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[Risk analysis Erosive Tooth Wear (ETW): checklist for a quick assessment of the risk factors for ETW in the dental practice]. [腐蚀性牙齿磨损(ETW)风险分析:快速评估牙科诊所中 ETW 风险因素的核对表]。
Q3 Medicine Pub Date : 2024-05-29 DOI: 10.61872/sdj-2024-02-11
Samira H Niemeyer, Thomas Jaeggi, Simon Ramseyer, Christian Tennert, Carola Imfeld, Adrian Lussi, Bedram Abou-Ayash

Erosive Tooth Wear (ETW) is the loss of tooth structure without bacterial involvement. As the resulting loss of tooth structure is irreversible, an early evaluation of the multifactorial etiology, accurate diagnosis and regular follow-up are essential. The ETW is dynamic and its progression should be continuously monitored. A risk analysis table was developed to systematically record risk factors for ETW (Fig. 2). This allows ETW management to be integrated more efficiently into clinical practice and the progression to be documented over the years. If ETW is assumed, the risk analysis should be performed and updated at least every two years. In the assessment, risk-promoting and risk-inhibiting factors are marked, added together and compared. If the negative factors pre-dominate, measures should be taken to minimize the risk for ETW. The main purpose of the risk analysis is therefore to evaluate the individual etiology, coun-teract negative factors, promote positive factors and prevent progression.

腐蚀性牙齿磨损(ETW)是指没有细菌参与的牙齿结构损失。由于所造成的牙齿结构损失是不可逆的,因此必须及早评估多因素病因、准确诊断和定期随访。ETW 是动态的,应持续监测其进展情况。为了系统地记录 ETW 的风险因素,我们制定了一个风险分析表(图 2)。这样就能更有效地将 ETW 管理纳入临床实践,并记录多年来的进展情况。如果假定存在 ETW,则应至少每两年进行一次风险分析和更新。在评估中,对风险促进因素和风险抑制因素进行标记、加总和比较。如果负面因素占主导地位,则应采取措施最大限度地降低 ETW 风险。因此,风险分析的主要目的是评估个人病因、抵消消极因素、促进积极因素和防止病情恶化。
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引用次数: 0
[Pyogenes Granulom - Ein Fallbericht]. [化脓性肉芽肿--病例报告]。
Q3 Medicine Pub Date : 2024-05-17 DOI: 10.61872/sdj-2024-03-05
Vranine Kadrija, C. Walter, Fabienne Andrina Bosshard
A pyogenic granuloma is an acquired, benign tissue formation of the skin and/or oral mucosa. Surgical excision is the most common treatment for these lesions. In this case report a case of a 60-year-old woman with a pyogenic granuloma in region 21 is presented. An excisional biopsy was performed with a CO2 laser under local anesthesia and the specimen was examined by a pathologist. No recurrency were observed in this case.
化脓性肉芽肿是皮肤和/或口腔粘膜后天形成的良性组织。手术切除是治疗这类病变最常见的方法。本病例报告了一名 60 岁女性的 21 号区域化脓性肉芽肿病例。在局部麻醉的情况下,使用二氧化碳激光进行了切除活检,并由病理学家对标本进行了检查。该病例未发现复发。
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引用次数: 0
Pyogenes Granulom - Ein Fallbericht [化脓性肉芽肿--病例报告]。
Q3 Medicine Pub Date : 2024-05-17 DOI: 10.61872/sdj-2024-03-05
Vranine Kadrija, Christiane Walter, Fabienne Andrina Bosshard

A pyogenic granuloma is an acquired, benign tissue formation of the skin and/or oral mucosa. Surgical excision is the most common treatment for these lesions. In this case report a case of a 60-year-old woman with a pyogenic granuloma in region 21 is presented. An excisional biopsy was performed with a CO2 laser under local anesthesia and the specimen was examined by a pathologist. No recurrency were observed in this case.

化脓性肉芽肿是皮肤和/或口腔粘膜后天形成的良性组织。手术切除是治疗这类病变最常见的方法。本病例报告了一名 60 岁女性的 21 号区域化脓性肉芽肿病例。在局部麻醉的情况下,使用二氧化碳激光进行了切除活检,并由病理学家对标本进行了检查。该病例未发现复发。
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引用次数: 0
A proof of concept on implant-supported bilateral cantilever bridges: The T-Bridge approach. 种植体支持的双侧悬臂桥概念验证:T 桥方法。
Q3 Medicine Pub Date : 2024-05-10 DOI: 10.61872/sdj-2024-03-04
Kelvin I Afrashtehfar, Bogna Stawarczyk, Danka Micovic Soldatovic, Patrick R Schmidlin

The concept of bilateral cantilevers on a single central implant (T-design) for three-unit implant-supported fixed dental prostheses (ISFDPs) has not been explored nor tested. This technical hypothesis aimed to explore the feasibility of such an approach as a cost-effective alternative to conventional treatments. Careful considerations regarding implant diameter, length, ideal position, occlusal scheme, and bone remodeling are essential to ensure adequate support, stability, and prevention of complications. In this proof of concept, we present a preliminary case with this novel design to replace missing posterior teeth in a patient with narrow bone conditions. In addition, a series of planned investigations and preliminary results, including preclinical studies, are presented to illustrate our concept and its potential clinical implications. Clinically, after two-year follow-up, healthy and stable peri-implant tissues around the ISFDP exemplarily demonstrated excellent stability, functionality, and comfort, which is supported by acceptable fracture resistance data in vitro, suggesting indeed the practical potential and suitability. Thus, we claim that such a treatment modality has the at least theoretical potential to revolutionize implant dentistry by providing innovative and cost-effective treatment options for patients with partial ISFDPs in very specific cases. Of course, further research and evaluations are necessary to validate the clinical implications of this innovative hypothesis. Implementing the 3-on-1 T-bridge approach in partial ISFDPs could offer a promising alternative to traditional methods. If proven successful, this technique may lead to significant advancements in clinical practice, providing a less invasive cost-effective treatment option.

在单个中心种植体上安装双侧悬臂(T型设计)用于三单位种植体支持的固定义齿修复体(ISFDP)的概念尚未被探索或测试。本技术假设旨在探索这种方法的可行性,以作为传统治疗方法的一种具有成本效益的替代方案。种植体的直径、长度、理想位置、咬合方案和骨重塑等方面的谨慎考虑对于确保足够的支持、稳定性和预防并发症至关重要。在这一概念验证中,我们介绍了一个采用这种新型设计的初步病例,用于替换一名骨质条件狭窄患者的后牙缺失。此外,我们还介绍了一系列计划中的调查和初步结果,包括临床前研究,以说明我们的概念及其潜在的临床意义。在临床上,经过两年的随访,ISFDP 周围健康稳定的种植体组织表现出了极佳的稳定性、功能性和舒适性,体外抗折性数据也证明了这一点,这表明它确实具有实用潜力和适用性。因此,我们认为,这种治疗方式至少在理论上具有革新种植牙的潜力,可以在非常特殊的病例中为部分 ISFDP 患者提供创新且具有成本效益的治疗方案。当然,要验证这一创新假设的临床意义,还需要进一步的研究和评估。在部分ISFDP中采用3对1 T桥的方法可以替代传统方法,前景广阔。如果这项技术被证明是成功的,那么它可能会在临床实践中取得重大进展,提供一种创伤较小、成本效益较高的治疗方案。
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引用次数: 0
A proof of concept on implant-supported bilateral cantilever bridges: The T-Bridge approach. 种植体支持的双侧悬臂桥概念验证:T 桥方法。
Q3 Medicine Pub Date : 2024-05-10 DOI: 10.61872/sdj-2024-03-04
K. I. Afrashtehfar, B. Stawarczyk, Danka Micovic Soldatovic, P. Schmidlin
The concept of bilateral cantilevers on a single central implant (T-design) for three-unit implant-supported fixed dental prostheses (ISFDPs) has not been explored nor tested. This technical hypothesis aimed to explore the feasibility of such an approach as a cost-effective alternative to conventional treatments. Careful considerations regarding implant diameter, length, ideal position, occlusal scheme, and bone remodeling are essential to ensure adequate support, stability, and prevention of complications. In this proof of concept, we present a preliminary case with this novel design to replace missing posterior teeth in a patient with narrow bone conditions. In addition, a series of planned investigations and preliminary results, including preclinical studies, are presented to illustrate our concept and its potential clinical implications. Clinically, after two-year follow-up, healthy and stable peri-implant tissues around the ISFDP exemplarily demonstrated excellent stability, functionality, and comfort, which is supported by acceptable fracture resistance data in vitro, suggesting indeed the practical potential and suitability. Thus, we claim that such a treatment modality has the at least theoretical potential to revolutionize implant dentistry by providing innovative and cost-effective treatment options for patients with partial ISFDPs in very specific cases. Of course, further research and evaluations are necessary to validate the clinical implications of this innovative hypothesis. Implementing the 3-on-1 T-bridge approach in partial ISFDPs could offer a promising alternative to traditional methods. If proven successful, this technique may lead to significant advancements in clinical practice, providing a less invasive cost-effective treatment option.
在单个中心种植体上安装双侧悬臂(T型设计)用于三单位种植体支持的固定义齿修复体(ISFDP)的概念尚未被探索或测试。本技术假设旨在探索这种方法的可行性,以作为传统治疗方法的一种具有成本效益的替代方案。种植体的直径、长度、理想位置、咬合方案和骨重塑等方面的谨慎考虑对于确保足够的支持、稳定性和预防并发症至关重要。在这一概念验证中,我们介绍了一个采用这种新型设计的初步病例,用于替换一名骨质条件狭窄患者的后牙缺失。此外,我们还介绍了一系列计划中的调查和初步结果,包括临床前研究,以说明我们的概念及其潜在的临床意义。在临床上,经过两年的随访,ISFDP 周围健康稳定的种植体组织表现出了极佳的稳定性、功能性和舒适性,体外抗折性数据也证明了这一点,这表明它确实具有实用潜力和适用性。因此,我们认为,这种治疗方式至少在理论上具有革新种植牙的潜力,可以在非常特殊的病例中为部分 ISFDP 患者提供创新且具有成本效益的治疗方案。当然,要验证这一创新假设的临床意义,还需要进一步的研究和评估。在部分ISFDP中采用3对1 T桥的方法可以替代传统方法,前景广阔。如果这项技术被证明是成功的,那么它可能会在临床实践中取得重大进展,提供一种创伤较小、成本效益较高的治疗方案。
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引用次数: 0
Oral health and nutritional status in care-dependent, community-dwelling older adults in Zurich, Switzerland. 瑞士苏黎世依赖护理、居住在社区的老年人的口腔健康和营养状况。
Q3 Medicine Pub Date : 2024-05-10 DOI: 10.61872/sdj-2024-02-09
Lea Angst, Patricia D Ferreira Lourenço, Murali Srinivasan

The aim of this study was to assess the oral health status (OHS), Oral health impact profile (OHIP-G-14), and the nutritional status (NS) in community-dwelling, dependent older adults. Information on OHS including DMF(T), plaque (PI) and gingival (GI) indices, community-periodontal-index-for-treatment-needs (CPITN), OHIP-G-14, maximum bite force (MBF), chewing efficiency [subjective (SA) and quantitative (VoH) assessments] were collected. NS was obtained by Mini-nutritional assessment (MNA) and body mass index (BMI). Cognitive status was evaluated by the mini-mental state examination (MMSE). 240 elders (mean-age = 81.5 ± 8.9y; men =85, women =155) were recruited. Average number of teeth, functional occlusal units and DMF(T), were 18.8 ± 8.9, 7.7 ± 3.5, and 22.3 ± 5.3 respectively. Mean PI, GI, CPITN and OHIP-G-14 were 1.8 ± 0.8, 1.2 ± 0.8, 1.9 ± 1.1, and 8.0 ± 12.0, respectively. MBF, VoH, SA were 219.6 ± 193.6, 0.3 ± 0.2, and 3.3 ± 1.4, respectively. MNA and BMI were 22.9 ± 4.7 and 25.5 ± 5.3, respectively. Number of teeth reduced significantly with age (P < 0.001), cognitive decline (P < 0.001). Oral hygiene significantly deteriorated with cognitive decline (P < 0.001). OHIP scores were negatively affected by increasing cognitive decline (P < 0.001). MNA deteriorated in women (P = 0.026), with increasing age (P = 0.015), and advancing cognitive decline (P < 0.001). BMI reduced with advancing age (P = 0.003) and in women (P = 0.016). Based on the findings of this study, it may be concluded that advancing age and cognitive decline, negatively impacted the oral health, oral function, oral health-related quality of life, and the nutritional state of care-dependent community-dwelling older adults.

本研究的目的是评估社区居住的依赖性老年人的口腔健康状况(OHS)、口腔健康影响档案(OHIP-G-14)和营养状况(NS)。收集的口腔健康状况信息包括 DMF(T)、牙菌斑(PI)和牙龈(GI)指数、社区牙周治疗需求指数(CPITN)、OHIP-G-14、最大咬合力(MBF)、咀嚼效率[主观(SA)和定量(VoH)评估]。通过小型营养评估(MNA)和体重指数(BMI)了解患者的营养状况。认知状况通过小型精神状态检查(MMSE)进行评估。共招募了 240 名老人(平均年龄为 81.5 ± 8.9 岁;男性 85 人,女性 155 人)。平均牙齿数、功能性咬合单位和 DMF(T) 分别为 18.8 ± 8.9、7.7 ± 3.5 和 22.3 ± 5.3。平均 PI、GI、CPITN 和 OHIP-G-14 分别为 1.8 ± 0.8、1.2 ± 0.8、1.9 ± 1.1 和 8.0 ± 12.0。MBF、VoH和SA分别为219.6 ± 193.6、0.3 ± 0.2和3.3 ± 1.4。MNA和BMI分别为22.9 ± 4.7和25.5 ± 5.3。牙齿数量随年龄(P < 0.001)和认知能力下降(P < 0.001)而明显减少。口腔卫生随认知能力下降而明显恶化(P < 0.001)。随着认知能力的下降,OHIP 分数也会受到负面影响(P < 0.001)。随着年龄的增长(P = 0.015)和认知能力的下降(P < 0.001),女性的 MNA 有所下降(P = 0.026)。随着年龄的增长(P = 0.003)和女性(P = 0.016),体重指数有所下降。根据这项研究的结果,我们可以得出结论:年龄的增长和认知能力的衰退会对依赖护理的社区老年人的口腔健康、口腔功能、与口腔健康相关的生活质量以及营养状况产生负面影响。
{"title":"Oral health and nutritional status in care-dependent, community-dwelling older adults in Zurich, Switzerland.","authors":"Lea Angst, Patricia D Ferreira Lourenço, Murali Srinivasan","doi":"10.61872/sdj-2024-02-09","DOIUrl":"https://doi.org/10.61872/sdj-2024-02-09","url":null,"abstract":"<p><p>The aim of this study was to assess the oral health status (OHS), Oral health impact profile (OHIP-G-14), and the nutritional status (NS) in community-dwelling, dependent older adults. Information on OHS including DMF(T), plaque (PI) and gingival (GI) indices, community-periodontal-index-for-treatment-needs (CPITN), OHIP-G-14, maximum bite force (MBF), chewing efficiency [subjective (SA) and quantitative (VoH) assessments] were collected. NS was obtained by Mini-nutritional assessment (MNA) and body mass index (BMI). Cognitive status was evaluated by the mini-mental state examination (MMSE). 240 elders (mean-age = 81.5 ± 8.9y; men =85, women =155) were recruited. Average number of teeth, functional occlusal units and DMF(T), were 18.8 ± 8.9, 7.7 ± 3.5, and 22.3 ± 5.3 respectively. Mean PI, GI, CPITN and OHIP-G-14 were 1.8 ± 0.8, 1.2 ± 0.8, 1.9 ± 1.1, and 8.0 ± 12.0, respectively. MBF, VoH, SA were 219.6 ± 193.6, 0.3 ± 0.2, and 3.3 ± 1.4, respectively. MNA and BMI were 22.9 ± 4.7 and 25.5 ± 5.3, respectively. Number of teeth reduced significantly with age (P < 0.001), cognitive decline (P < 0.001). Oral hygiene significantly deteriorated with cognitive decline (P < 0.001). OHIP scores were negatively affected by increasing cognitive decline (P < 0.001). MNA deteriorated in women (P = 0.026), with increasing age (P = 0.015), and advancing cognitive decline (P < 0.001). BMI reduced with advancing age (P = 0.003) and in women (P = 0.016). Based on the findings of this study, it may be concluded that advancing age and cognitive decline, negatively impacted the oral health, oral function, oral health-related quality of life, and the nutritional state of care-dependent community-dwelling older adults.</p>","PeriodicalId":38153,"journal":{"name":"Swiss dental journal","volume":"134 2","pages":"122-144"},"PeriodicalIF":0.0,"publicationDate":"2024-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140917141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early and late implant loss in a university-based periodontal setting: A retrospective analysis on 1821 patients and 2639 implants over a period of 18 years. 大学牙周环境中的早期和晚期种植体损失:对 18 年间 1821 名患者和 2639 个种植体的回顾性分析。
Q3 Medicine Pub Date : 2024-04-30 DOI: 10.61872/sdj-2024-02-08
Raffael Budmiger, Emir Peku, Jean-Claude Imber, Giovanni E Salvi, Alexandra Staehli, Andrea Roccuzzo

The aim of this study was to retrospectively analyze the implant failure rate, not due to peri-implantitis, in periodontally compromised patients rehabilitated with at least one dental implant placed in a specialist university setting over the last 18 years. Records of patients receiving dental implants at the Department of Periodontology, University of Bern, Switzerland, between 2005 and 2022 were analyzed. Data on 1821 patients with 2639 implants were retrieved. Fifty-nine patients experienced implant loss (rate at patient level: 3.2%) out of which 2.1% were early and 1.1% late implant losses, respectively. The majority of the 59 patients were males (68%) and 27.1% were smokers. Eight mm implants were lost with the highest rate (42.4%) followed by 10 mm implants (31.8%). The rate of lost maxillary implants was more than twice as high compared with that of mandibular implants (69.7 vs. 30.3%). Within the study limitations, the implant failure rate in this cohort of patients enrolled in regular supportive periodontal and peri-implant care, was low.

本研究旨在回顾性分析过去 18 年间在大学专科医院接受至少一次种植牙修复的牙周受损患者的种植失败率(非种植体周围炎所致)。我们对瑞士伯尔尼大学牙周病学系 2005 年至 2022 年期间接受牙科植入物治疗的患者记录进行了分析。共检索到 1,821 名患者、2639 个种植体的数据。59名患者经历过种植体脱落(患者比例:3.2%),其中2.1%为早期种植体脱落,1.1%为晚期种植体脱落。59 名患者中大部分为男性(68%),27.1%为吸烟者。8毫米种植体的丢失率最高(42.4%),其次是10毫米种植体(31.8%)。上颌种植体的脱落率是下颌种植体的两倍多(69.7% 对 30.3%)。由于研究的局限性,在这批定期接受牙周和种植体周围支持性护理的患者中,种植失败率较低。
{"title":"Early and late implant loss in a university-based periodontal setting: A retrospective analysis on 1821 patients and 2639 implants over a period of 18 years.","authors":"Raffael Budmiger, Emir Peku, Jean-Claude Imber, Giovanni E Salvi, Alexandra Staehli, Andrea Roccuzzo","doi":"10.61872/sdj-2024-02-08","DOIUrl":"https://doi.org/10.61872/sdj-2024-02-08","url":null,"abstract":"<p><p>The aim of this study was to retrospectively analyze the implant failure rate, not due to peri-implantitis, in periodontally compromised patients rehabilitated with at least one dental implant placed in a specialist university setting over the last 18 years. Records of patients receiving dental implants at the Department of Periodontology, University of Bern, Switzerland, between 2005 and 2022 were analyzed. Data on 1821 patients with 2639 implants were retrieved. Fifty-nine patients experienced implant loss (rate at patient level: 3.2%) out of which 2.1% were early and 1.1% late implant losses, respectively. The majority of the 59 patients were males (68%) and 27.1% were smokers. Eight mm implants were lost with the highest rate (42.4%) followed by 10 mm implants (31.8%). The rate of lost maxillary implants was more than twice as high compared with that of mandibular implants (69.7 vs. 30.3%). Within the study limitations, the implant failure rate in this cohort of patients enrolled in regular supportive periodontal and peri-implant care, was low.</p>","PeriodicalId":38153,"journal":{"name":"Swiss dental journal","volume":"134 2","pages":"105-121"},"PeriodicalIF":0.0,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140917139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Fibromatous Epulis: A Clinical Case Report]. [纤维瘤性外阴阴道炎:临床病例报告]。
Q3 Medicine Pub Date : 2024-04-05 DOI: 10.61872/sdj-2024-03-03
Sandra Fatori, Roksolana Burlaka, Heinz Theo Lübbers, Reinhild Zenklusen, Andreas Filippi

A 35-year-old patient presented with a painless, broad-based exophytic lesion in the buccal interdental region between teeth 13 and 14. Despite oral hygiene efforts the lesion persisted for around one year. Radiology excluded bone involvement, and histopathology after excision confirmed a fibromatous epulis, which is characterized by collagen-rich connective tissue. There was no recurrence within one-year follow-up. Surgical removal proved to be efficient.

一名 35 岁的患者在第 13 和第 14 颗牙齿之间的颊面牙间区出现了一个无痛、广基底的外生性病变。尽管努力保持口腔卫生,但病变仍持续了一年左右。放射学检查排除了骨受累的可能性,切除后的组织病理学检查证实这是一种纤维瘤性外生病变,其特征是富含胶原蛋白的结缔组织。在一年的随访中没有复发。手术切除证明是有效的。
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引用次数: 0
[Autologous platelet concentrates in regenerative dentistry - A narrative literature review. Part I: Theoretical and legal aspects of the PR(G)F application]. [再生牙科中的自体血小板浓缩物--叙事性文献综述。第一部分:PR(G)F 应用的理论和法律方面]。
Q3 Medicine Pub Date : 2024-04-05 DOI: 10.61872/sdj-2024-05-02
Oliver P Ernst, Liza L Ramenzoni, Patrick R Schmidlin

The use of autologous platelet concentrates (APC) such as platelet-rich fibrin (PRF) and/or plasma rich in growth factors (PRGF®) is considered an established treatment modality in re-generative dentistry. The possibility of delivering growth factors over aclinically relevant time of several days seems particularly interesting in the context of wound healing.The growing body of evidence in the field of APC requires a continuous and actual knowledge of the literature for being able to make evidence-based treatment recommendations with a realistic assessment of possible advantages of this technology.PR(G)F can be applied in solid or liquid form, pure or in combination with other biomaterials. Both appear to be reasonable, depending on the clinical indication and/or desired treatment outcomes. Because of the many different factors that can affect the PR(G)F products final characteristics, a basic understanding of these parameters is desirable for choosing the most suitable product and/or optimizing its clinical application. This review aims to provide an over-view of relevant theoretical, practical, legal and biologic aspects of APCs.

使用自体血小板浓缩物 (APC),如富含血小板的纤维蛋白 (PRF) 和/或富含生长因子的血浆 (PRGF®) 被认为是再生牙科中一种成熟的治疗方式。在伤口愈合的背景下,在数天的临床相关时间内提供生长因子的可能性似乎特别令人感兴趣。APC 领域的证据越来越多,需要对文献进行持续和实际的了解,以便能够提出基于证据的治疗建议,并对该技术可能具有的优势进行现实的评估。PR(G)F可以固态或液态形式应用,也可以纯生物材料或与其他生物材料结合应用。根据临床适应症和/或预期治疗效果,这两种形式似乎都很合理。由于有许多不同的因素会影响 PR(G)F 产品的最终特性,因此需要对这些参数有基本的了解,以便选择最合适的产品和/或优化其临床应用。本综述旨在概述 APCs 的相关理论、实践、法律和生物学方面。
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引用次数: 0
Effect of lozenge surface texture, taste and acidity on salivary flow rate: A crossover preclinical trial in healthy subjects. 含片表面质地、味道和酸度对唾液流速的影响:健康受试者的交叉临床前试验。
Q3 Medicine Pub Date : 2024-02-27 DOI: 10.61872/sdj-2024-02-05
Claudio A B Bianchetti, Fabio Saccardin, Andreas Filippi

Dry mouth is a multifaceted condition which is caused by reduced salivary secretion. This study aimed to evaluate and compare the effects of different lozenge surface textures, tastes and acidity levels on stimulated salivary secretion for increased oral moistening in participants without hyposalivation. This randomized, double-blind, clinical crossover trial with before and after comparison involved 33 healthy volunteers. Five lozenges, including a baseline control (C), apple (A), sour (S), sour apple (SA) and granular pectin (P) were tested on five different days with all the subjects. Salivary flow, pH value, and subjective feeling (visual analog scale) were measured before and after consuming the lozenge each day. Throughout all trial days the unstimulated whole salivary flow (UWSF) averaged 0.65 ± 0.26 ml/min. Lozenges S, SA, and P showed higher stimulated whole salivary flow (SWSF) than C (P < 0.001) by more than 0.5 ml/min. Lozenge P, with a rough surface, demonstrated the highest difference between UWSF and SWSF, 2.41 ± 0.69 ml/min. The stimulated saliva with the lozenges containing acidifiers (S, SA and P) was more than 1.4 pH units lower compared to lozenges C and A (P < 0.001). Subjects reported the strongest subjective feeling of increased saliva with lozenges SA and P. Overall lozenges SA and P provided the best objective results in enhancing salivary flow rate and subjective feeling of increased salivary flow.

口干是一种由唾液分泌减少引起的多方面疾病。本研究旨在评估和比较不同锭剂表面质地、口味和酸度对刺激唾液分泌以增加口腔湿润的效果,受试者不存在唾液分泌过少的情况。这项随机、双盲、前后对比的临床交叉试验涉及 33 名健康志愿者。所有受试者在五个不同的日子里接受了五种锭剂的测试,包括基线对照(C)、苹果(A)、酸(S)、酸苹果(SA)和颗粒果胶(P)。每天在食用菱形糖前后测量唾液流量、pH 值和主观感觉(视觉模拟量表)。在所有试验日中,未刺激全唾液流量(UWSF)平均为 0.65 ± 0.26 毫升/分钟。S、SA 和 P 润喉糖的刺激全唾液流量(SWSF)比 C 润喉糖高(P < 0.001)0.5 毫升/分钟以上。表面粗糙的 P 润喉糖的全唾液流量(UWSF)和全唾液流量(SWSF)之间的差异最大,为 2.41 ± 0.69 毫升/分钟。与 C 和 A 相比,含有酸味剂的含片(S、SA 和 P)刺激唾液的 pH 值低 1.4 个单位以上(P < 0.001)。总体而言,SA 和 P 润喉糖在提高唾液流速和增加唾液流量的主观感觉方面提供了最佳的客观效果。
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引用次数: 0
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Swiss dental journal
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