Revista española de cardiología (English ed.)最新文献

{"title":"Systematic triplet expansion testing in patients with genetically negative Brugada syndrome","authors":"Alexis Hermida , Guillaume Jedraszak , Flavie Ader , Philippe Maury , Philippe Charron , Estelle Gandjbakhch","doi":"10.1016/j.rec.2025.04.005","DOIUrl":"10.1016/j.rec.2025.04.005","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"79 2","pages":"Pages 178-180"},"PeriodicalIF":4.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Classification, prevalence and cardiovascular risk of different types of hypercholesterolemia","authors":"Fernando Civeira ,&nbsp;Estíbaliz Jarauta ,&nbsp;Victoria Marco-Benedí ,&nbsp;Ana M. Bea ,&nbsp;Rocío Mateo-Gallego ,&nbsp;Itziar Lamiquiz-Moneo ,&nbsp;Irene Gracia-Rubio ,&nbsp;Daniel Bello-Álvarez ,&nbsp;Martín Laclaustra ,&nbsp;María Teresa Tejedor ,&nbsp;Salvador Olmos ,&nbsp;Ana Cenarro","doi":"10.1016/j.rec.2025.07.004","DOIUrl":"10.1016/j.rec.2025.07.004","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>The frequency, clinical characteristics and risk of atherosclerotic cardiovascular disease (ASCVD) of the different types of hypercholesterolemia are not well established. The primary and secondary objectives of this study were to determine the cause of hypercholesterolemia and whether the cause confers a different ASCVD prognosis.</div></div><div><h3>Methods</h3><div>The analysis included 3474 probands with primary hypercholesterolemia, of whom 3283 (94.8%) were followed up for 9.33<!--> <!-->± 5.8 years for ASCVD. Genetic analysis of familial hypercholesterolemia (FH) genes, polygenic risk score for hypercholesterolemia, and lipid concentrations, including lipoprotein(a), were used to classify hypercholesterolemia.</div></div><div><h3>Results</h3><div>The diagnoses were heterozygous FH, n<!--> <!-->=<!--> <!-->400 (11.5%); hyperlipoproteinemia(a), n<!--> <!-->=<!--> <!-->181 (5.2%); polygenic hypercholesterolemia, n<!--> <!-->=<!--> <!-->434 (12.5%); hyperlipoproteinemia(a) plus polygenic hypercholesterolemia, n<!--> <!-->=<!--> <!-->128 (3.7%); multifactorial, n<!--> <!-->=<!--> <!-->1562 (45.0%); and idiopathic, n<!--> <!-->=<!--> <!-->769 (22.1%). At baseline, low-density lipoprotein cholesterol levels were higher in heterozygous FH, and the prevalence of ASCVD was higher in hyperlipoproteinemia(a). Other clinical and biochemical characteristics did not differ among hypercholesterolemia subgroups. The survival rate was lower in participants with hyperlipoproteinemia(a) than in the other hypercholesterolemia groups (<em>P</em> <!-->=<!--> <!-->.001). Variables independently associated with ASCVD events during follow-up were age, male sex, the presence of ASCVD, diabetes or hypertension at baseline, current smoking, lipoprotein(a) concentration, and high-density lipoprotein cholesterol concentration, the latter being inversely associated with ASCVD events. Total mortality was independent of the type of hypercholesterolemia.</div></div><div><h3>Conclusions</h3><div>Genetic hypercholesterolemia has a worse prognosis for ASCVD than nongenetic hypercholesterolemia. Among individuals with genetic hypercholesterolemia, those with elevated lipoprotein(a) have the worst prognosis. Conventional lipid-lowering treatment for low-density lipoprotein cholesterol appears to be less effective in hypercholesterolemia due to hyperlipoproteinemia(a) than in other forms of hypercholesterolemia.</div></div>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"79 2","pages":"Pages 131-141"},"PeriodicalIF":4.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144812558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reduced stent strategy versus conventional percutaneous coronary revascularization in patients presenting with STEMI: design of the COPERNICAN trial","authors":"Jorge Sanz-Sánchez ,&nbsp;Sandra Santos Martínez ,&nbsp;Eva Rumiz González ,&nbsp;Juan Francisco Oteo Domínguez ,&nbsp;David Tejada Ponce ,&nbsp;Antonio Gómez Menchero ,&nbsp;Guillermo Sánchez Elvira ,&nbsp;Georgina Fuertes Ferre ,&nbsp;Fernando Rivero Crespo ,&nbsp;Antonela Lukic Otanovic ,&nbsp;José Díaz Fernández ,&nbsp;Eladio Galindo Fernández ,&nbsp;Cristóbal Urbano Carrillo ,&nbsp;Neus Salvatella Giralt ,&nbsp;Mauricio Torres Sánchez ,&nbsp;Arturo García Touchard ,&nbsp;Borja Ibáñez Cabeza ,&nbsp;Giulio Stefanini ,&nbsp;Fernando Alfonso Manterola ,&nbsp;Héctor García García ,&nbsp;Ignacio J. Amat-Santos","doi":"10.1016/j.rec.2025.05.005","DOIUrl":"10.1016/j.rec.2025.05.005","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Primary percutaneous coronary intervention (PCI) with drug-eluting stent implantation (DES) is the standard of treatment in patients presenting with ST-segment elevation myocardial infarction (STEMI). However, target lesion failure can occur due to stent underexpansion, malapposition, hypersensitivity, fracture, and neoatherosclerosis. Drug-coated balloons (DCB) represent a potential alternative supported by the concept of “leaving nothing behind.” The aim is to compare a reduced stent strategy based on DCB- with DES-PCI in patients presenting with STEMI.</div></div><div><h3>Methods</h3><div>Prospective, pragmatic, multicenter, noninferiority, randomized clinical trial.</div></div><div><h3>Results</h3><div>A total of 1 272 patients presenting with STEMI will be randomized to any paclitaxel-DCB vs any sirolimus-DES (both with CE approval) for all culprit and nonculprit lesions during PCI. The primary endpoint will be target-lesion failure: cardiac death, target-vessel myocardial infarction, or ischemia-driven target lesion revascularization at 12-month follow-up. An independent clinical events committee masked to treatment allocation will adjudicate all suspected events. Clinical follow-up will be performed after 1 month (30 days<!--> <!-->±<!--> <!-->5 days) and 1 year (365 days<!--> <!-->±<!--> <!-->30 days). An extended follow-up at 3, 5, and 10 years is planned.</div></div><div><h3>Conclusions</h3><div>The COPERNICAN trial will be the first randomized study comparing clinical outcomes of DCB vs DES in STEMI patients.</div><div>ClinicalTrials.gov: <span><span>NCT06353594</span><svg><path></path></svg></span>.</div></div>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"79 2","pages":"Pages 100-105"},"PeriodicalIF":4.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fewer stents for STEMI. Are DCBs ready for prime time?","authors":"Bruno Scheller","doi":"10.1016/j.rec.2025.08.007","DOIUrl":"10.1016/j.rec.2025.08.007","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"79 2","pages":"Pages 106-107"},"PeriodicalIF":4.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypertrophic cardiomyopathy with sequential intracavitary obstruction resolved by mavacamten","authors":"Margarida G. Figueiredo,&nbsp;José Miguel Viegas,&nbsp;Sílvia Aguiar Rosa","doi":"10.1016/j.rec.2025.08.001","DOIUrl":"10.1016/j.rec.2025.08.001","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"79 2","pages":"Pages 187-188"},"PeriodicalIF":4.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TTN cardiomyopathy: expanding clinical relevance beyond the A-band","authors":"María Valverde-Gómez ,&nbsp;Luis De La Higuera-Romero ,&nbsp;Marlene Pérez-Barbeito ,&nbsp;Soledad García-Hernández ,&nbsp;Ivonne Cárdenas-Reyes ,&nbsp;Juan Pablo Ochoa","doi":"10.1016/j.rec.2025.07.001","DOIUrl":"10.1016/j.rec.2025.07.001","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"79 2","pages":"Pages 184-186"},"PeriodicalIF":4.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Drug-coated balloon-based versus drug-eluting stent-only treatment for single de novo diffuse coronary lesions","authors":"Eun-Seok Shin ,&nbsp;Sunwon Kim ,&nbsp;Dong Oh Kang ,&nbsp;Bitna Kim ,&nbsp;Ae-Young Her","doi":"10.1016/j.rec.2025.07.003","DOIUrl":"10.1016/j.rec.2025.07.003","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>There are limited data on drug-coated balloon (DCB) treatment for de novo diffuse coronary artery disease (CAD). This study aimed to evaluate the clinical impact of DCB-based percutaneous coronary intervention (PCI) in patients with de novo diffuse long CAD.</div></div><div><h3>Methods</h3><div>We retrospectively included 623 patients with single de novo diffuse CAD (≥ 30<!--> <!-->mm). These patients underwent PCI exclusively for the target lesion and were successfully treated with DCB-based PCI. They were compared with 623 propensity-matched patients who underwent conventional PCI with second-generation drug-eluting stents (DES) for diffuse CAD (DES-only group). The primary endpoint was major adverse cardiovascular events (MACE), defined as a composite of cardiac death, myocardial infarction, stent or target lesion thrombosis, target vessel revascularization, and major bleeding at 2 years.</div></div><div><h3>Results</h3><div>In the DCB-based group, 73.7% of patients were treated with DCB alone. The MACE rate was significantly lower in the DCB-based group than in the DES-only group (4.6% vs 14.6%; HR, 0.29; 95%CI, 0.18-0.47; <em>P</em> <!-->&lt;<!--> <!-->.001). Rates of target vessel revascularization (3.1% vs 9.7%; <em>P</em> <!-->&lt;<!--> <!-->.001) and major bleeding events (0.8% vs 2.7%; <em>P</em> <!-->=<!--> <!-->.008) were also lower with DCB-based PCI than with DES-only PCI. In a multivariable model, DCB-based PCI was independently associated with a lower risk of 2-year MACE, target vessel revascularization, and major bleeding.</div></div><div><h3>Conclusions</h3><div>In patients with de novo diffuse CAD, DCB-based PCI was associated with a significant reduction in MACE compared with DES-only PCI.</div></div>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"79 2","pages":"Pages 108-116"},"PeriodicalIF":4.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intermediate cardiac care units: rationale, resources, and admission criteria. Position statement of the SEC-ACICAC","authors":"Ana Viana-Tejedor ,&nbsp;Pedro Martínez Losas ,&nbsp;Rut Andrea-Riba ,&nbsp;Miguel Corbí-Pascual ,&nbsp;Sandra Rosillo ,&nbsp;Joaquín J. Alonso ,&nbsp;Alessandro Sionís ,&nbsp;Pablo Pastor ,&nbsp;Pablo Jorge-Pérez ,&nbsp;Cosme García-García","doi":"10.1016/j.rec.2025.10.004","DOIUrl":"10.1016/j.rec.2025.10.004","url":null,"abstract":"<div><div>Intermediate cardiac care units (IMCU) provide a level of care between hospital wards and cardiac acute care units. They are designed for patients who require close monitoring or noncritical support, such as those with acute coronary syndromes, acute heart failure (HF), arrhythmias, monitoring after structural interventional cardiology or electrophysiology procedures, or postoperative care following cardiac surgery. IMCU help optimize resources and relieve pressure on cardiac acute care units, thereby improving specialized care. Two levels of IMCU are defined: level 1, which offers noninvasive monitoring and basic life support, and level 2, which incorporates invasive arterial pressure monitoring, noninvasive mechanical ventilation, and equipment for complex procedures. Their structure should be functional, with single-patient rooms, effective communication with other services, and dedicated areas for health care personnel. Care is led by cardiologists with specific training, supported by highly specialized nursing staff, and requires continuous medical coverage (24<!--> <!-->hours a day, 7 days a week) based on well-defined clinical protocols. This model aims to provide efficient, safe, and excellence-driven care. The Spanish Society of Cardiology (SEC) promotes its development through this position statement of the SEC Ischemic Heart Disease and Acute Cardiovascular Care Association (SEC-ACICAC), intended to guide the implementation of IMCU in Spain.</div></div>","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"79 2","pages":"Pages 165-172"},"PeriodicalIF":4.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145356417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction in article by Molina-Lerma et al. “Spanish pacemaker registry. 21st official report of Heart Rhythm Association of the Spanish Society of Cardiology (2023)”, Rev Esp Cardiol. 2024;77:947–956","authors":"","doi":"10.1016/j.rec.2025.11.003","DOIUrl":"10.1016/j.rec.2025.11.003","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"79 2","pages":"Page 191"},"PeriodicalIF":4.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transfemoral recanalization of atretic aortic arch using radiofrequency wire","authors":"Stefano Svab ,&nbsp;Alain Fraisse ,&nbsp;Konstantinos Dimopoulos ,&nbsp;Isma Rafiq ,&nbsp;Harith Alam ,&nbsp;Alexander Kempny","doi":"10.1016/j.rec.2025.04.001","DOIUrl":"10.1016/j.rec.2025.04.001","url":null,"abstract":"","PeriodicalId":38430,"journal":{"name":"Revista española de cardiología (English ed.)","volume":"79 2","pages":"Pages 173-175"},"PeriodicalIF":4.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144019119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}