首页 > 最新文献

Archives of Oral and Maxillofacial Surgery最新文献

英文 中文
Facial Burns: A One Year Audit at a Tertiary Hospital in Dar Es Salaam, Tanzania 面部烧伤:坦桑尼亚达累斯萨拉姆一家三级医院的一年审计
Pub Date : 2021-08-09 DOI: 10.36959/379/368
K. Sohal, E. Simon, Kalyanyama Boniphace, Deoglas David, Sira, Stanslaus Owibingire, Moshy Jeremiah Robert
Background: Facial burn injuries have plagued mankind since time immemorial and till the present day, they remain among the major public health problems. Since the face carries the identity of an individual, it is the most psychologically significant area of the body. Therefore, any disfigurement to the face such as that caused by burns has potential psychosocial consequences to the victim. The present study aimed at determining the etiology, pattern of occurrence and management of facial burns among patients attended at Muhimbili National Hospital, Dar es Salaam Tanzania. Material and Methods: This was a one-year prospective study of all consecutive patients with facial burns who attended treatment at the Muhimbili National Hospital (MNH). The variables examined included socio-demographic characteristics, etiology, clinical features and management of facial burns. The data were analyzed using SPSS software for windows version 23 (IBM Corporation Chicago, IL, USA). Fisher’s t-test was used and associations were considered significant when p < 0.05. Results: A total of 112 patients with body burn injuries were attended during the period of this study where by 29.5% of the patients had burn injuries to the facial region. The male to female ratio was 2:1 and patient’s age ranged from 17 to 70 years, with a mean age of 30.6 (SD 12.3) years. The etiological factors included open fire that affected (78.8%) of the patients followed by scalding (12.1%) and electricity (9.1%). Majority (81.8%) of the burn injuries were accidental in nature. The most frequently burnt facial aesthetic zones were the zygomatic region followed by the orbits. More than 80% of the participants had complications where by hypo-pigmentation was the commonest (51%) complication of burn injuries encountered. Conclusion: Facial burns affected males twice more than females. Open fire was the most common etiological factor and the zygoma was the most frequently affected facial esthetic zone. Majority of the patients had complications due to burn injury, of which the facial skin hypo-pigmentation was the commonest followed by death.
面部烧伤自古以来一直困扰着人类,直到今天,它们仍然是主要的公共卫生问题之一。因为脸承载着一个人的身份,所以它是身体上最重要的心理区域。因此,面部的任何毁容,如烧伤造成的毁容,都会对受害者造成潜在的社会心理后果。本研究旨在确定坦桑尼亚达累斯萨拉姆Muhimbili国立医院就诊患者面部烧伤的病因、发生模式和处理。材料和方法:这是一项为期一年的前瞻性研究,纳入了在Muhimbili国立医院(MNH)接受治疗的所有连续面部烧伤患者。检查的变量包括社会人口学特征、病因、临床特征和面部烧伤的处理。使用SPSS软件(IBM Corporation Chicago, IL, USA)对数据进行分析。采用Fisher’s t检验,当p < 0.05时认为相关性显著。结果:本研究共收治112例全身烧伤患者,其中面部烧伤占29.5%。男女比例2:1,患者年龄17 ~ 70岁,平均年龄30.6岁(SD 12.3)。病因以明火为主(78.8%),其次为烫伤(12.1%)和电伤(9.1%)。绝大多数(81.8%)为意外烧伤。面部烧伤最常见的美容区是颧骨区,其次是眼眶。超过80%的参与者有并发症,其中色素沉着减少是烧伤最常见的并发症(51%)。结论:男性面部烧伤发生率是女性的2倍。明火是最常见的病因,颧骨是最常受影响的面部美容区。大多数患者出现烧伤并发症,其中以面部皮肤色素沉着最常见,其次为死亡。
{"title":"Facial Burns: A One Year Audit at a Tertiary Hospital in Dar Es Salaam, Tanzania","authors":"K. Sohal, E. Simon, Kalyanyama Boniphace, Deoglas David, Sira, Stanslaus Owibingire, Moshy Jeremiah Robert","doi":"10.36959/379/368","DOIUrl":"https://doi.org/10.36959/379/368","url":null,"abstract":"Background: Facial burn injuries have plagued mankind since time immemorial and till the present day, they remain among the major public health problems. Since the face carries the identity of an individual, it is the most psychologically significant area of the body. Therefore, any disfigurement to the face such as that caused by burns has potential psychosocial consequences to the victim. The present study aimed at determining the etiology, pattern of occurrence and management of facial burns among patients attended at Muhimbili National Hospital, Dar es Salaam Tanzania. Material and Methods: This was a one-year prospective study of all consecutive patients with facial burns who attended treatment at the Muhimbili National Hospital (MNH). The variables examined included socio-demographic characteristics, etiology, clinical features and management of facial burns. The data were analyzed using SPSS software for windows version 23 (IBM Corporation Chicago, IL, USA). Fisher’s t-test was used and associations were considered significant when p < 0.05. Results: A total of 112 patients with body burn injuries were attended during the period of this study where by 29.5% of the patients had burn injuries to the facial region. The male to female ratio was 2:1 and patient’s age ranged from 17 to 70 years, with a mean age of 30.6 (SD 12.3) years. The etiological factors included open fire that affected (78.8%) of the patients followed by scalding (12.1%) and electricity (9.1%). Majority (81.8%) of the burn injuries were accidental in nature. The most frequently burnt facial aesthetic zones were the zygomatic region followed by the orbits. More than 80% of the participants had complications where by hypo-pigmentation was the commonest (51%) complication of burn injuries encountered. Conclusion: Facial burns affected males twice more than females. Open fire was the most common etiological factor and the zygoma was the most frequently affected facial esthetic zone. Majority of the patients had complications due to burn injury, of which the facial skin hypo-pigmentation was the commonest followed by death.","PeriodicalId":385193,"journal":{"name":"Archives of Oral and Maxillofacial Surgery","volume":"06 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131220541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of the Success of Oral Rehabilitation of Patients with with Teeth Loss and Class III Skeletal Malocclusion 牙缺失及III类骨错牙合患者口腔康复效果评价
Pub Date : 2021-07-28 DOI: 10.36959/379/367
G. Hakobyan, L. Khachatryan, G. Khachatryan, Gegham Tunyan, Haruthyunyan Armen
Objective: The objective of the study is to assess treatment success of teeth loss patients with class III skeletal malocclusion through a multidisciplinary approach, including orthognathic surgery and implant prosthetic rehabilitation. Materials and Methods: The present retrospective study aimed at investigating the 5-year clinical treatments outcomes 16 patients with class III malocclusion and teeth loss. Clinical, laboratory, radiological methods were used in the examination of patients. Surgical stage included sagittal bilateral osteotomy of the lower jaw and reposition it back, Le Fort I osteotomy, 7-8 months after the orthognathic surgery 132 implants were inserted. After 2 to 4 months of submerged healing period patients had received implant-fixed prostheses. Results: No serious intraoperative or immediate postoperative complications were noted. At the control examination after 6 months after surgery, an X-ray examination we did not observe any clinical or radiological signs of inflammation in the area of osteotomy sites and titanium mini plates. Success rate of implants 5 years after was 96.2%. Conclusion: After orthognathic surgery and dental implant prosthetic rehabilitation, the masticatory function, esthetics of the facial profile and occlusion was improved. Patients expressed satisfaction with the result of treatment and improved quality of life.
目的:本研究的目的是通过多学科的方法,包括正颌手术和种植修复康复,评估III类骨骼错颌缺牙患者的治疗成功率。材料与方法:回顾性分析16例III类错牙合缺失患者5年的临床治疗效果。采用临床、实验室、放射学等方法对患者进行检查。手术分期包括双侧下颌矢状面截骨并复位,Le Fort I型截骨术,正颌手术后7-8个月植入种植体132枚。2 ~ 4个月的浸没愈合期后,患者接受种植固定假体。结果:术中、术后均无严重并发症。在术后6个月的对照检查中,x线检查我们未观察到截骨部位和迷你钛板区域的任何临床或放射学炎症迹象。5年后种植成功率为96.2%。结论:经正颌手术和种植义齿康复治疗后,咀嚼功能、面部轮廓和咬合美观均有改善。患者对治疗结果和生活质量的改善表示满意。
{"title":"Assessment of the Success of Oral Rehabilitation of Patients with with Teeth Loss and Class III Skeletal Malocclusion","authors":"G. Hakobyan, L. Khachatryan, G. Khachatryan, Gegham Tunyan, Haruthyunyan Armen","doi":"10.36959/379/367","DOIUrl":"https://doi.org/10.36959/379/367","url":null,"abstract":"Objective: The objective of the study is to assess treatment success of teeth loss patients with class III skeletal malocclusion through a multidisciplinary approach, including orthognathic surgery and implant prosthetic rehabilitation. Materials and Methods: The present retrospective study aimed at investigating the 5-year clinical treatments outcomes 16 patients with class III malocclusion and teeth loss. Clinical, laboratory, radiological methods were used in the examination of patients. Surgical stage included sagittal bilateral osteotomy of the lower jaw and reposition it back, Le Fort I osteotomy, 7-8 months after the orthognathic surgery 132 implants were inserted. After 2 to 4 months of submerged healing period patients had received implant-fixed prostheses. Results: No serious intraoperative or immediate postoperative complications were noted. At the control examination after 6 months after surgery, an X-ray examination we did not observe any clinical or radiological signs of inflammation in the area of osteotomy sites and titanium mini plates. Success rate of implants 5 years after was 96.2%. Conclusion: After orthognathic surgery and dental implant prosthetic rehabilitation, the masticatory function, esthetics of the facial profile and occlusion was improved. Patients expressed satisfaction with the result of treatment and improved quality of life.","PeriodicalId":385193,"journal":{"name":"Archives of Oral and Maxillofacial Surgery","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131752106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does COVID-19 Disease Affect Dental Implant Success Rate? COVID-19疾病会影响种植成功率吗?
Pub Date : 2021-07-24 DOI: 10.36959/379/366
Ismayilov Orkhan, Ekemen Ali, Alpay Hakan
COVID-19 pandemics, spreading rapidly all over the world continues to affect the world even though vaccines are being applied [1]. The authors of this study recently observed that the dental implant success rates decrease in patients with COVID-19 disease after dental implant surgery. In a group of 14 patients, 85 dental implants were placed, and 4 of the implants were failed. It was observed that all the patients with failed implants had a positive COVID-19 test 4-6 weeks after the surgery. Six of the 14 patients were affected by COVID-19 and 4 out of 42 implants applied to these patients were failed. All implants were placed by the same surgeon using the same brand of an implant with appropriate primary stability. Only one of these patients had pain during the recovery period, but all other 5 patients with implant failure have no symptoms. Radiological examination reveals neck resorption in only one of the 4 failed implants. This situation brought to the mind of the authors that COVID-19 disease could have negative effects on osteointegration and the success rate of dental implant surgery. After a review of the recent literature, clinically similar results were explained, stating COVID-19 disease may negatively affect bone osseointegration [2].
尽管正在使用疫苗,但在全球迅速蔓延的COVID-19大流行继续影响着世界[1]。该研究的作者最近观察到,COVID-19患者在种植牙手术后种植成功率下降。在14例患者中,放置了85颗种植体,其中4颗种植体失败。术后4-6周,所有种植失败患者的COVID-19检测均呈阳性。14例患者中有6例感染新冠病毒,42例植入物中有4例失败。所有植入物由同一位外科医生使用同一品牌的植入物放置,具有适当的初始稳定性。其中只有1例患者在康复期间出现疼痛,其他5例种植体失败患者均无症状。放射学检查显示4个失败植入物中只有1个颈部吸收。这种情况使作者想到COVID-19疾病可能对骨整合和种植牙手术成功率产生负面影响。经过对近期文献的回顾,临床上类似的结果得到了解释,表明COVID-19疾病可能对骨骨整合产生负面影响[2]。
{"title":"Does COVID-19 Disease Affect Dental Implant Success Rate?","authors":"Ismayilov Orkhan, Ekemen Ali, Alpay Hakan","doi":"10.36959/379/366","DOIUrl":"https://doi.org/10.36959/379/366","url":null,"abstract":"COVID-19 pandemics, spreading rapidly all over the world continues to affect the world even though vaccines are being applied [1]. The authors of this study recently observed that the dental implant success rates decrease in patients with COVID-19 disease after dental implant surgery. In a group of 14 patients, 85 dental implants were placed, and 4 of the implants were failed. It was observed that all the patients with failed implants had a positive COVID-19 test 4-6 weeks after the surgery. Six of the 14 patients were affected by COVID-19 and 4 out of 42 implants applied to these patients were failed. All implants were placed by the same surgeon using the same brand of an implant with appropriate primary stability. Only one of these patients had pain during the recovery period, but all other 5 patients with implant failure have no symptoms. Radiological examination reveals neck resorption in only one of the 4 failed implants. This situation brought to the mind of the authors that COVID-19 disease could have negative effects on osteointegration and the success rate of dental implant surgery. After a review of the recent literature, clinically similar results were explained, stating COVID-19 disease may negatively affect bone osseointegration [2].","PeriodicalId":385193,"journal":{"name":"Archives of Oral and Maxillofacial Surgery","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122633785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effects of Particulate Dentine Compared to Bio-Oss® on Bone Regeneration 颗粒牙本质与Bio-Oss®对骨再生的影响
Pub Date : 2021-06-30 DOI: 10.36959/379/364
Habashneh Rola Al, A. Mohammad, Hammad Huda, A. Sawsan, Karadsheh Omar, Alshami Raed
A total of 32 male Sprague Dawley rats were subjected to a surgical creation of a calvarial defect of a 5 mm diameter. The rats were divided into 4 groups of 8 rats. The first group received no graft material in the defect and was named the control group. The 2nd group received human particulate dentine. The 3rd group received a mixture of human particulate dentine and Bio-Oss®.
共有32只雄性斯普拉格·道利大鼠接受了5毫米直径颅骨缺损的手术治疗。将大鼠分为4组,每组8只。第一组在缺损处不移植材料,命名为对照组。第二组注射人牙本质颗粒。第三组接受人牙本质颗粒和Bio-Oss®的混合物。
{"title":"The Effects of Particulate Dentine Compared to Bio-Oss® on Bone Regeneration","authors":"Habashneh Rola Al, A. Mohammad, Hammad Huda, A. Sawsan, Karadsheh Omar, Alshami Raed","doi":"10.36959/379/364","DOIUrl":"https://doi.org/10.36959/379/364","url":null,"abstract":"A total of 32 male Sprague Dawley rats were subjected to a surgical creation of a calvarial defect of a 5 mm diameter. The rats were divided into 4 groups of 8 rats. The first group received no graft material in the defect and was named the control group. The 2nd group received human particulate dentine. The 3rd group received a mixture of human particulate dentine and Bio-Oss®.","PeriodicalId":385193,"journal":{"name":"Archives of Oral and Maxillofacial Surgery","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122162115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Recreating the Face - A Mini-Review of Current Studies on 3D Bioprinting in Oral and Maxillofacial Surgery 重塑面部-口腔颌面外科3D生物打印研究现状综述
Pub Date : 2020-12-31 DOI: 10.36959/379/360
Sen Rwik
According to the United States National Institute of Dental and Craniofacial Research, craniofacial anomalies are the most common birth defects. Genetic, epigenetic, and environmental causes lead to craniofacial anomalies which can range from cleft lip and palate to major defects in the development of the skull, face, brain, eyes, ears, and nose. Oral and maxillofacial surgeries are performed on individuals with craniofacial defects, but success of surgery is dependent on nature of the defect. Some defects are too complex which need multiple surgeries, but still not be completely cured by traditional methods. In this direction, 3 dimensional or 3D bioprinting has emerged as a promising modern technology that can significantly benefit the field. A personalized medicine approach to address craniofacial defects is provided by 3D-printing technologies which integrate doctors, engineers and researchers to work for a common goal [1]. Hence, this mini review of literature on 3D bioprinting discusses the technology in the context of craniofacial, and hence oral and maxillofacial therapeutics. In the field of oral and maxillofacial therapeutics, researchers and surgeons are aiming to develop a 3D scaffold by direct 3D printing technology to fabricate complicated tissue grafts. They need to possess all the necessary biological properties and environment for cell division and tissue regeneration. Hence, the current and future challenges of 3D bioprinting will be to achieve the above criteria is a cost-effective and timely manner. Check for updates significantly convenient, greatly improves their outcome, and enhances the quality of life of patients [5]. The Process of 3D Bioprinting The process of 3D bioprinting can be categorized into pre-bioprinting, bioprinting, and post-bioprinting [6-8]. At the very beginning, suitable cells for synthesizing the bioink are isolated and cultured to obtain a large amount of viable starting material. In the pre-bioprinting step, imaging is performed on the tissue that will be bioprinted. The imaging is done by technology like Computed tomography (CT) or cone beam CT in Digital Imaging and Communications in Medicine (DICOM) format and magnetic resonance [6,8,9]. Standard Triangle Language (STL) format is used to provide the image as input to the bioprinter [6,8,9]. Hence, a Computer Aided Design (CAD) model of the target tissue is obtained [6]. Introduction 3D bioprinting has addressed the problems associated with traditional surgeries and therapy. The emergence of 3D printing technology occurred in the 1990’s when synthetic inks were used to generate fabricating scaffolds, leading up to the invention of bioprinting in the 21st century [2]. Bioprinting employs bioinks which are composed of biocompatible substances made of cells or matrices derived from natural sources which have applications in tissue engineering [3,4]. The technology evolved from additive manufacturing where biomaterials are used to develop scaffolds whic
根据美国国家牙科和颅面研究所的研究,颅面畸形是最常见的出生缺陷。遗传、表观遗传和环境因素导致颅面畸形,其范围从唇裂和腭裂到颅骨、面部、大脑、眼睛、耳朵和鼻子发育的重大缺陷。口腔和颌面手术是对颅面缺陷的个体进行的,但手术的成功取决于缺陷的性质。有些缺损过于复杂,需要多次手术治疗,但传统方法仍不能完全治愈。在这个方向上,三维或3D生物打印已经成为一项有前途的现代技术,可以显着使该领域受益。3d打印技术为解决颅面缺陷提供了一种个性化的医疗方法,该技术将医生、工程师和研究人员整合在一起,为共同的目标而努力。因此,这篇关于3D生物打印的文献综述讨论了该技术在颅面、口腔和颌面治疗方面的应用。在口腔颌面治疗领域,研究人员和外科医生的目标是通过直接3D打印技术开发3D支架来制造复杂的组织移植物。它们需要具备细胞分裂和组织再生所需的所有生物学特性和环境。因此,3D生物打印当前和未来的挑战将是如何以符合成本效益和及时的方式实现上述标准。检查更新非常方便,大大改善了他们的预后,提高了患者的生活质量。生物3D打印的过程可分为生物预打印、生物打印和生物后打印[6-8]。首先,分离和培养适合合成生物链接的细胞,以获得大量有活力的起始材料。在预生物打印步骤中,对将要进行生物打印的组织进行成像。成像是通过计算机断层扫描(CT)或医学数字成像和通信(DICOM)格式的锥束CT和磁共振等技术完成的[6,8,9]。标准三角语言(STL)格式用于提供图像作为生物打印机的输入[6,8,9]。因此,获得了目标组织的计算机辅助设计(CAD)模型。3D生物打印解决了传统手术和治疗相关的问题。3D打印技术的出现发生在20世纪90年代,当时合成油墨被用于制造支架,导致了21世纪生物打印的发明。生物打印采用生物墨水,这种墨水由天然来源的细胞或基质制成的生物相容性物质组成,在组织工程中有应用[3,4]。该技术是从增材制造发展而来的,在增材制造中,生物材料被用来开发精确适合颅面缺陷尺寸的支架(图1)。3D生物打印在口腔和颌面外科中有几个优点,因为传统的方法如植骨并不总是方便的。这是因为来自不同祖干细胞的几种不同种类的骨骼和软骨被复杂地组织起来形成颅面骨骼。在这个方向上,3D生物打印极大地改善了颅面外科领域,因为它允许选择特定种类的细胞来生物打印目标组织。3D生物打印的另一个非常重要的优势是颅面手术的成功不再仅仅取决于外科医生。此外,3D打印通过在假体中再现患者目标组织的物理和美学特性,采用了个性化的治疗方法,这在早期是劳动密集型的。因此,生物3D打印使得口腔颌面外科手术过程变得更加复杂。引文:Sen R(2020)再造面部——口腔颌面外科生物3D打印研究现状综述。档案口腔颌面外科手术3(1):86-89 Sen.档案口腔颌面外科手术2020,3(1):86-89开放获取|页87 |用于3D生物打印,其中生物材料以图案层铺设以达到最终构象[11]。最近一项关于颌面外科3D生物打印的综述报告了来自35个国家的297份出版物,其中2889名患者的预后因使用3D生物打印而得到改善。这些出版物表明,最多的临床指征发生牙种植和重建下颌骨bbb。总体而言,3D生物打印技术提高了手术精度,缩短了手术时间,但成本高,生产时间长仍然是缺点。 生物3D打印在颅面外科的进一步应用包括创伤外科、正颌外科、面部修复、颞下颌关节(TMJ)和复杂面部重建[13-18]。3D生物打印在上述领域显示出几个好处。在创伤外科中,3D打印钛网用于治疗因眶壁重建效率低下导致的术后内陷或复视。3D生物打印解决了眼窝底和眼窝壁爆裂性骨折造成的问题。3D生物打印有助于在正颌手术期间进行精确诊断。与传统假肢相比,3D生物打印有几个优点。TMJ重建中的一个常见问题是自旋,这是TMJ髁突和窝的不稳定,影响上颌骨的正确放置。个性化正颌手术引导(POSG)系统使用3D生物打印[19]帮助解决了这一问题。生物3D打印在复杂面部重建中的优势包括钢板适配准确、骨采集精确、骨-板距离和出血量小、手术和麻醉时间短[13,20]。Devid Zille博士在他的文章中广泛讨论了3D生物打印的含义。Zille博士领导Osteomed的患者特异性植入计划,Osteomed是世界上最大的用于颌面、神经和四肢手术的小骨植入制造商之一。生物打印过程使用装载在打印机墨盒[6]上的由细胞、营养物质和基质制成的生物墨水,对前一步中获得的组织图像进行一层又一层的打印。生物打印的基于细胞的实体被称为预组织,它被移到培养箱中成熟[10]。成熟后,细胞以一层又一层的方式连续分配到生物相容性支架上,从而形成类似组织[6]的3D生物结构。生物后打印有助于开发和维持3D结构[8]的机械稳定性和功能。生物打印实体中的细胞需要机械和化学信号来重塑和发展组织,以实现结构的适当可持续性。在这个方向上,生物反应器为组织的存活、成熟和血管化提供了理想的环境和模拟[6,7]。在口腔、颌面和面部重建手术中,生物3D打印技术包括某些标准,如开发面部解剖原型,改善手术后面部轮廓对称性,生物打印预轮廓移植物,为有疤痕、不对称和畸形的患者开发高质量的假体。3D生物打印技术在外科手术中的另一个应用领域是为医学生开发先进的模拟模型。使用CT和磁共振成像(MRI)等成像技术,解剖扫描被准备并保存为DICOM等标准格式。接下来,使用CAD软件用STL生成虚拟三维原型图1:3D生物打印示意图。受损组织通过CAD成像,然后使用源自细胞和其他因素的生物墨水对图像进行生物打印。接下来,生物打印组织通过手术植入患者体内,作为修复、重建、再生或修复的治疗手段。引用本文:Sen R(2020)再造面部——口腔颌面外科3D生物打印研究现状综述。结论:虽然目前3D生物打印技术已经取得了很大的成功和前景,但要想大规模应用于患者,仍需要相当大的发展。需要进一步的研究将其应用于更广泛的治疗方法。尽管如此,3D生物打印已经在口腔颌面外科的重建、修复和假体方面取得了成功。干细胞研究的进步、卓越的工程和计算技术将进一步推进这项优雅的技术。在监管层面,需要注意确保这项技术的适当管理、可负担性、可获得性和健康保险的适用性。
{"title":"Recreating the Face - A Mini-Review of Current Studies on 3D Bioprinting in Oral and Maxillofacial Surgery","authors":"Sen Rwik","doi":"10.36959/379/360","DOIUrl":"https://doi.org/10.36959/379/360","url":null,"abstract":"According to the United States National Institute of Dental and Craniofacial Research, craniofacial anomalies are the most common birth defects. Genetic, epigenetic, and environmental causes lead to craniofacial anomalies which can range from cleft lip and palate to major defects in the development of the skull, face, brain, eyes, ears, and nose. Oral and maxillofacial surgeries are performed on individuals with craniofacial defects, but success of surgery is dependent on nature of the defect. Some defects are too complex which need multiple surgeries, but still not be completely cured by traditional methods. In this direction, 3 dimensional or 3D bioprinting has emerged as a promising modern technology that can significantly benefit the field. A personalized medicine approach to address craniofacial defects is provided by 3D-printing technologies which integrate doctors, engineers and researchers to work for a common goal [1]. Hence, this mini review of literature on 3D bioprinting discusses the technology in the context of craniofacial, and hence oral and maxillofacial therapeutics. In the field of oral and maxillofacial therapeutics, researchers and surgeons are aiming to develop a 3D scaffold by direct 3D printing technology to fabricate complicated tissue grafts. They need to possess all the necessary biological properties and environment for cell division and tissue regeneration. Hence, the current and future challenges of 3D bioprinting will be to achieve the above criteria is a cost-effective and timely manner. Check for updates significantly convenient, greatly improves their outcome, and enhances the quality of life of patients [5]. The Process of 3D Bioprinting The process of 3D bioprinting can be categorized into pre-bioprinting, bioprinting, and post-bioprinting [6-8]. At the very beginning, suitable cells for synthesizing the bioink are isolated and cultured to obtain a large amount of viable starting material. In the pre-bioprinting step, imaging is performed on the tissue that will be bioprinted. The imaging is done by technology like Computed tomography (CT) or cone beam CT in Digital Imaging and Communications in Medicine (DICOM) format and magnetic resonance [6,8,9]. Standard Triangle Language (STL) format is used to provide the image as input to the bioprinter [6,8,9]. Hence, a Computer Aided Design (CAD) model of the target tissue is obtained [6]. Introduction 3D bioprinting has addressed the problems associated with traditional surgeries and therapy. The emergence of 3D printing technology occurred in the 1990’s when synthetic inks were used to generate fabricating scaffolds, leading up to the invention of bioprinting in the 21st century [2]. Bioprinting employs bioinks which are composed of biocompatible substances made of cells or matrices derived from natural sources which have applications in tissue engineering [3,4]. The technology evolved from additive manufacturing where biomaterials are used to develop scaffolds whic","PeriodicalId":385193,"journal":{"name":"Archives of Oral and Maxillofacial Surgery","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130902590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Case of Peripheral Ameloblastic Fibroma: Case Report 外周成釉纤维瘤1例报告
Pub Date : 2020-06-10 DOI: 10.36959/379/352
Kim Sang Woo, S. Keith, Luo Minou, P. Jason
Ameloblastic fibroma (AF) is an uncommon mixed benign odontogenic tumor that usually presents in the first two decades of life with no predilection for sex or race. It can present either peripherally or centrally with a majority of the cases presenting in the posterior mandible. Although it usually presents in posterior mandible, we present a case of a peripheral AF in the maxillary anterior gingiva, which has been described rarely in literature. Described are the clinical, radiographic and histologic features and the subsequent surgical treatment for this lesion.
成釉细胞纤维瘤(AF)是一种罕见的混合良性牙源性肿瘤,通常出现在生命的前二十岁,没有性别或种族的偏好。它可以出现在周围或中央大多数情况下出现在后下颌骨。虽然它通常出现在下颌骨后,我们提出了一例周围心房颤动在上颌前龈,这在文献中很少被描述。本文描述了该病变的临床、影像学和组织学特征以及随后的手术治疗。
{"title":"A Rare Case of Peripheral Ameloblastic Fibroma: Case Report","authors":"Kim Sang Woo, S. Keith, Luo Minou, P. Jason","doi":"10.36959/379/352","DOIUrl":"https://doi.org/10.36959/379/352","url":null,"abstract":"Ameloblastic fibroma (AF) is an uncommon mixed benign odontogenic tumor that usually presents in the first two decades of life with no predilection for sex or race. It can present either peripherally or centrally with a majority of the cases presenting in the posterior mandible. Although it usually presents in posterior mandible, we present a case of a peripheral AF in the maxillary anterior gingiva, which has been described rarely in literature. Described are the clinical, radiographic and histologic features and the subsequent surgical treatment for this lesion.","PeriodicalId":385193,"journal":{"name":"Archives of Oral and Maxillofacial Surgery","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132269395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Patient with a "Strawberry Tongue" 有“草莓舌头”的病人
Pub Date : 2019-04-25 DOI: 10.36959/379/350
G. James
The primary constituents of saliva are water and mucins that keep the oral mucous membranes moist and lubricated. When salivary gland secretions are diminished or lost, patients may develop symptoms of oral dryness (xerostomia), burning, soreness, and difficulty with eating, taste, and swallowing. The use of xerogenic medications is one of the major causes of reduced salivary gland function. This case report describes a patient with mood disorders and fibromyalgia for which he was taking five medications that are associated with xerostomia and hyposalivation. In order to alleviate his oral dryness, he began to use a homemade beverage that discolored his tongue and masked a median rhomboid glossitis. This lesion is a manifestation of infection by Candida albicans that can develop as a consequence of a loss of saliva and its constituent protective antimicrobial proteins.
唾液的主要成分是水和粘蛋白,它们保持口腔粘膜湿润和润滑。当唾液腺分泌物减少或消失时,患者可能出现口腔干燥(口干症)、灼烧、疼痛以及进食、味觉和吞咽困难等症状。使用致干性药物是导致唾液腺功能降低的主要原因之一。本病例报告描述了一位患有情绪障碍和纤维肌痛的患者,他正在服用五种与口干和唾液分泌减少有关的药物。为了缓解他的口腔干燥,他开始使用一种自制的饮料,使他的舌头变色,掩盖了中间菱形舌炎。这种病变是白色念珠菌感染的表现,可作为唾液及其组成保护性抗菌蛋白流失的结果而发展。
{"title":"A Patient with a \"Strawberry Tongue\"","authors":"G. James","doi":"10.36959/379/350","DOIUrl":"https://doi.org/10.36959/379/350","url":null,"abstract":"The primary constituents of saliva are water and mucins that keep the oral mucous membranes moist and lubricated. When salivary gland secretions are diminished or lost, patients may develop symptoms of oral dryness (xerostomia), burning, soreness, and difficulty with eating, taste, and swallowing. The use of xerogenic medications is one of the major causes of reduced salivary gland function. This case report describes a patient with mood disorders and fibromyalgia for which he was taking five medications that are associated with xerostomia and hyposalivation. In order to alleviate his oral dryness, he began to use a homemade beverage that discolored his tongue and masked a median rhomboid glossitis. This lesion is a manifestation of infection by Candida albicans that can develop as a consequence of a loss of saliva and its constituent protective antimicrobial proteins.","PeriodicalId":385193,"journal":{"name":"Archives of Oral and Maxillofacial Surgery","volume":"81 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122898445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enucleation of a Rare Hybrid Odontogenic Lesion in the Anterior Maxilla of a 10-Year-Old Boy 1例10岁男童前上颌罕见混合型牙源性病变的去核
Pub Date : 2019-04-20 DOI: 10.36959/379/349
Gruza Amanda, C. Jason, C. Curtis, Abomr Diplomat, Catherine, Abomp Diplomat
Hybrid odontogenic lesions are a well-recognized phenomenon. They most often show features of various odontogenic neoplasms arising within cyst-like structures. The etiopathogenesis of hybrid odontogenic lesions is not well defined, however, the presence of numerous, closely approximated sources of pluripotent epithelial cells in the developing jaws is likely associated with their development. This case highlights an interesting mixed radiolucent and radiopaque, expansile cystic lesion with a follicular relationship to an unerupted tooth in a young child. Histologically, the lesion showed a combination of dentigerous cyst, calcifying odontogenic cyst and adenomatoid odontogenic tumor. Close radiographic proximity of the hybrid odontogenic lesion to a focal expansion of the gubernacular canal suggests that the adenomatoid odontogenic tumor portion of the hybrid lesion may have arisen directly from this structure, resulting in delayed eruption of the adjacent tooth and subsequent development of a dentigerous cyst with foci of calcifying odontogenic cyst. Complete enucleation of the cystic structure with retention of the associated tooth was performed, with a 6-month follow-up showing complete healing of the surgical site and no evidence of recurrence of the cystic lesion. To date, there have been only six reported cases of lesions with features of both calcifying odontogenic cyst and adenomatoid odontogenic tumor. The current case represents the first documented case of a dentigerous cyst with foci of both calcifying odontogenic cyst and adenomatoid odontogenic tumor. Given the variable nature and biological behavior of the odontogenic entities that compose hybrid odontogenic lesions, unusual clinical presentations and unexpected progression are possible. Further documentation of such hybrid lesions is necessary to fully elucidate how these entities behave clinically, radiographically and pathologically.
混合牙源性病变是一种公认的现象。它们通常表现为出现在囊肿样结构内的各种牙源性肿瘤的特征。杂合性牙源性病变的发病机制尚不明确,然而,发育中的颌骨中存在大量接近的多能性上皮细胞来源,可能与它们的发育有关。这个病例突出了一个有趣的混合放射透明和放射不透明,扩张囊性病变与滤泡关系的未出牙的幼儿。组织学表现为含牙囊肿、钙化性牙源性囊肿和腺瘤样牙源性肿瘤的组合。杂交牙源性病变的近距离x线摄影显示,杂交牙源性病变的腺瘤样牙源性肿瘤部分可能直接来自于这种结构,导致邻近牙齿的延迟爆发和随后的牙源性囊肿的发展,并伴有病灶钙化牙源性囊肿。完成囊性结构的完全去核并保留相关牙齿,6个月的随访显示手术部位完全愈合,没有囊性病变复发的证据。迄今为止,仅有6例报告的病变同时具有钙化性牙源性囊肿和腺瘤样牙源性肿瘤的特征。本病例是第一例同时伴有钙化性牙源性囊肿和腺瘤样牙源性肿瘤的牙源性囊肿。考虑到构成混合型牙源性病变的牙源性实体的可变性质和生物学行为,不寻常的临床表现和意想不到的进展是可能的。为了充分阐明这些实体在临床、放射学和病理学上的表现,有必要进一步记录这种混合型病变。
{"title":"Enucleation of a Rare Hybrid Odontogenic Lesion in the Anterior Maxilla of a 10-Year-Old Boy","authors":"Gruza Amanda, C. Jason, C. Curtis, Abomr Diplomat, Catherine, Abomp Diplomat","doi":"10.36959/379/349","DOIUrl":"https://doi.org/10.36959/379/349","url":null,"abstract":"Hybrid odontogenic lesions are a well-recognized phenomenon. They most often show features of various odontogenic neoplasms arising within cyst-like structures. The etiopathogenesis of hybrid odontogenic lesions is not well defined, however, the presence of numerous, closely approximated sources of pluripotent epithelial cells in the developing jaws is likely associated with their development. This case highlights an interesting mixed radiolucent and radiopaque, expansile cystic lesion with a follicular relationship to an unerupted tooth in a young child. Histologically, the lesion showed a combination of dentigerous cyst, calcifying odontogenic cyst and adenomatoid odontogenic tumor. Close radiographic proximity of the hybrid odontogenic lesion to a focal expansion of the gubernacular canal suggests that the adenomatoid odontogenic tumor portion of the hybrid lesion may have arisen directly from this structure, resulting in delayed eruption of the adjacent tooth and subsequent development of a dentigerous cyst with foci of calcifying odontogenic cyst. Complete enucleation of the cystic structure with retention of the associated tooth was performed, with a 6-month follow-up showing complete healing of the surgical site and no evidence of recurrence of the cystic lesion. To date, there have been only six reported cases of lesions with features of both calcifying odontogenic cyst and adenomatoid odontogenic tumor. The current case represents the first documented case of a dentigerous cyst with foci of both calcifying odontogenic cyst and adenomatoid odontogenic tumor. Given the variable nature and biological behavior of the odontogenic entities that compose hybrid odontogenic lesions, unusual clinical presentations and unexpected progression are possible. Further documentation of such hybrid lesions is necessary to fully elucidate how these entities behave clinically, radiographically and pathologically.","PeriodicalId":385193,"journal":{"name":"Archives of Oral and Maxillofacial Surgery","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128506734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Postoperative Wound Infection in Major Head and Neck Oncological Surgery: Does Antibiotic Prophylaxis Have an Influence? 头颈部肿瘤大手术术后伤口感染:抗生素预防有影响吗?
Pub Date : 2018-06-07 DOI: 10.36959/379/348
D. Dequanter, Alexandra Rodríguez, R. Javadian
A total of 14 of the 90 patients (16%) developed a postoperative wound infection after major oncological head and neck surgery during the study period. Of these patients, all developed pharyngocutaneous fistulas (PCF). All the patients received initially empiric antibiotics which were modified following results of culture and sensitivity of the samples. The time to infection post-operatively ranged from 2 days to 21 days. The most common organism isolated from clinical specimens was methicillin-resistant Staphylococcus aureus.
在研究期间,90例患者中有14例(16%)在重大肿瘤性头颈部手术后发生术后伤口感染。所有患者均出现咽皮瘘(PCF)。所有患者最初均使用经验性抗生素,根据培养结果和样品敏感性进行修改。术后至感染时间为2 ~ 21天。从临床标本中分离出的最常见的细菌是耐甲氧西林金黄色葡萄球菌。
{"title":"Postoperative Wound Infection in Major Head and Neck Oncological Surgery: Does Antibiotic Prophylaxis Have an Influence?","authors":"D. Dequanter, Alexandra Rodríguez, R. Javadian","doi":"10.36959/379/348","DOIUrl":"https://doi.org/10.36959/379/348","url":null,"abstract":"A total of 14 of the 90 patients (16%) developed a postoperative wound infection after major oncological head and neck surgery during the study period. Of these patients, all developed pharyngocutaneous fistulas (PCF). All the patients received initially empiric antibiotics which were modified following results of culture and sensitivity of the samples. The time to infection post-operatively ranged from 2 days to 21 days. The most common organism isolated from clinical specimens was methicillin-resistant Staphylococcus aureus.","PeriodicalId":385193,"journal":{"name":"Archives of Oral and Maxillofacial Surgery","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128986455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Archives of Oral and Maxillofacial Surgery
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1