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Recent Research Advances in Biology Vol. 11最新文献

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Study on Revisiting Sacral Hiatus 重诊骶骨裂孔的研究
Pub Date : 2021-07-05 DOI: 10.9734/BPI/RRAB/V11/1780C
Rajani Singh
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引用次数: 0
Study on Adipocytes as Sensors of Lipid Transport through Caco-2/HT29-MTX Intestinal Barrier Rescued from Cancer Phenotype by Oleic Acid 油酸对Caco-2/HT29-MTX肠道屏障中脂质转运传感器的研究
Pub Date : 2021-07-05 DOI: 10.9734/BPI/RRAB/V11/10418D
E. Berger, A. Géloën
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引用次数: 0
Life as Interplay of Information and Matter 生命是信息和物质的相互作用
Pub Date : 2021-07-05 DOI: 10.9734/BPI/RRAB/V11/9291D
G. Battail
Any sequence can be transformed into an equivalent one by alphabet change and/or encoding. Thus an information cannot be identified to a single sequence, but should be defined as the equivalence class among sequences with respect to such transformations, an abstract entity. It may be represented by its ‘information message’ defined as the shortest binary sequence in this class, whose length quantitatively measures the information. Any sequence must be borne by a physical medium, so information bridges the abstract and the concrete. Perturbations in the physical world result in random symbol errors, while information may instruct the assembly of physical objects by the agency of the semantics it bears. Information theory tells that errorless communication is possible provided a long and redundant enough error-correcting code is used. Conserving genetic information over the ages needs error-correcting codes making the exact regeneration of genomes possible provided it is performed frequently enough. In engineering, such codes are conveniently defined by mathematical constraints which make the symbols mutually dependent, but constraints of any kind, defining ‘soft codes’, also do the job. The better conservation of old parts of the genome implies moreover that the genomic error-correcting codes are made of nested component codes. This scheme accounts for basic life features: need for successive generations, existence of discrete species with hierarchical taxonomy, trend of evolution towards increased complexity, etc. Transcription of the genes and their translation into polypeptidic chains, becoming proteins when properly folded, are controlled by enzymes, which as proteins are needed for their own synthesis. A feedback loop results, referred to as ‘semantic’ since it implements the genetic code which tells the meaning of the genes. Once closed, it keeps its structure, thereby conserving the genetic code. The onset of a new semantic feedback loop originates an organic code in Barbieri’s meaning, which itself induces a new soft component in the system of genomic nested error-correcting codes by imposing new constraints to the genome. Due to the feedback, constraints incurred by the proteins affect the genome. Besides the synthesis of proteins, the assembly of living structures, as instructed by the genome, involves interwoven semantic feedback loops. Although closed, they do not prevent the genome lengthening, say by horizontal genetic transfer, which increases both the information quantity, Corresponding author: Gérard Battail, Retired from E.N.S.T., Paris. E-mail: gb@gerard.battail.name. Life as Interplay of Information and Matter 174 hence its semantic specificity, and the redundancy, hence its error-correction ability. Thus, closing semantic feedback loops does not prevent evolution: new structures can be appended with improved resilience to errors. Regeneration failure is very infrequent and results in a widely different genome which originates
任何序列都可以通过字母变换和/或编码转换为等效序列。因此,一个信息不能被识别为单个序列,而应该被定义为序列之间的等价类,一个抽象的实体。它可以用它的“信息消息”来表示,定义为该类中最短的二进制序列,其长度定量地度量了信息。任何序列都必须由物理媒介承载,因此信息在抽象和具体之间架起了桥梁。物理世界中的扰动会导致随机的符号错误,而信息可以通过其承载的语义代理来指导物理对象的组装。信息论告诉我们,只要使用足够长的、冗余的纠错码,就有可能实现无差错通信。长久保存遗传信息需要纠错代码,只要频率足够高,精确的基因组再生就有可能实现。在工程中,这样的代码被方便地定义为数学约束,这使得符号相互依赖,但任何类型的约束,定义“软代码”,也可以完成这项工作。对基因组旧部分更好的保存意味着基因组纠错代码是由嵌套的成分代码组成的。该方案解释了基本的生命特征:需要连续世代,存在具有等级分类的离散物种,向增加复杂性的进化趋势等。基因的转录和翻译成多肽链,在适当折叠时变成蛋白质,是由酶控制的,而酶是蛋白质自身合成所需要的。一个反馈循环的结果,被称为“语义”,因为它实现了告诉基因意义的遗传密码。一旦关闭,它保持其结构,从而保存遗传密码。新的语义反馈循环的开始产生了Barbieri意义上的有机代码,该代码本身通过对基因组施加新的约束,在基因组嵌套纠错代码系统中诱导出新的软组件。由于反馈,蛋白质产生的约束会影响基因组。除了蛋白质的合成,生命结构的组装,按照基因组的指示,涉及到相互交织的语义反馈回路。虽然是封闭的,但它们并不能阻止基因组的延长,比如通过水平遗传转移,这增加了信息的数量。通讯作者:gassrard Battail,退休于巴黎E.N.S.T。电子邮件:gb@gerard.battail.name。生命是信息和物质的相互作用,因此它的语义特殊性,冗余性,因此它的纠错能力。因此,关闭语义反馈循环并不会阻止进化:可以添加新的结构,从而提高对错误的适应能力。再生失败是非常罕见的,如果它所指定的表型经受住了达尔文的选择,就会导致一个广泛不同的基因组产生一个新物种。提出了语义反馈循环(因此可能是生命)起源的一种可能情况。
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引用次数: 1
Analysing the Effect of Low Level Laser Therapy on Bone Histomorphometry in Rats 低水平激光治疗对大鼠骨组织形态学的影响分析
Pub Date : 2021-07-05 DOI: 10.9734/BPI/RRAB/V11/10521D
S. Adel, K. Ayad, A. Shaheen
The aim of this study was to assess the histological effect of Low Level Laser Therapy (LLLT) (904 nm) on the repair of standardized bone defects on the femur of rats. Sixty male wistar rats were assigned into two equal groups. Group (A: laser group) and group (B: control group). A surgical fracture was done in middle third of femur of all rats. In group (A) a continuous wave 904 nm infrared laser was applied at dose 4 j/cm 2 at fracture site immediately post operative for 7 sessions, each session was 5 minutes. The animals were killed by over dose of general anesthesia on the 15th,30th and 45th days after surgery, The specimens were processed and stained with Hematoxylin-eosin (H/E ), special stain Masion trichrome and analyzed by light microscopy. The descriptive analysis of histological imaging showed greater degree of new bone formation, osteoblastic surface and collagen fiber in the irradiated group when compared with the control group. Based on the obtained results, this study concluded that LLLT was efficient in promoting bone healing, and increasing new bone formation in the process of surgically fractured femur in animal study.
本研究旨在探讨904 nm低水平激光治疗(LLLT)对大鼠股骨标准化骨缺损修复的组织学影响。60只雄性wistar大鼠分为两组。A组为激光组,B组为对照组。所有大鼠股骨中间三分之一处手术骨折。A组术后即刻在骨折部位应用904 nm连续波红外激光,剂量为4 j/ cm2,连续7次,每次5分钟。术后第15、30、45天采用超剂量全麻处死,标本经苏木精-伊红(H/E)染色、Masion三色染色,光镜下分析。组织学影像学描述性分析显示,与对照组相比,放疗组新生骨形成程度、成骨细胞表面和胶原纤维更大。基于上述结果,本研究在动物实验中得出LLLT在股骨手术骨折过程中具有促进骨愈合和增加新骨形成的作用。
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引用次数: 2
Circulating Nucleic Acids: Potential Biomarkers of Male Infertility 循环核酸:男性不育的潜在生物标志物
Pub Date : 2021-07-05 DOI: 10.9734/BPI/RRAB/V11/6518D
M. Mbaye, B. E. Khalfi, Achraf Zakaria, Mustafa Zakaria, N. Louanjli, A. Soukri
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引用次数: 0
A Morphological Comparison between Northern (Salvelinus malma) and Southern (Salvelinus curilus) Dolly Varden Chars (Salmoniformes, Salmonidae) 北方Salvelinus malma和南方Salvelinus curilus的形态比较(鲑形,鲑科)
Pub Date : 2021-07-05 DOI: 10.9734/BPI/RRAB/V11/10713D
N. S. Romanov
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引用次数: 1
Determination of Hydrogen Peroxide Photoproduction by a Marine Cyanobacterium Oscillatoria boryana BDU 92181 with Potential Use in Bioremediation 海洋振荡蓝细菌BDU 92181对过氧化氢光能的测定及其在生物修复中的潜在应用
Pub Date : 2021-07-05 DOI: 10.9734/BPI/RRAB/V11/10925D
D. Kalavathi, G. Subramanian
The present study was aimed to find out the ability of the marine cyanobacterium Oscillatoria boryana BDU 92181 to produce H2O2 and to optimize its photoproduction with a view to harness its potential for decolorization of distillery effluent. The organism decolorized distillery effluent (5% V/V) by about 60% in 30 days. The mechanism of decolorization is postulated to be due to the production of hydrogen peroxide and molecular oxygen released by the cyanobacterium during photosynthesis. The effects of light intensity as well as different enhancers and inhibitors on the production of H2O2 in this organism were studied. Our results showed that, riboflavin and MnSO4 positively influenced H2O2 production. Sodium metabisulphite and potassium cyanide inhibited H2O2 production.
本研究的目的是找出海洋蓝藻振荡藻BDU 92181产生H2O2的能力,并优化其光合作用,以期利用其对蒸馏废水的脱色潜力。该生物在30天内将蒸馏废水(5% V/V)脱色约60%。脱色的机制被认为是由于蓝藻在光合作用过程中释放的过氧化氢和分子氧的产生。研究了光照强度及不同促进剂和抑制剂对该菌H2O2生成的影响。结果表明,核黄素和MnSO4正影响H2O2的生成。焦亚硫酸钠和氰化钾抑制H2O2的生成。
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引用次数: 0
Recent Local Birch Forest (Betula pubescens ssp. czerepanovii) Evolution in the Treeline Ecotone of the Swedish Scandes-response to Earlier Snow-melt 最近的当地白桦林(桦短毛)。瑞典森林交错带的演变——对早期融雪的响应
Pub Date : 2021-07-05 DOI: 10.9734/BPI/RRAB/V11/10488D
L. Kullman
In a context of recent climate change, the conversion of a restricted area of treeless alpine/subalpine tundra to mountain birch forest (Betula pubescens ssp. czerepanovii) was studied by repeat photography, demographic analysis in combination with tree growth surveillance in permanent plots. In addition, flora change was recorded within the emerging birch forest stand. The study was initiated in 1980, when a large snow bank still covered the site well into mid-July. Climate warming and associated enhanced snow melt since the early 20th century has made the snow disappear earlier during most summers. In response, a fairly dense population of seed-regenerated low-growing birch saplings gradually emerged. The population stagnated in average height until the early 1980s, when height growth and recruitment accelerated. Thereafter, a dense stand of tree-sized birches emerged. Concurrently, the character of the ground cover transformed from alpine snow bed to subalpine birch forest, as the snow has melted increasingly early, in combination with the presence of a shading tree layer. Earlier snow melt facilitated the establishment of scattered saplings of Pinus sylvestris. Possibly, an analogous course of patchy elevational subalpine forest expansion may be suggested as a reasonable option in a hypothetical case of further climate warming. The establishment of this forest stand may bear some resemblance to the evolution if the first Holocene mountain birch forests.
在最近气候变化的背景下,将无树的高山/亚高山冻土带限制区域转变为山地白桦林(Betula pubescens ssp.)。采用重复摄影、人口统计学分析和树木生长监测相结合的方法,在固定样地对Czerepanovii进行了研究。此外,还记录了新生桦林林分的植物区系变化。这项研究开始于1980年,当时一大片积雪一直覆盖到7月中旬。自20世纪初以来,气候变暖和相关的积雪融化加剧,使大多数夏季的积雪消失得更早。作为回应,一个相当密集的种群种子再生低生长桦树树苗逐渐出现。人口的平均身高停滞不前,直到20世纪80年代初,身高增长和招聘加速。此后,出现了一大片树木大小的桦树。同时,由于积雪融化越来越早,加上遮阳树层的存在,地面覆盖的特征从高山雪床转变为亚高山桦林。早期的融雪促进了散落的西尔维斯特松树苗的生长。也许,在气候进一步变暖的假设情况下,一个类似的海拔亚高山森林扩张的斑块过程可能被认为是一个合理的选择。该林分的形成与第一全新世山地白桦林的演化有一定的相似之处。
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引用次数: 2
Investigating the Anti-diabetic Effect of Leucaena leucocephala Linn. (Ipil-Ipil) Seed Extract on Albino Mice 白头银合欢抗糖尿病作用的研究。(Ipil-Ipil)种子提取物对白化小鼠的作用
Pub Date : 2021-07-05 DOI: 10.9734/BPI/RRAB/V11/2680F
Elchin R. Juanico, A. A. Flores
An experiment utilizing the Randomized Complete Block Design (RCBD) was done to prove the anti-diabetic effect of Leucaena leucocephala Linn. (Ipil-ipil) seed extract on albino mice as test animals. The study also aimed to detect the phytochemicals present in the extract, ascertain its physical properties, and compare its effect among three concentration levels and the positive control, a commercially prepared anti-hyperglycemic drug.Analysis of the extract‟s chemical properties showed the presence of alkaloid, flavonoid, saponin, tannin, and phenolic compounds; anthraquinone and steroid were not detected. The extract‟s color was orange, with a pleasant odor, a pH of 5.44, and was found to be miscible in both water and acetone, but was immiscible in chloroform. Among the three extract concentration levels used, 50% level was found to be most effective in reducing blood glucose levels (BGL) in the experimental animals, while the pure extract (100% concentration) was the least effective. However, reductions in BGL were not significantly different among the concentration levels and that of the commercial drug. Thus, it is clear that Leucaena leucocephala Linn has anti-diabetic potentials which are comparable to the commercial anti-hyperglycemic drug Metformin.It is recommended that other parts of the plant be also tested for its anti-diabetic potentials taking into consideration also the detection of other secondary metabolites which may be present in the plant parts, and evaluating its other potential applications.
采用随机完全区组设计(RCBD)验证了白头合欢的抗糖尿病作用。(il-ipil)种子提取物对白化小鼠的作用。该研究还旨在检测提取物中存在的植物化学物质,确定其物理性质,并比较其在三种浓度水平和阳性对照(一种市售的抗高血糖药物)中的效果。化学性质分析表明,提取液中含有生物碱、类黄酮、皂苷、单宁和酚类化合物;未检出蒽醌和类固醇。该提取物的颜色为橙色,气味宜人,pH值为5.44,在水和丙酮中均可混溶,但在氯仿中不混溶。在三种不同浓度的提取物中,50%的浓度对实验动物的血糖水平(BGL)最有效,而纯提取物(100%浓度)的效果最差。然而,在不同浓度水平下,BGL的降低与商业药物没有显著差异。因此,很明显,白头银合子具有与市售的降糖药物二甲双胍相当的降糖潜力。建议对植物的其他部分也进行抗糖尿病潜力测试,同时考虑到可能存在于植物部分的其他次级代谢物的检测,并评估其其他潜在应用。
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引用次数: 1
Efficient Production of Osteopontin-Encapsulating Exosome by LPS Stimulated THP-1 Macrophages LPS刺激THP-1巨噬细胞高效生产骨桥蛋白包封外泌体
Pub Date : 2021-07-05 DOI: 10.9734/BPI/RRAB/V11/9601D
G. Bai, T. Matsuba, T. Niki, T. Hattori
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引用次数: 0
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Recent Research Advances in Biology Vol. 11
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