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Impaction bone grafting as a method of choice in bone defect management in the revision hip arthroplasty: a cases series 作为翻修髋关节置换术骨缺损处理首选方法的撞击植骨术:系列病例
Q3 Medicine Pub Date : 2024-04-21 DOI: 10.18019/1028-4427-2024-30-2-245-254
V. Golnik, V. A. Peleganchuk, D. A. Dzhukhaev, Yu.M. Batrak, V. V. Pavlov
Introduction Reconstruction of the acetabulum during revision arthroplasty is a challenging task in the setting of massive bone defects. Often the only effective method is impaction bone grafting (IBG). The purpose is to demonstrate the capabilities of the X-Change impaction bone grafting technology in replacing acetabular defects as a method of choice for revision hip arthroplasty.Materials and methods In the presented series of cases, the use (IBG) turned out to be the method of choice, allowing for high-quality reconstruction. In each presented case, revision hip arthroplasty was performed with augmentation with a reconstructive mesh or trabecular metal augment to create support and contain the defect to retain the osteoplastic material.Results During follow-up periods of 4.8 to 6.5 years there were no signs of resorption or loosening. According to the Harris hip score the results were 96, 97 and 89 points respectively.Discussion Impaction bone grafting technology is quite versatile. It can be used in various coditions of revision arthroplasty with contained defects of the acetabulum. In contrast to the use of modular revision augmentation systems and additive technologies it makes possible to achieve dense filling of the smallest defects and profile a bed congruent with the acetabular component. The use of cemented fixation makes it possible to further stabilize the impacted bone chips and use mechanotransduction mechanisms that  stimulate the bone remodeling. The use of IBG has proven to be an effective technique for the reconstruction of medium-sized acetabular defects in combination with mesh and cement cup, as well as in combination with trabecular metal augments.Conclusion The use of IBG during revision hip arthroplasty can be especially effective for small acetabulum sizes. Combining IBG with trabecular metal augments significantly expands the application of this technology. The use of IBG makes it possible to create a bone reserve, which creates more favorable conditions for inevitable repeated revision interventions.
引言 在翻修关节置换术中重建髋臼是一项在大量骨缺损情况下极具挑战性的任务。通常情况下,唯一有效的方法就是撞击植骨(IBG)。本文旨在展示 X-Change 撞击植骨技术作为翻修髋关节置换术的首选方法,在置换髋臼缺损方面的能力。 材料和方法 在所介绍的一系列病例中,IBG 被证明是首选方法,可以实现高质量的重建。在每个病例中,翻修髋关节置换术都使用了重建网状物或小梁金属隆起物,以形成支撑并控制缺损,保留骨整形材料。结果 在 4.8 至 6.5 年的随访期间,没有出现吸收或松动迹象。根据 Harris 髋关节评分,结果分别为 96 分、97 分和 89 分。它可用于各种髋臼包含性缺损的翻修关节成形术。与使用模块化翻修增量系统和添加剂技术相比,它可以对最小的缺损进行致密填充,并形成与髋臼组件一致的骨床轮廓。使用骨水泥固定可进一步稳定受冲击的骨片,并利用机械传导机制刺激骨重塑。事实证明,使用 IBG 与网片和骨水泥髋臼杯相结合,以及与骨小梁金属增量相结合,是重建中等大小髋臼缺损的有效技术。将 IBG 与小梁金属隆起相结合,可大大扩展该技术的应用范围。使用 IBG 可以建立骨储备,为不可避免的反复翻修手术创造更有利的条件。
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引用次数: 0
Comparative analysis of the methods of an all-endoscopic brachial plexus decompression and a mini-invasive endoscopically-assisted technique for management of patients with traumatic brachioplexopathy 治疗外伤性肱神经丛病患者的全内窥镜臂丛神经减压术和微创内窥镜辅助技术的方法比较分析
Q3 Medicine Pub Date : 2024-04-19 DOI: 10.18019/1028-4427-2024-30-2-171-181
E. Belyak, R. K. Sagdiev, F. L. Lazko, A. A. Sufianov, D. L. Paskhin, A. Prizov, M. Lazko, N. V. Zagorodniy
Introduction As reported, brachioplexopathy is a relevant polyetiological disease with an annual incidence from 0.17 to 1.6 per 100,000. There are two basic endoscopic methods of brachial plexus decompression: an  endoscopically-assisted mini-invasive transaxillary approach and fully endoscopic decompression in association with shoulder arthroscopy.Purpose Compare the two main endoscopic methods of brachial plexus decompression.Material and methods Twenty-two patients diagnosed with post-traumatic brachioplexopathy were included in the study. There were 8 patients in group 1 and 14 patients in group 2. All patients passed clinical and instrumental examination. Statistical analysis was performed with non-parametric U-criteria of  Mann – Whitney. Differences were considered significant at p < 0.05. Patients of group 1 underwent shoulder joint arthroscopy and fully endoscopic brachial plexus decompression. Patients of group 2 had revision and transaxillary mini-invasive decompression of brachial plexus with video endoscopic assistance.Results In the first group, upper limb dysfunction according to DASH scale decreased from 52.3 ± 2.2 to 28.8 ± 3.8 points (p < 0.05). In the second group, upper limb dysfunction according to DASH scale decreased from 47.9 ± 4.4 to 26.6 ± 4.3 points (p < 0.05). Discrepancy according to DASH scale before and after surgery in the first group was 23.5 ± 3.6 points and in the second group it was 19.4 ± 5.4 points; the difference between the groups was statistically insignificant (p > 0.05).Discussion The results of our study are similar to the results of endoscopic brachial plexus decompression in the previously published studies.Conclusion The methods of endoscopic brachial plexus decompression in association with shoulder joint arthroscopy and isoolated mini-invasive neurolysis and decompression of brachial plexus under videoendoscopic assistance are equally effective in the treatment of brachialplexopathy.
导言 据报道,臂丛神经病是一种相关的多病因疾病,年发病率为十万分之0.17至1.6。臂丛神经减压术有两种基本的内窥镜方法:一种是内窥镜辅助下的经腋窝微创方法,另一种是与肩关节镜联合使用的全内窥镜减压术。第一组有 8 名患者,第二组有 14 名患者。所有患者均通过了临床和仪器检查。统计分析采用曼-惠特尼非参数 U 标准。P<0.05为差异显著。第一组患者接受了肩关节镜检查和全内窥镜臂丛神经减压术。结果 在第一组中,根据DASH量表,上肢功能障碍从52.3±2.2分降至28.8±3.8分(P<0.05)。在第二组中,DASH量表显示的上肢功能障碍从(47.9 ± 4.4)分下降到(26.6 ± 4.3)分(P < 0.05)。讨论 我们的研究结果与之前发表的研究中内镜臂丛神经减压术的结果相似。结论 内窥镜臂丛神经减压术与肩关节镜手术相结合,以及在视频内窥镜辅助下进行等温微创神经切断术和臂丛神经减压术,这两种方法在治疗臂丛神经病方面同样有效。
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引用次数: 0
Clinical and radiological aspects of the forearm in children with congenital radioulnar synostosis: a cohort study 先天性桡侧膝关节突触症儿童前臂的临床和放射学方面:一项队列研究
Q3 Medicine Pub Date : 2024-04-19 DOI: 10.18019/1028-4427-2024-30-2-182-190
Yulia A. Fedorova, S. V. Vissarionov, Y. Proshchenko, V. Zorin
Introduction The upper limb functional limitations in congenital radioulnar synostosis may significantly affect the daily activities of patients. Classifications of the condition are descriptive and have limited practical application.Purpose Determine a functionally significant quantitative criterion for anatomical changes in the forearm.Material and methods 92 children (136 forearms) with congenital radioulnar synostosis were examined for  limitations in activities of daily living (ADL), health-related quality of life measured with  PedsQL questionnaire; pronation of the forearm and radiographic parameters. A comparative and  correlation analysis, ROC analysis were performed to determine the relationship between the forearm pronation and limitations of ADL.Results Statistically significant correlations were revealed between symptoms and the forearm alignment (p < 0.01, rxy = 0.5); subluxation of the ulnar head and forearm alignment (p < 0.001, rxy = 0.6); bowing deformity of the radius, forearm alignment and subluxation of the ulnar head and between the length of the forearm bones and bowing deformity of the radius (p < 0.05, rxy = 0.4 and rxy = 0.5). A statistically significant inverse correlation was revealed between symptoms and PedsQL scores (p = 0.038, rxy = –0.4). Pronation of 45° was the threshold value of the forearm alignment with a high risk of ADL limitation. The area under the ROC curve corresponding to the relationship between symptoms and the forearm alignment was 0.955 ± 0.021 (95 % CI: 0.915–0.995). There was a statistically significant (p < 0.01) decrease in the lumen of the medullary canal in the middle third of the ulnar shaft with the radius lumen being unchanged. Dorsal subluxation of the ulnar head was detected In 30 % of cases.Discussion The characteristics identified demonstrated changes in the forearm bones with functional impairments being correlated with the forearm pronation.Conclusion The correlation between the patient’s symptoms and the forearm alignment must be taken into  account in the classification and when determining indications for surgical treatment distinguishing between functional (< 45° pronation) and dysfunctional (≥ 45° pronation) options.
导言:先天性桡侧膝关节突触症的上肢功能障碍可能会严重影响患者的日常活动。材料和方法 对 92 名先天性放射性桡侧与桡侧关节突触症患儿(136 个前臂)进行了日常生活活动(ADL)受限、健康相关生活质量(用 PedsQL 问卷测量)、前臂代偿和放射学参数的检查。为确定前臂前伸与 ADL 限制之间的关系,进行了比较和相关分析以及 ROC 分析。5);尺骨头半脱位与前臂排列(p < 0.001,rxy = 0.6);桡骨弓形畸形、前臂排列和尺骨头半脱位以及前臂骨骼长度与桡骨弓形畸形之间存在统计学意义上的显著相关性(p < 0.05,rxy = 0.4 和 rxy = 0.5)。症状与 PedsQL 评分之间存在统计学意义上的明显反相关性(p = 0.038,rxy = -0.4)。前臂前伸 45° 是导致 ADL 受限风险较高的前臂对齐临界值。症状与前臂对齐度之间关系的 ROC 曲线下面积为 0.955 ± 0.021(95 % CI:0.915-0.995)。尺骨中三分之一处的髓管腔在统计学上有明显的减少(p < 0.01),而桡骨的髓管腔则没有变化。结论 在分类和确定手术治疗适应症时,必须考虑患者症状与前臂排列之间的相关性,并区分功能性(前臂前伸<45°)和功能障碍(前臂前伸≥45°)两种选择。
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引用次数: 0
The long-term results of proximal interphalangeal joint arthroplasty of the hand 手部近端指间关节置换术的长期效果
Q3 Medicine Pub Date : 2024-04-19 DOI: 10.18019/1028-4427-2024-30-2-191-199
P. V. Fedotov, D. V. Kovalev, S. N. Rybakov
Introduction Small joints replacement is a valid treatment for deforming osteoarthritis and traumatic injuries to  the  phalangeal joints of the hand to restore motor hand functions. Various types of implants differing in shape, biomechanics and material composition have been developed.The purpose of the study was to evaluate long-term results of the proximal interphalangeal joint arthroplasty of the hand using various implants and identify their advantages.Material and methods We retrospectively reviewed 78 cases of proximal interphalangeal joint replacement in 64 patients. Outcomes were assessed at 6 months and at follow-up stages with preoperative and postoperative measurements of the range of motion in the joint evaluating pain, radiographs and outcomes measures using the Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire.Results The range of motion in the prosthetic joint increased significantly at different follow-up periods with all types of implants. The pain syndrome decreased. Radiographs revealed 10 cases of aseptic instability in  the  group of constrained prostheses. The DASH assessment showed high subjective satisfaction with the treatment.Discussion We could not find papers reporting PIP joint arthroplasty using SBI D.G.T. implant system. A retrospective study of RM Finger arthroplasty of the PIP joint indicated restored joint stability with AROM improvement and with low pain, although it had a high rate of complications. We recorded no complications with this implant model. Some authors would not recommend the RM Finger implant (Mathys) for PIP joint replacement. Arthroplasty of small joints of the hand with MOJE kermik-implantate showed satisfactory outcomes for 82 % of patients at a long term.Conclusion Arthroplasty of the PIP joint of the hand using various implant designs resulted in greater mobility of the upper limbs, a lower pain due to subjective improvement in the functionality at a long term. Although the procedures were effective with all implant designs the reliability of changes in the parameters was more evident with nonconstrained implants.
导言 小关节置换是治疗手部指骨关节变形性骨关节炎和外伤的有效方法,可恢复手部运动功能。本研究旨在评估使用不同植入物进行手部近端指间关节置换术的长期效果,并确定其优势。通过术前和术后对关节活动范围的测量、疼痛评估、X光片以及使用手臂、肩部和手部残疾(DASH)问卷进行的结果评估,在6个月和随访阶段对结果进行了评估。疼痛综合征有所减轻。X光片显示,约束假体组中有10例出现无菌性不稳定。DASH评估显示,患者对治疗的主观满意度很高。 讨论 我们没有找到报告使用SBI D.G.T.植入系统进行PIP关节置换术的论文。一项关于 RM Finger PIP 关节置换术的回顾性研究表明,虽然并发症发生率较高,但该手术恢复了关节稳定性,改善了关节活动度,且疼痛较轻。我们的记录显示,该植入模型未出现并发症。一些作者不推荐将 RM Finger(Mathys)植入体用于 PIP 关节置换术。使用 MOJE kermik-implantate 对手部小关节进行关节置换术后,82% 的患者长期疗效令人满意。虽然所有植入物设计的手术都很有效,但参数变化的可靠性在非受限植入物中更为明显。
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引用次数: 0
Non-obvious and obvious signs of the thoracic spine pathology: a clinical study 胸椎病变的非明显和明显征兆:一项临床研究
Q3 Medicine Pub Date : 2024-04-19 DOI: 10.18019/1028-4427-2024-30-2-200-209
M. R. Jasim, M. A. M. Saeed
Background The thoracic spine pathology can lead to severe disability and discomfort.This study aims to identify determinant characteristics in patients with thoracic spine pathologies who present with non-regional complaints such as lumbar/cervical pain and others.Methods A prospective observational descriptive study was conducted at Basrah Teaching Hospital from March 2020 to December 2021, enrolling 114 patients categorized into two groups. Group A included patients with thoracic spine pathology and thoracic pain, while Group B consisted of patients with thoracic spine pathology and non-local symptoms (such as lower lumbar pain, pain in extremities, etc.). Comprehensive clinical evaluations were performed using a specially designed questionnaire.Results The majority of patients were in the 60-79 age group, with females comprising 55 % in Group A and 60 % in Group B. Smoking was observed in 28.98 % of Group A and 26.66 % of Group B. Symptomatic patients with solitary back pain commonly exhibited dorsal root compression symptoms (49.27 %), lower limb weakness (18.84 %), and sphincter dysfunction (7.24 %). Patients with thoracic plus lower and/or neck pain frequently reported paraesthesia (42.22 %) and cervical root symptoms (48.38 %). Kyphotic deformity was present in 20.28 % of Group A and 11.11 % of Group B, while tenderness was observed in 23.18 % of Group A and 13.33 % of Group B. Plain radiograph changes, including disk space narrowing (44.44 %), subchondral sclerosis (29.63 %), curve alterations (29.63 %), and facet arthropathy (25.9 %), were more prevalent in those with symptomatic thoracic back pain (Group A).Conclusion Non-local symptoms in thoracic spine pathologies are common, with complicated and multi-site low back pain being more prevalent than isolated back or thoracic pain. Elderly individuals, females, obesity, and comorbidities appear to be predictive risk factors for low back pain development. Paraesthesia emerges as the most common neurological manifestation, while kyphosis and scoliosis are primary presentations of thoracic pathologies. Multi-modalities of imaging, including plain radiographs, MRI, CT scan, and DEXA scan, can aid in detecting back pathologies. The mainstay of managing symptomatic thoracic pathologies is surgical intervention.
方法 2020 年 3 月至 2021 年 12 月在巴士拉教学医院开展了一项前瞻性观察描述性研究,共纳入 114 名患者,分为两组。A 组包括胸椎病变和胸痛患者,B 组包括胸椎病变和非局部症状(如下腰痛、四肢疼痛等)患者。大多数患者年龄在 60-79 岁之间,女性在 A 组和 B 组中分别占 55% 和 60%。A 组和 B 组中分别有 28.98% 和 26.66% 的患者吸烟。胸痛加下肢和/或颈部疼痛的患者通常会出现麻痹(42.22%)和颈根症状(48.38%)。A 组和 B 组分别有 20.28% 和 11.11% 的患者出现駝背畸形,而 A 组和 B 组分别有 23.18% 和 13.33% 的患者出现压痛。平片变化包括椎间盘间隙变窄(44.44%)、软骨下硬化(29.63%)、曲线改变(29.结论 胸椎病变中的非局部症状很常见,复杂和多部位腰痛比孤立的腰痛或胸痛更常见。老年人、女性、肥胖和合并症似乎是导致腰背痛的风险因素。麻痹是最常见的神经系统表现,而脊柱侧弯和脊柱侧凸则是胸廓病变的主要表现。包括普通X光片、核磁共振成像、CT扫描和DEXA扫描在内的多种成像方式都有助于检测背部病变。治疗有症状的胸部病变的主要方法是手术干预。
{"title":"Non-obvious and obvious signs of the thoracic spine pathology: a clinical study","authors":"M. R. Jasim, M. A. M. Saeed","doi":"10.18019/1028-4427-2024-30-2-200-209","DOIUrl":"https://doi.org/10.18019/1028-4427-2024-30-2-200-209","url":null,"abstract":"Background The thoracic spine pathology can lead to severe disability and discomfort.This study aims to identify determinant characteristics in patients with thoracic spine pathologies who present with non-regional complaints such as lumbar/cervical pain and others.Methods A prospective observational descriptive study was conducted at Basrah Teaching Hospital from March 2020 to December 2021, enrolling 114 patients categorized into two groups. Group A included patients with thoracic spine pathology and thoracic pain, while Group B consisted of patients with thoracic spine pathology and non-local symptoms (such as lower lumbar pain, pain in extremities, etc.). Comprehensive clinical evaluations were performed using a specially designed questionnaire.Results The majority of patients were in the 60-79 age group, with females comprising 55 % in Group A and 60 % in Group B. Smoking was observed in 28.98 % of Group A and 26.66 % of Group B. Symptomatic patients with solitary back pain commonly exhibited dorsal root compression symptoms (49.27 %), lower limb weakness (18.84 %), and sphincter dysfunction (7.24 %). Patients with thoracic plus lower and/or neck pain frequently reported paraesthesia (42.22 %) and cervical root symptoms (48.38 %). Kyphotic deformity was present in 20.28 % of Group A and 11.11 % of Group B, while tenderness was observed in 23.18 % of Group A and 13.33 % of Group B. Plain radiograph changes, including disk space narrowing (44.44 %), subchondral sclerosis (29.63 %), curve alterations (29.63 %), and facet arthropathy (25.9 %), were more prevalent in those with symptomatic thoracic back pain (Group A).Conclusion Non-local symptoms in thoracic spine pathologies are common, with complicated and multi-site low back pain being more prevalent than isolated back or thoracic pain. Elderly individuals, females, obesity, and comorbidities appear to be predictive risk factors for low back pain development. Paraesthesia emerges as the most common neurological manifestation, while kyphosis and scoliosis are primary presentations of thoracic pathologies. Multi-modalities of imaging, including plain radiographs, MRI, CT scan, and DEXA scan, can aid in detecting back pathologies. The mainstay of managing symptomatic thoracic pathologies is surgical intervention.","PeriodicalId":37426,"journal":{"name":"Genij Ortopedii","volume":" 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140684828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bilateral reconstruction of palmar soft tissues defects of the hands after thermal injury 热损伤后手掌软组织缺损的双侧重建
Q3 Medicine Pub Date : 2024-02-21 DOI: 10.18019/1028-4427-2024-30-1-107-113
E. M. Biktasheva, B. Minasov, M. M. Valeev, R. Yakupov, T. Minasov, T. Mavlyutov
Introduction Thermal injury to the palmar surface of the hand is usually complicated by flexion desmogenic contracture of the finger joints. This condition is more complicated with significant wound areas and depths of soft tissue destruction. Conventional surgical methods and soft tissue reconstructions may fail to provide full restoration of the hand function.The objective was to present the optimal treatment strategy for patients with scar flexion contractures of the fingers after thermal injury to the palmar surface of both hands using a pediatric case report.Material and methods A child aged 2 years and 4 months underwent surgical treatment to include excision of scars, skin grafting of both hands with a vascularized fasciocutaneous flap raised with the radial artery.Result The patient could regain all types of hand grip on both sides 12 years after surgical treatment. Both hands were aesthetically acceptable.Discussion Treatment of patients with thermal injury and substantial soft tissue damage is a complex disease process. Conservative treatment and surgical procedures using non-vascularized skin flaps are normally used for the condition. These approaches are associated with cicatricial and arthrogenic flexion contracture of the finger joints. The radical treatment includes thorough wound debridement and early flap coverage and wound closure using a flap with an axial-pattern blood supply, free flaps and reverse-flow flaps. The surgical approach helps to avoid flexion contracture of the fingers initiating early restoration of professional, social stereotypes and stereotypes in everyday life.Conclusion The clinical observation has shown the possibility of one-stage organ-preserving surgical treatment using flaps with an axial blood supply.
引言 手掌表面的热损伤通常会并发手指关节的屈曲脱膜挛缩。这种情况在伤口面积大、软组织破坏深度深的情况下更为复杂。材料和方法 一名 2 岁 4 个月的患儿接受了手术治疗,包括切除疤痕,用桡动脉血管化筋膜皮瓣移植双手皮肤。讨论 热损伤和严重软组织损伤患者的治疗是一个复杂的疾病过程。通常采用保守治疗和使用无血管皮瓣的手术治疗方法。这些方法都与手指关节的卡他性和关节源性屈曲挛缩有关。根治方法包括彻底清创、早期皮瓣覆盖以及使用轴向供血皮瓣、游离皮瓣和反向流动皮瓣关闭伤口。该手术方法有助于避免手指屈曲挛缩,及早恢复日常生活中的职业、社交定型和定型。
{"title":"Bilateral reconstruction of palmar soft tissues defects of the hands after thermal injury","authors":"E. M. Biktasheva, B. Minasov, M. M. Valeev, R. Yakupov, T. Minasov, T. Mavlyutov","doi":"10.18019/1028-4427-2024-30-1-107-113","DOIUrl":"https://doi.org/10.18019/1028-4427-2024-30-1-107-113","url":null,"abstract":"Introduction Thermal injury to the palmar surface of the hand is usually complicated by flexion desmogenic contracture of the finger joints. This condition is more complicated with significant wound areas and depths of soft tissue destruction. Conventional surgical methods and soft tissue reconstructions may fail to provide full restoration of the hand function.The objective was to present the optimal treatment strategy for patients with scar flexion contractures of the fingers after thermal injury to the palmar surface of both hands using a pediatric case report.Material and methods A child aged 2 years and 4 months underwent surgical treatment to include excision of scars, skin grafting of both hands with a vascularized fasciocutaneous flap raised with the radial artery.Result The patient could regain all types of hand grip on both sides 12 years after surgical treatment. Both hands were aesthetically acceptable.Discussion Treatment of patients with thermal injury and substantial soft tissue damage is a complex disease process. Conservative treatment and surgical procedures using non-vascularized skin flaps are normally used for the condition. These approaches are associated with cicatricial and arthrogenic flexion contracture of the finger joints. The radical treatment includes thorough wound debridement and early flap coverage and wound closure using a flap with an axial-pattern blood supply, free flaps and reverse-flow flaps. The surgical approach helps to avoid flexion contracture of the fingers initiating early restoration of professional, social stereotypes and stereotypes in everyday life.Conclusion The clinical observation has shown the possibility of one-stage organ-preserving surgical treatment using flaps with an axial blood supply.","PeriodicalId":37426,"journal":{"name":"Genij Ortopedii","volume":"17 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140442604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intramedullary osteosynthesis for ankle fractures and distal tibiofibular syndesmotic disruption 踝关节骨折和胫腓骨远端联合韧带断裂的髓内骨合成术
Q3 Medicine Pub Date : 2024-02-21 DOI: 10.18019/1028-4427-2024-30-1-142-152
F. A. Gafurov, I. Y. Khodzhanov, D. Mansurov, Sh. N. Eranov
Introduction The optimal surgical approach for malleolar fractures and distal tibiofibular syndesmotic (DTFS) disruption remains controversial. There is no uniform treatment protocol for this type of injury.The objective was to review modern surgical treatments of the pathology and determine the optimal option.Material and methods Articles of French, English, Uzbek, Kazakh, German, Danish, Japanese and Chinese authors were retrospectively reviewed. An internet search of MedLine; PubMed; Scopus; Web of Science, CINAHL, the Cochrane Central Register of Controlled Trials databases was performed.Results Comparative studies of dynamic fixation and static fixation of the DTFS showed advantages of the dynamic methods enabling precise, anatomical syndesmotic fixation and faster healing. Dynamic fixation methods would require no implant removal, while syndesmotic screw woul be taken off to reduce compression in the ankle joint and minimize a risk of malreduction facilitating mobility of the ankle joint. Dynamic methods are associated with greater stability and less complication rate. However, static methods have the advantages of being more accessible and less expensive, which can be an important factor choosing a treatment method. Static methods are a wide application and can be used in a wide range of clinical cases. Long-term results show no statistically significant differences between dynamic fixation and static fixation.Discussion Literature review indicates the dynamic method with suture-button, a combined method and titanium cable isotonic annular fixation system as the preferred technique for surgical stabilization of distal syndesmosis associated with ankle fractures with a lower risk of postoperative complications and the possibility of short-term rehabilitation.Conclusion The choice between dynamic and static methods of distal syndesmosis fixation depends on many factors, including the complexity of the injury, the availability and cost of implants and the experience of the surgeon.
引言 踝骨骨折和胫腓骨远端联合(DTFS)断裂的最佳手术方法仍存在争议。材料和方法 回顾性研究了法国、英国、乌兹别克斯坦、哈萨克斯坦、德国、丹麦、日本和中国作者的文章。对 MedLine、PubMed、Scopus、Web of Science、CINAHL 和 Cochrane Central Register of Controlled Trials 等数据库进行了网络检索。动态固定方法不需要移除植入物,而巩膜螺钉则需要取下,以减少对踝关节的压迫,并最大限度地降低畸形风险,促进踝关节的活动度。动态方法具有更高的稳定性和更低的并发症发生率。然而,静态方法具有更容易获得、费用更低的优点,这可能是选择治疗方法的一个重要因素。静态方法应用广泛,可用于多种临床病例。讨论 文献综述表明,缝合-钮扣动态法、联合法和钛索等张环形固定系统是与踝关节骨折相关的远端巩膜手术稳定的首选技术,术后并发症风险较低,且可进行短期康复。
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引用次数: 0
Mechanisms of musculoskeletal consequences of COVID-19 COVID-19 对肌肉骨骼的影响机制
Q3 Medicine Pub Date : 2024-02-21 DOI: 10.18019/1028-4427-2024-30-1-153-162
N. N. Grigoryeva, G. Airapetov
Introduction A coronavirus, SARS-CoV-2, called COVID-19 by the WHO has caused a pandemic of respiratory illness killed more than 6 million people. The severe infection has a significant negative impact on the entire musculoskeletal system.The objective was to summarize literature data on the mechanisms of the condition and identify musculoskeletal symptoms of COVID-19.Material and methods An internet search of PubMed, MedLine and eLIBRARY library databases using the search terms: COVID-19, aseptic osteonecrosis, post-COVID-19 syndrome, arthropathy, musculoskeletal system, spondylitis, osteoporosis was performed.Results and discussion Musculoskeletal symptoms of COVID-19 are reported in 31-59% of cases. Mechanisms of musculoskeletal involvement of coronavirus infection include cytotoxic effect of the virus on osteogenesis cells, vascular inflammation and coagulopathy, “cytokine storm”, side effects of drug therapy and hypoxia. According to an etiological factor, musculoskeletal manifestations of SARS-CoV-2 include autoimmune (reactive arthritis, sacroiliitis, ankylosing spondylitis, axial spondyloarthritis, psoriatic arthritis) conditions caused by impaired circulation of bone tissue (aseptic osteonecrosis), infectious (septic arthritis, spondylitis, spondylodiscitis) and metabolic (osteopenia, osteoporosis) conditions.Conclusion It has been established that COVID-19 infection has a negative impact on the musculoskeletal, endocrine and immune systems increasing the risk of degenerative diseases of the musculoskeletal system and infectious complications in orthopaedic patients early post surgery.
引言 一种冠状病毒 SARS-CoV-2(世界卫生组织称之为 COVID-19)引起了一场呼吸道疾病大流行,造成 600 多万人死亡。材料与方法 使用检索词对 PubMed、MedLine 和 eLIBRARY 图书馆数据库进行互联网检索:COVID-19、无菌性骨坏死、COVID-19后综合征、关节病、肌肉骨骼系统、脊柱炎、骨质疏松症。结果与讨论 31-59%的病例报告了COVID-19的肌肉骨骼症状。冠状病毒感染累及肌肉骨骼的机制包括病毒对成骨细胞的细胞毒性作用、血管炎症和凝血病、"细胞因子风暴"、药物治疗的副作用和缺氧。根据病因,SARS-CoV-2 的肌肉骨骼表现包括由骨组织循环受损(无菌性骨坏死)、感染(化脓性关节炎、脊柱炎、脊柱盘炎)和代谢(骨质疏松、骨质疏松症)引起的自身免疫性疾病(反应性关节炎、骶髂关节炎、强直性脊柱炎、轴性脊柱关节炎、银屑病关节炎)。结论 COVID-19 感染对肌肉骨骼、内分泌和免疫系统有负面影响,增加了骨科患者术后早期出现肌肉骨骼退行性疾病和感染并发症的风险。
{"title":"Mechanisms of musculoskeletal consequences of COVID-19","authors":"N. N. Grigoryeva, G. Airapetov","doi":"10.18019/1028-4427-2024-30-1-153-162","DOIUrl":"https://doi.org/10.18019/1028-4427-2024-30-1-153-162","url":null,"abstract":"Introduction A coronavirus, SARS-CoV-2, called COVID-19 by the WHO has caused a pandemic of respiratory illness killed more than 6 million people. The severe infection has a significant negative impact on the entire musculoskeletal system.The objective was to summarize literature data on the mechanisms of the condition and identify musculoskeletal symptoms of COVID-19.Material and methods An internet search of PubMed, MedLine and eLIBRARY library databases using the search terms: COVID-19, aseptic osteonecrosis, post-COVID-19 syndrome, arthropathy, musculoskeletal system, spondylitis, osteoporosis was performed.Results and discussion Musculoskeletal symptoms of COVID-19 are reported in 31-59% of cases. Mechanisms of musculoskeletal involvement of coronavirus infection include cytotoxic effect of the virus on osteogenesis cells, vascular inflammation and coagulopathy, “cytokine storm”, side effects of drug therapy and hypoxia. According to an etiological factor, musculoskeletal manifestations of SARS-CoV-2 include autoimmune (reactive arthritis, sacroiliitis, ankylosing spondylitis, axial spondyloarthritis, psoriatic arthritis) conditions caused by impaired circulation of bone tissue (aseptic osteonecrosis), infectious (septic arthritis, spondylitis, spondylodiscitis) and metabolic (osteopenia, osteoporosis) conditions.Conclusion It has been established that COVID-19 infection has a negative impact on the musculoskeletal, endocrine and immune systems increasing the risk of degenerative diseases of the musculoskeletal system and infectious complications in orthopaedic patients early post surgery.","PeriodicalId":37426,"journal":{"name":"Genij Ortopedii","volume":"52 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140444962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mesenchymal stem cells and exosomes in bone defects treatment 治疗骨缺损的间充质干细胞和外泌体
Q3 Medicine Pub Date : 2024-02-21 DOI: 10.18019/1028-4427-2024-30-1-124-133
A. I. Greben, P. Eremin, E. Y. Kostromina, P. A. Markov, I. Gilmutdinova
Introduction Bone defect management is a critical stage of treatment and rehabilitation that still remains a challenging problem for traumatologists and orthopaedists. The need for tissue engineering techniques is due to limited abilities of the human body to correct bone tissue autoregeneration, especially in comorbid and elderly patients with osteoporosis. Bone autografts is a gold standard in those cases but is associated with certain restrictions. Regenerative medicine and stem cell biology development opened up capabilities to employ new methods for enhancement of bone tissue repair. A special interest of researchers is focused on mesenchymal stem cells and extracellular vesicles for bone tissue regeneration optimization.Purpose of this review was to show mesenchymal stem cells and exosomes effeciency in bone defect treatment.Materials and methods Open electronic databases of scientific literature, PubMed and e-Library, were used. The literature data search was carried out using the keywords: regenerative medicine, bone defects, exosomes, mesenchymal stem cells.Results and discussion The review presents current ideas about mesenchymal stem cells, their microenvironment and exosomes influence on bone tissue repair. Clinical need in effective bone regeneration is still high. Mesenchymal stem cells and acellular regenerative treatments have shown good results in bone defects repair and are perspective directions. Productive use of mesenchymal stem cells and exosomes in bone defects treatment requires further study of their mechanisms of action, the regenerative techniques efficacy and safety evaluation in preclinical and clinical studies.Conclusion The use of mesenchymal stem cells and cell-free regenerative approaches has demonstrated good results in the restoration of bone tissue defects and is a promising direction.
引言 骨缺损处理是治疗和康复的关键阶段,对于创伤学家和矫形学家来说,这仍然是一个具有挑战性的问题。之所以需要组织工程技术,是因为人体纠正骨组织自体再生的能力有限,尤其是合并症和老年骨质疏松症患者。在这些病例中,骨自体移植是一种黄金标准,但也有一定的限制。再生医学和干细胞生物学的发展为采用新方法增强骨组织修复能力提供了可能。研究人员特别关注间充质干细胞和细胞外囊泡对骨组织再生的优化作用。本综述旨在展示间充质干细胞和外泌体在骨缺损治疗中的功效。结果与讨论 该综述介绍了目前有关间充质干细胞、其微环境和外泌体对骨组织修复影响的观点。有效骨再生的临床需求仍然很高。间充质干细胞和细胞再生疗法在骨缺损修复方面取得了良好的效果,是未来的发展方向。间充质干细胞和外泌体在骨缺损治疗中的有效利用,需要在临床前和临床研究中进一步研究其作用机制、再生技术的有效性和安全性评估。
{"title":"Mesenchymal stem cells and exosomes in bone defects treatment","authors":"A. I. Greben, P. Eremin, E. Y. Kostromina, P. A. Markov, I. Gilmutdinova","doi":"10.18019/1028-4427-2024-30-1-124-133","DOIUrl":"https://doi.org/10.18019/1028-4427-2024-30-1-124-133","url":null,"abstract":"Introduction Bone defect management is a critical stage of treatment and rehabilitation that still remains a challenging problem for traumatologists and orthopaedists. The need for tissue engineering techniques is due to limited abilities of the human body to correct bone tissue autoregeneration, especially in comorbid and elderly patients with osteoporosis. Bone autografts is a gold standard in those cases but is associated with certain restrictions. Regenerative medicine and stem cell biology development opened up capabilities to employ new methods for enhancement of bone tissue repair. A special interest of researchers is focused on mesenchymal stem cells and extracellular vesicles for bone tissue regeneration optimization.Purpose of this review was to show mesenchymal stem cells and exosomes effeciency in bone defect treatment.Materials and methods Open electronic databases of scientific literature, PubMed and e-Library, were used. The literature data search was carried out using the keywords: regenerative medicine, bone defects, exosomes, mesenchymal stem cells.Results and discussion The review presents current ideas about mesenchymal stem cells, their microenvironment and exosomes influence on bone tissue repair. Clinical need in effective bone regeneration is still high. Mesenchymal stem cells and acellular regenerative treatments have shown good results in bone defects repair and are perspective directions. Productive use of mesenchymal stem cells and exosomes in bone defects treatment requires further study of their mechanisms of action, the regenerative techniques efficacy and safety evaluation in preclinical and clinical studies.Conclusion The use of mesenchymal stem cells and cell-free regenerative approaches has demonstrated good results in the restoration of bone tissue defects and is a promising direction.","PeriodicalId":37426,"journal":{"name":"Genij Ortopedii","volume":"6 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140445633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current state and perspectives on the use of zirconium ceramic implants in traumatology and orthopaedics 锆陶瓷植入物在创伤和矫形外科中的应用现状和前景
Q3 Medicine Pub Date : 2024-02-21 DOI: 10.18019/1028-4427-2024-30-1-114-123
E. A. Volokitina, I. Antropova, K. A. Timofeev, R. A. Trufanenko
Background Ceramic materials are currently in wide demand in various fields of medicine. Zirconium ceramics demonstrate exceptional mechanical properties and biocompatibility and do not cause cytotoxic effects or allergic reactions in surrounding tissues.The objective was to present an analysis of current literature data on the use of zirconium ceramics as a bone replacement material in traumatology and orthopaedics.Materials and methods The search for publications was conducted using the databases of Scopus, PubMed and the electronic scientific library eLIBRARY in the Russian and English languages using the keywords: bioceramics, bone, bone defect, zirconate, zirconium ceramics, bone tissue engineering, implant, scaffold, augment, biointegration, bioactivity. Depth of search for scientific papers was from 2000 to 2023.Results and discussion Zirconium dioxide is the main ceramic bioinert material. The study presents the characteristics of ZrO2 as a bone replacement material and its comparison with titanium implants. Data are presented on various strategies for improving zirconium bioceramics: improving the surface of the material by physical and chemical methods, obtaining volumetric porosity, including using additive technologies, creating composite materials, and developing bioactive coatings. New methods of creating zirconium ceramics compatible with living tissues containing bioactive ions that promote both osseointegration and bone tissue regeneration have been actively studied.Conclusions Zirconium dioxide ceramics appear to be a promising alternative to titanium implants in terms of mechanical strength, biological functionality, chemical stability, osseointegration, and antibacterial properties. Future experimental and clinical studies will further improve zirconium ceramics.
背景 陶瓷材料目前在医学的各个领域都有着广泛的需求。锆陶瓷具有优异的机械性能和生物相容性,不会对周围组织产生细胞毒性作用或过敏反应。本研究旨在分析目前有关锆陶瓷作为骨替代材料用于创伤学和矫形外科的文献资料。材料和方法 使用 Scopus、PubMed 和电子科学图书馆 eLIBRARY 等数据库以俄语和英语搜索出版物,关键词为:生物陶瓷、骨、骨缺损、锆酸盐、锆陶瓷、骨组织工程、植入物、支架、增量、生物整合、生物活性。科学论文的检索深度为 2000 年至 2023 年。结果与讨论 二氧化锆是主要的陶瓷生物惰性材料。本研究介绍了二氧化锆作为骨替代材料的特性及其与钛植入物的比较。研究数据介绍了改进锆生物陶瓷的各种策略:通过物理和化学方法改进材料表面、获得体积孔隙率(包括使用添加剂技术)、创建复合材料以及开发生物活性涂层。结论 二氧化锆陶瓷在机械强度、生物功能、化学稳定性、骨结合和抗菌性能等方面似乎有望成为钛植入物的替代品。未来的实验和临床研究将进一步提高锆陶瓷的性能。
{"title":"Current state and perspectives on the use of zirconium ceramic implants in traumatology and orthopaedics","authors":"E. A. Volokitina, I. Antropova, K. A. Timofeev, R. A. Trufanenko","doi":"10.18019/1028-4427-2024-30-1-114-123","DOIUrl":"https://doi.org/10.18019/1028-4427-2024-30-1-114-123","url":null,"abstract":"Background Ceramic materials are currently in wide demand in various fields of medicine. Zirconium ceramics demonstrate exceptional mechanical properties and biocompatibility and do not cause cytotoxic effects or allergic reactions in surrounding tissues.The objective was to present an analysis of current literature data on the use of zirconium ceramics as a bone replacement material in traumatology and orthopaedics.Materials and methods The search for publications was conducted using the databases of Scopus, PubMed and the electronic scientific library eLIBRARY in the Russian and English languages using the keywords: bioceramics, bone, bone defect, zirconate, zirconium ceramics, bone tissue engineering, implant, scaffold, augment, biointegration, bioactivity. Depth of search for scientific papers was from 2000 to 2023.Results and discussion Zirconium dioxide is the main ceramic bioinert material. The study presents the characteristics of ZrO2 as a bone replacement material and its comparison with titanium implants. Data are presented on various strategies for improving zirconium bioceramics: improving the surface of the material by physical and chemical methods, obtaining volumetric porosity, including using additive technologies, creating composite materials, and developing bioactive coatings. New methods of creating zirconium ceramics compatible with living tissues containing bioactive ions that promote both osseointegration and bone tissue regeneration have been actively studied.Conclusions Zirconium dioxide ceramics appear to be a promising alternative to titanium implants in terms of mechanical strength, biological functionality, chemical stability, osseointegration, and antibacterial properties. Future experimental and clinical studies will further improve zirconium ceramics.","PeriodicalId":37426,"journal":{"name":"Genij Ortopedii","volume":"11 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140442093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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