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Periorbital skin hypopigmentation associated with the use of topical glaucoma medications. 眼窝周围皮肤色素沉着与局部青光眼药物的使用有关。
Q3 Medicine Pub Date : 2025-03-24 eCollection Date: 2025-01-01 DOI: 10.5693/djo.02.2024.05.001
Sam Karimaghaei, Jeff Yee, Abdelrahman M Elhusseiny

Topical medications such as prostaglandin analogues, beta-blockers, alpha-2 agonists, and carbonic anhydrase inhibitors are routinely used for the management of ocular hypertension and glaucoma. Many are associated with adverse effects. We present the case of a 72-year-old woman who developed bilateral periocular hypopigmentation in the setting of long-term use of latanoprost, timolol, and brinzolamide/brimonidine. A well-known side effect of prostaglandin analogues is skin hyperpigmentation, but a few cases of a paradoxical hypopigmentation have been reported. Timolol and brinzolamide/brimonidine have not been associated with changes in skin pigmentation in the ophthalmic literature. Our case most likely represents a rare instance of paradoxical skin depigmentation associated with latanoprost use and adds to the limited literature on this clinical entity.

局部药物如前列腺素类似物、受体阻滞剂、α -2激动剂和碳酸酐酶抑制剂通常用于高眼压和青光眼的治疗。许多与不良反应有关。我们报告一位72岁的女性,长期使用拉坦前列素、替莫洛尔和布林唑胺/溴莫尼定后,出现双侧眼周色素沉着。前列腺素类似物的一个众所周知的副作用是皮肤色素沉着,但也有一些矛盾的色素沉着的病例被报道。在眼科文献中,噻莫洛尔和溴唑胺/溴胺与皮肤色素沉着的变化没有关联。我们的病例很可能代表了一个罕见的与拉坦前列素使用相关的反常皮肤色素沉着的实例,并增加了关于该临床实体的有限文献。
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引用次数: 0
Designing a workshop for a temporal artery biopsy simulation. 设计一个模拟颞动脉活检的工作坊。
Q3 Medicine Pub Date : 2025-03-19 eCollection Date: 2025-01-01 DOI: 10.5693/djo.01.2024.07.001
Shahzaib Rehan, Patrick Watts, Ian Williams, Paul Hennessy, Caomhnad O'Flaherty Farrell, Anjana Haridas

Purpose: To evaluate a wet-lab session designed to teach temporal artery biopsy (TAB) using simulation.

Methods: The Welsh Institute for Minimal Access Therapy Team (WIMAT) developed two simulation models using pig ureter for the temporal artery. The session consisted of consultant-led teaching on TAB surgical approaches, mapping the temporal artery with a Doppler device, and practical demonstrations with videos. Trainees performed two biopsies using the models under consultant supervision. Participants completed questionnaires to evaluate their pre- and post-session knowledge, understanding, and learning experiences. Three key areas of comparison were mapping the temporal artery, using an ultrasound doppler device, and performing a TAB.

Results: Seven specialist trainees (ST1-5) and 3 staff grade surgeons, supervised by 3 consultants, participated. Paired t test sampling showed statistically significant improvements in mapping the temporal artery (P = 0.0076), using an ultrasound Doppler device (P = 0.0002), and performing a TAB (P = 0.0002). Identified barriers included lack of knowledge, limited prior procedures, concern about damaging the facial nerve, and lack of senior support/supervision, which contributed to trainees' apprehension about performing TAB.

Conclusions: This innovative teaching event offers a blueprint for medical training programs to improve TAB training. Modern surgical education benefits from wet labs with expert supervision.

目的:评价采用模拟方法进行颞动脉活检(TAB)教学的湿实验室课程。方法:威尔士研究所最小通道治疗小组(WIMAT)开发了两种模拟模型,使用猪输尿管作为颞动脉。会议包括由顾问指导的TAB手术入路、用多普勒设备绘制颞动脉图以及视频演示。学员在顾问的监督下使用模型进行了两次活组织检查。参与者完成问卷来评估他们在会前和会后的知识、理解和学习经历。三个关键的比较领域是绘制颞动脉,使用超声多普勒设备,并执行TAB。结果:7名专科培训生(st - 1-5)和3名教职员级外科医生,由3名顾问指导。配对t检验抽样显示,在绘制颞动脉图(P = 0.0076)、使用超声多普勒设备(P = 0.0002)和执行TAB (P = 0.0002)方面有统计学上显著的改善。确定的障碍包括缺乏知识,有限的先前程序,担心损伤面神经,以及缺乏高级支持/监督,这些都导致了受训者对执行TAB的恐惧。结论:这一创新的教学活动为医学培训计划提供了一个蓝图,以改善TAB培训。现代外科教育得益于潮湿的实验室和专家的监督。
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引用次数: 0
Knowledge, attitude, and practice of parents of 3- to 5-year-olds regarding preschool vision and eye screening of kindergarten children in Al-Qassim Province, Saudi Arabia-a survey. 沙特阿拉伯Al-Qassim省3- 5岁儿童家长关于学龄前视力和幼儿园儿童眼睛筛查的知识、态度和实践调查
Q3 Medicine Pub Date : 2025-03-14 eCollection Date: 2025-01-01 DOI: 10.5693/djo.01.2024.06.003
Dora Hamad AlHarkan

Purpose: To assess the level and determinants of knowledge, attitude, and practice for eye and vision screening of preschool children among parents in Al-Qassim Province, Saudi Arabia.

Methods: Parents of kindergartners were surveyed in 2023. Questions relating to knowledge (10), attitude (5), and practice (5) of vision screening were asked. Answers were graded on a five-point Likert scale, where 1 indicates strong disagreement and 5 indicates strong agreement; results were analyzed with regard to family demographics and child refractive status.

Results: A total of 214 parents were surveyed, representing 214 households. Level of knowledge was good or very good in 66.2%, attitude was positive in 41%, and practice was acceptable in 72.2% of respondents. The median knowledge score was 4.0 (IQR, 3.5-4.0), median attitude score was 3.0 (IQR, 3.0-4.0), and median practice score was 4.0 (IQR, 3.0-4.0). Education and family income were associated with practice scores (P <0.001 [Kruskal-Wallis H test]). Refractive error status of the father was significantly associated with a positive attitude toward eye and vision screening of preschool children (P = 0.015 [Kruskal-Wallis]). Main sources of knowledge included ophthalmologists (49.5%), social media (16.4%), Google search (10.7%), and optometrists (10.7%); preferred sources of knowledge were ophthalmologists (60.3%) and optometrists (22.4%). Social media, computers, primary health care center staff, and opticians were less desired sources of information.

Conclusions: Parental knowledge on eye and vision screening for children in Al-Qassim Province has room to improve, and negative attitudes must be addressed. Practice for eye care in preschoolers was promising for adoption of universal preschool vision initiatives.

目的:评估沙特阿拉伯卡西姆省学龄前儿童家长对眼睛和视力筛查的知识、态度和做法的水平和决定因素。方法:于2023年对幼儿园家长进行问卷调查。对视力筛查的知识(10)、态度(5)和实践(5)进行问卷调查。答案按照李克特五分制打分,1分表示非常不同意,5分表示非常同意;结果分析了家庭人口统计和儿童屈光状态。结果:共有214名家长被调查,代表214个家庭。66.2%的受访者认为知识水平好或很好,41%的受访者认为态度积极,72.2%的受访者认为实践是可以接受的。知识得分中位数为4.0 (IQR, 3.5-4.0),态度得分中位数为3.0 (IQR, 3.0-4.0),实践得分中位数为4.0 (IQR, 3.0-4.0)。教育程度和家庭收入与实践成绩相关(P H检验)。父亲屈光不正状况与学龄前儿童眼睛视力筛查的积极态度显著相关(P = 0.015 [Kruskal-Wallis])。主要知识来源为眼科医生(49.5%)、社交媒体(16.4%)、谷歌搜索(10.7%)和验光师(10.7%);首选的知识来源是眼科医生(60.3%)和验光师(22.4%)。社交媒体、电脑、初级卫生保健中心工作人员和眼镜商是不太受欢迎的信息来源。结论:卡西姆省家长对儿童眼睛和视力筛查的了解仍有提高的空间,负面态度必须得到纠正。学龄前儿童的眼保健实践有望通过普遍的学前视力倡议。
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引用次数: 0
Unilateral idiopathic spontaneous filtering bleb repaired by donor scleral patch graft. 供体巩膜补片修复单侧特发性自发性滤过泡。
Q3 Medicine Pub Date : 2025-03-01 eCollection Date: 2025-01-01 DOI: 10.5693/djo.02.2024.06.001
Suyeon Yu, Daniel Polla, Elmira Baghdasaryan, Paras P Shah, Jules Winokur, David Ritterband, Isha M Cheela

We report the case of a 33-year-old woman with a history of hypothyroidism and ocular history of mild myopia who presented with a spontaneous filtering bleb. Extensive systemic rheumatologic evaluation was unrevealing. The bleb was observed for many months, until the patient's vision declined secondary to the development of hypotony maculopathy. The filtering bleb was closed using an allogenic scleral patch graft, resulting in normotensive intraocular pressure and improved best-corrected visual acuity. A unilateral, spontaneous filtering bleb is a rare occurrence and is typically associated with systemic or ocular conditions. Complications such as hypotony can lead to visual impairment, and intervention is required. Early diagnosis and repair with donor scleral patch graft can prevent complications and provide an excellent cosmetic outcome.

我们报告一例33岁女性甲状腺功能减退史和轻度近视史谁提出了一个自发滤过性水泡。广泛的全身风湿病学评估未显示。这个水泡观察了好几个月,直到患者的视力因黄斑低视病而下降。使用同种异体巩膜贴片关闭滤过泡,导致正常的眼压和改善最佳矫正视力。单侧自发滤过性水泡是罕见的,通常与全身或眼部疾病有关。低斜视等并发症可导致视力损害,需要进行干预。早期诊断和修复供体巩膜补片可以预防并发症和提供良好的美容效果。
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引用次数: 0
A 29-year-old woman with right lower lid mass. 29岁女性右下眼睑肿块。
Q3 Medicine Pub Date : 2025-02-23 eCollection Date: 2025-01-01 DOI: 10.5693/djo.03.2024.08.002
Syed Wajahat A Rizvi, Shagufta Qadri, Syed Ali R Rizvi, Saifullah Khalid, Mohammed Azfar Siddiqui, Syed Mustafa A Rizvi
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引用次数: 0
A previously unreported RPGR gene variant in a female patient with X-linked retinitis pigmentosa. 先前未报道的女性x连锁视网膜色素变性患者的RPGR基因变异。
Q3 Medicine Pub Date : 2025-02-22 eCollection Date: 2025-01-01 DOI: 10.5693/djo.02.2024.06.004
Mauricio Arango-Hurtado, Sara Turizo-Mejía, Luis M Jaramillo-Mayo, Karol Quintero-Lizcano

We present the case of a 40-year-old woman with a history of high myopia and nyctalopia. Her best-corrected visual acuity was 20/80 in the right eye and 20/100 in the left eye. Fundus examination revealed generalized vascular attenuation, optic nerve pallor, and bone spicule pigmentation. Fundus autofluorescence in both eyes showed a Robson-Holder ring in the macula and multiple hypoautofluorescent lesions in the peripheral retina. Macular optical coherence tomography scans revealed a generalized thinning of retinal layers, with atrophy of the outer retinal layers. 10-2 visual fields revealed a small island of central vision in both eyes, and full field electroretinogram showed absence of scotopic and photopic responses. Genetic studies documented a rare variant in the RPGR gene (c.1991C>G p.(Ser664*)). Findings compatible with retinitis pigmentosa in our patient suggests that this mutation is pathogenic. Further study is required to confirm this hypothesis.

我们提出的情况下,一个40岁的妇女与历史高度近视和夜盲症。最佳矫正视力为右眼20/80,左眼20/100。眼底检查显示血管广泛性衰减,视神经苍白,骨刺色素沉着。双眼眼底自身荧光显示黄斑有一个Robson-Holder环,视网膜周围有多个低自身荧光病变。黄斑光学相干断层扫描显示视网膜层普遍变薄,视网膜外层萎缩。10-2视野均可见中心视觉小岛,全视野视网膜电图无暗位和光位反应。遗传研究记录了一种罕见的RPGR基因变异(c.1991C >gp .(Ser664*))。本例患者视网膜色素变性的研究结果表明,该突变具有致病性。需要进一步的研究来证实这一假设。
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引用次数: 0
A growing pigmented iris lesion in a middle-aged white woman. 中年白人妇女虹膜色素病变。
Q3 Medicine Pub Date : 2025-02-11 eCollection Date: 2025-01-01 DOI: 10.5693/djo.02.2024.10.001
Marc Ohlhausen, Pukhraj Rishi

Melanocytomas are rare, benign tumors that occur most commonly on or adjacent to the optic disc, but they may be found in any part of the uveal tract. We report the case of a 68-year-old woman who presented with an asymptomatic melanocytic lesion on the iris of her right eye. Although it was initially observed and followed with serial imaging, the lesion was surgically removed via excisional biopsy after demonstrating interval growth. Subsequent pathological examination revealed the lesion to be a melanocytoma.

黑色素细胞瘤是一种罕见的良性肿瘤,最常见于视盘上或视盘附近,但也可在葡萄膜束的任何部位发现。我们报告的情况下,一个68岁的妇女谁提出了一个无症状的黑素细胞病变的虹膜她的右眼。虽然最初观察到病变并随后进行了一系列影像学检查,但在发现间期生长后,通过切除活检手术切除了病变。随后的病理检查显示病变为黑素细胞瘤。
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引用次数: 0
"Low-fat" intradermal spindle cell lipoma of the upper eyelid: a case report. 上眼睑“低脂”皮内梭形细胞脂肪瘤1例。
Q3 Medicine Pub Date : 2024-12-31 eCollection Date: 2024-01-01 DOI: 10.5693/djo.02.2024.06.005
Mary Kate Wilson, Elizabeth Goldberg, Aldo Fantin, Gulsun Erdag

Spindle cell lipomas are slow-growing, benign tumors composed of bland spindle cells, adipocytes, and collagen bundles. They are typically found on the posterior neck, shoulder, or upper back. Spindle cell lipomas represent only a small percentage of reported lipomatous tumor types. We report the case of a 90-year-old white man who presented with a solid mobile lesion on his right upper eyelid. Histopathological and immunohistochemical analysis of the lesion led to a diagnosis of a "low-fat," intradermal, spindle cell lipoma. This case underscores the importance of considering spindle cell lipoma in the differential diagnosis for atypical eyelid lesions.

梭形细胞脂肪瘤是生长缓慢的良性肿瘤,由平淡的梭形细胞、脂肪细胞和胶原束组成。它们通常出现在后颈部、肩部或上背部。梭形细胞脂肪瘤仅占报道的脂肪瘤类型的一小部分。我们报告的情况下,一个90岁的白人男子谁提出了一个坚实的移动病变在他的右上眼睑。病变的组织病理学和免疫组织化学分析导致诊断为“低脂,”皮内,梭形细胞脂肪瘤。本病例强调了在非典型眼睑病变鉴别诊断中考虑梭形细胞脂肪瘤的重要性。
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引用次数: 0
Primary anaplastic extramedullary plasmacytoma in the lacrimal sac. 泪囊内原发性间变性髓外浆细胞瘤。
Q3 Medicine Pub Date : 2024-09-30 eCollection Date: 2024-01-01 DOI: 10.5693/djo.02.2024.06.002
Abha Gupta, Khushdeep Abhaypal, Debajyoti Chatterjee, Manpreet Kaur, Manpreet Singh

We report the case of a 60-year-old man diagnosed with unilateral, solitary, extramedullary plasmacytoma located in the right lacrimal sac fossa, with no systemic involvement. This rare plasma cell dyscrasia is usually found in the respiratory tract. Clinical and radiological features of the mass and histopathological results are described. The patient was successfully treated with complete surgical excision. There were no clinical or radiological indications of disease recurrence at 10 months' follow-up.

我们报告的情况下,60岁的男子诊断为单侧,孤立,髓外浆细胞瘤位于右侧泪囊窝,没有全身累及。这种罕见的浆细胞病变通常见于呼吸道。描述了肿块的临床和放射学特征以及组织病理学结果。患者通过完全手术切除成功治疗。随访10个月无临床或影像学显示疾病复发。
{"title":"Primary anaplastic extramedullary plasmacytoma in the lacrimal sac.","authors":"Abha Gupta, Khushdeep Abhaypal, Debajyoti Chatterjee, Manpreet Kaur, Manpreet Singh","doi":"10.5693/djo.02.2024.06.002","DOIUrl":"10.5693/djo.02.2024.06.002","url":null,"abstract":"<p><p>We report the case of a 60-year-old man diagnosed with unilateral, solitary, extramedullary plasmacytoma located in the right lacrimal sac fossa, with no systemic involvement. This rare plasma cell dyscrasia is usually found in the respiratory tract. Clinical and radiological features of the mass and histopathological results are described. The patient was successfully treated with complete surgical excision. There were no clinical or radiological indications of disease recurrence at 10 months' follow-up.</p>","PeriodicalId":38112,"journal":{"name":"Digital journal of ophthalmology : DJO","volume":"30 3","pages":"60-63"},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11658778/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A 22-year-old woman with alcoholic pancreatitis and bilateral central scotomata. 22岁女性酒精性胰腺炎合并双侧中央黑斑。
Q3 Medicine Pub Date : 2024-08-18 eCollection Date: 2024-01-01 DOI: 10.5639/djo.03.2024.03.004
Tushar Dave, Keith D Yap, Aaron W Joe
{"title":"A 22-year-old woman with alcoholic pancreatitis and bilateral central scotomata.","authors":"Tushar Dave, Keith D Yap, Aaron W Joe","doi":"10.5639/djo.03.2024.03.004","DOIUrl":"10.5639/djo.03.2024.03.004","url":null,"abstract":"","PeriodicalId":38112,"journal":{"name":"Digital journal of ophthalmology : DJO","volume":"30 3","pages":"64-69"},"PeriodicalIF":0.0,"publicationDate":"2024-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11658779/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Digital journal of ophthalmology : DJO
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