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Revista española de cardiología (English ed.)最新文献

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Rest in PEACE? 安息?
IF 7.2 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-07-01 DOI: 10.1016/j.rec.2024.01.004
Raban V. Jeger, Gregor Fahrni
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引用次数: 0
Impact of prior use of antiplatelets on COVID-19 susceptibility, progression, and severity: a population-based study 先前使用抗血小板对 COVID-19 易感性、进展和严重程度的影响:一项基于人群的研究
IF 7.2 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-07-01 DOI: 10.1016/j.rec.2023.12.004
Ángela Prieto-Campo , Maruxa Zapata-Cachafeiro , Manuel Portela-Romero , María Piñeiro-Lamas , Adolfo Figueiras , Ángel Salgado-Barreira

Introduction and objectives

Hypercoagulability and thromboembolism are processes that arise from severe acute respiratory syndrome coronavirus 2 infection and are responsible for a high degree of coronavirus disease 2019 (COVID-19)-related morbidity and mortality. This study sought to assess the effect of antiplatelet drugs on COVID-19 severity (risk of hospitalization and mortality), susceptibility to severe acute respiratory syndrome coronavirus 2 infection, and progression to severe COVID-19.

Methods

We conducted a population-based case-control study in a northwestern region of Spain in 2020. The study involved 3060 participants with a positive polymerase chain reaction test who were hospitalized, 26 757 participants with a positive polymerase chain reaction test who were not hospitalized, and 56 785 healthy controls.

Results

Triflusal seemed to be associated with a significant increase in risk of hospitalization (aOR, 1.97; 95%CI, 1.27-3.04) and susceptibility to infection (OR, 1.45; 95%CI, 1.07-1.96). It also appeared to lead to a nonsignificant increase in the risk of mortality (OR, 2.23; 95%CI, 0.89-5.55) and/or progression to more severe disease stages (OR, 1.42; 95%CI, 0.8-2.51). Aspirin seemed to be associated with a statistically significant decrease in susceptibility to severe acute respiratory syndrome coronavirus 2 infection (OR, 0.92; 95%CI, 0.86-0.98).

Conclusions

Triflusal use appears to increase the risk of susceptibility to COVID-19 infection and an even higher risk of hospitalization, whereas the other antiplatelets could be associated with a reduction in the risk of the various outcomes or have no effect on risk. These findings could support reconsideration of triflusal prescription in COVID-19 pandemic situations.

引言和目的高凝状态和血栓栓塞是严重急性呼吸综合征冠状病毒2感染引起的过程,也是冠状病毒2019病(COVID-19)相关发病率和死亡率居高不下的原因。本研究旨在评估抗血小板药物对 COVID-19 严重程度(住院和死亡风险)、严重急性呼吸综合征冠状病毒 2 感染易感性以及进展为严重 COVID-19 的影响。方法我们于 2020 年在西班牙西北部地区开展了一项基于人群的病例对照研究。结果三氟草胺似乎与住院风险(aOR,1.97;95%CI,1.27-3.04)和感染易感性(OR,1.45;95%CI,1.07-1.96)的显著增加有关。阿司匹林似乎也会导致死亡风险的非显著性增加(OR,2.23;95%CI,0.89-5.55)和/或疾病发展到更严重阶段(OR,1.42;95%CI,0.8-2.51)。阿司匹林似乎与严重急性呼吸系统综合征冠状病毒 2 感染的易感性显著降低有关(OR,0.92;95%CI,0.86-0.98)。结论使用三氟片似乎会增加 COVID-19 感染的易感性风险,甚至会增加住院风险,而其他抗血小板药物可能会降低各种结果的风险或对风险没有影响。这些发现可支持在COVID-19大流行的情况下重新考虑三氟沙星的处方。
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引用次数: 0
Leandro Plaza Celemín Leandro Plaza Celemín.
IF 7.2 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-07-01 DOI: 10.1016/j.rec.2024.04.010
Miguel Ángel García Fernández , Luis Rodríguez Padial
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引用次数: 0
Heritable pulmonary arterial hypertension in rats with spontaneous systemic hypertension 自发性系统性高血压大鼠的遗传性肺动脉高压。
IF 7.2 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-07-01 DOI: 10.1016/j.rec.2024.01.010
Francisco Javier Roldán Gómez , Alberto Aranda Fraustro , Laura Gómez Soto , Tomás Pulido Zamudio , Alicia Sánchez Mendoza , José A. Barbosa Carreño
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引用次数: 0
ChatGPT-4 versus human assessment in cardiology peer review 心脏病学同行评审中的 ChatGPT-4 与人工评估。
IF 7.2 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-07-01 DOI: 10.1016/j.rec.2024.02.004
Agustín Fernández-Cisnal , Pablo Avanzas , David Filgueiras-Rama , Pablo Garcia-Pavia , Laura Sanchis , Juan Sanchis
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引用次数: 0
Effect of the Mediterranean diet in cardiovascular prevention 地中海饮食对预防心血管疾病的影响。
IF 7.2 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-07-01 DOI: 10.1016/j.rec.2024.01.006
Miguel Á. Martínez-González , Aitor Hernández Hernández

The Mediterranean diet is the best evidence-based model for cardiovascular prevention. In addition to 2 major randomized secondary prevention trials (Lyon Heart and CORDIOPREV) and 1 primary prevention trial (PREDIMED) that have demonstrated these benefits, there is an unprecedented body of high-quality prospective epidemiological evidence supporting these beneficial effects. The key elements of this traditional pattern are the abundant use of extra-virgin olive oil and high consumption of foods of natural plant-based origin (fruits, vegetables, nuts, and legumes) and fish, along with a reduction in processed meats, red meats, and ultraprocessed products. Moderate consumption of wine, preferably red wine, with meals is an essential element of this traditional pattern. Although removing wine consumption from the Mediterranean diet has been associated with a reduction in its preventive efficacy, doubts have recently arisen about the possible adverse effect of even low or moderate intake of any alcoholic beverages. A new large Spanish trial, UNATI, which will begin in June 2024, will randomize 10 000 drinkers aged 50 to 75 years to abstention or moderate consumption. UNATI aims to answer these doubts with the best possible evidence.

地中海饮食是预防心血管疾病的最佳循证模式。除了 2 项主要的随机二级预防试验(里昂心脏试验和 CORDIOPREV 试验)和 1 项一级预防试验(PREDIMED 试验)证明了这些益处外,还有大量前所未有的高质量前瞻性流行病学证据支持这些有益的效果。这种传统模式的关键要素是大量使用特级初榨橄榄油,多吃天然植物性食物(水果、蔬菜、坚果和豆类)和鱼类,同时减少加工肉类、红肉和超加工产品。用餐时适量饮用葡萄酒,最好是红葡萄酒,是这种传统模式的基本要素。虽然从地中海饮食中剔除葡萄酒的摄入量会降低其预防效果,但最近又有人怀疑即使少量或适量摄入任何酒精饮料也可能产生不良影响。一项新的西班牙大型试验 UNATI 将于 2024 年 6 月开始,它将随机抽取 10 000 名 50 至 75 岁的饮酒者,让他们选择戒酒或适量饮酒。UNATI 的目标是用最好的证据来回答这些疑问。
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引用次数: 0
Adjusted morbidity groups and geriatric assessment in older patients with acute coronary syndrome 急性冠状动脉综合征老年患者的调整发病率组别和老年评估。
IF 7.2 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-07-01 DOI: 10.1016/j.rec.2024.03.001
Albert Ariza-Solé , Francesc Formiga , David Monterde , Emili Vela , Elena Calvo , Josep Comín-Colet
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引用次数: 0
Once weekly semaglutide and cardiovascular outcomes in patients with type 2 diabetes and heart failure with reduced left ventricular ejection fraction 2型糖尿病合并左心室射血分数减低的心力衰竭患者每周一次的塞马鲁肽与心血管预后。
IF 7.2 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-07-01 DOI: 10.1016/j.rec.2023.12.008
Miguel A. Pérez-Velasco , Alicia Trenas , M. Rosa Bernal-López , María D. García de Lucas , Ricardo Gómez-Huelgas , Luis M. Pérez-Belmonte
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引用次数: 0
Dual SGLT1 and SGLT2 inhibition: more than the sum of its parts SGLT1 和 SGLT2 双重抑制:超越各部分的总和。
IF 7.2 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-07-01 DOI: 10.1016/j.rec.2024.01.011
Enrique Sánchez-Muñoz , Juan Antonio Requena-Ibáñez , Juan José Badimón
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引用次数: 0
Fontan-associated liver disease after heart transplant 心脏移植后的丰坦相关肝病。
IF 7.2 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2024-07-01 DOI: 10.1016/j.rec.2023.11.020
Inés Ponz de Antonio , Pilar Castillo Grau , Ángel Aroca Peinado
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引用次数: 0
期刊
Revista española de cardiología (English ed.)
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