Pub Date : 2021-02-16DOI: 10.20418/jrcd.v0i0.409.g327
M. Prabhu, Jagadish Madireddy, Ranjan Shetty, Weena Stanley
Background: Acute coronary syndromes (ACSs) are the primary cause of mortality worldwide. The aim of the study was to assess the as‑sociations of serum fibrinogen and plasma D‑dimer levels with angiographic severity of atherosclerotic lesions as well as the presence of in‑hospital complications and complications at 30‑day follow‑up in patients with ACS. Methods: This was a prospective study including 107 patients with ACS. Severity of CAD was assessed by the Gensini score. Correlations of D‑dimer and fibrinogen levels with complica‑tions such as heart failure, arrhythmia, recurrent angina, and cardiac death were assessed using the Pearson correlation coefficient and the receiver operating characteristic curve analysis. Results: The mean age of patients was 61±10.9 years. Mean serum fibrinogen levels were higher in individuals with severe left ventricular (LV) dysfunction than in those with moderate and mild LV dysfunction (444 mg/dl, 404 mg/dl, and 330 mg/dl, respectively). Similarly, the mean plasma D‑dimer level was higher in individuals with severe ACS (1.03 μg/ml) than in those with moderate (1.88 μg/ml) and mild ACS (3.5 μg/ml). Conclusion: Our study revealed that patients with higher serum fibrinogen levels tend to have more severe ACS, greater LV dysfunction, and a higher rate of complications. Therapies aimed at reducing fibrinogen levels might help reduce mortality and morbidity in patients with ACS.
{"title":"Association of fibrinogen and D‑dimer levels with severity of acute coronary syndromes","authors":"M. Prabhu, Jagadish Madireddy, Ranjan Shetty, Weena Stanley","doi":"10.20418/jrcd.v0i0.409.g327","DOIUrl":"https://doi.org/10.20418/jrcd.v0i0.409.g327","url":null,"abstract":"Background: Acute coronary syndromes (ACSs) are the primary cause of mortality worldwide. The aim of the study was to assess the as‑sociations of serum fibrinogen and plasma D‑dimer levels with angiographic severity of atherosclerotic lesions as well as the presence of in‑hospital complications and complications at 30‑day follow‑up in patients with ACS. Methods: This was a prospective study including 107 patients with ACS. Severity of CAD was assessed by the Gensini score. Correlations of D‑dimer and fibrinogen levels with complica‑tions such as heart failure, arrhythmia, recurrent angina, and cardiac death were assessed using the Pearson correlation coefficient and the receiver operating characteristic curve analysis. Results: The mean age of patients was 61±10.9 years. Mean serum fibrinogen levels were higher in individuals with severe left ventricular (LV) dysfunction than in those with moderate and mild LV dysfunction (444 mg/dl, 404 mg/dl, and 330 mg/dl, respectively). Similarly, the mean plasma D‑dimer level was higher in individuals with severe ACS (1.03 μg/ml) than in those with moderate (1.88 μg/ml) and mild ACS (3.5 μg/ml). Conclusion: Our study revealed that patients with higher serum fibrinogen levels tend to have more severe ACS, greater LV dysfunction, and a higher rate of complications. Therapies aimed at reducing fibrinogen levels might help reduce mortality and morbidity in patients with ACS.","PeriodicalId":37488,"journal":{"name":"Journal of Rare Cardiovascular Diseases","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83529249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-12-02DOI: 10.20418/JRCD.V4I4.418.G322
P. Podolec
{"title":"Journal of Rare Cardiovascular Diseases in EuroPub database","authors":"P. Podolec","doi":"10.20418/JRCD.V4I4.418.G322","DOIUrl":"https://doi.org/10.20418/JRCD.V4I4.418.G322","url":null,"abstract":"","PeriodicalId":37488,"journal":{"name":"Journal of Rare Cardiovascular Diseases","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84814768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-09-02DOI: 10.20418/JRCD.VOL4NO3.396
O. Kalashnykova, L. Vasilyeva, Alina Vasilevna Khomich
Endothelin receptor antagonist (ERA) therapy‐induced increase in liver transaminases in patients with pulmonary arterial hypertension (PAH) is an adverse effect of bosentan which is not fully understood. A 62‐year‐old female with a 1.5‐year history of progressively worsening dyspnoea was diagnosed with idiopathic PAH (IPAH). After 2 months of PAH treatment with bosentan, levels of liver transaminases were elevated and autoimmune hepatitis was diagnosed. This clinical case demonstrates the challenge of diagnosing autoimmune hepatitis induced by ERA therapy in clinical practice. A thorough understanding of the pathogenesis and clinical presentation of autoimmune hepatitis, as well as the possibility to perform specific investigations with multiple serological markers are crucial for establishing the correct diagnosis. JRCD 2019; 4 (4): 101-105.
{"title":"Autoimmune hepatitis induced by bosentan in a patient with pulmonary arterial hypertension (RCD code: II‐1A.1; VIII)","authors":"O. Kalashnykova, L. Vasilyeva, Alina Vasilevna Khomich","doi":"10.20418/JRCD.VOL4NO3.396","DOIUrl":"https://doi.org/10.20418/JRCD.VOL4NO3.396","url":null,"abstract":"Endothelin receptor antagonist (ERA) therapy‐induced increase in liver transaminases in patients with pulmonary arterial hypertension (PAH) is an adverse effect of bosentan which is not fully understood. A 62‐year‐old female with a 1.5‐year history of progressively worsening dyspnoea was diagnosed with idiopathic PAH (IPAH). After 2 months of PAH treatment with bosentan, levels of liver transaminases were elevated and autoimmune hepatitis was diagnosed. This clinical case demonstrates the challenge of diagnosing autoimmune hepatitis induced by ERA therapy in clinical practice. A thorough understanding of the pathogenesis and clinical presentation of autoimmune hepatitis, as well as the possibility to perform specific investigations with multiple serological markers are crucial for establishing the correct diagnosis. JRCD 2019; 4 (4): 101-105.","PeriodicalId":37488,"journal":{"name":"Journal of Rare Cardiovascular Diseases","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78958466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-09-02DOI: 10.20418/JRCD.VOL4NO3.386
D. B. Tadesse, Gebre Yitayih, Weyzer Tilahun, Gebreamlak Gebremedhn, Kiros Belay, B. Hailu, Yohannes Ashebir, Gebre Teklemariam Demoz, Mulugeta Molla
Objective: Although hypertension is the leading cause of cardiovascular complications, time to develop cardiovascular complications among hypertensive patients has not been adequately investigated in Ethiopia. Therefore, the aim of this study was to assess time to develop cardiovascular complications and its predictors among adult hypertensive patients at the Ayder Comprehensive Specialized Hospital, Ethiopia. Result: A total of 578 hypertensive patients from the Cardiology Department were included in the study and followed for a total of 60 months (median 28 months). Half of the participants (290, 50.2%) were females. The median age of subjects was 54 years. Out of the 578 hypertensive patients who were analysed, 25.4% of them developed a cardiovascular complication. The incidence rate was 8.25 per 1000 persons per month. Significant predictors in the development of cardiovascular complications among hypertensive patients were age [AHR = 1.03 (95% CI=1.016, 1.046)], baseline cardiovascular complications [AHR=3.03 (95% CI=2.009, 4.870)], proteinuria [AHR=3.9 (95% CI=1.3, 11.68)], baseline systolic blood pressure [AHR =1.01 (95% CI=1.003, 2.012)], and baseline diastolic blood pres‐sure [AHR = 1.013 (95% CI=1.005, 2.021)]. JRCD 2019; 4 (4): 96-100.
{"title":"Survival analysis of time to develop cardiovascular complications and its predictors among hypertensive patients treated in the Ayder Comprehensive Specialized Hospital, Ethiopia: a retrospective cohort study (RCD code: VIII)","authors":"D. B. Tadesse, Gebre Yitayih, Weyzer Tilahun, Gebreamlak Gebremedhn, Kiros Belay, B. Hailu, Yohannes Ashebir, Gebre Teklemariam Demoz, Mulugeta Molla","doi":"10.20418/JRCD.VOL4NO3.386","DOIUrl":"https://doi.org/10.20418/JRCD.VOL4NO3.386","url":null,"abstract":"Objective: Although hypertension is the leading cause of cardiovascular complications, time to develop cardiovascular complications among hypertensive patients has not been adequately investigated in Ethiopia. Therefore, the aim of this study was to assess time to develop cardiovascular complications and its predictors among adult hypertensive patients at the Ayder Comprehensive Specialized Hospital, Ethiopia. Result: A total of 578 hypertensive patients from the Cardiology Department were included in the study and followed for a total of 60 months (median 28 months). Half of the participants (290, 50.2%) were females. The median age of subjects was 54 years. Out of the 578 hypertensive patients who were analysed, 25.4% of them developed a cardiovascular complication. The incidence rate was 8.25 per 1000 persons per month. Significant predictors in the development of cardiovascular complications among hypertensive patients were age [AHR = 1.03 (95% CI=1.016, 1.046)], baseline cardiovascular complications [AHR=3.03 (95% CI=2.009, 4.870)], proteinuria [AHR=3.9 (95% CI=1.3, 11.68)], baseline systolic blood pressure [AHR =1.01 (95% CI=1.003, 2.012)], and baseline diastolic blood pres‐sure [AHR = 1.013 (95% CI=1.005, 2.021)]. JRCD 2019; 4 (4): 96-100.","PeriodicalId":37488,"journal":{"name":"Journal of Rare Cardiovascular Diseases","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75013920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-09-02DOI: 10.20418/JRCD.VOL4NO3.398
K. Holcman, M. Kostkiewicz, P. Podolec, P. Rubis
{"title":"Amyloid cardiomyopathy – the true burden, current approach to diagnosis and treatment (RCD code III‐3A.1, III‐3A.2)","authors":"K. Holcman, M. Kostkiewicz, P. Podolec, P. Rubis","doi":"10.20418/JRCD.VOL4NO3.398","DOIUrl":"https://doi.org/10.20418/JRCD.VOL4NO3.398","url":null,"abstract":"","PeriodicalId":37488,"journal":{"name":"Journal of Rare Cardiovascular Diseases","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87829235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-09-02DOI: 10.20418/JRCD.VOL4NO3.390
S. Tatari
Unicuspid aortic valve is a rare congenital abnormality with a prevalence of 0.02% in the adult population. Left ventricular noncompaction is another congenital anomaly with an incidence of 0.05%. Unicuspid aortic valve with severe aortic regurgitation and left ventricular noncompaction was found in a 15-year-old deaf male patient who presented with shortness of breath, orthopnoea and intermittent palpitations. JRCD 2019; 4 (4): 106–108.
{"title":"An Extremely Rare Congenital Association: Uni- cuspid Aortic Valve with Left Ventricular Noncom- paction (RCD code: III-5A.1.o)","authors":"S. Tatari","doi":"10.20418/JRCD.VOL4NO3.390","DOIUrl":"https://doi.org/10.20418/JRCD.VOL4NO3.390","url":null,"abstract":"Unicuspid aortic valve is a rare congenital abnormality with a prevalence of 0.02% in the adult population. Left ventricular noncompaction is another congenital anomaly with an incidence of 0.05%. Unicuspid aortic valve with severe aortic regurgitation and left ventricular noncompaction was found in a 15-year-old deaf male patient who presented with shortness of breath, orthopnoea and intermittent palpitations. JRCD 2019; 4 (4): 106–108.","PeriodicalId":37488,"journal":{"name":"Journal of Rare Cardiovascular Diseases","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73241685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-31DOI: 10.20418/JRCD.VOL4NO3.357
Jacek Kuźma, P. Weryński, P. Skorek, M. Rączka, Katarzyna Konarska
We present the case of a boy with pulmonary atresia (PA), intact ventricular septum (IVS), and a coronary fistula between the right ventricle (RV) and a single left coronary artery (SLCA). In the newborn period, the child was operated on using a right Blalock–Taussing shunt (RBTS). At the age of 6 months, he was admitted to the department of Paediatric Cardiology due to hypoxaemia and cardiac catheterisation was performed before qualification for cardiac surgery. During haemodynamic evaluation of the patient, we conducted the balloon occlusion test of the coronary fistula and demonstrated that coronary circulation depends on the wide fistula and high pres‐ sure in the RV. We decided not to perform embolisation of the fistula and qualified the child for bidirectional Glenn palliation without RV decompression. The balloon occlusion test in patients with coronary fistulas plays a critical role and its result can be crucial for further management of the patient. JRCD 2019; 4 (3): 55-58.
{"title":"Critical value of the balloon occlusion test of a coronary fistula in a patient with pulmonary atresia and intact ventricular septum (RCD code: I 1C.4; II 2A.1)","authors":"Jacek Kuźma, P. Weryński, P. Skorek, M. Rączka, Katarzyna Konarska","doi":"10.20418/JRCD.VOL4NO3.357","DOIUrl":"https://doi.org/10.20418/JRCD.VOL4NO3.357","url":null,"abstract":"We present the case of a boy with pulmonary atresia (PA), intact ventricular septum (IVS), and a coronary fistula between the right ventricle (RV) and a single left coronary artery (SLCA). In the newborn period, the child was operated on using a right Blalock–Taussing shunt (RBTS). At the age of 6 months, he was admitted to the department of Paediatric Cardiology due to hypoxaemia and cardiac catheterisation was performed before qualification for cardiac surgery. During haemodynamic evaluation of the patient, we conducted the balloon occlusion test of the coronary fistula and demonstrated that coronary circulation depends on the wide fistula and high pres‐ sure in the RV. We decided not to perform embolisation of the fistula and qualified the child for bidirectional Glenn palliation without RV decompression. The balloon occlusion test in patients with coronary fistulas plays a critical role and its result can be crucial for further management of the patient. JRCD 2019; 4 (3): 55-58.","PeriodicalId":37488,"journal":{"name":"Journal of Rare Cardiovascular Diseases","volume":"6 1","pages":"55-58"},"PeriodicalIF":0.0,"publicationDate":"2020-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81701151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-31DOI: 10.20418/JRCD.VOL4NO3.387
U. Chernyaha-Royko, M. Sorokivskyy, A. Aker, B. Kravchuk, V. Kuts, O. Zharinov
Dual atrioventricular nodal non‐reentrant tachycardia (DAVNNT) is a rarely diagnosed, sustained supraventricular arrhythmia. We report the case of a 39‐year‐old female with drug‐resistant, irregular, narrow QRS complex tachycardia which gradually led to tachycardia‐induced cardiomyopathy. Previously, this arrhythmia was recognized as atrial fibrillation, with several unsuccessful attempts at pulmonary vein isolation. Only after the correct diagnosis of DAVNNT was established, successful radiofrequency ablation of the slow pathway in the atrioventricular node was performed, with complete cure of the arrhythmia. JRCD 2019; 4 (3): 59-62.
{"title":"Tachycardia induced cardiomyopathy due to dual atrioventricular nodal non reentrant tachycardia (RCDD code: VI 1A 9)","authors":"U. Chernyaha-Royko, M. Sorokivskyy, A. Aker, B. Kravchuk, V. Kuts, O. Zharinov","doi":"10.20418/JRCD.VOL4NO3.387","DOIUrl":"https://doi.org/10.20418/JRCD.VOL4NO3.387","url":null,"abstract":"Dual atrioventricular nodal non‐reentrant tachycardia (DAVNNT) is a rarely diagnosed, sustained supraventricular arrhythmia. We report the case of a 39‐year‐old female with drug‐resistant, irregular, narrow QRS complex tachycardia which gradually led to tachycardia‐induced cardiomyopathy. Previously, this arrhythmia was recognized as atrial fibrillation, with several unsuccessful attempts at pulmonary vein isolation. Only after the correct diagnosis of DAVNNT was established, successful radiofrequency ablation of the slow pathway in the atrioventricular node was performed, with complete cure of the arrhythmia. JRCD 2019; 4 (3): 59-62.","PeriodicalId":37488,"journal":{"name":"Journal of Rare Cardiovascular Diseases","volume":"1 1","pages":"59-62"},"PeriodicalIF":0.0,"publicationDate":"2020-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83062629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-31DOI: 10.20418/JRCD.VOL4NO3.384
J. Chmiel, M. K. Książek, Grażyna Świtacz, J. Dradrach, Iwaszczuk, Leszek Drabik, P. Podolec, P. Musialek
Introduction Coronary artery fistula (CAF) is a rare anomaly, mostly congenital, defined as an abnormal direct connection between one of the coronary arteries and a heart chamber or major vessel. In case of coronary steal, CAF may manifest with symptoms of stable coro‐ nary disease (CAD). Methods We investigated medical records of all adult patients who underwent coronary angiography (CAG) from 1 July 2009 to 30 June 2019. Patients with solitary CAF were selected. Coronary artery‐ventricular multiple microfistulas (MMFs) were recorded but were no object for further analysis. The CAFs were grouped depending on the origin and termination. Clinical symptoms, comorbidities and past medical history were analyzed. Results 26 solitary CAFs were found in 22 (0.17%) and 20 MMFs in 16 (0.13%) out of 12,757 patients who underwent CAG for any reason in that period. Indication for CAG varied among study group. Left coronary artery (LCA) gave origin to majority (57.69%) of fistulas. Pulmonary artery (PA) was the most common drainage site (69.23%). 17 patients had HA, 15 suffered from chest pain or dyspnoea, 13 had dyslipidemia, and half had CAD. Conclusion The incidence of solitary CAF in the sample of all‐comer population of Polish patients undergoing CAG was 0.17%. LCA was the most common artery of origin and PA was the most frequent drainage site. The indication for CAG varied among patients. Majority of patients suffered from chest pain or dyspnea, had HA, dyslipidemia, and half had CAD. Moreover, the incidence of MMF was 0.13%. JRCD 2019; 4 (3): 42-46.
{"title":"Prevalence and characteristics of patients with solitary coronary artery fistulas in 12,757 all comer adult patients undergoing coronary angiography (RCD code: I 1C.4)","authors":"J. Chmiel, M. K. Książek, Grażyna Świtacz, J. Dradrach, Iwaszczuk, Leszek Drabik, P. Podolec, P. Musialek","doi":"10.20418/JRCD.VOL4NO3.384","DOIUrl":"https://doi.org/10.20418/JRCD.VOL4NO3.384","url":null,"abstract":"Introduction Coronary artery fistula (CAF) is a rare anomaly, mostly congenital, defined as an abnormal direct connection between one of the coronary arteries and a heart chamber or major vessel. In case of coronary steal, CAF may manifest with symptoms of stable coro‐ nary disease (CAD). Methods We investigated medical records of all adult patients who underwent coronary angiography (CAG) from 1 July 2009 to 30 June 2019. Patients with solitary CAF were selected. Coronary artery‐ventricular multiple microfistulas (MMFs) were recorded but were no object for further analysis. The CAFs were grouped depending on the origin and termination. Clinical symptoms, comorbidities and past medical history were analyzed. Results 26 solitary CAFs were found in 22 (0.17%) and 20 MMFs in 16 (0.13%) out of 12,757 patients who underwent CAG for any reason in that period. Indication for CAG varied among study group. Left coronary artery (LCA) gave origin to majority (57.69%) of fistulas. Pulmonary artery (PA) was the most common drainage site (69.23%). 17 patients had HA, 15 suffered from chest pain or dyspnoea, 13 had dyslipidemia, and half had CAD. Conclusion The incidence of solitary CAF in the sample of all‐comer population of Polish patients undergoing CAG was 0.17%. LCA was the most common artery of origin and PA was the most frequent drainage site. The indication for CAG varied among patients. Majority of patients suffered from chest pain or dyspnea, had HA, dyslipidemia, and half had CAD. Moreover, the incidence of MMF was 0.13%. JRCD 2019; 4 (3): 42-46.","PeriodicalId":37488,"journal":{"name":"Journal of Rare Cardiovascular Diseases","volume":"13 4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76564034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-29DOI: 10.20418/JRCD.VOL4NO3.389
Maryla Mianowana, Łukasz Siudak, P. Blaszczak
Pulmonary arterial hypertension is a rare disease of pulmonary circulation with poor prognosis if left untreated or diagnosed with delay. Active screening for the disease is not effective in the general population. However, in populations at increased risk for pulmonary arterial hypertension, all efforts should be taken to establish an early diagnosis. Here, we present 2 cases of late diagnosis. The first patient presented with a clear clinical picture, while the second case describes a patient in the at‐risk population who received treatment too late to obtain satisfactory results. We discuss the pitfalls which led to delayed diagnosis that finally resulted in treatment failure. JRCD 2019; 4 (3): 47-50.
{"title":"Early diagnosis is crucial for successful treatment of pulmonary arterial hypertension: 2 cases of late diagnosis (RCD code: II 1A.1)","authors":"Maryla Mianowana, Łukasz Siudak, P. Blaszczak","doi":"10.20418/JRCD.VOL4NO3.389","DOIUrl":"https://doi.org/10.20418/JRCD.VOL4NO3.389","url":null,"abstract":"Pulmonary arterial hypertension is a rare disease of pulmonary circulation with poor prognosis if left untreated or diagnosed with delay. Active screening for the disease is not effective in the general population. However, in populations at increased risk for pulmonary arterial hypertension, all efforts should be taken to establish an early diagnosis. Here, we present 2 cases of late diagnosis. The first patient presented with a clear clinical picture, while the second case describes a patient in the at‐risk population who received treatment too late to obtain satisfactory results. We discuss the pitfalls which led to delayed diagnosis that finally resulted in treatment failure. JRCD 2019; 4 (3): 47-50.","PeriodicalId":37488,"journal":{"name":"Journal of Rare Cardiovascular Diseases","volume":"35 1","pages":"47-50"},"PeriodicalIF":0.0,"publicationDate":"2020-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82651804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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