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Differentials of respiratory failure in COVID-19 patients with myasthenia COVID-19合并重症肌无力患者呼吸衰竭的鉴别分析
Pub Date : 1900-01-01 DOI: 10.54660/.ijmrge.2023.4.1.603-604
J. Finsterer, Fulvio A Scorza
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引用次数: 0
The impact of human resource management and educational innovation on employees' organizational commitment: A case study at Saigon International University, Vietnam 人力资源管理与教育创新对员工组织承诺的影响——以越南西贡国际大学为例
Pub Date : 1900-01-01 DOI: 10.54660/.ijmrge.2023.4.2.241-251
Tran Lan Chi, Phuoc Minh Hiep, Vo Thi Thu Hong
Higher education in Vietnam is in a period of autonomy, self-responsibility in all aspects, and human resource management (HRM) to increase commitment to employees' organizations in the context of educational innovation. This has been receiving the attention of the whole community. The results showed that HRM (including attracting, training and developing, maintaining humSan resources) and educational innovation (including decentralization, socialization of education, integration) have a positive influence on both organizational satisfaction and organizational commitment. Satisfaction also has a positive influence on employees' organizational commitment. This result sets the stage for proposing some governance implications to the leadership of Saigon International University (SIU), Vietnam.
越南的高等教育正处于一个自主、各方面自我负责的时期,在教育创新的背景下,人力资源管理(HRM)增加了对员工组织的承诺。这已经引起了整个社会的关注。结果表明,人力资源管理(包括吸引、培训和开发、维护人力资源)和教育创新(包括分权化、教育社会化、整合化)对组织满意度和组织承诺均有正向影响。满意度对员工的组织承诺也有正向影响。这一结果为越南西贡国际大学(SIU)领导层提出一些治理建议奠定了基础。
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引用次数: 0
Distal peripheral nerves may be involved in Parsonage Turner syndrome 远端周围神经可能累及透纳综合征
Pub Date : 1900-01-01 DOI: 10.54660/.ijmrge.2023.4.2.16-17
J. Finsterer, F. Scorza
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引用次数: 0
Method development and validation for the quantitative estimation of Trametinib in API form and marketed tablet dosage form by RP-HPLC 采用反相高效液相色谱法对曲美替尼原料药和市售片剂进行定量评价的方法建立与验证
Pub Date : 1900-01-01 DOI: 10.54660/.ijmrge.2023.4.1.369-374
K. Deepthi, Bommagouni Ramya, J. Priyanka, Lingampally Pranali, Thalla Harisha, Ganta Brundharika
The development of analytical methods is in need for the estimation of Trametinib in pure and different pharmaceutical formulations. A simple, sensitive, rapid, accurate, precise and economic chromatographic method was developed and validated for Trametinib in pure and pharmaceutical formulations. The proposed method was validated according to the International Conference on Harmonization (ICH) guidelines. This separation is performed on Symmetry ODS (C18) RP Column, 250 mm x 4.6 mm, 5µm Column and mobile phase consists of ACN : Methanol: 0.1% OPA in the ratio of 60:30:10v/v/v at flow rate of 1.0ml/min. The wave length (λmax) used for the estimation of Trametinib is 267 nm by chromatographic method. The linearity of the calibration curve was validated by the high values of the correlation coefficient of regression. The percentage of Trametinib recovered was found to be within the limits i.e. 98-102% for Trametinib. LOD and LOQ values for Trametinib were found to be 0.08µg/ml and 0.24µg/ml respectively. The developed methods are simple and suitable for the determination of Trametinib in pure and pharmaceutical preparations.
需要发展分析方法来估计纯制剂和不同制剂中曲美替尼的含量。建立了一种简便、灵敏、快速、准确、精密度高、经济的纯制剂和制剂曲美替尼色谱分析方法。根据国际协调会议(ICH)指南对所提出的方法进行了验证。该分离在对称ODS (C18) RP柱上进行,250 mm × 4.6 mm, 5µm柱,流动相由ACN:甲醇:0.1% OPA组成,比例为60:30:10v/v/v,流速为1.0ml/min。色谱法测定曲美替尼的波长(λmax)为267 nm。回归相关系数较高,验证了标定曲线的线性。曲美替尼的回收率在98 ~ 102%范围内。曲美替尼的LOD和LOQ值分别为0.08µg/ml和0.24µg/ml。该方法简便,适用于纯制剂和制剂中曲美替尼的含量测定。
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引用次数: 0
Borderline personality disorder: Gender bias and diagnostic disparities 边缘型人格障碍:性别偏见和诊断差异
Pub Date : 1900-01-01 DOI: 10.54660/.ijmrge.2023.4.1.296-301
Nicole Gorra
Borderline Personality Disorder (BPD) is a DSM-5 Cluster B mental health condition. One of the lesser understood mental health conditions, BPD is marked by a multi-symptom profile such as high levels of emotional dysregulation, distorted self-image, volatile and unstable relationships, emotional instability, and higher levels of suicidality. Symptoms are often intense and enduring, causing significant chaos and stress in an individual’s life as well as those closest to them. Because there is a significant overlap of symptomology and diagnosis with other psychiatric disorders, BPD was at one time a contested diagnosis, thus research and treatment options remained limited. Currently, BPD is one of the more widely researched conditions, which has informed evidenced-based treatment, however, individuals carrying the diagnosis report difficulty accessing treatment and difficulty feeling understood by mental healthcare providers. The development of BPD remains unclear, although consistent with other mental health conditions there is a genetic constituent, and with BPD in particular a history of trauma. This research manual will explore current evidence-based practices and assessment methods to inform best practices when working with BPD.
边缘型人格障碍(BPD)是DSM-5 B类精神健康状况。BPD是一种鲜为人知的精神健康状况,其特征是多重症状,如高度的情绪失调、扭曲的自我形象、反复无常和不稳定的关系、情绪不稳定和较高的自杀率。症状通常是强烈和持久的,给个人以及最亲近的人的生活造成严重的混乱和压力。由于症状学和诊断与其他精神疾病有很大的重叠,BPD一度是一个有争议的诊断,因此研究和治疗选择仍然有限。目前,BPD是一种被广泛研究的疾病,它为基于证据的治疗提供了信息,然而,患有诊断的个体报告难以获得治疗,难以被精神卫生保健提供者理解。BPD的发展尚不清楚,尽管与其他精神健康状况一致,存在遗传因素,尤其是创伤史。本研究手册将探讨当前基于证据的实践和评估方法,以告知与BPD合作时的最佳实践。
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引用次数: 0
The impact of sodium silicate coatings on the freeze-thaw resistance of ground granulated blast furnace slag mortar 水玻璃涂层对粉状高炉矿渣砂浆抗冻融性能的影响
Pub Date : 1900-01-01 DOI: 10.54660/.ijmrge.2023.4.2.86-91
Mostafa M. Ahmed, Kanako Okazaki, T. Fujii, Toshiki Ayano
The study elucidated how sodium silicate coating halts the deterioration of the mortar samples significantly with the addition of ground granulated blast furnace slag (GGBS) into the binder mass (B), the coated samples exhibited a substantial increment in freeze and thaw resistance compared to non-coated samples. The study included implementing freeze and thaw cycles on mortar samples with 4 different GGBS/B ratios: 0%, 30%, 50%, and 70%. The multiple coatings of sodium silicate were also tested against freeze and thaw cycles (3 and 6 coatings). The cumulative scaling was measured for all mortar samples at 7,14,21,28, and 35 freeze-thaw cycles. The freeze-thaw resistance tests indicated that the mortars with the addition of sodium silicate coating were the most resistant to deterioration, moreover, the higher the GGBS/B ratio in the samples the more resilience it shows to the freezing-thawing cycles.
研究表明,在粘结剂质量(B)中加入磨碎的粒状高炉渣(GGBS)后,水玻璃涂层可显著抑制砂浆样品的劣化,涂层样品的抗冻融性能较未涂层样品有显著提高。该研究包括对4种不同GGBS/B比率(0%、30%、50%和70%)的砂浆样品进行冻融循环。对水玻璃的多种涂层(3层和6层)进行了冻融循环试验。在7、14、21、28和35个冻融循环中测量了所有砂浆样品的累积结垢。冻融性能试验表明,添加水玻璃涂层的砂浆最耐劣化,且GGBS/B比越高,对冻融循环的回弹性越大。
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引用次数: 0
Preclinical evaluation of analgesic activities of Barringtonia Racemosa 总状刺荆镇痛作用的临床前评价
Pub Date : 1900-01-01 DOI: 10.54660/.ijmrge.2023.4.1.381-385
A. Srujana, P. Lavanya, D. Padma Sri, K. Bhavani, Chouti Nikhitha, Derangula Shireesha
Background: Pain is the major devastating health problems. Barringtonia racemosa Roxb. (Lecythidaceae) is the one which is frequently used to treat pain by traditional healers in Ethiopian folk medicine. However, the plant has not been scientifically evaluated for its traditionally claimed use. The present study aimed at the investigation of analgesic activities of ethanol root extract of Barringtonia racemosa Roxb in Albino rats (Wistar) model. Methods: Successive maceration was used as a method of extraction using solvents ethanol. After extraction of the roots, the crude extract was evaluated for its analgesic activities using tail flick and hot plate method. The extract was evaluated at 100, 200 and 400 mg/kg doses. The positive control groups were treated with Aspirin 20 mg/ kg i.p, distilled water (10 mL/kg) treated rat were assigned as negative controls. Results: Barringtonia racemosa Roxb root extract at all test doses showed statistically significant antinociceptive activity in both model in a dose dependent manner (p < 0.01 and p < 0.001). The greater analgesic activity was observed by the maximum dose of the extract (400 mg/kg) in both tail flick and hot plate method method. Conclusion: In general, the data obtained from the present study elucidated that the extract possessed a significant analgesic activities and recommended for further studies.
背景:疼痛是主要的破坏性健康问题。总状白刺。(Lecythidaceae)是埃塞俄比亚民间医学中传统治疗师经常用来治疗疼痛的一种。然而,这种植物的传统用途尚未得到科学评估。本研究旨在研究总状白灵草乙醇根提取物对白化大鼠(Wistar)模型的镇痛作用。方法:采用连续浸渍法,乙醇溶剂提取。根提取后,采用甩尾法和热板法评价粗提物的镇痛活性。以100、200和400 mg/kg剂量对提取物进行评价。阳性对照组灌胃阿司匹林20 mg/ kg,阴性对照组灌胃蒸馏水10 mL/kg。结果:总形刺槐根提取物在两种模型中均具有显著的抗伤感受活性,且呈剂量依赖性(p < 0.01和p < 0.001)。甩尾法和热板法均以最大剂量(400 mg/kg)对大鼠有较强的镇痛作用。结论:总的来说,本研究数据表明该提取物具有明显的镇痛作用,值得进一步研究。
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引用次数: 0
Navicula sp Cell growth at different salinities 不同盐度下Navicula sp细胞的生长
Pub Date : 1900-01-01 DOI: 10.54660/.ijmrge.2023.4.1.401-405
W. ., Sinar Pagi Sektiana, B. Suprakto
Navicula sp is one of the microalgae which plays an important role in fish and shrimp hatchery activities. Navicula sp. which can detect the surrounding environment and is able to adapt to various salinities. The purpose of this study was to determine the optimal salinity level for the growth of Navicula sp. The research was carried out on March 9 - 22 2022. The research location was carried out at the Natural Feed Laboratory of the Brackish Water Aquaculture Fishery Center (BPBAP) Ujung Batee Province of Aceh. This study used an experimental method with a completely randomized design (CRD), with 4 treatments and 3 replications. The treatment in this study is the difference in salinity: A (10 g/l), B (20 g/l), C (30 g/l), D (40 g/l). The results showed that treatment B with a salinity of 20 g/l had a significant effect (P <.0.05) on the other treatments. The results of the Duncan Significant Difference Test showed that the maintenance medium with a salinity of 20 g/l had the highest cell density (5.63x106 cells/ml), followed by the maintenance medium with a salinity of 30 g/l with a cell density (5.20x106 cells/ml)
Navicula sp是在鱼虾孵化活动中起重要作用的微藻之一。能探测周围环境的Navicula sp.,能适应各种盐度。本研究的目的是确定Navicula sp.生长的最佳盐度水平。研究于2022年3月9日至22日进行。研究地点是亚齐乌戎巴提省咸淡水水产养殖渔业中心(BPBAP)的天然饲料实验室。本研究采用完全随机设计(CRD)的实验方法,4个处理,3个重复。本研究的处理是盐度的差异:A (10 g/l), B (20 g/l), C (30 g/l), D (40 g/l)。结果表明,盐度为20 g/l的处理B对其他处理有显著影响(P < 0.05)。Duncan显著差异试验结果显示,盐度为20 g/l的维持培养基的细胞密度最高,为5.63x106个细胞/ml,其次是盐度为30 g/l的维持培养基,细胞密度为5.20x106个细胞/ml。
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引用次数: 0
High performance concrete properties with varying curing agents 高性能混凝土性能与不同的养护剂
Pub Date : 1900-01-01 DOI: 10.54660/.ijmrge.2023.4.2.173-179
Mostafa M Ahmed, Kotaro Nose, T. Fujii, Toshiki Ayano
The Study shed the light on the effects of employing varied curing agents (No.1-No.6): bleeding water, and sprinkling water, aqueous basic silica compound, modified acrylic resin, emulsion of solid wax and nonionic surfactant, and water-based paraffin wax, on the properties of high-performance concrete (HPC) in comparison with the cured specimens according to the standard curing at 20 ± 3°C (JIS A 0203:2019). The specimens cured in accordance with standard curing exhibit a better compressive strength, and higher freeze-thaw resistance compared to most non-standard-cured samples. However, the special curing agents demonstrated higher resistance to moisture penetration as well as chloride ions infiltration.
本研究通过与20±3℃(JIS A 0203:2019)标准养护试件的对比,研究了不同养护剂(No.1-No.6):放水、洒水、水性碱性硅化合物、改性丙烯酸树脂、固体蜡与非离子表面活性剂乳液、水基石蜡对高性能混凝土(HPC)性能的影响。与大多数非标准养护试样相比,按照标准养护养护的试样具有更好的抗压强度和更高的抗冻融能力。然而,特殊的固化剂表现出更高的抗水分渗透和氯离子渗透的能力。
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引用次数: 0
Improvement of the physicochemical and microbiological properties of two traditional beers, Katata and Katubi, from the Haut-Katanga Province in the DRC 改进刚果民主共和国上加丹加省两种传统啤酒Katata和Katubi的理化和微生物特性
Pub Date : 1900-01-01 DOI: 10.54660/.ijmrge.2023.4.2.41-45
Célestin Muleka Kimpanga, Lydie Monga Safi, Eddy Mbuyu Ilunga, Elie Umba Kipanzula, Marsi Mbayo Kitambala, Roland Foma Kibwega, ET Jean-Pierre Mirhonyi Mugisho
This article presents some physicochemical and microbiological properties of two traditional drinks from the province of Haut-Katanga, Katata and Katubi, in the DRC. After centrifugation and filtration on Kieselghur, the analyzes showed that the two beers had an acid pH (respectively 3.65 and 3.85), the same alcohol content of 4.3%v, a transparent yellow colour, a pleasant appearance to view. Saccharomyces cerevisiae were highlighted there and no other bacteria.
本文介绍了两种传统饮料的一些物理化学和微生物特性从上加丹加省,卡塔塔和卡图比,在刚果民主共和国。在Kieselghur上进行离心和过滤后,分析表明这两种啤酒的pH值为酸性(分别为3.65和3.85),酒精含量相同,为4.3%v,呈透明的黄色,外观赏心悦目。在那里突出显示了酿酒酵母菌,没有其他细菌。
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引用次数: 0
期刊
International Journal of Multidisciplinary Research and Growth Evaluation
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