Pub Date : 2024-07-18DOI: 10.1016/j.rec.2024.05.015
Francisco González-Vílchez, Luis Almenar-Bonet, Cristina Mitroi, María G Crespo-Leiro, Amador López-Granados, María Valero, Juan F Delgado-Jiménez, Sonia Mirabet-Pérez, José M Sobrino-Márquez, Elena García-Romero
Introduction and objectives: Our aim was to describe the characteristics and outcomes of heart transplants in Spain.
Methods: We analyzed trends in recipient and donor characteristics, recipient-donor interaction, surgical procedures, immunosuppression, and outcomes of patients included in the Spanish heart transplant registry from 2014 to 2023. Changes in survival were analyzed using the Kaplan-Meier method.
Results: In 2023, 325 cardiac transplants were performed (4.5% more than in the previous year), with a total of 2987 procedures from 2014 to 2023. There was a trend toward performing more transplants in women (29.2%), with etiologies other than cardiomyopathy (32.6%), and with better pretransplant status (less hepatic [12.5%], renal [glomerular filtration rate, 81.5mL/min/1.73 m2], and respiratory [8.7%] involvement). In 2023, the number of urgent transplants increased (44% of the total), especially those performed after circulatory support with extracorporeal membrane oxygenation (36% of total assistance), and transplants performed with donation after circulatory death (17.9%). Survival improved in the triennium from 2020 to 2022 compared with 2014 to 2016 (83.0% at 1 year from 2020-2022 vs 79.0% from 2014-2016).
Conclusions: The number of transplants performed in Spain showed an upward trend, with recipients with better clinical status and an increasing use of donation after circulatory death. Survival improved in the last triennium.
{"title":"Spanish heart transplant registry. 35th official report of the Heart Failure Association of the Spanish Society of Cardiology.","authors":"Francisco González-Vílchez, Luis Almenar-Bonet, Cristina Mitroi, María G Crespo-Leiro, Amador López-Granados, María Valero, Juan F Delgado-Jiménez, Sonia Mirabet-Pérez, José M Sobrino-Márquez, Elena García-Romero","doi":"10.1016/j.rec.2024.05.015","DOIUrl":"10.1016/j.rec.2024.05.015","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>Our aim was to describe the characteristics and outcomes of heart transplants in Spain.</p><p><strong>Methods: </strong>We analyzed trends in recipient and donor characteristics, recipient-donor interaction, surgical procedures, immunosuppression, and outcomes of patients included in the Spanish heart transplant registry from 2014 to 2023. Changes in survival were analyzed using the Kaplan-Meier method.</p><p><strong>Results: </strong>In 2023, 325 cardiac transplants were performed (4.5% more than in the previous year), with a total of 2987 procedures from 2014 to 2023. There was a trend toward performing more transplants in women (29.2%), with etiologies other than cardiomyopathy (32.6%), and with better pretransplant status (less hepatic [12.5%], renal [glomerular filtration rate, 81.5mL/min/1.73 m<sup>2</sup>], and respiratory [8.7%] involvement). In 2023, the number of urgent transplants increased (44% of the total), especially those performed after circulatory support with extracorporeal membrane oxygenation (36% of total assistance), and transplants performed with donation after circulatory death (17.9%). Survival improved in the triennium from 2020 to 2022 compared with 2014 to 2016 (83.0% at 1 year from 2020-2022 vs 79.0% from 2014-2016).</p><p><strong>Conclusions: </strong>The number of transplants performed in Spain showed an upward trend, with recipients with better clinical status and an increasing use of donation after circulatory death. Survival improved in the last triennium.</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":null,"pages":null},"PeriodicalIF":7.2,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141735253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-14DOI: 10.1016/j.rec.2024.06.006
Peijian Wei, Yihang Li, Fengwen Zhang, Zhongying Xu, Liang Xu, Junyi Wan, Shiguo Li, Wenbin Ouyang, Shouzheng Wang, Gejun Zhang, Gary Tse, Jeffrey Shi Kai Chan, Fang Fang, Xiangbin Pan
Introduction and objectives: This study aimed to retrospectively analyze the anatomical characteristics and classification of multiple coronary artery fistulas (MCAFs), and to compare the outcomes of transcatheter closure between MCAFs and single fistulas.
Methods: All patients who underwent attempts at transcatheter closure of coronary artery fistulas (CAFs) at Fuwai Hospital from 2010 to 2023 were retrospectively reviewed. Patients were categorized into single fistula and MCAFs groups, and anatomical characteristics and transcatheter closure outcomes were compared between the 2 groups.
Results: This retrospective study included 146 patients who underwent attempted transcatheter closure of CAFs, with a 14.38% failure rate. Among the 146 patients with CAFs, 32.19% were identified as having MCAFs, with types I, II, and III constituting 40.43%, 42.55%, and 17.02%, respectively. Unlike single fistulas, which predominantly originated from the right coronary artery and terminated in the left ventricle, MCAFs mainly had simultaneous origins from the right coronary artery and left anterior descending artery (29.79%), and predominantly drained into the pulmonary artery (70.21%), with a notable prevalence of plexus-like morphology (38.3% vs 2.02%, P<.001). The success rate of transcatheter closure was significantly lower for multiple fistulas compared with single fistula (64.29% vs 84.34%, P=.011). Multivariate regression analysis indicated that the risk of closure failure for MCAFs was 2.64 times that of single fistulas.
Conclusions: MCAFs are common among CAFs and can be classified into 3 types based on the number and location of their origins and terminations. The risk of failure of transcatheter closure is significantly higher in MCAFs than in single fistulas.
导言和目的：本研究旨在回顾性分析多发性冠状动脉瘘（MCAFs）的解剖学特征和分类，并比较多发性冠状动脉瘘和单发性冠状动脉瘘的经导管封堵效果：方法：回顾性研究2010年至2023年期间在阜外医院尝试经导管闭合冠状动脉瘘（CAFs）的所有患者。将患者分为单个瘘管组和 MCAFs 组，比较两组患者的解剖学特征和经导管闭合结果：这项回顾性研究纳入了146例尝试经导管闭合CAFs的患者，失败率为14.38%。在 146 名 CAFs 患者中，32.19% 被确认为患有 MCAFs，其中 I 型、II 型和 III 型分别占 40.43%、42.55% 和 17.02%。与主要起源于右冠状动脉并终止于左心室的单发瘘不同，MCAFs主要同时起源于右冠状动脉和左前降支动脉（29.79%），并主要排入肺动脉（70.21%），其神经丛样形态的发生率明显高于单发瘘（38.3% vs 2.02%，P < .001）。与单个瘘管相比，多个瘘管的经导管闭合成功率明显较低（64.29% vs 84.34%，P = .011）。多变量回归分析表明，MCAFs的闭合失败风险是单个瘘管的2.64倍：结论：MCAFs 是 CAFs 中常见的一种，可根据其起源和终止的数量和位置分为 3 种类型。MCAF经导管闭合失败的风险明显高于单个瘘管。
{"title":"Transcatheter closure of multiple coronary artery fistulas: a coronary computed tomography angiography-based anatomic classification.","authors":"Peijian Wei, Yihang Li, Fengwen Zhang, Zhongying Xu, Liang Xu, Junyi Wan, Shiguo Li, Wenbin Ouyang, Shouzheng Wang, Gejun Zhang, Gary Tse, Jeffrey Shi Kai Chan, Fang Fang, Xiangbin Pan","doi":"10.1016/j.rec.2024.06.006","DOIUrl":"10.1016/j.rec.2024.06.006","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>This study aimed to retrospectively analyze the anatomical characteristics and classification of multiple coronary artery fistulas (MCAFs), and to compare the outcomes of transcatheter closure between MCAFs and single fistulas.</p><p><strong>Methods: </strong>All patients who underwent attempts at transcatheter closure of coronary artery fistulas (CAFs) at Fuwai Hospital from 2010 to 2023 were retrospectively reviewed. Patients were categorized into single fistula and MCAFs groups, and anatomical characteristics and transcatheter closure outcomes were compared between the 2 groups.</p><p><strong>Results: </strong>This retrospective study included 146 patients who underwent attempted transcatheter closure of CAFs, with a 14.38% failure rate. Among the 146 patients with CAFs, 32.19% were identified as having MCAFs, with types I, II, and III constituting 40.43%, 42.55%, and 17.02%, respectively. Unlike single fistulas, which predominantly originated from the right coronary artery and terminated in the left ventricle, MCAFs mainly had simultaneous origins from the right coronary artery and left anterior descending artery (29.79%), and predominantly drained into the pulmonary artery (70.21%), with a notable prevalence of plexus-like morphology (38.3% vs 2.02%, P<.001). The success rate of transcatheter closure was significantly lower for multiple fistulas compared with single fistula (64.29% vs 84.34%, P=.011). Multivariate regression analysis indicated that the risk of closure failure for MCAFs was 2.64 times that of single fistulas.</p><p><strong>Conclusions: </strong>MCAFs are common among CAFs and can be classified into 3 types based on the number and location of their origins and terminations. The risk of failure of transcatheter closure is significantly higher in MCAFs than in single fistulas.</p>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":null,"pages":null},"PeriodicalIF":7.2,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141621150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-08DOI: 10.1016/j.rec.2024.06.005
Roger Benet-Pozo, Montserrat Fitó, Jaume Marrugat, Cosme García-García, Isaac Subirana, Roberto Elosua
{"title":"Does the amount and intensity of physical activity matter for low-density lipoprotein oxidation?","authors":"Roger Benet-Pozo, Montserrat Fitó, Jaume Marrugat, Cosme García-García, Isaac Subirana, Roberto Elosua","doi":"10.1016/j.rec.2024.06.005","DOIUrl":"10.1016/j.rec.2024.06.005","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":null,"pages":null},"PeriodicalIF":7.2,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-08DOI: 10.1016/j.rec.2024.05.012
Javier Lorenzo González, Marcos Farráis Villalba, Cristina López Ferraz, Sergio Huertas Nieto, Mar Martín Velasco, Julio Hernández Afonso
{"title":"Impact of an integrated cardiology-intensive care medicine model on mortality in STEMI.","authors":"Javier Lorenzo González, Marcos Farráis Villalba, Cristina López Ferraz, Sergio Huertas Nieto, Mar Martín Velasco, Julio Hernández Afonso","doi":"10.1016/j.rec.2024.05.012","DOIUrl":"10.1016/j.rec.2024.05.012","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":null,"pages":null},"PeriodicalIF":7.2,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-03DOI: 10.1016/j.rec.2024.05.010
{"title":"Correction in the article by de Juan Bagudá et al. “Repetitive ambulatory levosimendan as a bridge to heart transplantation”, Rev Esp Cardiol. 2024;77:290-301","authors":"","doi":"10.1016/j.rec.2024.05.010","DOIUrl":"10.1016/j.rec.2024.05.010","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":null,"pages":null},"PeriodicalIF":7.2,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1885585724001890/pdfft?md5=5081e72648c9c679e7f4f045ceee4719&pid=1-s2.0-S1885585724001890-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141535594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.1016/j.rec.2024.01.007
María Sabater Molina , Juan Ramón Gimeno Blanes
{"title":"In recognition of the Spanish origin of CRISPR/Cas9. Implications for the treatment of familial heart disease","authors":"María Sabater Molina , Juan Ramón Gimeno Blanes","doi":"10.1016/j.rec.2024.01.007","DOIUrl":"10.1016/j.rec.2024.01.007","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":null,"pages":null},"PeriodicalIF":7.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139933392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.1016/j.rec.2024.01.004
Raban V. Jeger, Gregor Fahrni
{"title":"Rest in PEACE?","authors":"Raban V. Jeger, Gregor Fahrni","doi":"10.1016/j.rec.2024.01.004","DOIUrl":"10.1016/j.rec.2024.01.004","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":null,"pages":null},"PeriodicalIF":7.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139693123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.1016/j.rec.2023.12.013
Rocío Párraga , Carlos Real , Rodrigo Fernández-Jiménez
{"title":"Cardiovascular magnetic resonance in the working diagnosis of MINOCA: the sooner, the better?","authors":"Rocío Párraga , Carlos Real , Rodrigo Fernández-Jiménez","doi":"10.1016/j.rec.2023.12.013","DOIUrl":"10.1016/j.rec.2023.12.013","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":null,"pages":null},"PeriodicalIF":7.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139687661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.1016/j.rec.2023.12.007
Ryoung-Eun Ko , Jihye Lee , Sungeun Kim , Joong Hyun Ahn , Soo Jin Na , Jeong Hoon Yang
Introduction and objectives
Delirium, recognized as a crucial prognostic factor in the cardiac intensive care unit (CICU), has evolved in response to the changing demographics among critically ill cardiac patients. This study aimed to create a predictive model for delirium for patients in the CICU.
Methods
This study included consecutive patients admitted to the CICU of the Samsung Medical Center. To assess the candidate variables for the model: we applied the following machine learning methods: random forest, extreme gradient boosting, partial least squares, and Plmnet-elastic.net. After selecting relevant variables, we performed a logistic regression analysis to derive the model formula. Internal validation was conducted using 100-repeated hold-out validation.
Results
We analyzed 2774 patients, 677 (24.4%) of whom developed delirium in the CICU. Machine learning-based models showed good predictive performance. Clinically significant and frequently important predictors were selected to construct a delirium prediction scoring model for CICU patients. The model included albumin level, international normalized ratio, blood urea nitrogen, white blood cell count, C-reactive protein level, age, heart rate, and mechanical ventilation. The model had an area under the receiver operating characteristics curve (AUROC) of 0.861 (95%CI, 0.843-0.879). Similar results were obtained in internal validation with 100-repeated cross-validation (AUROC, 0.854; 95%CI, 0.826-0.883).
Conclusions
Using variables frequently ranked as highly important in four machine learning methods, we created a novel delirium prediction model. This model could serve as a useful and simple tool for risk stratification for the occurrence of delirium at the patient's bedside in the CICU.
{"title":"Machine learning methods for developing a predictive model of the incidence of delirium in cardiac intensive care units","authors":"Ryoung-Eun Ko , Jihye Lee , Sungeun Kim , Joong Hyun Ahn , Soo Jin Na , Jeong Hoon Yang","doi":"10.1016/j.rec.2023.12.007","DOIUrl":"10.1016/j.rec.2023.12.007","url":null,"abstract":"<div><h3>Introduction and objectives</h3><p>Delirium, recognized as a crucial prognostic factor in the cardiac intensive care unit (CICU), has evolved in response to the changing demographics among critically ill cardiac patients. This study aimed to create a predictive model for delirium for patients in the CICU.</p></div><div><h3>Methods</h3><p>This study included consecutive patients admitted to the CICU of the Samsung Medical Center. To assess the candidate variables for the model: we applied the following machine learning methods: random forest, extreme gradient boosting, partial least squares, and Plmnet-elastic.net. After selecting relevant variables, we performed a logistic regression analysis to derive the model formula. Internal validation was conducted using 100-repeated hold-out validation.</p></div><div><h3>Results</h3><p>We analyzed 2774 patients, 677 (24.4%) of whom developed delirium in the CICU. Machine learning-based models showed good predictive performance. Clinically significant and frequently important predictors were selected to construct a delirium prediction scoring model for CICU patients. The model included albumin level, international normalized ratio, blood urea nitrogen, white blood cell count, C-reactive protein level, age, heart rate, and mechanical ventilation. The model had an area under the receiver operating characteristics curve (AUROC) of 0.861 (95%CI, 0.843-0.879). Similar results were obtained in internal validation with 100-repeated cross-validation (AUROC, 0.854; 95%CI, 0.826-0.883).</p></div><div><h3>Conclusions</h3><p>Using variables frequently ranked as highly important in four machine learning methods, we created a novel delirium prediction model. This model could serve as a useful and simple tool for risk stratification for the occurrence of delirium at the patient's bedside in the CICU.</p></div>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":null,"pages":null},"PeriodicalIF":7.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139492373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.1016/j.rec.2024.04.010
Miguel Ángel García Fernández , Luis Rodríguez Padial
{"title":"Leandro Plaza Celemín","authors":"Miguel Ángel García Fernández , Luis Rodríguez Padial","doi":"10.1016/j.rec.2024.04.010","DOIUrl":"10.1016/j.rec.2024.04.010","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":null,"pages":null},"PeriodicalIF":7.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1885585724001531/pdfft?md5=57396734e5b92710e40dfa798d04ed4e&pid=1-s2.0-S1885585724001531-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140944283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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