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Morphological and genetic aspects of Marfan Syndrome as demonstrated by a case of death during pregnancy with the discovery of two de novo missense mutations in the FBN1 gene 一例妊娠期死亡病例证明的马凡氏综合征的形态学和遗传学方面,同时发现 FBN1 基因中存在两个新的错义突变
Q2 Social Sciences Pub Date : 2023-12-12 DOI: 10.18778/1898-6773.86.4.05
I. Aquila, Matteo Antonio Sacco, Silvia Boca, Donatella Malanga, Giuseppe Viglietto, Ludovico Abenavoli, Martino Maesani, E. Varotto, Francesco M. Galassi, P. Ricci
Marfan Syndrome (MFS) is an autosomal dominant disease caused in most cases by mutations in the FNB1 gene, which encodes for fibrillin 1. MFS does not alway shows typical phenotypic signs. Indeed, the occurrence of sudden death of unknown cause is increasingly seen in young adults without ante mortem preexisting pathology to explain the event. In many cases the diagnosis of Marfan Syndrome (MFS) is carried out post mortem, especially in cases where the disease’s external phenotype is absent. Here is reported a case of a young woman who died during a twin pregnancy investigated with medico-legal and forensic anthropological procedures. The autopsy showed the absence of a typical marfanoid habitus and the presence of a dissecting aneurysm of the aorta with histopathological degeneration of the aortic elastic fibers. The genetic investigation revealed two previously undetected de novo mutations of the FBN1 gene: c.T6181C: p.C2061R and c.G1415A: p.C472Y. This new mutations, together with a comprehensive analysis, demonstrates the existence of a causal relationship between these mutations and the dissecting aneurysm of the aorta. This also stresses the importance of a combined multidisciplinary approach to this condition which includes morphological and genetic studies.
马凡综合征(Marfan Syndrome,MFS)是一种常染色体显性遗传病,大多数病例是由编码纤维蛋白 1 的 FNB1 基因突变引起的。事实上,不明原因的猝死越来越多地发生在青壮年身上,而他们在死前并无病理表现。在许多情况下,马凡综合征(MFS)的诊断是在死后进行的,尤其是在缺乏疾病外部表型的情况下。这里报告的是一例年轻女性在双胎妊娠期间死亡的病例,通过医学法律和法医人类学程序进行了调查。尸检结果显示,她没有典型的马凡诺综合征体型,但存在主动脉夹层动脉瘤,且主动脉弹性纤维组织病理变性。遗传学调查发现了两个之前未发现的 FBN1 基因新突变:c.T6181C:p.C2061R 和 c.G1415A:p.C472Y。这些新的基因突变以及综合分析表明,这些基因突变与主动脉夹层动脉瘤之间存在因果关系。这也强调了采用多学科综合方法(包括形态学和遗传学研究)治疗这种疾病的重要性。
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引用次数: 0
Reliability of retrospective assessment of the age of first menstruation 回顾性评估初潮年龄的可靠性
Q2 Social Sciences Pub Date : 2023-12-11 DOI: 10.18778/1898-6773.86.4.06
R. Żarów, Agnieszka Woronkowicz, Barbara Spring, Małgorzata Kowal, J. Brudecki
The age of the first menstruation is one of the indicators for assessing the course of puberty. It is also a sensitive indicator of the economic situation of individual professional groups or societies, and the low average age of menarche is widely recognized as a marker of society’s well-being. The aim of the study was to analyse the reliability of the retrospective method of assessing the age at menarche by comparing the results to the age obtained from continuous research. Data regarding the age at menarche came from longitudinal somatic development and physical fitness studies conducted between 1976 and 2022. In 2022, 47 women were examined. In continuous studies, the prospective method was used in the assessment of the age of first menstruation while in the 2004 and 2022 studies a retrospective method was applied. Only in 4 out of 47 women the age of the first menstruation declared in 2004 and 2022 (the women were 32–34 and 50–52 years old, respectively) was consistent with the one found in continuous studies. In other cases, there was a discrepancy between the age found in continuous studies and self-reported in 2004 or 2022 or between the age stated in 2004 and 2022. Of those women who were present for the 2022 study, 36 had information about the age of first menstruation from continuous studies and the age of menarche in 2004 was given. For this sample the arithmetic mean and the standard deviation of the age at menarche were calculated. It was found that the retrospective method often used in the assessment of the age of the first menstruation is not fully reliable, as the average discrepancy in the assessment ranged from nearly 1 month (0.05 years) to over 2 months (0.19 years) compared to the prospective method. Women surveyed in 2004 determined the age of the first menstruation more accurately compared to statements obtained 18 years later from the same women. This study suggests that long-term memory (LTM) of a significant life event of every woman is unreliable, as indicated by the difference in the declared age of the first menstruation of women examined in 2004 and 2022, which, in individual cases, was up to 3, 4 or 5 years.
初潮年龄是评估青春期进程的指标之一。它也是反映个别职业群体或社会经济状况的敏感指标,平均初潮年龄低被广泛认为是社会福祉的标志。这项研究的目的是通过将评估初潮年龄的结果与连续研究得出的年龄进行比较,分析回顾性评估初潮年龄方法的可靠性。有关初潮年龄的数据来自 1976 年至 2022 年期间进行的纵向躯体发育和体能研究。2022 年有 47 名妇女接受了检查。在连续性研究中,采用了前瞻性方法评估初潮年龄,而在 2004 年和 2022 年的研究中则采用了回顾性方法。在 47 名妇女中,只有 4 名妇女在 2004 年和 2022 年宣布的初潮年龄(分别为 32-34 岁和 50-52 岁)与连续性研究中发现的年龄一致。在其他情况下,连续性研究发现的年龄与 2004 年或 2022 年自我报告的年龄不一致,或者 2004 年和 2022 年申报的年龄不一致。在参加 2022 年研究的妇女中,有 36 人从连续性研究中获得了初潮年龄的信息,并提供了 2004 年的初潮年龄。对这一样本计算了初潮年龄的算术平均数和标准差。结果发现,在评估初潮年龄时经常使用的回顾性方法并不完全可靠,因为与前瞻性方法相比,评估的平均差异从近 1 个月(0.05 岁)到超过 2 个月(0.19 岁)不等。2004 年接受调查的妇女与 18 年后从同一妇女那里获得的陈述相比,对初潮年龄的判断更为准确。这项研究表明,2004 年和 2022 年接受调查的妇女申报的初潮年龄存在差异,个别情况下差异高达 3 年、4 年或 5 年,这表明每位妇女对人生重大事件的长期记忆(LTM)并不可靠。
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引用次数: 0
Relationship between body sway and body build in healthy adult men and women 健康成年男女身体摇摆与体型之间的关系
Q2 Social Sciences Pub Date : 2023-12-06 DOI: 10.18778/1898-6773.86.4.04
A. Lipowicz, M. Bugdol, K. Graja, Katarzyna Nowakowska-Lipiec, K. Jochymczyk-Woźniak, Dobrochna Fryc, R. Michnik, A. Mitas
Studies investigating the relationship between balance ability and body size, build and proportions tend to concentrate on body mass and height rather than breadth parameters or size of individual body segments. The purpose of this study was to determine a relationship between the ability to keep balance and the size, build and proportions, based on breadth and length dimensions of the body in healthy adult men and women during a position of free standing. This study also aimed to investigate how the lack of visual control affects the analyzed relationship. The study group consisted of 102 adults of both sexes. The investigations encompassed anthropometric measurements of the body and the ability to keep balance. The analysis covered a of series anthropometric parameters, 9 indices of body proportions, mean velocity of the COP movement (MV) and ellipse area (EA). A statistical analysis of the results was carried out taking into consideration the division into groups due to sexes. The results of the Pearson correlation have revealed that there is a statistically significant correlation (weak or moderate degree) between anthropometric parameters of the body and stabilographic values. Results differ between sexes and depend on whether Romberg’s test was performed with open or closed eyes. The obtained results showed that the surface area of ellipse significantly depends on the dimensions of these body elements which relate to the position of the centre of mass. The obtained results, which differ depending on sex, show that the values of the body sways in a position of free standing depend on breadth and length dimensions of the body, visual control and the analyzed parameter of balance.
研究平衡能力与体型、体型和比例之间关系的研究往往集中在体重和身高上,而不是单个身体部位的宽度参数或大小。这项研究的目的是根据健康成年男性和女性在自由站立时身体的宽度和长度尺寸,确定保持平衡的能力与身材、体型和比例之间的关系。本研究也旨在探讨缺乏视觉控制如何影响所分析的关系。研究小组由102名男女成年人组成。调查包括人体测量和保持平衡的能力。分析了一系列人体测量参数、9个身体比例指标、COP运动平均速度(MV)和椭圆面积(EA)。考虑到按性别分组,对结果进行了统计分析。Pearson相关结果显示,人体测量参数与稳定值之间存在统计学上显著的相关性(弱或中等程度)。结果因性别而异,也取决于Romberg的测试是睁眼还是闭眼进行的。得到的结果表明,椭圆的表面积很大程度上取决于这些体元的尺寸,这些体元与质心的位置有关。所得到的结果因性别不同而不同,表明在自由站立位置的身体摇摆值取决于身体的宽度和长度尺寸,视觉控制和分析的平衡参数。
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引用次数: 0
A new perspectives on breastfeeding practice reconstruction in bioarchaeology – an oxygen isotopes study in an animal model 生物考古学中母乳喂养实践重建的新视角——动物模型中的氧同位素研究
Q2 Social Sciences Pub Date : 2023-10-10 DOI: 10.18778/1898-6773.86.3.08
Aleksandra Lisowska-Gaczorek, Beata Cienkosz-Stepańczak, Mirosław Furmanek, Krzysztof Szostek
Research using stable isotopes for the reconstruction of breastfeeding strategies are based on assumptions that have not yet been verified by experimental studies. Interpreting the results of isotope analysis is associated with a certain degree of uncertainty, mainly due to the lack of information on how isotopes are distributed in mothers, breast-fed and weaned offspring. Culinary practices also can affect the interpretation of isotope results. Considering positive correlation between oxygen isotope composition of drinking water and bone phosphates, experimental studies were carried out using rats as an animal model. The experiment showed that apatites of breast-fed offspring were enriched 1.6‰ in comparison to the values observed in their mothers. In the boiled water model, the difference was 1.8‰. On the basis of the animal model, it was estimated that the difference in 18O between mother and child in the human species may amount to approximately 2.7‰, and long-term intake of boiled liquid food and beverages will not compensate the difference. The experiment allowed observation of the effect of changes in isotope ratios to a change in trophic levels during breastfeeding and weaning, as well as the additional effect associated with the consumption of isotope enriched water during thermal treatment.
使用稳定同位素重建母乳喂养策略的研究是基于尚未得到实验研究验证的假设。对同位素分析结果的解释存在一定程度的不确定性,这主要是由于缺乏同位素在母亲、母乳喂养和断奶后代中如何分布的信息。烹饪方法也会影响同位素结果的解释。考虑到饮用水氧同位素组成与骨磷酸盐呈正相关关系,以大鼠为动物模型进行实验研究。实验表明,母乳喂养的后代的磷灰石含量比母体的磷灰石含量高1.6‰。在沸水模型中,差异为1.8‰。在动物模型的基础上,估计人类母亲和孩子之间的18O差异可能约为2.7‰,长期摄入煮沸的流质食物和饮料并不能弥补这一差异。该实验可以观察到同位素比例的变化对母乳喂养和断奶期间营养水平变化的影响,以及在热处理期间饮用富含同位素的水的额外影响。
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引用次数: 0
Factors affecting stunting among 3–12 years old girls of Purba Medinipur, West Bengal, India 影响印度西孟加拉邦普尔巴梅迪尼普尔3-12岁女孩发育迟缓的因素
Q2 Social Sciences Pub Date : 2023-10-06 DOI: 10.18778/1898-6773.86.3.07
Pikli Khanra, Raja Chakraborty, Kaushik Bose
Stunting is the impaired growth and development in children caused due to poor nutrition, recurrent infections and lack of psychosocial stimulus. Because stunting affects physical development and inhibits the child from attaining his full cognitive development as an adult, children may never regain the height lost due to stunting. Stunting (Low height-for-age) in infants and young children is a simple, wellknown indicator of undernutrition. The current study sought to determine the effects of socio-economic and demographic factors on the frequency of stunting among Bengalee girls. The study was carried out in the Deshopran block and Haldia municipality area (West Bengal, India). The total number of participants included in the study was 530 Bengalee girls. 53.39% (283) of study participants were urban residents while 46.61% (247) were rural residents. Stunted growth in children was defined as the height for a given age in children less than two standard deviations of the WHO Child Growth Standards. The prevalence of stunting among girls in our study was 11.13%. The predictor variables with substantial associations with stunting in the binary logistic regression (BLR) analyses were further used in the multiple binary logistic regression (MBLR) analyses. Odds ratios with 95% confidence intervals were used to calculate the stunting risk. Results showed that the risk of stunting was significantly associated with low birth weight, presence of younger brothers, a large number of family members and place of delivery. Improving maternal and child access to nutrient-rich food, decreasing infectious disease, and promoting women empowerment initiatives are the main recommendations for resolving the issue.
发育迟缓是由于营养不良、反复感染和缺乏社会心理刺激而导致的儿童生长发育受损。由于发育迟缓会影响身体发育,并抑制儿童成年后的全面认知发展,儿童可能永远无法恢复因发育迟缓而失去的身高。婴儿和幼儿发育迟缓(低于年龄身高)是一个简单而众所周知的营养不良指标。目前的研究试图确定社会经济和人口因素对孟加拉女孩发育迟缓频率的影响。该研究在Deshopran区块和Haldia直辖市(印度西孟加拉邦)进行。参与这项研究的总人数为530名孟加拉女孩。53.39%(283人)为城镇居民,46.61%(247人)为农村居民。儿童发育迟缓的定义是某一年龄儿童的身高低于世卫组织儿童生长标准的两个标准差。在我们的研究中,发育迟缓的女孩患病率为11.13%。在二元逻辑回归(BLR)分析中与发育不良有显著相关性的预测变量进一步应用于多元二元逻辑回归(MBLR)分析。使用95%置信区间的优势比来计算发育迟缓风险。结果显示,发育迟缓的风险与出生体重低、有弟弟、家庭成员多和分娩地点显著相关。解决这一问题的主要建议是改善孕产妇和儿童获得营养丰富的食物的机会、减少传染病和促进增强妇女权能倡议。
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引用次数: 0
Economic stress affects the human sex ratio: A retest of the Trivers–Willard hypothesis in Poland 经济压力影响人类性别比:波兰对特里弗斯-威拉德假说的重新检验
Q2 Social Sciences Pub Date : 2023-10-06 DOI: 10.18778/1898-6773.86.3.06
Artur Mikulec, Iwona Rosset, Elżbieta Żądzińska
This paper contributes to the verification of the Trivers–Willard hypothesis (TWH). Based on the TWH, observed sex (male-to-female) ratio at birth in a population is presumed to decline when parents experience economic stress. The empirical evidence so far is mixed. The research material consisted of data on the total numbers of live male and female births in the Polish population in the years 1995–2020. The data were used to produce semiannual time series for secondary sex ratio (SSR), and the sex ratio at birth (SRB). The variable describing the economic stress of households was percentage change in private consumption. The statistical method proposed by Catalano and Bruckner – expanded to include additional statistical analyses – was applied to retest the economic stress hypothesis. The analysis led to complementary ARMAX models, explaining SSR or SRB variance based on autoregression and the moving average process, as well as private consumption. The results indicate that periods of decreasing consumption favored mothers having daughters, while periods of increasing consumption favored mothers having sons. The number of “additional” male births resulting from improved economic conditions was calculated for the period of study. Consequently, the economic factor was shown to have a positive effect on the human sex ratio. At the same time, it should be noted that SSR and SRB reaction lags to consumption changes were different for Łódzkie Province (one year) and for Poland (two years). The obtained results led to the “correct” verification of the Trivers–Willard hypothesis (TWH): economic stress affected the SSR and SRB in Poland. Both SSR and SRB were useful in analyzing economic stress (a dual solution). The use of a greater density of data points was shown to improve analysis effects and increase the likelihood of a “positive” verification of the economic stress hypothesis.
本文为验证Trivers-Willard假说(TWH)做出了贡献。根据TWH,当父母经历经济压力时,人口中观察到的性别(男女)比率被认为会下降。迄今为止的经验证据好坏参半。研究材料包括1995-2020年波兰人口中男女活产总数的数据。利用这些数据制作了每半年一次的二次性别比(SSR)和出生性别比(SRB)时间序列。描述家庭经济压力的变量是私人消费的百分比变化。Catalano和Bruckner提出的统计方法——扩展到包括额外的统计分析——被用于重新检验经济压力假设。通过分析得到互补的ARMAX模型,解释了基于自回归和移动平均过程的SSR或SRB方差,以及私人消费。结果表明,消费减少的时期有利于生女儿的母亲,而消费增加的时期有利于生儿子的母亲。在研究期间,计算了因经济条件改善而“额外”出生的男性人数。因此,经济因素被证明对人类性别比例有积极的影响。同时,应该指出的是,SSR和SRB对消费变化的反应滞后在Łódzkie省(1年)和波兰(2年)是不同的。所得结果“正确”验证了Trivers-Willard假说(TWH):经济压力影响了波兰的SSR和SRB。SSR和SRB均可用于经济压力分析(双解)。使用更大密度的数据点可以改善分析效果,并增加对经济压力假设进行“积极”验证的可能性。
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引用次数: 0
The assessment of the relationship between the traits of temporal muscle and the massiveness of the supraorbital region of the Homo sapiens crania including the influence of the neurocranial shape and size of the occlusal surface of the upper molars – preliminary study 颞肌特征与智人颅眶上区质量关系的评估,包括神经颅形状和上磨牙咬合面大小的影响——初步研究
Q2 Social Sciences Pub Date : 2023-09-26 DOI: 10.18778/1898-6773.86.3.05
Wioletta Nowaczewska, Katarzyna Górka, Agata Cieślik, Mateusz Patyk, Urszula Zaleska-Dorobisz
The knowledge about the pattern of the relationship between the morphological variability of the supraorbital region of human skulls and the features of the temporal muscle is far from complete. The main aim of this study was to determine the relationships between the traits of human temporal muscle (i.e., its relative height and length) and the relative massiveness of the supraorbital region of the frontal bone with taking into account the potential influence of the neurocranial shape and the relative area of the occlusal surface of the upper molars. Skulls of African and Australian males (n = 44) exhibiting high variability in the massiveness of the supraorbital region, the presence of two types of the upper molars (first and second, n = 88) and a good state of the preservation of the braincase with the clearly visible inferior temporal line were examined. The qualitative scales were used to assess the degrees of the massiveness of the supraorbital regions. Metric traits of temporal muscle and that used to calculate the index of the neurocranial shape, size of the braincase and the facial skeleton were collected. Values of the occlusal areas of the molars were obtained using the ImageJ software. Spearman’s rank correlation and partial rank correlation analyses were performed. The results of our study showed the relationships between the traits of the temporal muscle and only the degree of the robusticity of most lateral part of the supraorbital area (trigonum). However, when the influences of the neurocranial shape and the relative occlusal area of molars were excluded, these relationships disappeared. The greatest importance of the neurocranial shape for the formation of the morphology of the trigonum was indicated. The results of the study were discussed from the perspective of the potential role of the temporal muscle as the part of the mastication apparatus for the development of the robusticity of the cranial supraorbital region.
关于人类颅骨眶上区形态变异与颞肌特征之间关系模式的认识还远远不够完整。本研究的主要目的是确定人类颞肌的特征(即相对高度和长度)与额骨眶上区域的相对质量之间的关系,同时考虑到神经颅形状和上磨牙咬合面相对面积的潜在影响。非洲和澳大利亚男性(n = 44)的颅骨在眶上区域的质量上表现出高度的变化,两种类型的上颌磨牙(第一和第二,n = 88)的存在,以及脑组织的良好保存状态,清晰可见的下颞线。采用定性量表评估眶上区肿块的严重程度。采集颞骨肌的度量特征及用于计算神经颅骨形状、颅脑大小和面部骨骼指数的度量特征。使用ImageJ软件计算磨牙的咬合面积。进行Spearman秩相关分析和部分秩相关分析。我们的研究结果显示了颞肌的特征与眶上大部分外侧区域(三角)的强健程度之间的关系。然而,当排除神经颅形状和磨牙相对咬合面积的影响时,这些关系就消失了。神经颅形对于三角肌形态的形成是最重要的。本文从颞肌作为咀嚼器官的一部分在颅眶上区健全性发育中的潜在作用的角度讨论了研究结果。
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引用次数: 0
Associations between birth season and lumbar spine bone mineral density in perimenopausal Polish women 波兰围绝经期妇女出生季节与腰椎骨密度之间的关系
Q2 Social Sciences Pub Date : 2023-09-22 DOI: 10.18778/1898-6773.86.3.04
Iwona Rosset, Anna Elżbieta Spinek, Michał Stuss, Ewa Sewerynek, Elżbieta Żądzińska
In European populations, the birth season significantly correlates with many biological features. It is thus possible that the observed clinical effects of bone metabolism disorders are a partial consequence of bone mineral density (BMD), modified by the season of prenatal development (the birth season). The aim of this study was to evaluate the relationship between the birth season and BMD among Polish women in perimenopausal age. A total of 653 Polish women aged 50.0–59.9 years were included in the study. BMDs of lumbar vertebrae were measured by dual-energy x-ray absorptiometry. Statistical analyses were based on measured lumbar BMD values, age, and body mass index (BMI). The analysis of variance (ANOVA) was applied to evaluate the season-related differentiation of mineral density of lumbar vertebrae. BMDs of lumbar vertebrae negatively correlated with age and positively with BMI. We regressed BMD on age and BMI and used the residuals as a measure of age- and BMI-independent lumbar BMD values. The ANOVA results showed that women born in summer had significantly lower BMD of the L1 vertebra compared to those born in autumn, regardless of age and BMI. The results of our study indicate the need to extend the group of risk factors for osteoporosis in Central Europeans with the season of woman’s birth.
在欧洲人群中,出生季节与许多生物学特征显著相关。因此,观察到的骨代谢紊乱的临床效果可能是骨矿物质密度(BMD)的部分后果,受产前发育季节(出生季节)的影响。本研究的目的是评估波兰围绝经期妇女出生季节与骨密度之间的关系。共有653名年龄在50.0-59.9岁之间的波兰妇女参与了这项研究。采用双能x线骨密度仪测定腰椎骨密度。统计分析基于测量的腰椎骨密度值、年龄和身体质量指数(BMI)。采用方差分析(ANOVA)评价腰椎矿物密度的季节相关分化。腰椎骨密度与年龄呈负相关,与BMI呈正相关。我们将骨密度随年龄和BMI进行回归,并使用残差作为与年龄和BMI无关的腰椎骨密度值的测量。方差分析结果显示,无论年龄和BMI如何,夏季出生的女性L1椎体骨密度明显低于秋季出生的女性。我们的研究结果表明,需要延长骨质疏松症的风险因素组在中欧妇女的出生季节。
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引用次数: 0
Low 2D:4D is associated with delayed age at menarche among women of Sikkim, India 低2D:4D与印度锡金妇女月经初潮年龄延迟有关
Q2 Social Sciences Pub Date : 2023-09-19 DOI: 10.18778/1898-6773.86.3.02
Nitish Mondal, Rebaka Rai
The index-finger and ring-finger ratio (2D:4D) is a potential biomarker that reflects prenatal hormonal exposure and thus has a long-term impact on reproductive health. The present study aims to determine the relationship between the 2D:4D (representing the prenatal hormonal environment, i.e., early androgen exposure) and early or delayed age at menarche among women in Sikkim, India. A total of one hundred nineteen Sherpa tribal women, ages 18–49, from the Soreng district of Sikkim, India, were included in the study using a stratified random sampling method. To calculate the 2D:4D ratio, the lengths of the index and ring fingers (2D and 4D) were measured using standard procedures. The category-wise mean comparison revealed that women with a more feminine 2D:4D ratio (in both left and right hand) had significantly earlier age at menarche (in years) compared to women with a more masculine 2D:4D ratio. The linear regression analysis revealed that the left 2D:4D was significantly related to menarche age. There is an association between the 2D:4D and menarche age, indicating a link between women’s reproduction patterns and the influence of the prenatal hormonal environment as an important factor in attaining an early or delayed menarcheal age.
食指和无名指的比例(2D:4D)是反映产前激素暴露的潜在生物标志物,因此对生殖健康具有长期影响。本研究旨在确定2D:4D(代表产前激素环境,即早期雄激素暴露)与印度锡金妇女月经初潮提前或延迟的关系。采用分层随机抽样的方法,研究了来自印度锡金Soreng地区的119名年龄在18-49岁的夏尔巴人部落妇女。为了计算2D:4D比值,使用标准程序测量食指和无名指(2D和4D)的长度。分类平均比较显示,与2D:4D比例更男性化的女性相比,2D:4D比例更女性化的女性(左手和右手)月经初潮的年龄(以年计)明显更早。线性回归分析显示,左侧2D:4D与月经初潮年龄显著相关。2D:4D与月经初潮年龄之间存在关联,表明妇女的生殖模式与产前荷尔蒙环境的影响之间存在联系,这是提前或推迟月经初潮年龄的一个重要因素。
{"title":"Low 2D:4D is associated with delayed age at menarche among women of Sikkim, India","authors":"Nitish Mondal, Rebaka Rai","doi":"10.18778/1898-6773.86.3.02","DOIUrl":"https://doi.org/10.18778/1898-6773.86.3.02","url":null,"abstract":"The index-finger and ring-finger ratio (2D:4D) is a potential biomarker that reflects prenatal hormonal exposure and thus has a long-term impact on reproductive health. The present study aims to determine the relationship between the 2D:4D (representing the prenatal hormonal environment, i.e., early androgen exposure) and early or delayed age at menarche among women in Sikkim, India. A total of one hundred nineteen Sherpa tribal women, ages 18–49, from the Soreng district of Sikkim, India, were included in the study using a stratified random sampling method. To calculate the 2D:4D ratio, the lengths of the index and ring fingers (2D and 4D) were measured using standard procedures. The category-wise mean comparison revealed that women with a more feminine 2D:4D ratio (in both left and right hand) had significantly earlier age at menarche (in years) compared to women with a more masculine 2D:4D ratio. The linear regression analysis revealed that the left 2D:4D was significantly related to menarche age. There is an association between the 2D:4D and menarche age, indicating a link between women’s reproduction patterns and the influence of the prenatal hormonal environment as an important factor in attaining an early or delayed menarcheal age.","PeriodicalId":39218,"journal":{"name":"Anthropological Review","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135061045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Linear Morphometric Analysis of Auricular Measurements of a Nigerian Igbo population 尼日利亚伊博人群耳廓测量的线性形态计量学分析
Q2 Social Sciences Pub Date : 2023-09-15 DOI: 10.18778/1898-6773.86.3.03
Gabriel Sunday Oladipo, Oghenefego Michael Adheke, Janet Nneoma Eke
The human ear (auricle) is an important body component in biometric studies and forensic identification. The purpose of this study was to evaluate linear auricular morphometric measurements of a Nigerian Igbo population. 300 participants (142 males to 158 females) of at least 16 years of age were randomly recruited from settlements in the South-Eastern states of Nigeria. The participants were made to sit in a Frankfort horizontal position and auricular measurements such as total ear height (TEH), ear width (EW), lobule height (LH) and lobule width (LW) were obtained using a digital vernier caliper (validated by calibrating to 0.01mm). The ear index (EI) and lobule index (LI) were calculated using the measurements. Data obtained were analyzed using the Statistical Package for the Social Sciences (SPSS version 23.0). The following mean values were recorded for males: TEH [Right (R) = 47.01±6.30, Left (L) = 46.24±5.85], EW (R = 25.06±4.14, L = 24.68±4.32), LH (R = 13.92±2.61, L = 13.99±2.18), LW (R = 12.99±2.30, L = 13.30±1.94), EI (R = 53.47±7.23, L = 53.28±6.69) and LI (R = 95.17±18.12, L = 96.80±18.56); for females, TEH (R = 48.25±6.83, L = 48.25±6.24), EW (R = 25.19±3.93, L = 24.57±4.21), LH (R = 14.44±2.67, L = 14.89±2.55), LW (R = 13.37±2.26, L = 13.78±2.04), EI (R = 52.50±6.85, L = 50.93±7.05) and LI (R = 94.60±19.59, L = 94.30±16.63). Gender differences were highly significant regarding total ear height, lobular length and width, as well as the ear index of the left auricle. This study provides a baseline data for auricular morphometrics of adult Nigerian Igbos and could be used as an ergonomic guide towards the creation of hearing aids in the future and to solve possible forensic issues associated with identification of remains.
人耳(耳廓)是生物识别研究和法医鉴定中重要的身体组成部分。本研究的目的是评估尼日利亚伊博人群的线性耳廓形态测量。300名至少16岁的参与者(142名男性至158名女性)从尼日利亚东南部各州的定居点随机招募。参与者被要求以法兰克福水平姿势坐着,并使用数字游标卡尺(校准到0.01mm)获得耳廓测量数据,如总耳高(TEH)、耳宽(EW)、小叶高度(LH)和小叶宽度(LW)。计算耳指数(EI)和小叶指数(LI)。获得的数据使用社会科学统计软件包(SPSS version 23.0)进行分析。男性TEH[右(R) = 47.01±6.30,左(L) = 46.24±5.85]、EW (R = 25.06±4.14,L = 24.68±4.32)、LH (R = 13.92±2.61,L = 13.99±2.18)、LW (R = 12.99±2.30,L = 13.30±1.94)、EI (R = 53.47±7.23,L = 53.28±6.69)、LI (R = 95.17±18.12,L = 96.80±18.56);女性TEH (R = 48.25±6.83,L = 48.25±6.24)、EW (R = 25.19±3.93,L = 24.57±4.21)、LH (R = 14.44±2.67,L = 14.89±2.55)、LW (R = 13.37±2.26,L = 13.78±2.04)、EI (R = 52.50±6.85,L = 50.93±7.05)、LI (R = 94.60±19.59,L = 94.30±16.63)。在总耳高、小叶长、宽以及左耳廓耳指数上,性别差异显著。该研究为成年尼日利亚伊博人的耳廓形态计量学提供了基线数据,可作为未来助听器制造的人体工程学指导,并可解决与遗骸鉴定相关的可能的法医问题。
{"title":"Linear Morphometric Analysis of Auricular Measurements of a Nigerian Igbo population","authors":"Gabriel Sunday Oladipo, Oghenefego Michael Adheke, Janet Nneoma Eke","doi":"10.18778/1898-6773.86.3.03","DOIUrl":"https://doi.org/10.18778/1898-6773.86.3.03","url":null,"abstract":"The human ear (auricle) is an important body component in biometric studies and forensic identification. The purpose of this study was to evaluate linear auricular morphometric measurements of a Nigerian Igbo population. 300 participants (142 males to 158 females) of at least 16 years of age were randomly recruited from settlements in the South-Eastern states of Nigeria. The participants were made to sit in a Frankfort horizontal position and auricular measurements such as total ear height (TEH), ear width (EW), lobule height (LH) and lobule width (LW) were obtained using a digital vernier caliper (validated by calibrating to 0.01mm). The ear index (EI) and lobule index (LI) were calculated using the measurements. Data obtained were analyzed using the Statistical Package for the Social Sciences (SPSS version 23.0). The following mean values were recorded for males: TEH [Right (R) = 47.01±6.30, Left (L) = 46.24±5.85], EW (R = 25.06±4.14, L = 24.68±4.32), LH (R = 13.92±2.61, L = 13.99±2.18), LW (R = 12.99±2.30, L = 13.30±1.94), EI (R = 53.47±7.23, L = 53.28±6.69) and LI (R = 95.17±18.12, L = 96.80±18.56); for females, TEH (R = 48.25±6.83, L = 48.25±6.24), EW (R = 25.19±3.93, L = 24.57±4.21), LH (R = 14.44±2.67, L = 14.89±2.55), LW (R = 13.37±2.26, L = 13.78±2.04), EI (R = 52.50±6.85, L = 50.93±7.05) and LI (R = 94.60±19.59, L = 94.30±16.63). Gender differences were highly significant regarding total ear height, lobular length and width, as well as the ear index of the left auricle. This study provides a baseline data for auricular morphometrics of adult Nigerian Igbos and could be used as an ergonomic guide towards the creation of hearing aids in the future and to solve possible forensic issues associated with identification of remains.","PeriodicalId":39218,"journal":{"name":"Anthropological Review","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135397451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Anthropological Review
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