{"title":"ALLERGIC CONTACT DERMATITIS TO A COMMON TOPICAL ACNE TREATMENT - AN UNFAMILIAR MIMIC OF ANGIOEDEMA.","authors":"K Mullan, K Ferris, A Thompson, C Loughran","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":38815,"journal":{"name":"Ulster Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cc/e1/umj-91-03-167.PMC9720594.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10452547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vocation in medicine.","authors":"Michael Trimble","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":38815,"journal":{"name":"Ulster Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/75/b0/umj-91-02-65.PMC9200093.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10746640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nathan Gamble, Robert Blair, Sam Gray, Michael Hunter, Denis Harkin
We report a patient who presented with a rapidly expanding symptomatic tuberculous aortitis and mycotic pseudo-aneurysm of the infra-renal aorta, after intra-vesical BCG chemotherapy for bladder cancer, treated by required emergency open aneurysm repair. His case highlights this rare complication of intravesical BCG treatment, haematological seeding causing tuberculous aortitis and mycotic pseudo-aneurysm formation of the infra-renal aorta. It also illustrates successful treatment with emergency open surgery, local debridement of mycotic pseudoaneurysm, in-situ surgical reconstruction using a custom bovine-wrap interposition graft to create a neo-aorta and multi-agent anti-tuberculous chemotherapy.
{"title":"Tuberculosis Aortitis and Mycotic Pseudo-aneurysm of the Infra-renal Aorta after Intravesicular BCG Therapy.","authors":"Nathan Gamble, Robert Blair, Sam Gray, Michael Hunter, Denis Harkin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We report a patient who presented with a rapidly expanding symptomatic tuberculous aortitis and mycotic pseudo-aneurysm of the infra-renal aorta, after intra-vesical BCG chemotherapy for bladder cancer, treated by required emergency open aneurysm repair. His case highlights this rare complication of intravesical BCG treatment, haematological seeding causing tuberculous aortitis and mycotic pseudo-aneurysm formation of the infra-renal aorta. It also illustrates successful treatment with emergency open surgery, local debridement of mycotic pseudoaneurysm, in-situ surgical reconstruction using a custom bovine-wrap interposition graft to create a neo-aorta and multi-agent anti-tuberculous chemotherapy.</p>","PeriodicalId":38815,"journal":{"name":"Ulster Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e4/53/umj-91-02-92.PMC9200094.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40042234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CORN FLAKES IS THE CURE.","authors":"S R Raichura, M Nicol, R Brennan, D O'Kane","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":38815,"journal":{"name":"Ulster Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/83/fd/umj-91-02-117.PMC9200099.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10746644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stuart McIlwaine, Mark Haynes, Neal Morgan, Rajeev Shah, James Doyle
A female in her 80's presented to our Emergency Department following a fall. She reported general malaise, weight loss and raised inflammatory markers. Background included renal cell carcinoma 21 years previous, managed with radical nephrectomy. During her inpatient stay she had an episode of haematemesis. Upper GI endoscopy revealed a 3cm polypoidal lesion on the greater curve of the upper stomach. This had an irregular pit pattern endoscopically and was friable. Multiple biopsies revealed metastatic clear cell carcinoma of renal origin; the same sub-type as her previous renal tumour. This is a rare manifestation of metastatic renal cell carcinoma and from literature review, is only the 2nd case we can find with a lag time of >20 years from the initial diagnosis to presenting with metastatic gastric disease.
{"title":"Metastasis of Renal Cell Carcinoma to the Stomach Twenty One Years from Initial Diagnosis.","authors":"Stuart McIlwaine, Mark Haynes, Neal Morgan, Rajeev Shah, James Doyle","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A female in her 80's presented to our Emergency Department following a fall. She reported general malaise, weight loss and raised inflammatory markers. Background included renal cell carcinoma 21 years previous, managed with radical nephrectomy. During her inpatient stay she had an episode of haematemesis. Upper GI endoscopy revealed a 3cm polypoidal lesion on the greater curve of the upper stomach. This had an irregular pit pattern endoscopically and was friable. Multiple biopsies revealed metastatic clear cell carcinoma of renal origin; the same sub-type as her previous renal tumour. This is a rare manifestation of metastatic renal cell carcinoma and from literature review, is only the 2<sup>nd</sup> case we can find with a lag time of >20 years from the initial diagnosis to presenting with metastatic gastric disease.</p>","PeriodicalId":38815,"journal":{"name":"Ulster Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9f/b0/umj-91-02-95.PMC9200106.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40042236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah Small, Rachael Coulson, Robert Spence, Ian McAllister
Background: The COVID-19 pandemic is an evolving healthcare challenge causing secondary disruption of cancer services. Quantitative Faecal Immunochemical Testing (qFIT) has been established as a screening method in asymptomatic patients. We aim to assess its utility as a triage tool to prioritise investigations in symptomatic patients with suspected colorectal cancer.
Methods: At the commencement of the COVID-19 pandemic a database was established to include patients awaiting red flag outpatient consultation or colonic investigations and new red flag referrals from March to June 2020. Patients were supplied with qFIT kits and returned results categorised into 3 priority groups according to the qFIT value. Group 1 >150µg Hb/g, Group 2 ≥10 to ≤150µg Hb/g and Group 3 <10µg Hb/g. Subsequent colonic evaluation was offered by colonoscopy or cross-sectional imaging with urgency determined by qFIT priority group. When identified colorectal cancer, inflammatory bowel disease or high-risk polyps were recorded as "significant colorectal pathology."
Findings: Three hundred and seventeen patients were identified with data analysed on 290 patients. Colorectal malignancy was identified in 17 patients; 94% of these patients were in Group 1. A qFIT result >150 µg Hb/g had a sensitivity and specificity for colorectal cancer of 94.12% (95% CI 71.31-99.85) and 91.21% (95% CI 87.20-94.29) respectively. No malignancy was detected in Priority Group 3; negative predictive value of 100% (95% CI 98.06-100).
Conclusions: In symptomatic, suspect lower GI cancer patients qFIT is a useful adjunct for prioritising patients and can be used to determine the urgency of colorectal investigations.
背景:COVID-19大流行是一项不断演变的卫生保健挑战，导致癌症服务的二次中断。定量粪便免疫化学试验(qFIT)已被确立为无症状患者的筛查方法。我们的目的是评估其作为一种分类工具的效用，优先调查有症状的疑似结直肠癌患者。方法:在COVID-19大流行开始时建立数据库，包括2020年3月至6月等待红旗门诊或结肠调查的患者和新的红旗转诊患者。为患者提供qFIT试剂盒，并根据qFIT值将返回的结果分为3个优先组。第1组>150µg Hb/g，第2组≥10至≤150µg Hb/g，第3组结果:共鉴定出317例患者，分析了290例患者的数据。结直肠恶性肿瘤17例;其中94%的患者为第一组。qFIT结果>150µg Hb/g对结直肠癌的敏感性和特异性分别为94.12% (95% CI 71.31-99.85)和91.21% (95% CI 87.20-94.29)。优先组3未见恶性肿瘤;阴性预测值为100% (95% CI 98.06-100)。结论:在有症状的可疑下消化道肿瘤患者中，qFIT是确定患者优先级的有用辅助手段，可用于确定结直肠检查的紧迫性。
{"title":"Is qFIT a useful tool in prioritising symptomatic patients referred with suspect colorectal cancer in the COVID-19 era?","authors":"Sarah Small, Rachael Coulson, Robert Spence, Ian McAllister","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The COVID-19 pandemic is an evolving healthcare challenge causing secondary disruption of cancer services. Quantitative Faecal Immunochemical Testing (qFIT) has been established as a screening method in asymptomatic patients. We aim to assess its utility as a triage tool to prioritise investigations in symptomatic patients with suspected colorectal cancer.</p><p><strong>Methods: </strong>At the commencement of the COVID-19 pandemic a database was established to include patients awaiting red flag outpatient consultation or colonic investigations and new red flag referrals from March to June 2020. Patients were supplied with qFIT kits and returned results categorised into 3 priority groups according to the qFIT value. Group 1 >150µg Hb/g, Group 2 ≥10 to ≤150µg Hb/g and Group 3 <10µg Hb/g. Subsequent colonic evaluation was offered by colonoscopy or cross-sectional imaging with urgency determined by qFIT priority group. When identified colorectal cancer, inflammatory bowel disease or high-risk polyps were recorded as \"significant colorectal pathology.\"</p><p><strong>Findings: </strong>Three hundred and seventeen patients were identified with data analysed on 290 patients. Colorectal malignancy was identified in 17 patients; 94% of these patients were in Group 1. A qFIT result >150 µg Hb/g had a sensitivity and specificity for colorectal cancer of 94.12% (95% CI 71.31-99.85) and 91.21% (95% CI 87.20-94.29) respectively. No malignancy was detected in Priority Group 3; negative predictive value of 100% (95% CI 98.06-100).</p><p><strong>Conclusions: </strong>In symptomatic, suspect lower GI cancer patients qFIT is a useful adjunct for prioritising patients and can be used to determine the urgency of colorectal investigations.</p>","PeriodicalId":38815,"journal":{"name":"Ulster Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/27/e7/umj-91-02-79.PMC9200097.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40042235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Curiositas.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":38815,"journal":{"name":"Ulster Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/90/e4/umj-91-02-109.PMC9200095.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10746641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"J.A. Lindsay's Tonics and Tinctures for Cardiac Care (1889-1904).","authors":"Tracy Freudenthaler","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":38815,"journal":{"name":"Ulster Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a7/62/umj-91-02-104.PMC9200098.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10746639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"\"Sports and Exercise Medicine Physician?\"","authors":"Michael McLarnon, Neil Heron","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":38815,"journal":{"name":"Ulster Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/82/fc/umj-91-02-111.PMC9200104.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10746643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hannah L Anderson, John E Moore, Beverley C Millar
{"title":"COMMUNICATING RESEARCH FINDINGS TO PATIENTS:: Comparison of readability of Patient Lay Summaries written by eight clinical disciplines of the Cystic Fibrosis (CF) Multidisciplinary Team (MDT).","authors":"Hannah L Anderson, John E Moore, Beverley C Millar","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":38815,"journal":{"name":"Ulster Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/09/dc/umj-91-02-118.PMC9200100.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10746645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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