Pub Date : 2025-01-01DOI: 10.1016/j.neuarg.2024.11.005
Gloria Elena Orrego Soto , Jhoan Emmanuel Orjuela Quiroga , Juan José Londoño Aranzazu , José Mauricio Cárdenas Prieto , Leonardo Favio Montero Riascos
Encephalitis caused by herpes virus type 1 (HSV-1) is a serious neurological disease that can cause devastating complications. Among these, intracerebral hemorrhage is described as an unusual complication in the acute phase, which involves complex pathophysiological mechanisms that include transient hypertension and infectious vasculitis, mainly affecting the temporal lobes, generating intracranial hypertension syndrome and ultimately causing death.
In this report, we describe two clinical cases of immunocompetent patients who presented HSV-1 encephalitis with subsequent development of intracerebral hemorrhage, resulting in fatal outcomes. These cases illustrate the importance of a timely diagnosis and management to avoid serious complications and reduce mortality.
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