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Diagnostic Accuracy of Haematological Scoring System in Paired cord Blood and Peripheral Venous Blood for early Detection of Neonatal Sepsis – A Prospective Analytical Study 配对脐带血和外周静脉血血液学评分系统诊断新生儿败血症的准确性-一项前瞻性分析研究
Q4 Medicine Pub Date : 2023-09-10 DOI: 10.60086/jnps483
Gagandeep Shukla, Prachi Goyal, Sunil Arya
Introduction: Sepsis is one of the major causes of neonatal morbidity and mortality. Early recognition and diagnosis of early onset neonatal sepsis (EONS) is difficult. Hence, there is a need for early predictive screening method for EONS, for which Haematological Scoring System (HSS) is used. It comprises of total leucocyte count, immature / total neutrophil ratio, total PMN count, immature PMN count, degenerative changes in PMN and platelet count. Methods: 100 inborn neonates with two or more risk factors for EONS, chosen by sequential sampling method were included in this prospective analytical study. Blood samples were collected from umbilical cord and peripheral vein and analysed for haematological parameters. Blood cultures were performed as gold standard for diagnosing neonatal sepsis and sepsis screen was done to corroborate the diagnosis of EONS. Results: Out of 100 neonates, 21 had sepsis, 14 had probable sepsis and 65 had no sepsis. Among the variables of HSS it was observed that elevated I:T ratio, thrombocytopenia, elevated I:M ratio and elevated immature neutrophil count have shown significant correlation with EONS with statistically significant p values (p value < 0.05), with raised I:T ratio being highly sensitive in identifying neonatal sepsis and degenerative changes in neutrophils being highly specific. Conclusions: The HSS was found to be satisfactory in identifying EONS. It can be used as a simple, quick, cost effective and readily available screening test with decent sensitivity and high specificity, for detection of EONS.
败血症是新生儿发病和死亡的主要原因之一。早期识别和诊断早发性新生儿脓毒症(EONS)是困难的。因此,有必要采用血液学评分系统(HSS)对EONS进行早期预测筛查。它包括白细胞总数、未成熟/总中性粒细胞比率、总PMN计数、未成熟PMN计数、PMN退行性变化和血小板计数。 方法:采用序贯抽样方法选取100例存在两种及以上EONS危险因素的新生儿进行前瞻性分析研究。采集脐带和外周静脉血样,分析血液学参数。血培养作为诊断新生儿败血症的金标准,并进行败血症筛查以证实EONS的诊断。 结果:100例新生儿中败血症21例,可能败血症14例,无败血症65例。HSS变量中,I:T比值升高、血小板减少、I:M比值升高、未成熟中性粒细胞计数升高与EONS有显著相关性,p值有统计学意义(p值<0.05), I:T比值升高对新生儿脓毒症的识别高度敏感,中性粒细胞退行性改变具有高度特异性。 结论:HSS对EONS的鉴别效果满意。它可以作为一种简单、快速、经济、容易获得的筛选试验,具有良好的灵敏度和高特异性,用于检测EONS。
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引用次数: 0
Effectiveness of Video-Assisted Distraction Technique in Reduction of Pain Among Preschool Children Undergoing Vein Puncture 视频辅助牵张技术减轻学龄前儿童静脉穿刺疼痛的效果
Q4 Medicine Pub Date : 2023-09-10 DOI: 10.60086/jnps484
Tulashi Adhikari Mishra, Aastha Subedi
Introduction: Vein puncture is an invasive but common procedure for children, often accompanied by pain, fear and anxiety and refuse to cooperate. Distraction technique is one of the non-pharmacological methods of controlling pain. The objective of this study was to find the effectiveness of video assisted distraction technique in reduction of pain among preschooler children. Methods: Quasi experimental study was conducted in Bharatpur Hospital, Chitwan, Nepal. 108 preschooler children consisting of 54 children in each experimental and control group selected by non-probability purposive sampling technique were enrolled in the study. Structured pain scale was used to collect data in both groups. Animated cartoon video was shown only to experimental group five minutes prior to until the vein puncture was over. Data analysis was done using descriptive statistics and inferential statistical tests. Results: In experimental group, 59.2% had moderate pain whereas 68.5% in control group had severe pain. The pain score of experimental group was significantly lower than that of control group at p = 0.05 with the mean value of experimental and control group 6.85 ± 0.79 and 7.25 ± 0.87 respectively. Conclusions: Distraction is an effective technique for children undergoing vein puncture in order to alleviate pain level during vein puncture
儿童静脉穿刺是一种有创但常见的手术,常伴有疼痛、恐惧、焦虑和拒绝配合。分散注意力技术是一种非药物控制疼痛的方法。本研究的目的是发现视频辅助分心技术在减轻学龄前儿童疼痛方面的有效性。方法:在尼泊尔Chitwan市Bharatpur医院进行准实验研究,采用非概率目的抽样方法选取108名学龄前儿童,实验组和对照组各54名。采用结构化疼痛量表收集两组数据。在静脉穿刺结束前5分钟,只给实验组播放动画视频。数据分析采用描述性统计和推理统计检验。 结果:实验组有中度疼痛的占59.2%,对照组有重度疼痛的占68.5%。实验组疼痛评分显著低于对照组,p = 0.05,实验组和对照组的平均值分别为6.85±0.79和7.25±0.87。结论:牵张术是减轻儿童静脉穿刺疼痛的有效方法
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引用次数: 0
Cerebral Venous Sinus Thrombosis in a Child with Iron Deficiency Anaemia 缺铁性贫血儿童脑静脉窦血栓形成
Q4 Medicine Pub Date : 2023-09-10 DOI: 10.60086/jnps496
Ly Cong Tran, Chuong Nguyen-Dinh-Nguyen, Phuong Minh Nguyen
Children who have cerebral venous sinus thrombosis (CVST) are at risk for both emergency and long-term neurological effects. Non-specific symptoms like fever, altered mental status, and localized neurological abnormalities define it. Infection, trauma, prothrombotic diseases and, most critically, iron deficiency anaemia (IDA) are etiologic factors. IDA, which is frequently brought on by excessive cow milk consumption in newborns and toddlers, is a preventable risk factor for CVST. We discuss the case of a 32-month-old female who presented with lethargy and hemiparesis, and was diagnosed with CVST in the context of IDA.
患有脑静脉窦血栓形成(CVST)的儿童有急诊和长期神经系统影响的风险。非特异性症状,如发热,精神状态改变和局部神经异常。感染、创伤、血栓形成前疾病和最严重的缺铁性贫血(IDA)是病因。IDA通常由新生儿和幼儿过量饮用牛奶引起,是CVST的一个可预防的危险因素。我们讨论的情况下,32个月大的女性谁提出嗜睡和偏瘫,并被诊断为CVST在IDA背景下。
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引用次数: 0
Spectrum of Paediatric Dermatoses in a Private Medical College 私立医学院儿科皮肤病谱
Q4 Medicine Pub Date : 2023-09-10 DOI: 10.60086/jnps493
Ravi Bhatia, Shivani Bhardwaj, Sarat Anandh, Dinesh Rajwaniya
Introduction: Dermatoses in children puts a huge burden on the parents as well as their development. Severity of these dermatoses vary from location to location. Environment plays an important role, especially in children and presentation of these dermatoses maybe quite different than those in adults. Methods: This is a six months prospective study. All children who presented to the Paediatrics / Dermatology OPD with any skin ailment were included. Diagnosis was done clinically, investigations if required were done. Based on age, cases were divided into six groups. Skin disorders were categorized into 17 groups. The demographic data and other clinical details were recorded on a pre-designed performa. Results: 206 children were included in our study. Males were 136 (66.01%) and females were 70 (33.98%) with M:F ratio 1.94:1. The spectrum of skin diseases were infections and exanthems (40.29%), eczematous diseases (19.41%), disorders of sebaceous and sweat glands (13.10%), papulosquamous diseases (6.31%), hypersensitivity syndromes (5.82%), disorders of pigmentation (5.33%), disorders of hair and nail (3.39%), cutaneous tumor and tumor syndromes (1.94%), vascular disorders (1.45%), disorders of cornification (0.97%), photo-dermatoses(0.97%), histiocytosis and malignant skin tumors (0.48%), and miscellaneous (0.48%). Dermatoses according to age were neonatal (0.97%), infant (4.36%), toddlers (9.70%), preschool (18.44%), school-age-children (30.58%), and adolescents (35.92%). Conclusions: Skin infections and infestations being the majority explains the status of developing countries like India. This study can help identify (or diagnosing) and treating common dermatological conditions in children and this would also sensitize our fellow paediatricians to this common but often neglected aspect of childcare.
儿童皮肤病给家长和儿童的发展带来了巨大的负担。这些皮肤病的严重程度因部位而异。环境起着重要的作用,特别是在儿童中,这些皮肤病的表现可能与成人有很大的不同。方法:这是一项为期六个月的前瞻性研究。所有到儿科/皮肤病门诊就诊的儿童均包括在内。临床诊断,必要时进行调查。根据年龄,病例分为六组。皮肤病被分为17组。人口统计数据和其他临床细节记录在预先设计的表演中。 结果:206名儿童纳入我们的研究。男性136例(66.01%),女性70例(33.98%),M:F比为1.94:1。皮肤病的类型依次为:感染和发疹(40.29%)、湿疹(19.41%)、皮脂腺和汗腺疾病(13.10%)、丘疹鳞状疾病(6.31%)、过敏综合征(5.82%)、色素沉着障碍(5.33%)、毛发和指甲疾病(3.39%)、皮肤肿瘤和肿瘤综合征(1.94%)、血管疾病(1.45%)、角质化疾病(0.97%)、光性皮肤病(0.97%)、组织细胞增多症和恶性皮肤肿瘤(0.48%)、杂项(0.48%)。皮肤病按年龄分类为新生儿(0.97%)、婴幼儿(4.36%)、幼儿(9.70%)、学龄前儿童(18.44%)、学龄儿童(30.58%)、青少年(35.92%)。结论:皮肤感染和感染是大多数解释像印度这样的发展中国家的现状。这项研究可以帮助识别(或诊断)和治疗儿童常见的皮肤病,这也将使我们的儿科医生同事对儿童保育中这一常见但经常被忽视的方面更加敏感。
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引用次数: 0
Retrieval of Broken Umbilical Venous Catheter Fragment in a VLBW Neonate 1例VLBW新生儿脐静脉导管断片抢救
Q4 Medicine Pub Date : 2023-09-10 DOI: 10.60086/jnps500
Md Habibullah SK, Bijan Saha, Ashadur Zamal, Sayantan Saha
Fracture of umbilical venous catheters is a serious uncommon complication. We are reporting a 31+4 week male neonate weighing 1390 gm with a broken umbilical venous catheter and successful retrieval of the catheter by an open surgical technique.
摘要脐静脉导管断裂是一种罕见的严重并发症。我们报告一例31+4周新生儿,体重1390 gm,脐静脉导管破裂,通过开放手术技术成功取出导管。
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引用次数: 0
Hand Washing – its Awareness and Practices Among School Children and Facilities Available in Rural Government Schools of District Rohtak, Haryana 哈里亚纳邦罗塔克县农村政府学校的洗手意识和实践情况
Q4 Medicine Pub Date : 2023-09-10 DOI: 10.60086/jnps487
None Anvesha, B M Vashisht, Arup Saha, None Jyotsana, None Pratibha
Introduction: Hand washing with soap (HWWS) is one of the single most cost-effective public health interventions. HWWS is effective in reducing diarrhea and can reduce its risk up to 48% and acute respiratory infections by more than 20%. Government of India launched Swachh Bharat Swachh Vidyalaya program, which also provided guidelines for hand washing i.e., availability of soap at hand washing stations, hand washing to be done before mid-day meal and also after use of toilet or urinal. The objective of the study was to assess knowledge and practices of hand washing among school children along with adequacy of available hand washing facilities and contributors responsible for it. Methods: A descriptive cross-sectional study was carried out in all Government schools of Lakhan Majra block, Rohtak, Haryana, India. Thirty-Eight schools for provision of facilities and 613 students for assessing knowledge, practice and behavior change were included in the study employing stratified random sampling technique. Semi-structured interview schedule was used for data collection. Results: All schools had hand washing facilities. Soap was available in 63.2% and 97.2% students knew benefits of hand washing while 88.9% of them were promoting it also. Less than one fifth of the students could demonstrate the correct steps of hand washing. Conclusions: Majority of students were aware of washing hands before and after critical times. Soap availability in schools was inadequate
用肥皂洗手是最具成本效益的公共卫生干预措施之一。HWWS可有效减少腹泻,并可将腹泻风险降低48%,将急性呼吸道感染风险降低20%以上。印度政府启动了Swachh Bharat Swachh Vidyalaya计划,该计划还提供了洗手指南,即洗手站有肥皂,中午吃饭前洗手,上厕所或便池后也要洗手。该研究的目的是评估学龄儿童的洗手知识和实践,以及可用洗手设施的充分性和负责人员。方法:在印度哈里亚纳邦罗塔克拉汗马吉拉街区的所有公立学校进行描述性横断面研究。采用分层随机抽样的方法,对38所提供设施的学校和613名评估知识、实践和行为改变的学生进行了研究。数据收集采用半结构化访谈计划。 结果:所有学校均设有洗手设施。63.2%的学生有肥皂,97.2%的学生知道洗手的好处,88.9%的学生也在推广洗手。只有不到五分之一的学生能演示正确的洗手步骤。结论:大多数学生在关键时刻前后都意识到洗手的重要性。学校的肥皂供应不足
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引用次数: 0
Feasibility of Telemedicine for Follow up of Children with Established Seizure Disorder- A Tertiary Care Center Prospective Study 远程医疗对癫痫患儿随访的可行性——三级医疗中心前瞻性研究
Q4 Medicine Pub Date : 2023-09-10 DOI: 10.60086/jnps486
Luna Bajracharya, Merina Shrestha
Introduction: Medical information exchanged via electronic communications to improve a patient’s clinical health status by a physician without in-patient visit is telemedicine. Control of seizures with antiepileptic drugs, reassurance for compliance to drugs, regular monitoring of adverse effects of drugs in patient with established seizure can be possible through telemedicine. The main objective of this study was to evaluate feasibility of telemedicine for follow up of children with established seizure disorder. Methods: This study was conducted among children of age one to 16 years with an established seizure due to any cause presenting to the Paediatric Neurodevelopmental OPD of Tribhuvan University Teaching Hospital (TUTH) between October 1, 2018 and September 30, 2020. Mobile phone as a modality of telemedicine was used to inquire about seizure every month for 12 months and whenever necessary. Results: When parameters as seizure control, total cost and time spent per hospital visit, distance to TUTH were analyzed, more than 75% caregivers were satisfied with telemedicine. Greater age, appropriate development, focal onset of seizure, normal electroencephalogram and seizure adequately controlled by single antiepileptic drug were the favorable factors in better seizure control in children using telemedicine. Conclusions: Telemedicine for follow up of children with established seizure disorder seems to be a feasible and satisfactory option when implemented with caution and proper patient selection as it decreases unnecessary high expenses and time to hospital visit
通过电子通信交换医疗信息以改善患者的临床健康状况的医生无需住院访问是远程医疗。通过远程医疗,可以使用抗癫痫药物控制癫痫发作,保证药物依从性,定期监测已确定癫痫发作的患者的药物不良反应。本研究的主要目的是评估远程医疗在癫痫发作障碍患儿随访中的可行性。 方法:本研究是在2018年10月1日至2020年9月30日期间在特里布万大学教学医院(TUTH)儿科神经发育OPD就诊的1至16岁儿童中进行的。以手机作为远程医疗的一种方式,在12个月内每月以及必要时查询癫痫发作情况。 结果:对癫痫发作控制、每次就诊总费用和时间、到TUTH的距离等参数进行分析,75%以上的护理人员对远程医疗感到满意。年龄较大、发育适宜、局灶性发作、脑电图正常、单一抗癫痫药物控制癫痫发作是远程医疗患儿癫痫控制较好的有利因素。 结论:远程医疗对已确诊癫痫发作的儿童进行随访是一种可行且令人满意的选择,只要实施谨慎,患者选择得当,可以减少不必要的高额费用和住院时间
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引用次数: 0
Incidence of Acute Kidney Injury in 1 - 14 years old Critically ill Children in a Tertiary care Center 某三级医疗中心1 ~ 14岁危重儿童急性肾损伤发生率分析
Q4 Medicine Pub Date : 2023-09-01 DOI: 10.60086/jnps489
Vijaykumar Pooja, BM John, Suprita Kalra, Amit Devgan
Introduction:Acute Kidney injury (AKI) is associated with poor outcomes in critically ill hospitalized children. There are very few studies on incidence of AKI based on urine output criteria of KDIGO (Kidney Disease: Improving Global Outcome) and time lag between the fall in urine output and rise in serum creatinine. This study was therefore aimed at determining the same. Methods: A prospective study was conducted in the Department of Paediatrics of a tertiary care hospital. 171 critically ill children between one to 14 years who were admitted in PICU were enrolled. Hourly urine output and eight hourly serum creatinine levels were measured and incidence of AKI was calculated along with lag time between fall in urine output and rise in serum creatinine. Outcome of children with AKI was also studied. Data analysis was done using SPSS software version 25.0 and Microsoft excel 2007. Results: The mean age + SD of children in the study was 5.5 years ± 3.76 with a range of one to 14 years, with 62.6 % of them being boys. The incidence of AKI in the study population was 14.62%. The mean lag time between fall in urine output and rise in serum creatinine was found to be 13.21 hours. AKI had a significant association with mortality, use of nephrotoxic drugs, inotropes and mechanical ventilation. Conclusions: A significant number of critically ill children develop AKI and its occurrence portends a poor outcome. Utilization of the KDIGO reduced urine output criteria as a marker of AKI allows for early detection and intervention
急性肾损伤(AKI)与危重住院儿童的不良预后相关。基于KDIGO(肾脏疾病:改善整体预后)尿量标准和尿量下降与血清肌酐升高之间的时间差来研究AKI发生率的研究很少。因此,本研究旨在确定相同的。 方法:在某三级医院儿科进行前瞻性研究。171例1 ~ 14岁重症患儿入组PICU。测量每小时尿量和8小时血清肌酐水平,并计算AKI发生率,同时计算尿量下降和血清肌酐上升之间的滞后时间。对AKI患儿的预后也进行了研究。数据分析采用SPSS 25.0软件和Microsoft excel 2007. 结果:本组儿童平均年龄+ SD为5.5岁±3.76岁,年龄范围1 ~ 14岁,其中男孩占62.6%。AKI在研究人群中的发病率为14.62%。尿量下降与血清肌酐升高之间的平均滞后时间为13.21小时。AKI与死亡率、肾毒性药物、肌力药物和机械通气的使用有显著相关性。 结论:大量危重儿童发生AKI,其发生预示着预后不良。使用KDIGO减少尿量标准作为AKI的标志物,可以早期发现和干预
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引用次数: 0
Peutz-Jeghers Syndrome Causing Gastroduodenal Intussusception : A Rare Case Report Peutz-Jeghers综合征引起胃十二指肠肠套叠:一罕见病例报告
Q4 Medicine Pub Date : 2023-09-01 DOI: 10.60086/jnps499
Gyanendra Chaudhary, Sachin Agrawal, Situ Situ, Ananvay Dadu
Peutz-Jeghers syndrome (PJS) is a rare disease characterized by melanotic macular lesions over the pulp of fingers, in oral cavity mucosa, lips, and hamartomatous gastric and intestinal polyps. They usually present with intestinal intussusception or intestinal bleeding; gastroduodenal intussusception is an infrequent presentation. Endoscopic resection or complete surgical excision of the polyp is the treatment of choice. We here present a case of a seven year male with multiple gastric polyps presenting as gastric outlet obstruction.
Peutz-Jeghers综合征(PJS)是一种罕见的疾病,其特征是指髓、口腔黏膜、嘴唇、错构瘤性胃和肠息肉上的黑色黄斑病变。通常表现为肠套叠或肠出血;胃十二指肠肠套叠是一种罕见的表现。内镜切除或完全手术切除息肉是治疗的选择。我们在此报告一个七岁男性多发性胃息肉表现为胃出口梗阻的病例。
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引用次数: 0
Hyperpigmented Macules in an Indian boy: is it EDP or LPP ? - A Case Report 一个印度男孩的色素沉着斑:是EDP还是LPP ?-个案报告
Q4 Medicine Pub Date : 2023-09-01 DOI: 10.60086/jnps497
Sameeksha Chand, Anuj Malhotra
Erythema dyschromicum perstans (EDP) and Lichen planus pigmentosus (LPP) are both inflammatory disorders of pigmentation with unknown etiology and are difficult to differentiate clinically and histologicaly. There is no consensus on whether both entities are separate or belong to the same spectrum of cutaneous disorders. We present a 13 year old boy with mostly asymptomatic hyperpigmented lesions over body. The lesions were subsequently diagnosed as EDP after detailed examination and histopatholgical examination.
持久性变色红斑(EDP)和色素性扁平苔藓(LPP)都是一种病因不明的色素沉着炎症性疾病,临床和组织学上难以鉴别。对于这两种疾病是分开的还是属于同一种皮肤疾病,目前还没有达成共识。我们提出一个13岁的男孩,大多是无症状的色素沉着病变在身体。经详细检查和组织病理学检查后诊断为EDP。
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引用次数: 0
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Journal of Nepal Paediatric Society
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