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Comparison of orthopaedic reconstruction of diabetic Charcot foot Eichenholtz stages 1-2 and conservative treatment 糖尿病Charcot足Eichenholtz 1-2期骨科重建与保守治疗的比较
Q3 Medicine Pub Date : 2023-06-01 DOI: 10.18019/1028-4427-2023-29-3-244-252
S. Osnach, V. Protsko, V. Obolensky, V. B. Bregovsky, A. Demina, S. Tamoev, E.Yu. Komelagina, N.I. Sabancheeva, M. Imankulov
The objective was to evaluate the efficacy and safety of closed transosseous osteosynthesis in the treatment of patients with diabetic Charcot neuroosteoarthropathy at the acute radiographically positive stage (Eichenholtz 1-2) with hindfoot and midfoot deformity and immobilization using Total Contact Cast. Material and methods Eight patients of the treatment group underwent closed deformity correction and Ilizarov external fixation. The frame was removed with radiographic signs of consolidation and conservative methods of fixation and off-loading employed. The control group consisted of 11 patients who received outpatient conservative treatment with Total Contact Cast combined with crutches. Results The treatment length of surgical patients prior to the use of orthopaedic shoes was shorter than that of patients treated conservatively. Foot ulcers seen in the conservative group during the observation period were not detected in the surgical cases and were associated with the lack of deformity correction. Discussion The advantage of operative reconstruction includes more stable foot and lower risk of ulcers. Reduced rehabilitation period improves the patient's quality of life. Complications that developed in the treatment group were resolved and had no effect on the outcome. Conclusion Closed deformity correction using transosseous osteosynthesis can be an option for patients with diabetic Charcot neuroosteoarthropathy at the acute radiographically positive stage as compared to the conservative treatment.
目的是评估闭合性经骨骨内固定术治疗急性放射学阳性期(Eichenholtz 1-2)伴有后足和中足畸形并使用全接触石膏固定的糖尿病Charcot神经骨关节病患者的疗效和安全性。材料与方法治疗组8例患者行闭式畸形矫正及Ilizarov外固定。采用保守的固定和卸载方法拆除框架,影像学显示有巩固迹象。对照组11例患者接受门诊全接触石膏联合拐杖保守治疗。结果手术前使用矫形鞋的患者治疗时间短于保守治疗的患者。保守组观察期间的足部溃疡未在手术病例中发现,且与缺乏畸形矫正有关。手术重建的优点包括更稳定的足部和更低的溃疡风险。缩短康复期可提高患者的生活质量。治疗组出现的并发症均得到解决,对结果无影响。结论与保守治疗相比,经骨内固定术治疗糖尿病Charcot神经骨关节病可作为一种治疗急性影像学阳性期畸形的方法。
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引用次数: 0
Digital modeling of critical conditions after metacarpophalangeal joint replacement 掌指关节置换术后危急情况的数字模拟
Q3 Medicine Pub Date : 2023-04-01 DOI: 10.18019/1028-4427-2023-29-2-148-154
A. Nikolaenko, V.V. vanov, S. Doroganov, A. Bukaty, D.O. Zgirsky, P.Yu. Isaykin
Introduction The current status of small joint arthroplasty, the metacarpophalangeal joint replacement, in particular, dictates the need for development and research of new implant designs and materials for their manufacture. The vector of development of anatomically adapted implants has become established, and full preclinical study is required to obtain the best functional results from the use of new medical devices. The objective was to analyze digital models of critical conditions of metacarpophalangeal joint replacement using mechanical and clinical data. Material and methods A two‑component all-ceramic, anatomically adapted endoprosthesis of the metacarpophalangeal joint was developed between 2017 and 2021. A digital model of the metacarpophalangeal joint endoprosthesis was constructed using 3D modeling technology. Critical conditions of the digital model imitating the main stereotypes of movements were explored with the finite element method; objective technical results obtained and interpreted in a clinical language. Results Loads over 20 kg should be avoided with movements up to 60° in the early postoperative period. The load must not exceed 10 kg for motion ranging between 60° and 90°. The endoprosthesis allowed for a functional range of motion of 30-60° after MCP joint replacement without significant risks of complications. Discussion The study has demonstrated the importance of objectifying clinical results to minimize the risk of complications in a clinical scenario. Conclusion The technology based on a digital model of the metacarpophalangeal joint constructed to calculate critical conditions using the Ansys software facilitated prediction of most common complications of MCP arthroplasty and preceded further multicentric clinical trials.
小关节置换术的现状,特别是掌指关节置换术,要求开发和研究新的植入物设计和制造材料。适应解剖结构的植入物的发展载体已经建立,需要进行充分的临床前研究,以从使用新的医疗器械中获得最佳的功能结果。目的是利用力学和临床数据分析掌指关节置换术的关键条件的数字模型。材料和方法2017年至2021年间开发了一种双组份全陶瓷、解剖适应的掌指关节内假体。采用三维建模技术建立了掌指关节假体的数字模型。利用有限元法对数字模型模拟主要运动模式的临界条件进行了探索;用临床语言获得客观的技术结果并加以解释。结果术后早期应避免负重超过20 kg,避免活动60°。在60°至90°的运动范围内,负载不得超过10 kg。内假体允许MCP关节置换术后30-60°的功能活动范围,没有明显的并发症风险。该研究证明了客观的临床结果对于减少临床并发症风险的重要性。结论基于Ansys软件构建掌指关节数字模型计算临界状态的技术有助于预测MCP关节置换术中最常见的并发症,为进一步的多中心临床试验奠定基础。
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引用次数: 0
Models for purulent septic inflammation of the tibia in rats to assess the effect of bioresorbable materials with antimicrobial drugs 建立大鼠胫骨化脓性脓毒性炎症模型,评价生物可吸收材料与抗菌药物的作用
Q3 Medicine Pub Date : 2023-04-01 DOI: 10.18019/1028-4427-2023-29-2-190-203
D. Smolentsev, Yu. S. Lukina, L. Bionyshev-Abramov, N. Serezhnikova, M. G. Vasiliev, A. Senyagin, T. Pkhakadze
Introduction A brief review of modeling purulent septic inflammation in rats, including with the help of an active bacterial agent, and methods for diagnosing inflammation are given. The aim of the study was to demonstrate the results of the development of an effective experimental model of purulent septic inflammation of the tibia in rats using minimally invasive methods for diagnosing infection in vivo. Materials and methods Various models of purulent septic inflammation were studied in four groups of small laboratory animals, when using the inoculation of Staphylococcus aureus. Methods for assessing purulent-septic inflammation that are not destructible by the object have been worked out: microbiological, tomographic, morphological. Results The results of the study indicate the possibility of creating experimental purulent-septic inflammation in rats by 14-60 days using S. aureus inoculation, which is a severe, rapidly progressive purulent infection that leads to extensive destruction of the bone with the formation of sequesters. Discussion To guarantee the formation of a purulent-inflammatory process of bone tissue in a shorter period of observation, a quantitatively controlled invasion of an active bacterial agent is necessary. A sclerosing agent and formation of a fistulous tract are not essential in creating inflammation. Conclusion The results of the development of experimental models for the creation of purulent-septic inflammation using minimally invasive in vivo diagnostic methods are demonstrated, which will allow an adequate assessment of the degree of infection before treatment.
简要综述了大鼠化脓性脓毒性炎症模型的研究进展,包括利用活性菌剂的方法,以及炎症的诊断方法。该研究的目的是证明利用微创方法诊断大鼠胫骨脓毒性炎症的有效实验模型的发展结果。材料与方法采用金黄色葡萄球菌接种四组小实验动物,研究各种化脓性脓毒性炎症模型。评估化脓性败血性炎症的方法,不破坏的对象已经制定:微生物,层析成像,形态学。结果本研究结果表明,接种金黄色葡萄球菌可在大鼠体内产生14-60天的实验性化脓性脓毒性炎症,这是一种严重的、快速进展的化脓性感染,可导致骨的广泛破坏并形成隔离物。为了保证在较短的观察时间内形成骨组织的化脓性炎症过程,有必要定量控制活性细菌的入侵。硬化剂和瘘管的形成并不是引起炎症的必要条件。结论利用微创体内诊断方法建立化脓性脓毒性炎症实验模型的结果得到证实,这将允许在治疗前充分评估感染程度。
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引用次数: 0
Emergency histological examination in diagnosis of periprosthetic joint infection in revision total knee arthroplasty 急诊组织学检查在全膝关节置换术中诊断假体周围关节感染的价值
Q3 Medicine Pub Date : 2023-04-01 DOI: 10.18019/1028-4427-2023-29-2-180-189
A. N. Panteleev, S. Bozhkova, R. Tikhilov, A. Kazemirsky, L. O. Anisimova, S.A. Guzyukina, P. Preobrazhensky, M. P. Zinoviev, A. V. Ovsyankin, V. B. Nakopiya
Introduction Diagnostic algorithms are used for detection of periprosthetic joint infection (PJI) including sampling for histological evaluation (HE). The purpose was to assess the diagnostic significance of emergency HE of fresh-frozen intraoperative biomaterial as part of preoperative PJI screening of patients undergoing revision total knee arthroplasty (RTKA). Material and methods The prospective study included 83 patients who were admitted to two trauma and orthopaedic centers for RTKA. The European Bone and Joint Infection Society 2021 (EBJIS21) algorithm was used to detect PJI of the knee joint. The diagnostic value of screening PJI with/without regard to the results of an emergency HE was compared with the results of a microbiological study (MBI) of all types of biomaterials obtained from each patient. Subanalysis was additionally performed in patients with aseptic instability and antimicrobial spacer. Results Pathomorphological examination of freshly frozen and paraffin-embedded tissues showed the difference of 7.2 %, which did not significantly affect the interpretation of the results (p > 0.05). Diagnostically significant pathogens were identified in 83.3 % of cases with PJI confirmed by emergency HE (p < 0.001). A positive emergency HE result increased the chances of isolating diagnostically significant organisms by 34 times (95 % confidence interval (CI): 4.721 – 244.859) as compared with negative HE cases. The proportion of detected cases with emergency HE included in the screening increased from 2.4 to 8.4 %. The inclusion of emergency HE in the screening improved the diagnostic value both in the general cohort of patients and in the subanalysis of comparison groups due to a two-fold increase in sensitivity. Conclusion Relevance of the emergency HE results and the PJI criteria should be considered as a significant prognostic factor for an infectious process, however, this technique should be used only in a complex algorithm for PJI detection. Poor outcomes in 18.2 % of cases of probable PJI necessitated a change in the approach to managing this cohort of patients.
诊断算法用于检测假体周围关节感染(PJI),包括取样进行组织学评估(HE)。目的是评估新鲜冷冻术中生物材料的急诊HE作为翻修全膝关节置换术(RTKA)患者术前PJI筛查的一部分的诊断意义。材料与方法本前瞻性研究包括83例在两家创伤骨科中心接受RTKA治疗的患者。采用欧洲骨与关节感染学会2021 (EBJIS21)算法检测膝关节PJI。将考虑/不考虑紧急HE结果的PJI筛查的诊断价值与从每位患者获得的所有类型生物材料的微生物学研究(MBI)结果进行比较。此外,对无菌不稳定和抗菌间隔的患者进行了亚分析。结果新鲜冷冻组织与石蜡包埋组织病理形态学差异为7.2%,对结果的解释无显著影响(p > 0.05)。在83.3%经急诊HE确诊的PJI病例中发现了诊断意义重大的病原体(p < 0.001)。与HE阴性病例相比,紧急HE阳性结果可使分离出诊断意义重大的生物体的机会增加34倍(95%置信区间(CI): 4.721 - 244.859)。筛查中发现的急诊HE病例的比例从2.4%增加到8.4%。由于灵敏度提高了两倍,在筛查中纳入急诊HE提高了一般患者队列和对照组亚分析的诊断价值。结论急诊HE结果与PJI标准的相关性应被视为感染过程的重要预后因素,然而,该技术应仅用于复杂的PJI检测算法。18.2%可能的PJI病例预后不佳,需要改变对这组患者的治疗方法。
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引用次数: 0
Posttraumatic hemarthrosis in view of the inflammation theory 基于炎症理论的创伤后关节血肿
Q3 Medicine Pub Date : 2023-04-01 DOI: 10.18019/1028-4427-2023-29-2-211-224
O. V. Berdiugina, V. Chereshnev, K. A. Berdiugin
Introduction Post-traumatic hemarthrosis is identified as intra-articular hemorrhage accompanied by five classic signs of inflammation: hyperemia, hyperthermia, edema, pain and changes in the joint function. The objective of the study was to establish whether inflammation should be underestimated in post-traumatic hemarthrosis based on the analysis of the world scientific literature of recent years. Material and methods Internet search platform Web of Science (Clarivate Analytics, USA): databases Web of Science Core Collection (subscription access), Publons (open access), Medline (open access) were used to review scientific articles. Papers from the Scopus Elsevier database (Netherlands) were explored. The search depth was 15 years. Topics that did not receive coverage in the literature of this period were studied until the 1960s in some cases. More than 200 sources were identified on the subject. The literature published in the current year was analyzed covering 15.0 % of the materials, brought out in the last 5 years including the current year covering 56.3 %, in the last 10 years including the current year covering 73.8 %, in the last 15 years including the current year covering 81.3 %. Results and discussion The severity of injury and the accompanying inflammatory factors would characterize a rapid resolution or a more severe course of post-traumatic hemarthrosis during treatment. The combination of several variants of inflammation can lead to the development of complications including osteoarthritis in cases that show mechanisms of chronic systemic inflammation of low intensity being manifested at the time of injury; ankylosis of the joint resulting from chronic systemic inflammation of low intensity involving degenerative processes. Synovitis, as a complication of post-traumatic hemarthrosis, should be differentiated with signs of low-grade inflammation, chronic course of classical inflammation and presystemic inflammation (purulent arthritis) in view of the inflammation theory. Conclusion The analysis of modern literature has shown the complexity and versatility of aspects of inflammation in posttraumatic hemarthrosis. The lack of emphasis on the assessment of the inflammatory response in rehabilitation of patients with post‑traumatic hemarthrosis can result in complications causing preconditions for the development of osteoarthritis, ankylosis, synovitis.
外伤性关节血肿是指关节内出血并伴有充血、高热、水肿、疼痛和关节功能改变等五种典型炎症症状。本研究的目的是在分析近年来世界科学文献的基础上,确定创伤后血关节炎症是否应该被低估。网络检索平台Web of Science (Clarivate Analytics, USA):使用Web of Science Core Collection(订阅获取)、Publons(开放获取)、Medline(开放获取)数据库对科学文章进行检索。从荷兰的Scopus Elsevier数据库中检索论文。搜索深度为15年。在某些情况下,直到20世纪60年代,在这一时期的文献中没有得到报道的主题才得到研究。在这个问题上,有超过200个消息来源被确认。本年度发表的文献被分析覆盖15.0%的材料,在最近5年包括本年度覆盖56.3%,在最近10年包括本年度覆盖73.8%,在最近15年包括本年度覆盖81.3%。结果和讨论创伤后关节血肿的严重程度和伴随的炎症因素在治疗过程中会迅速消退或更严重。在损伤时表现出低强度慢性全身性炎症机制的情况下,几种炎症变体的结合可导致并发症的发展,包括骨关节炎;关节强直由低强度的慢性全身性炎症引起,包括退行性过程。根据炎症理论,滑膜炎作为创伤后血关节的并发症,应与低度炎症、慢性经典炎症和全身前炎症(化脓性关节炎)相鉴别。结论对现代文献的分析显示创伤后血关节炎症的复杂性和多功能性。缺乏对创伤后血关节患者康复过程中炎症反应评估的重视,可导致并发症,为骨关节炎、强直、滑膜炎的发展提供先决条件。
{"title":"Posttraumatic hemarthrosis in view of the inflammation theory","authors":"O. V. Berdiugina, V. Chereshnev, K. A. Berdiugin","doi":"10.18019/1028-4427-2023-29-2-211-224","DOIUrl":"https://doi.org/10.18019/1028-4427-2023-29-2-211-224","url":null,"abstract":"Introduction Post-traumatic hemarthrosis is identified as intra-articular hemorrhage accompanied by five classic signs of inflammation: hyperemia, hyperthermia, edema, pain and changes in the joint function. The objective of the study was to establish whether inflammation should be underestimated in post-traumatic hemarthrosis based on the analysis of the world scientific literature of recent years. Material and methods Internet search platform Web of Science (Clarivate Analytics, USA): databases Web of Science Core Collection (subscription access), Publons (open access), Medline (open access) were used to review scientific articles. Papers from the Scopus Elsevier database (Netherlands) were explored. The search depth was 15 years. Topics that did not receive coverage in the literature of this period were studied until the 1960s in some cases. More than 200 sources were identified on the subject. The literature published in the current year was analyzed covering 15.0 % of the materials, brought out in the last 5 years including the current year covering 56.3 %, in the last 10 years including the current year covering 73.8 %, in the last 15 years including the current year covering 81.3 %. Results and discussion The severity of injury and the accompanying inflammatory factors would characterize a rapid resolution or a more severe course of post-traumatic hemarthrosis during treatment. The combination of several variants of inflammation can lead to the development of complications including osteoarthritis in cases that show mechanisms of chronic systemic inflammation of low intensity being manifested at the time of injury; ankylosis of the joint resulting from chronic systemic inflammation of low intensity involving degenerative processes. Synovitis, as a complication of post-traumatic hemarthrosis, should be differentiated with signs of low-grade inflammation, chronic course of classical inflammation and presystemic inflammation (purulent arthritis) in view of the inflammation theory. Conclusion The analysis of modern literature has shown the complexity and versatility of aspects of inflammation in posttraumatic hemarthrosis. The lack of emphasis on the assessment of the inflammatory response in rehabilitation of patients with post‑traumatic hemarthrosis can result in complications causing preconditions for the development of osteoarthritis, ankylosis, synovitis.","PeriodicalId":37426,"journal":{"name":"Genij Ortopedii","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76555090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical outcomes of patients with acetabular fractures and quadrilateral plate involvement 髋臼骨折伴四边形钢板受累患者的手术效果
Q3 Medicine Pub Date : 2023-04-01 DOI: 10.18019/1028-4427-2023-29-2-137-147
S. V. Donchenko, A. Kolesnik, V. V. Surikov, D. Ivanov, E. P. Tarasov, D. M. Yarmamedov, I. M. Solodilov
Background Open reduction and internal fixation (ORIF) remain the standard method of treating acetabular fractures. Many authors report poor results in quadrilateral plate fractures of the acetabulum with the use of ORIF. The objective was to evaluate outcomes of quadrilateral plate fractures of the acetabulum. Material and methods Surgical outcomes of 55 patients with quadrilateral plate fractures of the acetabulum were retrospectively reviewed between 2009 and 2019. Early postoperative results were followed up in 55 patients. Surgical treatment was provided for 32 (58.2 %) control patients with acetabular fractures and 23 patients (41.8 %) with quadrilateral plate fractures of the acetabulum in the main group. Long-term results were explored in 45 patients aged 18 to 60 years with acetabular fractures (control group, n = 24) and in combination with quadrilateral plate involvement (main group, n = 21). Results Surgical interventions were performed by one team consisting of the same specialists. Surgical outcomes in oth clinical groups were evaluated according to 11 criteria. Discussion The results of surgical treatment of acetabular fractures and quadrilateral plate involvement were associated with the negative impact of quadrilateral plate involvement on the duration and volume of blood loss, intraoperative and late complications and dynamics in the development of post-traumatic hip arthrosis. The results obtained were comparable with the data of the itation sources. Conclusion A comparative analysis of the outcomes suggested a negative impact of quadrilateral plate involvement on the results of surgical treatment and an objective necessity to rank quadrilateral plate fractures of the acetabulum as a risk factor for adverse outcomes with ORIF.
背景:切开复位内固定(ORIF)仍然是治疗髋臼骨折的标准方法。许多作者报道使用ORIF治疗髋臼四边形钢板骨折效果不佳。目的是评估髋臼四边形钢板骨折的疗效。材料与方法回顾性分析2009年至2019年55例髋臼四边形钢板骨折的手术结果。对55例患者进行术后早期随访。对照组32例(58.2%)髋臼骨折,主组23例(41.8%)髋臼四边钢板骨折均行手术治疗。对45例18 ~ 60岁髋臼骨折患者(对照组,n = 24)和合并四边形钢板累及(主组,n = 21)进行长期疗效观察。结果手术干预由同一专家组成的一个小组完成。根据11项标准对两组患者的手术效果进行评价。髋臼骨折和四边形钢板受累的手术治疗结果与四边形钢板受累对创伤后髋关节发展的持续时间和出血量、术中和晚期并发症以及动力学的负面影响有关。所得结果与干扰源数据具有可比性。结论通过对结果的比较分析表明,累及髋臼四边形钢板对手术治疗结果有负面影响,客观地需要将髋臼四边形钢板骨折列为ORIF不良预后的危险因素。
{"title":"Surgical outcomes of patients with acetabular fractures and quadrilateral plate involvement","authors":"S. V. Donchenko, A. Kolesnik, V. V. Surikov, D. Ivanov, E. P. Tarasov, D. M. Yarmamedov, I. M. Solodilov","doi":"10.18019/1028-4427-2023-29-2-137-147","DOIUrl":"https://doi.org/10.18019/1028-4427-2023-29-2-137-147","url":null,"abstract":"Background Open reduction and internal fixation (ORIF) remain the standard method of treating acetabular fractures. Many authors report poor results in quadrilateral plate fractures of the acetabulum with the use of ORIF. The objective was to evaluate outcomes of quadrilateral plate fractures of the acetabulum. Material and methods Surgical outcomes of 55 patients with quadrilateral plate fractures of the acetabulum were retrospectively reviewed between 2009 and 2019. Early postoperative results were followed up in 55 patients. Surgical treatment was provided for 32 (58.2 %) control patients with acetabular fractures and 23 patients (41.8 %) with quadrilateral plate fractures of the acetabulum in the main group. Long-term results were explored in 45 patients aged 18 to 60 years with acetabular fractures (control group, n = 24) and in combination with quadrilateral plate involvement (main group, n = 21). Results Surgical interventions were performed by one team consisting of the same specialists. Surgical outcomes in oth clinical groups were evaluated according to 11 criteria. Discussion The results of surgical treatment of acetabular fractures and quadrilateral plate involvement were associated with the negative impact of quadrilateral plate involvement on the duration and volume of blood loss, intraoperative and late complications and dynamics in the development of post-traumatic hip arthrosis. The results obtained were comparable with the data of the itation sources. Conclusion A comparative analysis of the outcomes suggested a negative impact of quadrilateral plate involvement on the results of surgical treatment and an objective necessity to rank quadrilateral plate fractures of the acetabulum as a risk factor for adverse outcomes with ORIF.","PeriodicalId":37426,"journal":{"name":"Genij Ortopedii","volume":"88 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75918144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The influence of extension-flexion gap imbalance on the joint function in primary total knee arthroplasty 初次全膝关节置换术中屈伸间隙不平衡对关节功能的影响
Q3 Medicine Pub Date : 2023-04-01 DOI: 10.18019/1028-4427-2023-29-2-159-166
A. Lychagin, Y. Rukin, A. Gritsyuk, Zhengyu Pang
Introduction A poorly balanced, unstable, or stiff joint is a major cause of residual pain, dissatisfaction, and revision after total knee replacement (TKA), but the definition of a well-balanced joint remains debatable. The aim of the study was to explore the influence of the knee space and the extensionflexion gap being accurately restored in primary TKA on the knee function and the quality of life of the patient. Material and methods A prospective, single-center, randomized, controlled study was performed for 41 patients with grade 3-4 knee osteoarthritis. (K-L): the first group (n = 21) underwent primary TKA with the method proposed for precise realignment of the extension-flexion gap, the second group (n = 20) underwent standard arthroplasty. The patients had CT scans of the knee performed preoperatively and postoperatively, and VAS scale pain, knee joint scales: OKS, FJS‑12, KSS (pain and function), SF-36 (parameters: PF, RP, BP, GH, VI, SF, RE, MH) were used at 3, 6 and 12 months. Results Comparison of the standing height of the joint space preoperatively and postoperatively showed a high statistical significance measuring about 20.7 % in frontal plane (group 1: 2.06 ± 2.368, group 2: 2.629 ± 2.455, р < 0.001), 28.2 % in the sagittal projection (group 1: 2.657 ± 2.143, group 2: 3.7 ± 1.717, р < 0.001), i.e., the method proposed allowed for more accurate positioning of the extension gap by 20.7 %, the flexion gap by 28.2 % and more accurate positioning of the knee space level. Preoperative and postoperative VAS, OKS, FJS-12 and SF-36 scores showed significant positive dynamics in both groups with no statistically significant difference between the groups. A statistically significant difference was seen in the functional KSS score in the groups measuring 90.6 ± 3.5 in group 1 - 12 months after surgery - and 85.6 ± 4.2 (p < 0.001) in group 2 - 12 months after surgery. Conclusion The study demonstrated the simple and effective technique proposed for positioning the flexion and extension gap of the knee joint in primary TKA and facilitated more accurate positioning of the implant and improved knee function at standard testing 12 months after surgery.
关节不平衡、不稳定或僵硬是全膝关节置换术(TKA)后残留疼痛、不满意和翻修的主要原因,但关节平衡良好的定义仍有争议。本研究旨在探讨原发性全膝关节置换术中准确恢复膝关节间隙和屈伸间隙对患者膝关节功能和生活质量的影响。材料与方法对41例3-4级膝关节骨关节炎患者进行前瞻性、单中心、随机对照研究。(K-L):第一组(n = 21)采用提出的精确调整伸屈曲间隙的方法进行初级TKA,第二组(n = 20)进行标准关节置换术。患者术前和术后均行膝关节CT扫描,并于3、6和12个月分别采用疼痛VAS评分、膝关节评分:OKS、FJS - 12、KSS(疼痛和功能)、SF-36(参数:PF、RP、BP、GH、VI、SF、RE、MH)。结果术前、术后关节间隙站立高度比较,在正位面(组1:2.06±2.368,组2:2.629±2.455,均< 0.001)、矢状面(组1:2.657±2.143,组2:2.657±2.143)分别有20.7%、28.2%的显著性差异。3.7±1.717,< 0.001),即所提出的方法允许更准确地定位20.7%的伸展间隙,28.2%的屈曲间隙和更准确地定位膝关节间隙水平。两组患者术前、术后VAS、OKS、FJS-12、SF-36评分均呈显著正动态,组间差异无统计学意义。两组术后1 ~ 12个月功能性KSS评分为90.6±3.5,术后2 ~ 12个月功能性KSS评分为85.6±4.2,差异有统计学意义(p < 0.001)。结论本研究证明了在原发性全膝关节置换术中定位膝关节屈伸间隙的简单有效的技术,有助于在术后12个月的标准测试中更准确地定位假体并改善膝关节功能。
{"title":"The influence of extension-flexion gap imbalance on the joint function in primary total knee arthroplasty","authors":"A. Lychagin, Y. Rukin, A. Gritsyuk, Zhengyu Pang","doi":"10.18019/1028-4427-2023-29-2-159-166","DOIUrl":"https://doi.org/10.18019/1028-4427-2023-29-2-159-166","url":null,"abstract":"Introduction A poorly balanced, unstable, or stiff joint is a major cause of residual pain, dissatisfaction, and revision after total knee replacement (TKA), but the definition of a well-balanced joint remains debatable. The aim of the study was to explore the influence of the knee space and the extensionflexion gap being accurately restored in primary TKA on the knee function and the quality of life of the patient. Material and methods A prospective, single-center, randomized, controlled study was performed for 41 patients with grade 3-4 knee osteoarthritis. (K-L): the first group (n = 21) underwent primary TKA with the method proposed for precise realignment of the extension-flexion gap, the second group (n = 20) underwent standard arthroplasty. The patients had CT scans of the knee performed preoperatively and postoperatively, and VAS scale pain, knee joint scales: OKS, FJS‑12, KSS (pain and function), SF-36 (parameters: PF, RP, BP, GH, VI, SF, RE, MH) were used at 3, 6 and 12 months. Results Comparison of the standing height of the joint space preoperatively and postoperatively showed a high statistical significance measuring about 20.7 % in frontal plane (group 1: 2.06 ± 2.368, group 2: 2.629 ± 2.455, р < 0.001), 28.2 % in the sagittal projection (group 1: 2.657 ± 2.143, group 2: 3.7 ± 1.717, р < 0.001), i.e., the method proposed allowed for more accurate positioning of the extension gap by 20.7 %, the flexion gap by 28.2 % and more accurate positioning of the knee space level. Preoperative and postoperative VAS, OKS, FJS-12 and SF-36 scores showed significant positive dynamics in both groups with no statistically significant difference between the groups. A statistically significant difference was seen in the functional KSS score in the groups measuring 90.6 ± 3.5 in group 1 - 12 months after surgery - and 85.6 ± 4.2 (p < 0.001) in group 2 - 12 months after surgery. Conclusion The study demonstrated the simple and effective technique proposed for positioning the flexion and extension gap of the knee joint in primary TKA and facilitated more accurate positioning of the implant and improved knee function at standard testing 12 months after surgery.","PeriodicalId":37426,"journal":{"name":"Genij Ortopedii","volume":"196 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72772714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The possibilities of drilled tunneling in the treatment of knee joint osteoarthritis 钻孔隧道治疗膝关节骨关节炎的可能性
Q3 Medicine Pub Date : 2023-04-01 DOI: 10.18019/1028-4427-2023-29-2-204-210
A. A. Baranovskii, А.G. Balgley, A. Tkachenko, D. Mansurov, A. Khromov
Introduction Surgical treatment of knee osteoarthritis is a controversial issue. Knee replacement is the treatment of choice in the orthopedic practice for patients with severe knee osteoarthritis. However, total knee arthroplasty (TKA) has not only beneficial results and implant survivorship is limited in time. In recent years, the number of publications devoted to the limitation of indications for TKA in patients with osteoarthritis has been increased. The use of drilled tunneling in its modern modifications enables to delay or, in some cases, avoid knee joint arthroplasty. Purpose To substantiate the safety, low invasiveness and effectiveness of the tunneling method as a minimally invasive organ-preserving treatment for knee joint osteoarthritis. Materials and methods The electronic Pub-Med/MEDLINE and eLibrary databases were searched for works published for the last 30 years. The search was carried out with keywords and phrases: knee joint osteoarthritis, articular cartilage, bone drilling, arthroscopy of the knee joint. Results The effectiveness of tunneling is based on the concept of simultaneous revascularization, drainage and decompression of the subchondral sections of the knee joint and the medullary cavity of the tubular bones. Up to 96 % of patients report a positive effect of tunneling immediately after surgery. Intraosseous pressure decreases for up to 2 years in 88 % of patients. Discussion The tunneling method in the treatment of knee osteoarthritis helps to reduce pain in the projection of the femur and tibia, including night pain, improves the functional parameters of the joint, inhibits the progress of cartilage destruction, improves the quality of life of patients and reduces the need for replacement of the affected joint. In addition, tunneling does not require serious economic costs. Due to the fact that this method is a minimally invasive surgical intervention, the risk of infection is noticeably lower than with TKA. Conclusion Thus, the tunneling of the articular ends is a simple, safe, low invasive and effective method of treating knee joint osteoarthritis.
膝关节骨关节炎的手术治疗是一个有争议的问题。膝关节置换术是严重膝骨关节炎患者骨科治疗的首选方法。然而,全膝关节置换术(TKA)不仅有良好的效果,而且假体的存活时间有限。近年来,专门讨论骨关节炎患者TKA适应症限制的出版物数量有所增加。在其现代修改中使用钻孔隧道可以延迟或在某些情况下避免膝关节置换术。目的探讨隧道法作为一种微创保器官治疗膝关节骨性关节炎的安全性、低侵入性和有效性。材料与方法检索pubm - med /MEDLINE电子数据库和图书馆数据库,检索近30年发表的文献。搜索的关键词和短语是:膝关节骨性关节炎,关节软骨,骨钻孔,膝关节关节镜检查。结果隧道术的有效性是建立在膝关节软骨下段和管状骨髓腔同时血运重建、引流和减压的基础上的。高达96%的患者在手术后立即报告隧道治疗的积极效果。88%的患者骨内压力下降可达2年。隧道法治疗膝关节骨性关节炎有助于减轻股骨和胫骨突出部位的疼痛,包括夜间疼痛,改善关节的功能参数,抑制软骨破坏的进展,提高患者的生活质量,减少对受影响关节的置换需求。此外,隧道开挖不需要严重的经济成本。由于这种方法是一种微创手术干预,感染的风险明显低于TKA。结论关节末端隧道术是治疗膝关节骨性关节炎的一种简单、安全、低创、有效的方法。
{"title":"The possibilities of drilled tunneling in the treatment of knee joint osteoarthritis","authors":"A. A. Baranovskii, А.G. Balgley, A. Tkachenko, D. Mansurov, A. Khromov","doi":"10.18019/1028-4427-2023-29-2-204-210","DOIUrl":"https://doi.org/10.18019/1028-4427-2023-29-2-204-210","url":null,"abstract":"Introduction Surgical treatment of knee osteoarthritis is a controversial issue. Knee replacement is the treatment of choice in the orthopedic practice for patients with severe knee osteoarthritis. However, total knee arthroplasty (TKA) has not only beneficial results and implant survivorship is limited in time. In recent years, the number of publications devoted to the limitation of indications for TKA in patients with osteoarthritis has been increased. The use of drilled tunneling in its modern modifications enables to delay or, in some cases, avoid knee joint arthroplasty. Purpose To substantiate the safety, low invasiveness and effectiveness of the tunneling method as a minimally invasive organ-preserving treatment for knee joint osteoarthritis. Materials and methods The electronic Pub-Med/MEDLINE and eLibrary databases were searched for works published for the last 30 years. The search was carried out with keywords and phrases: knee joint osteoarthritis, articular cartilage, bone drilling, arthroscopy of the knee joint. Results The effectiveness of tunneling is based on the concept of simultaneous revascularization, drainage and decompression of the subchondral sections of the knee joint and the medullary cavity of the tubular bones. Up to 96 % of patients report a positive effect of tunneling immediately after surgery. Intraosseous pressure decreases for up to 2 years in 88 % of patients. Discussion The tunneling method in the treatment of knee osteoarthritis helps to reduce pain in the projection of the femur and tibia, including night pain, improves the functional parameters of the joint, inhibits the progress of cartilage destruction, improves the quality of life of patients and reduces the need for replacement of the affected joint. In addition, tunneling does not require serious economic costs. Due to the fact that this method is a minimally invasive surgical intervention, the risk of infection is noticeably lower than with TKA. Conclusion Thus, the tunneling of the articular ends is a simple, safe, low invasive and effective method of treating knee joint osteoarthritis.","PeriodicalId":37426,"journal":{"name":"Genij Ortopedii","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86039092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rationale for choosing a spacer at the first treatment stage for late deep periprosthetic knee joint infection 在晚期深度假体周围膝关节感染的第一治疗阶段选择垫片的理由
Q3 Medicine Pub Date : 2023-04-01 DOI: 10.18019/1028-4427-2023-29-2-173-179
S. Linnik, A. Afinogenova, G.E. finogenov, A. Spiridonova, Y. Tsololo, G. Karagezov, V.M. Khaidarov, D.V. Kravtsov, I. Kucheev, A. Khromov, I. Abbas, M.V. Maryshev
Background Periprosthetic infection develops in 0.5 to 5.0 % of cases after knee replacement, which is a social and economic problem. The most common causes of periprosthetic infection are methicillin-resistant staphylococcus aureus (MRSA) (36 %), gram-negative bacteria, and microbial associations. The study was aimed at improving the results of the sanitizing stage of revision arthroplasty in patients with periprosthetic infection of the knee joint by a developed long-acting antimicrobial composition and improving the designs of articulating spacers of the knee joint. Materials and Methods The treatment results of 121 patients with knee joint periprosthetic infection were analyzed. Nine patients had an early periprosthetic infection and 112 had a late one. Patients in satisfactory condition with stable implant components who had early periprosthetic infection underwent surgical treatment of the purulent focuses, replacement of a polyethylene tibial insert, thorough surgical wound washing using pulse lavage, drainage, and VAC-therapy. Patients with late periprosthetic infection were divided into 3 groups on the basis of the spacer used. An articulating spacer based on the developed antimicrobial composition of prolonged action (RU 191236 patent) was used in 59 patients of the first group. Preformed spacers were implanted in 29 patients of the second group, and 18 patients of the third group got a block-shaped spacer. Results An antibacterial anti-adhesive non-toxic composition with a prolonged action based on bone cement with gentamicin and such antiseptics as poviargol, dioxydine, and high-molecular polyvinylpyrrolidone has been developed. All the patients underwent the sanitizing stage of revision arthroplasty, implant removal, and spacer installation. Periprosthetic infection recurrence developed in 3 patients of the first group, 9 patients of the second group and 7 patients of the third one. The average time from the sanitizing stage to the second final stage of revision was 3-6 (4.8 ± 1.9) months. Discussion According to scientific data, the impregnation of new antibiotics into bone cement with gentamicin does not improve the antimicrobial effect of a spacer, especially in case of antibiotic-resistant strains. Block-shaped and preformed spacers lead to infection recurrence and complications. Antiseptic impregnation with different mechanisms of action is able to affect antibiotic-resistant bacteria, and the polymer is able to prolong the effect. Conclusion The use of articulating spacers for the knee joint, which include an antimicrobial composition, allows preserving the function of the joint and reducing the number of infectious complications, which facilitates the final stage of revision arthroplasty.
背景:膝关节置换术后假体周围感染发生率为0.5% ~ 5.0%,是一个社会经济问题。假体周围感染最常见的原因是耐甲氧西林金黄色葡萄球菌(MRSA)(36%)、革兰氏阴性菌和微生物关联。该研究旨在通过开发长效抗菌组合物改善膝关节假体周围感染患者翻修关节置换术消毒阶段的结果,并改进膝关节关节间隔物的设计。材料与方法对121例膝关节假体周围感染患者的治疗结果进行分析。早期感染9例,晚期感染112例。早期假体周围感染的患者情况满意,植入物稳定,手术治疗化脓性病灶,置换聚乙烯胫骨插入物,用脉冲灌洗、引流彻底清洗手术伤口,并进行vaca治疗。晚期假体周围感染患者根据使用间隔器的不同分为3组。基于所开发的长效抗菌组合物(RU 191236专利)的关节间隔剂用于第一组59例患者。第二组29例植入预成型垫片,第三组18例植入块状垫片。结果在庆大霉素骨水泥的基础上,研制出了一种长效抗菌抗粘接无毒组合物,该组合物由聚维亚戈、二氧吡啶、高分子聚乙烯吡咯烷酮等防腐剂组成。所有患者均经历了翻修关节置换术、取出假体和安装垫片的消毒阶段。第一组3例假体周围感染复发,第二组9例,第三组7例。从消毒阶段到第二次翻修的平均时间为3-6(4.8±1.9)个月。科学数据表明,庆大霉素在骨水泥中浸渍新型抗生素并不能提高间隔剂的抗菌效果,特别是在耐药菌株的情况下。块状和预成型垫片导致感染复发和并发症。不同作用机制的抗菌剂浸渍都能对耐药菌产生影响,而聚合物能延长这种作用。结论膝关节使用含抗菌成分的关节垫片,可以保留关节功能,减少感染并发症的数量,有利于关节翻修成形术的最后阶段。
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引用次数: 0
Analysis of leukocyte indices in patients with revision hip arhtroplasty 髋关节翻修成形术患者白细胞指标分析
Q3 Medicine Pub Date : 2023-04-01 DOI: 10.18019/1028-4427-2023-29-2-155-158
E. Matveeva, A. Gasanova, E. Spirkina, A. M. Ermakov
Introduction The widespread application of large joint arthroplasty is accompanied by an increase in the complications associated with periprosthetic infection. Currently, treating patients with infectious complications in the area of large joint arthroplasty remains a relevant issue. Purpose To determine the prognostic value of leukocyte indices in patients with revision hip arthroplasty. Materials and methods The study involved 88 patients with revision hip arthroplasty hospitalized at the Ilizarov National Medical Research Centre for Traumatology and Orthopedics. The patients were divided into two groups: group 1 (n = 77) were patients without periprosthetic infection (mean age 60.1 ± 1.5 years) and group 2 (n = 11) were patients with periprosthetic infection (age 55, 2 ± 4.7 years). An analysis of the preoperative results of determining the number of leukocytes and leukocyte formula was carried out with the calculation of the leukocyte index of intoxication and the resistance index of the organism. The reliability of differences in indicators in groups was determined. According to the odds ratio, the probability of developing an infectious process was estimated. Results The level of leukocytes in the blood serum and the leukocyte index of intoxication of patients of groups 1 and 2 had no significant differences. In patients with an infectious process, their level was higher by 19.7 %, however, not going beyond the normal range. Differences in the index of intoxication in patients of groups 1 and 2 were not noted. In the 2nd group of patients, the resistance index of the organism significantly exceeded that of the 1st group, remaining within the normal range in both groups. When calculating the prognosis for the development of infectious complications, the value of the odds ratio for the resistance index of the organism is exactly an order of magnitude higher than this indicator for leukocytes and the leukocyte index of intoxication. Conclusion The prognosis of the clinical situation in revision hip arthroplasty should consider not only local changes and the general condition of the patient, but also an assessment of laboratory parameters, in particular, the resistance index of the body.
大关节置换术的广泛应用伴随着假体周围感染并发症的增加。目前,大关节置换术中感染性并发症的治疗仍然是一个相关的问题。目的探讨白细胞指标对人工髋关节翻修术患者预后的价值。材料和方法本研究纳入了在Ilizarov国家创伤和骨科医学研究中心住院的88例翻修髋关节置换术患者。将患者分为两组,第一组(n = 77)为无假体周围感染患者(平均年龄60.1±1.5岁),第二组(n = 11)为假体周围感染患者(平均年龄55,2±4.7岁)。对术前白细胞计数和白细胞配方测定结果进行分析,计算中毒白细胞指数和机体耐药指数。测定各组指标差异的信度。根据比值比,估计发生感染过程的概率。结果1、2组患者血清白细胞水平及中毒白细胞指数差异无统计学意义。在有感染过程的患者中,其水平升高19.7%,但未超出正常范围。1组和2组患者的中毒指数未见差异。第二组患者的耐药指数明显超过第一组,两组均在正常范围内。在计算感染性并发症发展的预后时,机体耐药指数的优势比值正好比白细胞和中毒白细胞指数的优势比值高一个数量级。结论对髋关节翻修成形术患者的临床预后,不仅要考虑患者的局部变化和全身情况,还要综合考虑实验室指标,尤其是机体阻力指数。
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Genij Ortopedii
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