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P07 David vs. Goliath: CTCA versus invasive angiography in previous bypass patients presenting with NSTEACS P07大卫与歌利亚:CTCA与侵入性血管造影在既往旁路治疗的NSTEACS患者中的应用
Pub Date : 2020-09-01 DOI: 10.1136/heartjnl-2020-bsci.20
S. Hill, S. Thiru, A. Farag
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引用次数: 0
P06 Establishing a new cut off of calcium score P06建立钙评分新分界线
Pub Date : 2020-09-01 DOI: 10.1136/HEARTJNL-2020-BSCI.19
C. Józsa, E. Cheasty
Introduction CT coronary angiography (CTCA) is the preferred test in patients with low to intermediate likelihood of coronary artery disease. This retrospective study was conducted to determine a new cut for calcium score without adversely affecting the diagnostic accuracy of CTCA. Methods CTCA was performed on a third generation dual-source CT scanner (Siemens Force 512 slice). Agatston method was used for the quantification of the coronary artery calcium. The degree of luminal narrowing was classified using the CAD-RAD scoring system. The coronary plaques were classified into calcified, non-calcified and mixed subtypes. We reviewed the results of any subsequent non-invasive (stress echocardiography, cardiac magnetic resonance perfusion imaging) and invasive (coronary angiography) tests to assess the correlation with CTCA. Results 296 patients were included in the analysis. 22% (64/296) did not go on to further investigations. 78% (232/296) underwent non-invasive or invasive tests. The correlation of CTCA with further investigations did not depend on total calcium score. 76% of CTCAs correlated with further investigations, 5% did not correlate and 19% had inconclusive results. (Multiple artefacts preventing complete CTCA interpretation). Conclusion The correlation or non-correlation of the CTCA results with further investigations was not affected by the total calcium score. Therefore we deem it is reasonable to proceed with a CTCA even when the calcium score exceeds 1000.
CT冠状动脉造影(CTCA)是低到中等可能性冠状动脉疾病患者的首选检查。本回顾性研究旨在确定一种不影响CTCA诊断准确性的钙评分新方法。方法在第三代双源CT扫描仪(Siemens Force 512层)上进行CTCA。冠状动脉钙定量采用Agatston法。采用CAD-RAD评分系统对管腔狭窄程度进行分类。冠状动脉斑块分为钙化型、非钙化型和混合型。我们回顾了所有随后的非侵入性(应激超声心动图、心脏磁共振灌注成像)和侵入性(冠状动脉造影)试验的结果,以评估与CTCA的相关性。结果296例患者纳入分析。22%(64/296)未进行进一步调查。78%(232/296)接受了非侵入性或侵入性检查。CTCA与进一步检查的相关性不依赖于总钙评分。76%的ctca与进一步调查相关,5%不相关,19%结果不确定。(多重伪影妨碍完整的CTCA解释)。结论CTCA结果与进一步检查的相关或不相关不受总钙评分的影响。因此,我们认为即使钙评分超过1000,也可以进行CTCA检查。
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引用次数: 0
P05 Acute cardiac CT pathway for troponin negative chest pain P05肌钙蛋白阴性胸痛的急性心脏CT通路
Pub Date : 2020-03-01 DOI: 10.1136/HEARTJNL-2020-BSCI.18
Z. Khan, S. Elfawal, A. Deshpande
Introduction The acute cardiac CT pathway was set up at University hospitals of Leicester in 2017 to provide early outpatient Cardiac CT slots for patients presenting to hospital with Troponin negative chest pain to exclude coronary artery disease (CAD). A slot was created in each Cardiac CT list. Prior to this, patients would remain inpatients for up to 48 hours waiting for a scan or would have an outpatient scan after 10–20 weeks in 50% of cases. Methods Data was collected retrospectively from the radiology information system for the time period between September 2017 and August 2019 and analysed with regards to the time from request received to scan performed, degree of stenosis and management. Results Data for 116 patients was collected of which 9 were excluded due to patient cancellation or equipment failure. Of the remaining 107, the average time from request received to scan performed was 9.9 days. CT coronary angiogram (CTCA) was reported as normal in 50 cases and mild stenosis in 30 cases. There were 3 patent stents and grafts. Three patients had zero calcium but no CTCA performed. Two patients had high calcium score and no CTCA. One of these went onto have CABG. Stenosis was reported ranging from moderate to severe in 19 patients; 6 of these had stent insertions. Conclusion The acute Cardiac CT pathway demonstrated a substantial reduction in average waiting times to 9.9 days and allows earlier management of obstructive CAD in those patients presenting with Troponin negative chest pain.
2017年,莱斯特大学附属医院建立了急性心脏CT通路,为因肌钙蛋白阴性胸痛就诊的患者提供早期门诊心脏CT槽位,以排除冠心病(CAD)。在每个心脏CT列表中创建一个槽。在此之前,在50%的病例中,患者将在住院长达48小时等待扫描或在10-20周后进行门诊扫描。方法回顾性收集2017年9月至2019年8月期间放射学信息系统的数据,分析从收到请求到进行扫描的时间、狭窄程度和处理。结果共收集116例患者资料,其中9例因患者取消或设备故障而被排除。在剩下的107例中,从收到请求到执行扫描的平均时间为9.9天。CT冠状动脉造影(CTCA)正常50例,轻度狭窄30例。支架和移植物3例。3例患者无钙,但未行CTCA。2例患者钙评分高,无CTCA。其中一个做了冠脉搭桥。19例患者出现中度至重度狭窄;其中6例植入了支架。结论:急性心脏CT路径显示平均等待时间大幅减少至9.9天,并允许对那些出现肌钙蛋白阴性胸痛的阻塞性CAD患者进行早期治疗。
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引用次数: 0
P04 FFRCT: Benefits and limitations. a tertiary centre experience at glenfield hospital/university of hospitals leicester P04 FFRCT:优点和局限性。在格伦菲尔德医院/莱斯特大学医院三级中心的经验
Pub Date : 2020-03-01 DOI: 10.1136/HEARTJNL-2020-BSCI.17
S. Elfawal, Z. Khan, A. Bajaj, I. Das, P. Rao, R. Machin, A. Deshpande
Introduction FFRCT is a novel software for analysis of CT coronary angiographic images and aims to identify flow limiting disease non-invasively. FFRCT was introduced in our regular practice at ‘UHL’ in April 2018. This audit sought to assess the utility of FFRCT in evaluating the functional significance of all potentially flow limiting stenosis as seen on conventional CT. Methods We reviewed all cases which were sent for FFRCT analyses from April 2018 to December 2019. Patients with FFRCT values of >0.80 and Results A total of 222 cases were sent for FFRCT analysis to Heartflow. FFRCT was 0.80 in 100 patients in at least one coronary vessel. Invasive angiogram was performed in 59 of these patients, of which 50 had CTFFR 0.80. Of these, 35 patients had stents or were referred to surgery. Five of the patients that had revascularisation, had a CT FFR of >0.8. Conclusion We found that FFRCT has a valuable role in assessing the significance of moderate to severe stenosis on CTCA. Interpretation of FFRCT results needs to be made with caution and in conjunction with the CT angiographic images, as the quality of CT images may impact the accuracy of CT FFR values.
FFRCT是一种用于分析CT冠状动脉造影图像的新型软件,旨在无创地识别血流受限疾病。FFRCT于2018年4月在“UHL”的常规实践中引入。本次审核旨在评估FFRCT在评估常规CT上所见的所有潜在限流狭窄的功能意义方面的效用。方法回顾2018年4月至2019年12月所有送去FFRCT分析的病例。FFRCT值>0.80的患者共222例被送至Heartflow进行FFRCT分析。100例患者中至少有一条冠状血管的FFRCT为0.80。59例患者行有创血管造影,其中50例患者CTFFR为0.80。其中,35名患者接受了支架或手术治疗。5例血运重建患者的CT FFR >0.8。结论FFRCT在评估中重度狭窄对CTCA的意义上具有重要的价值。对FFRCT结果的解释需要谨慎,并结合CT血管造影图像,因为CT图像的质量可能会影响CT FFR值的准确性。
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引用次数: 0
P01 Heartflow: experience of a high-volume district general hospital P01心脏流动:大容量地区综合医院的经验
Pub Date : 2020-03-01 DOI: 10.1136/HEARTJNL-2020-BSCI.14
S. Qayyum, Abubakar Habib, Svyatoslav Kechyn, D. Auger, N. Damani, A. Griguer, N. Hadjiloizou, P. Jain, N. Keenan, Masood Khan, Anish Prabhakar, Kevin Rosenfeld, J. Sehmi
Introduction HeartFlow is a non-invasive technique for estimating fractional flow reserve (FFRCT) from computer tomography coronary angiography (CTCA). HeartFlow has been made available via an NHS England funded program since September 2018 and is now fully embedded within our stable chest pain pathway. The aim of this work was to evaluate the impact of HeartFlow, which replaced previous practice of stress testing for patients with moderate coronary lesions, and invasive angiography for those with severe stenoses on CTCA. Methods We reviewed 360 consecutive patients who underwent CTCA and FFRCT between September 2018 and June 2019. CT coronary angiograms and HeartFlow models were read by a cardiologist and radiologist. Clinical records of all patients were reviewed. Results All patients referred for FFRCT had coronary stenoses greater than 50%. 72% had FFRCT≥0.8 and were discharged. 26% had FFRCT Conclusion Our study demonstrates the impact of HeartFlow in a high-volume CTCA service. Two thirds of patients referred for HeartFlow, who would previously have undergone downstream testing, had negative results and the pathway stopped at that point. Of the patients referred for invasive assessment, significant disease was found in two thirds, and in one third significant stenoses were not identified.
HeartFlow是一种通过计算机断层冠状动脉造影(CTCA)估计血流储备分数(FFRCT)的无创技术。自2018年9月以来,HeartFlow已通过英国NHS资助的项目提供,现在已完全嵌入我们稳定的胸痛通路中。这项工作的目的是评估HeartFlow的影响,它取代了以前对中度冠状动脉病变患者的压力测试,以及对严重狭窄患者的侵入性血管造影。方法我们回顾了2018年9月至2019年6月期间连续360例接受CTCA和FFRCT的患者。CT冠状动脉造影和心脏血流模型由心脏病专家和放射科医生阅读。回顾所有患者的临床记录。结果所有经FFRCT检查的患者冠脉狭窄程度均大于50%。72% FFRCT≥0.8,出院。结论:我们的研究证明了HeartFlow在大容量CTCA服务中的影响。三分之二接受心脏流动治疗的患者,之前会进行下游检测,结果为阴性,这一途径就停止了。在接受有创评估的患者中,三分之二的患者发现了明显的疾病,三分之一的患者没有发现明显的狭窄。
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引用次数: 1
P14 Downstream investigation following CT coronary angiography: an audit of practice in a UK centre CT冠状动脉造影后的下游调查:对英国中心实践的审计
Pub Date : 2020-01-20 DOI: 10.1136/HEARTJNL-2020-BSCI.27
A. Amlani, G. Benedetti, S. Mak, R. Preston
Introduction In the UK, national guidance on the assessment of cardiac sounding chest pain (NICE CG95 2016), advises that CT coronary angiography (CTCA) is the first line imaging modality. If this reveals coronary artery disease of uncertain functional significance or is non-diagnostic, non-invasive functional testing is advised as second line. Invasive coronary angiography is only advocated as third-line when functional imaging is inconclusive or if intervention is planned and should not be performed merely to ‘check’ CTCA. We present an audit to assess the adherence to this national guidance in our centre. Methods Retrospective analysis of 281 consecutive CTCA performed between July 2017 to June 2018 and October 2018 to January 2019. Data collected include demographics, CAD-RADS score, and the presence/absence of any subsequent functional imaging, invasive angiography, PCI, or CABG up until the data collection time-point (September 2019). Results 276 scans were suitable for analysis and, out of these, 231 (84%) were discharged without further investigation. A total of 24 patients underwent subsequent functional imaging and 25 underwent invasive coronary angiography; in 16 of these patients (64%) no revascularisation was performed. Conclusion Overall adherence to the guidelines at our institution is good with the majority of patients (84%) discharged without further investigation. Importantly, in 64% of patients undergoing invasive angiography no intervention was performed, suggesting that some of these may be unnecessary.
在英国,关于心源性胸痛评估的国家指南(NICE CG95 2016)建议,CT冠状动脉造影(CTCA)是一线成像方式。如果这显示出功能意义不确定的冠状动脉疾病,或者是非诊断性的,建议非侵入性功能检查作为二线。侵入性冠状动脉造影仅在功能成像不确定或计划干预时才被提倡作为第三线,而不应仅仅“检查”CTCA。我们提出了一项审核,以评估本中心对本国家指导方针的遵守情况。方法回顾性分析2017年7月至2018年6月、2018年10月至2019年1月连续行CTCA的281例患者。收集的数据包括人口统计数据、CAD-RADS评分,以及在数据收集时间点(2019年9月)之前是否存在任何后续功能成像、侵入性血管造影、PCI或CABG。结果276例扫描适合分析,其中231例(84%)出院,未作进一步调查。共有24例患者接受了随后的功能成像,25例接受了有创冠状动脉造影;其中16例(64%)未行血运重建术。结论我院对指南的总体遵守情况良好,大多数患者(84%)出院时未作进一步检查。重要的是,在接受有创血管造影的患者中,64%的患者没有进行干预,这表明其中一些干预可能是不必要的。
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引用次数: 0
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Scientific poster abstracts
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