治疗情况。已经鉴定出许多导致先天性白内障的基因突变,例如编码结晶蛋白、连接蛋白和水通道蛋白以及一些发育调节蛋白的基因。识别先天性白内障的遗传或分子病因对于识别和更好地了解导致该疾病的途径,以及为可能相关的系统性问题提供个性化的遗传咨询和指导治疗至关重要。
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引用次数: 0
Role of Intraocular Lens Implantation in Children. 儿童人工晶状体植入术的作用。
Q3 Medicine Pub Date : 2023-10-02 Epub Date: 2023-11-06
Erick D Bothun

Purpose: To summarize recent literature and provide an update on the role of intraocular lens implantation in children.

Design: AOC/AACO/AAO 2022 Symposium Summary.

Intervention: None.

Results: Literature review surrounding the use of intraocular lenses in children. Attention was given to multicenter study efforts including the Infant Aphakia Treatment Study, the Toddler Aphakia and Pseudophakia Study, and the Pediatric Eye Disease Investigator Group Cataract Registry.

Conclusions: Intraocular lenses are a valuable tool in the care of children with lens abnormalities. Recent studies and advancements in fixation techniques have complimented our care and highlighted age and ocular dependent risks. Thorough initial clinical assessment and long-term postoperative management are critical in maximizing outcomes.

目的:总结最近的文献,并提供最新的儿童人工晶状体植入的作用。设计:AOC/AACO/AAO 2022研讨会总结。干预:无。结果:关于儿童人工晶状体使用的文献综述。关注多中心研究工作,包括婴儿失神治疗研究、幼儿失神和假性白内障研究以及儿童眼病研究者组白内障登记。结论:人工晶状体是治疗晶状体异常儿童的宝贵工具。最近的研究和固定技术的进步赞扬了我们的护理,并强调了年龄和眼部依赖性风险。彻底的初步临床评估和长期的术后管理对于最大限度地提高疗效至关重要。
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引用次数: 0
Indications for Systemic and Genetic Testing in Patients with Congenital Cataracts 先天性白内障患者接受系统检测和基因检测的指征
Q3 Medicine Pub Date : 2023-10-02 DOI: 10.1080/2576117X.2023.2229812
Reem Amine, Elias I Traboulsi
ABSTRACT Congenital cataracts account for a significant proportion of blindness in children worldwide. They affect approximately 12–136 per 100,000 births worldwide. A genetic etiology is present in a large proportion of patients and can lead to isolated cataracts or those in the context of genetic multisystem disorders. We present two examples of genetically determined childhood cataracts and briefly review the work-up of such patients. Mutations in numerous genes have been identified that cause congenital cataracts, such as those encoding for crystallins, connexins and aquaporins, as well as some developmental regulatory proteins. Identifying the genetic or molecular etiology of congenital cataract is essential for identifying and better understanding the pathways leading to this disease, and for providing individualized genetic counseling and guiding treatment for possible associated systemic problems.
摘要 先天性白内障在全球儿童失明中占很大比例。全球每 10 万名新生儿中约有 12 至 136 人患有先天性白内障。大部分患者的病因与遗传有关,可能导致孤立的白内障,也可能导致遗传性多系统疾病。我们列举了两个由遗传因素导致的儿童白内障的病例,并简要回顾了此类患者的检查方法。目前已发现许多基因突变会导致先天性白内障,如编码晶体蛋白、连接蛋白和水汽蛋白的基因,以及一些发育调节蛋白。确定先天性白内障的遗传或分子病因对于确定和更好地了解导致这种疾病的途径、提供个体化遗传咨询和指导治疗可能相关的系统性问题至关重要。
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引用次数: 0
期刊
Journal of Binocular Vision and Ocular Motility
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