Pub Date : 2022-01-01Epub Date: 2022-07-25DOI: 10.1007/s40675-022-00226-5
Cristina Frange, Giuliano Paz de Oliveira, Fernando Morgadinho Santos Coelho
Purpose of review: Central nervous system (CNS) hypersomnias can be triggered by external factors, such as infection or as a response to vaccination. The 2019 coronavirus disease (COVID-19) pandemic, which was caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), led to a worldwide effort to quickly develop a vaccine to contain the pandemic and reduce morbidity and mortality. This narrative review is focused on the literature published in the past 2 years and provides an update on current knowledge in respect of the triggering of CNS hypersomnias by infection per se, vaccination, and circadian rhythm alterations caused by social isolation, lockdown, and quarantine.
Recent findings: At present, there is no consensus on the association between hypersomnias and COVID-19 vaccination or infection per se; however, the data suggest that there has been an increase in excessive daytime sleepiness due to vaccination, but only for a short duration. Kleine Levin syndrome, hypersomnia, excessive daytime sleepiness, and narcolepsy were aggravated and exacerbated in some case reports in the literature. Both increased and decreased sleep duration and improved and worsened sleep quality were described. In all age groups, delayed sleep time was frequent in studies of patients with hypersomnolence.
Summary: The hypothesis that there is a pathophysiological mechanism by which the virus, vaccination, and the effects of quarantine aggravate hypersomnias is discussed in this review.
{"title":"COVID-19 and Central Nervous System Hypersomnias.","authors":"Cristina Frange, Giuliano Paz de Oliveira, Fernando Morgadinho Santos Coelho","doi":"10.1007/s40675-022-00226-5","DOIUrl":"https://doi.org/10.1007/s40675-022-00226-5","url":null,"abstract":"<p><strong>Purpose of review: </strong>Central nervous system (CNS) hypersomnias can be triggered by external factors, such as infection or as a response to vaccination. The 2019 coronavirus disease (COVID-19) pandemic, which was caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), led to a worldwide effort to quickly develop a vaccine to contain the pandemic and reduce morbidity and mortality. This narrative review is focused on the literature published in the past 2 years and provides an update on current knowledge in respect of the triggering of CNS hypersomnias by infection per se<i>,</i> vaccination, and circadian rhythm alterations caused by social isolation, lockdown, and quarantine.</p><p><strong>Recent findings: </strong>At present, there is no consensus on the association between hypersomnias and COVID-19 vaccination or infection per se<i>;</i> however, the data suggest that there has been an increase in excessive daytime sleepiness due to vaccination, but only for a short duration. Kleine Levin syndrome, hypersomnia, excessive daytime sleepiness, and narcolepsy were aggravated and exacerbated in some case reports in the literature. Both increased and decreased sleep duration and improved and worsened sleep quality were described. In all age groups, delayed sleep time was frequent in studies of patients with hypersomnolence.</p><p><strong>Summary: </strong>The hypothesis that there is a pathophysiological mechanism by which the virus, vaccination, and the effects of quarantine aggravate hypersomnias is discussed in this review.</p>","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309232/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40573968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-01Epub Date: 2021-10-03DOI: 10.1007/s40675-021-00218-x
Qingchao Qiu, Jason H Mateika
The following review is designed to explore the pathophysiology of sleep apnea in aging women. The review initially introduces four endotypes (i.e., a more collapsible airway, upper airway muscle responsiveness, arousal threshold, and loop gain) that may have a role in the initiation of obstructive sleep apnea. Thereafter, sex differences in the prevalence of sleep apnea are considered along with differences in the prevalence that exist between younger and older women. Following this discussion, we consider how each endotype might contribute to the increase in prevalence of sleep apnea in aging women. Lastly, we address how modifications in one form of respiratory plasticity, long-term facilitation, that might serve to mitigate apneic events in younger women may be modified in aging women with obstructive sleep apnea. Overall, the published literature indicates that the prevalence of sleep apnea is increased in aging women. This increase is linked primarily to a more collapsible airway and possibly to reduced responsiveness of upper airway muscle activity. In contrast, modifications in loop gain or the arousal threshold do not appear to have a role in the increased prevalence of sleep apnea in aging women. Moreover, we suggest that mitigation of long-term facilitation could contribute to the increased prevalence of sleep apnea in aging women.
{"title":"Pathophysiology of Obstructive Sleep Apnea in Aging Women.","authors":"Qingchao Qiu, Jason H Mateika","doi":"10.1007/s40675-021-00218-x","DOIUrl":"https://doi.org/10.1007/s40675-021-00218-x","url":null,"abstract":"<p><p>The following review is designed to explore the pathophysiology of sleep apnea in aging women. The review initially introduces four endotypes (i.e., a more collapsible airway, upper airway muscle responsiveness, arousal threshold, and loop gain) that may have a role in the initiation of obstructive sleep apnea. Thereafter, sex differences in the prevalence of sleep apnea are considered along with differences in the prevalence that exist between younger and older women. Following this discussion, we consider how each endotype might contribute to the increase in prevalence of sleep apnea in aging women. Lastly, we address how modifications in one form of respiratory plasticity, long-term facilitation, that might serve to mitigate apneic events in younger women may be modified in aging women with obstructive sleep apnea. Overall, the published literature indicates that the prevalence of sleep apnea is increased in aging women. This increase is linked primarily to a more collapsible airway and possibly to reduced responsiveness of upper airway muscle activity. In contrast, modifications in loop gain or the arousal threshold do not appear to have a role in the increased prevalence of sleep apnea in aging women. Moreover, we suggest that mitigation of long-term facilitation could contribute to the increased prevalence of sleep apnea in aging women.</p>","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865406/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39959476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-01DOI: 10.1007/s40675-021-00219-w
Inbal Hazkani, N. Raol
{"title":"Hypoglossal Nerve Stimulation for Treatment of Severe Refractory Obstructive Sleep Apnea in Children with Down Syndrome","authors":"Inbal Hazkani, N. Raol","doi":"10.1007/s40675-021-00219-w","DOIUrl":"https://doi.org/10.1007/s40675-021-00219-w","url":null,"abstract":"","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44942919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-25DOI: 10.1007/s40675-021-00221-2
M. Pascoe, N. Foldvary-Schaefer
{"title":"Pregnancy and Contraception in Central Hypersomnolence Disorders","authors":"M. Pascoe, N. Foldvary-Schaefer","doi":"10.1007/s40675-021-00221-2","DOIUrl":"https://doi.org/10.1007/s40675-021-00221-2","url":null,"abstract":"","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49043581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-10-07DOI: 10.1007/s40675-021-00217-y
Takeshi Matsumoto, T. Hirai, K. Chin
{"title":"Evidence of an Association of Obstructive Sleep Apnea with Diabetes and Diabetic Complications","authors":"Takeshi Matsumoto, T. Hirai, K. Chin","doi":"10.1007/s40675-021-00217-y","DOIUrl":"https://doi.org/10.1007/s40675-021-00217-y","url":null,"abstract":"","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2021-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47662380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-17DOI: 10.1007/s40675-021-00212-3
E. Tan, Chi‐Hang Lee
{"title":"Obstructive Sleep Apnea and Arrhythmias in the Elderly","authors":"E. Tan, Chi‐Hang Lee","doi":"10.1007/s40675-021-00212-3","DOIUrl":"https://doi.org/10.1007/s40675-021-00212-3","url":null,"abstract":"","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2021-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40675-021-00212-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47367101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-04DOI: 10.1007/s40675-021-00214-1
E. D. de Bruin, J. Dewald-Kaufmann
{"title":"What Is “Chronic” in “Chronic Sleep Reduction” and What Are Its Consequences? A Systematic Scoping Review of the Literature","authors":"E. D. de Bruin, J. Dewald-Kaufmann","doi":"10.1007/s40675-021-00214-1","DOIUrl":"https://doi.org/10.1007/s40675-021-00214-1","url":null,"abstract":"","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2021-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40675-021-00214-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46161170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-23DOI: 10.1007/s40675-021-00215-0
Jeeyun Ahn, M. Gorin
{"title":"The Associations of Obstructive Sleep Apnea and Eye Disorders: Potential Insights into Pathogenesis and Treatment","authors":"Jeeyun Ahn, M. Gorin","doi":"10.1007/s40675-021-00215-0","DOIUrl":"https://doi.org/10.1007/s40675-021-00215-0","url":null,"abstract":"","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2021-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40675-021-00215-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46282078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-20DOI: 10.1007/s40675-021-00213-2
S. Khatibi, M. Kazemi, Saeideh Zenoozian, M. Vakili, R. Kharaghani
{"title":"Cognitive Behavioral Counseling and Sleep Quality in Pregnant Women: a Randomized Controlled Trial","authors":"S. Khatibi, M. Kazemi, Saeideh Zenoozian, M. Vakili, R. Kharaghani","doi":"10.1007/s40675-021-00213-2","DOIUrl":"https://doi.org/10.1007/s40675-021-00213-2","url":null,"abstract":"","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2021-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40675-021-00213-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43392331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-15DOI: 10.1007/s40675-021-00211-4
I. Imayama, A. Sahni, S. Sunkara, B. Prasad
{"title":"Sleep Apnea and Hypertension in the Elderly","authors":"I. Imayama, A. Sahni, S. Sunkara, B. Prasad","doi":"10.1007/s40675-021-00211-4","DOIUrl":"https://doi.org/10.1007/s40675-021-00211-4","url":null,"abstract":"","PeriodicalId":37449,"journal":{"name":"Current Sleep Medicine Reports","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2021-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40675-021-00211-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45608251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号