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Comparison of the Therapeutic Effects of a Pigtail Catheter and Chest Tube in the Treatment of Spontaneous Pneumothorax: A Randomized Clinical Trial Study. 猪尾管与胸管治疗自发性气胸的疗效比较:一项随机临床研究。
IF 0.9 Q4 RESPIRATORY SYSTEM Pub Date : 2021-11-01 DOI: 10.5152/TurkThoracJ.2021.20281
Seyed Ziaeddin Rasihashemi, Ali Ramouz, Hassan Amini

Objective: The purpose of this study was to compare the therapeutic effects of a pigtail catheter with a chest tube in the management of patients with spontaneous pneumothorax (SP).

Material and methods: A randomized controlled trial study was performed on patients with SP from August 2016 to December 2017 at Imam Reza Hospital, Tabriz, Iran. Forty-four patients were randomly assigned into 2 groups: group A with a 14-Fr pigtail catheter and group B using a 28-Fr chest tube. Two patients were excluded from the study.

Results: Forty-two patients participated in the study with 21 patients in each group. There were no significant differences between the groups in the patients' baseline data. The success rate was higher in patients with pigtail catheters (85.7%) than in patients with chest tubes (76.2%). However, the difference was not significant (P = .43). The procedure time was significantly shorter in the pigtail group compared to the chest tube group (P < .01). According to the visual analog scale (VAS), patients with pigtail catheters experienced milder pain during tube insertion than patients with chest tubes (P = .02). However, the pain score at the insertion site was not significantly different between the 2 groups for the first 2 days after the procedure. Patients with pigtail catheters experienced significantly less pain than patients with chest tubes during removal of the tube (P < .01). Also, there was no significant difference between the pain experienced by the 2 groups at the time of hospital discharge (P = .19). Analgesic drug usage was lower in patients with pigtail catheters compared to patients with chest tubes (P < .01). There was a trend toward lower median hospital stays demonstrated by patients with pigtail catheters compared to patients with chest tubes (P = .2).

Conclusion: Pigtail catheters might be as effective as chest tubes for treating patients with SP in terms of lung re-expansion.

目的:本研究的目的是比较猪尾导管与胸管在治疗自发性气胸(SP)患者中的疗效。材料与方法:2016年8月至2017年12月在伊朗大不里士伊玛目礼萨医院对SP患者进行随机对照试验研究。44例患者随机分为2组:A组采用14fr细尾导管,B组采用28fr胸管。两名患者被排除在研究之外。结果:共42例患者参与研究,每组21例。两组患者的基线数据无显著差异。使用短尾导管的成功率(85.7%)高于使用胸管的成功率(76.2%)。但差异无统计学意义(P = 0.43)。辫子组手术时间明显短于胸管组(P < 0.01)。根据视觉模拟评分(visual analogue scale, VAS),猪尾管患者在置管过程中疼痛程度较胸管患者轻(P = 0.02)。然而,在手术后的前2天,两组在插入部位的疼痛评分没有显著差异。在拔管过程中,使用辫状导管的患者比使用胸管的患者疼痛明显减轻(P < 0.01)。两组患者出院时疼痛程度差异无统计学意义(P = 0.19)。使用猪尾导管的患者镇痛药物用量低于使用胸管的患者(P < 0.01)。与胸管患者相比,使用辫子导管的患者的住院时间中位数较低(P = 0.2)。结论:猪尾导管治疗SP患者肺再扩张的效果与胸管相同。
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引用次数: 3
Association Between Cystic Fibrosis Severity Markers and CFTR Genotypes in Turkish Children. 土耳其儿童囊性纤维化严重程度标记物与CFTR基因型之间的关系
IF 0.9 Q4 RESPIRATORY SYSTEM Pub Date : 2021-11-01 DOI: 10.5152/TurkThoracJ.2021.20282
Abdurrahman Erdem Başaran, Ayşen Başaran, Dilara Fatma Kocacik Uygun, Elanur Yılmaz, Asef Moballegh, Latife Öz, Özgül Alper, Ayşen Bingöl

Objective: To compare class I/II cystic fibrosis transmembrane conductance regulator (CFTR) mutations to class III-V mutations with regards to cystic fibrosis disease severity markers in children.

Material and methods: This study was designed as a cross-sectional study in Antalya province, located on the south coast of Turkey. The study included 38 cystic fibrosis patients aged between 0.6 and 18 years. The CFTR genotype of the patients was categorized into 2 groups based on the presence or absence of class I or class II mutations in any of the alleles. Group I comprised 8 homozygous, 8 with unknown alleles, and 8 compound heterozygous patients, and group II comprised 11 homozygous and 3 compound heterozygous patients. The groups were analyzed in respect of cystic fibrosis disease severity markers, such as spirometry, ShwachmanKulczycki score, body mass index (BMI), sweat chloride concentration, chronic Pseudomonas aeruginosa infection, annual exacerbation frequency, and severe exacerbations requiring hospitalization during the previous year.

Results: In the comparison of group I and group II patients, a significant difference was observed in pancreas insufficiency (83.3% vs. 35.7%; P = .005), chronic P. aeruginosa infection (58.3% vs. 7.1%; P = .002), cough severity score (1.7 ± 1.1 vs. 0.9 ± 1.5; P = .029), number of severe exacerbations requiring hospitalization during the previous year (0.9 ± 1 vs. 0.3 ± 0.8; P = .03), and sweat chloride levels (76.7 ± 15.2 vs. 61 ± 22.3; P = .02). All these values were higher in group I patients. The mean BMI values (15.8 ± 2.2 vs. 17.6 ± 2.8; P = .03) were lower in group I patients.

Conclusion: There seems to be a difference between class I/II CFTR mutations and class III-V mutations on the severity of the disease in cystic fibrosis patients.

目的:比较I/II类囊性纤维化跨膜传导调节因子(CFTR)突变与III-V类突变对儿童囊性纤维化疾病严重程度标志物的影响。材料和方法:本研究在位于土耳其南部海岸的安塔利亚省设计为横断面研究。该研究包括38名年龄在0.6至18岁之间的囊性纤维化患者。根据任何等位基因中是否存在I类或II类突变,将患者的CFTR基因型分为两组。ⅰ组纯合子8例,等位基因未知8例,复合杂合子8例;ⅱ组纯合子11例,复合杂合子3例。分析各组囊性纤维化疾病严重程度指标,如肺活量测定、ShwachmanKulczycki评分、体重指数(BMI)、汗液氯化物浓度、慢性铜绿假单胞菌感染、年加重频率、前一年需要住院治疗的严重加重。结果:I组与II组患者胰腺功能不全比较,差异有统计学意义(83.3% vs. 35.7%;P = 0.005),慢性铜绿假单胞菌感染(58.3% vs. 7.1%;P = .002),咳嗽严重程度评分(1.7±1.1∶0.9±1.5;P = 0.029),前一年需要住院治疗的严重恶化次数(0.9±1比0.3±0.8;P = .03),汗液氯化物水平(76.7±15.2∶61±22.3;P = .02)。所有这些数值在I组患者中都更高。平均BMI值(15.8±2.2 vs. 17.6±2.8;P = .03)较ⅰ组患者低。结论:在囊性纤维化患者中,I/II类CFTR突变与III-V类CFTR突变在疾病严重程度上似乎存在差异。
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引用次数: 0
Tobacco Containing Scenes in Some Selected Turkish Movies Released Between 1992 and 2016. 1992年至2016年上映的一些精选土耳其电影中含有烟草的场景。
IF 0.9 Q4 RESPIRATORY SYSTEM Pub Date : 2021-11-01 DOI: 10.5152/TurkThoracJ.2021.20291
Hanife Ece Erik, Merve Colaklar, Egemen Yildiz, Aişe Esra Gülçek, Bilgin Percin, Cağlar Aktas, Cağrı Özbeyaz, Fati Gözde Sebnem Tokmak, Mervenur Demir Çuha, Mustafa Doğru, Polat Ercan, Aslı Kuzu, Deniz Aral Özbek, Eda Dölek, Fadime Eda Koç, Büşra Solak, Mahmut Yardım, Hilal Özcebe

Objective: Movies are among the most widely used media for advertising, promotional, and sponsorship activities of the tobacco industry, and the industry has been making huge investments in this sector for many years. In this study, the effects of movie scenes depicting the use of tobacco products, and the possible effects of the laws governing such scenes, were examined.

Material and methods: The sample of the study consisted of 50 films, the first 2 of which were the most watched each year, between the years 1992 and 2016, according to the data of the Center for Turkish Cinema Studies and the boxofficeturkiye.com websites. The scenes depicting the use of tobacco products were analyzed using the data collection form developed by the researchers. Each movie was evaluated separately by 2 researchers.

Results: A tobacco product was used in 82% of the 50 films watched. Men (87%), individuals between the ages of 25 and 64 (78.0%), and leading actors (40%) used more tobacco products, and the most frequently used product was the cigarette (93.1%). The number andduration of scenes containing tobacco was greater by 1.6 times before the first law was passed, and between the passage of the first law and the passage of the second law (P > .05, P > .05). The number and duration of the scenes decreased between the passage of the first and the second laws and after the second law was passed, by 3.6 and 5.3 times, respectively (P < .05, P < .05).

Conclusion: Consistent and comprehensive tobacco control policies have been effective in reducing the number of scenes that contain tobacco in the movies produced in Turkey. A comprehensive and multidisciplinary approach is required to overcome the tobacco industry's impact on cinema.

目的:电影是烟草行业广告、促销和赞助活动中使用最广泛的媒体之一,烟草行业多年来一直在这一领域进行巨额投资。在这项研究中,研究了描绘烟草产品使用的电影场景的影响,以及管理此类场景的法律可能产生的影响。材料和方法:根据土耳其电影研究中心和boxofficeturkiye.com网站的数据,研究样本包括50部电影,其中前两部是1992年至2016年间每年观看人数最多的电影。使用研究人员开发的数据收集表格对描绘烟草产品使用的场景进行了分析。每部电影分别由2名研究人员进行评估。结果:在观看的50部电影中,有82%使用了烟草制品。男性(87%)、25岁至64岁人群(78.0%)和主要演员(40%)使用更多的烟草制品,最常使用的产品是香烟(93.1%)。烟草场景的数量和持续时间在第一法律通过前、第一法律通过与第二法律通过之间是1.6倍(P > 0.05, P > 0.05)。在第一法和第二法通过期间和第二法通过后,场景数量和时长分别减少了3.6倍和5.3倍(P < 0.05, P < 0.05)。结论:一贯和全面的控烟政策在减少土耳其制作的电影中含有烟草的场景数量方面是有效的。需要一种全面和多学科的方法来克服烟草业对电影的影响。
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引用次数: 0
Facing the Pandemic: Burnout in Physicians in Turkey. 面对流行病:土耳其医生的职业倦怠。
IF 0.9 Q4 RESPIRATORY SYSTEM Pub Date : 2021-11-01 DOI: 10.5152/TurkThoracJ.2021.20240
Şengül Tarhan, Gökçen Ömeroğlu Şimşek, Neşe Direk Tecirli, Eyup Sabri Uçan, Merve Atik, Bahriye Oya İtil, Oğuz Kılınç

Objective: During the COVID-19 pandemic, physicians have been working for long hours, with the fear of contracting the disease and infecting their families. Therefore, there are great concerns about the mental health of physicians. In this research, we aimed to reveal the factors that affect the burnout among physicians working during the pandemic.

Material and methods: This is a cross-sectional study involving physicians working during the pandemic in health institutions that admit COVID-19 patients. A questionnaire form consisting of the "Sociodemographic Data Form" and the "Maslach Burnout Inventory (MBI)" was used. The questionnaire was sent to the contact numbers of physicians via the internet. The target population was reached through the communication groups of the Turkish Thoracic Society and other professional associations, the communication groups of health institutions, and also through personal correspondence. Burnout was evaluated with the scores of each participant from the 3 subscales of Emotional Exhaustion (EE), Depersonalization (DP), and Lack of Accomplishment (LA).

Results: Of the 1177 physicians who participated in the survey, 893 answered the survey completely. Females comprised 56.70% (n = 506) of the respondents, and the mean age was 38.63 (±11.65). The residents (41%, n = 366) and specialists (31%, n = 277) made up the majority of the physicians. Eighty-six percent (n = 768) of the physicians had difficulty in obtaining personal protective equipment (PPE). It was determined that 81.7% (n = 730) of the 893 physicians were actively working in pandemic units (outpatient clinics, emergencies, inpatient clinics, intensive care units), and burnout was significantly higher in these physicians (P < .01). After excluding other confounding factors by regression analysis, their Maslach total scores and EE scores were found to be significantly high (P = .001).

Conclusion: Working in pandemic units and facing difficulty in accessing PPE are identified as the most important risk factors for burnout. Hence, we can say that working with PPE, and with the managers' discretion and support, the physicians' burnout can be prevented.

目的:在新冠肺炎大流行期间,医生长时间工作,担心感染疾病并感染家人。因此,医生的心理健康问题备受关注。在本研究中,我们旨在揭示影响大流行期间工作的医生职业倦怠的因素。材料和方法:这是一项横断面研究,涉及在大流行期间在接收COVID-19患者的卫生机构工作的医生。采用“社会人口学数据表”和“Maslach职业倦怠量表(MBI)”组成的问卷。问卷通过互联网发送到医生的联系电话。通过土耳其胸科协会和其他专业协会的交流小组、卫生机构的交流小组以及个人通信,向目标人群提供了服务。倦怠以情绪耗竭(EE)、人格解体(DP)和成就感缺乏(LA)三个分量表的得分来评估。结果:参与调查的1177名医生中,有893名医生完整回答了调查。女性占56.70% (n = 506),平均年龄38.63(±11.65)岁。住院医师占41% (n = 366),专科医师占31% (n = 277)。86% (n = 768)的医生难以获得个人防护装备(PPE)。结果表明,893名医生中有81.7% (n = 730)在大流行病房(门诊、急诊、住院、重症监护室)积极工作,这些医生的职业倦怠率明显较高(P < 0.01)。经回归分析排除其他混杂因素后,其Maslach总分和EE得分均显著偏高(P = .001)。结论:在大流行单位工作和难以获得个人防护装备被确定为职业倦怠最重要的危险因素。因此,我们可以说,使用个人防护用品,在管理人员的谨慎和支持下,可以预防医生的职业倦怠。
{"title":"Facing the Pandemic: Burnout in Physicians in Turkey.","authors":"Şengül Tarhan,&nbsp;Gökçen Ömeroğlu Şimşek,&nbsp;Neşe Direk Tecirli,&nbsp;Eyup Sabri Uçan,&nbsp;Merve Atik,&nbsp;Bahriye Oya İtil,&nbsp;Oğuz Kılınç","doi":"10.5152/TurkThoracJ.2021.20240","DOIUrl":"https://doi.org/10.5152/TurkThoracJ.2021.20240","url":null,"abstract":"<p><strong>Objective: </strong>During the COVID-19 pandemic, physicians have been working for long hours, with the fear of contracting the disease and infecting their families. Therefore, there are great concerns about the mental health of physicians. In this research, we aimed to reveal the factors that affect the burnout among physicians working during the pandemic.</p><p><strong>Material and methods: </strong>This is a cross-sectional study involving physicians working during the pandemic in health institutions that admit COVID-19 patients. A questionnaire form consisting of the \"Sociodemographic Data Form\" and the \"Maslach Burnout Inventory (MBI)\" was used. The questionnaire was sent to the contact numbers of physicians via the internet. The target population was reached through the communication groups of the Turkish Thoracic Society and other professional associations, the communication groups of health institutions, and also through personal correspondence. Burnout was evaluated with the scores of each participant from the 3 subscales of Emotional Exhaustion (EE), Depersonalization (DP), and Lack of Accomplishment (LA).</p><p><strong>Results: </strong>Of the 1177 physicians who participated in the survey, 893 answered the survey completely. Females comprised 56.70% (n = 506) of the respondents, and the mean age was 38.63 (±11.65). The residents (41%, n = 366) and specialists (31%, n = 277) made up the majority of the physicians. Eighty-six percent (n = 768) of the physicians had difficulty in obtaining personal protective equipment (PPE). It was determined that 81.7% (n = 730) of the 893 physicians were actively working in pandemic units (outpatient clinics, emergencies, inpatient clinics, intensive care units), and burnout was significantly higher in these physicians (P < .01). After excluding other confounding factors by regression analysis, their Maslach total scores and EE scores were found to be significantly high (P = .001).</p><p><strong>Conclusion: </strong>Working in pandemic units and facing difficulty in accessing PPE are identified as the most important risk factors for burnout. Hence, we can say that working with PPE, and with the managers' discretion and support, the physicians' burnout can be prevented.</p>","PeriodicalId":37452,"journal":{"name":"Turkish Thoracic Journal","volume":"22 6","pages":"439-445"},"PeriodicalIF":0.9,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975354/pdf/ttj-22-6-439.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39758459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Household Air Pollution and Respiratory Symptoms of Women and Children in a Suburban Community in Nigeria. 尼日利亚郊区社区家庭空气污染与妇女和儿童呼吸道症状
IF 0.9 Q4 RESPIRATORY SYSTEM Pub Date : 2021-11-01 DOI: 10.5152/TurkThoracJ.2021.21013
Adesuwa Queen Aigbokhaode, Alphonsus Rukevwe Isara

Objective: Globally, the morbidity and mortality caused by exposure to household air pollution from the use of solid fuels remain a significant public health burden. This study assessed the levels of PM2.5 in households using clean and unclean fuels and their associations with the respiratory health of women and children.

Material and methods: Daytime PM2.5 sampling was done in 62 households (31 in each group) in Isiohor, a suburban community in southern Nigeria using Casella CEL-712 Microdust Pro Real-time Dust Monitor. Validated American Thoracic Society questionnaire was used to assess respiratory symptoms.

Results: PM2.5 levels exceeded World Health Organization-recommended limits in most households. The median (range) concentration of PM2.5 was lower in households using clean fuels (26 (14 to 358) μg/m3) than those using unclean fuels (29 (14 to 650) μg/m3). This difference was not statistically significant (P = .272). At least 1 respiratory symptom was reported by women (25.8% vs. 22.6%) and children (64.5% vs. 77.4%) in household using clean and unclean fuels, respectively. The most commonly reported respiratory symptoms were being woken up by an attack of cough (41.9% vs. 51.6% ) and cough first thing in the morning (16.1% vs 38.7%) for clean and unclean fuels, respectively (P = .046). More children in household using unclean fuel missed school for up to a week because of respiratory illness when compared to those in households using clean fuel, 61.3% vs. 29.0% (P = .011). In the sample as a whole, burning of candles in the house (22.6%) was associated with respiratory symptoms (Adjusted Odds Ratio = 14.81, 95% CI 1.79 to 122.51) among the women.

Conclusion: The use of unclean fuel was associated with higher levels of PM2.5. The household air pollution resulting from the use of unclean fuels and activities like burning of candles in the home may compromise the respiratory health of women and children.

目标:在全球范围内,暴露于使用固体燃料造成的家庭空气污染造成的发病率和死亡率仍然是一个重大的公共卫生负担。这项研究评估了使用清洁和不清洁燃料的家庭中PM2.5的水平,以及它们与妇女和儿童呼吸系统健康的关系。材料和方法:使用Casella CEL-712 Microdust Pro实时粉尘监测仪,对尼日利亚南部郊区社区Isiohor的62户家庭(每组31户)进行了日间PM2.5采样。使用经过验证的美国胸科学会问卷评估呼吸道症状。结果:大多数家庭的PM2.5水平超过了世界卫生组织(World Health organization)建议的限值。使用清洁燃料的家庭PM2.5浓度中位数(范围)(26(14至358)μg/m3)低于使用不清洁燃料的家庭(29(14至650)μg/m3)。差异无统计学意义(P = 0.272)。在使用清洁燃料和不清洁燃料的家庭中,妇女(25.8%对22.6%)和儿童(64.5%对77.4%)分别报告了至少1种呼吸道症状。最常见的呼吸道症状分别是因咳嗽发作而醒来(41.9%对51.6%),以及在使用清洁燃料和不清洁燃料时,早上第一件事就是咳嗽(16.1%对38.7%)(P = 0.046)。与使用清洁燃料的家庭相比,使用不清洁燃料的家庭中有更多的儿童因呼吸道疾病缺课长达一周,分别为61.3%和29.0% (P = 0.011)。在整个样本中,在家中燃烧蜡烛(22.6%)与女性呼吸道症状相关(调整优势比= 14.81,95% CI 1.79至122.51)。结论:不清洁燃料的使用与PM2.5水平升高有关。使用不洁净燃料和在家中燃烧蜡烛等活动造成的室内空气污染可能损害妇女和儿童的呼吸系统健康。
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引用次数: 2
The Effectiveness of a Smoking Cessation Initiative Among Employees in a Textile Factory. 某纺织厂员工戒烟倡议的效果。
IF 0.9 Q4 RESPIRATORY SYSTEM Pub Date : 2021-11-01 DOI: 10.5152/TurkThoracJ.2021.20309
Ahmet Ergin, Semiha Balcı, Caner Özdemir, Hüseyin Öztürk, Betül Özdemir, Huriye Uyar, Oğuz Kilinç

Objective: In this study, we aimed to investigate the effectiveness of a smoking cessation initiative for workers who are smokers in a textile factory located in Denizli, Turkey.

Material and methods: This retrospective cohort was conducted by using the occupational health and safety unit records of 821 workers who are smokers. All participants underwent cognitive behavioral therapy, and in case of need, a suitable pharmacological treatment was initiated. The status of smoking cessation was checked at the end of the third month with a carbon monoxide breath monitor. A chi-square test was performed to make comparisons between categorical variables. Logistic regression analysis (backward) was used to evaluate the factors related to the smoking cessation status.

Results: The ratio of participants who gave up smoking was 74.3%, and 63% of them used a pharmaceutical aid to quit smoking. Working in the department of finishing and using a pharmaceutical aid to quit smoking were related to increased success in smoking cessation.

Conclusion: Outcomes of our study emphasize that workplace-based smoking cessation programs may create a huge impact on smoking cessation among workers. Pharmacological aid and cognitive behavioral therapy have been associated with success in quitting smoking.

目的:在本研究中,我们旨在调查戒烟倡议对位于土耳其德尼兹利的一家纺织厂的吸烟工人的有效性。材料和方法:本回顾性队列研究采用职业卫生安全部门记录的821名吸烟工人。所有参与者都接受了认知行为治疗,在需要的情况下,开始了适当的药物治疗。在第三个月结束时用一氧化碳呼吸监测仪检查戒烟状况。采用卡方检验对分类变量进行比较。采用Logistic回归分析(backward)评价与戒烟状况相关的因素。结果:戒烟者的戒烟率为74.3%,其中63%的人使用药物辅助戒烟。在整理部门工作和使用药物辅助戒烟与戒烟成功率增加有关。结论:我们的研究结果强调,以工作场所为基础的戒烟计划可能会对员工的戒烟产生巨大影响。药物辅助和认知行为疗法与成功戒烟有关。
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引用次数: 0
The Evaluation of APAP Titration Results: Good Titration Versus TECSA and Unacceptable Titration. APAP滴定结果的评价:良好的滴定与TECSA和不合格的滴定。
IF 0.9 Q4 RESPIRATORY SYSTEM Pub Date : 2021-11-01 DOI: 10.5152/TurkThoracJ.2021.21058
Sezgi Şahin Duyar, Deniz Çelik, Selma Fırat

Objective: The first choice for treatment in severe and moderate obstructive sleep apnea syndrome (OSAS) is positive airway pressurem (PAP) devices. However, despite proper titration, respiratory events may persist, while central respiratory events may increase or emerge for some patients. The primary aim of this study is to compare the clinical, demographic, and polysomnographic features of patients with different titration results.

Material and methods: The patients who underwent automatic PAP (APAP) titration with the nasal mask in our clinic due to moderate or severe OSAS in 2017 were included in the study. The clinical, demographic, and polysomnographic characteristics of patients with successful (good) titration, "unacceptable" APAP titration, and treatment-emergent central apnea syndrome (TECSA), were recorded retrospectively and evaluated comparatively with statistical methods.

Results: Out of 942 titration tests with APAP, 37 patients were diagnosed as TECSA (3.9%), while unacceptable (unsuccessful) titrationresults were seen only in 20 patients (2.1%). For the successful titration group, 44 consecutive patients were recruited. In the TECSA group, the central apnea index and minimum SpO2 were higher during the diagnostic polysomnography (PSG). In the unacceptable titration group, the baseline minimum SpO2 was lower. The lower sleep efficiency, lower stage N3 sleep, and longer rapid eye movement (REM) and sleep latencies were observed in the TECSA group during the titration test. The diagnostic accuracy of PAP device recordings was found to be moderate (kappa value: 0.533).

Conclusion: The baseline polysomnographic features, including higher central apnea index and minimum SpO2, may raise suspicion for titration failures for which a laboratory-based titration can be scheduled.

目的:重度和中度阻塞性睡眠呼吸暂停综合征(OSAS)的首选治疗方法是气道正压通气(PAP)设备。然而,尽管适当的滴定,呼吸事件可能持续存在,而中枢呼吸事件可能增加或出现一些患者。本研究的主要目的是比较不同滴定结果患者的临床、人口学和多导睡眠图特征。材料与方法:选取2017年我院因中重度OSAS患者经鼻罩自动PAP (APAP)滴定的患者作为研究对象。回顾性记录APAP滴定成功(良好)、“不可接受”和治疗后出现的中枢性呼吸暂停综合征(TECSA)患者的临床、人口学和多导睡眠图特征,并用统计学方法进行比较评价。结果:在942例APAP滴定试验中,37例患者被诊断为TECSA(3.9%),而不可接受(不成功)的滴定结果仅在20例患者中出现(2.1%)。为成功滴入组,连续招募44例患者。在诊断性多导睡眠图(PSG)中,TECSA组的中枢呼吸暂停指数和最低SpO2较高。在不可接受滴定组中,基线最低SpO2较低。滴定试验中,TECSA组睡眠效率较低,N3期睡眠时间较短,快速眼动(REM)和睡眠潜伏期较长。PAP器械记录的诊断准确性为中等(kappa值:0.533)。结论:基线多导睡眠图特征,包括较高的中枢呼吸暂停指数和最低的SpO2,可能会引起滴定失败的怀疑,因此可以安排基于实验室的滴定。
{"title":"The Evaluation of APAP Titration Results: Good Titration Versus TECSA and Unacceptable Titration.","authors":"Sezgi Şahin Duyar,&nbsp;Deniz Çelik,&nbsp;Selma Fırat","doi":"10.5152/TurkThoracJ.2021.21058","DOIUrl":"https://doi.org/10.5152/TurkThoracJ.2021.21058","url":null,"abstract":"<p><strong>Objective: </strong>The first choice for treatment in severe and moderate obstructive sleep apnea syndrome (OSAS) is positive airway pressurem (PAP) devices. However, despite proper titration, respiratory events may persist, while central respiratory events may increase or emerge for some patients. The primary aim of this study is to compare the clinical, demographic, and polysomnographic features of patients with different titration results.</p><p><strong>Material and methods: </strong>The patients who underwent automatic PAP (APAP) titration with the nasal mask in our clinic due to moderate or severe OSAS in 2017 were included in the study. The clinical, demographic, and polysomnographic characteristics of patients with successful (good) titration, \"unacceptable\" APAP titration, and treatment-emergent central apnea syndrome (TECSA), were recorded retrospectively and evaluated comparatively with statistical methods.</p><p><strong>Results: </strong>Out of 942 titration tests with APAP, 37 patients were diagnosed as TECSA (3.9%), while unacceptable (unsuccessful) titrationresults were seen only in 20 patients (2.1%). For the successful titration group, 44 consecutive patients were recruited. In the TECSA group, the central apnea index and minimum SpO2 were higher during the diagnostic polysomnography (PSG). In the unacceptable titration group, the baseline minimum SpO2 was lower. The lower sleep efficiency, lower stage N3 sleep, and longer rapid eye movement (REM) and sleep latencies were observed in the TECSA group during the titration test. The diagnostic accuracy of PAP device recordings was found to be moderate (kappa value: 0.533).</p><p><strong>Conclusion: </strong>The baseline polysomnographic features, including higher central apnea index and minimum SpO2, may raise suspicion for titration failures for which a laboratory-based titration can be scheduled.</p>","PeriodicalId":37452,"journal":{"name":"Turkish Thoracic Journal","volume":"22 6","pages":"450-458"},"PeriodicalIF":0.9,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975285/pdf/ttj-22-6-450.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39758461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COVID-19, Severe Asthma and Omalizumab Therapy: A Case-Based Inquiry into Associations, Management, and the Possibility of a Better Outcome. COVID-19、严重哮喘和奥玛单抗治疗:基于病例的关联、管理和更好结果可能性调查
IF 0.9 Q4 RESPIRATORY SYSTEM Pub Date : 2021-11-01 DOI: 10.5152/TurkThoracJ.2021.20329
Sadi Can Sönmez, Zeynep Büşra Kısakürek, Ayse Bilge Ozturk, Süda Tekin
Recent developments in research have put forward claims on the protective effect of allergic diseases-especially allergic airway inflammation including allergic asthma-against the COVID-19 pandemic. This was first suggested by the underrepresentation of asthma patients in some cohorts and was later investigated by angiotensin-converting enzyme II (ACEII) receptor expression studies. Controversial data on this matter persists and continue to be a challenge for clinicians when it comes to managing allergic diseases during the pandemic. We present in this study a thorough review of related findings so far and our own experience with 2 severe asthma patients who presented with atypical symptoms. Interestingly, both patients were administered anti-IgE therapy prior to the initial positive polymerase chain reaction (PCR) results for COVID-19 and showed no symptoms of severe respiratory disease during the infection unlike what we know from other viral respiratory illnesses. Stemming from that, we wanted to combine the perspectives of allergists and infectious disease specialists to address certain concerns in the management of allergic diseases, such as biologicals, in the light of current guidelines. We have also pointed out certain gaps in clinical and molecular level research, such as the lack of phenotypicalsubgroup analysis among ill asthma patients and the lack of data concerning the molecular effects of biologicals on viral infection.
最近的研究进展表明,过敏性疾病,特别是过敏性气道炎症,包括过敏性哮喘,对COVID-19大流行具有保护作用。这首先是由哮喘患者在一些队列中的代表性不足提出的,后来通过血管紧张素转换酶II (ACEII)受体表达研究进行了调查。关于这一问题的有争议的数据仍然存在,并继续成为临床医生在大流行期间管理过敏性疾病时面临的挑战。在这项研究中,我们对迄今为止的相关发现和我们自己对2例表现出非典型症状的严重哮喘患者的经验进行了全面的回顾。有趣的是,这两名患者在COVID-19聚合酶链反应(PCR)最初呈阳性之前都接受了抗ige治疗,并且在感染期间没有表现出严重呼吸道疾病的症状,这与我们从其他病毒性呼吸道疾病中所知道的不同。基于此,我们希望结合过敏症专家和传染病专家的观点,根据当前的指导方针,解决过敏疾病(如生物制剂)管理中的某些问题。我们还指出了临床和分子水平研究的某些空白,例如缺乏哮喘患者的表型亚组分析以及缺乏生物制剂对病毒感染的分子作用的数据。
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引用次数: 0
Call for Emergency Action to Limit Global Temperature Increases, Restore Biodiversity, and Protect Health. 呼吁采取紧急行动,限制全球气温上升,恢复生物多样性,保护健康。
IF 0.9 Q4 RESPIRATORY SYSTEM Pub Date : 2021-09-01 DOI: 10.5152/TurkThoracJ.2021.21060921
Lukoye Atwoli, Abdullah H Baqui, Thomas Benfield, Raffaella Bosurgi, Fiona Godlee, Stephen Hancocks, Richard Horton, Laurie Laybourn-Langton, Carlos Augusto Monteiro, Ian Norman, Kirsten Patrick, Nigel Praities, Marcel G M Olde Rikkert, Eric J Rubin, Peush Sahni, Richard Smith, Nicholas J Talley, Sue Turale, Damián Vázquez
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引用次数: 0
Isolated Pulmonary Cysticercosis Presenting as Mass Lesion. 孤立性肺囊虫病表现为肿块性病变。
IF 0.9 Q4 RESPIRATORY SYSTEM Pub Date : 2021-09-01 DOI: 10.5152/TurkThoracJ.2021.0027
Parul Mrigpuri, Vatsal Bhushan Gupta, Balakrishnan Menon, Sonam Spalgais, Raj Kumar

We report a case of pulmonary cysticercosis manifesting as a mass lesion. Cysticercosis confined to lungs is a rare manifestation of human cysticercosis. The disease mainly affects the central nervous system, skeletal muscles, and eyes. Pulmonary involvement is rare and usually presents as bilateral pulmonary nodules. The diagnosis was made based on positive enzyme-linked immunosorbent assay (ELISA) for anticysticercal antibodies, and the patient was started on antiparasitic therapy along with steroids. Symptomatic and radiological improvement was seen. There is no previous case report of isolated pulmonary cysticercosis presenting as mass lesion.

我们报告一例肺囊虫病表现为肿块病变。局限于肺部的囊虫病是一种罕见的人类囊虫病表现。该病主要影响中枢神经系统、骨骼肌和眼睛。肺部受累是罕见的,通常表现为双侧肺结节。根据抗囊虫抗体酶联免疫吸附试验(ELISA)阳性诊断,患者开始接受抗寄生虫治疗和类固醇治疗。症状和放射学均有改善。以往未见孤立性肺囊虫病表现为肿块性病变的病例报告。
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引用次数: 0
期刊
Turkish Thoracic Journal
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