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Prevalence, serotype distribution, and antimicrobial susceptibility profile of Streptococcus pneumoniae among patients with acute respiratory tract infection 急性呼吸道感染患者肺炎链球菌的患病率、血清型分布及抗菌药物敏感性分析
Q2 Medicine Pub Date : 2021-07-01 DOI: 10.4103/WHO-SEAJPH.WHO-SEAJPH_58_21
D. Safari, N. Widhidewi, W. Paramaiswari, Anak Lila Paramasatiari, H.F. Maharani Putri, I. A. Asih Ratnadi, I. Agus Sastrawan
We investigated the nasopharyngeal (NP) carriage and antimicrobial susceptibility profile of Streptococcus pneumoniae among adults and children with acute respiratory tract infection (ARTI). NP swabs were collected from ARTI patients in Tabanan, Bali, Indonesia, in 2017. Serotyping of S. pneumoniae and antibiotic susceptibility profile were performed by multiplex sequential PCR and the disk diffusion method, respectively. Out of 200 ARTI patients, S. pneumoniae strains were carried by 22.6% and 2.4% of children (36/159) and adults (1/41), respectively. Serotype 6A/6B was the most common serotype among cultured strains (21%) followed by 19F (18%) and 14 (8%). Most isolates were susceptible to chloramphenicol (87%), followed by clindamycin (74%), erythromycin (72%), sulfamethoxazole-trimethoprim (59%), and tetracycline (44%). This finding provides baseline information on the serotype distribution of S. pneumoniae carriage among ARTI patients in Indonesia.
我们调查了急性呼吸道感染(ARTI)成人和儿童中肺炎链球菌的鼻咽部携带和抗菌药物敏感性。2017年从印度尼西亚巴厘岛塔巴南的ARTI患者中收集NP拭子。采用多重序列PCR和纸片扩散法分别进行肺炎链球菌血清分型和抗生素药敏分析。在200例ARTI患者中,儿童(36/159)和成人(1/41)携带肺炎链球菌的比例分别为22.6%和2.4%。血清型以6A/6B型最多(21%),其次为19F型(18%)和14型(8%)。对氯霉素敏感的菌株最多(87%),其次是克林霉素(74%)、红霉素(72%)、磺胺甲恶唑-甲氧苄啶(59%)和四环素(44%)。这一发现提供了印度尼西亚抗逆转录病毒治疗患者中肺炎链球菌血清型分布的基线信息。
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引用次数: 1
Emergency alert for philippine education! Exploring the negative impact of prolonged cancellation of in-person schooling 菲律宾教育紧急警报!探讨长期取消面对面教育的负面影响
Q2 Medicine Pub Date : 2021-07-01 DOI: 10.4103/WHO-SEAJPH.WHO_SEAJPH_233_21
Dalmacito A. Cordero
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引用次数: 0
Factors associated with anxiety and depression among chronic obstructive pulmonary disease outpatients in Ho Chi Minh City, Vietnam 越南胡志明市慢性阻塞性肺疾病门诊患者的焦虑和抑郁相关因素
Q2 Medicine Pub Date : 2021-07-01 DOI: 10.4103/WHO-SEAJPH.WHO_SEAJPH_149_21
Nhung Quynh Nguyen, Van Ngoc Huynh, Q. To, K. To
This study investigates the prevalence of and associated factors with depression and anxiety among chronic obstructive pulmonary disease (COPD) outpatients at Pham Ngoc Thach Hospital, Ho Chi Minh City, Vietnam. A cross-sectional study was conducted between March and May 2020 at the hospital's outpatient department. Those aged ≥18 years, diagnosed with COPD and undergoing COPD treatment, were eligible. The Hospital Anxiety and Depression Scale was used to measure depression and anxiety. Dyspnea was assessed using the modified Medical Research Council (mMRC) dyspnea scale. Among 392 patients, 381 (97%) participated in the study. The number of patients with depression and anxiety was 33.1% and 21.3%, respectively. Compared to men, women were more likely to experience depression (adjusted odds ratio [aOR] = 2.12, 95% confidence interval [CI] = 1.06–4.24) and anxiety (aOR = 4.11, 95% CI = 1.90–8.87). Those not having caregivers were more likely to experience depression (aOR = 3.03, 95% CI = 1.27–7.20) and anxiety (aOR = 3.47, 95% CI = 1.26–9.60). Having mMRC dyspnea scale ≥2 was associated with higher odds of experiencing depression (aOR = 5.94, 95% CI = 3.63–9.72) and anxiety (aOR = 6.78, 95% CI = 3.48–13.18). Those not adhering to medication treatment (aOR = 2.32, 95% CI = 1.15–4.70) and having comorbidity (aOR = 2.02, 95% CI = 1.10–3.73) were more likely to experience anxiety. Routine screening of COPD patients for depression and anxiety is necessary so that early interventions could be provided.
本研究调查了越南胡志明市范玉达医院慢性阻塞性肺疾病(COPD)门诊患者抑郁和焦虑的患病率及其相关因素。2020年3月至5月期间,在医院门诊部进行了一项横断面研究。年龄≥18岁,诊断为COPD并正在接受COPD治疗的患者入选。采用医院焦虑抑郁量表对抑郁和焦虑进行测量。呼吸困难采用改良的医学研究委员会(mMRC)呼吸困难量表进行评估。在392例患者中,381例(97%)参加了研究。抑郁和焦虑患者分别占33.1%和21.3%。与男性相比,女性更容易经历抑郁(调整优势比[aOR] = 2.12, 95%可信区间[CI] = 1.06-4.24)和焦虑(aOR = 4.11, 95% CI = 1.90-8.87)。那些没有照顾者的人更有可能经历抑郁(aOR = 3.03, 95% CI = 1.27-7.20)和焦虑(aOR = 3.47, 95% CI = 1.26-9.60)。mMRC呼吸困难量表≥2与出现抑郁(aOR = 5.94, 95% CI = 3.63-9.72)和焦虑(aOR = 6.78, 95% CI = 3.48-13.18)的几率较高相关。那些不坚持药物治疗(aOR = 2.32, 95% CI = 1.15-4.70)和有合并症(aOR = 2.02, 95% CI = 1.10-3.73)的人更容易感到焦虑。对慢性阻塞性肺病患者进行抑郁和焦虑的常规筛查是必要的,以便提供早期干预措施。
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引用次数: 0
Availability and delivery of cardiac rehabilitation in South-East Asia: How does it compare globally? 东南亚心脏康复的可得性和交付:与全球相比如何?
Q2 Medicine Pub Date : 2021-07-01 DOI: 10.4103/WHO-SEAJPH.WHO-SEAJPH_62_21
Mohiul Chowdhury, Fiorella A Heald, K. Turk-Adawi, M. Supervia, A. Babu, B. Radi, S. Grace
Background: The aims of this study were to establish cardiac rehabilitation (CR) availability and density, as well as the nature of programs in South-East Asian Region (SEAR) countries, and to compare this with other regions globally. Methods: In 2016/2017, the International Council of Cardiovascular Prevention and Rehabilitation engaged cardiac associations to facilitate program identification globally. An online survey was administered to identify programs using REDCap, assessing capacity and characteristics. CR density was computed using Global Burden of Disease study annual ischemic heart disease (IHD) incidence estimates. The program audit was updated in 2020. Results: CR was available in 6/11 (54.5%) SEAR countries. Data were collected in 5 countries (83.3% country response); 32/69 (68.1% response rate from 2016/2017) programs completed the survey. These data were compared to 1082 (32.1%) programs in 93/111 (83.3%) countries with CR. Across SEAR countries, there was only one CR spot per 283 IHD patients (vs. 12 globally), with an unmet regional need of 4,258,968 spots annually. Most programs were in tertiary care centers (n = 25, 78.1%; vs. 46.1% globally, P < 0.001). Most were funded privately (n = 17, 56.7%; vs. 17.9%, P < 0.001), and 22 (73.3%) patients were paying out of pocket (vs. 36.2% globally; P < 0.001). The mean number of staff on the multidisciplinary teams was 5.5 ± 3.0 (vs. 5.9 ± 2.8 globally P = 0.268), offering 8.6 ± 1.7/11 core components (consistent with other countries) over 16.8 ± 12.6 h (vs. 36.2 ± 53.3 globally, P = 0.01). Conclusion: Funded CR capacity must be augmented in SEAR. Where available, services were consistent with guidelines, and other regions of the globe, despite programs being shorter than other regions.
背景:本研究的目的是建立心脏康复(CR)的可用性和密度,以及东南亚地区(SEAR)国家项目的性质,并将其与全球其他地区进行比较。方法:2016/2017年,国际心血管预防与康复理事会与心脏协会合作,促进全球项目识别。我们进行了一项在线调查,以确定使用REDCap的项目,评估其能力和特点。利用全球疾病负担研究年度缺血性心脏病(IHD)发病率估计计算CR密度。该计划审计于2020年进行了更新。结果:6/11个(54.5%)SEAR国家有CR。在5个国家收集了数据(83.3%的国家响应);32/69个项目(2016/2017年回复率为68.1%)完成了调查。这些数据与93/111个CR国家的1082个(32.1%)项目进行了比较。在SEAR国家,每283名IHD患者只有一个CR点(全球为12个),每年未满足的区域需求为4,258,968个。大多数项目在三级保健中心(n = 25, 78.1%;全球46.1%,P < 0.001)。大多数是私人资助的(n = 17, 56.7%;17.9%, P < 0.001), 22名(73.3%)患者自费支付(全球为36.2%;P < 0.001)。多学科团队的平均人数为5.5±3.0人(全球为5.9±2.8人,P = 0.268),在16.8±12.6小时内提供8.6±1.7/11个核心部件(与其他国家一致)(全球为36.2±53.3人,P = 0.01)。结论:SEAR必须提高资助CR能力。在可用的情况下,服务与指导方针和全球其他区域一致,尽管项目比其他区域短。
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引用次数: 0
Perceptions of barriers to addressing pharmaceutical stockout in timor-leste 对解决东帝汶药品短缺问题障碍的认识
Q2 Medicine Pub Date : 2021-07-01 DOI: 10.4103/WHO-SEAJPH.WHO_SEAJPH_54_21
Lourenço Camnahas, E. Willis, P. Dettwiller, J. Shipman
Background: Since 2005, stockout of pharmaceuticals has been a constant issue at all health services in Timor-Leste (TL). Aim: This study identifies factors that contribute to the ongoing pharmaceutical stockout as perceived by various stakeholders. Methods: A mixed-method approach was implemented, including face-to-face interviews with 46 Timorese health professionals involved in the pharmaceutical supply chain, along with documentational review and analysis. The field study was conducted in four locations (Dili, Liquiça, Aileu, and Ermera) from July to October 2018. This paper draws on qualitative accounts of participants' perceptions, which were investigated through an interview schedule in the Tetum language, with transcripts translated into English for analysis. Results: The responses gathered were consistent among various groups of employees. Perceptions of stakeholder views on factors contributing to pharmaceutical stockout were identified. These included issues such as poor coordination, failure to adhere to policy guidelines, significant difficulties, and lack of knowledge with inventory management, quantification, forecasting, and budgetary constraints. A weak logistic management information system and a lack of capacity in inventory management resulted in a lack of reliable data. Other factors, such as political intervention, work ethics and lack of basic infrastructure, such as internet connectivity, were also reported by participants. Conclusion: The findings highlighted that there are multiple factors contributing to the ongoing pharmaceutical stockout. This may be addressed by implementing more culturally appropriate education and training on forecasting methods.
背景:自2005年以来,药品缺货一直是东帝汶所有保健服务机构的一个经常性问题。目的:本研究确定的因素,有助于持续的药品缺货被各种利益相关者感知。方法:采用混合方法,包括与46名参与药品供应链的东帝汶卫生专业人员进行面对面访谈,并进行文献审查和分析。实地研究于2018年7月至10月在四个地点(帝力、利基帕拉、阿伊柳和埃梅拉)进行。本文借鉴了参与者感知的定性描述,通过德顿语的访谈时间表进行了调查,并将笔录翻译成英语进行分析。结果:收集到的回答在不同的员工群体中是一致的。确定了利益相关者对导致药品缺货的因素的看法。这些问题包括协调不良、未能坚持政策指导方针、重大困难以及缺乏库存管理、量化、预测和预算限制方面的知识。物流管理信息系统薄弱,库存管理能力不足,导致缺乏可靠的数据。参与者还报告了其他因素,如政治干预、职业道德和缺乏基础设施,如互联网连接。结论:研究结果表明,造成药品缺货的因素多种多样。这可以通过实施更适合文化的预测方法教育和培训来解决。
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引用次数: 0
Financing health in the new normal: issues and opportunities 新常态下的卫生筹资:问题与机遇
Q2 Medicine Pub Date : 2021-02-01 DOI: 10.4103/2224-3151.309875
Soonman Kwon
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引用次数: 0
Roles of community health workers in advancing health security and resilient health systems: emerging lessons from the COVID-19 response in the South-East Asia Region 社区卫生工作者在促进卫生安全和有复原力的卫生系统中的作用:东南亚区域应对COVID-19的新经验
Q2 Medicine Pub Date : 2021-02-01 DOI: 10.4103/2224-3151.309872
S. Bezbaruah, Polly Wallace, M. Zakoji, Wagawatta Padmini Perera, Masaya Kato
To enhance public health emergency preparedness, countries have strengthened core capacities required by the International Health Regulations (2005). In addition, recent major public health emergencies, including the coronavirus disease 2019 (COVID-19) pandemic, have reiterated the critical importance of underlying health systems and their resilience, including the roles of community health workers (CHWs). The aim of this study was to summarize the situation of CHWs in the World Health Organization South-East Asia Region, including their roles and the challenges they have faced during the COVID-19 pandemic response. We reviewed journal articles, policy documents, national guidelines, reports and online publications from development agencies, governments and media houses. Our review results, including three identified case studies, suggest that CHWs in the region have expanded their usual roles to meet the need for both maintenance of regular health services and demand for COVID-19 response activities. During the response, the regular role of a CHW in health education and promotion focused on awareness-raising and the promotion of “new normal” behaviours; CHWs also played critical roles in assisting in surveillance and contact tracing, and in ensuring that people followed isolation and quarantine guidelines. Concurrently, CHWs ensured continuity of essential health services. However, there were challenges, such as stigma, a lack of adequate training or protective equipment, and limited levels of incentives and recognition. Based on these findings, we recommend the development and implementation of long-term plans across the region to strengthen and support CHWs and recognize CHWs as an integral component of resilient health systems. Planning for CHWs as part of the primary health care system will enable local authorities to ensure that an adequate level of resources (including capacity-building, incentives, necessary equipment and consumables) is allocated to CHWs.
为了加强突发公共卫生事件的准备,各国加强了《国际卫生条例(2005)》所要求的核心能力。此外,最近发生的重大突发公共卫生事件,包括2019年冠状病毒病(COVID-19)大流行,重申了基础卫生系统及其复原力的至关重要性,包括社区卫生工作者的作用。本研究的目的是总结世界卫生组织东南亚地区卫生工作者的情况,包括他们在COVID-19大流行应对过程中的作用和面临的挑战。我们审查了来自发展机构、政府和媒体机构的期刊文章、政策文件、国家指南、报告和在线出版物。我们的审查结果(包括三个已确定的案例研究)表明,该地区的卫生保健员已经扩大了其通常的作用,以满足维持常规卫生服务的需求和对COVID-19应对活动的需求。在应对期间,保健女工在健康教育和促进方面的常规作用侧重于提高认识和促进"新常态"行为;在协助监测和追踪接触者,以及确保人们遵守隔离和检疫准则方面,卫生工作者也发挥了重要作用。同时,保健员确保基本保健服务的连续性。然而,也存在一些挑战,例如耻辱,缺乏适当的培训或防护设备,以及奖励和认可程度有限。基于这些发现,我们建议在整个地区制定和实施长期计划,以加强和支持卫生保健工作者,并认识到卫生保健工作者是有复原力的卫生系统的一个组成部分。将卫生保健室作为初级卫生保健系统的一部分进行规划,将使地方当局能够确保向卫生保健室分配足够的资源(包括能力建设、激励措施、必要的设备和消耗品)。
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引用次数: 15
Decentralization of India Hypertension Control Initiative services to maintain continuum of care for hypertensive patients during COVID-19 pandemic in Telangana 印度高血压控制倡议下放服务,以便在特伦甘纳邦COVID-19大流行期间维持对高血压患者的持续护理
Q2 Medicine Pub Date : 2021-02-01 DOI: 10.4103/2224-3151.309873
Kiran Durgad, TSravan Kumar Reddy, A. Kunwar, F. Tullu, Chintala Sreedhar, Abdul Wassey, A. Pathni, L. Swasticharan, Meenakshi Sharma, M. Madhavi
The India Hypertension Control Initiative (IHCI) was launched in Telangana, India, with the vision of maintaining the continuum of care for hypertensive patients and improving treatment outcomes through provision of free hypertension medication. Decentralization of the IHCI towards more patient-centred services was undertaken to bring free medication and follow-up services closer to the community in the hopes of improving follow-up and control rates for hypertensive patients. To determine if decentralization of hypertension follow-up services and free medication to peripheral health centres improved continuity of care and treatment outcomes in hypertensive patients and helped to mitigate disruption during the coronavirus disease 2019 (COVID-19) pandemic, hypertension outcomes were reviewed before and during the COVID-19 pandemic, for patients registered in health centres that decentralized free medication and follow-up services to subcentres – the intervention group – and in health centres that did not decentralize these services – the non-intervention group. Hypertensive patients had higher rates of monthly follow-up and controlled blood pressure in the decentralized facilities than in the non-decentralized facilities, where these services were limited to primary and secondary health centres. Comparing follow-up rates and blood pressure control rates before and during the COVID-19 pandemic, these were maintained for patients in the decentralized facilities whereas they were significantly lower for patients in the non-decentralized facilities. The IHCI decentralized model appears to have contributed to continuity of care for people with hypertension and to have maintained this continuity against system shocks such as that of the COVID-19 pandemic. Decentralization of free medicines and follow-up services to the first and most peripheral point of contact in the primary health care system brings these essential services closer to home, which can encourage patients to seek services from the public sector – capturing a strong case for a primary health care foundation to the strengthening of systems for universal health coverage.
印度高血压控制倡议(IHCI)在印度特伦加纳邦启动,其愿景是通过提供免费高血压药物,维持对高血压患者的连续护理,并改善治疗结果。为了使免费药物治疗和后续服务更接近社区,已将综合医疗保健服务的权力下放,使其更加以病人为中心,以期提高高血压病人的后续治疗和控制率。为了确定高血压随访服务的分散和向周边卫生中心提供免费药物是否改善了高血压患者护理和治疗结果的连续性,并有助于减轻2019冠状病毒病(COVID-19)大流行期间的中断,研究人员在2019冠状病毒病大流行之前和期间对高血压结果进行了审查。对于在将免费药物和后续服务下放到次级中心的保健中心登记的患者,即干预组,而在未将这些服务下放到次级中心的保健中心登记的患者,即非干预组。与非分散医疗机构相比,分散医疗机构的高血压患者每月随访率和血压控制率更高,而非分散医疗机构的服务仅限于初级和二级医疗中心。对比2019冠状病毒病大流行之前和期间的随访率和血压控制率,分散医疗机构的患者保持了随访率和血压控制率,而非分散医疗机构的患者则明显较低。IHCI的分散模式似乎有助于对高血压患者的连续性护理,并在应对COVID-19大流行等系统冲击时保持了这种连续性。将免费药品和后续服务下放到初级卫生保健系统的第一个和最外围的接触点,使这些基本服务更接近家庭,这可以鼓励患者向公共部门寻求服务——为加强全民健康覆盖系统提供初级卫生保健基础的有力理由。
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引用次数: 6
Pandemic preparedness requires better regulation and stewardship of private providers that dominate provision of primary health care 大流行防范需要对主导初级卫生保健提供的私营提供者进行更好的监管和管理
Q2 Medicine Pub Date : 2021-02-01 DOI: 10.4103/2224-3151.309874
M. Khan, Afifah Rahman-Shepherd, Nina van der Mark, O. Dar, R. Hasan
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引用次数: 0
Emerging good practices and lessons learnt to maintain essential health services during the COVID-19 pandemic 在COVID-19大流行期间维持基本卫生服务的新出现的良好做法和经验教训
Q2 Medicine Pub Date : 2021-02-01 DOI: 10.4103/2224-3151.309868
M. Zakoji, T. Sundararaman
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引用次数: 11
期刊
WHO South-East Asia journal of public health
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